CN104491327A - Spraying agent for treating bedsore - Google Patents

Spraying agent for treating bedsore Download PDF

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Publication number
CN104491327A
CN104491327A CN201410747528.5A CN201410747528A CN104491327A CN 104491327 A CN104491327 A CN 104491327A CN 201410747528 A CN201410747528 A CN 201410747528A CN 104491327 A CN104491327 A CN 104491327A
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parts
semen strychni
raw material
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CN104491327B (en
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茅金宝
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Shandong Provincial Hospital
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Shandong Provincial Hospital
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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Abstract

The invention provides a spraying agent for treating bedsore. The spraying agent is prepared from the following finely selected natural traditional Chinese medicinal materials: teasel root, dragon's blood, origanum vulgare, radix notoginseng, safflower, prepared semen strychni, amber, herba lycopi, sappan wood, aloe, herba orostachyos and true lacquertree leaves and the like. The spraying agent disclosed by the invention is convenient to use just by spraying, and can be used for clearing away heat and toxic materials, removing slough and promoting growth of tissue regeneration, and therefore the spraying agent brings good news for treating bedsore of long-term bedridden patients.

Description

A kind of spraying medicament being used for the treatment of decubital ulcer
Invention field
The present invention relates to the field of Chinese medicines, particularly relate to a kind of spraying medicament being used for the treatment of the second stage of inflammatory infiltration phase pressure ulcer and the either shallow ulcerative stage pressure ulcer of three phases.
Background technology
Decubital ulcer is also known as pressure ulcer, human skin tissue suffers oppression for a long time and health stir improper etc. cause friction, shearing force, blood circulation is obstructed and causes histanoxia, thus cause tissue injury and necrosis, to deep development can involve periosteum even sclerotin cause focal periostitis or osteomyelitis.Be mainly in the patient of paralysis, hemiplegia, paraplegia, cerebral palsy, and the patient of stupor, the patient of gatism, old people and malnutrition, health are languisher.After decubital ulcer is developed to and produces inflammation, venous congestion, subcutaneous induration edema, can have blister to produce.Clinical simple routine care, as Turn the body over and massage etc., unsatisfactory curative effect all.External iodine tincture or injection of antibiotics etc., healing is slow easily repeatedly; Cream, medicine oil easily pollute bedding, use inconvenience, use to smear in process to be easily infected with pathogenic bacteria and to cause superinfection.If nursing for treating is improper, secondary infection ulcer, finally can cause decubital ulcer complication to cause death.
Summary of the invention
For solveing the technical problem, reach heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, antiinflammatory analgesic therapy by treating decubital ulcer simply and easily, removing the necrotic tissue and promoting granulation, the object not easily recurred, the following technical scheme of the invention process:
Be used for the treatment of a spraying medicament for decubital ulcer, the raw material containing Effective Component of Chinese Medicine forms and weight fraction is: Radix Dipsaci 16 ~ 32 parts, Sanguis Draxonis 4 ~ 6 parts, Adeps Bovis seu Bubali 30 ~ 52 parts, 6 ~ 18 parts, Radix Notoginseng, 8 ~ 20 parts, Flos Carthami, Semen Strychni (processed) 2 ~ 4 parts, succinum 6 ~ 12 parts, Herba Lycopi 12 ~ 20 parts, Lignum Sappan 12 ~ 20 parts, Aloe 3 ~ 8 parts, Herba Orostachyos 11 ~ 30 parts, Folium toxicodendri verniciflni 6 ~ 18 parts.
Preferably, be used for the treatment of a spraying medicament for decubital ulcer, the raw material containing Effective Component of Chinese Medicine forms and weight fraction is: Radix Dipsaci 24 parts, Sanguis Draxonis 5 parts, Adeps Bovis seu Bubali 40 parts, 12 parts, Radix Notoginseng, 14 parts, Flos Carthami, Semen Strychni (processed) 3 parts, succinum 9 parts, Herba Lycopi 16 parts, Lignum Sappan 16 parts, Aloe 6 parts, Herba Orostachyos 20 parts, Folium toxicodendri verniciflni 12 parts.
Described decubital ulcer is, the second stage of inflammatory infiltration phase pressure ulcer and the either shallow ulcerative stage pressure ulcer of three phases.
Be used for the treatment of a spraying medicament for decubital ulcer, preparation comprises following processing step:
(1) put in pot by fine sand, intense fire is fried to about 190 DEG C, adds clean Semen Strychni, stirs, and fries to heaving in brown, takes out, removes sand, cool to obtain Semen Strychni (processed), for subsequent use.
(2) take Sanguis Draxonis, Radix Notoginseng and succinum by raw material weight proportioning, remove impurity, mixing is broken, grinds to obtain fine powder, crosses 100 mesh sieves, for subsequent use.
(3) take step (1) gained Semen Strychni (processed) and Radix Dipsaci, Adeps Bovis seu Bubali, Flos Carthami, Herba Lycopi, Lignum Sappan, Aloe, Herba Orostachyos, Folium toxicodendri verniciflni by raw material weight proportioning, pulverize together, add the yellow wine of five times of weight, after boiling, continue immersion 2 ~ 3 hours, filter, get and boil liquid; In remaining medicinal residues, add the yellow wine of treble amount again, boil rear continuation immersion 1 ~ 2 hour, filter, get and boil liquid; Merge twice gained and boil liquid, filter, heating distillation and concentration to 3 ~ 4 times of crude drug weight, in raw material weight, take step (2) gained fine powder by proportioning, the heat slowly added after concentrating is boiled in liquid, stirs, soak 2 ~ 3 hours, again filter to get filtrate, for subsequent use.
(4) filtrate of step (3) gained is added ethanol, stirring and evenly mixing, be configured as the spraying medicament containing weight ratio 25 ~ 40% ethanol, fill.
The property of medicine of the present invention's Chinese medicine used is: Radix Dipsaci: slightly warm in nature.Bone and muscle strengthening, blood circulation regulating.Cure mainly fall flutter wound, damage muscle folding bone, carbuncle skin ulcer swell." herbal classic " carries: " folding falls, reuniting the fractured tendons and bones for main incised wound, carbuncle and ulcer ".Modern medicine study confirms, Radix Dipsaci has the effect of evacuation of pus, hemostasis, analgesia, promotion tissue regeneration to carbuncle and ulcer.Sanguis Draxonis: external can hemostasia and promoting granulation, and sore, controls ecthyma unhealed for long time.Modern medicine study confirms, Sanguis Draxonis has inhibitory action in various degree to multiple pathomycetes such as oidium schoenleiniis, and can significantly shorten plasma in rabbit recalcification time, thus increases its Blood clotting.Adeps Bovis seu Bubali: acrid in the mouth, cool in nature.Detoxicating, relieving inflammation, promoting diuresis and easing pain.Modern medicine study confirms, Adeps Bovis seu Bubali is inhibited to various bacteria such as shigella flexneri, bacterium sonnei, staphylococcus aureuses, and peritoneal macrophage phagocytic index and phagocytic rate can be significantly improved and the specific humoral immunity function that is index with amboceptor reaction, improve immunity.Radix Notoginseng: hemostasis, nourishes blood, loose blood, analgesic therapy.Cure mainly to fall and flutter congestive edema, mass in the abdomen, sore, carbuncle and painful swelling.Modern medicine study confirms, Radix Notoginseng can increase platelet count, promotes blood coagulation; Significantly improve phagocytic rate and the phagocytic index of Turnover of Mouse Peritoneal Macrophages; Improve the mice threshold of pain; And contained Radix Notoginseng fibrous root Total saponin has antiulcer action, improve hematopoietic stem cell active.Flos Carthami: warm in nature.Invigorating blood circulation can be through; Stasis-dispelling and pain-killing.Cure mainly dysfunction of the urinary bladder pained; Lumps in the chest and abdomen; Traumatic injury; Arthralgia.Modern medicine study confirms, Flos Carthami can increase the penetrating amount of capillary of skin, anti-inflammatory and antalgic, strengthens the central inhibitory action of barbital and chloral hydrate; Strengthen immunologic cellular activity.Semen Strychni (processed): dredging collateral; Strong muscle; Eliminating stagnation; Pain relieving; Detumescence; Removing toxic substances.Cure mainly rheumatic arthralgia; Numbness of the skin; Quadriplegia; Traumatic injury; Fracture swells and ache; Skin sore.Modern medicine study confirms: the water decoction of Semen Strychni (processed) is in vitro to oidium schoenleinii, and Microsporon audouini has inhibitory action in various degree.Succinum: property is put down, nontoxic.Can tranquillizing the mind by relieving convulsion; Dissipating blood stasis stops blooding.Modern medicine confirms, succinic acid contained by succinum has inhibitory action and antiulcer action when 2mg/ml concentration to staphylococcus aureus, micrococcus catarrhalis and typhoid fever, green pus, distortion, dysentery bacterium.Herba Lycopi: be labiate hair leaf Rhizoma Lycopi Lucidi aerial parts after drying, slightly warm in nature.Energy blood circulation promoting and blood stasis dispelling, line water detumescence.Modern medicine study confirms, Herba Lycopi can make weightlessness in simulation space travel cause the rabbit of blood stasis obviously to improve microcirculation disturbance, also has a better role to the hemorheology of rabbit exception.Lignum Sappan: property is pungent cool.Blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain.Modern medicine study confirms, Lignum Sappan decocting alcohol extract can significantly promote arteriole blood flow, promotes the recovery of microcirculation and caliber; Lignum Sappan mixture and decoct have stronger bacteriostasis to various bacteria such as staphylococcus aureus, Hemolytic streptococcus and paratyphoid fever bacillus in vitro, also have inhibitory action to bordetella pertussis, Bacillus typhi and pneumobacillus.Aloe: cold in nature.Heat clearing away, parasite killing.Modern medicine study confirms, with Aloe soaking object (10% solution) in the rabbit of artificial conjunctiva edema, can shorten curative day; The Mus of artificial wound is carried on the back, also has the effect of slight Promotive union; Decoct has inhibitory action in various degree to dermatophytess such as epidermophyton inguinale, epidermophyton rubrum, star nocardias.Herba Orostachyos: energy cooling blood for hemostasis; Heat-clearing and toxic substances removing; Removing dampness sword skin ulcer.Folium toxicodendri verniciflni: acrid in the mouth is warm in nature.Promoting blood circulation and detoxication; Parasite killing sore." Luchuan book on Chinese herbal medicine " carries: " control traumatic hemorrhage, carbuncle sore festers.Life is smash deposited.”
The selected good recipe of the present invention, with heat-clearing and toxic substances removing, hemostasis dissipating blood stasis, anti-inflammation is means, reaches detumescence and relieves the pain, putrefaction-removing granulation-promoting, suppresses the therapeutic purposes of recurrence.In side, Semen Strychni (processed), Lignum Sappan, Aloe, Herba Orostachyos, Folium toxicodendri verniciflni is compatible, mutually to assist a ruler in governing a country, heat-clearing and toxic substances removing, bactericidal, to suppress pathogenic bacterium regeneration; Adeps Bovis seu Bubali, Radix Notoginseng, Flos Carthami are compatible, can immunity moderation system, strengthen human immunity vigor; Two sides group mutually, treating both the principal and secondary aspects of a disease, inside and outside be harmonious, the effect effectively reducing recurrent infection can be played.Semen Strychni (processed), Radix Notoginseng, Herba Lycopi, Lignum Sappan are compatible, can dredging collateral dissipating blood stasis, detumescence relieve the pain; Radix Dipsaci, Sanguis Draxonis, succinum, Radix Notoginseng are helped mutually, can stop blooding nourish blood, putrefaction-removing granulation-promoting; Two sides group mutually, can fall apart to mend combines, and controls skin ulcer and presses down ulcer.All medicine compatibilities, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, heat-clearing and toxic substances removing, again not Wen Buhan, can improve microcirculation, and improve immunity, bactericidal, removing blood stasis and activating blood flow, putrefaction-removing granulation-promoting, anti-inflammation, stimulating menstrual flow and reducing pain, effectively prevents decubital ulcer from recurring; Accelerate patient's skin ulcer face to recover, reduce the risk of recurrence further, remarkable through clinical efficacy, be suitable for resuming treatment of decubital ulcer.
The preparation method provided is simple, reasonable in design.Prescription Chinese medicine is made as alcoholic external spraying medicament, strengthens Chinese Herbs, alleviate drug side effect, avoid the impact of the intestines and stomach absorption on endo-medicine drug effect.Spraying medicament is easy to use simultaneously, and instant effect, good absorbing, does not pollute bedding, is convenient to patient's life-time service.
Detailed description of the invention
Below in conjunction with embodiment and case, further explaination is done to the present invention.
Embodiment 1
A kind of spraying medicament being used for the treatment of decubital ulcer of the present invention, the raw material containing Effective Component of Chinese Medicine forms and weight fraction is: Radix Dipsaci 12 grams, Sanguis Draxonis 2.5 grams, Adeps Bovis seu Bubali 20 grams, 6 grams, Radix Notoginseng, 7 grams, Flos Carthami, Semen Strychni (processed) 1.5 grams, succinum 4.5 grams, Herba Lycopi 8 grams, Lignum Sappan 8 grams, Aloe 3 grams, Herba Orostachyos 10 grams, Folium toxicodendri verniciflni 6 grams.
Be used for the treatment of a spraying medicament for decubital ulcer, preparation comprises following processing step:
(1) put in pot by fine sand, intense fire is fried to about 190 DEG C, adds clean Semen Strychni, stirs, and fries to heaving in brown, takes out, removes sand, cool to obtain Semen Strychni (processed), for subsequent use.
(2) take Sanguis Draxonis, Radix Notoginseng and succinum by raw material weight proportioning, remove impurity, mixing is broken, grinds to obtain fine powder, crosses 100 mesh sieves, for subsequent use.
(3) take step (1) gained Semen Strychni (processed) and Radix Dipsaci, Adeps Bovis seu Bubali, Flos Carthami, Herba Lycopi, Lignum Sappan, Aloe, Herba Orostachyos, Folium toxicodendri verniciflni by raw material weight proportioning, pulverize together, add the yellow wine of five times of weight, after boiling, continue immersion 2.5 hours, filter, get and boil liquid; In remaining medicinal residues, add the yellow wine of treble amount again, boil rear continuation immersion 1.5 hours, filter, get and boil liquid; Merge twice gained and boil liquid, filter, heating distillation and concentration to 3 times of crude drug weight, in raw material weight, take step (2) gained fine powder by proportioning, the heat slowly added after concentrating is boiled in liquid, stirs, soak 2.5 hours, again filter to get filtrate, for subsequent use.
(4) filtrate of step (3) gained is added ethanol, stirring and evenly mixing, be configured as the spraying medicament containing weight ratio 30% ethanol, fill.
Usage and consumption are: in affected part external spraying, every day three times, at every turn every square centimeter spraying 2ml, bimester one course for the treatment of.
Embodiment 2
A kind of spraying medicament being used for the treatment of decubital ulcer of the present invention, the raw material containing Effective Component of Chinese Medicine forms and weight fraction is: Radix Dipsaci 16 grams, Sanguis Draxonis 4 grams, Adeps Bovis seu Bubali 45 grams, 15 grams, Radix Notoginseng, 20 grams, Flos Carthami, Semen Strychni (processed) 2 grams, succinum 10 grams, Herba Lycopi 12 grams, Lignum Sappan 20 grams, Aloe 8 grams, Herba Orostachyos 15 grams, Folium toxicodendri verniciflni 6 grams.
Be used for the treatment of a spraying medicament for decubital ulcer, preparation comprises following processing step:
(1) put in pot by fine sand, intense fire is fried to about 190 DEG C, adds clean Semen Strychni, stirs, and fries to heaving in brown, takes out, removes sand, cool to obtain Semen Strychni (processed), for subsequent use.
(2) take Sanguis Draxonis, Radix Notoginseng and succinum by raw material weight proportioning, remove impurity, mixing is broken, grinds to obtain fine powder, crosses 100 mesh sieves, for subsequent use.
(3) take step (1) gained Semen Strychni (processed) and Radix Dipsaci, Adeps Bovis seu Bubali, Flos Carthami, Herba Lycopi, Lignum Sappan, Aloe, Herba Orostachyos, Folium toxicodendri verniciflni by raw material weight proportioning, pulverize together, add the yellow wine of five times of weight, after boiling, continue immersion 2 hours, filter, get and boil liquid; In remaining medicinal residues, add the yellow wine of treble amount again, boil rear continuation immersion 1 hour, filter, get and boil liquid; Merge twice gained and boil liquid, filter, heating distillation and concentration to 4 times of crude drug weight, in raw material weight, take step (2) gained fine powder by proportioning, the heat slowly added after concentrating is boiled in liquid, stirs, soak 3 hours, again filter to get filtrate, for subsequent use.
(4) filtrate of step (3) gained is added ethanol, stirring and evenly mixing, be configured as the spraying medicament containing weight ratio 28% ethanol, fill.
Usage and consumption are: in affected part external spraying, every day three times, at every turn every square centimeter spraying 1ml, bimester one course for the treatment of.
Embodiment 3
A kind of spraying medicament being used for the treatment of decubital ulcer of the present invention, the raw material containing Effective Component of Chinese Medicine forms and weight fraction is: Radix Dipsaci 20 grams, Sanguis Draxonis 6 grams, Adeps Bovis seu Bubali 52 grams, 6 grams, Radix Notoginseng, 8 grams, Flos Carthami, Semen Strychni (processed) 3 grams, succinum 12 grams, Herba Lycopi 18 grams, Lignum Sappan 18 grams, Aloe 4 grams, Herba Orostachyos 30 grams, Folium toxicodendri verniciflni 18 grams.
Be used for the treatment of a spraying medicament for decubital ulcer, preparation comprises following processing step:
(1) put in pot by fine sand, intense fire is fried to about 190 DEG C, adds clean Semen Strychni, stirs, and fries to heaving in brown, takes out, removes sand, cool to obtain Semen Strychni (processed), for subsequent use.
(2) take Sanguis Draxonis, Radix Notoginseng and succinum by raw material weight proportioning, remove impurity, mixing is broken, grinds to obtain fine powder, crosses 100 mesh sieves, for subsequent use.
(3) take step (1) gained Semen Strychni (processed) and Radix Dipsaci, Adeps Bovis seu Bubali, Flos Carthami, Herba Lycopi, Lignum Sappan, Aloe, Herba Orostachyos, Folium toxicodendri verniciflni by raw material weight proportioning, pulverize together, add the yellow wine of five times of weight, after boiling, continue immersion 3 hours, filter, get and boil liquid; In remaining medicinal residues, add the yellow wine of treble amount again, boil rear continuation immersion 1.6 hours, filter, get and boil liquid; Merge twice gained and boil liquid, filter, heating distillation and concentration to 3.6 times of crude drug weight, in raw material weight, take step (2) gained fine powder by proportioning, the heat slowly added after concentrating is boiled in liquid, stirs, soak 2 hours, again filter to get filtrate, for subsequent use.
(4) filtrate of step (3) gained is added ethanol, stirring and evenly mixing, be configured as the spraying medicament containing weight ratio 25% ethanol, fill.
Usage and consumption are: in affected part external spraying, every day three times, at every turn every square centimeter spraying 3.5ml, bimester one course for the treatment of.
Embodiment 4
A kind of spraying medicament being used for the treatment of decubital ulcer of the present invention, the raw material containing Effective Component of Chinese Medicine forms and weight fraction is: Radix Dipsaci 32 grams, Sanguis Draxonis 5 grams, Adeps Bovis seu Bubali 30 grams, 18 grams, Radix Notoginseng, 16 grams, Flos Carthami, Semen Strychni (processed) 4 grams, succinum 6 grams, Herba Lycopi 20 grams, Lignum Sappan 12 grams, Aloe 3 grams, Herba Orostachyos 11 grams, Folium toxicodendri verniciflni 10 grams.
Be used for the treatment of a spraying medicament for decubital ulcer, preparation comprises following processing step:
(1) put in pot by fine sand, intense fire is fried to about 190 DEG C, adds clean Semen Strychni, stirs, and fries to heaving in brown, takes out, removes sand, cool to obtain Semen Strychni (processed), for subsequent use.
(2) take Sanguis Draxonis, Radix Notoginseng and succinum by raw material weight proportioning, remove impurity, mixing is broken, grinds to obtain fine powder, crosses 100 mesh sieves, for subsequent use.
(3) take step (1) gained Semen Strychni (processed) and Radix Dipsaci, Adeps Bovis seu Bubali, Flos Carthami, Herba Lycopi, Lignum Sappan, Aloe, Herba Orostachyos, Folium toxicodendri verniciflni by raw material weight proportioning, pulverize together, add the yellow wine of five times of weight, after boiling, continue immersion 2.3 hours, filter, get and boil liquid; In remaining medicinal residues, add the yellow wine of treble amount again, boil rear continuation immersion 2 hours, filter, get and boil liquid; Merge twice gained and boil liquid, filter, heating distillation and concentration to 3.8 times of crude drug weight, in raw material weight, take step (2) gained fine powder by proportioning, the heat slowly added after concentrating is boiled in liquid, stirs, soak 2.6 hours, again filter to get filtrate, for subsequent use.
(4) filtrate of step (3) gained is added ethanol, stirring and evenly mixing, be configured as the spraying medicament containing weight ratio 40% ethanol, fill.
Usage and consumption are: in affected part external spraying, every day three times, at every turn every square centimeter spraying 3ml, bimester one course for the treatment of.
For inspection curative effect of the present invention, choose 300 routine patients with bedsore, wherein the second stage of inflammatory infiltration phase Patients with Pressure Ulcers 176 example, three phase either shallow ulcerative stage Patients with Pressure Ulcers 124 examples.Wherein male 135 example, women 165 example, 36 ~ 77 years old age, 64 years old mean age.
Choice criteria: erythema blister and even ulcer appear in pressurized position, patient generates heat, poor appetite, and there is the visible pain of intuition person in affected part, and blood routine examination inflammatory parameters is abnormal.
Efficacy determination:
Remarkable: erythema vesicle goes down, skin incrustation and even recovery are normally, smooth without hyperplastic tissue; Blood routine examination is normal.
Alleviate: have percipient's pain relief; Skin ulcer face obtains part and controls, and area reduces; The part index numbers such as routine blood test granulocyte make moderate progress.
Invalid: clinical symptoms is without to be clearly better or decubital ulcer is festered and increased the weight of.
Patient uses Chinese medical spray medicament of the present invention to treat continuously, and after the course for the treatment of, observe the change of conditions of patients, therapeutic outcome is as follows:
Sum Significantly Alleviate Invalid Total effective rate
Data 300 100(33.3％) 192(64％) 8(2.7％) 91.9％
Below by concrete case, further checking is done to curative effect of medication provided by the invention.
Lee, man, 45 years old, because of traffic accident fracture of thoracic vertebrae, cause paraplegia, though stir through kith and kin after suffering from decubital ulcer, still develop into the second stage of inflammatory infiltration phase pressure ulcer, sacrococcygeal region 3cm × 5cm, has blister, peripheral oedema, brought into use medicine of the present invention to spray treatment, detumescence of forming a scab after two weeks, skin smooth after the course for the treatment of in 2010, cure, 60 days by a definite date.
Wang, female, 68 years old, because of cerebral infarction bed March, there is decubital ulcer in tail sacrum portion, after develop into the either shallow ulcerative stage pressure ulcer of three phases, visible 2cm × 3cm ulcer surface, has a small amount of secretions.After using the present invention to treat seven days, ooze out minimizing, pain relief, ulcer surface obviously closes up.After one course for the treatment of, wound surface heals substantially, and the red wound surface of residue 0.5cmx0.5cm size, continues by Drug therapy rehabilitation of the present invention.

Claims (3)

1. one kind is used for the treatment of the spraying medicament of decubital ulcer, it is characterized in that, the raw material containing Effective Component of Chinese Medicine forms and weight fraction is: Radix Dipsaci 16 ~ 32 parts, Sanguis Draxonis 4 ~ 6 parts, Adeps Bovis seu Bubali 30 ~ 52 parts, 6 ~ 18 parts, Radix Notoginseng, 8 ~ 20 parts, Flos Carthami, Semen Strychni (processed) 2 ~ 4 parts, succinum 6 ~ 12 parts, Herba Lycopi 12 ~ 20 parts, Lignum Sappan 12 ~ 20 parts, Aloe 3 ~ 8 parts, Herba Orostachyos 11 ~ 30 parts, Folium toxicodendri verniciflni 6 ~ 18 parts.
2. a kind of spraying medicament being used for the treatment of decubital ulcer according to claim 1, it is characterized in that, preferably, containing Effective Component of Chinese Medicine raw material composition and weight fraction be: Radix Dipsaci 24 parts, Sanguis Draxonis 5 parts, Adeps Bovis seu Bubali 40 parts, 12 parts, Radix Notoginseng, 14 parts, Flos Carthami, Semen Strychni (processed) 3 parts, succinum 9 parts, Herba Lycopi 16 parts, Lignum Sappan 16 parts, Aloe 6 parts, Herba Orostachyos 20 parts, Folium toxicodendri verniciflni 12 parts.
3. be used for the treatment of a spraying medicament preparation method for decubital ulcer, comprise following processing step:
(1) put in pot by fine sand, intense fire is fried to about 190 DEG C, adds clean Semen Strychni, stirs, and fries to heaving in brown, takes out, removes sand, cool to obtain Semen Strychni (processed), for subsequent use.
(2) take Sanguis Draxonis, Radix Notoginseng and succinum by raw material weight proportioning, remove impurity, mixing is broken, grinds to obtain fine powder, crosses 100 mesh sieves, for subsequent use.
(3) take step (1) gained Semen Strychni (processed) and Radix Dipsaci, Adeps Bovis seu Bubali, Flos Carthami, Herba Lycopi, Lignum Sappan, Aloe, Herba Orostachyos, Folium toxicodendri verniciflni by raw material weight proportioning, pulverize together, add the yellow wine of five times of weight, after boiling, continue immersion 2 ~ 3 hours, filter, get and boil liquid; In remaining medicinal residues, add the yellow wine of treble amount again, boil rear continuation immersion 1 ~ 2 hour, filter, get and boil liquid; Merge twice gained and boil liquid, filter, heating distillation and concentration to 3 ~ 4 times of crude drug weight, in raw material weight, take step (2) gained fine powder by proportioning, the heat slowly added after concentrating is boiled in liquid, stirs, soak 2 ~ 3 hours, again filter to get filtrate, for subsequent use.
(4) filtrate of step (3) gained is added medical alcohol, stirring and evenly mixing, be configured as the spraying medicament containing weight ratio 25 ~ 40% ethanol, fill.
CN201410747528.5A 2014-12-09 2014-12-09 A kind of spraying medicament for being used to treat bedsore Expired - Fee Related CN104491327B (en)

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CN101912517A (en) * 2009-08-17 2010-12-15 黄汉贤 Spray and gauze & ointment for preventing and curing bedsore and eczema
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