CN205749067U - Full Automatic Liquid based thin-layer cell slide-making staining machine - Google Patents
Full Automatic Liquid based thin-layer cell slide-making staining machine Download PDFInfo
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- CN205749067U CN205749067U CN201620696162.8U CN201620696162U CN205749067U CN 205749067 U CN205749067 U CN 205749067U CN 201620696162 U CN201620696162 U CN 201620696162U CN 205749067 U CN205749067 U CN 205749067U
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- liquid
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Abstract
This utility model relates to a kind of Full Automatic Liquid based thin-layer cell slide-making staining machine, it includes frame, the setting-out district being located on framework platform, the pipetting device being located in setting-out district, the producer agency being located at setting-out district side and dyeing mechanism.The purpose of this utility model is to provide a kind of Full Automatic Liquid based thin-layer cell slide-making staining machine.The utility model has the advantage of: 1. border circular areas formed by producer agency intersects or tangent with setting-out district, pipetting device is arranged on setting-out district circle centre position, have only to just to complete sampling, liquid feeding by a pipetting device, clean and draw the operations such as waste liquid, simplify complete machine structure, save manufacturing cost.2. pipetting device arranges cleaning assembly A, can be rinsed the inner tubal wall of inner suction pipe, and is also arranged with trocar sheath on inner suction pipe, and the outer tube wall of inner suction pipe can be rinsed by matching purge assembly B, reaches the effect preventing polluting.
Description
Technical field
This utility model relates to a kind of Full Automatic Liquid based thin-layer cell slide-making staining machine.
Background technology
In medical science detection and biological study, often need by cell sample is carried out film-making and dyeing, in order to more preferably
Ground is observed.Traditional film-making dyeing course all uses manual operations, but owing to manual smear also exists substantial amounts of cell accumulation
And the interference factor such as erythrocyte, mucus, impurity and affect correct diagnosis, it may appear that the false negative rate of 2%～50%, and holding
Easily make diagnostic personnel eye work fatigue, and waste time and energy, the problems such as efficiency is low.In recent years, the application that liquid basal cell learns a skill makes
It is that a kind of cell that is saved in by exfoliative cyte preserves that the film-making of cell and staining technique have had new breakthrough, liquid basal cell to learn a skill
In liquid, can effectively dispel the interference diagnosis factors such as erythrocyte, mucus, impurity and by cell mass dispersion dissociation, significantly change pathology
Cytology's slice-making quality, cellularity and clear background, beneficially Differential Diagnosis, hence it is evident that reduce false negative rate.
Pelleter in the market have the disadvantage that 1. before, during and after sample film-making whole process need operator with
The collaborative operation of step, operates cumbersome efficiency low；2. dyeing course must be completed by manual operation, anthropic factor impact dye easily occurs
Chromaticness amount.
Summary of the invention
The purpose of this utility model is to provide a kind of Full Automatic Liquid based thin-layer cell slide-making staining machine.
The purpose of this utility model is achieved through the following technical solutions: a kind of Full Automatic Liquid based thin-layer cell film-making dyeing dress
Putting, it includes frame, the setting-out district being located on framework platform, the pipetting device being located in setting-out district, be located at setting-out district side
Producer agency and dyeing mechanism；Described producer agency includes centrifugal pan and some dress liquid set up separately on centrifugal pan outer circumferential side
Film-making assembly；Described setting-out district includes some spaced sample wells, and described sample well is annular point centered by pipetting device
Cloth；Formed by described producer agency, border circular areas intersects or tangent with setting-out district；Described pipetting device includes being located at setting-out district
The vertical rotating axle of circle centre position, it is located at the lateral rotation arm of rotary shaft upper end and is located at the shifting liquid group of cursor outboard end
Part, described shifting liquid assembly just to various kinds sample wells or dress liquid film-making assembly directly over.
For prior art, the utility model has the advantage of:
1. border circular areas formed by producer agency intersects or tangent with setting-out district, and pipetting device is arranged on the center of circle, setting-out district
Place, it is only necessary to just can complete sampling, liquid feeding by a pipetting device, clean and draw the operations such as waste liquid, simplify complete machine
Structure, saves manufacturing cost.
2. pipetting device arranges cleaning assembly A, can be rinsed the inner tubal wall of inner suction pipe, and the most sheathed on inner suction pipe
There are trocar sheath, matching purge assembly B, the outer tube wall of inner suction pipe can be rinsed, reach the effect preventing polluting.
3. the cannelure top of pipetting device is provided with liquid storage cylinder, is once concentrated cleanout fluid by liquid storage cylinder, can make
Obtain cannelure full cleanout fluid suitable for reading, when cleanout fluid flows downwardly into cannelure, can carry out rushing without dead angle to inner suction pipe outer wall
Wash.
4. each dyeing liquor conveying pipe is arranged on same fixed support, not only simplifies structure, save machine cost, and
It is easy to the programme-control of producer agency.
Accompanying drawing explanation
Fig. 1 is the stereochemical structure signal of this utility model a kind of Full Automatic Liquid based thin-layer cell slide-making staining machine embodiment
Figure.
Fig. 2 is the structural representation at another visual angle of Full Automatic Liquid based thin-layer cell slide-making staining machine.
Fig. 3 is the top view of Full Automatic Liquid based thin-layer cell slide-making staining machine.
Fig. 4 is the A-A sectional view in Fig. 3.
Fig. 5 is zoomed-in view at A in Fig. 4.
Fig. 6 is the structural representation of pipetting device.
Fig. 7 is the structural representation of dyeing mechanism.
Label declaration: 1 frame, 11 framework platforms, 2 setting-out districts, 21 sample wells, 3 pipetting devices, 30 drive motors, 31 turns
Pipe, 36 cleaning assembly A, 361 reserving liquid tanks, 362 cleanout fluid are put in moving axis, 32 cursors, 33 inner suction pipes, 34 suction tapping assemblies, 341 suctions
Conveying pipe, 363 check valves, 37 trocar sheaths, 371 cannelures, 372 liquid storage cylinders, 373 helical ducts, 38 cleaning assembly B, 39 constant speed
Module, 4 producer agencies, 41 centrifugal pans, 42 dress liquid film-making assemblies, 5 dyeing mechanisms, 51 fixed supports, 52 dyeing liquors conveying pipe, 53
Dyeing liquor case, 6 collection hole, 7 flow pumps.
Detailed description of the invention
Below in conjunction with Figure of description and embodiment, this utility model content is described in detail:
As Fig. 1 to 7 show the reality of a kind of Full Automatic Liquid based thin-layer cell slide-making staining machine that this utility model provides
Execute illustration to be intended to.
A kind of Full Automatic Liquid based thin-layer cell slide-making staining machine, it includes frame 1, the setting-out being located on framework platform 11
District 2, the pipetting device 3 being located in setting-out district 2, the producer agency 4 being located at setting-out district 2 side and dyeing mechanism 5；
Described producer agency 4 includes centrifugal pan 41 and some dress liquid film-making assemblies set up separately on centrifugal pan 41 outer circumferential side
42；Described setting-out district 2 includes some spaced sample wells 21, and described sample well 21 is annular point centered by pipetting device 3
Cloth；Border circular areas formed by described producer agency 4 intersects or tangent with setting-out district 2, setting-out district 2 and producer agency 4 cross-shaped portion
Divide and be not provided with sample well 21, i.e. various kinds sample wells 21 interval arranges the arcuate structure formed centered by pipetting device 3.
Producer agency 4 sees earlier patent application: Thinprep pap test pelletizer, application number: 201510422833.1.
Described pipetting device 3 includes being located at the vertical rotating axle 31 of setting-out district 2 circle centre position, being located at rotary shaft 31 upper end
Lateral rotation arm 32 and be located at the shifting liquid assembly of cursor 32 outboard end, described shifting liquid assembly is just to various kinds sample wells 21 or dress liquid
Directly over film-making assembly 42.
Move liquid assembly to be driven around setting-out district 2 center rotating by rotary shaft 31, just turn to sample well 21 when moving liquid assembly
During top, can sample in pipette samples hole 21；
When moving liquid assembly and turning to setting-out district 2 with producer agency's 4 intersecting area, move liquid assembly just to dress liquid film-making assembly
Directly over 42, the sample of absorption can be put to dress liquid film-making assembly 42 or draw the waste liquid in dress liquid film-making assembly 42.
In described setting-out district 2, at least a sample well 21 is the collection hole 6 for collecting waste liquid or cleanout fluid.Collect
Hole 6 is connected with waste liquid cylinder.
When moving liquid assembly and turning to collect directly over hole 6, cleanout fluid is also drained in collection hole 6 by shifting liquid assembly capable of washing
Or the waste liquid drawn in dress liquid film-making assembly 42 is drained in collection hole 6.
Described shifting liquid assembly includes that vertically arranged inner suction pipe 33 and the suction being connected with inner suction pipe 33 upper orifice respectively are put
Liquid assembly 34 and cleaning assembly A36；
Described suction tapping assembly 34 is used for the sample on pipette samples hole 21 and transfers them to fill liquid film-making assembly 42
Or for drawing the waste liquid on dress liquid film-making assembly 42；Described cleaning assembly A36 is for cleaning the inner tubal wall of inner suction pipe 33.
Described cleaning assembly A36 includes the reserving liquid tank 361 for store washing liquid, is connected to inner suction pipe 33 and reserving liquid tank
Cleaning fluid conveying pipeline 362 between 361 and flow pumps, described cleaning fluid conveying pipeline 362 arranges check valve 363.Check valve
363 are disposed to prevent from inhaling when tapping assembly 34 draws waste liquid or sample liquid pollute the cleanout fluid in reserving liquid tank 361.
Described cleanout fluid is distilled water.
Described suction tapping assembly 34 includes inhaling puts pipe 341 and the flow pumps of band function of measuring.
Described inner suction pipe 33 upper orifice, pipe 341 is put in suction and cleaning fluid conveying pipeline 362 is connected by tee T.
Move liquid assembly when pipette samples or waste liquid, the inside and outside tube wall of inner suction pipe 33 all can residual contaminants, therefore need
The inside and outside tube wall of inner suction pipe 33 is cleaned simultaneously, can be only achieved the effect preventing polluting.
Described shifting liquid assembly also includes the trocar sheath 37 being set in inner suction pipe 33 outer wall top and is connected with trocar sheath 37
Cleaning assembly B38；
Trocar sheath 37 upper portion inner tube wall is tightly placed on inner suction pipe 33 outer wall, outside trocar sheath 37 bottom inner tubal wall is with inner suction pipe 33
Leaving gap between wall and form cannelure 371, cannelure 371 top is connected with cleaning assembly B38.
Described cannelure 371 top is provided with liquid storage cylinder 372, and described liquid storage cylinder 372 is in funnel-form.
When cleaning assembly B38 carries cleanout fluid in liquid storage cylinder 372, owing to the feed liquor speed of liquid storage cylinder 372 is more than
Liquid speed, short time cleaning liquid inside is concentrated in liquid storage cylinder 372, when cleaning assembly B38 stops conveying, in liquid storage cylinder 372
Cleanout fluid can flow downwardly in cannelure 371, and inner suction pipe 33 outer wall is rinsed.
By liquid storage cylinder 372, cleanout fluid is once concentrated, cannelure 371 full cleanout fluid suitable for reading can be made, when clearly
When washing liquid flows downwardly into cannelure 371, inner suction pipe 33 outer wall can be carried out the flushing without dead angle.
The liquid storage cylinder 372 of funnel-shaped structure can increase cleanout fluid flushing pressure.
Cleaning assembly B38 is identical with the structure of cleaning assembly A36.
Axial screw passage 373 centered by inner suction pipe 33 is offered in described trocar sheath 37；On described helical duct 373
Portion's connection cleaning assembly B38, its underpart connection liquid storage cylinder 372.
Described rotary shaft 31 lower end is provided with driving motor 30, and described driving motor 30 controls to rise up and down by constant speed module 39
Fall.
When driving motor 30 to drive shifting liquid assembly to turn to directly over sample well 21 or dress liquid film-making assembly 42, constant speed mould
Group 39 control moves in liquid assembly drops to sample well 21 or dress liquid film-making assembly 42 and carries out imbibition or tapping, then constant speed module 39
Control to move liquid assembly and rise reset.
Motor 30 is driven to be arranged on the downside of framework platform 11.
Described constant speed module 39 includes vertically arranged screw rod and the sliding shoe coordinated with screw flight, described sliding shoe
Motor 30 is fixing to be connected with driving, and when screw rod rotates, sliding shoe drives and drives motor 30 to carry out oscilaltion campaign.
Described dyeing mechanism 5 includes that the fixed support 51 being located on framework platform 11 and some being respectively used to carry difference
The dyeing liquor conveying assembly of dyeing liquor；
The dye that each dyeing liquor conveying assembly includes the dyeing liquor case 53 for storing dyeing liquor, is connected on dyeing liquor case 53
Color liquid conveying pipe 52 and flow pumps；The liquid outlet of each dyeing liquor conveying pipe 52 is located on fixed support 51, and its lower nozzle is just
Above same dress liquid film-making assembly 42.
The liquid outlet of dyeing liquor conveying pipe 52 is vertically arranged, and the liquid outlet tube wall of each dyeing liquor conveying pipe 52 is against formation
Drain pipe group.
In the present embodiment, it is provided with four groups of dyeing liquor conveying assemblies altogether according to the colouring method used, is respectively used to conveying
Ethanol, A liquid, B liquid and C liquid.Each dyeing liquor conveying pipe 52 is arranged on same fixed support 51, not only simplifies structure, joint
Save machine cost, and be easy to the programme-control of producer agency 4.
Work process:
One. sampling
Driving motor 30 to drive inner suction pipe 33 to turn to directly over sample well 21, constant speed module 39 controls inner suction pipe 33 and declines
Stretch in sample well 21, inhale tapping assembly 34 and sample liquid is sucked in inner suction pipe 33；Inner suction pipe 33 rises and turns to the liquid system that fills
Directly over chip module 42, inner suction pipe 33 decline is stretched in dress liquid film-making assembly 42, inhales tapping assembly 34 and sample liquid is put into dress liquid
In film-making assembly 42；Inner suction pipe 33 rises and turns to collect directly over hole 6, and cleaning assembly A36 and cleaning assembly B38 is to interior suction
Inside and outside pipe 33, tube wall is rinsed, and cleanout fluid flows into be collected in hole 6；
Inner suction pipe 33 turns to directly over another sample well 21, and centrifugal pan 41 rotates a working position, repeats above-mentioned sampling
Process.
Two. sample preparation
After having sampled, it is centrifugal that centrifugal pan 41 drives dress liquid film-making assembly 42 to rotate.
Three. dyeing
After centrifugal sample preparation completes, dress liquid film-making assembly 42 is parked in immediately below the drain pipe group of dyeing mechanism 5, and dyeing liquor carries
Assembly adds ethanol in dress liquid film-making assembly 42, and centrifugal pan 41 rotates a working position, repeats above-mentioned ethanol and adds operation.
After having added all of dress liquid film-making assembly 42, it is centrifugal that centrifugal pan 41 drives dress liquid film-making assembly 42 to rotate.
After being centrifuged, motor 30 is driven to drive inner suction pipe 33 to turn to fill directly over liquid film-making assembly 42, constant speed module
39 control inner suction pipe 33 decline stretches in dress liquid film-making assembly 42, inhales tapping assembly 34 and is inhaled by the waste liquid in dress liquid film-making assembly 42
Entering in inner suction pipe 33, inner suction pipe 33 rises and turns to collect directly over hole 6, inhales tapping assembly 34 and will fill in liquid film-making assembly 42
Waste liquid enter in collection hole 6, and by cleaning assembly A36 and cleaning assembly B38, tube wall inside and outside inner suction pipe 33 is rinsed.
After flushing completes, inner suction pipe 33 adds cleanout fluid to dress liquid film-making assembly 42 successively, and centrifugal pan 41 drives dress liquid system
Chip module 42 rotates centrifugal；After being centrifuged, extract waste liquid by inner suction pipe 33；Dyeing liquor conveying assembly is to dress liquid film-making assembly
42 add A liquid, extract waste liquid after being centrifuged；Inner suction pipe 33 adds cleanout fluid to dress liquid film-making assembly 42, extracts waste liquid after being centrifuged；Dye
Color liquid conveying assembly adds ethanol to dress liquid film-making assembly 42, extracts waste liquid after being centrifuged；Dyeing liquor conveying assembly is to dress liquid film-making
Assembly 42 adds B liquid, extracts waste liquid after being centrifuged；Inner suction pipe 33 adds cleanout fluid to dress liquid film-making assembly 42, and after being centrifuged, extraction is useless
Liquid；Dyeing liquor conveying assembly adds C liquid to dress liquid film-making assembly 42, completes dying operation.
Claims (10)
1. a Full Automatic Liquid based thin-layer cell slide-making staining machine, it is characterised in that: it include frame (1), be located at frame put down
Setting-out district (2) on platform (11), the pipetting device (3) being located in setting-out district (2), the producer agency that is located at setting-out district (2) side
(4) and dyeing mechanism (5)；
Described producer agency (4) includes centrifugal pan (41) and some dress liquid film-making groups set up separately on centrifugal pan (41) outer circumferential side
Part (42)；Described setting-out district (2) includes some spaced sample wells (21), and described sample well (21) is with pipetting device (3)
Centered by annular spread；Formed by described producer agency (4), border circular areas intersects or tangent with setting-out district (2)；
Described pipetting device (3) includes being located at the vertical rotating axle (31) of setting-out district (2) circle centre position, being located at rotary shaft (31) upper end
The lateral rotation arm (32) in portion and be located at the shifting liquid assembly of cursor (32) outboard end, described shifting liquid assembly is just to various kinds sample wells
(21) or directly over dress liquid film-making assembly (42).
Full Automatic Liquid based thin-layer cell slide-making staining machine the most according to claim 1, it is characterised in that: described shifting liquid group
Part includes vertically arranged inner suction pipe (33) and suction tapping assembly (34) being connected respectively and clear with inner suction pipe (33) upper orifice
Wash assembly A (36)；
Described suction tapping assembly (34) is used for the sample on pipette samples hole (21) and transfers them to fill liquid film-making assembly (42)
Go up or be used for drawing the waste liquid on dress liquid film-making assembly (42)；Described cleaning assembly A (36) is used for cleaning inner suction pipe (33)
Inner tubal wall.
Full Automatic Liquid based thin-layer cell slide-making staining machine the most according to claim 2, it is characterised in that: described cleaning group
Part A (36) include the reserving liquid tank (361) for store washing liquid, be connected between inner suction pipe (33) and reserving liquid tank (361) clear
Washing liquid conveying pipe (362) and flow pumps, described cleaning fluid conveying pipeline (362) arranges check valve (363).
Full Automatic Liquid based thin-layer cell slide-making staining machine the most according to claim 2, it is characterised in that: described shifting liquid group
Part also includes the trocar sheath (37) being set in inner suction pipe (33) outer wall top and the cleaning assembly B being connected with trocar sheath (37)
(38)；
Trocar sheath (37) upper portion inner tube wall is tightly placed on inner suction pipe (33) outer wall, trocar sheath (37) bottom inner tubal wall and inner suction pipe
(33) leaving gap between outer wall and form cannelure (371), cannelure (371) top is connected with cleaning assembly B (38).
Full Automatic Liquid based thin-layer cell slide-making staining machine the most according to claim 4, it is characterised in that: described cannelure
(371) top is provided with liquid storage cylinder (372), and described liquid storage cylinder (372) is in funnel-form.
Full Automatic Liquid based thin-layer cell slide-making staining machine the most according to claim 5, it is characterised in that: described trocar sheath
(37) axial screw passage (373) centered by inner suction pipe (33) is offered in；The connection of described helical duct (373) top is cleaned
Assembly B (38), its underpart connection liquid storage cylinder (372).
Full Automatic Liquid based thin-layer cell slide-making staining machine the most according to claim 1, it is characterised in that: described rotary shaft
(31) lower end is provided with driving motor (30), and described driving motor (30) controls oscilaltion by constant speed module (39).
Full Automatic Liquid based thin-layer cell slide-making staining machine the most according to claim 1, it is characterised in that: described setting-out district
(2) in, at least a sample well (21) is the collection hole (6) for collecting waste liquid or cleanout fluid.
9. according to the Full Automatic Liquid based thin-layer cell slide-making staining machine described in claim 1-8 any one, it is characterised in that:
Described dyeing mechanism (5) includes that the fixed support (51) being located on framework platform (11) and some being respectively used to carry different dye
The dyeing liquor conveying assembly of color liquid；Each dyeing liquor conveying assembly includes the dyeing liquor case (53) for storing dyeing liquor, is connected to
Dyeing liquor conveying pipe (52) and flow pumps on dyeing liquor case (53)；The liquid outlet of each dyeing liquor conveying pipe (52) is located at fixing
On support (51), and its lower nozzle is just to same dress liquid film-making assembly (42) top.
Full Automatic Liquid based thin-layer cell slide-making staining machine the most according to claim 9, it is characterised in that: described dyeing
The liquid outlet of liquid conveying pipe (52) is vertically arranged, and the liquid outlet tube wall of each dyeing liquor conveying pipe (52) is against forming drain pipe
Group.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620696162.8U CN205749067U (en) | 2016-07-04 | 2016-07-04 | Full Automatic Liquid based thin-layer cell slide-making staining machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620696162.8U CN205749067U (en) | 2016-07-04 | 2016-07-04 | Full Automatic Liquid based thin-layer cell slide-making staining machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205749067U true CN205749067U (en) | 2016-11-30 |
Family
ID=57380786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620696162.8U Withdrawn - After Issue CN205749067U (en) | 2016-07-04 | 2016-07-04 | Full Automatic Liquid based thin-layer cell slide-making staining machine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205749067U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106018033A (en) * | 2016-07-04 | 2016-10-12 | 邱加伟 | Fully automatic thinprep cytology processing and dyeing device |
| CN109507004A (en) * | 2018-11-21 | 2019-03-22 | 杭州海世嘉生物科技有限公司 | A kind of natural subsidence sectioning cells dyeing work station control method and system |
-
2016
- 2016-07-04 CN CN201620696162.8U patent/CN205749067U/en not_active Withdrawn - After Issue
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106018033A (en) * | 2016-07-04 | 2016-10-12 | 邱加伟 | Fully automatic thinprep cytology processing and dyeing device |
| CN109507004A (en) * | 2018-11-21 | 2019-03-22 | 杭州海世嘉生物科技有限公司 | A kind of natural subsidence sectioning cells dyeing work station control method and system |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20161130 Effective date of abandoning: 20190611 |