CN209590044U - High-efficiency chemiluminescence immunoassay analyzer - Google Patents
High-efficiency chemiluminescence immunoassay analyzer Download PDFInfo
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- CN209590044U CN209590044U CN201920231908.1U CN201920231908U CN209590044U CN 209590044 U CN209590044 U CN 209590044U CN 201920231908 U CN201920231908 U CN 201920231908U CN 209590044 U CN209590044 U CN 209590044U
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- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The utility model discloses a high-efficiency chemiluminescence immunoassay analyzer, which comprises a frame with a frame structure, wherein an upper platform and a lower platform are arranged on the frame, a reaction cup bin system and an incubation system are sequentially arranged on the upper platform along the length direction of the upper platform, the reaction cup bin system is close to one corner of the upper platform, a filling system is arranged on one side of the reaction cup bin system, a washing system is arranged on one side of the incubation system, a detection system is arranged on one end of the upper platform, which is far away from the reaction cup bin system, and a gripper system is erected above the upper platform by the frame; and a sample supply system and a reagent bin storage system are arranged on the lower platform at positions close to the end part, and the reagent bin storage system is positioned on the filling system. Retrench each system architecture, realize that the function integrates, improve detection efficiency, rationally arrange simultaneously in the frame, make full use of high space reduces whole occupation volume, optimizes system such as washing, mixing and detection very much, improves and detects structure precision and fail safe nature greatly.
Description
Technical field
The utility model relates to Medical Equipment fields, and in particular to a kind of efficient chemical luminescence immunoassay instrument.
Background technique
In immunoassay experiment, generallys use chemiluminescence immune analysis method and body fluid is tested and analyzed, existing inspection
During survey, experimenter needs to contain body fluid to be detected using dedicated reaction cup, and uses magnetic particle immunoassay
Method, it will usually by filling, mix, be incubated for, washing and detection and etc., wherein magnetic particle refer to magnetic nano-particle with
Inorganic or organic molecule combines the colloidal state composite material being dispersed in certain base fluid with high stability formed, magnetic
Particle immunoassay refers to the surface that the bioactive substances such as enzyme, antibody, oligonucleotides are fixed on to magnetic particle by magnetic particle,
Then various active detection is carried out.Because entire detection process step is relatively more, therefore it is more to use system authority, especially
It is related to the mechanisms such as transhipment, washing, testing agency, this results in existing immunity analysis instrument structure is complicated cumbersome, and volume is larger,
And washing system detersive efficiency is low.
Utility model content
In order to solve the above technical problems, the utility model provides a kind of efficient chemical luminescence immunoassay instrument, is reducing
Under the premise of existing immunity analysis instrument volume, reasonable Arrangement optimizes each system structure, and mechanism is avoided to repeat to be arranged, and improves detection effect
Rate and precision.
To achieve the above object, technical solutions of the utility model are as follows:
A kind of efficient chemical luminescence immunoassay instrument, it is critical that including the rack in frame structure, which has
Upper mounting plate and lower platform are successively arranged reaction cup storehouse system and incubation system on the upper mounting plate along its length, and react
Cup storehouse system is close to one jiao of upper mounting plate, and the side of reaction cup storehouse system is equipped with loading system, and the side of incubation system is set
There is washing system, one end far from reaction cup storehouse system is equipped with detection system on upper mounting plate, and the rack is in the top of upper mounting plate
It is provided with handgrip system；
It is equipped with sample-feed system and reagent storage system by the position of close end on the lower platform, and the reagent is deposited
Storage system is located at immediately below loading system, and wherein reaction cup storehouse system is used for for storing supply response cup, loading system to anti-
It answers and sample, reagent and magnetic particle liquid is added in cup to form mixed solution, handgrip system is for reaction cup between each system
Movement, washing system be used for solution in reaction cup carry out washing substrate filling and mix operate.
Instrument compactedness is improved, is conducive to contract by the position of each system of reasonable Arrangement on the rack using above scheme
Subtract overall volume, optimization system equipment, simplified system component realizes that function is integrated, to improve instrumental detection efficiency and essence
Degree.
As preferred: being coated with shell in the rack, the position that reaction cup storehouse system is corresponded on the shell offers
Cup holder is put into mouth, and the position of corresponding sample-feed system offers sample and is put into mouth, and corresponding reagent storage system is provided with reagent
It is put into mouth, frame top is provided with surge flask storehouse；
Waste port is additionally provided on the upper mounting plate, the position of face waste port is equipped with waste bin, the shell on lower platform
The position of upper corresponding waste bin is equipped with waste material outlet, and the rack is equipped with temperature adjusting mechanism.Using above scheme, can make
Instrument detection process is in the environment of relative closure, and reducing environmental factor such as dust temperature etc. influences, and is conducive to further mention
High measurement accuracy, while by way of opening up window, convenient for carrying out operation and the fixation of surge flask etc. in outside, improve instrument
Device operability.
As preferred: the washing system includes substrate, mixes pedestal, washing cup holder, mixes component and washing head, wherein
Substrate is fixedly arranged on upper mounting plate, mix base runner be set on substrate, and can opposing substrate sliding, have on sliding stroke
Dress takes, substrate fills and three positions of washing；
Wherein washing cup holder and mixing component are all set in and mix on pedestal, and washing cup holder, which has, to be distributed along its length
Washing hole, mix component for making and wash cup holder reciprocally swinging in horizontal plane, will be in the washing hole in reaction cup
Liquid blending, washing head are movably set on substrate, and can be moved up and down with respect to upper mounting plate, and washing head has and washing hole one
One corresponding washing needle group and at least one substrate fill needle, and when mixing pedestal is in washing location, washing needle group is located at
Right above washing hole, when in substrate filling position, substrate filling needle is located at the surface of washing hole.
Using above scheme, by the washing pedestal of sliding setting, satisfaction takes the dress of reaction cup, washs, substrate fills
Basic function demand, while will directly mix function and be combined in washing associated components, without a mixing work is still further arranged
Position advantageously reduces space hold and handgrip operating number, improves the micromation hair that detection efficiency is advantageously implemented instrument simultaneously
Exhibition.
As preferred: the lower section for mixing pedestal and being located at substrate, the corresponding position for mixing pedestal both ends of base plate bottom are set
Have and mix pedestal sliding rail, described mix has the mixing pedestal sliding block cooperated with its sliding rail, the mixing pedestal on pedestal sliding rail
Both ends are fixedly connected with corresponding mixing pedestal sliding block respectively；
The substrate is equipped with for driving mixing pedestal right along the driving motor A for mixing the sliding of pedestal sliding rail, substrate
The sliding stroke that pedestal should be mixed is equipped with installing port, and the position that upper mounting plate corresponds to installing port has through-hole.It is convenient for by installing port
The assembling of raising system prevents from generating interference in washing pedestal sliding process, while by installation double sided slider bar, can make to wash bottom
Seat sliding stability more preferably, prevents solution from splashing out.
As preferred: the washing head is equipped with anti-tie cup mechanism, and the anti-tie cup mechanism in washing head for declining
Whether monitoring washing needle group and substrate filling needle are touched with reaction cup in journey.Needle is washed by the fast slowdown monitoring of anti-tie cup mechanism
Whether group and substrate filling needle are touched with reaction cup, and then feedback information avoids movement machine to corresponding measure is made from the background
Structure repeats mechanical action, i.e. washing head moves always downward, causes to wash needle group or substrate filling needle damage, and then cause other
Failure reduces detection efficiency.
As preferred: the detection system includes camera bellows cabinet and testing agency, is equipped with darkroom, detection machine in camera bellows cabinet
Structure is fixedly arranged on camera bellows cabinet, the inlet and outlet being connected to darkroom is offered on the side wall of camera bellows cabinet, testing agency is for detecting
In darkroom in reaction cup liquid luminous quantity；
The camera bellows cabinet, which is equipped with, reacts cup holder with what it was slidably matched, which is equipped with setting for upper lower open mouth
Cup slot, and react cup holder can the sliding of relatively dark box body to open or close inlet and outlet, when import and export open when, set glass slot and expose
Outside darkroom, when importing and exporting closing, sets glass slot and be in darkroom.
Using above scheme, detects camera bellows and take independent opening structure, the i.e. load by reaction cup holder as reaction cup
Body, while shading is sealed to darkroom by reaction cup holder, for opposite existing structure, in dark indoor reaction in this programme
Cup not will receive the influence of handgrip negative pressure, and handgrip negative pressure suction nozzle will not be influenced by liquid, and corresponding substrate fills will not be by
Negative pressure influences, it is ensured that the accuracy of substrate adding amount is conducive to the reliability for improving testing result and handgrip movement.
As preferred: the corresponding position for setting glass slot has in step-like detection boss, the detection on the reaction cup holder
The lower end of boss has the anti-tampering magnet along reaction cup holder thickness direction setting, and the anti-tampering magnet is located remotely from detection machine
The side of structure.For certain reaction systems, using above scheme, in the detection process, magnet can be installed on reaction cup holder, lead to
It crosses magnet and the magnetic particle in solution in reaction cup is adsorbed to the side far from lamp guide, to avoid magnetic particle in the solution
Suspension is blocked, and testing result is influenced, and improves detection accuracy.
As preferred: reaction cup storehouse system includes cup orlop seat and cup holder, and the cup orlop seat is equipped at least one
It is a for placing the accommodation groove of cup holder, the accommodation groove open topped is distributed with for upright placing response cup on the cup holder
Accommodating hole, the accommodating hole is vertically arranged, and the bottom of the cup orlop seat is equipped with heating device A, and cup orlop seat is equipped with temperature
Spend sensors A.Using above scheme, reduce the mechanisms such as row's cup transhipment of existing equipment, by cup holder by the anti-of marshalling
It answers cup to be directly placed into glass storehouse to use, reduces analyzer overall volume, while pre- heat effect can be carried out to the reaction cup being put into, this
Sample can subsequent filling sample from the influence of temperature, opposite temperature constant state is at, to improve detection accuracy.
As preferred: the handgrip system includes guide rail bracket and two handgrip mechanisms, and wherein guide rail bracket includes X direction guiding rail, Y
Direction guiding rail and Z-direction guide rail, the handgrip mechanism include handgrip seat, and the handgrip seat can be along guide X under the driving of driving mechanism
Rail, Y-direction guide rail and Z-direction guide rail carry out three-dimensional sliding, and handgrip seat bottom is equipped with suction nozzle, and the lower end of the suction nozzle is bonded
There is rubber, the suction nozzle is connected with positive pressure source and negative pressure source by pipeline, or is connected to air pump by pipeline.Pass through two handgrips
Mechanism is to meet the station demand of entire analyzer, improves space utilization rate and handgrip mechanism spits a glass suction cup reliability, be conducive to
The detection efficiency of analyzer is improved, while the damage to reaction cup is avoided by rubber.
As preferred: the agent bin storage system includes agent bin, and at least two and its are equipped at the top of the agent bin
The lower pinhole of inside connection, the agent bin top are equipped with the dilution bottle fixing seat being connected to agent bin inside, the dilution bottle
Fixing seat is for placing dilution bottle.Dilution bottle is protected by means of the cooling capacity that semiconductor chilling plate in agent bin generates
Temperature prevents dilution temperature from changing with variation of ambient temperature, and reduction has an impact experiment, is conducive to improve testing result
Precision.
Compared with prior art, the utility model has the beneficial effects that
Using the efficient chemical luminescence immunoassay instrument of above technical scheme, each system structure is simplified, realizes that function is integrated
Change, improve detection efficiency, while carrying out reasonable Arrangement on the rack, make full use of height space, reduces whole occupancy volume, it is special
The systems such as You Hua it not wash, mix and detect, greatly improve detection structure precision and security reliability.
Detailed description of the invention
FIG. 1 is a schematic structural view of the utility model；
Fig. 2 is the schematic diagram of internal structure of Fig. 1；
Fig. 3 is upper mounting plate top view；
Fig. 4 is lower platform top view；
Fig. 5 is reaction cup storehouse system structure diagram；
Fig. 6 is agent bin memory system architecture schematic diagram；
Fig. 7 is washing system structural schematic diagram；
Fig. 8 is the rear structure schematic diagram of Fig. 7；
Fig. 9 is the bottom substance schematic diagram of Fig. 7；
Figure 10 is washing head structural schematic diagram；
Figure 11 is to mix component structure diagram；
Figure 12 is the cross-sectional view of Figure 11；
Figure 13 is to mix pedestal to be in the structural schematic diagram filled when fetch bit is set；
Figure 14 is the structural schematic diagram mixed when pedestal is in substrate filling position；
Figure 15 is anti-tie cup mechanism scheme of installation；
Figure 16 is the cross-sectional view of Figure 15；
Figure 17 is detection system structure；
Figure 18 is reaction cup seat structure schematic diagram；
Figure 19 is the cross-sectional view of Figure 18；
Figure 20 is handgrip system structure diagram；
Figure 21 is the other side Figure 20 structural schematic diagram；
Figure 22 is that a kind of suction nozzle pipeline connects embodiment schematic diagram.
Specific embodiment
The utility model is described in further detail with attached drawing with reference to embodiments.
It mainly include substantially being in referring to figs. 1 to the efficient chemical luminescence immunoassay instrument of the utility model shown in Figure 22
The rack 100 of rectangular frame structure is successively arranged upper mounting plate 110 and lower platform along its short transverse in rack 100 from top to bottom
120, the two is horizontally disposed, is successively arranged reaction cup storehouse system 400 and incubation system on upper mounting plate 110 along its length
600, and reaction cup storehouse system 400 is set on one jiao of upper mounting plate 110, upper mounting plate 110 in the side of reaction cup storehouse system 400
There is loading system 500, is similarly equipped with washing system 700 in the side of incubation system 600, and far from reaction on upper mounting plate 110
One end of cup storehouse system 400 is equipped with detection system 800 close to the position of washing system 700, in upper mounting plate 110 in rack 100
Top is provided with handgrip system 900, and the top of rack 100 is additionally provided with surge flask storehouse 180, for placing buffer bottle.
Sample-feed system 200 and agent bin storage system 400, and sample are equipped with by the position of close end on lower platform 120
This feed system 200 is generally within the underface of reaction cup storehouse system 400, and agent bin storage system 400 is generally within filling system
The underface of system 500, while for convenience of the centralized processing of reaction cup, therefore waste port 112, waste port are equipped on upper mounting plate 110
112 are located remotely from one end of reaction cup storehouse system 400, and the position of face waste port 112 is removably equipped with useless on lower platform 120
Feed bin 121, waste bin 121 are fixed on lower platform 120 by sliding bottom, and sliding bottom is slidably matched with lower platform 120.
Transshipment acitivity 140 is additionally provided on upper mounting plate 110, transshipment acitivity 140 is set substantially along the length direction of upper mounting plate 110
It sets, and part is located at incubation system 600 there are also part and washing is between reaction cup storehouse system 400 and loading system 500
System 700, is mainly used for temporary placing response cup, and be moved to the station of needs, plays transfer.
The structure of each system or mechanism is specific as follows, and with reference to Fig. 3 and Fig. 5, reaction cup storehouse system 400 includes cup orlop seat
410 and cup holder 420, and there is heating and heat preserving function, wherein cup orlop seat 410 is fixedly connected with upper mounting plate 110, cup orlop seat
410, which are equipped at least one, is used to place accommodation groove of cup holder 420, accommodation groove open topped, is distributed on cup holder 420 for just
The accommodating hole for setting reaction cup is stood up, accommodating hole is vertically arranged, and the bottom of cup orlop seat 410 is equipped with heating device A, cup orlop seat
410 are equipped with temperature sensor A, and cup holder 420 is for temporarily storing reaction cup.
With reference to Fig. 3, loading system 500 mainly includes that sample filling mechanism 510, dilution mechanism 520 and reagent fill mechanism
530, three is arranged along the width direction of upper mounting plate 110, and is sequentially distributed along the length direction of upper mounting plate 110, wherein sample
Mechanism 510 is filled close to one end where reaction cup storehouse system 400, sample filling mechanism 510 is mainly used for carrying out adding for sample
Note, dilution mechanism 520 be then mainly used for it is necessary to when complete paired samples dilution, reagent filling mechanism 530 is mainly used for
Carry out the filling of reagent and magnetic particle liquid.Sample, which fills mechanism 510, has dilution with sample filling needle, dilution mechanism 520
Needle group, reagent fill mechanism 530 have reagent fill needle, three be respectively used to from lower platform 120 draw sample, dilution and
In different reagent injection reaction cups.
Agent bin storage system 300 generally within loading system 500 underface, as shown, agent bin storage system
300 general structures are similar to tradition, mainly include the agent bin 310 in hollow columnar structures, must be equipped with surely with inside it
The lower pinhole 311 of connection is provided with reagent disc in agent bin 310 in a rotatable manner, and reagent disc is for placing kit, reagent
Storehouse 310 is equipped with the refrigerating plant of external, in the present embodiment, is additionally provided at the top of agent bin 310 and its internal dilution bottle being connected to
Fixing seat 320, dilution bottle fixing seat 320 is for placing dilution bottle 321, thus by the cold temperature realization pair in 310 inside of agent bin
The cryo-conservation of dilution reduces influence of the temperature to detection.Incubation system 600 in the present embodiment has the heating of ground pit type
Heat insulation effect, sufficiently simulation human body environment, weaken the influence of environment temperature significantly.
With reference to Fig. 3, Fig. 7 to Figure 16, washing system 700 mainly includes the substrate 710 in rectangular plate-like structure in the application,
And it is movably set in the mixing pedestal 720 on substrate 710, substrate 710 is fixedly arranged on upper mounting plate 120, in the application, mixes base
Seat 720 can 710 linear slide of opposing substrate, and on its sliding stroke have dress fetch bit set, substrate filling position and washing position
It sets, and mixes pedestal 720 in sliding process, corresponding position, waiting or the process for completing corresponding position can be rested on.
It mixes and is installed with washing cup holder 730 on pedestal 720, wash and washing hole 731, washing hole 731 is distributed on cup holder 730
It is mainly used for placing response cup, and ensures stability of the reaction cup in washing hole 731, washing hole 731 is along washing cup holder 730
Length direction distribution, in the actual production process, it is not limited to which lineal layout according to instrument size and can need to carry out square matrix
Distribution or curve distribution, are equipped with washing head 750 above substrate 710, washing head 750 can opposing substrate 710 move up and down,
And have and wash needle group 751 and at least one substrate filling needle 752 correspondingly with washing hole, each washing in the application
Needle group 751 includes an aspiration needle and a filling needle.
When mixing pedestal 720 is in washing location, the washing hole 731 below the just face of needle group 751 is washed, mixing is worked as
When pedestal 720 is in substrate filling position, substrate fills the surface that needle 752 is then in washing hole 731.
Secondly, mixing component 740 mixing to be provided between pedestal 720 and washing cup holder 730, mixing component 740 can band
Dynamic washing cup holder 730 is swung back and forth horizontally, thus reach to the mixing in reaction cup solution in washing hole 731, the application's
It mixes component 740 to be mainly used for mixing in washing process, comes into full contact with cleaning solution with magnetic particle, to greatly improve washing
Effect guarantees testing result precision.
The lower section that pedestal 720 is located at substrate 710 is mixed as shown in the figure, and (simple hereinafter along the setting of the length direction of substrate 710
The length direction of substrate 710 be referred to as Y-direction, width direction be X to, thickness direction be Z-direction, such as coordinate instruction reference in Fig. 7), base
The corresponding position for mixing 720 both ends of pedestal in 710 bottom of plate, which is equipped with, mixes pedestal sliding rail 711, mixes pedestal sliding rail 711 along X to setting
Set, mixing has the mixing pedestal sliding block 712 that is slidably matched with it on pedestal sliding rail 711, mix the both ends of pedestal 720 then with it is right
The mixing pedestal sliding block 712 answered is fixedly connected, and mixing pedestal 720 can slide along pedestal sliding rail 711 is mixed, dress mentioned herein
It is upward that fetch bit sets, substrate filling position and washing location are then in X, and driving motor A 71a is equipped with below substrate 710, passes through drive
The automation sliding for mixing pedestal 720 can be realized in dynamic motor A 71a.
Corresponding substrate 710 is equipped with installing port 713, and 713 size of installing port is mutually fitted with washing 730 bottom size of cup holder
It answers, washing cup holder 730 is fixed on the mixing pedestal 720 of support and lower section by installing port 713, and washs the one of cup holder 730
End has outwardly extending isolation A732, sets on substrate 710 in corresponding washing location and dress fetch bit, is respectively equipped with and passes in place
Sensor A714 and reseting sensor B715, isolation A732 are slided with washing cup holder 730, when triggering sensors in place A714,
Mixing pedestal 720 being fed back to backstage by sensors in place A714 and being now in washing location, expression can be washed
Operation, with should isolation A732 triggering reseting sensor B715 when, then to backstage feed back mix pedestal 720 be in dress fetch bit
It sets, expression can carry out mixing operation, or be packed into reaction cup or take out reaction cup operation.
Mixing component 740 in the present embodiment mainly includes being fixedly arranged on the eccentric shaft 741, second mixed on pedestal 720 to mix
Even motor 742 and guiding mechanism, mixing component 740 can follow mixing pedestal 720 to slide together, to reach for different operating conditions
Mixing.
As shown in Fig. 7, Figure 11 and Figure 12, eccentric shaft 741 by bearing in a rotatable manner vertical supporting in mix pedestal
On 720, and close to the one end for mixing pedestal 720, eccentric shaft 741 has two sections of bias up and down, and the second mixing motor 742 is located at
The other end of pedestal 720 is mixed, it is same vertically arranged, and it is located at the lower section for mixing pedestal 720, the second mixing motor 742 passes through
Belt gear is connected with 741 lower end of eccentric shaft, and eccentric shaft 741 can be driven to do rotary motion, and the upper end of eccentric shaft 741
It is fixedly connected with one end of washing cup holder 730.
Guiding mechanism in the present embodiment mainly includes mixed to the X being arranged with Y-direction to mixing sliding rail 743 and Y-direction along X respectively
Even sliding rail 744 is embedded with X to sliding block 745 by groove on pedestal 720 as shown, mixing, and X is to sliding block 745 and mixes pedestal
720 are fixedly connected, and X is slidably matched to mixing sliding rail 743 and X to mixing sliding rail 743, and X is in moving type to sliding rail 743 is mixed
State, Y-direction mix sliding rail 744 and are located at X to mixing above sliding rail 743, and the two is fixedly connected by screw, and Y-direction mixes on sliding rail 744
Sliding block 746 is mixed with the Y-direction being slidably matched with it, and the top that Y-direction mixes sliding block 746 is fixedly connected in washing cup holder 730,
In this way when second mixes motor 742, and eccentric shaft 741 is driven to rotate, it can make to wash cup holder 730 along X to mixing sliding rail 743 and Y
It is slided to the track that sliding rail 744 is constituted is mixed, because eccentric shaft 741 does rotary motion, Gu cup holder is washed in blending process
730 are done the circumference closing motion of horizontal direction accordingly, are conducive to improve mixed effect, and prevent the solution in reaction cup from splashing
It shoots out.
With reference to Fig. 1, Figure 10 and Figure 13, the washing head 750 in the application mainly includes disposed in parallel with washing cup holder 730
Washing head mounting plate 753, as shown, one end of washing head mounting plate 753 is detachably connected with connector 759, connector
759 constitute L-shaped structure with washing head mounting plate 753, and first 759 end position is correspondingly connected on substrate 710 equipped with Z-direction and washs sliding rail
716, Z-direction washing sliding rail 716 is vertically arranged, and there is the Z-direction being slidably matched with Z-direction washing sliding rail 716 to wash on connector 759
Sliding block 754, at the same time, substrate 710 are equipped with for driving washing head mounting plate 753 to wash 716 lifting carriage of sliding rail along Z-direction
Driving motor B 71b equally wash sliding rail in washing head mounting plate 753 and Z-direction and in order to ensure its lifting position is suitable
716 are equipped with mutually matched isolation and sensors in place.
Under normal conditions, when washing needle group 751 or substrate filling needle 752 decline with washing head mounting plate 753, if touching
To lower section reaction cup when, existing driving motor B 71b can drive always washing head 750 continue to decline or mechanical repetition
Lifting action easily causes washing needle group 751 or substrate filling needle 752 to damage in this way, influences detection efficiency, therefore in the present embodiment
Anti-tie cup mechanism is additionally provided on washing head 750, for monitoring washing needle group 751 or bottom during washing head 750 declines
Whether object filling needle 752 collides with reaction cup.
With reference to Figure 15 and Figure 16, it mainly includes nut that the anti-tie cup mechanism in the present embodiment, which is set on connector 759,
Seat 7590, anti-tie isolation 7591 and anti-tie sensor 7592, it is in T-shaped ladder column that wherein nut seat 7590, which is vertical section,
Shape structure, as shown, connector 759 is in hollow structure, it is interior that there is installation cavity 7593 similar with nut seat 7590, the peace
Behave affectedly 7593 upper and lower ends it is open, nut seat 7590 is embedded in installation cavity 7593, and the activity with short transverse is empty
Between, driving motor B 71b is lead screw motor, and Z-direction screw rod 71b0 is arranged downwards, and protrude into installation cavity 7593 with nut
Seat 7590 is threadedly engaged, and 759 upper end end of connector is equipped with pressing plate 7594, and nut seat 7590 is closed in installation cavity by pressing plate 7594
In 7593, prevent it from deviating from from installation cavity 7593.
The elasticity under the double action of gravity and spring 7595 of connector 759 is hung on nut seat 7590, connector 759
Side offers the window 7596 being connected to installation cavity 7593, and window 7596 has certain altitude, anti-tie isolation 7591 and spiral shell
Base 7590 is fixedly connected, and is stretched out from window 7596, and anti-tie sensor 7592 is located on connector 759, and in anti-tie
The underface of isolation 7591.
Under normal conditions, nut seat 7590 is under the support of spring 7595, and in a high position, anti-tie isolation 7591 is also located at this time
In a high position, nut seat 7590 is abutted with pressing plate 7594, it is whole under driving motor B 71b driving can normal lifting carriage, lifting
Nut seat 7590 and 7593 relative position of installation cavity are constant in the process, and when washing needle group 751 or substrate filling needle 752 are touched
When touching, Z-direction washing sliding block 754 is stopped, and cannot continue to glide, while 759 position of connector is motionless, but driving motor B
71b is still in working condition, then Z-direction screw rod 71b0 drives the slide downward in installation cavity 7593 of nut seat 7590, spring 7595
In compressive state, while nut seat 7590 drives anti-tie isolation 7591 also towards lower slider, to trigger anti-tie sensor
7592, anti-tie sensor 7592 passes signal back backstage again, staff or primary control program can be made to quickly understand situation, and do
The case where respective reaction out avoids driving motor B 71b repetitive operation from leading to parts damages, or long-time cannot find the problem hair
It is raw.
On washing head 750 washing needle group 751 along washing head mounting plate 753 length direction be distributed, layout pitch with
Washing hole 731 is adapted, while also being had on washing head mounting plate 753 and being filled sliding rail 755, Y-direction filling along the Y-direction that Y-direction is arranged
There is the Y-direction being slidably matched with it to fill sliding block 756 on sliding rail 755, be installed with substrate needle stand 757 on Y-direction filling sliding block 756,
Substrate filling needle 752 is then fixedly arranged on substrate needle stand 757, and the substrate filling needle 752 in the present embodiment has two, in case filling is not
Two kinds of same substrates need.
Washing head mounting plate 753 is installed with driving motor C 758 close to one end of Z-direction washing sliding rail 716, and setting in this way exists
In the whole steadily of centre of gravity of holding washing head 750, because washing head mounting plate 753 is supported by Z-direction washing sliding block 754 substantially
In on Z-direction washing sliding rail 716, driving motor C 758 is such as set to the other end, then will lead to the increase of other end weight, washing
Head mounting plate 753 is easy to happen deflection, and driving motor C 758 is mainly used for that substrate needle stand 757 is driven to fill sliding rail 755 along Y-direction
Sliding, so that substrate be added into different reaction cups.
In addition, in the application improve washing quality, reduce magnetic particle Loss Rate in terms of also make significant improvement, as Fig. 7,
Shown in Figure 11 and Figure 12, wash similar " 7 " font of vertical section of cup holder 730,731 lower end edge X of washing hole to two sides it is open, base
The corresponding washing location for mixing pedestal 720 is equipped with adsorption plate 760, and the shape of adsorption plate 760 and washing cup holder 730 on plate 710
Rear side shape constitutes complementary structure, and the position of each 731 lower part of the washing hole opening of face is equipped with magnet on adsorption plate 760
761, when mixing when being located at washing location of pedestal 720, adsorption plate 760 is located just at the dead astern of washing cup holder 730, and adsorbs
Plate 760 is close to washing 730 lower part of cup holder, so that the magnetic particle in reaction cup is adsorbed onto rear side by magnet 761, raising is washed
Effect is washed, and can effectively prevent magnetic particle loss.
Herein on basis, to expand its effect, pre- adsorption site 770, pre-suction in the present embodiment are additionally provided on substrate 710
The corresponding dress fetch bit for mixing pedestal 720 of attached seat 770 is set, i.e., when mixing pedestal 720, which is in dress fetch bit, to be set, pre- adsorption site 770 is just
Good to flush with washing cup holder 730, pre- adsorption site 770 is equipped with pre- sucker 771, and opening on rear side of the lower end of pre- sucker 771 is pre- to adsorb
The open position that each pre- sucker 771 is corresponded on seat 770 is installed with pre-suction magnet 772, can be pre- to being put by pre-suction magnet 772
Reaction cup in sucker 771 carries out adsorption treatment, so that the magnetic particle in reaction cup gathers side, simultaneously as the pre-suction time
It is relatively long, it even up to arrives to the further magnetized purpose of magnetic particle, in this way when reaction cup enters washing hole from pre- sucker 771
In 731, when reaching washing location with mixing pedestal 720, the adsorption capacity generated with magnet 761 is stronger, can quickly be adsorbed
To the side wall of reaction cup, and its magnetic force is stronger, in contrast, less easy to be lost, so that magnetic particle Loss Rate is further decreased,
Improve testing result precision.
With reference to Fig. 8, it is contemplated that reduce influence of the temperature to washing or detection, be equipped with and add on substrate 710 in the present embodiment
Thermal 780 can heat the cleaning solution of injection and the substrate of filling, to simplify structure, be easily installed implementation, the application
In driving motor A71a and driving motor C758 be lead screw motor, as shown, driving motor A71a screw rod along mix
Pedestal sliding rail 711 is arranged in parallel, and connect with the threaded one end for mixing pedestal 720, and the screw rod and Y-direction of driving motor C758 fills
Sliding rail 755 is arranged in parallel, and screw rod is threadedly coupled with substrate needle stand 757, in this way when the rotation of the screw rod of respective motor, then can lead to
Crossing screw rod drives the component being correspondingly connected with to slide along corresponding sliding rail.
There are three pre- suckers 771 in the present embodiment, and there are six washing holes 731, and the course of work of the utility model is as follows,
Reaction cup is put into pre- sucker 771 by handgrip first, pedestal 720 is mixed and is set in dress fetch bit as shown in fig. 13 that, passed through
The pre- suction-operated of relatively long time and then the reaction cup that will gradually pass through pre-suction effect be grabbed as in washing hole 731, that is, worked as
After being put into a reaction cup on towards washing cup holder 730, mixes after pedestal 720 is and slide into washing location, pass through washing head 750
Lifting carries out the once washing of the reaction cup, while handgrip supplements reaction cup into pre- sucker 771, when on washing cup holder 730
After first reaction cup completes once washing, mixes pedestal 720 and the dress fetch bit for sliding to front end is set, at this time by pre- adsorption site
Second reaction cup crawl is put into washing hole 731 on 770, is mixed pedestal 720 and is returned to washing location, washs cup holder at this time
First reaction cup carries out second of washing on 730, and first cup carries out first time washing, is successively repeatedly washed by cup
It washs.
In washing process, when washing cup holder 730 far from adsorption plate 760, then it can be mixed by mixing component 740
It is even, so that mixed effect is improved, and after first reaction cup completes certain washing, it mixes pedestal 720 and then slides into bottom
Object fills position, while driving substrate needle stand 757 to slide by driving motor C57, and substrate filling needle 752 is made to be located at the first reaction
The surface of cup is protruded into wherein, and substrate is added into the reaction cup, and is mixed herein by mixing component 740 to it, finally
Mix pedestal 720 slide to dress fetch bit set, first reaction cup is caught away by handgrip, into detection program, and mix pedestal 720 after
The washing of next reaction cup is completed in continuous sliding.It is greatly improved by multiple cleaning function, the pre- suction-operated of cooperation and suction-operated
Washing effect, while reducing magnetic particle Loss Rate, significantly improves testing result precision, while will mix and be combined with washing,
Be conducive to improve washing effect, guarantee testing result reliability.
In addition, being additionally provided with mixing mechanism for the first time between reaction cup storehouse system 400 and incubation system 600 on upper mounting plate 110
150, mixing mechanism 150 is similar to the mixing modular construction in washing system 700 for the first time, is mainly used for solution in reaction cup
For the first time mix, and washing system 700 between detection system 800 be equipped with third mixing mechanism 160, structure with mix for the first time
Even mechanism 150 is similar, and the reaction cup for being mainly used for washing completion and having filled substrate mixes.
With reference to Figure 17 to Figure 19, detection system 800 mainly includes camera bellows cabinet 810, reaction cup holder 820 and inspection in the application
Mechanism 840 is surveyed, camera bellows cabinet 810 is substantially in rectangular parallelepiped structure, is equipped with darkroom 811 in hollow structure, camera bellows inside one end
The position that 810 end of cabinet corresponds to darkroom 811 offers the inlet and outlet 812 communicated therewith, as shown, the court of inlet and outlet 812
To, reaction cup holder 820 face inlet and outlet 812 setting parallel with the length direction of camera bellows cabinet 810, and slided with camera bellows cabinet 810
Dynamic cooperation reacts cup holder as shown, being installed with camera bellows sliding rail 814 on the two sides side wall of camera bellows cabinet 810 along its length
820 left and right ends have the detection sliding block 824 being slidably matched with camera bellows sliding rail 814, and reaction cup holder 820 passes through detection sliding block
824 are slidably matched with camera bellows sliding rail 814, can be close to or far from darkroom 811, while to mention when it is slided along camera bellows sliding rail 814
High overall compactness, the position that camera bellows sliding rail 814 is corresponded on camera bellows cabinet 810 are equipped with the deep gouge of end opening, camera bellows sliding rail 814
In deep gouge, the projecting height on relatively dark 810 surface of box body of camera bellows sliding rail 814 can be reduced in this way.
Reacting cup holder 820 has boss 822 close to the side of inlet and outlet 812, and 822 width of boss and 812 phases of inlet and outlet are suitable
It answers, short transverse is in dual stage scalariform, has top bar and two steps of getting out of a predicament or an embarrassing situation, the two is appeared on the stage in ladder configuration is inverted
Rank ratio, which is got out of a predicament or an embarrassing situation, to be protruded longer, and boss 822 is equipped with and sets glass slot 821, and it is vertically arranged to set glass slot 821, upper and lower open at both ends, instead
Answer cup that can be put into wherein from the top for setting glass slot 821, and the lower end of reaction cup from set show in glass slot 821 come, react cup holder
820 have at least detection position on its sliding stroke and put glass position position Liang Ge, when reaction cup holder 820 is in detection position
When, in 822 position darkroom 811 of boss, inlet and outlet 812 are in closed state, and when react cup holder 820 be in put glass position when,
Boss 822 is in outside darkroom 811, and inlet and outlet 812 are in the open state.
It is to realize when detect position, the adequate closure shading to importing and exporting 812,810 end of camera bellows cabinet in the present embodiment
Portion is equipped with sealed groove 813, as shown, the perpendicularly inward recess of the end wall of sealed groove 813 from camera bellows cabinet 810, and be in
Inlet and outlet 812 outer circumferential, react cup holder 820 on then be equipped with the mutually matched collar flange 823 of sealed groove 813, together
Sample, collar flange 823 is in the outer circumferential of boss 822, and when boss 822 is located in darkroom 811, collar flange 823 is then
In embedding sealing groove 813, play the role of sufficiently being protected from light.
In view of the automation development of instrument, automation degree of equipment is improved, the mobile use of cup holder 820 is reacted in the application
Electric-controlled type driving structure, as shown, being installed with lead screw motor 830 in the side of camera bellows cabinet 810, lead screw motor 830 is along dark
The length direction of box body 810 is arranged, and its screw rod towards and the directions of inlet and outlet 812 be consistent, and with react cup holder 820
It is threadedly engaged, when lead screw motor 830 works, reaction cup holder 820 can be driven to slide along camera bellows sliding rail 814 by screw rod.
It is worth noting that, when react cup holder 820 be in put glass position when, set glass slot 821 and need to expose completely, and
Detection sliding block 824 and camera bellows sliding rail 814 still need to keep mated condition at this time, are in this way to require camera bellows sliding rail 814 to have longer to have
Imitate stroke, then when camera bellows sliding rail 814 is too long, when react cup holder 820 from put glass position towards detection position slide when, and be easy
It interferes therewith, therefore directly the position of face camera bellows sliding rail 814 offers through-hole knot on reaction cup holder 820 in the present embodiment
The via hole 825 of structure, via hole 825 is through the two sides of reaction 820 thickness direction of cup holder, in this way when reaction cup holder 820 is from putting a glass position
When sliding towards detection position, the end of camera bellows sliding rail 814 can be directly protruding into via hole 825, be mutually independent of each other, and that improves structure can
By property.
Optical assembly 843 mainly including lamp guide 841, photoelectric tube 842 and is controlled in testing agency 840 in the present embodiment,
Middle lamp guide 841 is located in camera bellows cabinet 810, and one end is connected to darkroom 811, and when reaction cup holder 820 is in detection position
When, which is located just at the lower section got out of a predicament or an embarrassing situation, the photosensitive end of other end face photoelectric tube 842, and lamp guide 841 can will be in and set cup
The light of liquid exports and passes to photoelectric tube 842 in reaction cup in slot 821, and control optical assembly 843 mainly includes that setting is including
Control tabula rasa 844 between lamp guide 841 and photoelectric tube 842, and the control optical drive motor that driving control tabula rasa 844 rotates horizontally
845, the control driving control tabula rasa 844 of optical drive motor 845, which rotates, can be achieved the logical of the optical path between lamp guide 841 and photoelectric tube 842
It is disconnected, reach preferably control light effect, avoids damaging photoelectric tube 842, prolong its service life.
As shown, the control handstand of optical drive motor 845 is set on camera bellows cabinet 810, motor shaft and control tabula rasa 844 are solid
Fixed connection, and control 845 tail end of optical drive motor and be additionally provided with sensor for detecting its motor shaft rotational angle, to reach accurate
The purpose of control control 844 turned position of tabula rasa, and height space is made full use of, be conducive to improve overall compactness.
In the present embodiment, for the accuracy for improving Photoelectric Detection, the height and position that top bar correspond in darkroom 811, which is equipped with, to be propped up
Boss 816 is supportted, when reaction cup holder 820 is in detection position, boss 822 is located in darkroom 811, while the step of top bar 210
Face is just abutted with the surface of support rim 816, on the one hand plays certain support effect to reaction cup holder 820, on the other hand,
Light-shielding structure as formation labyrinth prevents top from having light intrusion to lamp guide 841, prevents from dripping the influence shone after hanging liquid.
Similarly, it is removably equipped with anti-tampering magnet 850 in the lower end of boss 822, anti-tampering magnet 850 can pass through insertion
Mode install, i.e., setting prepackage hole, anti-tampering magnet 850 is inserted when needed, the side of bonding can also be used
Formula is installed, when specific height and position can refer to reaction cup holder 820 in detection position, anti-tampering magnet 850 just position
In side of the reaction cup far from lamp guide 841, i.e., anti-tampering magnet 850 and lamp guide 841 are located just at reaction cup lower end face
Two sides, anti-tampering magnet 850 only installs and uses when being directed to certain special reagents, will reaction by anti-tampering magnet 850
Magnetic particle in cup in solution is adsorbed to the side far from lamp guide 841, so that weakening magnetic particle suspension blocks influence, further
Improve testing result precision.In addition, the top of camera bellows cabinet 810 be equipped with substrate fill adapter 817, substrate fill adapter 817 with
Darkroom 811 is connected to, and the filling of substrate solution can also be carried out by substrate fill adapter 817, is installed, is convenient in a manner of connector
Later period cleaning or replacement, while the airtightness in darkroom 811 can be effectively ensured.
Referring to figures 20 through Figure 22, the handgrip system 900 of the application mainly includes guide rail bracket 920 and two handgrip mechanisms 910,
Wherein guide rail bracket 920 includes X direction guiding rail 922, Y-direction guide rail 921 and Z-direction guide rail 923, and two handgrip mechanisms 910 share a Y-direction
Guide rail 921, Y-direction guide rail 921 is set to the top of upper mounting plate 110, and is arranged along its Y-direction, and both ends are fixed in rack 100,
Each handgrip mechanism 910 has the X direction guiding rail 922 and Z-direction guide rail 923 being separately provided, and 923 upper end of Z-direction guide rail passes through sliding block and Y
Direction guiding rail 921 is slidably matched, i.e., Z-direction guide rail 923 is whole to slide along Y-direction guide rail 921, and X direction guiding rail 922 passes through sliding block and Z-direction
Guide rail 923 is slidably matched, and such X direction guiding rail 922 is whole to be moved up and down along Z-direction guide rail 923, and can follow Z-direction guide rail 923
It is slided along Y-direction guide rail 921.
Handgrip mechanism 910 includes handgrip seat 911, and handgrip seat 911 can be along X direction guiding rail 922, Y under the driving of driving mechanism
Direction guiding rail 921 and Z-direction guide rail 923 carry out three-dimensional sliding, and 911 bottom of handgrip seat is equipped with suction nozzle 912, and suction nozzle 912 is connected by pipeline
It is connected to positive pressure source and negative pressure source, and is controlled respectively by positive valve 962 and negative pressure valve 961, and be correspondingly arranged on air
Pressure sensor 963, and air pump 960 is used to provide the structure of positive pressure and negative pressure for two suction nozzles 912 in the present embodiment, air pump
960 be vacuum pump, can follow directly after corresponding handgrip movement, reduce length of pipe, it is ensured that the accuracy of positive/negative-pressure value.
Referring to figs. 1 to Figure 22, the course of work of the utility model is as follows: the cup holder 420 for filling reaction cup is passed through cup holder
It is put into mouth 131 to be put into glass orlop seat 410, sample tube is located in sample-feed system 200, in agent bin storage system 300
Equipped with required reagent, it is in armed state, transshipment acitivity 140 is then put by handgrip mechanism 910, and utilize loading system
500 carry out the filling of sample, reagent and magnetic particle, and are diluted operation as needed, are then mixed for the first time by handgrip feeding
Even mechanism 150, is mixed for the first time, is mixed after completing for the first time, is sent into incubation system 600 and is incubated for, is incubated for after completing
It is then sent into washing system 700, carries out repeatedly mixing washing according to washing methods above-mentioned, enters third mixing machine after the completion of washing
Structure 160, carries out substrate mixing, this time mixes and is sent into station to be detected after completing and (station to be detected and is incubated in the present embodiment
System 600 shares, and makes full use of 600 space of incubation system to complete detection and waits), it waits after a certain period of time, finally by handgrip
It will be fed into detection system 800, carry out the luminous detection of camera bellows, after detection is completed, reaction cup holder 820 is in outside darkroom 811,
Reaction cup is grabbed by handgrip, and passes through waste port 112 and throws into the waste bin 121 of lower section.
To fully ensure that the cleanliness for detecting environment, therefore the appearance of instrument is coated with heat-insulated shell 130, at the same time,
The top of rack 100 is equipped with temperature adjusting mechanism 170, and temperature adjusting mechanism 170 can be blown according to the temperature inside shell 130
Hot wind out reduces influence of the temperature to testing result, is correspondingly provided with radiation air on shell 130 so as to adjust internal bulk temperature
Fan, when internal temperature is excessively high, then can be cooled down by air discharging and radiating mode, reaction cup storehouse system 400 is corresponded on shell 130
Position offer cup holder and be put into mouth 131, in this way can be convenient for manually filling into the cup holder 420 for being loaded with reaction cup, shell from there
The position that sample-feed system 200 is corresponded on 130 offers sample and is put into mouth 132, it is replenished in time conveniently and is loaded with sample examination
The rack for test tube of pipe is equipped with reagent in the position of corresponding reagent storage system 300 and is put into mouth 134, similarly, in corresponding waste bin 121
Position be equipped with waste material outlet 133, in this way can more easily will equipped with waste material (referring to used reaction cup) box take out
It is replaced.
Finally, it should be noted that foregoing description is only the preferred embodiment of the utility model, the common skill of this field
Art personnel are under the enlightenment of the utility model, under the premise of without prejudice to the utility model aims and claim, can make
Multiple similar expressions, such transformation are each fallen within the protection scope of the utility model.
Claims (10)
1. a kind of efficient chemical luminescence immunoassay instrument, it is characterised in that: the rack (100) including being in frame structure, the rack
(100) there is upper mounting plate (110) and lower platform (120), be successively arranged reaction cup along its length on the upper mounting plate (110)
Storehouse system (400) and incubation system (600), and one jiao of reaction cup storehouse system (400) close upper mounting plate (110), the reaction
The side of cup storehouse system (400) is equipped with loading system (500), and the side of incubation system (600) is equipped with washing system (700), on
One end on platform (110) far from reaction cup storehouse system (400) is equipped with detection system (800), and the rack (100) is in upper mounting plate
(110) handgrip system (900) are provided with above；
It is equipped with sample-feed system (200) and reagent storage system (300) by the position of close end on the lower platform (120),
And the reagent storage system (300) is located at immediately below loading system (500), wherein reaction cup storehouse system (400) is for storing
Supply response cup, loading system (500) are used to that sample, reagent and magnetic particle liquid to be added into reaction cup molten to form mixing
Liquid, handgrip system (900) are used for movement of the reaction cup between each system, and washing system (700) is used for solution in reaction cup
It carries out the filling of washing substrate and mixes operation.
2. efficient chemical luminescence immunoassay instrument according to claim 1, it is characterised in that: wrapped on the rack (100)
It is covered with shell (130), the position that reaction cup storehouse system (400) is corresponded on the shell (130) offers cup holder and is put into mouth
(131), the position of corresponding sample-feed system (200) offers sample and is put into mouth (132), corresponding reagent storage system (300)
It is provided with reagent to be put into mouth (134), is provided with surge flask storehouse (180) at the top of rack (100)；
It is additionally provided with waste port (112) on the upper mounting plate (110), the position of face waste port (112) is equipped on lower platform (120)
Waste bin (121), the position that waste bin (121) is corresponded on the shell (130) are equipped with waste material outlet (133), the rack
(100) temperature adjusting mechanism (170) are equipped with.
3. efficient chemical luminescence immunoassay instrument according to claim 1, it is characterised in that: the washing system (700)
Including substrate (710), pedestal (720), washing cup holder (730), mixing component (740) and washing head (750) are mixed, wherein substrate
(710) it is fixedly arranged on upper mounting plate (110), mixes pedestal (720) and be movably set on substrate (710), and can opposing substrate (710)
Sliding on sliding stroke there is dress to take, three positions of substrate filling and washing；
It wherein washs cup holder (730) and mixes component (740) and be all set in mixing pedestal (720), washing cup holder (730) has
Washing hole (731) distributed along its length mixes component (740) for keeping washing cup holder (730) past in horizontal plane
Physical pendulum is dynamic, will be movably set in substrate (710) in the liquid blending in reaction cup in washing hole (731), washing head (750)
On, and can be moved up and down with respect to upper mounting plate (110), washing head (750) has washs needle with washing hole (731) correspondingly
Group (751) and at least one substrate filling needle (752) wash needle group when mixing pedestal (720) is in washing location
(751) it is located at right above washing hole (731), when in substrate filling position, substrate filling needle (752) is located at washing hole
(731) surface.
4. efficient chemical luminescence immunoassay instrument according to claim 3, it is characterised in that: the mixing pedestal (720)
Positioned at the lower section of substrate (710), the corresponding position for mixing pedestal (720) both ends in substrate (710) bottom, which is equipped with, mixes pedestal sliding rail
(711), described mix has the mixing pedestal sliding block (712) cooperated with its sliding rail, the mixing pedestal on pedestal sliding rail (711)
(720) both ends are fixedly connected with corresponding mixing pedestal sliding block (712) respectively；
The substrate, which is equipped with, mixes pedestal (720) along the driving motor A for mixing pedestal sliding rail (711) sliding for driving
(710a), the corresponding sliding stroke for mixing pedestal (720) is equipped with installing port (713) on substrate (710), and upper mounting plate (110) is corresponding
The position of installing port (713) has through-hole.
5. efficient chemical luminescence immunoassay instrument according to claim 3, it is characterised in that: on the washing head (750)
Equipped with anti-tie cup mechanism, the anti-tie cup mechanism is used for monitoring washing needle group (751) and bottom during washing head (750) decline
Whether object filling needle (752) is touched with reaction cup.
6. efficient chemical luminescence immunoassay instrument according to claim 1, it is characterised in that: the detection system (800)
Including camera bellows cabinet (810) and testing agency (840), darkroom (811) are equipped in camera bellows cabinet (810), testing agency (840) is solid
On camera bellows cabinet (810), the inlet and outlet (812) being connected to darkroom (811) are offered on the side wall of camera bellows cabinet (810),
Testing agency (840) is used to detect the luminous quantity of liquid in reaction cup in darkroom (811)；
The camera bellows cabinet (810), which is equipped with, reacts cup holder (820) with what it was slidably matched, which is equipped with
Upper lower open mouth is set a glass slot (821), and react cup holder (820) can the sliding of relatively dark box body (810) to open or close disengaging
Mouth (812) sets a glass slot (821) and is exposed to darkroom (811) outside when inlet and outlet (812) are opened, when inlet and outlet (812) are closed
When, it sets a glass slot (821) and is in darkroom (811).
7. efficient chemical luminescence immunoassay instrument according to claim 6, it is characterised in that: the reaction cup holder (820)
The position that upper correspondence sets a glass slot (821) has in step-like detection boss (822), and the lower end of the detection boss (822) has
Along the anti-tampering magnet (850) of reaction cup holder (820) thickness direction setting, the anti-tampering magnet (850) is located remotely from detection
The side of mechanism (840).
8. efficient chemical luminescence immunoassay instrument according to claim 1 or 2, it is characterised in that: the reaction cup storehouse system
System (400) includes cup orlop seat (410) and cup holder (420), and the cup orlop seat (410) is equipped at least one and is used for cup placement
The accommodation groove of frame (420), the accommodation groove open topped are distributed with for upright placing response cup on the cup holder (420)
Accommodating hole, the accommodating hole is vertically arranged, and the bottom of the cup orlop seat (410) is equipped with heating device A, cup orlop seat (410)
It is equipped with temperature sensor A.
9. efficient chemical luminescence immunoassay instrument according to claim 1 or 2, it is characterised in that: the handgrip system
It (900) include guide rail bracket (920) and two handgrip mechanisms (910), wherein guide rail bracket (920) includes that X direction guiding rail (922), Y-direction are led
Rail (921) and Z-direction guide rail (923), the handgrip mechanism (910) include handgrip seat (911), and the handgrip seat (911) is driving
Three-dimensional sliding, the handgrip can be carried out along X direction guiding rail (922), Y-direction guide rail (921) and Z-direction guide rail (923) under the driving of mechanism
Seat (911) bottom is equipped with suction nozzle (912), and the lower end of the suction nozzle (912) is bonded with rubber, and the suction nozzle (912) passes through
Pipeline is connected with positive pressure source and negative pressure source, or is connected to air pump (960) by pipeline.
10. efficient chemical luminescence immunoassay instrument as claimed in any of claims 1 to 7, it is characterised in that: described
Reagent storage system (300) includes agent bin (310), and at least two are equipped at the top of the agent bin (310) and is connected to its inside
Lower pinhole (311), be equipped at the top of the agent bin (310) and agent bin (310) inside the dilution bottle fixing seat that is connected to
(320), the dilution bottle fixing seat (320) is for placing dilution bottle.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201920231908.1U CN209590044U (en) | 2019-02-20 | 2019-02-20 | High-efficiency chemiluminescence immunoassay analyzer |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201920231908.1U CN209590044U (en) | 2019-02-20 | 2019-02-20 | High-efficiency chemiluminescence immunoassay analyzer |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109856390A (en) * | 2019-02-20 | 2019-06-07 | 重庆科斯迈生物科技有限公司 | Miniature high-efficiency chemiluminescence immunoassay analyzer |
| CN112881719A (en) * | 2019-11-30 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Blood analyzer and detection device |
| CN114152496A (en) * | 2021-12-31 | 2022-03-08 | 河南赛诺特生物技术有限公司 | Automatic immunohistochemical dyeing machine |
| WO2023160360A1 (en) * | 2022-02-28 | 2023-08-31 | 南京诺尔曼生物技术股份有限公司 | Luminescence detection system and method capable of providing quick results |
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2019
- 2019-02-20 CN CN201920231908.1U patent/CN209590044U/en active Active
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109856390A (en) * | 2019-02-20 | 2019-06-07 | 重庆科斯迈生物科技有限公司 | Miniature high-efficiency chemiluminescence immunoassay analyzer |
| WO2020168871A1 (en) * | 2019-02-20 | 2020-08-27 | 重庆科斯迈生物科技有限公司 | Miniature efficient chemiluminescence immunoassay analyzer |
| CN109856390B (en) * | 2019-02-20 | 2023-06-13 | 重庆科斯迈生物科技有限公司 | Miniature high-efficiency chemiluminescent immunoassay instrument |
| CN112881719A (en) * | 2019-11-30 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Blood analyzer and detection device |
| CN112881719B (en) * | 2019-11-30 | 2024-01-16 | 深圳市帝迈生物技术有限公司 | Blood analyzer and detecting device |
| CN114152496A (en) * | 2021-12-31 | 2022-03-08 | 河南赛诺特生物技术有限公司 | Automatic immunohistochemical dyeing machine |
| WO2023160360A1 (en) * | 2022-02-28 | 2023-08-31 | 南京诺尔曼生物技术股份有限公司 | Luminescence detection system and method capable of providing quick results |
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