CN1985595A - Germicide containing thiophanate-methyl and prochloraz - Google Patents
Germicide containing thiophanate-methyl and prochloraz Download PDFInfo
- Publication number
- CN1985595A CN1985595A CN 200610098368 CN200610098368A CN1985595A CN 1985595 A CN1985595 A CN 1985595A CN 200610098368 CN200610098368 CN 200610098368 CN 200610098368 A CN200610098368 A CN 200610098368A CN 1985595 A CN1985595 A CN 1985595A
- Authority
- CN
- China
- Prior art keywords
- prochloraz
- methyl
- thiophanate
- germicide
- bactericide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000005820 Prochloraz Substances 0.000 title claims abstract description 23
- TVLSRXXIMLFWEO-UHFFFAOYSA-N prochloraz Chemical compound C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl TVLSRXXIMLFWEO-UHFFFAOYSA-N 0.000 title claims abstract description 23
- 239000005842 Thiophanate-methyl Substances 0.000 title claims description 24
- QGHREAKMXXNCOA-UHFFFAOYSA-N thiophanate-methyl Chemical compound COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC QGHREAKMXXNCOA-UHFFFAOYSA-N 0.000 title claims description 24
- 230000002070 germicidal effect Effects 0.000 title abstract 5
- 230000000844 anti-bacterial effect Effects 0.000 claims description 13
- 239000003899 bactericide agent Substances 0.000 claims description 11
- 239000000203 mixture Substances 0.000 claims description 8
- 239000012752 auxiliary agent Substances 0.000 claims description 6
- 239000000945 filler Substances 0.000 claims description 6
- 239000004615 ingredient Substances 0.000 claims description 2
- 241000209094 Oryza Species 0.000 abstract description 11
- 235000007164 Oryza sativa Nutrition 0.000 abstract description 11
- 235000009566 rice Nutrition 0.000 abstract description 11
- 241000209140 Triticum Species 0.000 abstract description 10
- 235000021307 Triticum Nutrition 0.000 abstract description 10
- 238000012360 testing method Methods 0.000 abstract description 8
- 206010039509 Scab Diseases 0.000 abstract description 7
- 239000000126 substance Substances 0.000 abstract description 2
- 230000001276 controlling effect Effects 0.000 abstract 2
- 230000003405 preventing effect Effects 0.000 abstract 2
- 239000003814 drug Substances 0.000 description 9
- 238000012545 processing Methods 0.000 description 6
- 239000002131 composite material Substances 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 230000001018 virulence Effects 0.000 description 4
- 238000009736 wetting Methods 0.000 description 4
- 241000223195 Fusarium graminearum Species 0.000 description 3
- 241001330975 Magnaporthe oryzae Species 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 229910021380 Manganese Chloride Inorganic materials 0.000 description 2
- 239000003905 agrochemical Substances 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
- 229940099607 manganese chloride Drugs 0.000 description 2
- 239000011565 manganese chloride Substances 0.000 description 2
- OXOKTPUZOHPXSA-UHFFFAOYSA-L manganese(2+);n-propyl-n-[2-(2,4,6-trichlorophenoxy)ethyl]imidazole-1-carboxamide;dichloride Chemical compound Cl[Mn]Cl.C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl.C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl.C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl.C1=CN=CN1C(=O)N(CCC)CCOC1=C(Cl)C=C(Cl)C=C1Cl OXOKTPUZOHPXSA-UHFFFAOYSA-L 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000003595 mist Substances 0.000 description 2
- 235000010603 pastilles Nutrition 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 238000007747 plating Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 235000014347 soups Nutrition 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- TWFZGCMQGLPBSX-UHFFFAOYSA-N Carbendazim Natural products C1=CC=C2NC(NC(=O)OC)=NC2=C1 TWFZGCMQGLPBSX-UHFFFAOYSA-N 0.000 description 1
- 239000006013 carbendazim Substances 0.000 description 1
- JNPZQRQPIHJYNM-UHFFFAOYSA-N carbendazim Chemical compound C1=C[CH]C2=NC(NC(=O)OC)=NC2=C1 JNPZQRQPIHJYNM-UHFFFAOYSA-N 0.000 description 1
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- DQJCHOQLCLEDLL-UHFFFAOYSA-N tricyclazole Chemical compound CC1=CC=CC2=C1N1C=NN=C1S2 DQJCHOQLCLEDLL-UHFFFAOYSA-N 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention belongs to the field of farm chemical technology, and is especially a kind of germicide for preventing and controlling wheat scab and rice blast. The germicide of the present invention contains thiopanate-methyl and prochloraz in the weight ratio of 3-11 as the effective components and accounting for 5-60 wt% of the germicide. It contains also conventional assistant in 5-10 wt% and stuffing for the rest. Test shows that the germicide of the present invention has obvious wheat scab and rice blast preventing and controlling effect.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of bactericide that is used to prevent and treat wheat scab and rice blast.
Background technology
Wheat scab winter wheat district, the middle and lower reach of Yangtze River and northeast spring wheat district rainy in the fringe phase, that have a humid climate take place seriously also often to take place at other Mai Qu, cause that loss is bigger.Since at present large tracts of land produce go up plantation be mainly susceptible or in anti-kind, chemical control is still the important means of control head blight.This sick medicament of control is based on carbendazim etc. in the production, and pesticide resistance has appearred in use all the year round.Rice blast is one of main disease on China paddy rice, takes place throughout the year, loses bigger.It is longer that large tracts of land is produced the time limit of going up the main medicament use that prevents and treats rice blast, promoted the history in so far existing more than 20 year in nineteen eighty-two in China's large tracts of land as tricyclazole, exists the risk that develops immunity to drugs.
Summary of the invention
Technical problem to be solved by this invention provides a kind of bactericide that contains thiophanate-methyl and Prochloraz that can better prevent and treat wheat scab and rice blast.
The bactericide that contains thiophanate-methyl and Prochloraz of the present invention, its effective ingredient are thiophanate-methyl and Prochloraz, and the thiophanate-methyl that comprises in its composition and the weight ratio of Prochloraz are 3: 1～11: 1.Also can include conventional auxiliary agent and filler in its composition, wherein thiophanate-methyl and Prochloraz account for 5%～60% of bactericide gross weight altogether, and auxiliary agent accounts for 5%～10% of bactericide gross weight, and all the other are filler.
Bactericide of the present invention has remarkable prevention effect through actual test to wheat scab and rice blast.
Embodiment
Embodiment one～embodiment five:
Embodiments of the invention one～embodiment five carries out composite according to 3: 1,5: 1,7: 1,9: 1 and 11: 1 five kinds of weight ratios thiophanate-methyl and Prochloraz respectively.
Above-mentioned five embodiment are carried out indoor measurement to the inhibitory action of fusarium graminearum.Growth rate method is adopted in test, earlier each proportioning is made into the series concentration gradient.It is standby the fusarium graminearum diameter after secondary separation is cultivated to be that the aseptic card punch of 0.5CM goes out to punch in the bacterium colony leading edge, moves then on pastille PDA plating medium, places in 25 ± 1 ℃ of incubators and cultivates, and cultivates and measures colony diameter after 6 days.Every processing repeats 6 times.Measured result is calculated antibacterial percentage compared with the control.5 proportionings are carried out the synergy test by the synergy test method.Calculate the mixture of 5 proportionings and the IC of 2 single agent
50Value is calculated co-toxicity coefficient, judges whether to have synergistic effect.Criterion be co-toxicity coefficient significantly greater than 100 for synergy, less than 100 be antagonism, equaling 100 is addition.Concentration and co-toxicity coefficient result such as table one in the virulence regression equation of the thiophanate-methyl that is obtained, Prochloraz and composite comparison fusarium graminearum, the inhibition:
Table one
| Medicament (thiophanate-methyl: Prochloraz) | Virulence regression equation | LC 50(mg/kg) | Co-toxicity coefficient | |
| 1∶0 | y＝0.9771x+3.9692 | 11.34902 | ||
| 0∶1 | y＝0.9874x+6.4321 | 0.03545 | ||
| Embodiment one | 3∶1 | y＝0.9106x+6.0766 | 0.06572 | 213.76073 |
| Embodiment two | 5∶1 | y＝0.9453x+5.9758 | 0.09284 | 225.58066 |
| Embodiment three | 7∶1 | y＝0.8501x+5.6676 | 0.16394 | 169.28849 |
| Embodiment four | 9∶1 | y＝0.6938x+5.3735 | 0.28951 | 119.10016 |
| Embodiment five | 11∶1 | y＝0.7536x+5.2951 | 0.40589 | 101.32523 |
Embodiment six～embodiment ten:
Embodiments of the invention six～embodiment ten carries out composite according to 3: 1,5: 1,7: 1,9: 1 and 11: 1 five kinds of weight ratios thiophanate-methyl and Prochloraz respectively.
Above-mentioned five embodiment are carried out indoor measurement to the inhibitory action of Pyricularia oryzae.Growth rate method is adopted in test, earlier each proportioning is made into the series concentration gradient.It is standby the Pyricularia oryzae diameter after secondary separation is cultivated to be that the aseptic card punch of 0.5CM goes out to punch in the bacterium colony leading edge, moves then on pastille PDA plating medium, places in 25 ± 1 ℃ of incubators and cultivates, and cultivates and measures colony diameter after 8 days.Every processing repeats 6 times.Measured result is calculated antibacterial percentage compared with the control.5 proportionings are carried out the synergy test by the synergy test method.Calculate the mixture of 5 proportionings and the IC of 2 single agent
50Value is calculated co-toxicity coefficient, judges whether to have synergistic effect.Criterion be co-toxicity coefficient significantly greater than 100 for synergy, less than 100 be antagonism, equaling 100 is addition.Concentration and co-toxicity coefficient result such as table two in the virulence regression equation of the thiophanate-methyl that is obtained, Prochloraz and composite comparison Pyricularia oryzae, the inhibition:
Table two
| Medicament (thiophanate-methyl: Prochloraz) | Virulence regression equation | LC 50(mg/kg) | Co-toxicity coefficient | |
| 1∶0 | y＝1.1476x+4.4181 | 3.21409 | ||
| 0∶1 | y＝1.1569x+6.3797 | 0.06418 | ||
| Embodiment six | 3∶1 | y＝0.894x+5.851 | 0.11171 | 216.82072 |
| Embodiment seven | 5∶1 | y＝0.9706x+5.7995 | 0.15007 | 233.30660 |
| Embodiment eight | 7∶1 | y＝1.0351x+5.5929 | 0.26743 | 168.44537 |
| Embodiment nine | 9∶1 | y＝0.9757x+5.3844 | 0.40367 | 134.77094 |
| Embodiment ten | 11∶1 | y＝0.9522x+5.1967 | 0.62148 | 101.60570 |
Embodiment 11:
Carry out composite according to 5: 1 weight ratio thiophanate-methyl and Prochloraz, then itself and auxiliary agent and filler are mixed with fungicide preparation, wherein thiophanate-methyl and Prochloraz account for 42% of total formulation weight amount altogether, auxiliary agent accounts for 5% (wherein surfactant neopelex 2%, wetting agent sodium lignin sulfonate 3%) of total formulation weight amount, and all the other are filler.
The control efficiency of the preparation of embodiment 11 being prevented and treated wheat scab compares test, and method is as follows:
Every mu 40 gram of preparation, 50 grams, 60 grams of embodiment two are set, every mu 10 gram of 50% prochloraz-manganese chloride complex wetting powder, every mu 100 gram of 70% thiophanate-methyl wetting powder and blank totally 6 processing, every processing repeats 3 times, repeat 100 square metres of areas, convert water spray medicine with mist sprayer, 18 kilograms of every mu of soups in the wheat full heading time, the head blight disease index is respectively handled in investigation in 10 days behind the medicine, and calculates relative control efficiency with the disease index of check plot.Its result such as table three:
Table three
| For the examination agricultural chemicals | Consumption (gram/mu) | Control efficiency % |
| Embodiment 11 | 40 | 88.12 |
| 50 | 90.47 | |
| 60 | 95.45 | |
| 70% thiophanate-methyl WP | 100 | 78.59 |
| 50% Prochloraz WP | 10 | 77.85 |
Embodiment 12:
The control efficiency of the preparation of embodiment 11 being prevented and treated rice blast compares test, and method is as follows:
Every mu 40 gram of preparation, 50 grams, 60 grams of embodiment two are set, every mu 10 gram of 50% prochloraz-manganese chloride complex wetting powder, every mu 100 gram of 70% thiophanate-methyl wetting powder and blank totally 6 processing, every processing repeats 3 times, repeat 100 square metres of areas, convert water spray medicine with mist sprayer, 18 kilograms of every mu of soups in the paddy rice full heading time, the rice blast disease index is respectively handled in investigation in 10 days behind the medicine, and calculates relative control efficiency with the disease index of check plot.Its result such as table four:
Table four
| For the examination agricultural chemicals | Consumption (gram/mu) | Control efficiency % |
| Embodiment 11 | 40 | 90.45 |
| 50 | 92.92 | |
| 60 | 96.68 | |
| 70% thiophanate-methyl WP | 100 | 81.25 |
| 50% Prochloraz WP | 10 | 84.38 |
Claims (2)
1, a kind of bactericide that contains thiophanate-methyl and Prochloraz is characterized in that: its effective ingredient is thiophanate-methyl and Prochloraz, and the thiophanate-methyl that comprises in its composition and the weight ratio of Prochloraz are 3: 1～11: 1.
2, the bactericide that contains thiophanate-methyl and Prochloraz according to claim 1, it is characterized in that: also include auxiliary agent and filler in its composition, wherein thiophanate-methyl and Prochloraz account for 5%～60% of bactericide gross weight altogether, auxiliary agent accounts for 5%～10% of bactericide gross weight, and all the other are filler.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100983681A CN100488363C (en) | 2006-12-15 | 2006-12-15 | Germicide containing thiophanate-methyl and prochloraz |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100983681A CN100488363C (en) | 2006-12-15 | 2006-12-15 | Germicide containing thiophanate-methyl and prochloraz |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1985595A true CN1985595A (en) | 2007-06-27 |
| CN100488363C CN100488363C (en) | 2009-05-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006100983681A Expired - Fee Related CN100488363C (en) | 2006-12-15 | 2006-12-15 | Germicide containing thiophanate-methyl and prochloraz |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100488363C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101796955A (en) * | 2009-12-31 | 2010-08-11 | 青岛星牌作物科学有限公司 | Composite bactericidal composite and applications thereof |
| CN101632375B (en) * | 2009-05-27 | 2012-07-04 | 深圳诺普信农化股份有限公司 | Pyricularia amide compound sterilization composition |
| CN106719765A (en) * | 2016-11-28 | 2017-05-31 | 河池市金城江区科学技术情报研究所 | A kind of method for preventing and treating mulberry tree leaf blight |
| CN106922712A (en) * | 2015-12-30 | 2017-07-07 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
-
2006
- 2006-12-15 CN CNB2006100983681A patent/CN100488363C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101632375B (en) * | 2009-05-27 | 2012-07-04 | 深圳诺普信农化股份有限公司 | Pyricularia amide compound sterilization composition |
| CN101796955A (en) * | 2009-12-31 | 2010-08-11 | 青岛星牌作物科学有限公司 | Composite bactericidal composite and applications thereof |
| CN101796955B (en) * | 2009-12-31 | 2013-04-17 | 青岛星牌作物科学有限公司 | Composite bactericidal composite and applications thereof |
| CN106922712A (en) * | 2015-12-30 | 2017-07-07 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
| CN106719765A (en) * | 2016-11-28 | 2017-05-31 | 河池市金城江区科学技术情报研究所 | A kind of method for preventing and treating mulberry tree leaf blight |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100488363C (en) | 2009-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20070627 Assignee: JIANGSU LVDUN PLANT PROTECTION AGROCHEMICAL EXPERIMENTAL Co.,Ltd. Assignor: JIANGSU FOOTHILL ZHENJIANG AGRICULTURE Research Institute Contract record no.: 2010320000228 Denomination of invention: Germicide containing thiophanate-methyl and prochloraz Granted publication date: 20090520 License type: Exclusive License Record date: 20100315 |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090520 |
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| CF01 | Termination of patent right due to non-payment of annual fee |