CN104958613A - Chinese medicinal composition for treating accumulated toxin rotten bedsore and preparation method thereof - Google Patents
Chinese medicinal composition for treating accumulated toxin rotten bedsore and preparation method thereof Download PDFInfo
- Publication number
- CN104958613A CN104958613A CN201510446338.4A CN201510446338A CN104958613A CN 104958613 A CN104958613 A CN 104958613A CN 201510446338 A CN201510446338 A CN 201510446338A CN 104958613 A CN104958613 A CN 104958613A
- Authority
- CN
- China
- Prior art keywords
- herba
- parts
- chinese medicine
- chinese
- alkalium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the field of Chinese medicaments, and in particular relates to a Chinese medicinal composition for treating accumulated toxin rotten bedsore and a preparation method thereof. The Chinese medicinal composition follows the medication principle of a traditional Chinese medical formula, and is prepared from eight Chinese medicinal herbs including ajuga pantantha, teucrium viscidum, Japanese claw fern herb, xanthium sibiricum, cynanchum atratum, polygonum cuspidatum, crystal soda and husked sorghum; the whole formula has the effects of clearing heat, detoxifying, promoting blood circulation to dissipate blood stasis, promoting pustulation of sore to expel pus, clearing damp to engender flesh and relieving swelling and pain, has good treatment effect on accumulated toxin rotten bedsore, quick response and short treatment course, and relieves the pain of patients and the labor intensity of nurses; and the Chinese medicinal composition can be easily accepted by patients, and is suitable for treating bedsore in hospitals and at home. Clinical application verifies that the effective rate for the accumulated toxin rotten bedsore can reach over 90%.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind for the treatment of and accumulate Chinese medicine composition of malicious decomposed type decubital ulcer and preparation method thereof.
Background technology
Decubital ulcer is also known as pressure ulcer; a kind of not rise because of long-term bed; a kind of skin infection class disease of the limitation shallow table skin injury that body weight causes with friction; prolonged not more for main feature with the open sore part; it is multiple that to be born in Musclar layer thinner; lack the bone knuckle place of fat protection and frequent pressurized, as places such as omoplate, ancon, sacrococcygeal region, heels.The treatment of decubital ulcer is generally anti-inflammation is main, use antibiotic, be coated with the medicine for external application such as iodine tincture, metronidazole outside employing local and treat, but use these medicines to have stronger zest to wound surface, and, along with the increase of drug resistance strain, many antibacterials are insensitive to antibiotic, affect clinical efficacy, toxic and side effects is large, the healing cycle is long, and be difficult to radical cure, therapeutic effect is undesirable.
The traditional Chinese medical science is thought, decubital ulcer is due to excessive rest on bed impairing QI, the deficiency of vital energy and hematogenous blockage; Outward because somatotopic is oppressed for a long time continuously and rubs, cause blood stasis due to qi deficiency, local failure of skin and muscle to be nourished, skin and flesh necrosis forms.Occur dark red, gradually dark violet from the beginning of pressurized position, become rapidly black dead skin, pain or not bitterly, dead skin and surrounding form obvious boundary, around swollen gesture puts down undiscipline of collapsing.Continue, dead skin and normal skin boundary liquefy gradually and fester, and pus is smelly dirty, rot to expand below the circumferential dead skin of wound surface four, after dead skin comes off, form larger ulcer surface, can deeply and fascia, muscle layer, periosteum.
If wound surface rots to organize and comes off gradually, occur cerise granulation, create the very fast person of all skin growths, decubital ulcer is expected healing.Spread more than if rot, ulcer surface day by day expands, and around swollen gesture continues development, it is thin that ulcer surface has celadon pus to smell as of rotten fish, or as powder slurry sewage, and the thin person of the weak shape of the companion body, then decubital ulcer delay is difficult more, even occurs that septicopyemia is walked to alter, heavily the demonstrate,proving of interior biography internal organs, and prognosis is poor.Therefore be divided into by its clinical characters and systemic conditions: qi stagnation and blood stasis type, accumulate poison rot type, QIXUELIANGXU type.
Traditional Chinese medical herbal treatment decubital ulcer has unique treatment advantage, and in recent years, the medicine of numerous treatment decubital ulcer is in the news out, and so these medicine ubiquity flavour of a drug are various, and formula is complicated, and raw medicinal material not easily obtains, preparation difficulty shortcoming.
Summary of the invention
The object of the present invention is to provide a kind of good effect, instant effect, Chinese medicine composition that malicious decomposed type decubital ulcer is accumulate in easy to use, that treatment cost is low treatment.This Chinese medicine composition is that inventor utilizes Traditional Chinese medical theory, is particular about Overall View, improves the immunity of animal economy, prevent traumatic infection, expansion, intensification, removing the necrotic tissue and promoting granulation, blood circulation promoting while determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, evident in efficacy.
For reaching above object, the technical solution adopted in the present invention is: the Chinese medicine composition of malicious decomposed type decubital ulcer is accumulate in this treatment, by eight taste Chinese herbal medicine elaborates such as Herba boeae clarkeanae, Herba Chenopodii Hybridi, Herba Onychii japonici, Herba Xanthii, Radix Cynanchi Atrati, Rhizoma Polygoni Cuspidati, alkalium, Sorghum vulgare Pers.s.
For improving the present invention to the curative effect of accumulateing malicious decomposed type decubital ulcer, through groping in a large number to sum up, inventor thinks that this Chinese medicine composition to be made up of the Chinese herbal medicine of following weight portion and all to be had good curative effect: Herba boeae clarkeanae 21-27 part, Herba Chenopodii Hybridi 13-18 part, Herba Onychii japonici 15-20 part, Herba Xanthii 6-9 part, Radix Cynanchi Atrati 7-12 part, Rhizoma Polygoni Cuspidati 9-14 part, alkalium 4-7 part, Sorghum vulgare Pers. 7-11 part.
One of preferred version optimized is: the Chinese medicine composition of malicious decomposed type decubital ulcer is accumulate in this treatment, it is characterized in that it is made up of the Chinese herbal medicine of following weight portion: Herba boeae clarkeanae 24 parts, Herba Chenopodii Hybridi 15 parts, Herba Onychii japonici 17 parts, Herba Xanthii 7 parts, Radix Cynanchi Atrati 8 parts, Rhizoma Polygoni Cuspidati 10 parts, alkalium 5 parts, Sorghum vulgare Pers. 9 parts.
Another preferred version optimized is: the Chinese medicine composition of malicious decomposed type decubital ulcer is accumulate in this treatment, it is characterized in that it is made up of the Chinese herbal medicine of following weight portion: Herba boeae clarkeanae 25 parts, Herba Chenopodii Hybridi 17 parts, Herba Onychii japonici 20 parts, Herba Xanthii 8 parts, Radix Cynanchi Atrati 10 parts, Rhizoma Polygoni Cuspidati 12 parts, alkalium 5 parts, Sorghum vulgare Pers. 10 parts.
Fang Xiewei of the present invention: Herba boeae clarkeanae bitter cold, kind heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling; Herba Chenopodii Hybridi blood circulation promoting and blood stasis dispelling, not removing blood stasis of invigorating blood circulation; Two medicine mutual reinforcement between compatibilities, both clearing away heat,cooling blood and removing toxins, blood circulation promoting and blood stasis dispelling detumescence is monarch drug again.Herba Onychii japonici is apt to heat-clearing and toxic substances removing, inducing diuresis and reducing edema, has effect of removing the necrotic tissue and promoting granulation concurrently; Radix Cynanchi Atrati clearing away heat and cooling blood, skin ulcer is controlled in removing toxic substances, and can hold back conjunction skin ulcer mouth; Rhizoma Polygoni Cuspidati expelling wind and removing dampness, dissipating blood stasis analgesic therapy, both principal drug assistance heat-clearing and toxic substances removing, promoting tissue regeneration by removing blood stasis, again can be inducing diuresis and reducing edema, dissipating blood stasis analgesic therapy, and dispelling wind for relieving itching, holds back the conjunction open sore part, is ministerial drug.Alkalium softening hardness and disperse swelling, dissipating blood stasis evacuation of pus; Sorghum vulgare Pers. expelling wind and removing dampness, removing toxic substances sore, helps the evacuation of pus of monarch-minister drug dissipating blood stasis, and removing toxic substances sore is adjuvant drug.Herba Xanthii property is pungent kind disperses, bitter dampness is turbid, warm in nature sensible, antipruritic pain relieving, priming permeates, and is adjuvant.Full side works in coordination with mutually, interacts, combined into it, has heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, antalgesic-antipruritic, healing up sore and subduing swelling, the effect of putrefaction-removing granulation-promoting.
Pharmacologically active being described below in the data such as " Chinese Pharmacopoeia ", " Chinese draft " of the present invention's each medicinal raw material used.
Herba boeae clarkeanae: [source] Labiatae bugle Herba boeae clarkeanae Ajuga nipponensis Makino, with all herbal medicine.[nature and flavor] are bitter, cold.[function cures mainly] antiinflammatory, removing heat from blood, synthetism.For bronchitis, tonsillitis, lung-heat hemoptysis, skin ulcer, furuncle, mastitis, proctoptosis, hemorrhoid, tumor, traumatic hemorrhage, burn and scald, fracture.
Herba Chenopodii Hybridi: [source] is the herb of chenopod great Ye Herba chenopodii.[nature and flavor] are sweet, flat.[function cures mainly] stops blooding, and invigorates blood circulation.Control menoxenia, metrorrhagia, spitting of blood, epistaxis, hematuria, sore and toxic.
Herba Onychii japonici: [nature and flavor] are bitter, cold.[function cures mainly] heat clearing away, dampness removing, removing toxic substances, hemostasis.Control anemopyretic cold, acute gastroenteritis, dysentery, jaundice, hemoptysis, spit blood, have blood in stool, hematuria, furuncle, wound swells and ache." the practical Chinese herbal medicine in Guangxi newly selects ": " detoxicating, relieving inflammation, removing the necrotic tissue and promoting granulation.
Herba Xanthii: [nature and flavor] bitter in the mouth; Pungent; Cold nature; Mild toxicity.[return through] returns lung; Spleen; Liver Channel.[function cures mainly] dispels the wind; Heat radiation; Dehumidifying; Removing toxic substances.Main flu; Wind syndrome of head; Dizzy; Nasal sinusitis, conjunctival congestion, corneal nebula, pathogenic wind-warm arthralgia pain, contracture numbness, wind leprosy, furuncle, scabies, skin pruritus, hemorrhoid, dysentery.
Radix Cynanchi Atrati: [process of preparing Chinese medicine] decontamination, cleans, runs through, cutting, drying.[nature and flavor] are bitter, salty, cold.[return through] returns stomach, liver, kidney channel.[function cures mainly] clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome, detoxification sore treatment.For pathogenic warmth wound battalion heating, fever due to yin deficiency, hectic fever due to YIN-deficiency consumptive fever, puerperal fever due to deficiency of blood, pyretic stranguria, stranguria with blood, swollen ulcer drug.
Rhizoma Polygoni Cuspidati: [process of preparing Chinese medicine] removing impurity, cleans, runs through, cut sheet, dry.[nature and flavor] micro-hardship, is slightly cold.[return through] returns liver, gallbladder, lung meridian.[function cures mainly] expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, lump in the abdomen, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus, cough with copious phlegm.
Alkalium: [source] medical material Ji Yuan: be the lixivia extracted from the plant ash such as Artemisia, knotweed, and with flour, the solid processed from strand.[nature and flavor] salty hardship, arduous, temperature, micro-poison is pungent puckery, cold.[return through] stomach, large intestine channel.[function cures mainly] softening the hard mass, removing food stagnancy, dispelling phlegm and eliminating dampness, removing nebula.Cure mainly long-pending block, dysphagia and regurgitation, corneal nebula, warty vegetation.
Sorghum vulgare Pers.: [nature and flavor] sweet in the mouth; Cold nature.[return through] lung; Stomach; Large intestine channel.[function cures mainly] expelling wind and removing dampness; Stomach function regulating is calmed the nerves; Removing toxic substances sore.Main malaria cold and heat; Muscles and bones contraction is anxious; Dysentery; Uneasy sleeping at night; Toxic swelling; Dermatitis rhus; Chilblain; Lyssodexis.
Chinese medicine composition of the present invention is active component by Herba boeae clarkeanae, Herba Chenopodii Hybridi, Herba Onychii japonici, Herba Xanthii, Radix Cynanchi Atrati, Rhizoma Polygoni Cuspidati, alkalium, Sorghum vulgare Pers. or its water and/or its extractive with organic solvent or its volatile oil, adds pharmaceutically acceptable adjuvant and be prepared into pharmaceutically conventional exterior-applied formulation.As: unguentum, ointment, emulsifiable paste, powder, lotion, liniment, spray etc.
Preferably, Chinese medicine composition of the present invention makes unguentum.
Present invention also offers the preparation method that the Chinese medicinal ointment of malicious decomposed type decubital ulcer is accumulate in a kind for the treatment of, it is characterized in that comprising the following steps: by Herba boeae clarkeanae, Herba Chenopodii Hybridi, Herba Onychii japonici, Herba Xanthii, Radix Cynanchi Atrati, Rhizoma Polygoni Cuspidati, pulverize, decoct with water secondary, first time add water into medical material weight portion 5-8 doubly, decoct 0.5-1.0 hour, second time add water into medical material weight portion 3-4 doubly, decoct 1.0-1.5 hour, collecting decoction, filter, filtrate reduced in volume to relative density is 1.05-1.10 (80 DEG C of survey), adding ethanol makes alcohol content reach 50%, leave standstill 12 hours, filter, after filtrate recycling ethanol, concentrating under reduced pressure becomes dry extract, be ground into 80-100 order fine powder for subsequent use, get alkalium, Sorghum vulgare Pers. drying, pulverize, cross 500 mesh sieves for subsequent use, by above-mentioned gained fine powder mix homogeneously, be mixed and made into paste with adjuvant and get final product.
Described adjuvant is Oleum Brassicae campestris, and the weight ratio of medicated powder and Oleum Brassicae campestris is 1:3.5.
Using method: if fresh wound surface, can debridement, with povidone iodine or alcohol disinfecting surrounding skin, Chinese medicinal ointment cotton swab is applied in affected part, is then covered by ointment with gauze, in order to avoid make dirty clothes or bedding; If wound surface slough and secretions more time, wound surface slough need be rejected, remove purulent secretion, after routine disinfection, then use.7 days courses for the treatment of.
The present invention adopts natural raw material of Chinese medicine, follow the prescriptions principle of the traditional Chinese medical science, full side has effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, the evacuation of pus of holder skin ulcer, damp eliminating granulation promoting, subduing swelling and relieving pain, for accumulateing malicious decomposed type decubital ulcer, good effect, instant effect, short treating period, alleviates the labor intensity of patient's misery and nursing staff; And patient is acceptant, be applicable to hospital and the use of family therapy decubital ulcer.Through clinical practice checking, can more than 90% be reached for accumulateing malicious decomposed type decubital ulcer effective percentage.
Detailed description of the invention
Further describe the present invention below by way of detailed description of the invention, but the present invention is not limited only to following examples.Within the scope of the invention or not departing from content of the present invention, spirit and scope, Chinese medicine preparation of the present invention is suitably improved, replaces the identical component of effect, will become apparent to those skilled in the art that they are all deemed to be included within scope of the present invention.
Embodiment 1
Prescription: Herba boeae clarkeanae 24 parts, Herba Chenopodii Hybridi 15 parts, Herba Onychii japonici 17 parts, Herba Xanthii 7 parts, Radix Cynanchi Atrati 8 parts, Rhizoma Polygoni Cuspidati 10 parts, alkalium 5 parts, Sorghum vulgare Pers. 9 parts.
Preparation method: by Herba boeae clarkeanae, Herba Chenopodii Hybridi, Herba Onychii japonici, Herba Xanthii, Radix Cynanchi Atrati, Rhizoma Polygoni Cuspidati, pulverizing, decoct with water secondary, first time 6 times of adding water as medical material weight portion, decoct 0.5-1.0 hour, second time 4 times of adding water as medical material weight portion, decoct 1.0-1.5 hour, collecting decoction, filter, filtrate reduced in volume to relative density is 1.07 (80 DEG C of surveys), adds ethanol and makes alcohol content reach 50%, leave standstill 12 hours, filter, after filtrate recycling ethanol, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get alkalium, Sorghum vulgare Pers. drying, pulverize, cross 500 mesh sieves for subsequent use; By above-mentioned gained fine powder mix homogeneously, be that 1:3.5 is mixed homogeneously and made unguentum with Oleum Brassicae campestris according to weight ratio.
Embodiment 2
Prescription: Herba boeae clarkeanae 25 parts, Herba Chenopodii Hybridi 17 parts, Herba Onychii japonici 20 parts, Herba Xanthii 8 parts, Radix Cynanchi Atrati 10 parts, Rhizoma Polygoni Cuspidati 12 parts, alkalium 5 parts, Sorghum vulgare Pers. 10 parts.
Preparation method: by Herba boeae clarkeanae, Herba Chenopodii Hybridi, Herba Onychii japonici, Herba Xanthii, Radix Cynanchi Atrati, Rhizoma Polygoni Cuspidati, pulverizing, decoct with water secondary, first time add water into medical material weight portion 5-8 doubly, decoct 0.5-1.0 hour, second time add water into medical material weight portion 3-4 doubly, decoct 1.0-1.5 hour, collecting decoction, filter, filtrate reduced in volume to relative density is 1.08 (80 DEG C of surveys), adds ethanol and makes alcohol content reach 50%, leave standstill 12 hours, filter, after filtrate recycling ethanol, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get alkalium, Sorghum vulgare Pers. drying, pulverize, cross 500 mesh sieves for subsequent use; By above-mentioned gained fine powder mix homogeneously, be that 1:3.5 is mixed homogeneously and made unguentum with Oleum Brassicae campestris according to weight ratio.
Embodiment 3
Prescription: Herba boeae clarkeanae 21 parts, Herba Chenopodii Hybridi 13 parts, Herba Onychii japonici 15 parts, Herba Xanthii 7 parts, Radix Cynanchi Atrati 10 parts, Rhizoma Polygoni Cuspidati 12 parts, alkalium 6 parts, Sorghum vulgare Pers. 7 parts.
Preparation method: by Herba boeae clarkeanae, Herba Chenopodii Hybridi, Herba Onychii japonici, Herba Xanthii, Radix Cynanchi Atrati, Rhizoma Polygoni Cuspidati, pulverizing, decoct with water secondary, first time 5 times of adding water as medical material weight portion, decoct 0.5-1.0 hour, second time 3 times of adding water as medical material weight portion, decoct 1.0-1.5 hour, collecting decoction, filter, filtrate reduced in volume to relative density is 1.05 (80 DEG C of surveys), adds ethanol and makes alcohol content reach 50%, leave standstill 12 hours, filter, after filtrate recycling ethanol, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get alkalium, Sorghum vulgare Pers. drying, pulverize, cross 500 mesh sieves for subsequent use; By above-mentioned gained fine powder mix homogeneously, be that 1:3.5 is mixed homogeneously and made unguentum with Oleum Brassicae campestris according to weight ratio.
Embodiment 4
Prescription: Herba boeae clarkeanae 26 parts, Herba Chenopodii Hybridi 14 parts, Herba Onychii japonici 18 parts, Herba Xanthii 9 parts, Radix Cynanchi Atrati 10 parts, Rhizoma Polygoni Cuspidati 12 parts, alkalium 4 parts, Sorghum vulgare Pers. 8 parts.
Preparation method: by Herba boeae clarkeanae, Herba Chenopodii Hybridi, Herba Onychii japonici, Herba Xanthii, Radix Cynanchi Atrati, Rhizoma Polygoni Cuspidati, pulverizing, decoct with water secondary, first time 8 times of adding water as medical material weight portion, decoct 0.5-1.0 hour, second time 4 times of adding water as medical material weight portion, decoct 1.0-1.5 hour, collecting decoction, filter, filtrate reduced in volume to relative density is 1.10 (80 DEG C of surveys), adds ethanol and makes alcohol content reach 50%, leave standstill 12 hours, filter, after filtrate recycling ethanol, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get alkalium, Sorghum vulgare Pers. drying, pulverize, cross 500 mesh sieves for subsequent use; By above-mentioned gained fine powder mix homogeneously, be that 1:3.5 is mixed homogeneously and made unguentum with Oleum Brassicae campestris according to weight ratio.
Embodiment 5
Prescription: Herba boeae clarkeanae 27 parts, Herba Chenopodii Hybridi 13 parts, Herba Onychii japonici 18 parts, Herba Xanthii 8 parts, Radix Cynanchi Atrati 12 parts, Rhizoma Polygoni Cuspidati 14 parts, alkalium 7 parts, Sorghum vulgare Pers. 11 parts.
Preparation method: by Herba boeae clarkeanae, Herba Chenopodii Hybridi, Herba Onychii japonici, Herba Xanthii, Radix Cynanchi Atrati, Rhizoma Polygoni Cuspidati, pulverizing, decoct with water secondary, first time 8 times of adding water as medical material weight portion, decoct 0.5-1.0 hour, second time 4 times of adding water as medical material weight portion, decoct 1.0-1.5 hour, collecting decoction, filter, filtrate reduced in volume to relative density is 1.07 (80 DEG C of surveys), adds ethanol and makes alcohol content reach 50%, leave standstill 12 hours, filter, after filtrate recycling ethanol, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get alkalium, Sorghum vulgare Pers. drying, pulverize, cross 500 mesh sieves for subsequent use; By above-mentioned gained fine powder mix homogeneously, be that 1:3.5 is mixed homogeneously and made unguentum with Oleum Brassicae campestris according to weight ratio.
Embodiment 6 clinical observation is tested
1. physical data: this is organized 150 routine patients and is to bring into outside in January, 2013-December institute and accumulates malicious decomposed type decubital ulcer, man 66 example, female 84 example; Age between 57 ~ 85, average (67.9 ± 6.5) year; Protopathy comprises the common complication of other sections paralysis such as fracture is rear, diabetes, apoplexy sequela, chronic obstructive pneumonia and long-term bedridden patients, the maximum 15cm × 18cm of decubital ulcer area, minimum 3cm × 4cm, average (45.96 ± 6.48) cm
2.Be divided into treatment group and matched group at random by 1:1, the item indexs such as two groups of Genders, age, decubitus ulcer areas, through statistical procedures no significant difference, have comparability (P > 0.05).
2. diagnostic criteria is according to the formulation of " People's Republic of China's traditional Chinese medicine industry standard--Chinese medical disease Standardization of diagnosis and curative effect (YZ/T001.1-94) " decubital ulcer: be apt to occur in the apophysis such as tail sacrum, ridge, elbow ankle and easily suffer oppression and the position that rubs; From the beginning of skin occurring brown erythema, micro-swollen, purple dark edema then, necrosis is festered; During secondary contamination, tissue necrosis is rapid, and pus is dripping, corresponding site Bing Fa Xing core pain; Be more common in the patient of the prolonged illness beds such as stupor, paralysis, fracture, large-area burns;
3. tcm syndrome classification accumulates malicious decomposed card according to the formulation of " People's Republic of China's traditional Chinese medicine industry standard--Chinese medical disease Standardization of diagnosis and curative effect (YZ/T001.1-94) " decubital ulcer: decubital ulcer is festered, slough and pus more, or foul smelling, severe one is festered can deeply and muscles and bones, and surrounding is unrestrained swollen.With heating or low grade fever, bitter taste and dry, body and the spirit is dispirited, anorexia etc.Red tongue, tongue is few, thready and rapid pulse.
4. treatment and care method
4.1. care method: all patients all use air fluidized bed to alleviate local compression, and 1 ~ 2h stands up once, lifts patient when standing up as far as possible, the action such as avoids pushing away, drags, draws, to prevent scratch mark; Keep bed clean, smooth, dry, avoid the long-term pressurized of pressure ulcer wound surface, carry out outside above-mentioned nursery work, use antibiotic according to the state of an illness, Cure the Primary Disease, strengthen diet nursing, improve nutrition of whole body situation, improve Abwehrkraft des Koepers, prevent secondary infection.
4.2. Therapeutic Method:
Matched group: application traditional remedies treatment.First clean wound surface with hydrogen peroxide, iodophor disinfection, remove slough as far as possible, reach that wound surface is fresh ruddyly hemorrhagely to be enriched for standard, then with 0.9% sodium chloride injection cleaning, iodophor disinfection, sterile gauze covers, every day 1 time, 7 days courses for the treatment of.
Treatment group: the paste application embodiment of the present invention 1 prepared on treatment of control group basis is on wound surface, and external application sterile gauze, changes dressings 1 every day.
5. efficacy evaluation is according to the formulation of " People's Republic of China's traditional Chinese medicine industry standard--Chinese medical disease Standardization of diagnosis and curative effect (YZ/T001.1-94) " decubital ulcer: cure: brown erythema disappears, or the wound healing that festers; Take a turn for the better: erythema does not disappear entirely, or the skin ulcer face slough that festers comes off, granulation, and skin ulcer face reduces gradually; Do not heal: the open sore part increases, fester more than.
6. statistical analysis: adopt SPSS17.0 statistical software to carry out statistical analysis, measurement data adopts t inspection, with mean ± standard deviation
represent, data of equal value compares employing X
2inspection, with P < 0.05 for difference has statistical significance.
7. result
7.1. two groups of Clinical efficacy comparisons after two courses for the treatment of: treatment group cures 27 examples, take a turn for the better 42 examples, and do not heal 6 examples, total effective rate 92.0%; Matched group cures 13 examples, and take a turn for the better 36 examples, and do not heal 26 examples, and total effective rate 65.3%, two groups of cure rates and total effective rate comparing difference have statistical significance (P < 0.05), and treatment group curative effect is obviously better than matched group, in table 1.
Two groups of Clinical efficacy comparisons after two courses for the treatment of of table 1: example (%)
7.2. two groups of Clinical efficacy comparisons after three courses for the treatment of: treatment group cures 55 examples, take a turn for the better 19 examples, and do not heal 1 example, total effective rate 98.7%; Matched group cures 32 examples, and take a turn for the better 32 examples, and do not heal 11 examples, and total effective rate 85.3%, two groups of cure rates and total effective rate comparing difference have statistical significance (P < 0.05), and treatment group curative effect is obviously better than matched group, in table 2.
Two groups of Clinical efficacy comparisons after two courses for the treatment of of table 2: example (%)
7.3. after three courses for the treatment of, the healing time of two groups compares: the healing time for the treatment of group patient is (10.3 ± 3.7) d; The healing time of matched group patient is (14.3 ± 5.2) d, and treatment group healing time is significantly shorter than matched group, and difference has statistical significance (P < 0.05).
Can find that treatment group is apparently higher than matched group by the healing time of the treatment cure rate and total effective rate and healing patient that contrast two groups of patients, illustrate thus, the present invention accumulates malicious decomposed type decubital ulcer in treatment and has good clinical effectiveness, effectively can improve the cure rate for the treatment of, be worth promoting in clinical practice.
Model case: Wang, man, 69 years old, due to disease long-term bed, tail sacrum bedsore festered, slough and pus more, or foul smelling, severe one is festered can deeply and muscles and bones, and surrounding is unrestrained to swell; With heating or low grade fever, bitter taste and dry, lethargy, anorexia; Red tongue, tongue is few, thready and rapid pulse, is diagnosed as and accumulates malicious decomposed type decubital ulcer.After using two courses for the treatment of of unguentum of Chinese medicine preparation embodiment 2 of the present invention, affected part is clearly better, and continues 1 course for the treatment of of use, substantially to cure, follow up a case by regular visits to and do not recur half a year.
Claims (7)
1. a Chinese medicine composition for malicious decomposed type decubital ulcer is accumulate in treatment, it is characterized in that it is made up of eight taste Chinese herbal medicine such as Herba boeae clarkeanae, Herba Chenopodii Hybridi, Herba Onychii japonici, Herba Xanthii, Radix Cynanchi Atrati, Rhizoma Polygoni Cuspidati, alkalium, Sorghum vulgare Pers.s.
2. Chinese medicine composition as claimed in claim 1, is characterized in that it is made up of the Chinese herbal medicine of following preferred weight part: Herba boeae clarkeanae 21-27 part, Herba Chenopodii Hybridi 13-18 part, Herba Onychii japonici 15-20 part, Herba Xanthii 6-9 part, Radix Cynanchi Atrati 7-12 part, Rhizoma Polygoni Cuspidati 9-14 part, alkalium 4-7 part, Sorghum vulgare Pers. 7-11 part.
3. Chinese medicine composition as claimed in claim 2, is characterized in that it is made up of the Chinese herbal medicine of following preferred weight part: Herba boeae clarkeanae 24 parts, Herba Chenopodii Hybridi 15 parts, Herba Onychii japonici 17 parts, Herba Xanthii 7 parts, Radix Cynanchi Atrati 8 parts, Rhizoma Polygoni Cuspidati 10 parts, alkalium 5 parts, Sorghum vulgare Pers. 9 parts.
4. Chinese medicine composition as claimed in claim 2, is characterized in that it is made up of the Chinese herbal medicine of following preferred weight part: Herba boeae clarkeanae 25 parts, Herba Chenopodii Hybridi 17 parts, Herba Onychii japonici 20 parts, Herba Xanthii 8 parts, Radix Cynanchi Atrati 10 parts, Rhizoma Polygoni Cuspidati 12 parts, alkalium 5 parts, Sorghum vulgare Pers. 10 parts.
5. the Chinese medicine composition as described in claim 1-4, is characterized in that it is prepared into pharmaceutically conventional exterior-applied formulation.As: unguentum, ointment, emulsifiable paste, powder, lotion, liniment, spray etc.
6. Chinese medicine composition as claimed in claim 5, is characterized in that the preferred unguentum of described exterior-applied formulation.
7. the Chinese medicine composition as described in claim 1-6, it is characterized in that the preparation method of described unguentum comprises the following steps: by Herba boeae clarkeanae, Herba Chenopodii Hybridi, Herba Onychii japonici, Herba Xanthii, Radix Cynanchi Atrati, Rhizoma Polygoni Cuspidati, pulverize, decoct with water secondary, first time add water into medical material weight portion 5-8 doubly, decoct 0.5-1.0 hour, second time add water into medical material weight portion 3-4 doubly, decoct 1.0-1.5 hour, collecting decoction, filter, filtrate reduced in volume to relative density is 1.05-1.10 (80 DEG C of survey), adding ethanol makes alcohol content reach 50%, leave standstill 12 hours, filter, after filtrate recycling ethanol, concentrating under reduced pressure becomes dry extract, be ground into 80-100 order fine powder for subsequent use, get alkalium, Sorghum vulgare Pers. drying, pulverize, cross 500 mesh sieves for subsequent use, by above-mentioned gained fine powder mix homogeneously, be mixed and made into paste with adjuvant and get final product.Described adjuvant is Oleum Brassicae campestris, and the weight ratio of medicated powder and Oleum Brassicae campestris is 1:3.5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510446338.4A CN104958613B (en) | 2015-07-27 | 2015-07-27 | Chinese medicine composition of malicious decomposed type decubital ulcer and preparation method thereof is accumulate in a kind for the treatment of |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510446338.4A CN104958613B (en) | 2015-07-27 | 2015-07-27 | Chinese medicine composition of malicious decomposed type decubital ulcer and preparation method thereof is accumulate in a kind for the treatment of |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104958613A true CN104958613A (en) | 2015-10-07 |
| CN104958613B CN104958613B (en) | 2016-04-06 |
Family
ID=54212815
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510446338.4A Active CN104958613B (en) | 2015-07-27 | 2015-07-27 | Chinese medicine composition of malicious decomposed type decubital ulcer and preparation method thereof is accumulate in a kind for the treatment of |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104958613B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511825A (en) * | 2017-01-17 | 2017-03-22 | 段修英 | Traditional Chinese medicine for bedsore nursing |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927292A (en) * | 2006-09-05 | 2007-03-14 | 伍建华 | External use drug for treating burn, bedsore, chronic ulcer and etc. and preparation method thereof |
| CN102416084A (en) * | 2011-11-25 | 2012-04-18 | 冯云萍 | Externally applied drug for treating bedsores, burns and scalds |
-
2015
- 2015-07-27 CN CN201510446338.4A patent/CN104958613B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1927292A (en) * | 2006-09-05 | 2007-03-14 | 伍建华 | External use drug for treating burn, bedsore, chronic ulcer and etc. and preparation method thereof |
| CN102416084A (en) * | 2011-11-25 | 2012-04-18 | 冯云萍 | Externally applied drug for treating bedsores, burns and scalds |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511825A (en) * | 2017-01-17 | 2017-03-22 | 段修英 | Traditional Chinese medicine for bedsore nursing |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104958613B (en) | 2016-04-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104352587A (en) | Ointment for treating rhinitis | |
| CN104958613B (en) | Chinese medicine composition of malicious decomposed type decubital ulcer and preparation method thereof is accumulate in a kind for the treatment of | |
| CN103638316B (en) | Traditional Chinese medicine preparation for treating dermatitis | |
| CN103263614B (en) | Pharmaceutical composition for preventing or treating vaginitis | |
| CN105079332A (en) | Traditional Chinese medicine composition for treating perianal abscess caused by fire toxin accumulation | |
| CN106389620B (en) | It is a kind of for treating the Washout traditional Chinese medicine composition of perianal eczema | |
| CN104958395A (en) | Traditional Chinese medicine composition for treating cold-with-dampness type cough | |
| CN103977254A (en) | Traditional Chinese medicine preparation for treating infant suppurative tonsillitis and nursing method thereof | |
| CN105168625B (en) | A kind of clinical care is used for the treatment of the Chinese medicine liniment of two, three phase decubital ulcers | |
| CN104013950A (en) | Traditional Chinese medicine composition for treating toxin and decay type bedsore and preparation method of composition | |
| CN103285339B (en) | External medicine for treating bone pain disease | |
| CN103520638B (en) | A kind of Traditional Chinese medicine compound composition for the treatment of prostate hyperplasia and preparation method thereof and application thereof | |
| CN103341151B (en) | Traditional Chinese medicine for treating chronic bronchitis | |
| CN104491104A (en) | Traditional Chinese medicine composition for treating bedsore in clinical care | |
| CN102366574A (en) | Externally applied Chinese herbal powder for treating beriberi | |
| CN105055506A (en) | Traditional Chinese medicine ointment used for treating terminal bedsore in clinical care | |
| CN103893509B (en) | A kind of medicine for the treatment of of allergic rhinitis and preparation method | |
| CN106166209A (en) | For promoting I phase, II phase pressure ulcer healing, the antiinfectious powder of Bedsore prevention III phase | |
| CN105999131B (en) | A kind of Externally-applied Zhuang medicine composition for treating chronic prostatitis | |
| CN104940635A (en) | Scald and burn traditional Chinese medicine compound for external use | |
| CN105168847A (en) | Traditional Chinese medicine for treating helicobacter pylori infected peptic ulcer | |
| CN104491327A (en) | Spraying agent for treating bedsore | |
| CN104825939A (en) | Traditional Chinese medicine preparation for treating lumbar muscle strain | |
| CN104001082A (en) | Traditional Chinese medicine for treating damp-heat stasis type kidney calculi | |
| CN104707124A (en) | Traditional Chinese medicine preparation for treating chronic endometritis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Li Haiyun Inventor before: The inventor has waived the right to be mentioned |
|
| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160311 Address after: Yizhou road 276000 Shandong city of Linyi province Lanshan District 174-2 No. 2 ranked No. 2 Applicant after: Li Haiyun Address before: 266109 Shandong, Qingdao, Chengyang District, No. 825 Zhengyang Road, building, room 1, office, room 205 Applicant before: The skies, Qingdao Bioisystech Co., Ltd |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20171204 Address after: No. 999, 216100 West Avenue, Binhai New Area, Haimen, Nantong, Jiangsu Patentee after: HAIMEN HUANGHAI PIONEER PARK SERVICES CO., LTD. Address before: Yizhou road 276000 Shandong city of Linyi province Lanshan District 174-2 No. 2 ranked No. 2 Patentee before: Li Haiyun |