CN1927292A - External use drug for treating burn, bedsore, chronic ulcer and etc. and preparation method thereof - Google Patents

Abstract

The invention discloses an externally-used medicament for the treatment of burns, bedsore and chronic ulcer, as well as the process for preparation, the medicament is prepared from the following medicinal herbs: Chinese angelica root 30-80 parts, coptis root 30-180 parts, garden burnet root 30-120 parts, giant knotweed rhizome 30-90 parts, rheum officinale 30-90 parts, borneol 30-90 parts, emollient 30-90 parts and water 3000-5000 parts.

Description

A kind of external used medicine for the treatment of burn, decubital ulcer, chronic ulcer etc. and preparation method thereof

Technical field

The present invention relates to a kind of medicine, particularly a kind of external used medicine for the treatment of burn, decubital ulcer, chronic ulcer etc. and preparation method thereof.

Background technology

Treatment at present causes skin injury easily as burn, decubital ulcer, chronic ulcer etc. after treatment, mainly be by cutting crust skin-grafting (from body skin-grafting and allo-skin graft), using epidermal growth factor.But this kind method cost height, easy infection can not satisfy from the body skin large defect, to allograft skin at present also among exploring.According to relevant: it is to seek the skin source on one's body from piglets to be implanted on one's body the human body that an ancestor Shen group subsidizes southwestern hospital development allograft skin.Cultivate skin with hair abroad.General headquarters are located at the Biocare biotechnology treatment company in Leipzig and the new therapy of Switzerland scientist joint research and development is: pull up 50 to 100 hairs at the laboratory cultures human body skin with tweezers from patient's head.Become the skin of transplantation from the specific culture thing, approximately needed for 4 week to wound.This kind method cost is higher, and the patient can not get timely medical treatment.The epidermal growth factor curative effect is very dissatisfied.

Summary of the invention

Purpose of the present invention is exactly at existing defective and the deficiency that causes the external used medicine of skin injury to exist owing to burn, decubital ulcer, chronic ulcer etc. for the treatment of, and a kind of external used medicine for the treatment of burn, decubital ulcer, chronic ulcer etc. and preparation method thereof is provided.

For achieving the above object, the present invention adopts following technical scheme:

A kind of external used medicine for the treatment of burn, decubital ulcer, chronic ulcer etc., make by following medicaments in part by weight:

30～80 parts of Radix Angelicae Sinensis

30～180 parts of Rhizoma Coptidis

30～120 parts of Radix Sanguisorbaes

30～90 parts of Rhizoma Polygoni Cuspidati

30～90 parts of Radix Et Rhizoma Rhei

30～90 parts of Borneolum Syntheticums

30～90 parts of emollient

3000～5000 parts in water.

Described emollient is one or both in Oleum sesami, the siritch.

In medicine used in the present invention:

Radix Angelicae Sinensis has the effect of enriching blood and invigorating blood circulation, and various bacteria is had antibacterial action.

Rhizoma Coptidis has pathogenic fire purging, dampness, antidotal effect, and contained effective ingredient all has stronger bacteriostasis to Hemolytic streptococcus, meningococcus, Diplococcus pneumoniae, vibrio cholera, anthrax bacillus and staphylococcus aureus, dysentery bacterium, escherichia coli.

Radix Sanguisorbae has cooling blood for hemostasis, the effect of heat-clearing and toxic substances removing.Its contained effective ingredient can stop blooding, and staphylococcus aureus, escherichia coli, bacillus pyocyaneus are had inhibitory action.

Rhizoma Polygoni Cuspidati have dispel the wind, dampness removing, removing blood stasis with potent drugs, the effect of stimulating the menstrual flow.Staphylococcus aureus, micrococcus catarrhalis, group B streptococcus, escherichia coli, bacillus pyocyaneus there is inhibitory action.

Radix Et Rhizoma Rhei has that the poison that purges heat, removing mass stagnate, the effect of clots absorbing blood.Staphylococcus aureus, dysentery bacterium, streptococcus there is inhibitory action.

Borneolum Syntheticum has the effect of detumescence, pain relieving, logical all keys, the stagnated fire of loosing.Can stimulate partial Cold receptor, slight local anesthesia effect is arranged, can pain relieving and anticorrosion.Borneolum Syntheticum is controlled the apoplexy locked mouth, calentura coma ， Jing Epilepsy expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, conjunctivitis, enterobiasis.1. the refreshment of having one's ideas straightened out: be used for apoplexy, expectorant heat, the coma key closes, and makes accessory drugs more.2. clearing away heat to alleviate pain: kindly control conjunctival congestion and swelling pain, laryngopharynx swelling and pain, pathopyretic ulcer and the sore being festered and unhealed do not close up for a long time.3. treatment oral ulcer, suppurative otitis media, colpitis mycotica, the acute-chronic purulent otitis media, surgical infection, apoplexy, convulsions, sore throat toothache, dispute are festered, the scabies skin ulcer is itched, traumatic injury, swelling and pain due to blood stasis etc.Be used for surgery, help affected part granulation promoting, pain relieving, concentration.

Oleum sesami: moistening dryness for relaxing bowels, removing toxic substances and promoting granulation.Can also play the effect of profit skin, not allow newborn chapped skin and injured.

Siritch: in contain unsaturated fatty acid to the human body beneficial, and the ratio of forming is suitable, is not easy oxidation.Especially be rich in and enhance metabolism, improve the blood capillary circulation, bring the vitamin e of skin cell nutrition.Vitamin e can be divided into the α type, β type, γ type, δ type etc., and siritch is to belong to the γ type.γ type vitamin e is that excellent polyphenoils mass-energy prevents to wear out effectively.The more important thing is that the oleic acid composition that contains in the siritch is also confirmed that diseases such as the gastric ulcer of inhibition, asthma are arranged, prevents that skin matter from worsening, and improves the effect of immunity by medical science.With regard to the skin protection maintenance, the contained composition of siritch all has the inhibitory action that prevents trouble before it happens for problems such as wrinkle, black speck, scaly dry skins.Therefore, except edible, do the anti-skin product of self-control beauty treatment, also can prevent skin aging with siritch.

Prepare the method for external used medicines such as above-mentioned treatment burn, decubital ulcer, chronic ulcer, may further comprise the steps:

A), by weight take by weighing Radix Angelicae Sinensis, Rhizoma Coptidis, Radix Sanguisorbae, Rhizoma Polygoni Cuspidati, Radix Et Rhizoma Rhei, Borneolum Syntheticum, water, emollient, Radix Angelicae Sinensis, Rhizoma Coptidis, Radix Sanguisorbae, Rhizoma Polygoni Cuspidati, Radix Et Rhizoma Rhei are put into container, add entry, heat boiledly, decoct 20～40 minutes;

B), the elimination medicinal residues, taking liquid decocts under boiled state, concentrate 20～40 minutes;

C), add emollient, Borneolum Syntheticum, stir and make the Borneolum Syntheticum dissolving down, and mix homogeneously, be cooled to room temperature, bottle.

Medicine of the present invention is a situation about can not grow according to behind the human body skin damnification, in conjunction with the Chinese medicine characteristic, adopts scientific method, a kind of biological preparation that extracts active ingredient and make, at the damaged place of human body skin, make damaged skin growth with medicine wrapping of the present invention, obtain satisfactory effect.

A kind of treatment of the present invention causes the external used medicine of skin injury because of burn, decubital ulcer, chronic ulcer etc., used medicine is cheap and easy to get, compatibility of drugs science, reasonable, through extracting the active ingredient of medicine, a kind of biological preparation of making, can treat burn, decubital ulcer, chronic ulcer etc. and cause skin injury, need not make skin graft, can alleviate the high cost that the patient brings because of skin-grafting.Preparation method of the present invention is simple, and medication is convenient.

The specific embodiment

Below in conjunction with embodiment the present invention is described in further detail.

Embodiment 1:

Take by weighing: Radix Angelicae Sinensis 30 grams, Rhizoma Coptidis 30 grams, Radix Sanguisorbae 30 grams, Rhizoma Polygoni Cuspidati 30 grams, Radix Et Rhizoma Rhei 30 grams, Borneolum Syntheticum 30 grams, Oleum sesami 30 grams, water 3000 grams.

A), Radix Angelicae Sinensis, Rhizoma Coptidis, Radix Sanguisorbae, Rhizoma Polygoni Cuspidati, Radix Et Rhizoma Rhei are put into container, add entry, heat boiledly, decoct 20～40 minutes;

B), the elimination medicinal residues, taking liquid decocts under boiled state, concentrate 20～40 minutes;

C), add emollient, Borneolum Syntheticum, stir and make the Borneolum Syntheticum dissolving down, and mix homogeneously, be cooled to room temperature, become paste, bottle.

Embodiment 2:

Take by weighing: Radix Angelicae Sinensis 80 grams, Rhizoma Coptidis 180 grams, Radix Sanguisorbae 90 grams, Rhizoma Polygoni Cuspidati 120 grams, Radix Et Rhizoma Rhei 90 grams, Borneolum Syntheticum 90 grams, Oleum sesami 90 grams, water 5000 grams.

Preparation method is with embodiment 1.

Embodiment 3:

Take by weighing: Radix Angelicae Sinensis 50 grams, Rhizoma Coptidis 100 grams, Radix Sanguisorbae 60 grams, Rhizoma Polygoni Cuspidati 80 grams, Radix Et Rhizoma Rhei 80 grams, Borneolum Syntheticum 80 grams, siritch 80 grams, water 4000 grams.

Preparation method is with embodiment 1.

Therapeutic effect of the present invention can be confirmed by following clinical example:

1, Zhang, the man, 41 years old, from the beginning gone up pouring on July 21st, 2003 by boiled water and scald women's head-ornaments portion, cervical region, chest, abdominal part, left upper extremity shoulder, right upper extremity shoulder etc., part skin exfoliation in the back down, as seen a plurality of blisters of differing in size of wound surface, the gross area about 26%, wherein dark 2 spends about 10%, shallow 2 degree 12%, hinder and all cured after 16 days through giving the skin growth extract for treating to my institute in back 1 hour, do not stay cicatrix.

2, Wang so-and-so, the man, 36 years old, because of right hand forearm and cervical region are burnt by gunpowder, skin eschar blackout on hand, cervical region has a plurality of blisters that differ in size, and the gross area is about 8%, hinders to give debridement to my institute in back 30 minutes, use the skin growth extract for treating, after 11 days, cure fully, do not stay cicatrix.

3, Dong so-and-so, the woman, 78 years old, crouch for a long time and cause skin of back and fester because of suffering from cerebral thrombosis, senile dementia, about 5 * 7.5 square centimeters of area, through intravenous nutrition support and anti-inflammatory treatment, external skin auxin treatment recovery from illness after 38 days.

4, model so-and-so, man, 67 years old, careless at work left instep is by the copper water scald before 26 years, and treat the 5th the People's Hospital in the Chongqing City at once, and nothing is clearly better, through twice skin-grafting, wound surface is not still cured, and is chronic ulcer, does not still have improvement behind a small bay in a river burn hospital of Lee family dressing change, after this, secretions appears in a patient left side sufficient wound surface repeatedly, and is heavy when light during symptom, day cures surplus in the of 90 after giving the skin growth extract for treating.

5, Hu, man, 56 years old, because of being pressed on the pressure cooker, the epilepsy both hands faint, when being found by the household, both hands palms skin has been scalded white, to refer to that abdomen is for very, part is 3 degree burns, give the skin growth hormone bandaging method for treating, antiinflammatory, fluid infusion and Supporting Therapy cured after 48 days fully simultaneously, the left hand palm stays a little cicatrix, about 0.5 * 0.3cm size.

6, Zhang, the man, 48 years old, ignite gas tank accidentally because of the welded bridge reinforcing bar and injure cervical region, chest, abdominal part and two upper limb, cause cervical region, chest, skin of abdomen and come off, about 11 * the 21cm of area, two skin of upper extremity come off, the about 6 * 8cm of area, give skin growth hormone and antiinflammatory Supporting Therapy after, cured, and do not stay cicatrix in 13 days.

Claims (3)

1, a kind of external used medicine for the treatment of burn, decubital ulcer, chronic ulcer etc. and preparation method thereof is characterized in that: made by following medicaments in part by weight:

30～80 parts of Radix Angelicae Sinensis

30～180 parts of Rhizoma Coptidis

30～120 parts of Radix Sanguisorbaes

30～90 parts of Rhizoma Polygoni Cuspidati

30～90 parts of Radix Et Rhizoma Rhei

30～90 parts of Borneolum Syntheticums

30～90 parts of emollient

3000～5000 parts in water.

2, a kind of external used medicine for the treatment of burn, decubital ulcer, chronic ulcer etc. according to claim 1 and preparation method thereof, it is characterized in that: described emollient is one or both in Oleum sesami, the siritch.

3, the method for external used medicines such as burn, decubital ulcer, chronic ulcer is treated in a kind of preparation according to claim 1, it is characterized in that may further comprise the steps:

A), by weight take by weighing Radix Angelicae Sinensis, Rhizoma Coptidis, Radix Sanguisorbae, Rhizoma Polygoni Cuspidati, Radix Et Rhizoma Rhei, Borneolum Syntheticum, water, emollient, Radix Angelicae Sinensis, Rhizoma Coptidis, Radix Sanguisorbae, Rhizoma Polygoni Cuspidati, Radix Et Rhizoma Rhei are put into container, add entry, heat boiledly, decoct 20～40 minutes;

B), the elimination medicinal residues, taking liquid decocts under boiled state, concentrate 20～40 minutes;

C), add emollient, Borneolum Syntheticum, stir and make the Borneolum Syntheticum dissolving down, and mix homogeneously, be cooled to room temperature, bottle.