CN104083421A - Traditional Chinese medicine ointment for treating bedsore and preparation method thereof - Google Patents

Traditional Chinese medicine ointment for treating bedsore and preparation method thereof Download PDF

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Publication number
CN104083421A
CN104083421A CN201410317529.6A CN201410317529A CN104083421A CN 104083421 A CN104083421 A CN 104083421A CN 201410317529 A CN201410317529 A CN 201410317529A CN 104083421 A CN104083421 A CN 104083421A
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parts
chinese medicine
traditional chinese
medicine ointment
treatment
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CN201410317529.6A
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Inventor
李春荣
刘翠萍
韩磊
朱慧
辛晓彤
张妮娜
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Affiliated Hospital of University of Qingdao
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Affiliated Hospital of University of Qingdao
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Abstract

The invention belongs to the field of traditional Chinese medicine and particularly relates to traditional Chinese medicine ointment for treating bedsore and a preparation method thereof. The traditional Chinese medicine ointment is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-15 parts of angelica root, 5-8 parts of frankincense, 2-3 parts of dahurian angelica root, 1-2 parts of red halloysite, 5-10 parts of old bletilla tuber, 3-5 parts of borneol, 15-20 parts of garden balsam stem, 10-15 parts of dry-land panax pseudo-ginseng, 80-120 parts of sesame oil and 150-200 parts of vaseline. The traditional Chinese medicine ointment for treating bedsore and the preparation method thereof have the advantages that the traditional Chinese medicines used meet the provisions of the pharmacopoeia of the People's Republic of China and are safe and reliable; all the medicines are harmonized, so that the traditional Chinese medicine ointment has the effects of promoting blood circulation to remove the necrotic tissue, detoxifying to ease pain and removing necrosis and promoting granulation and has the characteristics of definite treatment effect, high effect taking speed, high cure rate, no side effect and the like during the treatment of bedsore.

Description

Chinese medicine ointment for the treatment of decubital ulcer and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine ointment for the treatment of decubital ulcer and preparation method thereof.
Background technology
Decubital ulcer another name " pressure ulcer ", " pressure ulcer ".Decubital ulcer is the long-term pressurized of body part, makes blood circulation be subject to obstacle, causes that skin and subcutaneous tissue vesicle, ulcer or gangrene occur because of ischemia.Generally speaking, decubital ulcer is because nutrition blood is for the result in latter stage with body tissue generation circulatory disorders.
How due to illness decubital ulcer paralysis, and long-term bed is had bad physiques, and it is improper to nurse, and stands up the patient Yi Fasheng of movable inconvenience and limbs sensory disturbance.Excessively become thin, obesity, edema, arteriosclerosis all easily impels decubital ulcer to form.There is redness and blister in the early stage visible local skin of patient, becomes aubergine later and start ulceration, and ulceration primary sore face is scarlet transudate, and then skin ulcer face is deepened, colour-darkening blackout.Be apt to occur in the receptor weight such as back, sacrum tail, hip joint, heel and external malleolus and compel place.According to related documents report, approximately there are every year 60000 people to die from decubital ulcer complication.According to the evolution of decubital ulcer, light and heavy degree is different, can be divided into next issues of: first phase, the non-fading limitation erythema that occurs pressure at bone knuckle place skin, but skin complete, dark skin may not have obvious pale change, but its color may be different with skin around.Second phase, the disappearance of part dermis thickness is rendered as a shallow open ulcer, and has a peach damage location, and inorganization comes off, and also can present a congested vesicle complete or that open/break.Three phases, holostrome wound loses holostrome skin histology, and except bone tendon or not yet exposure place of muscle, visible subcutaneous tissue, have slough to come off, but the degree of depth of slough is not too clear and definite, may move under water and sinus tract.The fourth phase, loses holostrome skin histology, and companion's bone, tendon or muscle expose, and part can occur that slough comes off or eschar, moves under water, sinus tract.By stages the stage, holostrome wound, loses holostrome skin histology, and the bottom rot of ulcer (yellow, yellowish-brown, Lycoperdon polymorphum Vitt, green, brown) and (or) crust (yellowish-brown and darkish complexion color) cover.Only have eschar or crust fully to remove, could determine the real degree of depth and by stages.
Clinical treatment is mainly that anti-inflammation is main at present, prevent secondary infection, but this class medicine has stronger zest to wound surface, easy damaged new granulation tissue while changing dressings, be unfavorable for the healing of wound surface, the therefore granulation promoting open sore part that heals rapidly, so clinical efficacy is unsatisfactory.So far, there is no comparatively desirable medicine and method both at home and abroad.
Summary of the invention
According to above the deficiencies in the prior art, the invention provides a kind of Chinese medicine ointment for the treatment of decubital ulcer and preparation method thereof, it is evident in efficacy, safe and reliable, have no side effect, and has wide potential applicability in clinical practice.
A kind of Chinese medicine ointment for the treatment of decubital ulcer of the present invention, according to parts by weight meter, by following raw material of Chinese medicine, be prepared from: 150~200 parts, 10~15 parts of Radix Angelicae Sinensis, 5~8 parts of Olibanums, 2~3 parts of the Radixs Angelicae Dahuricae, 1~2 part of red blood fat, 5~10 parts of old splendid achnatherums, 3~5 parts of Borneolum Syntheticums, 15~20 parts of Herba speranskiae tuberculataes, 10~15 parts of Radix Notoginsengs, 80~120 parts, Oleum Sesami and vaseline.
Preferred version is as follows:
According to parts by weight meter, by following raw material of Chinese medicine, be prepared from: 180 parts, 10 parts of Radix Angelicae Sinensis, 5 parts of Olibanums, 3 parts of the Radixs Angelicae Dahuricae, 1 part of red blood fat, 10 parts of old splendid achnatherums, 5 parts of Borneolum Syntheticums, 20 parts of Herba speranskiae tuberculataes, 10 parts of Radix Notoginsengs, 100 parts, Oleum Sesami and vaseline.
The preparation method of the Chinese medicine ointment for the treatment of decubital ulcer of the present invention, according to following steps, carry out:
(1) Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, red blood fat, old splendid achnatherum, Herba speranskiae tuberculatae and Radix Notoginseng are put into Oleum Sesami and soak 22~28h;
(2) after soaking, boil with high heat 45~90min;
(3) naturally cool to room temperature after removing slag, place 22~28h, then add the vaseline 30~60min that simmers in water to it;
(4) naturally cool to room temperature, then add the Borneolum Syntheticum 20~40min that simmers in water;
(5) naturally cool to room temperature, after autoclave sterilization, the Chinese medicine ointment of the decubital ulcer that can obtain medical treatment.
Preferably according to following steps, carry out:
(1) Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, red blood fat, old splendid achnatherum, Herba speranskiae tuberculatae and Radix Notoginseng are put into Oleum Sesami and soak 24h;
(2) after soaking, boil with high heat 60min;
(3) naturally cool to room temperature after removing slag, place 24h, then add the vaseline 40min that simmers in water to it;
(4) naturally cool to room temperature, then add the Borneolum Syntheticum 30min that simmers in water;
(5) naturally cool to room temperature, after autoclave sterilization, the Chinese medicine ointment of the decubital ulcer that can obtain medical treatment.
During use, first use normal saline sterile perimeter skin, the Chinese medicine ointment for the treatment of decubital ulcer prepared by the present invention is applied in affected part, and change dressings once every day.
Pharmacology analysis:
Radix Angelicae Sinensis: acrid in the mouth is warm in nature, enriches blood, blood circulation and removing stasis, the function of tissue regeneration promoting blood.
Olibanum: acrid in the mouth is covered with mat warm in nature, has blood circulation promoting regulates qi, and pain relieving granulation promoting can be controlled swollen ulcer drug, all skin ulcers, the effect that blood stasis is had a pain.
The Radix Angelicae Dahuricae: acrid in the mouth is warm in nature, can control skin ailment said due to cold or exposure noxious dampness associated diseases, has the effect of the evacuation of pus of invigorating blood circulation, and is again the outer main medicine of disease of surgery skin sore.
Halloysitum Rubrum: the acid temperature of sweet in the mouth, after being adapted to ulcer sores and wearing out, that does not close up for a long time carrys out external application with it, can play the effect of promoting tissue regeneration and ulcer healing.
Old splendid achnatherum: bitter in the mouth is flat, has astringing to arrest bleeding, and the effect of muscle-growing and detumescence, can control the diseases such as swollen ulcer drug, skin infection, and carbuncle is controlled in external application, water becomes pus can make it to dissipate, and the made it promoting tissue regeneration and wound healing of having burst, is the main good medicine of surgical diseases.
Borneolum Syntheticum: acrid in the mouth is bitter, cold nature, QI exhaustion fragrance, energy waking up the patient from unconsciousness by clearing away heat, ulcer sores curative effect is all good.
Herba speranskiae tuberculatae: pungent, temperature.Return Liver Channel.Expelling wind and removing dampness, promoting blood circulation and detumescence pain relieving.For rheumatic arthralgia, muscles contracture, traumatic injury, sore swollen toxin.The sweet peaceful blue or green Chinese herbal medicine in < < Shan selects > > to use these product, controls eczema scrotum, sore swollen toxin.Therefore can think Herba speranskiae tuberculatae treatment skin ulcer tinea toxic swelling, eczema scrotum, general many decoction being used as a lotion.Because this medicine washout also has priming, penetrate meridians, blood vessels, and dispel the wind, invigorate blood circulation, the feature of pain relieving.
Radix Notoginseng: herb is medicinal, hemostasis, pain relieving, dissipating blood stasis for subsidence of swelling; Water is got or the clothes of steeping in wine are controlled various hemorrhage; Fresh goods is taken off rotten external application furuncle carbuncle.Cure mainly dissipating blood stasis hemostasis, the analgesia of calming the nerves.For thrombocytopenic purpura, epistaxis, spit blood, spitting of blood, gingival hemorrhage, digestive tract hemorrhage, metrorrhagia, cardiopalmus, irritated insomnia; Traumatic injury is controlled in external, traumatic hemorrhage, burn and scald.
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases and have the effect of promoting blood circulation and eliminating necrosis, removing toxic substances analgesia, removing the necrotic tissue and promoting granulation, treatment decubital ulcer has that determined curative effect, instant effect, cure rate are high, the feature such as have no side effect.
Curative effect judgement:
Curative effect determinate standard: (1) recovery from illness: ulcer forms a scab and comes off, and local organization is repaired completely.(2) take a turn for the better: ulcer area is dwindled, granulation tissue well-grown, wound surface recovery from illness reaches more than 50%.(3) invalid: granulation tissue undergrowth, wound surface is without healing sign.
Select the routine clinical observation of I inpatient of institute 128, male 68 examples, female's 60 examples; 9~72 years old age, mean age, 38.6 years old; Decubital ulcer position: sacrococcygeal region 86 examples, back 29 examples, heel portion 13 examples; Decubital ulcer area: the maximum 12.3cm of diameter, minimum 5.7cm.The most shallow to subcutis, the most deeply see the local exposure of rumpbone or calcaneus.Patient, with normal saline sterilization decubital ulcer place, being then applied in to affected part by Chinese medicinal ointment with cotton swab, then with gauze, ointment being covered, in order to avoid make dirty clothes or bedding are coated with 1 every day, 5 days is a course for the treatment of.
Therapeutic outcome: after two course of therapy, recovery from illness 89 examples, 36 examples that take a turn for the better, invalid 3 examples, total effective rate reaches 97.7%.
Below enumerate several model cases:
Wei, man, 62 years old, retired worker.4 years prolapse carbuncle in the occipital region hemorrhages, though through rescuing Survive the perils of life, leave sequela and be paralyzed in bed, can't take care of oneself at all, ill later six months, found decubital ulcer, begin treatment immediately, but therapeutic effect is not obvious, and the wound surface scope of heel parts and buttocks expands gradually, hurt like hell, is used Chinese medicinal ointment of the present invention after 2 days, and pain symptom obviously alleviates, wound surface grows new granulation and starts and occurs healing, after two courses for the treatment of, fully recovers.
Ma, man, 35 years old, builder.When work in building site, industrial accident occurs, cause and fracture the right legs, with Gypsum Fibrosum, fix, find that erythema decubitus symptom appears in right inboard leg while removing Gypsum Fibrosum after 20 days, with normal saline sterilization, smear Chinese medicinal ointment of the present invention immediately, connect and be coated with 3 days, decubitus symptom disappears.
The specific embodiment
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1:
A kind of Chinese medicine ointment for the treatment of decubital ulcer, according to parts by weight meter, by following raw material of Chinese medicine, be prepared from: 180 parts, 10 parts of Radix Angelicae Sinensis, 5 parts of Olibanums, 3 parts of the Radixs Angelicae Dahuricae, 1 part of red blood fat, 10 parts of old splendid achnatherums, 5 parts of Borneolum Syntheticums, 20 parts of Herba speranskiae tuberculataes, 10 parts of Radix Notoginsengs, 100 parts, Oleum Sesami and vaseline.
Embodiment 2:
According to the formula of embodiment 1, the Chinese medicine ointment of preparation treatment decubital ulcer, according to following steps, carry out:
(1) Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, red blood fat, old splendid achnatherum, Herba speranskiae tuberculatae and Radix Notoginseng are put into Oleum Sesami and soak 24h;
(2) after soaking, boil with high heat 60min;
(3) naturally cool to room temperature after removing slag, place 24h, then add the vaseline 40min that simmers in water to it;
(4) naturally cool to room temperature, then add the Borneolum Syntheticum 30min that simmers in water;
(5) naturally cool to room temperature, after autoclave sterilization, the Chinese medicine ointment of the decubital ulcer that can obtain medical treatment.
During use, with normal saline sterilization decubital ulcer place, the Chinese medicine ointment for the treatment of decubital ulcer prepared by the present invention is applied in affected part, and change dressings once every day.

Claims (4)

1. a Chinese medicine ointment for the treatment of decubital ulcer, it is characterized in that, according to parts by weight meter, by following raw material of Chinese medicine, being prepared from: 150~200 parts, 10~15 parts of Radix Angelicae Sinensis, 5~8 parts of Olibanums, 2~3 parts of the Radixs Angelicae Dahuricae, 1~2 part of red blood fat, 5~10 parts of old splendid achnatherums, 3~5 parts of Borneolum Syntheticums, 15~20 parts of Herba speranskiae tuberculataes, 10~15 parts of Radix Notoginsengs, 80~120 parts, Oleum Sesami and vaseline.
2. the Chinese medicine ointment for the treatment of decubital ulcer according to claim 1, it is characterized in that, according to parts by weight meter, by following raw material of Chinese medicine, being prepared from: 180 parts, 10 parts of Radix Angelicae Sinensis, 5 parts of Olibanums, 3 parts of the Radixs Angelicae Dahuricae, 1 part of red blood fat, 10 parts of old splendid achnatherums, 5 parts of Borneolum Syntheticums, 20 parts of Herba speranskiae tuberculataes, 10 parts of Radix Notoginsengs, 100 parts, Oleum Sesami and vaseline.
3. a preparation method for the Chinese medicine ointment for the treatment of decubital ulcer claimed in claim 1, is characterized in that carrying out according to following steps:
(1) Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, red blood fat, old splendid achnatherum, Herba speranskiae tuberculatae and Radix Notoginseng are put into Oleum Sesami and soak 22~28h;
(2) after soaking, boil with high heat 45~90min;
(3) naturally cool to room temperature after removing slag, place 22~28h, then add the vaseline 30~60min that simmers in water to it;
(4) naturally cool to room temperature, then add the Borneolum Syntheticum 20~40min that simmers in water;
(5) naturally cool to room temperature, after autoclave sterilization, the Chinese medicine ointment of the decubital ulcer that can obtain medical treatment.
4. the preparation method of the Chinese medicine ointment for the treatment of decubital ulcer according to claim 3, is characterized in that carrying out according to following steps:
(1) Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, red blood fat, old splendid achnatherum, Herba speranskiae tuberculatae and Radix Notoginseng are put into Oleum Sesami and soak 24h;
(2) after soaking, boil with high heat 60min;
(3) naturally cool to room temperature after removing slag, place 24h, then add the vaseline 40min that simmers in water to it;
(4) naturally cool to room temperature, then add the Borneolum Syntheticum 30min that simmers in water;
(5) naturally cool to room temperature, after autoclave sterilization, the Chinese medicine ointment of the decubital ulcer that can obtain medical treatment.
CN201410317529.6A 2014-07-04 2014-07-04 Traditional Chinese medicine ointment for treating bedsore and preparation method thereof Pending CN104083421A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104491412A (en) * 2014-12-26 2015-04-08 齐方梅 Traditional Chinese medicine unguent for treating bedsore and preparation method thereof
CN109453228A (en) * 2019-01-07 2019-03-12 刘春生 A kind of Chinese medicine composition for treating bedsore and diabetic complication

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Publication number Priority date Publication date Assignee Title
CN1548139A (en) * 2003-05-19 2004-11-24 魏茂武 Bedsore ointment and its prepn process
US7740886B1 (en) * 2008-07-11 2010-06-22 Sara Vargas Bedsore treatment ointment
CN102366544A (en) * 2011-08-20 2012-03-07 钱家美 Bedsore ointment and preparation method thereof

Patent Citations (3)

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CN1548139A (en) * 2003-05-19 2004-11-24 魏茂武 Bedsore ointment and its prepn process
US7740886B1 (en) * 2008-07-11 2010-06-22 Sara Vargas Bedsore treatment ointment
CN102366544A (en) * 2011-08-20 2012-03-07 钱家美 Bedsore ointment and preparation method thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104491412A (en) * 2014-12-26 2015-04-08 齐方梅 Traditional Chinese medicine unguent for treating bedsore and preparation method thereof
CN109453228A (en) * 2019-01-07 2019-03-12 刘春生 A kind of Chinese medicine composition for treating bedsore and diabetic complication

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Application publication date: 20141008