CN218786218U - Cell collection transport box - Google Patents

Cell collection transport box Download PDF

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Publication number
CN218786218U
CN218786218U CN202223230222.1U CN202223230222U CN218786218U CN 218786218 U CN218786218 U CN 218786218U CN 202223230222 U CN202223230222 U CN 202223230222U CN 218786218 U CN218786218 U CN 218786218U
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China
Prior art keywords
box
liquid nitrogen
cell collection
stem cell
case lid
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CN202223230222.1U
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Chinese (zh)
Inventor
赵振峰
张蓉
武涛
王元锋
陈巧真
蔡玉玲
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Bokang Bioengineering Shandong Co ltd
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Bokang Bioengineering Shandong Co ltd
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Abstract

The utility model provides a cell collection transportation box relates to stem cell transportation technical field, including box, case lid and heat preservation, box top one side and case lid bottom one side swing joint, and the fixed joint in the outside of the inner wall of box and heat preservation. The utility model discloses, realized providing continuous liquid nitrogen for cryopreserving the cell to keep the inside stem cell cryopreserving temperature of box, storage performance when having promoted the stem cell transportation, and when bumping or rocking in the transportation, hang inside the box through four spring beams because of placing the rack of stem cell test tube, can effectively cushion the stem cell test tube, prevent that the stem cell test tube from striking box inner wall and causing the damage.

Description

Cell collection transport box
Technical Field
The utility model relates to a stem cell transportation technical field especially relates to a cell collection transport box.
Background
In regenerative medicine, stem cells are an advanced technology that can continuously secrete a variety of repair factors, or immunoregulatory factors, for the treatment of disease. Stem cell therapy is a process in which each patient's own cells are carefully cultured and then quality inspection, production, transportation, storage, etc. are performed in a labor-intensive manner, and therefore, a storage and transportation cassette used for the transportation of stem cells is very important.
Transport case is gathered to stem cell like chinese patent No. CN 214567580U, comprises a box bod, the top of box body is provided with the lid, the bottom fixedly connected with foam clamp plate of lid, the inside of box body is provided with interior box, the inside of interior box is provided with porous spacing, the bottom of box body is provided with the ice bag box, be provided with L type bolt between ice bag box and the box body jointly, the lid all is provided with the bulge loop with the top of ice bag box. In this device, L type bolt can be convenient for carry out the dismouting to the ice bag box, thereby be convenient for change the ice bag, the box compresses tightly first sealing washer in first spring can promote, the inside temperature of detection box body can be convenient for to the temperature-sensing ware, second sealing washer and bulge loop can make and seal between box body and the lid, simple structure can make the device have better leakproofness, the shock resistance, can be better preserve stem cells, thereby be convenient for transport.
Stem cell requires very high to the temperature of storage environment, only can make the cell be in the dormant state under the deep low temperature cryopreserved state, the enzyme in the cell is suppressed, ionization damage can not take place, just can cryopreserve for a long time, but among the prior art, adopt the ice bag box to arrange in the box body, the ambient temperature that can't make in the box body reaches the required low temperature of cryopreserving, and in the long-time storage transportation, the ice bag box can constantly melt because of the heat absorption, make the refrigerating capacity of ice bag box descend gradually, will greatly influence the stem cell cryopreserved effect.
SUMMERY OF THE UTILITY MODEL
The utility model aims at solving the adoption that exists among the prior art and in the box body was arranged in to the ice bag box, the ambient temperature that can't make in the box body reached and freezes and deposit required low temperature, and in long-time storage transportation, the ice bag box can constantly melt because of the heat absorption for the refrigerating capacity of ice bag box descends gradually, will greatly influence the problem of stem cell cryopreserving effect, and the transport box is gathered to the cell that provides.
In order to achieve the above purpose, the utility model adopts the following technical scheme: the utility model provides a cell collection transport case, includes box, case lid and heat preservation, box top one side and case lid bottom one side swing joint, and the fixed joint in the outside of the inner wall of box and heat preservation, the even integrated into one piece in inboard top of box has four lugs, every the bottom of lug is all rotated and is connected with the deflection head, and every deflection head bottom equal joint has the spring beam, the inside of heat preservation has hung the rack through four spring beams, the inside fixed mounting of rack has wireless temperature sensor, the inboard fixed joint in bottom of heat preservation has the liquid nitrogen fill, fixed surface installs the liquid nitrogen replenisher on the bottom half, the top fixed mounting of case lid has the relief valve.
Preferably, the liquid nitrogen replenisher includes the mount, the inboard fixed mounting of mount has a plurality of storage jar, and adjacent storage jar is linked together, and one of them storage jar an end intercommunication has the liquid nitrogen pump.
Preferably, the bottom of the fixing frame and the inner wall of the bottom of the box body are fixedly installed through bolts, the output end of the liquid nitrogen pump is communicated with an output pipe, and the top of the output pipe is fixedly connected with one side of the liquid nitrogen bucket in an inserting mode.
Preferably, one side electric connection of liquid nitrogen pump has the lithium cell, and liquid nitrogen pump one side bottom fixed mounting has the starter.
Preferably, a rotating shaft is fixedly mounted at the top of one side of the box body, and the top of the rotating shaft is rotatably connected with the bottom of one side of the box cover.
Preferably, the top of the box cover is fixedly provided with a handle, the other side of the box cover is rotatably connected with a lock catch, and the top of the other side of the box body is fixedly provided with a stud.
Preferably, the clamping groove is integrally formed on the outer side of the box body.
Compared with the prior art, the utility model discloses an advantage lies in with positive effect:
1. the utility model discloses in, when wireless temperature sensor detected that the inside temperature of box is higher than the predetermined temperature of stem cell cryopreserving, will control the liquid nitrogen pump through the starter and begin work for carry the liquid nitrogen that comes from the storage jar, in order to supply the liquid nitrogen to the liquid nitrogen fill, keep the inside stem cell cryopreserving temperature of box, realized providing continuous liquid nitrogen for cryopreserving the cell, storage performance when having promoted the stem cell transportation.
2. The utility model discloses in, when bumping or rocking in the transportation, hang inside the box through four spring arms because of the rack of placing the stem cell test tube, can effectively cushion the stem cell test tube to prevent that the stem cell test tube from striking box inner wall and causing the damage.
Drawings
FIG. 1 is a top view of one side of a cell collection and transport cassette according to the present invention;
FIG. 2 is a schematic view of the top view of the inside of the cell collection and transportation box according to the present invention;
FIG. 3 is an elevational cross-sectional view of the cell collection and transport cassette according to the present invention;
FIG. 4 is a schematic view of a part of a cross-sectional structure of a cell collection and transportation box according to the present invention;
fig. 5 is a schematic structural view of a liquid nitrogen replenisher of the cell collecting and transporting box of the present invention.
Illustration of the drawings: 1. a box body; 10. a card slot; 11. a stud; 12. a bump; 2. a box cover; 20. a grip; 21. locking; 22. a safety valve; 23. a rotating shaft; 3. a heat-insulating layer; 4. a spring lever; 40. a deflection head; 5. placing a rack; 50. a wireless temperature sensor; 6. a liquid nitrogen hopper; 7. a liquid nitrogen replenisher; 70. a fixed mount; 71. storing the tank; 72. a liquid nitrogen pump; 73. an output pipe; 74. a starter; 75. a lithium battery.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present invention more clearly understood, the present invention will be further described with reference to the accompanying drawings and examples. It should be noted that the embodiments and features of the embodiments of the present application may be combined with each other without conflict.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, however, the present invention may be practiced in other ways than those specifically described herein, and therefore the present invention is not limited to the limitations of the specific embodiments of the present disclosure.
Referring to fig. 1-5, the present invention provides a technical solution: the utility model provides a cell collection transport case, the power distribution box comprises a box body 1, case lid 2 and heat preservation 3, 1 top one side of box and 2 bottom one side swing joint of case lid, and the inner wall of box 1 and the outside fixed joint of heat preservation 3, the even integrated into one piece in inboard top of box 1 has four lugs 12, the bottom of every lug 12 is all rotated and is connected with deflection head 40, and every 40 equal joints in the bottom of deflection head have a spring beam 4, the inside of heat preservation 3 has hung rack 5 through four spring beams 4, when bumping or rocking in the transportation, because of placing the rack 5 of stem cell test tube hangs in 1 inside of box through four spring beams 4, can effectively cushion the stem cell test tube, prevent that the stem cell test tube from striking 1 inner wall of box and causing the damage.
A wireless temperature sensor 50 is fixedly installed inside the placing frame 5, a liquid nitrogen hopper 6 is fixedly clamped and connected to the inner side of the bottom of the heat-insulating layer 3, a liquid nitrogen replenisher 7 is fixedly installed on the upper surface of the bottom of the box body 1, and a safety valve 22 is fixedly installed at the top of the box cover 2; after stem cells are placed in a cell tube, the stem cells can be inserted into the placing frame 5 one by one, test tubes filled with the stem cells can be inserted into the test tube rack, the lamination is stacked in the placing frame 5, after the placement is completed, the box cover 2 is sealed AT the top of the box body 1, then, the temperature inside the box body 1 is detected in real time by the wireless temperature sensor 50, the wireless temperature sensor 50 selects the safety detection intelligent WX-AT01, when the temperature inside the box body 1 detected by the wireless temperature sensor 50 is higher than the preset temperature of the frozen storage of the stem cells, liquid nitrogen is filled into the box body 1 by starting the liquid nitrogen replenisher 7, the environment temperature inside the box body 1 is kept AT the optimum frozen storage temperature of the stem cells all the time, nitrogen is generated after the liquid nitrogen absorbs heat and is gasified, and the air pressure inside the box body 1 is regulated and controlled by the safety valve 22, so that the storage safety is ensured.
As shown in fig. 3-5, the liquid nitrogen replenisher 7 includes a fixing frame 70, a plurality of storage tanks 71 are fixedly mounted on the inner side of the fixing frame 70, and the adjacent storage tanks 71 are communicated, one end of one of the storage tanks 71 is communicated with a liquid nitrogen pump 72, the bottom of the fixing frame 70 is fixedly mounted on the inner wall of the bottom of the box body 1 through bolts, the output end of the liquid nitrogen pump 72 is communicated with an output pipe 73, the top of the output pipe 73 is fixedly inserted into one side of the liquid nitrogen bucket 6, and the liquid nitrogen pump 72 is used for delivering liquid nitrogen from the storage tanks 71 to replenish the liquid nitrogen into the liquid nitrogen bucket 6 to maintain the cryopreservation temperature of the stem cells in the box body 1.
As shown in fig. 3 and 4, a lithium battery 75 is electrically connected to one side of the liquid nitrogen pump 72, a starter 74 is fixedly mounted at the bottom of one side of the liquid nitrogen pump 72, the lithium battery 75 is used for supplying power to the liquid nitrogen pump 72, the starter 74 receives an instruction of the wireless temperature sensor 50 to control the start and stop of the liquid nitrogen pump 72, and when the wireless temperature sensor 50 detects that the temperature in the tank 1 is reduced, the starter 74 controls the liquid nitrogen pump 72 to supplement the amount of liquid nitrogen in the liquid nitrogen bucket 6.
As shown in fig. 3, a rotating shaft 23 is fixedly installed at the top of one side of the box body 1, the top of the rotating shaft 23 is rotatably connected with the bottom of one side of the box cover 2, and the box cover 2 rotates by using the rotating shaft 23 as a rotating shaft when deflecting, so as to realize the opening and closing of the box cover 2 to the top of the box body 1.
As shown in fig. 1 and 2, a handle 20 is fixedly mounted at the top of the box cover 2, a lock 21 is rotatably connected to the other side of the box cover 2, a stud 11 is fixedly mounted at the top of the other side of the box body 1, the handle 20 is convenient for a worker to take the device, and after the box cover 2 is tightly locked on the stud 11 through the lock 21, the box cover 2 and the box body 1 can be sealed.
As shown in fig. 1, a clamping groove 10 is integrally formed on the outer side of the box body 1, the outer side of the clamping groove 10 is made of transparent plastic, and stem cell information of a transportation batch can be marked on a card and placed in the clamping groove 10, so that a worker can distinguish the stem cell information.
The using method and the working principle of the device are as follows: after the stem cells are placed in the cell tubes, the stem cells can be inserted into the placing frame 5 one by one, or after test tubes filled with the stem cells are inserted into the test tube rack, the stem cells are stacked in the placing frame 5 in a laminated manner, and after the stem cells are placed, the box cover 2 is sealed at the top of the box body 1.
Then, the wireless temperature sensor 50 will detect the temperature inside the box 1 in real time, when the wireless temperature sensor 50 detects that the temperature inside the box 1 is higher than the preset temperature of stem cell cryopreservation, the liquid nitrogen pump 72 will be controlled to start working through the starter 74 for delivering the liquid nitrogen from the storage tank 71 to supplement the liquid nitrogen to the liquid nitrogen hopper 6, and the temperature of stem cell cryopreservation inside the box 1 is maintained, so that the ambient temperature inside the box 1 is always kept at the optimum cryopreservation temperature of the stem cells, nitrogen gas will be generated after the liquid nitrogen absorbs heat and gasifies, and the air pressure inside the box 1 will be regulated and controlled by the safety valve 22 to ensure the storage safety.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention in other forms, and any person skilled in the art may use the above-mentioned technical contents to change or modify the equivalent embodiment into equivalent changes and apply to other fields, but any simple modification, equivalent change and modification made to the above embodiments according to the technical matters of the present invention will still fall within the protection scope of the technical solution of the present invention.

Claims (7)

1. The utility model provides a cell collection transport case, includes box (1), case lid (2) and heat preservation (3), box (1) top one side and case lid (2) bottom one side swing joint, and the fixed joint in the outside of the inner wall of box (1) and heat preservation (3), its characterized in that: the even integrated into one piece in inboard top of box (1) has four lugs (12), every the bottom of lug (12) is all rotated and is connected with deflection head (40), and every deflection head (40) bottom equal joint has spring beam (4), the inside of heat preservation (3) has hung rack (5) through four spring beams (4), the inside fixed mounting of rack (5) has wireless temperature sensor (50), the inboard fixed joint in bottom of heat preservation (3) has liquid nitrogen fill (6), fixed surface installs liquid nitrogen replenisher (7) on box (1) bottom, the top fixed mounting of case lid (2) has relief valve (22).
2. A cell collection shipping cassette according to claim 1, wherein: the liquid nitrogen replenisher (7) comprises a fixing frame (70), a plurality of storage tanks (71) are fixedly mounted on the inner side of the fixing frame (70), adjacent storage tanks (71) are communicated, and one end of each storage tank (71) is communicated with a liquid nitrogen pump (72).
3. A cell collection shipping box according to claim 2, wherein: the bottom of the fixing frame (70) is fixedly installed on the inner wall of the bottom of the box body (1) through bolts, the output end of the liquid nitrogen pump (72) is communicated with an output pipe (73), and the top of the output pipe (73) is fixedly connected with one side of the liquid nitrogen bucket (6) in an inserting mode.
4. A cell collection shipping box according to claim 2, wherein: one side electric connection of liquid nitrogen pump (72) has lithium cell (75), and liquid nitrogen pump (72) one side bottom fixed mounting has starter (74).
5. A cell collection shipping cassette according to claim 1, wherein: a rotating shaft (23) is fixedly mounted at the top of one side of the box body (1), and the top of the rotating shaft (23) is rotatably connected with the bottom of one side of the box cover (2).
6. A cell collection shipping cassette according to claim 1, wherein: the top fixed mounting of case lid (2) has handle (20), and the opposite side of case lid (2) rotates and is connected with hasp (21), the opposite side top fixed mounting of box (1) has post (11).
7. A cell collection shipping cassette according to claim 1, wherein: the outer side of the box body (1) is integrally formed with a clamping groove (10).
CN202223230222.1U 2022-12-02 2022-12-02 Cell collection transport box Active CN218786218U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223230222.1U CN218786218U (en) 2022-12-02 2022-12-02 Cell collection transport box

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223230222.1U CN218786218U (en) 2022-12-02 2022-12-02 Cell collection transport box

Publications (1)

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CN218786218U true CN218786218U (en) 2023-04-04

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CN202223230222.1U Active CN218786218U (en) 2022-12-02 2022-12-02 Cell collection transport box

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117622711A (en) * 2023-12-18 2024-03-01 山东亿人生命科技有限公司 Collecting liquid storage device based on carbon dioxide fresh-keeping umbilical cord and placenta

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117622711A (en) * 2023-12-18 2024-03-01 山东亿人生命科技有限公司 Collecting liquid storage device based on carbon dioxide fresh-keeping umbilical cord and placenta
CN117622711B (en) * 2023-12-18 2024-05-17 山东亿人生命科技有限公司 Collecting liquid storage device based on carbon dioxide fresh-keeping umbilical cord and placenta

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