CN1972644B - 用于骨组织再生的生物可吸收插销式植入体和方法 - Google Patents

用于骨组织再生的生物可吸收插销式植入体和方法 Download PDF

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Publication number
CN1972644B
CN1972644B CN2004800405322A CN200480040532A CN1972644B CN 1972644 B CN1972644 B CN 1972644B CN 2004800405322 A CN2004800405322 A CN 2004800405322A CN 200480040532 A CN200480040532 A CN 200480040532A CN 1972644 B CN1972644 B CN 1972644B
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bolt
type implant
implant
polycaprolactone
cell
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Chinese (zh)
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CN1972644A (zh
Inventor
张瑞兴
陈金清
D·胡特马赫
T·C·林
J-T·车滋
N·朱
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Osteopore International Pte Ltd
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Osteopore International Pte Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0067Three-dimensional shapes conical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Medicinal Chemistry (AREA)
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  • Organic Chemistry (AREA)
CN2004800405322A 2003-11-21 2004-11-22 用于骨组织再生的生物可吸收插销式植入体和方法 Expired - Lifetime CN1972644B (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI720668B (zh) * 2019-10-29 2021-03-01 可成生物科技股份有限公司 頭顱骨植入物

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6730252B1 (en) 2000-09-20 2004-05-04 Swee Hin Teoh Methods for fabricating a filament for use in tissue engineering
EP1691726B1 (en) 2003-11-21 2013-01-16 Osteopore International Pte Ltd Bioabsorbable plug implants
US20060247790A1 (en) * 2005-04-30 2006-11-02 Mckay William F Shaped osteochondral grafts and methods of using same
US7722614B2 (en) * 2006-01-27 2010-05-25 Warsaw Orthopedic, Inc, Osteochondral implant fixation method
US20080125863A1 (en) * 2006-11-28 2008-05-29 Mckay William F Implant designs and methods of improving cartilage repair
WO2008157285A1 (en) 2007-06-13 2008-12-24 Fmc Corporation Biopolymer based implantable degradable devices
JP5320183B2 (ja) * 2008-06-26 2013-10-23 国立大学法人 岡山大学 顎顔面インプラント治療のための骨質検査方法
US8614189B2 (en) * 2008-09-24 2013-12-24 University Of Connecticut Carbon nanotube composite scaffolds for bone tissue engineering
US8702808B2 (en) * 2008-10-17 2014-04-22 Osteopore International Pte Ltd Resorbable scaffolds for bone repair and long bone tissue engineering
FR2939304B1 (fr) * 2008-12-05 2012-03-30 Pierre Sabin Ensemble de boitier-interface destine a etre implante dans une paroi osseuse
US12279964B2 (en) 2008-12-18 2025-04-22 4Web, Llc Implants having bone growth promoting agents and methods of using such implants to repair bone structures
PL2358309T3 (pl) 2008-12-18 2016-04-29 4 Web Inc Implant o strukturze kratownicowej
GB0907064D0 (en) 2009-04-24 2009-06-03 Grampian Health Board Tissue anchor insertion system
US8343225B2 (en) * 2009-06-05 2013-01-01 Linares Medical Devices, Llc Skull patch with durable plastic construction and undercut mount to existing skull perimeter
US20110087274A1 (en) * 2009-10-08 2011-04-14 Tyco Healtcare Group LP, New Haven, Ct Wound Closure Device
US20110087273A1 (en) * 2009-10-08 2011-04-14 Tyco Healthcare Group Lp Wound Closure Device
US9833225B2 (en) * 2009-10-08 2017-12-05 Covidien Lp Wound closure device
US8617206B2 (en) * 2009-10-08 2013-12-31 Covidien Lp Wound closure device
US8858592B2 (en) 2009-11-24 2014-10-14 Covidien Lp Wound plugs
US8444699B2 (en) * 2010-02-18 2013-05-21 Biomet Manufacturing Corp. Method and apparatus for augmenting bone defects
AU2011251991B2 (en) 2010-05-10 2014-05-22 University Of Connecticut Lactoferrin -based biomaterials for tissue regeneration and drug delivery
ITMI20110723A1 (it) * 2011-04-29 2012-10-30 Mako Shark Srl Protesi per cranioplastica e metodo di realizzazione
CN102415922B (zh) * 2011-09-06 2014-01-01 中国人民解放军第四军医大学 一种可控血管化人工骨移植物
CA2873076A1 (en) 2012-05-10 2013-11-14 The Trustees Of The Stevens Institute Of Technology Biphasic osteochondral scaffold for reconstruction of articular cartilage
KR20150015532A (ko) * 2012-05-30 2015-02-10 뉴욕 유니버시티 조직 수복 장치 및 스캐폴드
US12115071B2 (en) 2012-09-25 2024-10-15 4Web, Llc Programmable intramedullary implants and methods of using programmable intramedullary implants to repair bone structures
IN2015DN04046A (enExample) * 2012-11-14 2015-10-02 Orthopaedic Innovation Ct Inc
EP2999492B1 (de) * 2013-05-23 2020-04-08 CeramTec GmbH Implantat aus keramik mit porenkanälen
US10376611B2 (en) * 2015-02-16 2019-08-13 The Royal Institution For The Advancement Of Learning/Mcgill University Multilayered bone graft and method of making same
EP3115025A1 (en) * 2015-07-08 2017-01-11 Skulle Implants OY Orthopedic implant
US11046823B2 (en) 2016-08-03 2021-06-29 Wake Forest University Health Sciences Composition with polymer and ceramic and methods of use thereof
US12031026B2 (en) 2016-08-03 2024-07-09 Wake Forest University Health Sciences Composition with polymer and ceramic and methods of use thereof
CN106491246B (zh) * 2016-11-30 2018-02-27 重庆博仕康科技有限公司 用于经蝶垂体腺瘤手术的颅底修补装置
CN106510896A (zh) * 2016-12-06 2017-03-22 王晓松 人工硬脑膜
EP3441030B1 (en) 2017-08-11 2020-05-13 Stryker European Holdings I, LLC Deformable cranial burr hole plate and deformation instrument therefor
EP4606395A3 (en) 2019-02-09 2025-11-19 Theracell, LLC Demineralized bone fiber implant compositions and their methods of fabrication
EP3818994A1 (en) * 2019-11-08 2021-05-12 Septodont ou Septodont SAS ou Specialites Septodont Non-breaking filament for shaping bone and dental substitutes
WO2021097438A1 (en) 2019-11-15 2021-05-20 4Web, Inc. Piezoelectric coated implants and methods of using piezoelectric coated implants to repair bone structures
EP4076288B1 (en) 2019-12-20 2024-10-30 Tepha, Inc. Resorbable implants for reconstruction of bone defects
US12201746B2 (en) 2020-02-06 2025-01-21 Board Of Trustees Of The University Of Arkansas Expandable bone and tissue regeneration system, and applications of same
CA3167072A1 (en) * 2020-02-06 2021-08-12 Alexandru S. Biris Expandable bone and tissue regeneration system, and applications of same
WO2022011173A1 (en) 2020-07-08 2022-01-13 4Web, Inc. Implants having bone growth promoting agents contained within biodegradable materials
KR102354646B1 (ko) * 2020-08-03 2022-01-25 주식회사 티앤알바이오팹 개두술용 비고정형 임플란트 및 이의 제조 방법
EP4192393A4 (en) * 2020-08-10 2024-11-13 Advanced Development of Additive Manufacturing, Inc. METHOD FOR MANUFACTURING AN INDIVIDUAL 3D PRINTED CERAMIC BIORESORBABLE BONE IMPLANT FOR USE IN TRAUMATOLOGY AND ORTHOPEDICS
US20240390668A1 (en) * 2021-09-01 2024-11-28 Cochlear Limited Cured ring seal
US11771470B1 (en) 2022-12-07 2023-10-03 Orlando Health, Inc. Affixation device for securing bone flap

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364400A (en) * 1992-02-14 1994-11-15 American Cyanamid Co. Interference implant
US5383932A (en) * 1993-04-27 1995-01-24 Johnson & Johnson Professional, Inc. Absorbable medullary plug

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5306311A (en) * 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
JPH063611Y2 (ja) * 1987-09-24 1994-02-02 京セラ株式会社 脳外科用バーホールキャップ
JPH0373435A (ja) 1989-05-13 1991-03-28 Sekisui Chem Co Ltd 酸化ケイ素被覆光情報記録媒体およびその製造方法
JPH03126113U (enExample) 1990-03-30 1991-12-19
JPH07108303B2 (ja) * 1991-01-10 1995-11-22 晋輔 高杉 頭蓋骨弁固定用バーホールボタン
JPH063611A (ja) 1991-06-26 1994-01-14 Asahi Optical Co Ltd 走査式光学装置
JPH0584306A (ja) 1991-09-26 1993-04-06 Sumitomo Bakelite Co Ltd 医療用誘導チユーブ
WO1993015694A1 (en) * 1992-02-14 1993-08-19 Board Of Regents, The University Of Texas System Multi-phase bioerodible implant/carrier and method of manufacturing and using same
US5503164A (en) * 1994-01-28 1996-04-02 Osteogenics, Inc. Device and method for repair of craniomaxillofacial bone defects including burr holes
US20020032488A1 (en) * 1994-05-13 2002-03-14 Brekke John H. Device for regeneration of articular cartilage and other tissue
JP3243685B2 (ja) * 1995-12-27 2002-01-07 タキロン株式会社 インプラント材料及びその製造方法
JP3228678B2 (ja) * 1996-04-26 2001-11-12 京セラ株式会社 脳外科用バーホールキャップ
US5899939A (en) * 1998-01-21 1999-05-04 Osteotech, Inc. Bone-derived implant for load-supporting applications
US6350284B1 (en) 1998-09-14 2002-02-26 Bionx Implants, Oy Bioabsorbable, layered composite material for guided bone tissue regeneration
US7662409B2 (en) * 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
ES2230170T3 (es) * 1999-12-15 2005-05-01 Zimmer Gmbh Preparacion para la reparacion de articulaciones en el hombre o el animal, como consecuencia de anomalias cartilaginosas o cartilagino-oseas.
WO2001060288A1 (en) * 2000-02-18 2001-08-23 Isotis N.V. Plug for insertion into a bone canal
US20020183858A1 (en) * 2001-06-05 2002-12-05 Contiliano Joseph H. Attachment of absorbable tissue scaffolds to scaffold fixation devices
GB0208418D0 (en) * 2002-04-11 2002-05-22 Univ Aston Polymeric fibre
US8187326B2 (en) * 2002-05-22 2012-05-29 Advanced Technologies And Regenerative Medicine, Llc. Attachment of absorbable tissue scaffolds to fixation devices
EP1691726B1 (en) 2003-11-21 2013-01-16 Osteopore International Pte Ltd Bioabsorbable plug implants
JP3126113U (ja) 2006-08-02 2006-10-12 有限会社ムラリー 伸縮紐

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364400A (en) * 1992-02-14 1994-11-15 American Cyanamid Co. Interference implant
US5383932A (en) * 1993-04-27 1995-01-24 Johnson & Johnson Professional, Inc. Absorbable medullary plug

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JP特开平9-173435A 1997.07.08

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI720668B (zh) * 2019-10-29 2021-03-01 可成生物科技股份有限公司 頭顱骨植入物

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US20140358238A1 (en) 2014-12-04
AU2004291022A1 (en) 2005-06-02
EP1691726B1 (en) 2013-01-16
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US9492279B2 (en) 2016-11-15
WO2005048885A1 (en) 2005-06-02
AU2004291022C1 (en) 2009-11-12
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