CN105832909A - Traditional Chinese medicine preparation for treating necrotic ulcer of skin - Google Patents
Traditional Chinese medicine preparation for treating necrotic ulcer of skin Download PDFInfo
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- CN105832909A CN105832909A CN201610388846.6A CN201610388846A CN105832909A CN 105832909 A CN105832909 A CN 105832909A CN 201610388846 A CN201610388846 A CN 201610388846A CN 105832909 A CN105832909 A CN 105832909A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating the necrotic ulcer of skin. The traditional Chinese medicine preparation comprises orally-taken medicine and external-application medicine, wherein the orally-taken medicine comprises 10-20g of angelica sinensis, 10-20g of radix scrophulariae, 10-20g of salviae miltiorrhizae, 10-20g of caulis lonicerae, 10-15g of carthamus tinctorious, 8-12g of radix achyranthis bidentatae, 8-12g of viola philippica, 8-12g of radix glycyrrhizae, 10-20g of chrysanthemum, 10-15g of Tetrapanax papyriferus, 8-12g of herba lycopi and 8-12g of semen persicae; the external-application medicine comprises 8-12g of selaginella tamariscina, 10-15g of rhubarb, 3-5g of borneol, 8-12g of calcined gypsum, 8-12g of pearl powder, 8-12g of catechu, 8-12g of amber, 10-20g of olibanum, 10-15g of rhizoma coptidis and 10-15g of aloe. The traditional Chinese medicine preparation has the advantages that the medicinal materials of the traditional Chinese medicine preparation are excellently and reasonably combined to achieve synergic effects of tonifying, dredging collaterals, detoxifying, removing blood stasis, removing necrotic tissue, promoting granulation, and the like, oral administration and external application are combined to perform internal and external treatment so as to treat both the symptoms and the root causes, and the traditional Chinese medicine preparation is evident in curative effect and worthy of clinical popularization and application.
Description
Technical field
The invention belongs to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation treating cutaneous necrotizing ulcer.
Background technology
Cutaneous necrotizing ulcer is TCM surgery common disease, frequently-occurring disease, is with skin ulcer for Major Clinical table
Can not heal for Clinical symptoms for a long time, a kind of body surface disease of Skin preparation liquefaction infection and necrosis, this
Place refers to long-term person of not healing after TCM surgery sore class is burst.Owing to sore face is difficult to heal and consume very greatly, gives and suffer from
Person causes the biggest psychological pressure and economic loss, has a strong impact on the healthy of patient and quality of life.
Doctor trained in Western medicine is often the most highly desirable by drug therapy, sometimes for treating cutaneous necrotizing ulcer the most clinically
Need surgery skin grafting to treat, and the state of an illness is the most repeatedly, it is difficult to radical cure, so it is effective to need to find one
This disease treated by medicine.In recent years, we are according to tcm treatment according to syndrome differentiation, the principle for the treatment of a disease by looking into both its root cause and symptoms, it is provided that
A kind of instant effect, short treating period, the Orally taken and externally Chinese medicine preparation that has no side effect, be used for treating cutaneous necrotizing bursting
Ulcer achieves preferable effect.
Summary of the invention
The present invention solves the technical deficiency existed in terms for the treatment of cutaneous necrotizing ulcer at present, it is provided that one
Kind evident in efficacy, have no side effect, can inside and outside the Chinese medicine preparation ruling together, treat both principal and secondary aspect of disease.
The technical solution adopted in the present invention is:
A kind of Chinese medicine preparation treating cutaneous necrotizing ulcer, it is characterised in that in described Chinese medicine preparation includes
Taking medicine and medicine for external application, wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 10-20 gram, radix scrophulariae 10-20 gram, red sage root 10-20 gram, caulis lonicerae 10-20 gram, safflower 10-15
Gram, root of bidentate achyranthes 8-12 gram, Chinese violet 8-12 gram, 8-12 gram of Radix Glycyrrhizae, chrysanthemum 10-20 gram, stem pith of the rice-paper plant 10-15 gram,
Herba Lycopi 8-12 gram, 8-12 gram of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 8-12 gram, rheum officinale 10-15 gram, borneol 3-5 gram, calcined gypsum 8-12 gram, pearl powder 8-12
Gram, 8-12 gram of catechu, amber 8-12 gram, frankincense 10-20 gram, coptis 10-15 gram, aloe 10-15
Gram.
As a kind of prioritization scheme, described Chinese medicine preparation includes medicine for oral administration and medicine for external application,
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 10 grams, radix scrophulariae 10 grams, the red sage root 10 grams, caulis lonicerae 10 grams, 10 grams of safflower, the root of bidentate achyranthes 8 grams,
Chinese violet 8 grams, 8 grams of Radix Glycyrrhizae, chrysanthemum 10 grams, the stem pith of the rice-paper plant 10 grams, Herba Lycopi 8 grams, 8 grams of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 8 grams, rheum officinale 10 grams, borneol 3 grams, calcined gypsum 8 grams, pearl powder 8 grams, 8 grams of catechu,
Amber 8 grams, frankincense 10 grams, the coptis 10 grams, aloe 10 grams.
As a kind of prioritization scheme, described Chinese medicine preparation includes medicine for oral administration and medicine for external application:
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 12 grams, radix scrophulariae 12 grams, the red sage root 12 grams, caulis lonicerae 12 grams, 11 grams of safflower, the root of bidentate achyranthes 8 grams,
Chinese violet 9 grams, 9 grams of Radix Glycyrrhizae, chrysanthemum 12 grams, the stem pith of the rice-paper plant 11 grams, Herba Lycopi 8 grams, 9 grams of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 9 grams, rheum officinale 11 grams, borneol 3 grams, calcined gypsum 8 grams, pearl powder 9 grams, 8 grams of catechu,
Amber 8 grams, frankincense 12 grams, the coptis 11 grams, aloe 11 grams.
As a kind of prioritization scheme, described Chinese medicine preparation includes medicine for oral administration and medicine for external application:
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 14 grams, radix scrophulariae 14 grams, the red sage root 14 grams, caulis lonicerae 14 grams, 12 grams of safflower, the root of bidentate achyranthes 9 grams,
Chinese violet 9 grams, 9 grams of Radix Glycyrrhizae, chrysanthemum 14 grams, the stem pith of the rice-paper plant 12 grams, Herba Lycopi 9 grams, 9 grams of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 9 grams, rheum officinale 12 grams, borneol 4 grams, calcined gypsum 9 grams, pearl powder 9 grams, 9 grams of catechu,
Amber 9 grams, frankincense 14 grams, the coptis 12 grams, aloe 12 grams.
As a kind of prioritization scheme, described Chinese medicine preparation includes medicine for oral administration and medicine for external application:
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 16 grams, radix scrophulariae 16 grams, the red sage root 16 grams, caulis lonicerae 16 grams, 13 grams of safflower, the root of bidentate achyranthes 10
Gram, Chinese violet 10 grams, 10 grams of Radix Glycyrrhizae, chrysanthemum 16 grams, the stem pith of the rice-paper plant 13 grams, Herba Lycopi 10 grams, 10 grams of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 10 grams, rheum officinale 13 grams, borneol 4 grams, calcined gypsum 10 grams, pearl powder 10 grams, catechu 10
Gram, amber 10 grams, frankincense 16 grams, the coptis 13 grams, aloe 13 grams.
As a kind of prioritization scheme, described Chinese medicine preparation includes medicine for oral administration and medicine for external application:
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 18 grams, radix scrophulariae 18 grams, the red sage root 18 grams, caulis lonicerae 18 grams, 14 grams of safflower, the root of bidentate achyranthes 11
Gram, Chinese violet 11 grams, 11 grams of Radix Glycyrrhizae, chrysanthemum 18 grams, the stem pith of the rice-paper plant 14 grams, Herba Lycopi 11 grams, 11 grams of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 11 grams, rheum officinale 14 grams, borneol 5 grams, calcined gypsum 11 grams, pearl powder 11 grams, catechu 11
Gram, amber 11 grams, frankincense 18 grams, the coptis 14 grams, aloe 14 grams.
As a kind of prioritization scheme, described Chinese medicine preparation includes medicine for oral administration and medicine for external application:
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 20 grams, radix scrophulariae 20 grams, the red sage root 20 grams, caulis lonicerae 20 grams, 15 grams of safflower, the root of bidentate achyranthes 12
Gram, Chinese violet 12 grams, 12 grams of Radix Glycyrrhizae, chrysanthemum 20 grams, the stem pith of the rice-paper plant 15 grams, Herba Lycopi 12 grams, peach kernel 8-12
Gram；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 12 grams, rheum officinale 15 grams, borneol 5 grams, calcined gypsum 12 grams, pearl powder 12 grams, catechu 12
Gram, amber 12 grams, frankincense 20 grams, the coptis 15 grams, aloe 15 grams.
The instructions of taking of said medicine is: by Radix Angelicae Sinensis, radix scrophulariae, the red sage root, caulis lonicerae, safflower, the root of bidentate achyranthes,
Fourth, Radix Glycyrrhizae, chrysanthemum, the stem pith of the rice-paper plant, Herba Lycopi, peach kernel, after constant weight proportioning (adding and subtracting with disease) mixing,
According to the method decocting system of traditional fried Chinese medicine, potion, divided and warmly took for 2 times every day.Simultaneously by Selaginella tamariscina, rheum officinale,
Borneol, calcined gypsum, pearl powder, catechu, amber, frankincense, the coptis, aloe according to constant weight proportioning (with
Disease is added and subtracted) dry and be crushed into powder, it is applied in affected part after being in harmonious proportion uniformly, covers with hospital gauze and be fixed on skin
On, topical application of drug every day 2 times.It within 2 weeks, it is 1 course for the treatment of.
The raw material Chinese medicine of said medicine:
Radix Angelicae Sinensis, taste is pungent, warm in nature；Return liver, the heart, the spleen channel.There is replenishing and activating blood, effect of pain relieving ease constipation.
Radix scrophulariae, bitter, sweet, salty, cold in nature；Return lung, stomach, kidney channel.There is clearing heat and cooling blood, detoxicating and resolving a mass,
Effect of Yin-nourishing and body fluid promoting.
The red sage root, bitter, cold nature；The thoughts of returning home, pericardium, Liver Channel.Having promoting blood circulation, cool blood disappears carbuncle, supports
Effect of blood and tranquilizing mind.
Caulis lonicerae, taste is sweet, cold in nature.The thoughts of returning home, lung channel.Have clearing heat and detoxicating, effect of dispelling wind dredging collateral, main
Control warm disease heating, sore and toxic, toxic-heat and blood stasis, beriberoid pyretic arthralgia.
Safflower, taste is pungent, warm in nature；The thoughts of returning home, Liver Channel.Having invigorates blood circulation stimulates the menstrual flow, effect of blood stasis removing analgesic.
The root of bidentate achyranthes, bitter, acid, property is put down；Return liver, kidney channel.Have nourishing liver and kidney, strengthen muscles and bones, invigorating blood circulation
The stasis of blood, effect of inducing diuresis for treating strangurtia.
Chinese violet, bitter, pungent, cold in nature；The thoughts of returning home, Liver Channel.Have clearing heat and detoxicating, effect of cool blood detumescence.
Radix Glycyrrhizae, taste is sweet, and property is put down；The thoughts of returning home, spleen, lung, stomach warp.Have and invigorate the spleen and benefit qi, clearing heat and detoxicating, dispel
Phlegm and relieving cough, relieving spasm to stop pain, effect of coordinating the drug actions of a prescription
Chrysanthemum, taste is micro-pungent, sweet, bitter, cold nature.There is dispelling wind and heat from the body, clear liver and improve vision, flat liver-yang, solve
Effect of poison.
The stem pith of the rice-paper plant, taste is sweet, light, warm in nature；Attach to the lung and stomach meridians.There is clearing away heat and promoting diuresis, effect of the logical breast of ventilation.
Herba Lycopi, nature and flavor are bitter, pungent, tepor；Return liver, bladder warp.Having invigorates blood circulation stimulates the menstrual flow, the merit of line water detumescence
Effect.
Peach kernel, taste is sweet, bitter, and property is put down；Return lung, liver, large intestine channel.There is promoting blood circulation, moisturize laxation it
Effect.
Selaginella tamariscina, taste is pungent, and property is put down.Return spleen, liver two warp.Have broken blood dissipate the stasis of blood, promoting blood circulation and hemostasis, relieving cough and reducing sputum,
Clearing and activating the channels and collaterals effect.
Rheum officinale, bitter, cold in nature；Return spleen, stomach, large intestine, liver, pericardium channel.There is heat and toxic materials clearing away, heat-clearing
Purging intense heat, removing pattogenic heat from the blood and toxic material from the body, effect of promoting blood circulation.
Borneol, taste is pungent, bitter, cold nature；The thoughts of returning home, spleen, lung channel.There is open-minded phlegm of having one's ideas straightened out, swelling and pain relieving,
Effect of relieving summer-heat inducing resuscitation.
Calcined gypsum, taste is sweet, pungent, puckery, cold in nature.Attach to the lung and stomach meridians.There is expelling pathogenic factors from muscles for clearing heat, relieving restlessness quenches the thirst,
Clearing heat and detoxicating, effect of purging intense heat, forge apply can myogenic sore.
Pearl powder, taste is sweet, salty, cold in nature；The thoughts of returning home, Liver Channel.Having arresting convulsion of calming the nerves, improving eyesight disappears screen, removing toxic substances
Effect of myogenic.
Catechu, bitter, puckery, cool in nature.The thoughts of returning home, lung channel.There is clearing heat and eliminating phlegm, promote the production of body fluid to quench thirst, dicynone
Bitterly, effect of hygroscopic sore.Dextrorotation cachou extract is excited after first suppressing the in vitro heart；Tyrosine decarboxylation can be suppressed
The activity of enzyme, suppresses hyaluronidase, choline acetylase, streptokinase can be suppressed fibrinous dissolving
Effect；In vitro test various skin fungi and staphylococcus aureus, multiple bacillus etc. are had necessarily suppress make
With.
Amber, taste is sweet, property is flat；The thoughts of returning home, liver, small intestine, bladder, lung, the spleen channel.There is tranquillizing the mind by relieving convulsion,
Dissipate stasis of blood hemostasis, promoting diuresis for stranguria, go effect of screen improving eyesight.
Frankincense, taste is pungent, bitter, warm in nature；The thoughts of returning home, liver, the spleen channel.There is promoting blood circulation and stopping pain, the merit of detumescence and promoting granulation
Effect.
The coptis, bitter, cold in nature；The thoughts of returning home, stomach, liver, large intestine channel.There is effect of heat-clearing poison.
Aloe, bitter, cold in nature；Return liver, stomach, large intestine channel.There is purging liver-heat, effect of relieving constipation by purgation.
Cutaneous necrotizing ulcer is TCM surgery common disease, frequently-occurring disease.Western medicine treatment focuses mostly on and is preventing wound
Face is infected and protects the surface of a wound, such as anti-infective, surgical debridement, skin grafting, multiple dressing and the surface of a wound
Covering, vitamins and zinc preparation etc. are treated or by external application growth factor to regulate and control wound healing, have certain
Curative effect.Traditional Chinese medicine is thought, chronic ulcer of skin, and clinical common surface of a wound difficulty holds back difficult receipts, add more than through repeatedly
Clear sore, multi-medicament infiltration etc. is treated.Therefore healthy tendency is deficient, venation block, unable torr poison leaks, and makes evil nothing
Outlet, Shi Re Bing Pian pents up for morbidity Chief amongst.Treatment is when for above-mentioned basic pathogenesis, formulating phase
" benefit ", " leading to ", " clearly " principle of reatment answered.
In Chinese medicine of the present invention, in medicine for oral administration, Radix Angelicae Sinensis, radix scrophulariae, the red sage root, root of bidentate achyranthes energy replenishing and activating blood, benefit gas are supported
The moon, treats insufficiency of vital energy and blood, network road virtual loss, can improve body strengthening vital QI to eliminate pathogenic factors ability, fill up network road, helps to foster new
Flesh grows；Caulis lonicerae, Chinese violet, chrysanthemum heat-clearing, removing toxic substances, cool blood, disappear carbuncle, toxic dampness and heat in removing body,
Play effect of detumescence and drawing out poison；Safflower, peach kernel, Herba Lycopi's promoting blood circulation to remove blood stasis, inducing meastruation to relieve menalgia, promote that blood is micro-and follow
Ring, improves hemodynamic, dissipating blood stasis with potent drugs.The stem pith of the rice-paper plant, Herba Lycopi's clearing damp and promoting diuresis, root of bidentate achyranthes diversion is descending, promotes body
Endotoxic quick discharge；Radix Glycyrrhizae can invigorate the spleen and benefit qi, clearing heat and detoxicating, again can coordinating the drug actions of a prescription, make all medicines it
Bias is alleviated, and is allowed to coordinated with each other, jointly completes its therapeutic action.In medicine for external application, calcined gypsum,
Pearl powder, aloe, frankincense are clearing heat and detoxicating, promoting blood circulation and stopping pain, detumescence and promoting granulation, and medicine directly acts on focus,
Removing degeneration necrosis tissue, improves skin metabolism, promotes the growth of neoplastic skin tissue；Borneol, Huang
Company, catechu, rheum officinale energy heat-clearing and damp-drying drug, purge heat removing toxic substances energy cooling and activating blood, effectively suppression skin histology table
The various fungies in face, play disinfecting, antimicrobial anti-infectious function, promote the healing of the surface of a wound；Amber, Selaginella tamariscina dissipate the stasis of blood
Hemostasis, clearing and activating the channels and collaterals, can search that to pick the stasis of blood of channels turbid, make channels sensible, turbid allization of the stasis of blood.All medicine compatibilities are superior,
Reasonable recipe, plays help, dredging collateral, removing toxic substances, stagnation resolvation, corruption, the myogenic etc. of dispelling effect altogether, Orally taken and externally, interior
Outer conjunction controls, treats both principal and secondary aspect of disease, evident in efficacy, clinic is promoted and uses.
For investigating the clinical efficacy of medicine of the present invention further, we choose the 76 cutaneous necrotizing ulcers of example
Carry out clinical testing, the maleest 41 examples, female 35 example；Upper limbs 36 example, lower limb 40 example；12 years old-71 age
Year, average 37 years old；The shortest person of the course of disease 1.5 months, elder 482 months, average (29.35 ± 83.25)
Individual month；The initial surface of a wound area reckling 2cm2, the maximum 380cm2, average (22.78 ± 50.26) cm2；
All patients are randomly divided into treatment group and control group, often organize 38 examples.Two groups of patients are in age, the course of disease, morbidity
Position, pathogenic factor aspect no significant difference (P ＞ 0.05), have comparativity.
Diagnostic criteria:
Wound, bacterium infect or other diseases causes skin infection, ulcer surface to have secretion to ooze out, and edge is dark
Purple, skin depth, there are cellulose, purulence tongue or have granulation tissue to grow, ulceration is as deep as skin histology muscle, bone group
Knit or prolonged do not heal.
Methods for the treatment of:
Treatment group: take Radix Angelicae Sinensis 14 grams, radix scrophulariae 14 grams, the red sage root 14 grams, caulis lonicerae 14 grams, 12 grams of safflower,
The root of bidentate achyranthes 9 grams, Chinese violet 9 grams, 9 grams of Radix Glycyrrhizae, chrysanthemum 14 grams, the stem pith of the rice-paper plant 12 grams, Herba Lycopi 9 grams, peach kernel 9
Gram (adding and subtracting with disease), takes after decocting, and every day, potion, point warmly took for 2 times.Simultaneously by Selaginella tamariscina 9 grams, rheum officinale
12 grams, borneol 4 grams, calcined gypsum 9 grams, pearl powder 9 grams, 9 grams of catechu, amber 9 grams, frankincense 14 grams,
The coptis 12 grams, aloe 12 grams (adding and subtracting with disease) are dried after being crushed into powder, and are in harmonious proportion and are uniformly externally applied to injury,
Topical application of drug every day 2 times.Within 2 weeks, it is a course for the treatment of, 1-2 the course for the treatment of of general treatment.
Control group: external application Kangfuxin Liquid (Inner Mongolia Jingxin Pharmaceutical Co., Ltd., traditional Chinese medicines quasi-word Z15020805),
Apply affected part after being impregnated with liquid with hospital gauze, rinse by this product again after the debridement of infective wound surface elder generation, and with being impregnated with this
The gauze filling of product or application, change dressings and be once advisable every day.
Criterion of therapeutical effect:
Clinical cure: ulcer healing, follows up a case by regular visits at 1 month ulcer without recurrence；
Effective: ulceration is gradually reduced, cleaning, there is fresh granulation tissue to grow；
Invalid: ulceration is unchanged, need operative treatment.
Efficacy result:
1, comparitive study:
After treatment, treatment group cures 22 examples, effective 13 examples, invalid 3 examples, and cure rate is 57.9%, always has
Efficiency 92.1%；Control group cures 14 examples, effective 16 examples, invalid 8 examples, and cure rate is 36.8%, always has
Efficiency 80.0%；Treatment group cure rate and efficient apparently higher than control group (two groups of results compare P ＜ 0.05,
Difference is statistically significant).Detailed results is shown in Table 1.
Curative effect comparision result table after 1: two group of case treatment of table
| Group | Number of cases | Cure n (%) | Effectively n (%) | Invalid n (%) | Total effective rate (%) |
| Treatment group | 38 | 22(57.9) | 13(34.2) | 3(7.95) | 92.1 |
| Control group | 38 | 14(36.8) | 16(42.10) | 8(21.1) | 80.0 |
2, ulcer surface healing time and recurrence compare:
Observing two groups of patient skin ulcer surface healing times and recurrence, treatment group wound healing time is less than
Control group, comparing difference for two groups has conspicuousness (P ＜ 0.05)；After healing, following up a case by regular visits in half a year, treatment group is multiple
Sending out 2 examples, control group recurs 10 examples, and comparing difference for two groups has conspicuousness (P ＜ 0.05).Detailed results is shown in Table
2。
2: two groups of ulcer surface healing times of table and recurrence compare
| Packet | Number of cases | Ulcer surface healing time | Recurrence | Recurrence rate |
| Treatment group | 38 | 23.6±11.2 | 2 | 5.3% |
| Control group | 38 | 33.4±11.3 | 10 | 26.3% |
3, side effect is compared:
During whole clinical observation, all patients have no obvious adverse reaction.
Result shows, Chinese medicine preparation of the present invention is for oral administration can nurse one's health the vital organs of the human body, improves immunity of organisms and cell
Vigor, external application can be by the through pathology in local, anti-inflammation, putrefaction-removing granulation-promoting, the healing of quickening skin ulcer face,
There are the advantages such as instant effect, cure rate is high, recurrence rate is low and has no side effect, clinic promotion and application.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation treating cutaneous necrotizing ulcer, chooses medicine for oral administration and medicine for external application, its
In, medicine for oral administration includes: Radix Angelicae Sinensis 10 grams, radix scrophulariae 10 grams, the red sage root 10 grams, caulis lonicerae 10 grams, safflower 10
Gram, the root of bidentate achyranthes 8 grams, Chinese violet 8 grams, 8 grams of Radix Glycyrrhizae, chrysanthemum 10 grams, the stem pith of the rice-paper plant 10 grams, Herba Lycopi 8 grams, peach
Benevolence 8 grams；Medicine for external application includes: Selaginella tamariscina 8 grams, rheum officinale 10 grams, borneol 3 grams, calcined gypsum 8 grams, pearl powder
8 grams, 8 grams of catechu, amber 8 grams, frankincense 10 grams, the coptis 10 grams, aloe 10 grams.
Embodiment 2: a kind of Chinese medicine preparation treating cutaneous necrotizing ulcer, chooses medicine for oral administration and medicine for external application, its
In, medicine for oral administration includes: Radix Angelicae Sinensis 12 grams, radix scrophulariae 12 grams, the red sage root 12 grams, caulis lonicerae 12 grams, safflower 11
Gram, the root of bidentate achyranthes 8 grams, Chinese violet 9 grams, 9 grams of Radix Glycyrrhizae, chrysanthemum 12 grams, the stem pith of the rice-paper plant 11 grams, Herba Lycopi 8 grams, peach
Benevolence 9 grams；Medicine for external application includes: Selaginella tamariscina 9 grams, rheum officinale 11 grams, borneol 3 grams, calcined gypsum 8 grams, pearl powder
9 grams, 8 grams of catechu, amber 8 grams, frankincense 12 grams, the coptis 11 grams, aloe 11 grams.
Embodiment 3: a kind of Chinese medicine preparation treating cutaneous necrotizing ulcer, chooses medicine for oral administration and medicine for external application, its
In, medicine for oral administration includes: Radix Angelicae Sinensis 14 grams, radix scrophulariae 14 grams, the red sage root 14 grams, caulis lonicerae 14 grams, safflower 12
Gram, the root of bidentate achyranthes 9 grams, Chinese violet 9 grams, 9 grams of Radix Glycyrrhizae, chrysanthemum 14 grams, the stem pith of the rice-paper plant 12 grams, Herba Lycopi 9 grams, peach
Benevolence 9 grams；Medicine for external application includes: Selaginella tamariscina 9 grams, rheum officinale 12 grams, borneol 4 grams, calcined gypsum 9 grams, pearl powder
9 grams, 9 grams of catechu, amber 9 grams, frankincense 14 grams, the coptis 12 grams, aloe 12 grams.
Embodiment 4: a kind of Chinese medicine preparation treating cutaneous necrotizing ulcer, chooses medicine for oral administration and medicine for external application, its
In, medicine for oral administration includes: Radix Angelicae Sinensis 16 grams, radix scrophulariae 16 grams, the red sage root 16 grams, caulis lonicerae 16 grams, safflower 13
Gram, the root of bidentate achyranthes 10 grams, Chinese violet 10 grams, 10 grams of Radix Glycyrrhizae, chrysanthemum 16 grams, the stem pith of the rice-paper plant 13 grams, Herba Lycopi 10 grams,
10 grams of peach kernel；Medicine for external application includes: Selaginella tamariscina 10 grams, rheum officinale 13 grams, borneol 4 grams, calcined gypsum 10 grams,
Pearl powder 10 grams, 10 grams of catechu, amber 10 grams, frankincense 16 grams, the coptis 13 grams, aloe 13 grams.
Embodiment 5: a kind of Chinese medicine preparation treating cutaneous necrotizing ulcer, chooses medicine for oral administration and medicine for external application, its
In, medicine for oral administration includes: Radix Angelicae Sinensis 18 grams, radix scrophulariae 18 grams, the red sage root 18 grams, caulis lonicerae 18 grams, safflower 14
Gram, the root of bidentate achyranthes 11 grams, Chinese violet 11 grams, 11 grams of Radix Glycyrrhizae, chrysanthemum 18 grams, the stem pith of the rice-paper plant 14 grams, Herba Lycopi 11 grams,
11 grams of peach kernel；Medicine for external application includes: Selaginella tamariscina 11 grams, rheum officinale 14 grams, borneol 5 grams, calcined gypsum 11 grams,
Pearl powder 11 grams, 11 grams of catechu, amber 11 grams, frankincense 18 grams, the coptis 14 grams, aloe 14 grams.
Embodiment 6: a kind of Chinese medicine preparation treating cutaneous necrotizing ulcer, chooses medicine for oral administration and medicine for external application, its
In, medicine for oral administration includes: Radix Angelicae Sinensis 20 grams, radix scrophulariae 20 grams, the red sage root 20 grams, caulis lonicerae 20 grams, safflower 15
Gram, the root of bidentate achyranthes 12 grams, Chinese violet 12 grams, 12 grams of Radix Glycyrrhizae, chrysanthemum 20 grams, the stem pith of the rice-paper plant 15 grams, Herba Lycopi 12 grams,
8-12 gram of peach kernel；Medicine for external application includes: Selaginella tamariscina 12 grams, rheum officinale 15 grams, borneol 5 grams, calcined gypsum 12 grams,
Pearl powder 12 grams, 12 grams of catechu, amber 12 grams, frankincense 20 grams, the coptis 15 grams, aloe 15 grams.
Below by concrete case, the curative effect of medication of the present invention is verified further:
Case 1
Zhang, man, 43 years old.Under patient's left hand butt, local swelling is obvious, blister occurs and change at rear swelling
Purulence, is shown in a small amount of yellow-white stiff fester after needling blister voluntarily, crevasse thereafter is prolonged does not heals, and flaring is big,
About 3cm × 4cm sore face is seen in the back of the hand center, and open sore part periphery is faint yellow manadesma, and central authorities are furvous necrosis group
Knitting, red tongue body, tongue is thin in vain, wiry and frequent pulse.With cutaneous necrotizing ulcer treatment.Prescription: Radix Angelicae Sinensis 10 grams, profound
Join 10 grams, the red sage root 10 grams, caulis lonicerae 10 grams, 10 grams of safflower, the root of bidentate achyranthes 8 grams, Chinese violet 8 grams, Radix Glycyrrhizae 8
Gram, chrysanthemum 10 grams, the stem pith of the rice-paper plant 10 grams, Herba Lycopi 8 grams, 8 grams of peach kernel, sooner or later warmly take for twice, separately after decocting
With Selaginella tamariscina 8 grams, rheum officinale 10 grams, borneol 3 grams, calcined gypsum 8 grams, pearl powder 8 grams, 8 grams of catechu, amber
Amber 8 grams, frankincense 10 grams, the coptis 10 grams, aloe 10 grams, drying is crushed into powder, and smears after being in harmonious proportion uniformly
In affected part, cover with hospital gauze and be fixed on skin, topical application of drug every day 2 times.Through controlling 2 weeks, locally sore face
Central authorities' purulence corruption is the most most, white tendon exposed, and sees that cerise granulation grows, and the purulence corruption of open sore part edge still has, point
Secretion is more, sore week the colour of skin stasis of blood dark.1 week again, sore face was little, and the purulence corruption of open sore part edge is the most most, and epithelium climbs life
Substantially, the exposed tendon of sore face central authorities is completely covered, granulation well-grown, sore week the stasis of blood dark, continuous take 1
In week, heal in sore face.Follow up a case by regular visits to have no recurrence half a year.
Medical record 2
Shut out certain, man, 50 years old.Patient is because being failed to treat in time by wound, and swelling is obvious to cause left hand three to refer to,
The colour of skin is micro-red, skin Wen Bugao, the sore face of one 2cm × 4cm seen from ulnar side, above has yellowish-brown scab lid to adhere to, sore
Face is drier, and a small amount of faint yellow pus seen from extruding scab lid oozes out, and the most very, finger flex is unfavorable for tenderness, tongue
Matter is the reddest, yellow,greasy and thin fur, small and wiry pulse.Auxiliary examination: x-ray is taken the photograph sheet and pointed out joint bone absorption in left forefinger.Purulence
Liquid Bacteria Culture shows staphylococcus aureus growth.With drug therapy of the present invention, prescription: Radix Angelicae Sinensis 16 grams, profound
Join 16 grams, the red sage root 16 grams, caulis lonicerae 16 grams, 13 grams of safflower, the root of bidentate achyranthes 10 grams, Chinese violet 10 grams, sweet
Grass 10 grams, chrysanthemum 16 grams, the stem pith of the rice-paper plant 13 grams, Herba Lycopi 10 grams, 10 grams of peach kernel, twice temperature of morning and evening after decocting
Clothes, another with Selaginella tamariscina 10 grams, rheum officinale 13 grams, borneol 4 grams, calcined gypsum 10 grams, pearl powder 10 grams, youngster
Tea 10 grams, amber 10 grams, frankincense 16 grams, the coptis 13 grams, aloe 13 grams, drying is crushed into powder, and adjusts
It is applied in affected part after uniformly, covers with hospital gauze and be fixed on skin, topical application of drug every day 2 times.Through controlling 1
In week, scab gradually takes off, it is seen that faint yellow fascia tissue, and sore face is oozed out substantially, and 7 days again, surface of a wound purulence corruption was the most most,
Granulation tissue look scarlet, sore week epithelium climb raw slowly, continual cure is the healing of sore face after 1 week, and forefinger bends and stretches extensive
Multiple normal.Follow up a case by regular visits to three months have no recurrence.
Case 3
In certain, female, 28 years old.Patient's left lower extremity burnt degree ulceration does not hold back more than 1 year.After hospitalization, remove
Outside not healing at nearly ankle below left leg, remaining is all formed a scab, therefore leaves hospital and change dressings voluntarily, after this sore face the most gradually tie
Scab.About after half a year, the former burn surface of patient's left leg occurs that many places are oozed out, and right leg also occurs that ulceration oozes out afterwards.
Double lower limb ulceration sore faces are gradually increased.Tossing about in bed many City Hospitals treatments once, the surface of a wound is not healed, the phase
Between row skin grafting twice, skin flap is also shown in necrosis of festering, and the surface of a wound still fails healing, then treats with we.
Take Radix Angelicae Sinensis 20 grams, radix scrophulariae 20 grams, the red sage root 20 grams, caulis lonicerae 20 grams, 15 grams of safflower, the root of bidentate achyranthes 12 grams,
Chinese violet 12 grams, 12 grams of Radix Glycyrrhizae, chrysanthemum 20 grams, the stem pith of the rice-paper plant 15 grams, Herba Lycopi 12 grams, 8-12 gram of peach kernel,
Sooner or later warmly take for twice after decocting, another with Selaginella tamariscina 12 grams, rheum officinale 15 grams, borneol 5 grams, calcined gypsum 12 grams,
Pearl powder 12 grams, 12 grams of catechu, amber 12 grams, frankincense 20 grams, the coptis 15 grams, aloe 15 grams,
Drying is crushed into powder, and is applied in affected part after being in harmonious proportion uniformly, covers with hospital gauze and is fixed on skin, every day
The topical application of drug 2 times.After 2 weeks, lower limb distending pain alleviates, and surface of a wound area is obviously reduced, and purulence corruption is the most most, and granulation look the most inclined
Secretly, oozing out thin, amount is many, 1 week again, and heal substantially in the left leg of patient and left forearm sore face, skin at left leg
The colour of skin is dark, and keloid is obvious, and sore face is merged, only remaining left leg one 2cm × 1.8cm sore face, sore face, remaining place
The most healing, continual cure is after 1 week, and all surface of a wound all heal.Effect of follow-up visit by telephone has no recurrence half a year.
Claims (7)
1. the Chinese medicine preparation treating cutaneous necrotizing ulcer, it is characterised in that described Chinese medicine preparation includes
Medicine for oral administration and medicine for external application, wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 10-20 gram, radix scrophulariae 10-20 gram, red sage root 10-20 gram, caulis lonicerae 10-20 gram, safflower 10-15
Gram, root of bidentate achyranthes 8-12 gram, Chinese violet 8-12 gram, 8-12 gram of Radix Glycyrrhizae, chrysanthemum 10-20 gram, stem pith of the rice-paper plant 10-15 gram,
Herba Lycopi 8-12 gram, 8-12 gram of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 8-12 gram, rheum officinale 10-15 gram, borneol 3-5 gram, calcined gypsum 8-12 gram, pearl powder 8-12
Gram, 8-12 gram of catechu, amber 8-12 gram, frankincense 10-20 gram, coptis 10-15 gram, aloe 10-15
Gram.
Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation includes taking orally
Medicine and medicine for external application,
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 10 grams, radix scrophulariae 10 grams, the red sage root 10 grams, caulis lonicerae 10 grams, 10 grams of safflower, the root of bidentate achyranthes 8 grams,
Chinese violet 8 grams, 8 grams of Radix Glycyrrhizae, chrysanthemum 10 grams, the stem pith of the rice-paper plant 10 grams, Herba Lycopi 8 grams, 8 grams of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 8 grams, rheum officinale 10 grams, borneol 3 grams, calcined gypsum 8 grams, pearl powder 8 grams, 8 grams of catechu,
Amber 8 grams, frankincense 10 grams, the coptis 10 grams, aloe 10 grams.
Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation includes taking orally
Medicine and medicine for external application,
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 12 grams, radix scrophulariae 12 grams, the red sage root 12 grams, caulis lonicerae 12 grams, 11 grams of safflower, the root of bidentate achyranthes 8 grams,
Chinese violet 9 grams, 9 grams of Radix Glycyrrhizae, chrysanthemum 12 grams, the stem pith of the rice-paper plant 11 grams, Herba Lycopi 8 grams, 9 grams of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 9 grams, rheum officinale 11 grams, borneol 3 grams, calcined gypsum 8 grams, pearl powder 9 grams, 8 grams of catechu,
Amber 8 grams, frankincense 12 grams, the coptis 11 grams, aloe 11 grams.
Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation includes taking orally
Medicine and medicine for external application,
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 14 grams, radix scrophulariae 14 grams, the red sage root 14 grams, caulis lonicerae 14 grams, 12 grams of safflower, the root of bidentate achyranthes 9 grams,
Chinese violet 9 grams, 9 grams of Radix Glycyrrhizae, chrysanthemum 14 grams, the stem pith of the rice-paper plant 12 grams, Herba Lycopi 9 grams, 9 grams of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 9 grams, rheum officinale 12 grams, borneol 4 grams, calcined gypsum 9 grams, pearl powder 9 grams, 9 grams of catechu,
Amber 9 grams, frankincense 14 grams, the coptis 12 grams, aloe 12 grams.
Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation includes taking orally
Medicine and medicine for external application,
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 16 grams, radix scrophulariae 16 grams, the red sage root 16 grams, caulis lonicerae 16 grams, 13 grams of safflower, the root of bidentate achyranthes 10
Gram, Chinese violet 10 grams, 10 grams of Radix Glycyrrhizae, chrysanthemum 16 grams, the stem pith of the rice-paper plant 13 grams, Herba Lycopi 10 grams, 10 grams of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 10 grams, rheum officinale 13 grams, borneol 4 grams, calcined gypsum 10 grams, pearl powder 10 grams, catechu 10
Gram, amber 10 grams, frankincense 16 grams, the coptis 13 grams, aloe 13 grams.
Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation includes taking orally
Medicine and medicine for external application,
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 18 grams, radix scrophulariae 18 grams, the red sage root 18 grams, caulis lonicerae 18 grams, 14 grams of safflower, the root of bidentate achyranthes 11
Gram, Chinese violet 11 grams, 11 grams of Radix Glycyrrhizae, chrysanthemum 18 grams, the stem pith of the rice-paper plant 14 grams, Herba Lycopi 11 grams, 11 grams of peach kernel；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 11 grams, rheum officinale 14 grams, borneol 5 grams, calcined gypsum 11 grams, pearl powder 11 grams, catechu 11
Gram, amber 11 grams, frankincense 18 grams, the coptis 14 grams, aloe 14 grams.
Chinese medicine preparation the most according to claim 1, it is characterised in that described Chinese medicine preparation includes taking orally
Medicine and medicine for external application,
Wherein, described medicine for oral administration is made up of the Chinese herb of following weight portion:
Radix Angelicae Sinensis 20 grams, radix scrophulariae 20 grams, the red sage root 20 grams, caulis lonicerae 20 grams, 15 grams of safflower, the root of bidentate achyranthes 12
Gram, Chinese violet 12 grams, 12 grams of Radix Glycyrrhizae, chrysanthemum 20 grams, the stem pith of the rice-paper plant 15 grams, Herba Lycopi 12 grams, peach kernel 8-12
Gram；
Described medicine for external application is made up of the Chinese herb of following weight portion:
Selaginella tamariscina 12 grams, rheum officinale 15 grams, borneol 5 grams, calcined gypsum 12 grams, pearl powder 12 grams, catechu 12
Gram, amber 12 grams, frankincense 20 grams, the coptis 15 grams, aloe 15 grams.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107158163A (en) * | 2017-07-12 | 2017-09-15 | 田娟 | It is a kind of to repair the restorative procedure of the downright bad hemotoncus oedema of skin depressions caused by liposuction |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1254567A (en) * | 1998-11-24 | 2000-05-31 | 朱湘生 | Ulcer medicine |
| CN102416089A (en) * | 2011-11-18 | 2012-04-18 | 韩传瑞 | Externally applied traditional Chinese medicine ointment and preparation method thereof |
| CN103655771A (en) * | 2012-09-03 | 2014-03-26 | 上海中医药大学附属龙华医院 | Traditional Chinese medicine preparation for treating skin ulcers and preparation method thereof |
-
2016
- 2016-06-02 CN CN201610388846.6A patent/CN105832909A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1254567A (en) * | 1998-11-24 | 2000-05-31 | 朱湘生 | Ulcer medicine |
| CN102416089A (en) * | 2011-11-18 | 2012-04-18 | 韩传瑞 | Externally applied traditional Chinese medicine ointment and preparation method thereof |
| CN103655771A (en) * | 2012-09-03 | 2014-03-26 | 上海中医药大学附属龙华医院 | Traditional Chinese medicine preparation for treating skin ulcers and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107158163A (en) * | 2017-07-12 | 2017-09-15 | 田娟 | It is a kind of to repair the restorative procedure of the downright bad hemotoncus oedema of skin depressions caused by liposuction |
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Application publication date: 20160810 |