CN210642161U - Cell cryopreserving pipe shifts box - Google Patents
Cell cryopreserving pipe shifts box Download PDFInfo
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- CN210642161U CN210642161U CN201920860787.7U CN201920860787U CN210642161U CN 210642161 U CN210642161 U CN 210642161U CN 201920860787 U CN201920860787 U CN 201920860787U CN 210642161 U CN210642161 U CN 210642161U
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Abstract
The utility model discloses a cell cryopreserving pipe shifts box, a serial communication port, including lid, box body and cooling frame, the cooling frame is arranged in the box body, the cooling frame includes central cold source storehouse and a plurality of cell cryopreserving pipe storehouse, the cold source material has been placed in the central cold source storehouse, the lid is located on the box body, and make the airtight setting in central cold source storehouse. The central cold source bin is arranged in the center of the cooling frame, so that the storage space of the cold source substance is wide, the operation is convenient when the cold source substance is added, the operation difficulty is reduced, and the risk of frostbite caused by careless contact with the cold source substance is reduced; the cold source substance placed in the central cold source bin is preferably dry ice, the dry ice is used as the cold source substance, the refrigeration effect and the use safety can be considered, and meanwhile, liquid nitrogen or crushed ice can be used as necessary, so that the cold source substance is more convenient and flexible to select; the cooling frame is arranged in the box body, can be disassembled and is convenient to clean.
Description
Technical Field
The utility model relates to a cell cryopreserving recovery equipment technical field, concretely relates to cell cryopreserving pipe shifts box.
Background
The cell freezing tube is a common cell freezing container, and when the cells are thawed, the best operation is that the cell freezing tube just taken out from a liquid nitrogen tank or an ultra-low temperature refrigerator is quickly heated to more than 0 ℃ so as to quickly pass through-5 ℃ to 0 ℃ where the cells are most easily damaged, so that the cells are prevented from being damaged by the recrystallization of ice crystals and the death of the cells is avoided.
Taking out the cell cryopreservation tube from the liquid nitrogen tank or the ultra-low temperature refrigerator and then carrying the tube to a recovery operation table can consume a period of time, and in the transportation process, the cell cryopreservation tube needs to be kept in a low-temperature state. The utility model discloses consequently come for convenient short distance transport cell cryopreserving pipe under the low temperature freezing condition.
In the current cell freezing tube transfer device, for example: a low-temperature cell storage device convenient for transportation, application number 2018208795284, the utility model provides a low-temperature cell storage device convenient for transportation, which comprises a storage device body, a freezing tube transfer box and a detachable lifting rod; the interlayer of the shell of the cryopreservation tube transfer box is filled with liquid nitrogen, and the cell cryopreservation tube is placed inside the cryopreservation tube transfer box; the freezing storage pipe transfer box is arranged in the storage device body; the two sides of the storage device body are provided with first sunken parts, and the two sides of the freezing and storing pipe transfer box are provided with second sunken parts; the detachable lifting rod is provided with a connecting block, and the connecting block can be matched with the first concave part and the second concave part; the rod body of the detachable lifting rod can be stretched. The utility model discloses a freeze and deposit the pipe with the cell and directly place it shifts the box inside to freeze and deposit the pipe, places easily in disorder irregularity, influences the standardization of operation. The utility model discloses a shell interlayer packing that the pipe shifts the box is deposited in freezing has the liquid nitrogen, can not use dry ice or garrulous ice as the cold source material, and in the in-service operation use, it is an extremely dangerous operation to use the liquid nitrogen to fill the shell interlayer as the cold source material, can't empty absolutely in the transportation, in case the operation has the mistake, causes the incident very easily, and the danger coefficient is high.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a cell cryopreserving pipe shifts box solves one or more among the above-mentioned prior art problem.
According to the utility model discloses a cell cryopreserving pipe shifts box, a serial communication port, including lid, box body and cooling frame, the cooling frame is arranged in the box body, the cooling frame includes central cold source storehouse and a plurality of cell cryopreserving pipe storehouse, central cold source storehouse is located the center of cooling frame, the cold source material has been placed in the central cold source storehouse the lid is located on the box body, and makes central cold source storehouse is airtight to be set up.
In some embodiments, the central cold source bin may be provided with a central cold source bin cover, the central cold source bin cover is disposed inside the box body and covers the central cold source bin, and the central cold source bin cover may be provided with a lifting ring.
In some embodiments, the shape of the cell cryopreservation tube transfer box can be cylindrical, cubic, rectangular or polygonal, the cooling rack can be cylindrical, cubic, rectangular or polygonal, the central cold source bin can be cylindrical, cubic, rectangular or polygonal, and the vertical projection of the central cold source bin cover is circular, square, rectangular or polygonal.
In some embodiments, the whole appearance of cell cryopreserving pipe transfer box the cooling frame with central authorities 'cold source storehouse is the cylinder, central authorities' cold source storehouse is located the center of cylinder cooling frame, the other serial number that is equipped with in bin mouth of cell cryopreserving pipe storehouse, cell cryopreserving pipe storehouse figure is 2 ~ 30, radiation symmetric distribution in around the central authorities 'cold source storehouse, central authorities' cold source storehouse degree of depth is 20 ~ 150mm, and the diameter is 30 ~ 100mm, cell cryopreserving pipe storehouse is the cylinder, and the degree of depth is 20 ~ 150mm, the diameter is 8 ~ 15 mm.
In some embodiments, the whole appearance of cell cryopreservation pipe transfer box, the cooling frame with central cold source storehouse is the cuboid shape, central cold source storehouse is located the center of cuboid shape cooling frame, the other serial number that is equipped with of door of cell cryopreservation pipe storehouse, cell cryopreservation pipe storehouse number is 2 ~ 30, divide into 2n (n is the positive integer of 1 to 3) row, bilateral symmetry distributes in the both sides of central cold source storehouse major axis direction, central cold source storehouse degree of depth is 20 ~ 150mm, and length is 50 ~ 500mm, and the width is 20 ~ 80mm, cell cryopreservation pipe storehouse is the cylinder, and the degree of depth is 20 ~ 150mm, and the diameter is 8 ~ 15 mm.
In some embodiments, the box cover, the box body and the central cool source compartment cover are made of a heat insulating material, and the heat insulating material is made of an organic material. Preferably, it is a crosslinked polyethylene foam.
In some embodiments, the cooling rack is made of a metal having excellent thermal conductivity. Preferably, the metal is aluminum or aluminum alloy.
In some embodiments, the cold source substance comprises dry ice, liquid nitrogen, or crushed ice. Preferably, dry ice.
The utility model has the advantages that:
1. the central cold source bin is arranged in the center of the cooling frame, so that the storage space of the cold source substance is wide, the operation is convenient when the cold source substance is added, the operation difficulty is reduced, and the risk of frostbite caused by careless contact with the cold source substance is reduced;
2. the cold source substance is placed in the central cold source bin, so that the cold source substance cannot directly contact the box body material to gradually dissipate cold energy, the cold energy retention time is longer, and the cold energy utilization rate is higher;
3. the central cold source bin is positioned in the center of the cooling rack, and after cold source substances are placed, the cold energy balance of the cooling rack is quicker and more uniform;
4. the cell freezing pipe bins are regularly arranged around or at two sides of the central cold source bin, each cell freezing pipe bin is provided with a serial number, the distances from the cell freezing pipe bins to the central cold source bin are the same, and only one cell freezing pipe can be placed in each cell freezing pipe bin, so that the cell freezing pipes are regularly placed, and the standard operation is facilitated;
5. the cold source substance placed in the central cold source bin is preferably dry ice, the dry ice is used as the cold source substance, the refrigeration effect and the use safety can be considered, and meanwhile, liquid nitrogen or crushed ice can be used as necessary, so that the cold source substance is more convenient and flexible to select;
6. the cell freezing tube transfer box of the utility model can maintain the cell freezing tube at-78.5 ℃ for more than one hour, and is matched with the Siemens series anhydrous dry resuscitation equipment, thereby facilitating the resuscitation of a plurality of cell freezing tubes without frequently taking the cell freezing tubes out of the low-temperature preservation equipment;
7. the cooling frame is arranged in the box body, can be disassembled and is convenient to clean.
Drawings
Fig. 1 is a schematic structural diagram of a cell cryopreservation tube transfer box according to an embodiment of the present invention;
fig. 2 is a top view of fig. 1 of the present invention;
FIG. 3 is a schematic structural view of a cell cryopreservation tube transfer box according to a second embodiment of the present invention;
FIG. 4 is a schematic structural view of a cell cryopreservation tube transfer box according to a third embodiment of the present invention;
FIG. 5 is a schematic structural view of a cell cryopreservation tube transfer cassette according to a fourth embodiment of the present invention;
FIG. 6 is a schematic structural diagram of a box body and a cooling rack of a cell cryopreservation tube transfer box according to a fifth embodiment of the present invention;
FIG. 7 is a top view of the heat source capsule of FIG. 6;
FIG. 8 is a side view of the cold source capsule of FIG. 6;
FIG. 9 is a top view of the cassette, cooling rack and lid of the cold source compartment of FIG. 6;
fig. 10 is a side view of the lid of fig. 6;
FIG. 11 is a side view of the cartridge, the cooling rack, and the cold source compartment cover of FIG. 6;
FIG. 12 is a side view of the case body, cooling rack, cold source housing cover, and case cover of FIG. 6.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings.
As shown in figure 1, a cell cryopreserving pipe shifts box, including lid 1, box body 2 and cooling frame 3, cooling frame 3 settles in box body 1, and cooling frame 3 includes central cold source storehouse 31 and a plurality of cell cryopreserving pipe storehouse 32, has placed the dry ice refrigeration source in the central cold source storehouse 31, and the other serial number that is equipped with in the bin mouth of cell cryopreserving pipe storehouse 32, lid 1 lid is located on box body 2 to make central cold source storehouse 31 airtight setting.
The central cold source chamber 31 is provided with a central cold source chamber cover 4, and the central cold source chamber cover 4 may or may not be provided with a lifting ring 41.
The utility model provides a cell cryopreserving pipe shifts box, provides safe, convenient transportation mode to the cell cryopreserving pipe sample of preserving at liquid nitrogen container or ultra-low temperature refrigerator before recovery, puts some dry ice in the central cold source storehouse of cooling rack before using, covers central cold source storehouse lid, makes the temperature of whole cooling rack equilibrate the temperature to the dry ice fast. The cell cryopreservation tube is taken out of the preservation device, numbered correspondingly, and immediately placed in a cell cryopreservation tube bin of the cooling frame, the box cover is covered, so that the cell cryopreservation tube sample can be maintained at-78.5 ℃ for a long time, and then the cell cryopreservation tube sample can be taken to the recovery device for recovery, so that the low-temperature state of the cell cryopreservation tube sample in the transfer process can be better ensured, and the cell recovery efficiency can be improved. If necessary, on the premise of ensuring safety, liquid nitrogen can be placed in the central cold source bin in advance to serve as a refrigerating source.
Dry ice is a solid state of carbon dioxide and is often used to keep objects in a frozen or cryogenic state because it is very cold, at a temperature of-78.5 ℃. Although both dry ice and liquid nitrogen are cryogenic substances, the use of dry ice is much safer than the use of liquid nitrogen.
Example 1:
as shown in figures 1-2, the whole appearance of the cell cryopreservation tube transfer box, the cooling frame 3 and the central cold source bin 31 are all cylindrical, the central cold source bin 31 is positioned at the center of the cooling frame 3, the number of the cell cryopreservation tube bins 32 is 2-30, the cell cryopreservation tube bins are symmetrically distributed around the central cold source bin 31 in a radiation mode, numbers are arranged beside bin mouths of the cell cryopreservation tube bins 32, the depth of the central cold source bin 31 is 20-150 mm, the diameter of the central cold source bin is 30-100 mm, the cell cryopreservation tube bins 32 are cylindrical, the depth of the central cold source bin is 20-150 mm, and the diameter of the central cold source bin is 8-15 mm.
Example 1 no central cold source compartment cover.
Can be used to transport or keep in the volume and be less than 2ml cell cryopreserving pipe, the structure is: 1. a box cover; 2. a box body; 3. a cooling rack; 31. a central cold source bin; 32. and (5) freezing and storing the cell in a tube bin.
Example 2:
as shown in figure 3, the whole appearance of the cell cryopreservation tube transfer box, the cooling frame 3 and the central cold source bin 31 are cylindrical, the central cold source bin 31 is located at the center of the cooling frame 3, the number of the cell cryopreservation tube bins 32 is 2-30, the cell cryopreservation tube bins 32 are symmetrically distributed around the central cold source bin 31 in a radiation mode, numbers are arranged beside bin openings of the cell cryopreservation tube bins 32, the depth of the central cold source bin 31 is 20-150 mm, the diameter of the central cold source bin is 30-100 mm, the cell cryopreservation tube bins 32 are cylindrical, the depth of the central cold source bin is 20-150 mm, and the diameter of the central cold source bin is 8-15 mm.
Can be used to transport or keep in the volume and be less than 2ml cell cryopreserving pipe, the structure is: 1. a box cover; 2. a box body; 3. a cooling rack; 31. a central cold source bin; 32. freezing and storing the cells in a tube bin; 4. a central cold source bin cover.
Example 3:
as shown in FIG. 4, the device can be used for the transportation of 5ml cell freezing tubes, the basic structure is the same as that of example 1, and the depth of the cell freezing tube bin 32 is greater than that of the cell freezing tube bin 32 in example 1, so that the device can be used for the transportation of 5ml cell freezing tubes.
Example 4:
as shown in FIG. 5, the device can be used in a 5ml cell freezing tube, and the basic structure is the same as that of example 2.
The cell cryopreservation tube transfer box can also be designed into a cell cryopreservation tube transfer box for transferring cell cryopreservation tubes with different sizes according to actual needs.
Example 5:
as shown in the figures 6-12, the whole appearance of the cell cryopreservation tube transfer box, the cooling frame 3 and the central cold source bin 31 are cuboid, the central cold source bin 31 is positioned at the center of the cooling frame 3, the number of the cell cryopreservation tube bins 32 is 2-30, the cell cryopreservation tube bins are divided into a positive integer array with 2nn from 1 to 3, the cell cryopreservation tube bins are bilaterally and symmetrically distributed at two sides of the long axis direction of the central cold source bin 31, numbers are arranged beside bin openings of the cell cryopreservation tube bins 32, the depth of the central cold source bin 31 is 20-150 mm, the length of the central cold source bin is 50-500 mm, the width of the central cold source bin is 20-80 mm, the cell cryopreservation tube bins 32 are cylindrical, the depth of the central cold source bin is 20-.
The using method comprises the following steps:
the invention relates to a cell cryopreservation tube transfer box, which is a short-distance and short-time transportation solution of a portable cell cryopreservation tube, is used for processing and transporting the cell cryopreservation tube, and is used for recovering from long-term storage in a liquid nitrogen tank or an ultralow temperature refrigerator to use a cell cryopreservation tube dry-type recovery instrument. Before using the cell freezing tube transfer box, dry ice is added into the central cold source bin, and the cell freezing tube transfer box is kept still for about 10 minutes, so that the cooling rack is balanced to the temperature of the dry ice. The frozen cell freezing tube is extracted from a liquid nitrogen tank or an ultra-low temperature refrigerator, is correspondingly numbered and is quickly placed into a cell freezing tube bin of a cooling frame, the design purpose of the cell freezing tube transfer box is to keep the sample temperature at about-78.5 ℃, and the low-temperature state of one hour can be kept by covering a box cover. The cell cryovial may then be transported to a cell cryovial dry resuscitation apparatus for subsequent anhydrous dry resuscitation of the cell cryovial.
The utility model has the advantages that:
1. the central cold source bin is arranged in the center of the cooling frame, so that the storage space of the cold source substance is wide, the operation is convenient when the cold source substance is added, the operation difficulty is reduced, and the risk of frostbite caused by careless contact with the cold source substance is reduced;
2. the cold source substance is placed in the central cold source bin, so that the cold source substance cannot directly contact the box body material to gradually dissipate cold energy, the cold energy retention time is longer, and the cold energy utilization rate is higher;
3. the central cold source bin is positioned in the center of the cooling rack, and after cold source substances are placed, the cold energy balance of the cooling rack is quicker and more uniform;
4. the cell freezing pipe bins are regularly arranged around or at two sides of the central cold source bin, each cell freezing pipe bin is provided with a serial number, the distances from the cell freezing pipe bins to the central cold source bin are the same, and only one cell freezing pipe can be placed in each cell freezing pipe bin, so that the cell freezing pipes are regularly placed, and the standard operation is facilitated;
5. the cold source substance placed in the central cold source bin is preferably dry ice, the dry ice is used as the cold source substance, the refrigeration effect and the use safety can be considered, and meanwhile, liquid nitrogen or crushed ice can be used as necessary, so that the cold source substance is more convenient and flexible to select;
6. the cell freezing tube transfer box of the utility model can maintain the cell freezing tube at-78.5 ℃ for more than one hour, and is matched with the Siemens series anhydrous dry resuscitation equipment, thereby facilitating the resuscitation of a plurality of cell freezing tubes without frequently taking the cell freezing tubes out of the low-temperature preservation equipment;
7. the cooling frame is arranged in the box body, can be disassembled and is convenient to clean.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, similar modifications and improvements can be made without departing from the inventive concept of the present invention, and these are also considered to be within the protection of the present invention.
Claims (8)
1. The utility model provides a cell cryopreserved pipe shifts box, its characterized in that, includes lid (1), box body (2) and cooling frame (3), cooling frame (3) are arranged in box body (2), cooling frame (3) are including central cold source storehouse (31) and a plurality of cell cryopreserved pipe storehouse (32), central cold source storehouse (31) are located the center of cooling frame (3), cold source material has been placed in central cold source storehouse (31), lid (1) lid is located on box body (2), and make central cold source storehouse (31) airtight setting.
2. The cell cryopreservation tube transferring box of claim 1, wherein the central cold source bin (31) is provided with a central cold source bin cover (4), the central cold source bin cover (4) is arranged in the box body (2) and covers the central cold source bin (31), and the central cold source bin cover (4) is provided with a lifting ring (41).
3. The cell cryopreservation tube transferring box as claimed in claim 2, wherein the shape of the cell cryopreservation tube transferring box is cylindrical, cubic, rectangular or polygonal, the cooling rack (3) is cylindrical, cubic, rectangular or polygonal, the central cold source bin (31) is cylindrical, cubic, rectangular or polygonal, and the vertical projection of the central cold source bin cover (4) is circular, square, rectangular or polygonal.
4. The cell cryopreservation tube transferring box of claim 3, wherein the overall shape of the cell cryopreservation tube transferring box, the cooling rack (3) and the central cold source bin (31) are cylindrical, the central cold source bin (31) is positioned in the center of the cylindrical cooling rack (3), serial numbers are arranged beside the bin opening of the cell cryopreservation tube bin (32), the number of the cell cryopreservation tube bins (32) is 2-30, the cell cryopreservation tube bins are radially and symmetrically distributed around the central cold source bin (31), the depth of the central cold source bin (31) is 20-150 mm, the diameter of the central cold source bin is 30-100 mm, and the cell cryopreservation tube bin (32) is cylindrical, the depth of the central cold source bin is 20-150 mm, and the diameter of the central cold source bin is 8-15 mm.
5. The cell freezing tube transfer box according to claim 3, wherein the overall shape of the cell freezing tube transfer box, the cooling rack (3) and the central cooling source bin (31) are cuboid, the central cooling source bin (31) is located in the center of the cuboid cooling rack (3), serial numbers are arranged beside the bin opening of the cell freezing tube bin (32), the number of the cell freezing tube bin (32) is 2-30, the cell freezing tube bin is divided into 2n rows, n is a positive integer from 1 to 3, the cell freezing tube bin is bilaterally symmetrically distributed on two sides of the long axis direction of the central cooling source bin (31), the depth of the central cooling source bin (31) is 20-150 mm, the length is 50-500 mm, the width is 20-80 mm, the cell freezing tube bin (32) is cylindrical, the depth is 20-150 mm, and the diameter is 8-15 mm.
6. The cell freezing tube transfer box according to claim 2, wherein: the box cover (1), the box body (2) and the central cold source bin cover (4) are all made of heat-insulating materials, and the heat-insulating materials are made of organic materials.
7. The cell cryopreservation tube transfer box of claim 1, wherein: the cooling frame (3) is made of metal with excellent heat-conducting property.
8. The cell cryopreservation tube transfer box of claim 1, wherein: the cold source substance comprises dry ice, liquid nitrogen or crushed ice.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920860787.7U CN210642161U (en) | 2019-06-06 | 2019-06-06 | Cell cryopreserving pipe shifts box |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920860787.7U CN210642161U (en) | 2019-06-06 | 2019-06-06 | Cell cryopreserving pipe shifts box |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210642161U true CN210642161U (en) | 2020-06-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920860787.7U Active CN210642161U (en) | 2019-06-06 | 2019-06-06 | Cell cryopreserving pipe shifts box |
Country Status (1)
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|---|---|
| CN (1) | CN210642161U (en) |
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2019
- 2019-06-06 CN CN201920860787.7U patent/CN210642161U/en active Active
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