CN105079404A

CN105079404A - External traditional Chinese medicinal lotion for treating infective wound caused by multi-drug resistant bacteria

Info

Publication number: CN105079404A
Application number: CN201510586327.6A
Authority: CN
Inventors: 夏云强
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-09-07
Filing date: 2015-09-07
Publication date: 2015-11-25

Abstract

The invention discloses an external traditional Chinese medicinal lotion for treating infective wound caused by multi-drug resistant bacteria. In accordance with the pathogenesis of multi-drug resistant infective wound, the external lotion disclosed by the invention is prepared from the following traditional Chinese medicines which are capable of promoting blood circulation and removing stasis, clearing away heat and eliminating dampness, removing necrotic tissue and promoting generation of new tissue: thymifolious euphorbia herb, fortune silene herb with root, commen bomhax flower, root or bark of gluey litse, ophiorrhiza japonica, Japanese conehead herb, common squill bulb, circaeashape loosestrife herb and nipponian greenbrier rhizome and root. Upon clinical tests, total effective rate is 95%; and the external lotion is free from cross infection and is significant in curative effect.

Description

A kind of external washout with traditional Chinese herbs agent for the treatment of infective wound surface caused by multi-drug resistant bacteria

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of external washout with traditional Chinese herbs agent for the treatment of infective wound surface caused by multi-drug resistant bacteria.

Background technology

Multi-drug resistant bacteria (MDRO) refers to the antibacterial simultaneously in drug resistance to three classes of Clinical practice or the above antibiotic medicine of three classes.Along with the extensive use of broad ectrum antibiotic, there is the wound surface caused by multi-drug resistant bacteria, made treatment more difficult.Wound is caused infect many due to initial injury serious, extensive skin, fascia, muscular death, after wound surface pollutes, debridement is thorough, and pathogenic bacterium grow and cause in the tissue of downright bad inactivation.Through the surgical debridement drain of system, vacuum suction and antibiotic therapy, infective wound surface can be cured mostly, but there is part infected patient due to antibiotic overuse, indication select and usage and dosage lack of standardization, wound surface is caused to produce multi-drug resistant bacteria, be difficult in treatment select effective antibiotic, to this, application Chinese medicine has become the new way of current clinical research and treatment infective wound surface.According to clinical practice experience for many years, the external washout with traditional Chinese herbs agent of applicant's development, not only there is direct therapeutical effect, can also be cleaned wound surface by medicinal liquid, remove the slough of wound surface, reduce the quantity of wound surface pathogenic bacterium, avoid cambium to be destroyed, for the growth of granulation and wound repair create conditions, reach the object of putrefaction-removing granulation-promoting.The warm-heat effect of medicine also can promote local temperature in addition, improves the permeability of blood capillary, promotes local blood circulation and lymphatic return, be conducive to the conveying increasing wound surface growth desired nutritional material, eliminate pathological product, promote tissue repair, therapeutic effect is remarkable.

Summary of the invention

The object of this invention is to provide a kind of external washout with traditional Chinese herbs agent for the treatment of infective wound surface caused by multi-drug resistant bacteria.According to the principle of the traditional Chinese medical science " determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs ", " differential diagnosis of diseases combines with dialectical ", by differential diagnosis of diseases stove, distinguish the color of pus and thin, determine the good and evil deficiency and excess of disease.Stress differential diagnosis of diseases to combine with dialectical, for multidrug resistant infective wound surface, carry out dialectical in detail to the form of granulation, color, quality and exudate abnormal smells from the patient, distinguish the different pattern of syndrome of deficiency and excess, cold and heat, blood stasis, edema, in treatment by Chinese herbs, based on blood circulation promoting and blood stasis dispelling, heat clearing and damp drying, removing the necrotic tissue and promoting granulation.

The object of the invention is to be realized by following technical scheme, the external washout with traditional Chinese herbs agent of infective wound surface caused by this treatment multi-drug resistant bacteria is made up of the Chinese medicine of following weight portion: Herba Euphorbiae Thymifoliae 10-20 part, Herba silenes fortunei 30-40 part, Flos Bombacis Malabarici 6-8 part, Radix Seu Cortex Litseae Glutinosae 10-20 part, Herba ophiorrhizae japonicae 15-25 part, Herba Strobilanthis Japonici 9-15 part, Bulbus scillae scilloidis 3-9 part, Herba Lysimachiae Circaeoidis 4-8 part, Rhizoma Smilacis nipponicae 6-12 part.

Preferred: Herba Euphorbiae Thymifoliae 15 parts, Herba silenes fortunei 35 parts, Flos Bombacis Malabarici 7 parts, Radix Seu Cortex Litseae Glutinosae 15 parts, Herba ophiorrhizae japonicae 20 parts, Herba Strobilanthis Japonici 12 parts, Bulbus scillae scilloidis 6 parts, 6 parts, Herba Lysimachiae Circaeoidis, Rhizoma Smilacis nipponicae 9 parts.

Preparation method: traditionally make decoction.

Fang Zhong: Herba Euphorbiae Thymifoliae clearing away heat-damp and promoting diuresis, removing toxic substances, detumescence; Herba silenes fortunei clearing away heat-damp and promoting diuresis, invigorate blood circulation, tonify deficiency; Flos Bombacis Malabarici clearing away heat-damp and promoting diuresis, hemostasis, removing toxic substances; Radix Seu Cortex Litseae Glutinosae clearing away damp-heat, removing food stagnancy detumescence poison, wind-damp dispelling; Herba ophiorrhizae japonicae promoting blood circulation to remove blood stasis; Herba Strobilanthis Japonici repercussive, soothing liver-QI fall apart strongly fragrant, row water; Bulbus scillae scilloidis reducing swelling and alleviating pain, removing toxic substances are invigorated blood circulation; Herba Lysimachiae Circaeoidis detumescence and promoting granulation, eliminating stasis to stop pain, cooling blood for hemostasis; Rhizoma Smilacis nipponicae relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation and stopping pain.

Clinical data

1, physical data: this organizes in 40 examples, man 20 example, female 20 example; 18 ~ 45 years old age, average 29 years old; Site of pathological change: forearm and wrist portion 10 example, thigh 5 example, shank 15 example, foot 10 example; Traumatogenic reason: traffic accident wound 12 example, machine crush injury 16 example, weight injures 12 examples by a crashing object; Maximum 35cm × the 16cm of wound surface, minimum 12cm × 5cm; The longest 15a of the course of disease, the shortest 2 months, average 1.5a; Hospital stays 4 ~ 8w, average 50d; Bacteria cultivation results is multi-drug resistant bacteria.

2, Therapeutic Method: adopt external washout with traditional Chinese herbs treatment, medicine forms: take Herba Euphorbiae Thymifoliae 15g, Herba silenes fortunei 35g, Flos Bombacis Malabarici 7g, Radix Seu Cortex Litseae Glutinosae 15g, Herba ophiorrhizae japonicae 20g, Herba Strobilanthis Japonici 12g, Bulbus scillae scilloidis 6g, Herba Lysimachiae Circaeoidis 6g, Rhizoma Smilacis nipponicae 9g.Method: medicine-feeding is taken 2000 ~ 3000mL, pour in outer washbasin, thermodetector thermometric is 38 DEG C ~ 42 DEG C, bed upper berth macintoss, outer washbasin is put below suffering limb, open wound dressing, alternately irrigate with normal saline and hydrogen peroxide, remove surperficial slough and pus tongue, change tweezers, dip medicinal liquid washout wound surface with aseptic dressing, remove visible slough in wound surface, each washout 45min, then can with the sterile gauze flap coverage soaking lotion, sterile dressing, makes ingredient continue to play a role, and 7d is 1 course for the treatment of.Because the trauma infection contamination patient course of disease is long, healthy energy in chronic consumer, adds the long-term disunion of wound surface, and local is oozed out, and causes deficiency of qi and blood, deficiency-weakness of spleen-QI, therefore while external washout with traditional Chinese herbs treatment, needs to strengthen nutrition.

3, criterion of therapeutical effect: cure: red and swollen heat pain disappears, wound healing, granulation well-grown, and cicatrix is little and soft, wound healing 100%; Effective: red and swollen heat pain disappears, secretions without exception, wound is fresh and reduce, but granulation growth is not good enough, and wound healing is greater than 80%; Effective: red and swollen heat pain disappears slowly, and granulation is stale, has edema, wound exudates color is dark, wound healing 60% ~ 79%; Invalid: red and swollen heat pain is without improvement, and granulation does not grow, and has purulent secretion.

4, therapeutic outcome: this organizes the treatment of 40 examples through 4 ~ 6 courses for the treatment of, result cures 15 examples, effective 18 examples, effective 5 examples, and invalid 2 examples, cross infection case, does not appear in total effective rate 95%.

Detailed description of the invention

Embodiment one: take Herba Euphorbiae Thymifoliae 15g, Herba silenes fortunei 35g, Flos Bombacis Malabarici 7g, Radix Seu Cortex Litseae Glutinosae 15g, Herba ophiorrhizae japonicae 20g, Herba Strobilanthis Japonici 12g, Bulbus scillae scilloidis 6g, Herba Lysimachiae Circaeoidis 6g, Rhizoma Smilacis nipponicae 9g, traditionally make decoction.

Embodiment two: take Herba Euphorbiae Thymifoliae 20g, Herba silenes fortunei 30g, Flos Bombacis Malabarici 6g, Radix Seu Cortex Litseae Glutinosae 10g, Herba ophiorrhizae japonicae 15g, Herba Strobilanthis Japonici 9g, Bulbus scillae scilloidis 3g, Herba Lysimachiae Circaeoidis 4g, Rhizoma Smilacis nipponicae 12g, traditionally make decoction.

Embodiment three: take Herba Euphorbiae Thymifoliae 10g, Herba silenes fortunei 40g, Flos Bombacis Malabarici 8g, Radix Seu Cortex Litseae Glutinosae 20g, Herba ophiorrhizae japonicae 25g, Herba Strobilanthis Japonici 15g, Bulbus scillae scilloidis 9g, Herba Lysimachiae Circaeoidis 8g, Rhizoma Smilacis nipponicae 6g, traditionally make decoction.

Claims

1. treat an external washout with traditional Chinese herbs agent for infective wound surface caused by multi-drug resistant bacteria, it is characterized in that this external washout with traditional Chinese herbs agent is made up of the Chinese medicine of following weight portion: Herba Euphorbiae Thymifoliae 10-20 part, Herba silenes fortunei 30-40 part, Flos Bombacis Malabarici 6-8 part, Radix Seu Cortex Litseae Glutinosae 10-20 part, Herba ophiorrhizae japonicae 15-25 part, Herba Strobilanthis Japonici 9-15 part, Bulbus scillae scilloidis 3-9 part, Herba Lysimachiae Circaeoidis 4-8 part, Rhizoma Smilacis nipponicae 6-12 part.

2. a kind of external washout with traditional Chinese herbs agent for the treatment of infective wound surface caused by multi-drug resistant bacteria as claimed in claim 1, is characterized in that this external washout with traditional Chinese herbs agent is made up of the Chinese medicine of following weight portion: Herba Euphorbiae Thymifoliae 15 parts, Herba silenes fortunei 35 parts, Flos Bombacis Malabarici 7 parts, Radix Seu Cortex Litseae Glutinosae 15 parts, Herba ophiorrhizae japonicae 20 parts, Herba Strobilanthis Japonici 12 parts, Bulbus scillae scilloidis 6 parts, 6 parts, Herba Lysimachiae Circaeoidis, Rhizoma Smilacis nipponicae 9 parts.