CN104056066A - Traditional Chinese medicine unguent for treating bedsores and preparation method of traditional Chinese medicine unguent for treating bedsores - Google Patents

Traditional Chinese medicine unguent for treating bedsores and preparation method of traditional Chinese medicine unguent for treating bedsores Download PDF

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Publication number
CN104056066A
CN104056066A CN201410317707.5A CN201410317707A CN104056066A CN 104056066 A CN104056066 A CN 104056066A CN 201410317707 A CN201410317707 A CN 201410317707A CN 104056066 A CN104056066 A CN 104056066A
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parts
chinese medicine
traditional chinese
decubital ulcer
room temperature
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CN201410317707.5A
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Inventor
李春荣
刘翠萍
韩磊
朱慧
辛晓彤
张妮娜
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Affiliated Hospital of University of Qingdao
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Affiliated Hospital of University of Qingdao
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Abstract

The invention belongs to the field of traditional Chinese medicine, and particularly relates to traditional Chinese medicine unguent for treating bedsores and a preparation method of the traditional Chinese medicine unguent for treating the bedsores. The traditional Chinese medicine unguent comprises, by weight, 10-15 parts of angelica sinensis, 5-8 parts of frankincense, 2-3 parts of radix angelicae, 1-2 parts of red serum lipid, 5-10 parts of Chinese elder herbs, 3-5 parts of borneol, 10-15 parts of coptis chinensis, 5-10 parts of scutellaria baicalensis, 1-2 parts of alums, 80-120 parts of sesame oil and 150-200 parts of Vaseline. The traditional Chinese medicine unguent has the advantages that the adopted traditional Chinese medicine meets rules in the pharmacopoeia of the People's Republic of China and is safe and reliable. All kinds of traditional Chinese medicines are in proper proportion and have the effects of invigorating the circulation of blood, removing necrotic tissues, conducting detoxication, easing pains and promoting granulation. The traditional Chinese medicine unguent has the advantages of being exact in curative effect, high in effect taking speed and curing rate, free of side effects and the like when the bedsores are treated.

Description

A kind of Chinese medicine ointment for the treatment of decubital ulcer and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine ointment for the treatment of decubital ulcer and preparation method thereof.
Background technology
Decubital ulcer another name " pressure ulcer ", " pressure ulcer ".Decubital ulcer is the long-term pressurized of body part, makes blood circulation be subject to obstacle, causes that skin and subcutaneous tissue vesicle, ulcer or gangrene occur because of ischemia.Generally speaking, decubital ulcer is because nutrition blood is for the result in latter stage with body tissue generation circulatory disorders.
How due to illness decubital ulcer paralysis, and long-term bed is had bad physiques, and it is improper to nurse, and stands up the patient Yi Fasheng of movable inconvenience and limbs sensory disturbance.Excessively become thin, obesity, edema, arteriosclerosis all easily impels decubital ulcer to form.There is redness and blister in the early stage visible local skin of patient, becomes aubergine later and start ulceration, and ulceration primary sore face is scarlet transudate, and then skin ulcer face is deepened, colour-darkening blackout.Be apt to occur in the receptor weight such as back, sacrum tail, hip joint, heel and external malleolus and compel place.According to related documents report, approximately there are every year 60000 people to die from decubital ulcer complication.According to the evolution of decubital ulcer, light and heavy degree is different, can be divided into next issues of: first phase, the non-fading limitation erythema that occurs pressure at bone knuckle place skin, but skin complete, dark skin may not have obvious pale change, but its color may be different with skin around.Second phase, the disappearance of part dermis thickness is rendered as a shallow open ulcer, and has a peach damage location, and inorganization comes off, and also can present a congested vesicle complete or that open/break.Three phases, holostrome wound loses holostrome skin histology, and except bone tendon or not yet exposure place of muscle, visible subcutaneous tissue, have slough to come off, but the degree of depth of slough is not too clear and definite, may move under water and sinus tract.The fourth phase, loses holostrome skin histology, and companion's bone, tendon or muscle expose, and part can occur that slough comes off or eschar, moves under water, sinus tract.By stages the stage, holostrome wound, loses holostrome skin histology, and the bottom rot of ulcer (yellow, yellowish-brown, Lycoperdon polymorphum Vitt, green, brown) and (or) crust (yellowish-brown and black) cover.Only have eschar or crust fully to remove, could determine the real degree of depth and by stages.
Clinical treatment is mainly that anti-inflammation is main at present, prevent secondary infection, but this class medicine has stronger zest to wound surface, easy damaged new granulation tissue while changing dressings, be unfavorable for the healing of wound surface, the therefore granulation promoting open sore part that heals rapidly, so clinical efficacy is unsatisfactory.So far, there is no comparatively desirable medicine and method both at home and abroad.
Summary of the invention
According to above the deficiencies in the prior art, the invention provides a kind of Chinese medicine ointment for the treatment of decubital ulcer and preparation method thereof, it is evident in efficacy, safe and reliable, have no side effect, and has wide potential applicability in clinical practice.
A kind of Chinese medicine ointment for the treatment of decubital ulcer of the present invention, according to parts by weight meter, by following raw material of Chinese medicine, be prepared from: 150~200 parts, 10~15 parts of Radix Angelicae Sinensis, 5~8 parts of Olibanums, 2~3 parts of the Radixs Angelicae Dahuricae, 1~2 part of red blood fat, 5~10 parts of old splendid achnatherums, 3~5 parts of Borneolum Syntheticums, 10~15 parts of Rhizoma Coptidis, 5~10 parts of Radix Scutellariaes, 1~2 part, Alumen, 80~120 parts, Oleum Sesami and vaseline.
Preferred version is as follows:
According to parts by weight meter, by following raw material of Chinese medicine, be prepared from: 180 parts, 10 parts of Radix Angelicae Sinensis, 5 parts of Olibanums, 3 parts of the Radixs Angelicae Dahuricae, 1 part of red blood fat, 10 parts of old splendid achnatherums, 5 parts of Borneolum Syntheticums, 15 parts of Rhizoma Coptidis, 10 parts of Radix Scutellariaes, 1 part, Alumen, 100 parts, Oleum Sesami and vaseline.
The preparation method of the Chinese medicine ointment for the treatment of decubital ulcer of the present invention, according to following steps, carry out:
(1) Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, red blood fat, old splendid achnatherum, Rhizoma Coptidis, Radix Scutellariae and Alumen are put into Oleum Sesami and soak 22~28h;
(2) after soaking, boil with high heat 45~90min;
(3) naturally cool to room temperature after removing slag, place 22~28h, then add the vaseline 30~60min that simmers in water to it;
(4) naturally cool to room temperature, then add the Borneolum Syntheticum 20~40min that simmers in water;
(5) naturally cool to room temperature, after autoclave sterilization, the Chinese medicine ointment of the decubital ulcer that can obtain medical treatment.
Preferably according to following steps, carry out:
(1) Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, red blood fat, old splendid achnatherum, Rhizoma Coptidis, Radix Scutellariae and Alumen are put into Oleum Sesami and soak 24h;
(2) after soaking, boil with high heat 60min;
(3) naturally cool to room temperature after removing slag, place 24h, then add the vaseline 40min that simmers in water to it;
(4) naturally cool to room temperature, then add the Borneolum Syntheticum 30min that simmers in water;
(5) naturally cool to room temperature, after autoclave sterilization, the Chinese medicine ointment of the decubital ulcer that can obtain medical treatment.
During use, first use normal saline sterile perimeter skin, the Chinese medicine ointment for the treatment of decubital ulcer prepared by the present invention is applied in affected part, and change dressings once every day.
Pharmacology analysis:
Radix Angelicae Sinensis: acrid in the mouth is warm in nature, enriches blood, blood circulation and removing stasis, the function of tissue regeneration promoting blood.
Olibanum: acrid in the mouth is covered with mat warm in nature, has blood circulation promoting regulates qi, and pain relieving granulation promoting can be controlled swollen ulcer drug, all skin ulcers, the effect that blood stasis is had a pain.
The Radix Angelicae Dahuricae: acrid in the mouth is warm in nature, can control skin ailment said due to cold or exposure noxious dampness associated diseases, has the effect of the evacuation of pus of invigorating blood circulation, and is again the outer main medicine of disease of surgery skin sore.
Halloysitum Rubrum: the acid temperature of sweet in the mouth, after being adapted to ulcer sores and wearing out, that does not close up for a long time carrys out external application with it, can play the effect of promoting tissue regeneration and ulcer healing.
Old splendid achnatherum: bitter in the mouth is flat, has astringing to arrest bleeding, and the effect of muscle-growing and detumescence, can control the diseases such as swollen ulcer drug, skin infection, and carbuncle is controlled in external application, water becomes pus can make it to dissipate, and the made it promoting tissue regeneration and wound healing of having burst, is the main good medicine of surgical diseases.
Borneolum Syntheticum: acrid in the mouth is bitter, cold nature, QI exhaustion fragrance, energy waking up the patient from unconsciousness by clearing away heat, ulcer sores curative effect is all good.
Rhizoma Coptidis: for heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.The kind clear part of the body cavity above the diaphragm housing the heart and lungs of Rhizoma Coptidis (processed with wine) is burning hot.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.For cold and heat, tie mutually damp and hot middle resistance, feeling of fullness vomiting.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
Radix Scutellariae: root is used as medicine, bitter in the mouth, cold in nature, can heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.
Alumen: Alumen sour-puckery flavor cold in nature, has stronger astriction.The traditional Chinese medical science thinks, Alumen has removing toxic substances parasite killing, quick-fried wet antipruritic, hemostasis antidiarrheal, the effects such as the anti-trichomonas vaginitis of effect of heat clearing away expectorant.
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases and have the effect of promoting blood circulation and eliminating necrosis, removing toxic substances analgesia, removing the necrotic tissue and promoting granulation, treatment decubital ulcer has that determined curative effect, instant effect, cure rate are high, the feature such as have no side effect.
Curative effect judgement:
Curative effect determinate standard: (1) recovery from illness: ulcer forms a scab and comes off, and local organization is repaired completely.(2) take a turn for the better: ulcer area is dwindled, granulation tissue well-grown, wound surface recovery from illness reaches more than 50%.(3) invalid: granulation tissue undergrowth, wound surface is without healing sign.
Select the routine clinical observation of I inpatient of institute 100, male 60 examples, female's 40 examples; 9~72 years old age, 42 years old mean age; Decubital ulcer position: sacrococcygeal region 64 examples, back 25 examples, heel portion 11 examples; Decubital ulcer area: the maximum 12.3cm of diameter, minimum 5.7cm.The most shallow to subcutis, the most deeply see the local exposure of rumpbone or calcaneus.Patient, with normal saline sterilization decubital ulcer place, being then applied in to affected part by Chinese medicinal ointment with cotton swab, then with gauze, ointment being covered, in order to avoid make dirty clothes or bedding are coated with 1 every day, 5 days is a course for the treatment of.
Therapeutic outcome: after two course of therapy, recovery from illness 92 examples, 6 examples that take a turn for the better, invalid 2 examples, total effective rate reaches 98%.
Below enumerate several model cases:
Pueraria lobota, female, 43 years old, the employee of public institution.Because vehicle accident occurs, brain injury stupor, in the while in hospital, there is erythema lump in back and shank, is diagnosed as decubital ulcer, smears immediately Chinese medicinal ointment of the present invention, smears continuously 3 days, transference cure, revives after 20 days in hospital, until be discharged from hospitals upon recovery, does not occur decubitus symptom.
Lin, man, 59 years old, peasant.Due to illness long-term bed, because skin is oppressed for a long time, skin can not get the normal keeping of blood, and decubital ulcer appears in patient's sacrococcygeal region, skin ulceration, wound surface is darker, and slough covers, adularescent exudate, the taste giving out a foul smell, use Chinese medicinal ointment of the present invention to smear after two courses for the treatment of, wound healing, patient skin does not leave any sequela.
The specific embodiment
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1:
A kind of Chinese medicine ointment for the treatment of decubital ulcer, according to parts by weight meter, by following raw material of Chinese medicine, be prepared from: 180 parts, 10 parts of Radix Angelicae Sinensis, 5 parts of Olibanums, 3 parts of the Radixs Angelicae Dahuricae, 1 part of red blood fat, 10 parts of old splendid achnatherums, 5 parts of Borneolum Syntheticums, 15 parts of Rhizoma Coptidis, 10 parts of Radix Scutellariaes, 1 part, Alumen, 100 parts, Oleum Sesami and vaseline.
Embodiment 2:
According to the formula of embodiment 1, the Chinese medicine ointment of preparation treatment decubital ulcer, according to following steps, carry out:
(1) Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, red blood fat, old splendid achnatherum, Rhizoma Coptidis, Radix Scutellariae and Alumen are put into Oleum Sesami and soak 24h;
(2) after soaking, boil with high heat 60min;
(3) naturally cool to room temperature after removing slag, place 24h, then add the vaseline 40min that simmers in water to it;
(4) naturally cool to room temperature, then add the Borneolum Syntheticum 30min that simmers in water;
(5) naturally cool to room temperature, after autoclave sterilization, the Chinese medicine ointment of the decubital ulcer that can obtain medical treatment.
During use, with normal saline sterilization decubital ulcer place, the Chinese medicine ointment for the treatment of decubital ulcer prepared by the present invention is applied in affected part, and change dressings once every day.

Claims (4)

1. a Chinese medicine ointment for the treatment of decubital ulcer, it is characterized in that, according to parts by weight meter, by following raw material of Chinese medicine, being prepared from: 150~200 parts, 10~15 parts of Radix Angelicae Sinensis, 5~8 parts of Olibanums, 2~3 parts of the Radixs Angelicae Dahuricae, 1~2 part of red blood fat, 5~10 parts of old splendid achnatherums, 3~5 parts of Borneolum Syntheticums, 10~15 parts of Rhizoma Coptidis, 5~10 parts of Radix Scutellariaes, 1~2 part, Alumen, 80~120 parts, Oleum Sesami and vaseline.
2. a kind of Chinese medicine ointment for the treatment of decubital ulcer according to claim 1, it is characterized in that, according to parts by weight meter, by following raw material of Chinese medicine, being prepared from: 180 parts, 10 parts of Radix Angelicae Sinensis, 5 parts of Olibanums, 3 parts of the Radixs Angelicae Dahuricae, 1 part of red blood fat, 10 parts of old splendid achnatherums, 5 parts of Borneolum Syntheticums, 15 parts of Rhizoma Coptidis, 10 parts of Radix Scutellariaes, 1 part, Alumen, 100 parts, Oleum Sesami and vaseline.
3. a preparation method for the Chinese medicine ointment for the treatment of decubital ulcer claimed in claim 1, is characterized in that carrying out according to following steps:
(1) Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, red blood fat, old splendid achnatherum, Rhizoma Coptidis, Radix Scutellariae and Alumen are put into Oleum Sesami and soak 22~28h;
(2) after soaking, boil with high heat 45~90min;
(3) naturally cool to room temperature after removing slag, place 22~28h, then add the vaseline 30~60min that simmers in water to it;
(4) naturally cool to room temperature, then add the Borneolum Syntheticum 20~40min that simmers in water;
(5) naturally cool to room temperature, after autoclave sterilization, the Chinese medicine ointment of the decubital ulcer that can obtain medical treatment.
4. a kind of preparation method for the treatment of the Chinese medicine ointment of decubital ulcer according to claim 3, is characterized in that carrying out according to following steps:
(1) Radix Angelicae Sinensis, Olibanum, the Radix Angelicae Dahuricae, red blood fat, old splendid achnatherum, Rhizoma Coptidis, Radix Scutellariae and Alumen are put into Oleum Sesami and soak 24h;
(2) after soaking, boil with high heat 60min;
(3) naturally cool to room temperature after removing slag, place 24h, then add the vaseline 40min that simmers in water to it;
(4) naturally cool to room temperature, then add the Borneolum Syntheticum 30min that simmers in water;
(5) naturally cool to room temperature, after autoclave sterilization, the Chinese medicine ointment of the decubital ulcer that can obtain medical treatment.
CN201410317707.5A 2014-07-04 2014-07-04 Traditional Chinese medicine unguent for treating bedsores and preparation method of traditional Chinese medicine unguent for treating bedsores Pending CN104056066A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104491412A (en) * 2014-12-26 2015-04-08 齐方梅 Traditional Chinese medicine unguent for treating bedsore and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5270010A (en) * 1975-12-05 1977-06-10 Sankyo Co Ltd Preparation of diterpene alcohol
CN1548139A (en) * 2003-05-19 2004-11-24 魏茂武 Bedsore ointment and its prepn process

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5270010A (en) * 1975-12-05 1977-06-10 Sankyo Co Ltd Preparation of diterpene alcohol
CN1548139A (en) * 2003-05-19 2004-11-24 魏茂武 Bedsore ointment and its prepn process

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李素华: ""白及油治疗褥疮30例"", 《河北中医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104491412A (en) * 2014-12-26 2015-04-08 齐方梅 Traditional Chinese medicine unguent for treating bedsore and preparation method thereof

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Application publication date: 20140924