CN110292599A - A kind of burn, bedsore, chronic ulcer external preparation - Google Patents

A kind of burn, bedsore, chronic ulcer external preparation Download PDF

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Publication number
CN110292599A
CN110292599A CN201910753124.XA CN201910753124A CN110292599A CN 110292599 A CN110292599 A CN 110292599A CN 201910753124 A CN201910753124 A CN 201910753124A CN 110292599 A CN110292599 A CN 110292599A
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parts
skin
bedsore
drug
borneol
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萧正林
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Chongqing Zhengren Medical Devices Co Ltd
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Chongqing Zhengren Medical Devices Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37Digestive system
    • A61K35/413Gall bladder; Bile
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
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  • Alternative & Traditional Medicine (AREA)
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  • Medical Informatics (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Insects & Arthropods (AREA)
  • Organic Chemistry (AREA)
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  • Endocrinology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a kind of burns, the external preparation of bedsore, chronic ulcer, are made of the drug of following parts by weight: 100 parts of Radix Angelicae Sinensis, 100 parts of the coptis, 80 parts of garden burnet, 20 parts of polygonum cuspidate, 100 parts of rheum officinale, 100 parts of borneol, 60 parts of olive oil, 10 parts of honey, 10 parts of cow-bezoar, 10 parts of Moschus, 2000 parts of water.Prepare above-mentioned external drug method, comprising the following steps: weigh medicinal material by weight, water is added, heating is boiled, decocts;It filters off the dregs of a decoction and olive oil, borneol is added, dissolve borneol under stirring, and be uniformly mixed, bottle.It is of the invention it is a kind of treat because of burn, bedsore, chronic ulcer etc. caused by defect of skin external drug, drug used is cheap and easy to get, by the effective ingredient for extracting drug, a kind of manufactured biological agent, burn, bedsore, chronic ulcer etc. can be treated and cause defect of skin, without skin-grafting, patient can be mitigated because of bring high cost of making skin graft.Preparation method of the invention is simple, and medication is convenient.

Description

A kind of burn, bedsore, chronic ulcer external preparation
Technical field
The present invention relates to a kind of drug, in particular to a kind of burn, bedsore, chronic ulcer external preparation.
Background technique
Treatment such as burn, bedsore, chronic ulcer at present be easy to cause defect of skin, mainly by cutting after the treatment Scab skin-grafting (self skin-grafting and allo-skin graft), uses epidermal growth factor.But such method is at high cost, easy infection, to large area The self skin of defect is not able to satisfy, to before Heterosomata also among exploration.A kind of effective burn, bedsore, chronic ulcer are provided The problem of drug is those skilled in the art's urgent need to resolve.
Summary of the invention
The purpose of the present invention is to existing treatment since burn, bedsore, chronic ulcer etc. cause the outer of defect of skin Defect and deficiency existing for drug provide and a kind of treat burn, bedsore, the external drug of chronic ulcer and preparation method thereof.
For achieving the above object, the present invention adopts the following technical scheme: a kind of burn, bedsore, chronic ulcer it is outer With preparation, it is made of the drug of following parts by weight:
In drug used in the present invention:
Radix Angelicae Sinensis has effects that replenishing and activating blood, has antibacterial action to various bacteria.
The coptis has effects that purging intense heat, eliminating dampness, removing toxic substances, and contained effective component is to hemolytic streptococcus, the double balls of meningitis Bacterium, Diplococcus pneumopniae, comma bacillus, bacillus anthracis and staphylococcus aureus, shigella dysenteriae, Escherichia coli all have stronger Bacteriostasis.
Garden burnet has cooling blood and hemostasis, clearing heat and detoxicating effect.Effective component contained by it can stop blooding, to Staphylococcus aureus Bacterium, Escherichia coli, Pseudomonas aeruginosa have inhibiting effect.
Polygonum cuspidate has the function of wind-dispelling, dampness removing, broken silt, promoting menstruation.To staphylococcus aureus, micrococcus catarrhalis, B-mode hammer Bacterium, Escherichia coli, Pseudomonas aeruginosa have inhibiting effect.
Rheum officinale has the function of purge heat poison, broken stagnant, row extravasated blood.Have to staphylococcus aureus, shigella dysenteriae, streptococcus Inhibiting effect.
Borneol has the function of reducing swelling, relieves pain, lead to all keys, dissipate stagnated fire.The frigidoreceptor that part can be stimulated, has slight Local anaesthesia effect, can relieve pain and anti-corrosion.Borneol controls apoplexy lockjaw, pyreticosis coma , Jing Epilepsy phlegm confusing heart, deafness with qi stagnation, sore throat, mouth Sore, tympanitis, bitterly swollen, hemorrhoid, conjunctivitis, enterobiasis.1. inducing resuscitation of having one's ideas straightened out: being used for apoplexy, phlegm heat, coma key is closed, done auxiliary more Medicine.2. clearing away heat to and alleviating pain: it is kind to control red eye, swell pain, abscess of throat, pathopyretic ulcer and unhealing ulcer, ruptured abscess resistant to healing, it does not close up long.3. treating oral cavity to burst Ulcer, otitis media suppurative, bacterium property vaginitis, acute-chronic purulent tympanitis, surgical infection, apoplexy, convulsions, larynx x dentalgia, dispute It festers, scabies sore is itched, traumatic injury, blood stasis and swelling pain etc..For surgery, be conducive to affected part myogenic, analgesic, concentrate.
Contain the unsaturated fatty acid beneficial to human body in olive oil, and the ratio formed is appropriate, it is not easy to aoxidize.Especially It is to improve capillary circulation rich in can promote metabolism, bring the vitamin e of skin cell nutrition.Vitamin e can divide For α type, β type, γ type, δ type etc., and siritch is to belong to γ type.γ type vitamin e is that excellent polyphenoils mass-energy is effective Prevent and treat aging.Importantly, the oleic acid composition contained in siritch, which is also had by medicine confirmation, inhibits the diseases such as gastric ulcer, asthma Disease, prevention and treatment skin quality deterioration, improve the effect of immunity.For skin care maintenance, the contained ingredient of siritch is for wrinkle, black , there is the inhibiting effect to prevent trouble before it happens in the problems such as spot, dry skin.Therefore, other than edible, self-control beauty is done with siritch Hold anti-skin product, can also prevent skin aging.
Honey has bowl spares, moisturizes, and relieves pain, removing toxic substances;External application myogenic sore.For the empty pain of stomach duct and abdomen, dryness of the lung dry cough, intestinal dryness is just It is secret, solve Aconitum poisoning of drug;It controls sore outside and does not hold back, the effect of scald.
Cow-bezoar, which has, to clear away heart-fire, and slit phlegm is had one's ideas straightened out, cool liver, relieve the wind syndrome, removing toxic substances.For pyreticosis coma, stroke and phlegm confusing heart, twitch, The effect of epilepsy is gone mad, abscess of throat, aphthae, carbuncle swells furunculosis.
Moschus has inducing resuscitation of having one's ideas straightened out, blood circulation, swelling and pain relieving.For pyreticosis coma, apoplexy coma due to blocking of the respiratory system, bstruction of the circulation of vital energy is fainted cruelly, in Stupor is disliked, menostasis , Disorder lump in the abdomen, stillborn foetus of having difficult labour, chest impediment and cardialgia, trusted subordinate sudden and violent pain, the pain of injury caused by falling and tumbling, numbness pain is numb, carbuncle swells scrofula, and throat is swollen The effect of pain.
Prepare above-mentioned treatment burn, bedsore, the method for chronic ulcer external drug, comprising the following steps:
Step 1: it weighs: 10 parts of garden burnet;100 parts of Radix Angelicae Sinensis;100 parts of the coptis;70 parts of garden burnet;20 parts of polygonum cuspidate;100 parts of rheum officinale; 100 parts of borneol;60 parts of olive oil;10 parts of honey;10 parts of cow-bezoar;Moschus 10;2000 parts of water
Step 2: by garden burnet;Radix Angelicae Sinensis;The coptis;Garden burnet;Polygonum cuspidate;Rheum officinale;Olive oil;Honey;Cow-bezoar;Water is added in Moschus, adds Heat is boiled, decocts 70 minutes:
Step 3: the dregs of a decoction are filtered off.
Step 4: being added under olive oil, borneol, stirring dissolves borneol, and is uniformly mixed, bottling.Of the invention The case where drug is according to that cannot grow after human skin breakage, in conjunction with Chinese medicine characteristic, using scientific method, effective component extracting And a kind of manufactured biological agent makes defect skin growth with drug wrapping of the invention in human skin breakage, obtains full Meaning curative effect.
It is of the invention it is a kind of treat because of burn, bedsore, chronic ulcer caused by defect of skin external drug, Domestic medicinal valence Honest and clean to be easy to get, compatibility of drugs is scientific, reasonable, and by extracting the effective ingredient of drug, a kind of manufactured biological agent can treat burning Wound, bedsore, chronic ulcer etc. cause skin injury, do not have to skin-grafting, can mitigate patient because of bring high cost of making skin graft.This hair Bright preparation method is simple, and medication is convenient.
Specific embodiment
Below with reference to embodiment, invention is further described in detail.
Embodiment 1:
It weighs: 10 parts of garden burnet;100 parts of Radix Angelicae Sinensis;100 parts of the coptis;70 parts of garden burnet;20 parts of polygonum cuspidate;100 parts of rheum officinale;Borneol 100 Part;60 parts of olive oil;10 parts of honey;10 parts of cow-bezoar;Moschus 10;2000 parts of water is by garden burnet;Radix Angelicae Sinensis;The coptis;Garden burnet;Polygonum cuspidate;Greatly It is yellow;Olive oil;Honey;Cow-bezoar;Water is added in Moschus, and heating is boiled, decocts 70 minutes: filtering off the dregs of a decoction.Be added olive oil, borneol, Borneol is dissolved under stirring, and is uniformly mixed, is bottled.
Therapeutic effect of the invention by following Clinic Case it could be demonstrated that
1. Zhang, male, 41 years old, scalded after from the beginning upper leaching is lower on July 21st, 2003 by boiled water head, neck, chest, Abdomen, left upper extremity shoulder, right upper extremity shoulder, partial skin fall off.It can be seen that multiple bubbles that the surface of a wound differs in size, the gross area is about 26%, wherein deep 2 degree 10% or so, shallow 2 degree 12%, hurt latter hour given skin growth extract for treating 16 days to our hospital after whole Recovery from illness, does not stay scar.
2. pond so-and-so, male, 36 years old, because right hand forearm and neck are by gunpowder burns, skin coke X blacked on hand, and neck has more A bubble to differ in size, the gross area about 8%, 30 minutes after wound arrive the clear X of our hospital, using skin growth extract for treating, by 11 days After be completely recovered, non-scar.
3. Dong so-and-so, female, 78 years old, because suffer from cerebral thrombosis, senile dementia for a long time crouch cause skin of back fester, area about 5x7.5 Square centimeter, is supported through intravenous nutrition and anti-inflammatory treatment, external skin are fully recovered after growing extract for treating 38 days.
4. model so-and-so, male.67 years old, careless left foot back was scalded by copper water at work before 26 years, at once in Chongqing City the The treatment of five the People's Hospitals is reconnoitred without being clearly better, and secretion occurs repeatedly in patient's left foot surface of a wound, weight when symptom is light, through giving More than 90 days cure after skin growth extract for treating.
5. Hu, male, 56 years old, faint because epileptic seizure both hands are pressed on pressure cooker, when being found by household, both hands skin Skin is scalded into white, is very, partially in 3 degree of burns, to give skin growth hormone bandaging method for treating, while anti-inflammatory, fluid infusion with finger pulp And supportive treatment, it is completely recovered after 48 days, the left hand palm leaves a little scar, about 0.5x0.3cm size.
6. Zhang, male, 48 years old, because welded bridge reinforcing bar ignite accidentally gas tank injure neck, chest, abdomen and it is double on Limb causes neck, chest, skin of abdomen to fall off, and area about 11x21cm, double skin of upper extremity fall off, and area about 6x8cm gives skin After auxin and anti-inflammatory supportive treatment, fully recover within 13 days, non-scar.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one The widest scope of cause.

Claims (2)

1. the external preparation of a kind of burn, bedsore, chronic ulcer, it is characterised in that: be made of the Chinese medicine of following parts by weight:
2. the external preparation of a kind of burn according to claim 1, bedsore, chronic ulcer, special type are to include following Step:
Step 1: it weighs: 10 parts of garden burnet;100 parts of Radix Angelicae Sinensis;100 parts of the coptis;70 parts of garden burnet;20 parts of polygonum cuspidate;100 parts of rheum officinale;Borneol 100 parts;60 parts of olive oil;10 parts of honey;10 parts of cow-bezoar;Moschus 10;2000 parts of water
Step 2: by garden burnet;Radix Angelicae Sinensis;The coptis;Garden burnet;Polygonum cuspidate;Rheum officinale;Olive oil;Honey;Cow-bezoar;Water is added in Moschus, and heating is burnt It opens, decocts 70 minutes:
Step 3: the dregs of a decoction are filtered off.
Step 4: being added under olive oil, borneol, stirring dissolves borneol, and is uniformly mixed, bottling.
CN201910753124.XA 2019-08-15 2019-08-15 A kind of burn, bedsore, chronic ulcer external preparation Pending CN110292599A (en)

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Application Number Priority Date Filing Date Title
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1927292A (en) * 2006-09-05 2007-03-14 伍建华 External use drug for treating burn, bedsore, chronic ulcer and etc. and preparation method thereof
CN104666604A (en) * 2013-11-29 2015-06-03 烟台巨先药业有限公司 Ointment for burns and scalds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1927292A (en) * 2006-09-05 2007-03-14 伍建华 External use drug for treating burn, bedsore, chronic ulcer and etc. and preparation method thereof
CN104666604A (en) * 2013-11-29 2015-06-03 烟台巨先药业有限公司 Ointment for burns and scalds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
黄艳琴等: "45例大面积烫伤的中医治疗与护理 ", 《江西中医药》 *

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Application publication date: 20191001