CN1966660A - Device and method for large scale culturing Haemotococcum pluvies and converting astaxanthin - Google Patents
Device and method for large scale culturing Haemotococcum pluvies and converting astaxanthin Download PDFInfo
- Publication number
- CN1966660A CN1966660A CNA2006101546780A CN200610154678A CN1966660A CN 1966660 A CN1966660 A CN 1966660A CN A2006101546780 A CNA2006101546780 A CN A2006101546780A CN 200610154678 A CN200610154678 A CN 200610154678A CN 1966660 A CN1966660 A CN 1966660A
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- China
- Prior art keywords
- astaxanthin
- large scale
- reactor
- haematocoocus pluvialls
- flexible pipe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 title claims abstract description 49
- 235000013793 astaxanthin Nutrition 0.000 title claims abstract description 49
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 title claims abstract description 49
- 229940022405 astaxanthin Drugs 0.000 title claims abstract description 49
- 239000001168 astaxanthin Substances 0.000 title claims abstract description 49
- 238000012258 culturing Methods 0.000 title claims abstract description 25
- 238000000034 method Methods 0.000 title claims abstract description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 75
- 238000006243 chemical reaction Methods 0.000 claims abstract description 15
- 238000005286 illumination Methods 0.000 claims abstract description 14
- 241000168517 Haematococcus lacustris Species 0.000 claims abstract description 12
- 238000003306 harvesting Methods 0.000 claims abstract description 8
- 238000011081 inoculation Methods 0.000 claims abstract description 6
- 235000015097 nutrients Nutrition 0.000 claims description 40
- 230000007246 mechanism Effects 0.000 claims description 21
- 238000001802 infusion Methods 0.000 claims description 16
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 10
- 239000007789 gas Substances 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 10
- 230000002378 acidificating effect Effects 0.000 claims description 8
- 230000001105 regulatory effect Effects 0.000 claims description 6
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 230000008676 import Effects 0.000 claims description 5
- 229910052757 nitrogen Inorganic materials 0.000 claims description 5
- 229910052698 phosphorus Inorganic materials 0.000 claims description 5
- 239000011574 phosphorus Substances 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 239000008239 natural water Substances 0.000 abstract description 4
- 239000002028 Biomass Substances 0.000 abstract description 2
- 235000016709 nutrition Nutrition 0.000 abstract description 2
- 230000035764 nutrition Effects 0.000 abstract description 2
- 238000005273 aeration Methods 0.000 abstract 2
- 239000012531 culture fluid Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 description 8
- 238000009825 accumulation Methods 0.000 description 4
- 241000195493 Cryptophyta Species 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 241000277269 Oncorhynchus masou Species 0.000 description 2
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- 230000000050 nutritive effect Effects 0.000 description 2
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- 230000008569 process Effects 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 2
- 229940033663 thimerosal Drugs 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 1
- 241000168525 Haematococcus Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000009360 aquaculture Methods 0.000 description 1
- 244000144974 aquaculture Species 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 235000011089 carbon dioxide Nutrition 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
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- 235000013305 food Nutrition 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 150000004965 peroxy acids Chemical class 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
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- 238000012360 testing method Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000001228 trophic effect Effects 0.000 description 1
- 238000013022 venting Methods 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/02—Photobioreactors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/06—Tubular
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/56—Floating elements
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2006101546780A CN100453635C (en) | 2006-11-20 | 2006-11-20 | Device and method for large scale culturing Haemotococcum pluvies and converting astaxanthin |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2006101546780A CN100453635C (en) | 2006-11-20 | 2006-11-20 | Device and method for large scale culturing Haemotococcum pluvies and converting astaxanthin |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1966660A true CN1966660A (en) | 2007-05-23 |
CN100453635C CN100453635C (en) | 2009-01-21 |
Family
ID=38075644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2006101546780A Active CN100453635C (en) | 2006-11-20 | 2006-11-20 | Device and method for large scale culturing Haemotococcum pluvies and converting astaxanthin |
Country Status (1)
Country | Link |
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CN (1) | CN100453635C (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009149578A1 (en) | 2008-06-09 | 2009-12-17 | Victor Cifuentes Guzman | Use of gene in the synthesis of astaxanthin |
CN101245310B (en) * | 2008-03-17 | 2011-07-20 | 大连汇新钛设备开发有限公司 | Series connected type unit cell algae optical biological reaction device |
CN102604836A (en) * | 2012-03-01 | 2012-07-25 | 武汉凯迪工程技术研究总院有限公司 | Production method and device for preventing chytrid pollution in haematococcus pluvialis |
CN102827766A (en) * | 2012-08-17 | 2012-12-19 | 宁波红龙生物科技有限公司 | Photobioreactor for large-scale production of astaxanthin by haematococcus pluvialis |
CN103396951A (en) * | 2013-08-12 | 2013-11-20 | 云南爱尔康生物技术有限公司 | Method for cultivating haematococcus pluvialis in large scale and producing natural astaxanthin seasoning packet by haematococcus pluvialis |
CN106906138A (en) * | 2017-05-05 | 2017-06-30 | 宁波浮田生物技术有限公司 | A kind of haematococcus pluvialis high concentration induces the device and method of astaxanthin accumulation |
CN107641594A (en) * | 2017-11-27 | 2018-01-30 | 常德炎帝生物科技有限公司 | A kind of differential open pipe bioreactor for microdisk electrode |
CN112280652A (en) * | 2020-10-27 | 2021-01-29 | 南京师范大学镇江创新发展研究院 | Flowing type microalgae photobioreactor based on light energy gradient utilization |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1226407C (en) * | 2002-07-18 | 2005-11-09 | 中山大学 | Method for improving haematococcus pluvialis multiplication to produce pure strain in photo-biological reactor |
CN2763279Y (en) * | 2005-01-26 | 2006-03-08 | 湖北师范学院 | Gas-lifting type photo-bioreactor for rain-growth red spherical chlorella high density culture |
-
2006
- 2006-11-20 CN CNB2006101546780A patent/CN100453635C/en active Active
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101245310B (en) * | 2008-03-17 | 2011-07-20 | 大连汇新钛设备开发有限公司 | Series connected type unit cell algae optical biological reaction device |
WO2009149578A1 (en) | 2008-06-09 | 2009-12-17 | Victor Cifuentes Guzman | Use of gene in the synthesis of astaxanthin |
CN102604836A (en) * | 2012-03-01 | 2012-07-25 | 武汉凯迪工程技术研究总院有限公司 | Production method and device for preventing chytrid pollution in haematococcus pluvialis |
WO2013127280A1 (en) * | 2012-03-01 | 2013-09-06 | 中盈长江国际新能源投资有限公司 | Production method and device for preventing and treating contamination of paraphysoderma sedebokerensis in haematococcus pluvialis |
CN102827766A (en) * | 2012-08-17 | 2012-12-19 | 宁波红龙生物科技有限公司 | Photobioreactor for large-scale production of astaxanthin by haematococcus pluvialis |
CN103396951A (en) * | 2013-08-12 | 2013-11-20 | 云南爱尔康生物技术有限公司 | Method for cultivating haematococcus pluvialis in large scale and producing natural astaxanthin seasoning packet by haematococcus pluvialis |
CN106906138A (en) * | 2017-05-05 | 2017-06-30 | 宁波浮田生物技术有限公司 | A kind of haematococcus pluvialis high concentration induces the device and method of astaxanthin accumulation |
CN106906138B (en) * | 2017-05-05 | 2023-08-29 | 宁波浮田生物技术有限公司 | Device and method for inducing astaxanthin accumulation in haematococcus pluvialis at high concentration |
CN107641594A (en) * | 2017-11-27 | 2018-01-30 | 常德炎帝生物科技有限公司 | A kind of differential open pipe bioreactor for microdisk electrode |
CN107641594B (en) * | 2017-11-27 | 2020-12-29 | 常德炎帝生物科技有限公司 | Differential pressure type open pipeline bioreactor for microalgae culture |
CN112280652A (en) * | 2020-10-27 | 2021-01-29 | 南京师范大学镇江创新发展研究院 | Flowing type microalgae photobioreactor based on light energy gradient utilization |
Also Published As
Publication number | Publication date |
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CN100453635C (en) | 2009-01-21 |
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C14 | Grant of patent or utility model | ||
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Owner name: LIJIANG CHENGHAI BER BIOLOGICAL DEVELOPMENT CO., L Free format text: FORMER OWNER: NINGBO UNIVERSITY Effective date: 20100818 |
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Free format text: CORRECT: ADDRESS; FROM: 315211 NO.818, FENGHUA ROAD, JIANGBEI DISTRICT, NINGBO CITY, ZHEJIANG PROVINCE TO: 674200 GUANJIA VILLAGE, DONGHU VILLAGE COMMITTEE, CHENGHAI TOWN, YONGSHENG COUNTY, LIJIANG CITY, YUNNAN PROVINCE |
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Effective date of registration: 20100818 Address after: 674200 Lijiang City, Yunnan province Yongsheng County Cheng Hai Zhen East Lake Cun Wei Hui Guan Jia Cun Patentee after: Lijiang Chenghai Bao'er Biological Development Co., Ltd. Address before: 315211 Zhejiang Province, Ningbo Jiangbei District Fenghua Road No. 818 Patentee before: Ningbo University |
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TR01 | Transfer of patent right |
Effective date of registration: 20171024 Address after: 674200 Lijiang City, Yunnan province Yongsheng County Cheng Hai Zhen East Lake Cun Wei Hui Guan Village No. 18 Patentee after: Tan Yinghong Address before: 674200 Lijiang City, Yunnan province Yongsheng County Cheng Hai Zhen East Lake Cun Wei Hui Guan Jia Cun Patentee before: Lijiang Chenghai Bao'er Biological Development Co., Ltd. |
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Effective date of registration: 20201112 Address after: 674202 Lijiang City, Yunnan province Yongsheng County Cheng Hai Zhen East Lake Cun Wei Hui Guan Jia Cun Patentee after: LIJIANG CHENGHAI BAO'ER BIOLOGICAL DEVELOPMENT Co.,Ltd. Address before: 674200 Lijiang City, Yunnan province Yongsheng County Cheng Hai Zhen East Lake Cun Wei Hui Guan Village No. 18 Patentee before: Tan Yinghong |
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TR01 | Transfer of patent right |