CN203908840U - Microcomputer-controlled liquid-based cell sheet preparation dyeing system - Google Patents
Microcomputer-controlled liquid-based cell sheet preparation dyeing system Download PDFInfo
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- CN203908840U CN203908840U CN201420303599.1U CN201420303599U CN203908840U CN 203908840 U CN203908840 U CN 203908840U CN 201420303599 U CN201420303599 U CN 201420303599U CN 203908840 U CN203908840 U CN 203908840U
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Abstract
The utility model discloses a microcomputer-controlled liquid-based cell sheet preparation dyeing system which comprises a shell as well as a dyeing device, a mechanical rotating arm device, a precise quantitative liquid adding device and an electronic control type auxiliary device which are arranged in the shell, wherein the shell comprises a main body, a rear sealing plate arranged in back of the main body, and a dyeing pot cover positioned on the top of the main body; a display operation screen is arranged above the front surface of the main body; the interior of the shell is divided into an upper cavity and a lower cavity by a fiducial bottom plate; the upper cavity is divided into a left part and a right part; the left part is used as a specimen placing bin; the right part is used as a containing and dyeing device. By using the microcomputer-controlled liquid-based cell sheet preparation dyeing system, the operations of automatic specimen feeding, specimen centrifuging, cell sheet preparation and cell dyeing can be completed on one instrument, and no operator is required during the operations; a prepared liquid-based cell sheet is stable in quality, integrate in cell structure, and uniform in distribution; the microcomputer-controlled liquid-based cell sheet preparation dyeing system is suitable for being used in large-scale physical examination, cancer prevention census, and clinical diagnosis and screening in large specialized and comprehensive hospitals.
Description
Technical field
The utility model relates to a kind of microcomputerized control liquid-based cell sample manufacturing coloring system, belongs to medical treatment detection device technical field.
Background technology
Exfoliative cytology is exactly the method for utilizing the normal cast-off cells of tissue to diagnose, liquid based cytology is a part for exfoliative cytology, that the liquid that reluctant exfoliative cytology sample is put into a kind of intermediary is in a traditional way gone, to remove the interference component of the impact diagnosis such as blood, mucus, reach the object that improves diagnosis.The liquid of intermediary is called as cell-preservation liquid, and it has the cellular morphology of maintenance, softening mucus, processes the functions such as red blood cell.
Liquid based cytology inspection is to adopt liquid-based thin-layer cell detection system detect cell and carry out cytological classification diagnosis, it is current more advanced a kind of cytolgical examination technology in the world, compare with traditional Pap smear inspection, obviously improved satisfaction and the abnormal cell recall rate of sample.
Liquid based cytology is mainly used in human body cell sample to carry out the dyeing of cytology coloring agent smear, make standardized cytologic slide, be convenient to diagnosis, meet the requirement of clinical screening and family planning generaI investigation, for medical test and biological study, particularly significant aspect cytology and bacterial micro-organism check (generaI investigation of gynecological tumor generaI investigation, tulase, the inspection of chest ascites cell etc.).But film-making and the artificial application of sample of dyeing, centrifugal, film-making and dyeing course very complicated, waste time and energy, be difficult in enormous quantities, high-level efficiency film-making dyeing.
Summary of the invention
Technical problem to be solved in the utility model is to provide a kind of microcomputerized control liquid-based cell sample manufacturing coloring system that application of sample, film-making and dyeing integration are realized that collects.
The utility model is achieved through the following technical solutions: a kind of microcomputerized control liquid-based cell sample manufacturing coloring system, this film-making coloring system comprises casing and is positioned at the dyeing apparatus of casing inside, machinery full wind-up device, accurate quantitative liquid feeding apparatus and automatically controlled servicing unit, described casing comprises main body, be positioned at the rear shrouding and the dyeing pot cover that is positioned at main body top at main body rear, above main body front, be provided with display operation screen, described casing inside is divided into by a benchmark base plate, lower chambers, described upper chamber is divided into again a left side, right half, left part is divided into sample place position, right part is divided into and holds dyeing apparatus, the accurate liquid volume added control device of chamber housing and the automatically controlled servicing unit that hold dyeing apparatus below, described casing upper right end is provided with application of sample storehouse,
Dyeing apparatus comprises dyeing kettle body, dyeing kettle body upper cap has dyeing kettle body lid, at dyeing pot nside, be provided with dyeing centrifugal pan, dyeing dish below is provided with the dyeing of rotary power main drive gear is provided, above the side of dyeing centrifugal pan, be provided with the dyeing syringe needle for the liquid feeding that dyes, this dyeing syringe needle one side is provided with a rinse bath, and a preparation bin is installed in the draw-in groove of described dyeing centrifugal pan;
Precisely quantitative liquid feeding apparatus comprises power control unit and liquid feed device, wherein, power control unit comprises mounting bracket and is positioned at 7 membrane pumps and 1 the three-way solenoid valve formation on mounting bracket, membrane pump output terminal distributes and is connected with the liquid filling syringe needle on mechanical full wind-up device, a side at mounting bracket is provided with the microcomputer circuit controller of controlling accurate quantitative liquid feeding apparatus work, and liquid feed device comprises a plurality of liquid transfer systems that consist of complete machine the external fluid storage tanks of port and waste liquid recycling can;
Automatically controlled servicing unit is for each unit module of complete machine provides the CPU central processing system of accurate instruction, comprises dyeing apparatus, the accurate action command of quantitative liquid feeding apparatus, mechanical full wind-up.
As preferred technical scheme, described main body covers front, the He Liangge side, bottom surface of casing.
As preferred technical scheme, the lower end of described dyeing centrifugal pan is provided with a motor shaft bearing sleeve, the lower end of this motor shaft bearing sleeve connects a shaft coupling, described shaft coupling be motor fixing seat, the lower end of described motor fixing seat is rotary power motor, and described shaft coupling is connected with the rotary power motor of lower end through motor fixing seat.
As preferred technical scheme, described preparation bin comprises a photo making cup, microslide and film-making base.
As preferred technical scheme, described mechanical full wind-up device comprises one first motor, first, second guide shaft, the second motor, synchronizing wheel and central shaft.
The beneficial effects of the utility model are: 1, saved time and manpower, greatly improved film-making dyeing efficiency;
2, microcomputer control criterionization operation, reduces personal error, has improved liquid base film-making dyeing quality, is convenient to mass disposal sample, is especially convenient to clinical diagnosis and the examination of extensive anti-cancer generaI investigation and large-scale training, general hospital;
3, realized the systematicness of application of sample, centrifugal, film-making, dyeing, centre is put and is kept without personnel, made liquid base smear steady quality, eucaryotic cell structure be complete, be evenly distributed, and being especially convenient to clinical diagnosis and the examination of extensive anti-cancer generaI investigation and large-scale training, general hospital.
Accompanying drawing explanation
In order to be illustrated more clearly in the utility model embodiment or technical scheme of the prior art, to the accompanying drawing of required use in embodiment or description of the Prior Art be briefly described below, apparently, accompanying drawing in the following describes is only embodiment more of the present utility model, for those of ordinary skills, do not paying under the prerequisite of creative work, can also obtain according to these accompanying drawings other accompanying drawing.
Fig. 1 is the outside three-dimensional structure diagram of the utility model;
Fig. 2 is front view of the present utility model;
Fig. 3 is A1-A1 cross-sectional view in Fig. 2;
Fig. 4 is A2-A2 cross-sectional view in Fig. 2;
Fig. 5 is B-B cross-sectional view in Fig. 2;
Fig. 6 is the cross-sectional view of T-T in Fig. 2;
Fig. 7 is the structural representation of the utility model dyeing apparatus;
Fig. 8 is the structural representation of the utility model machinery full wind-up device.
Embodiment
Disclosed all features in this instructions, or the step in disclosed all methods or process, except mutually exclusive feature and/or step, all can combine by any way.
Disclosed arbitrary feature in this instructions (comprising any accessory claim, summary and accompanying drawing), unless narration especially all can be replaced by other equivalences or the alternative features with similar object.That is,, unless narration especially, each feature is an example in a series of equivalences or similar characteristics.
As Fig. 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6, shown in Fig. 7 and Fig. 8, a kind of microcomputerized control liquid-based cell sample manufacturing coloring system, this film-making coloring system comprises casing and is positioned at the dyeing apparatus of casing inside, machinery full wind-up device 5, accurate quantitative liquid feeding apparatus and automatically controlled servicing unit, described casing comprises main body 1, be positioned at the rear shrouding 2 and the dyeing pot cover 3 that is positioned at main body top at main body rear, above main body front, be provided with display operation screen 4, described casing inside is divided into by a benchmark base plate 12, lower chambers, described upper chamber is divided into again a left side, right half, left part is divided into sample place position 6, right part is divided into and holds dyeing apparatus, the accurate liquid volume added control device of chamber housing and the automatically controlled servicing unit 15 that hold dyeing apparatus below, described casing upper right end is provided with application of sample storehouse,
Dyeing apparatus comprises dyeing kettle body 8, dyeing kettle body upper cap has dyeing kettle body lid 3, in dyeing kettle body 8 inside, be provided with dyeing centrifugal pan 10, dyeing dish below is provided with the dyeing of rotary power main drive gear 7 is provided, above the side of dyeing centrifugal pan, be provided with the dyeing syringe needle 11 for the liquid feeding that dyes, these dyeing syringe needle 11 1 sides are provided with a rinse bath 19, and a preparation bin 21 is installed in the draw-in groove of described dyeing centrifugal pan 10;
Precisely quantitative liquid feeding apparatus 13 comprises power control unit and liquid feed device, wherein, power control unit comprises mounting bracket 30 and is positioned at 7 membrane pumps and 1 the three-way solenoid valve formation on mounting bracket 30, membrane pump output terminal distributes and is connected with the liquid filling syringe needle on mechanical full wind-up device, a side at mounting bracket is provided with the microcomputer circuit controller of controlling accurate quantitative liquid feeding apparatus work, and liquid feed device comprises a plurality of liquid transfer systems that consist of complete machine the external fluid storage tanks of port and waste liquid recycling can;
Automatically controlled servicing unit is for each unit module of complete machine provides the CPU central processing system of accurate instruction, comprises dyeing apparatus, the accurate action command of quantitative liquid feeding apparatus, mechanical full wind-up.
As preferred technical scheme, described main body covers front, the He Liangge side, bottom surface of casing.
As preferred technical scheme, the lower end of described dyeing centrifugal pan is provided with a motor shaft bearing sleeve 18, the lower end of this motor shaft bearing sleeve 18 connects a shaft coupling 17, described shaft coupling 17 be motor fixing seat 14, the lower end of described motor fixing seat 14 is rotary power motor 16, and described shaft coupling 17 is connected with the rotary power motor 16 of lower end through motor fixing seat 14.
As preferred technical scheme, described preparation bin comprises a photo making cup (not shown), microslide and film-making base.
As preferred technical scheme, described mechanical full wind-up device comprises one first motor 31, first, second guide shaft 32,33, the second motor 34, synchronizing wheel 35 and central shaft 36.
Workflow is as follows: open after instrument power source, system automatically resets.Operating personnel select corresponding mode of operation, and preparation bin is installed is packed in draw-in groove that centrifugal pan is corresponding (as shown in Fig. 7 21), build dyeing pot cover 3, the START button on display operation screen 4, instrument completes smear staining work by following work journey automatically:
The first step: inject cell separation liquid in film-making cabin on the dyeing centrifugal pan 10 that the dyeing main drive gear 7 of the rotary power that the mechanical full wind-up device 5 of dyeing syringe needle 11 dependence is provided with to dyeing kettle body 8 inside is controlled, cell separation liquid forms column liquid level in film-making cabin.
Second step: dyeing syringe needle 11 relies on mechanical full wind-up device 5 to rotate to the position of specimen bottle, slowly be insinuated in sample bottle, the sample that precisely quantitative liquid feeding apparatus 13 startup controls are dyeed in 11 pairs of specimen bottles of syringe needles carries out the suction of 3 times repeatedly and mixes, completing poststaining syringe needle 11 draws sample liquid and gets back to dyeing kettle body 8 inside and be provided with the corresponding filling position, film-making cabin 21 on dyeing centrifugal pan 10, and press specific dosing method and to film-making cabin, inject sample, after note, form sample on upper strata, the special two-layer liquid column of cell separation Ye lower floor.Sampler completes the action of filling, and then, dyeing syringe needle 11 relies on mechanical full wind-up device 5 to rotate in rinse bath 19 and sprays cleaning, has cleaned poststaining syringe needle 11 and has relied on mechanical full wind-up device 5 to rotate to the position of next sample thief bottle.
The 3rd step: repeat second step until all samples are all filled in the corresponding film-making cabin on dyeing centrifugal pan 10.
The 4th step: the time that the dyeing main drive gear 7 of rotary power drives dyeing centrifugal pan 10 to set according to setting speed rotation, cell carries out Selective Separation in cell separation liquid, cell is according to suspending or decline precipitation than close and charge characteristic layering, the final interference component that forms the impact diagnosis such as mucus, red blood cell each layer that suspend, and effective histocyte composition is deposited to film-making cabin bottommost one deck and adheres on the microslide of special processing.
The 5th step: the dyeing main drive gear 7 of rotary power is controlled dyeing centrifugal pan 10 and stopped the position of getting liquid to dyeing syringe needle 11, and dyeing syringe needle 11 drops in film-making cabin draws waste liquid one by one, after absorption completes.Equipment carries out further separated valuable diagnosis cell be deposited to film-making cabin bottommost one deck and adhere on the microslide of special processing of centrifuging next time according to Electronic Control automatically: and then dyeing syringe needle 11 drops to and in film-making cabin, draws one by one waste liquid and after absorption completes, inject a kind of dyeing liquor, after injection completes, according to the time that the current film-making cabin dyeing liquor immersion of timing is set, the syringe needle 11 that simultaneously dyes cleans to rinse bath.
The 6th step: circulation the 5th step is until all complete the action of injecting a certain liquid in all film-making windows.Timing time arrives, and carries out next step.
The 7th step: the position that dyeing centrifugal pan 10 is got liquid to dyeing syringe needle 11 is controlled in dyeing main drive gear 7 rotations of rotary power, dyeing syringe needle 11 drops to draws waste liquid in preparation bin, a kind of dyeing liquor under injecting after absorption completes, after injection completes according to the time that the current film-making cabin dyeing liquor of timing is set soaks, when timing to after absorption waste liquid.Complete and draw the rear another kind of dyeing liquor that injects, after injection completes, according to the time that the current film-making cabin dyeing liquor immersion of timing is set, the syringe needle that simultaneously dyes cleans to rinse bath 19.
The 8th step: circulation the 7th step.Amount to 5-10 circulation
The 9th step: draw waste liquid, dyeing syringe needle cleans to rinse bath 19.
The tenth step: circulation the 9th step is until all waste liquid absorption in film-making cabin is complete, and system automatically resets, waits for next instruction, and full operation flow process finishes.
Principle of work or technology are decomposed as follows: principle of work or technology are decomposed passing through as shown in Figure 3 and Figure 5 of (), patent of the present invention, dyeing apparatus comprises dyeing kettle body 8, dyeing kettle body 8 upper caps have dyeing pot cover 3, in dyeing kettle body 8 inside, be provided with dyeing centrifugal pan 10, dyeing centrifugal pan 10 belows are provided with the dyeing of rotary power main drive gear 7 are provided, this mechanism is that can in conjunction with electronic circuit control, can realize low speed by this physical construction locates, and can realize separated parallel existence of high speed centrifugation.Can implement to support to realize to complete in same equipment: the repeatedly centrifuging under different centrifugal speeds, cell settlement is to adhesion slide glass and the location of the low speed in dyeing course of special processing.The dyeing main drive gear 7 that has solved the common rotary power of common use can only the single speed of single carries out the difficult point of separated various samples.Thereby for realizing application of sample, centrifugal, film-making, dyeing integration, the present invention provides prerequisite guarantee.
Principle of work or technology are decomposed passing through as shown in Figure 3 and Figure 5 of (two) patent of the present invention, dyeing apparatus comprises dyeing kettle body 8, dyeing kettle body 8 upper caps have dyeing pot cover 3, in dyeing kettle body 8 inside, be provided with dyeing centrifugal pan 10, dyeing centrifugal pan 10 belows are provided with the dyeing of rotary power main drive gear 7 are provided, above the side of dyeing centrifugal pan 10, be provided with for the syringe needle 11 that dyes, utilize accurate quantitative liquid feeding apparatus 13, according to the workflow first step: dyeing syringe needle 11 relies on the automatically controlled servicing unit 11 of microcomputer the cell separation liquid in external liquid storage vessel to be provided with to the cell separation liquid that injects formulated on dyeing centrifugal pan 10 in film-making cabin to dyeing kettle body 8 inside, cell separation liquid forms column liquid level in film-making cabin, completing as multi_layer extraction in workflow the 4th step extracts has the crucial prerequisite of the cell of diagnostic value to prepare.The specific (special) requirements of patent of the present invention is the close cell separation liquid of the ladder of formulated, can form electric charge layer distributed, density forms gradient suspension layering, can rely on power control unit transmission uniformly to transport, and be provided with to dyeing kettle body 8 inside the cell separation liquid that injects formulated in the film-making cabin on dyeing centrifugal pan 10.Patent of the present invention adopts chooses the extracting and demixing special polymer substance that combines with density gradient, practice respectively in sample liquid storage and cell separation liquid in shape electric charge two-phase and from degree gradient, guarantee the removing of erythrocytic multi_layer extraction and mucus, guarantee the smooth enforcement of above-mentioned technology.Exempt similar products at home and abroad artificial with mixing traditional gradient density fluid, and use quantitative liquid shifter, quantitatively move liquid bottle or quantitative straw etc. and in centrifuge tube, add traditional gradient density fluid process successively.The standardization that patent of the present invention has been applied machinery and electronics programming Control is accurate, unitarity realizes filling simultaneously, guarantees made liquid base smear steady quality.
Passing through as shown in Figures 4 and 5 of principle of work or technology decomposition (three) patent of the present invention, the dyeing syringe needle 11 of sample place position 6 tops relies on mechanical full wind-up device 5, in conjunction with the light realization of accurate quantitative liquid feeding apparatus 13, sample is carried out to pressure-vaccum and mixes and draw the object that sample turn is annotated according to specific (special) requirements to assigned address.Then the syringe needle 11 that dyes relies on mechanical full wind-up device 5 to rotate to rinse bath 19 and sprays cleaning, implement to shift sample, avoids cross pollution simultaneously.Exempt similar products at home and abroad manually with pipettor or disposable pasteur pipet, change disposable quantitative straw or change quantitative liquid shifter Tip first-class repeatedly inhale blow sample break up mix, the careful numerous labor process of complexity that slowly adds to the transfer application of sample of centrifuge tube.The standardization that patent of the present invention has been applied machinery and electronics programming Control is accurate, stability realizes filling sample simultaneously, guarantees made liquid base smear steady quality.
Principle of work or technology are decomposed passing through as shown in Figure 3 and Figure 5 of (four) patent of the present invention, dyeing apparatus comprises dyeing kettle body 8, dyeing kettle body 8 upper caps have dyeing pot cover 3, in dyeing kettle body 8 inside, be provided with dyeing centrifugal pan 10, dyeing centrifugal pan 10 belows are provided with the dyeing of rotary power main drive gear 7 are provided, this mechanism is can be by realizing high speed centrifugation separation in conjunction with electronic circuit control, afterwards according to workflow the 4th step: the time that the dyeing main drive gear 7 of rotary power drives dyeing centrifugal pan 10 to set according to setting speed rotation, cell carries out Selective Separation in cell separation liquid, cell is according to suspending or decline precipitation than close and charge characteristic layering, the final mucus that forms, the interference component of the impact such as red blood cell diagnosis each layer that suspend, and effectively histocyte composition is deposited to film-making cabin bottommost one deck and adheres on the microslide of special processing.Simultaneously the dyeing main drive gear 7 of rotary power is controlled dyeing centrifugal pans 10 and is stopped the position of getting liquid to dyeing syringe needle, and dyeing syringe needle 11 drops to absorbs waste liquid one by one in film-making cabin.Carry out further separated valuable diagnosis cell be deposited to film-making cabin bottommost one deck and adhere on the microslide of special processing of centrifuging next time: the syringe needle that then dyes drops to again draws waste liquid one by one in film-making cabin, finally make the cell smear of an international standard, and be retained in wait low speed location cleaning and dyeing automatically in film-making cabin.Patent application machine of the present invention and electronics programming Control have ensured centrifuging time and speed, guaranteed that the accurate height face one of absorbing waste liquid fixes on the formation connector loop place that extracts two-phase simultaneously, ensured the purification degrees of cell separation, made liquid base smear steady quality, eucaryotic cell structure be complete, be evenly distributed, and being especially convenient to clinical diagnosis and the examination of extensive anti-cancer generaI investigation and large-scale training, general hospital.
Principle of work or technology are decomposed passing through as shown in Figure 3 and Figure 5 of (five) patent of the present invention, dyeing apparatus comprises dyeing kettle body 8, dyeing kettle body 8 upper caps have dyeing pot cover 3, in dyeing kettle body 8 inside, be provided with dyeing centrifugal pan 10, dyeing centrifugal pan 10 belows are provided with the dyeing of rotary power main drive gear 7 are provided, above the side of dyeing centrifugal pan 10, be provided with for the syringe needle 11 that dyes, utilize accurate quantitative liquid feeding apparatus 13 on mounting bracket 30, according to workflow the 6th, seven, eight, nine, ten steps, automatically complete.Removed staining rack on slide dismounting that workload is large, slide process and time-consuming, pollute dyeing course large, very complicated that staining procedure is various.Greatly liberate technician's labour, can be engaged in the technical work of more high-load.The hydraulic fluid that simultaneously dyes is in the cavity volume of sealing, avoid the factors such as folding lid or open container volatilization, cross-reference, guaranteed the homogeneity of dyeing work, and computer is strictly controlled dyeing time, the extraneous factor of stopping personnel is disturbed and the factors such as time disunity have guaranteed the standardization of dyeing time.In whole process, all in liquid, under hygrometric state, guaranteed that cell is not caused cytomorphosis or local weathering by air-dry or baking simultaneously.
Principle of work or technology are decomposed (seven) patent of the present invention and are decomposed the technology prerequisites such as (), (two) (three), (four), (five), (six) by principle of work or technology, the normally used device in this area can be arranged in a machine, and can combine and pass through by installation: casing inside is divided into upper and lower two chambers by benchmark base plate 8 (shown in Fig. 4), the chamber on top is divided into again two parts in left and right, one of them part is sample standing groove, another part is held dyeing apparatus, the accurate liquid volume added control device of chamber housing chamber housing and the automatically controlled servicing unit of below.Wherein, as shown in Figures 4 and 5, application of sample part mainly be take sample standing groove 19 as the main mechanical full wind-up device 5 rotary sample addition devices of dyeing syringe needle 11 dependence that are provided with above its side for application of sample.As shown in Figure 3 and Figure 5, dyeing apparatus comprises dyeing kettle body 8, dyeing kettle body 8 upper caps have dyeing pot cover 3, in dyeing kettle body 8 inside, be provided with dyeing centrifugal pan 10, dyeing centrifugal pan 10 belows are provided with the dyeing of rotary power main drive gear 7 are provided, and above the side of dyeing centrifugal pan 10, are provided with for the syringe needle that dyes; As shown in Figure 6, other device comprises accurate quantitative liquid feeding apparatus 13 and the automatically controlled servicing unit of microcomputer, wherein, precisely quantitative liquid feeding apparatus 13 comprises wherein, precisely quantitative liquid feeding apparatus 13 comprises mounting bracket 30 and is positioned at 7 membrane pumps and 1 the three-way solenoid valve formation on mounting bracket, membrane pump output terminal distributes and is connected with the liquid filling syringe needle 11 on mechanical full wind-up device, is provided with the microcomputer circuit controller of the accurate quantitative liquid feeding apparatus work of control in a side of mounting bracket; Liquid feed device comprises a plurality of liquid transfer systems that consist of complete machine the external fluid storage tanks of port and waste liquid recycling can.
Automatically controlled servicing unit is for each unit module of complete machine provides the CPU central processing system of accurate instruction, comprises dyeing apparatus, the accurate action command of quantitative liquid feeding apparatus, mechanical full wind-up.
Principle of work or technology are decomposed (eight) patent of the present invention by workflow implementation step in this explanation, realization has designed the equipment of a kind of full automatic collection application of sample, film-making and dyeing integration, complete in a machine from being loaded onto the whole process of dyeing, this whole process is continuous, only need after artificial setting the programming Control program by setting just can robotization complete operation flow process, without other manual operation, without extra manual intervention.Solution is for the shortcoming that the detecting instrument robotization existing in liquid basal cell detection field is not high, process is loaded down with trivial details, waste time and energy.
The beneficial effects of the utility model are: 1, saved time and manpower, greatly improved film-making dyeing efficiency;
2, microcomputer control criterionization operation, reduces personal error, has improved liquid base film-making dyeing quality, is convenient to mass disposal sample, is especially convenient to clinical diagnosis and the examination of extensive anti-cancer generaI investigation and large-scale training, general hospital;
3, realized the systematicness of application of sample, centrifugal, film-making, dyeing, centre is put and is kept without personnel, made liquid base smear steady quality, eucaryotic cell structure be complete, be evenly distributed, and being especially convenient to clinical diagnosis and the examination of extensive anti-cancer generaI investigation and large-scale training, general hospital.
The above, be only embodiment of the present utility model, but protection domain of the present utility model is not limited to this, and any variation of expecting without creative work or replacement, within all should being encompassed in protection domain of the present utility model.Therefore, protection domain of the present utility model should be as the criterion with the protection domain that claims were limited.
Claims (5)
1. a microcomputerized control liquid-based cell sample manufacturing coloring system, it is characterized in that: this film-making coloring system comprises casing and is positioned at the dyeing apparatus of casing inside, machinery full wind-up device, accurate quantitative liquid feeding apparatus and automatically controlled servicing unit, described casing comprises main body, be positioned at the rear shrouding and the dyeing pot cover that is positioned at main body top at main body rear, above main body front, be provided with display operation screen, described casing inside is divided into by a benchmark base plate, lower chambers, described upper chamber is divided into again a left side, right half, left part is divided into sample place position, right part is divided into and holds dyeing apparatus, the accurate liquid volume added control device of chamber housing and the automatically controlled servicing unit that hold dyeing apparatus below, described casing upper right end is provided with application of sample storehouse,
Dyeing apparatus comprises dyeing kettle body, dyeing kettle body upper cap has dyeing kettle body lid, at dyeing pot nside, be provided with dyeing centrifugal pan, dyeing dish below is provided with the dyeing of rotary power main drive gear is provided, above the side of dyeing centrifugal pan, be provided with the dyeing syringe needle for the liquid feeding that dyes, this dyeing syringe needle one side is provided with a rinse bath, and a preparation bin is installed in the draw-in groove of described dyeing centrifugal pan;
Precisely quantitative liquid feeding apparatus comprises power control unit and liquid feed device, wherein, power control unit comprises mounting bracket and is positioned at 7 membrane pumps and 1 the three-way solenoid valve formation on mounting bracket, membrane pump output terminal distributes and is connected with the liquid filling syringe needle on mechanical full wind-up device, a side at mounting bracket is provided with the microcomputer circuit controller of controlling accurate quantitative liquid feeding apparatus work, and liquid feed device comprises a plurality of liquid transfer systems that consist of complete machine the external fluid storage tanks of port and waste liquid recycling can;
Automatically controlled servicing unit is for each unit module of complete machine provides the CPU central processing system of accurate instruction, comprises dyeing apparatus, the accurate action command of quantitative liquid feeding apparatus, mechanical full wind-up.
2. microcomputerized control liquid-based cell sample manufacturing coloring system according to claim 1, is characterized in that: described main body covers front, the He Liangge side, bottom surface of casing.
3. microcomputerized control liquid-based cell sample manufacturing coloring system according to claim 1, it is characterized in that: the lower end of described dyeing centrifugal pan is provided with a motor shaft bearing sleeve, the lower end of this motor shaft bearing sleeve connects a shaft coupling, described shaft coupling be motor fixing seat, the lower end of described motor fixing seat is rotary power motor, and described shaft coupling is connected with the rotary power motor of lower end through motor fixing seat.
4. microcomputerized control liquid-based cell sample manufacturing coloring system according to claim 1, is characterized in that: described preparation bin comprises a photo making cup, microslide and film-making base.
5. microcomputerized control liquid-based cell sample manufacturing coloring system according to claim 1, is characterized in that: described mechanical full wind-up device comprises one first motor, first, second guide shaft, the second motor, synchronizing wheel and central shaft.
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| CN201420303599.1U CN203908840U (en) | 2014-06-09 | 2014-06-09 | Microcomputer-controlled liquid-based cell sheet preparation dyeing system |
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| CN201420303599.1U CN203908840U (en) | 2014-06-09 | 2014-06-09 | Microcomputer-controlled liquid-based cell sheet preparation dyeing system |
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| CN106018045A (en) * | 2016-07-04 | 2016-10-12 | 邱加伟 | Pipetting mechanism for sectioning and staining cells |
| CN106323844A (en) * | 2016-10-31 | 2017-01-11 | 杭州昕龙医疗科技有限公司 | Sample microscopic analysis device |
| CN112113822A (en) * | 2019-06-21 | 2020-12-22 | 深圳迈瑞生物医疗电子股份有限公司 | Biological sample dyeing device, push piece dyeing machine and biological sample dyeing method |
| WO2020257963A1 (en) * | 2019-06-24 | 2020-12-30 | 深圳迈瑞生物医疗电子股份有限公司 | Spreader and sample staining method |
| CN112268773A (en) * | 2020-11-11 | 2021-01-26 | 吉林万方医疗科技有限公司 | Liquid-based cell full-automatic sheet making machine |
| CN112414826A (en) * | 2020-12-04 | 2021-02-26 | 中国人民解放军陆军军医大学第二附属医院 | Smear dyeing machine |
| CN112504796A (en) * | 2020-12-04 | 2021-03-16 | 中国人民解放军陆军军医大学第二附属医院 | Integrated cell treatment device |
| CN112747989A (en) * | 2020-12-23 | 2021-05-04 | 山东骏腾医疗科技有限公司 | Automatic dyeing box for tissue slice |
| CN113624576A (en) * | 2021-08-03 | 2021-11-09 | 深路医学科技(武汉)有限公司 | Semi-automatic liquid-based cell pelleter |
| CN115144247A (en) * | 2022-09-02 | 2022-10-04 | 深圳明灏生物科技有限公司 | Smear device for liquid-based thin-layer cell detection |
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2014
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