CN109620915A - A kind of novel burn-scald medicine and preparation method thereof - Google Patents

A kind of novel burn-scald medicine and preparation method thereof Download PDF

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CN109620915A
CN109620915A CN201811581461.7A CN201811581461A CN109620915A CN 109620915 A CN109620915 A CN 109620915A CN 201811581461 A CN201811581461 A CN 201811581461A CN 109620915 A CN109620915 A CN 109620915A
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sesame oil
wax
scald
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杨晋
杨志
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

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Abstract

The invention belongs to technical field of Chinese medicine, and in particular to a kind of novel burn-scald medicine and preparation method thereof.A kind of novel burn-scald medicine, is made of raw material from the following weight: 500~700 parts of sesame oil, 90~100 parts of Guan Fen, 45~50 parts of Chinese wax, 45~55 parts of yellow lead, 35~45 parts of yellow wax, 20~30 parts of the bletilla striata, 25~35 parts of safflower, 10~15 parts of sedum lineare.The present invention has a moisturizing, heat-clearing toxin expelling, anti-inflammatory analgetic, more after the advantages of not staying scar.

Description

A kind of novel burn-scald medicine and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicine, and in particular to a kind of novel burn-scald medicine and preparation method thereof.
Background technique
Burn and scald is the histologic lesion due to caused by the factors such as heat, light, electricity, chemical substance and radioactive ray, pars affecta Mainly in skin and mucous membrane, serious person can injure subcutaneous tissue for position, such as muscle, bone, joint, or even injure internal organ, it is a kind of Complicated surgical disease.The severity of burn and scald can according to the weight of the position of burn and scald, size and burn and scald come Judgement, wherein burn and scald presses depth, is generally divided into three degree: I degree burn and scald: only injuring epidermis, injured rubefaction swells It is swollen, feel smartly pain, but appearance without blister.II degree of burn and scald: injuring skin corium, and part is red and swollen, generates heat, in great pain, There is obvious bubble.III degree burn and scald: full thickness skin includes that fat, bone and the muscle below skin all come to harm, and skin is burnt Black, downright bad, at this moment pain is not violent instead, because many nerves are also all damaged together.
Nowadays there is four problems, i.e. surface of a wound pain, necrosis progrediens, easy infection, scar in burn and scald therapeutic process The refractory conjunction of trace.The present invention develops one kind and has and well control using the dialectical opinion of tradition and modern scientific research achievement R. concomitans of Chinese medicine The novel burn-scald medicine of therapeutic effect, has great importance.
Summary of the invention
The purpose of the present invention is in view of the above deficiencies, providing a kind of novel burn-scald medicine and preparation method thereof, there is moisturizing, Heat-clearing toxin expelling, anti-inflammatory analgetic, more after the advantages of not staying scar.
The present invention is achieved through the following technical solutions:
A kind of novel burn-scald medicine, is made of raw material from the following weight: 500~700 parts of sesame oil, 90~100 parts of Guan Fen, white 45~50 parts of wax, 45~55 parts of yellow lead, 35~45 parts of yellow wax, 20~30 parts of the bletilla striata, 25~35 parts of safflower, sedum lineare 10~15 Part.
Preferably, it is made of raw material from the following weight: 600 parts of sesame oil, 95 parts of Guan Fen, 47 parts of Chinese wax, yellow It is 50 parts, 40 parts of yellow wax, 25 parts of the bletilla striata, 30 parts of safflower, 12 parts of sedum lineare red.
A kind of preparation method of novel burn-scald medicine, includes the following steps:
(1) sesame oil is taken, pours into pot and is heated to 200 DEG C~220 DEG C;
(2) Chinese wax and yellow lead are sequentially added into sesame oil, until oil bloom boil, yellow wax and pipe powder are then added, again to oil bloom After secondary boiling, the bletilla striata and safflower are sequentially added;
(3) finally sedum lineare is slowly added to, is heated to 180~220 DEG C, kept for 15~20 minutes, at this time all solids drug It mixes completely with sesame oil;
(4) 20~30 DEG C are cooled to, 80 meshes is crossed and isolates the dregs of a decoction, obtaining the thin viscous ointment of blackyellow is finished medicines.
Preferably, the oil bloom boiling is 180-200 DEG C.
The pharmacology analysis for each ingredient that the present invention uses:
Sesame oil can prevent tissue fat excessive oxidation rich in substances such as unsaturated fatty acid, vitamin Es, guarantee that cell is steady It is fixed, extend cell survival, there is the effect of solution taking poison and growing muscle due, moisturizing analgesic, grease is also contained in sesame oil, grease has logical intestines profit Just it acts on, the excretion of waste rubbish in body can be accelerated.
Guan Fen, cold in nature, acrid-sweet flavor.With disperse accumulation, the effect of desinsection, removing toxic substances, myogenic, infantile malnutrition due to digestive disturbances or intestinalparasites is controlled, diarrhea, abdominal pain due to enterositosis, Abdominal mass, malaria, scabies, ulcer, ulcer, aphtha, erysipelas, the illnesss such as scald.
Yellow wax, it is mild-natured, it is sweet in flavor.It is the natural secretion object of honeybee, after draining bee sugar by honeycomb, is boiled and obtained with water.Have The effect of solution taking poison and growing muscle due, stop dysentery hemostasis, analgesic therapy, inducing astrigency, sore, controls ulcer carbuncle on the back, and ulcer is to hold back, anxious pained, diarrhea purulence blood, long Rush down more than, vaginal bleeding with fetal movement, spermatorrhea, leukorrhagia.
Chinese wax, it is warm-natured, it is sweet in flavor, it is nontoxic.Esters containing macromolecule, alcohols therein are cerotin, 27 alcohol, 28 Alcohol, thirty alcohol;Acids is cerin, 27 acid, 28 acid, thirty acid and a small amount of palmitinic acid, stearic acid.With hemostasis, myogenic, The effect of analgesic therapy;Control metal-inflicted wound bleeding, hematuria, lower blood, sore burst for a long time and does not holds back, chancre.
Yellow lead, cold nature, acrid flavour.Externally applied toxicity removing and granulation promoting, takes desinsection orally, and preventing malaria is used for the more purulence of sore.Outside for powder and In plaster, there can be preferable removing toxic substances astriction with vegetable oil chemical combination for the bodying agent of plaster processed.
The bletilla striata, cold nature are bitter, sweet, puckery.With astringing to arrest bleeding, the effect of detumescence and promoting granulation, controls tuberculosis and omit blood, spit blood, nosebleed Blood, hematochezia, traumatic hemorrhage, ulcerative carbuncle pyogenic infections, scrofula, anal fistula, burn and scald, rhagadia manus et pedis, the illnesss such as anal fissure.
Safflower, acrid flavour are a kind of blood-activating and menstruation-regulating medicinals, have effects that blood circulation, removing blood stasis and acesodyne.Be mainly used for menostasis, The symptoms such as dysmenorrhea, lochia and abdominal mass lump in the abdomen, pained, traumatic injury uncomfortable in chest, are also used for various varication, nerve ending Inflammation, blood circulation are bad, lower limb numbness or livid purple equal congestions, contraindication in pregnancy.
Sedum lineare, it is cold in nature, it is sweet in flavor.With heat-clearing, the effect of detumescence, removing toxic substances, abscess of throat is controlled, carbuncle swells, furunculosis, erysipelas, Scald, snake bite, jaundice, the illnesss such as dysentery.
Beneficial effects of the present invention: the present invention chooses natural Chinese medicine, selects sesame oil, pipe powder solution taking poison and growing muscle due, and moisturizing stops It bitterly, is monarch drug in a prescription;Chinese wax, yellow lead, yellow wax, the bletilla striata, safflower astringing to arrest bleeding, removing blood stasis and acesodyne are altogether ministerial drug;Sedum lineare clearing heat for detumescence, Removing toxic substances analgesic is adjutant.All medicines share plays heat-clearing toxin expelling, anti-inflammatory analgetic altogether, and the function for saprophytic machine of dispelling integrates effect and treated, It is significant in efficacy.Present invention long-time service has no toxic side effect, and treatment cost is low, good effect, has moisturizing, heat-clearing toxin expelling, and anti-inflammatory stops Bitterly, more after the advantages of not staying scar.
Illustrate the curative effect of Chinese medicine of the present invention below by clinical data.
1, clinical observation
The present invention smears patient 90 of this drug by random selection, wherein male patient 52, and women 38.I degree, which is burnt, to scald Wound 44, II degree burn and scald 28 (deep II degree 14), III degree burn and scald 18.
2, treatment method
Application method: first carrying out cleaning and sterilizing to affected part with Iodophor, then appropriate Chinese medicine of the invention is taken to be applied to affected part, and daily 3 ~4 times, 0.5~1g, can fully recover for patients with mild 3~7 days every time, cure within moderate patient 10~20 days, severe patient 1~2 The moon is cured.
3, criterion of therapeutical effect
Significant: after smearing drug, symptom disappears, and scar disappears.
Effective: after smearing drug, symptom is substantially reduced, scar desalination.
Invalid: after smearing drug, symptom is not improved, and scar is unchanged.
4, efficacy result:
Treatment patient 90, wherein significant 83, effective 6, invalid 1, total effective rate 98.8%.
5, some cases data:
Case 1: Zhang, male, 40 years old, Heze City, Shandong Province He Lou people from town, switchgear box exploded in September, 2015 at work, burn Entire face, neck, ears, 10cm sections of arms on both hands palm and wrist joint, the condition of the injury are burnt up to deep II, the object that the same day is hospitalized The treatment of reason method, patient pain unbearably, can not fall asleep, and mouth can not open feed, maintain nutrition by degree thin rice gruel, gruel, weight is anxious Rapid decline, the condition of the injury is controlled after hospitalize a couple of days, but facial scar and incrustation are serious, and face is horrible, and both hands cannot be curved Song, after treated with medicament for treating scald of the invention, daily to affected part cleaning and sterilizing, ointment is applied to affected part, is burnt after 7 days Sclerderm takes off, and grows new skin again, and 14 Tian Hou faces, ears, the recovery of both hands skin is normal, continues to use this ointment one week, eye Eyelashes, eyebrow, beard are grown again, and skin smooth is as before, and incrustation disappears, and face is restored, and come back to work position.
Case 2: Liu, male, 30 years old, Heze City, Shandong Province tenant collected town peasant.In June, 2014 when repairing automobile, gasoline Accidental ignition, leads to neck, shoulder, left arm burn of palm in one's hands, and the condition of the injury is II degree burn and scald, the non-depigmentation of skin, but has many places Bubble, with medicinal ointment therapy of the present invention, continuous smear 7 days is fully recovered, and injury is without scar, no incrustation, and skin is smooth.
Case 3: Zhao so-and-so, female, 10 years old, Heze City people from Mudan District.In May, 2016 falls down when being at play by boiling water burn, It is scalded below neck to 50% area of thigh.The condition of the injury reaches II degree.To certain institute of traditional Chinese medicine's hospitalization 1 month, control disease still not yet in effect Feelings, trauma surface infestation, high fever.Upon somebody's introduction, begin to use this product to treat, recover from injury after 13 days, because using object when in hospital Reason means are treated and the time is longer, and wound incrustation hardening, there are a small amount of scars for skin.
Case 4: Chen, female, 38 years old, Heze high and new technology industrial development zone peasant.In September, 2017 is in mention when boiling water is gone upstairs falls accidentally , by boiling water burn face, chest, breast, the right hand and left leg during rolling down.The condition of the injury reaches II degree, sends treatment to hospital immediately.It is controlling The surface of a wound is torn during treatment, and infection aggravates, and in great pain, the state of an illness does not improve after a week.This month just leaves hospital, and begins to use this Then invention Chinese medicine starts to smear this product, that night pain subtracts, and patient is able to feel at ease to rest first to surface of a wound cleaning and sterilizing. Hereafter dressing is cleaned on time daily, application treatment, the surface of a wound is fully recovered after a week, and skin of face is smooth seamless, and new pore has been grown.Its The wound of remaining part position is also fully recovered after using this product January.
Case 5: Mr. Li, male 42 years old, removes and unloads work, people from Shanghai City.In April, 2016 is burnt by the concentrated sulfuric acid accidentally in unloading Wound, both hands palm are burnt, sharp ache.The condition of the injury reaches II degree, begins to use this product to treat upon somebody's introduction.The surface of a wound is first used cool Boiled water cleaning, hydrogen peroxide carries out disinfection, and then uses this ointment for treating scald, and same day pain is vertical to be subtracted, and when dressing burns downright bad skin Skin has fallen off, and wound is clearly better.It fully recovered after continuous use by one week.Both hands functional rehabilitation, skin smooth are flexible.
Case 6: Zhao so-and-so, male, 45 years old, Heze City small towns peasant.In August, 2016 is sprinkled by hot oil in trousers at home On, immediately fire wound.The condition of the injury reaches depth II degree.Firmly two breaches of 5 days wound dehiscence 10cm of certain hospital or so, and continuously outflow High protein yellow secretion, pain do not subtract.This doctor is gone to after being introduced to locate using present invention treatment.The treatment same day burns necrosis Skin fall off, secretion at second day breach disappears, and the new meat in third day is grown, and pain disappears after a week, can activity Freely.
Specific embodiment
Below by embodiment, the present invention is described in further detail.
Embodiment 1:
A kind of novel burn-scald medicine, is made of raw material from the following weight: 500 parts of sesame oil, 90 parts of Guan Fen, 45 parts of Chinese wax, yellow It is 45 parts, 35 parts of yellow wax, 20 parts of the bletilla striata, 25 parts of safflower, 10 parts of sedum lineare red.
A kind of preparation method of novel burn-scald medicine, includes the following steps:
(1) sesame oil is taken, pours into pot and is heated to 200 DEG C;
(2) Chinese wax and yellow lead are sequentially added into sesame oil, until oil bloom boil, yellow wax and pipe powder are then added, again to oil bloom After secondary boiling, the bletilla striata and safflower are sequentially added;
(3) finally sedum lineare is slowly added to, is heated to 180 DEG C, kept for 15 minutes, all solids drug and sesame oil are complete at this time It mixes entirely;
(4) 20 DEG C are cooled to, 80 meshes is crossed and isolates the dregs of a decoction, obtaining the thin viscous ointment of blackyellow is finished medicines.
The temperature of oil bloom boiling is 200 DEG C.
Application method: first carrying out cleaning and sterilizing to affected part with Iodophor, then appropriate Chinese medicine of the invention is taken to be applied to affected part, often It 3~4 times, 0.5~1g every time.
Embodiment 2: a kind of novel burn-scald medicine is made of raw material from the following weight: 700 parts of sesame oil, Guan Fen 100 Part, 50 parts of Chinese wax, 55 parts of yellow lead, 45 parts of yellow wax, 30 parts of the bletilla striata, 35 parts of safflower, 15 parts of sedum lineare.
A kind of preparation method of novel burn-scald medicine, includes the following steps:
(1) sesame oil is taken, pours into pot and is heated to 220 DEG C;
(2) Chinese wax and yellow lead are sequentially added into sesame oil, until oil bloom boil, yellow wax and pipe powder are then added, again to oil bloom After secondary boiling, the bletilla striata and safflower are sequentially added;
(3) finally sedum lineare is slowly added to, is heated to 220 DEG C, kept for 20 minutes, all solids drug and sesame oil are complete at this time It mixes entirely;
(4) 30 DEG C are cooled to, 80 meshes is crossed and isolates the dregs of a decoction, obtaining the thin viscous ointment of blackyellow is finished medicines.
The temperature of oil bloom boiling is 200 DEG C.
Application method: first carrying out cleaning and sterilizing to affected part with Iodophor, then appropriate Chinese medicine of the invention is taken to be applied to affected part, often It 3~4 times, 0.5~1g every time.
Embodiment 3:
A kind of novel burn-scald medicine, is made of raw material from the following weight: being made of raw material from the following weight: sesame oil 600 Part, 95 parts of Guan Fen, 47 parts of Chinese wax, 50 parts of yellow lead, 40 parts of yellow wax, 25 parts of the bletilla striata, 30 parts of safflower, 12 parts of sedum lineare.
A kind of preparation method of novel burn-scald medicine, includes the following steps:
(1) sesame oil is taken, pours into pot and is heated to 210 DEG C;
(2) Chinese wax and yellow lead are sequentially added into sesame oil, until oil bloom boil, yellow wax and pipe powder are then added, again to oil bloom After secondary boiling, the bletilla striata and safflower are sequentially added;
(3) finally sedum lineare is slowly added to, is heated to 200 DEG C, kept for 17 minutes, all solids drug and sesame oil are complete at this time It mixes entirely;
(4) 25 DEG C are cooled to, 80 meshes is crossed and isolates the dregs of a decoction, obtaining the thin viscous ointment of blackyellow is finished medicines.
The temperature of oil bloom boiling is 200 DEG C.
Application method: first carrying out cleaning and sterilizing to affected part with Iodophor, then appropriate Chinese medicine of the invention is taken to be applied to affected part, often It 3~4 times, 0.5~1g every time.

Claims (4)

1. a kind of novel burn-scald medicine, which is characterized in that be made of raw material from the following weight: 500~700 parts of sesame oil, pipe 90~100 parts of powder, 45~50 parts of Chinese wax, 45~55 parts of yellow lead, 35~45 parts of yellow wax, 20~30 parts of the bletilla striata, 25~35 parts of safflower, 10~15 parts of sedum lineare.
2. a kind of novel burn-scald medicine according to claim 1, which is characterized in that be made of raw material from the following weight: 600 parts of sesame oil, 95 parts of Guan Fen, 47 parts of Chinese wax, 50 parts of yellow lead, 40 parts of yellow wax, 25 parts of the bletilla striata, 30 parts of safflower, 12 parts of sedum lineare.
3. a kind of preparation method of novel burn-scald medicine according to claim 1 to 2, which is characterized in that including walking as follows It is rapid:
(1) sesame oil is taken, pours into pot and is heated to 200~220 DEG C;
(2) Chinese wax and yellow lead are sequentially added into sesame oil, until oil bloom boil, yellow wax and pipe powder are then added, again to oil bloom After secondary boiling, the bletilla striata and safflower are sequentially added;
(3) finally sedum lineare is slowly added to, is heated to 180~220 DEG C, kept for 15~20 minutes, at this time all solids drug It mixes completely with sesame oil;
(4) 20~30 DEG C are cooled to, 80 meshes is crossed and isolates the dregs of a decoction, obtaining the thin viscous ointment of blackyellow is finished medicines.
4. a kind of novel burn-scald medicine according to claim 3 and preparation method thereof, which is characterized in that the oil bloom boiling It is 180-200 DEG C.
CN201811581461.7A 2018-12-24 2018-12-24 A kind of novel burn-scald medicine and preparation method thereof Withdrawn CN109620915A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021044434A1 (en) * 2019-09-06 2021-03-11 Jose Huxley Composition for treatment of burn with scar removal

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021044434A1 (en) * 2019-09-06 2021-03-11 Jose Huxley Composition for treatment of burn with scar removal

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Application publication date: 20190416