CN104825629A - Traditional Chinese medicine compound externally-applied coating liquid for treatment of diabetic foot ulcers - Google Patents
Traditional Chinese medicine compound externally-applied coating liquid for treatment of diabetic foot ulcers Download PDFInfo
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- CN104825629A CN104825629A CN201510203181.2A CN201510203181A CN104825629A CN 104825629 A CN104825629 A CN 104825629A CN 201510203181 A CN201510203181 A CN 201510203181A CN 104825629 A CN104825629 A CN 104825629A
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Abstract
The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine compound externally-applied coating liquid for treatment of diabetic foot ulcers; the traditional Chinese medicine compound externally-applied coating liquid is prepared from the following traditional Chinese medicine raw materials in parts by weight: 18-22 g of honeysuckle, 18-22 g of pilea peltata hance, 10-14 g of hibiscus schizopetalus, 10-14 g of dandelion, 10-14 g of sargentgloryvine stem, 18-22 g of cortex moutan, 10-14 g of rhizoma corydalis, 18-22 g of salix hypoleuca, 18-22 g of fructus chebulae, 13-17 g of herb of pilea lomatogramma, 13-17 g of radix sophorae flavescentis, 13-17 g of ampelopsis japonica, 10-14 g of radix angelicae and 10-14 g of herb of cordate circaea. Through traditional Chinese medicine conditioning, all the medicines are in compatibility, and the traditional Chinese medicine compound externally-applied coating liquid is capable of diminishing inflammation and sterilizing, promoting cell regeneration of affected tissues, promoting blood circulation to remove blood stasis, and removing necrotic tissues and promoting granulation, has no allergic reaction, promotes wound surfaces to be quickly healed, also has the advantages of simple preparation and low cost, is suitable for skin ulcer, especially is suitable for treatment of diabetic foot gangrene, and significantly reduces the amputation rate of patients.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of Chinese medicine compound externally used coating liquid for the treatment of diabetic foot ulcer.
Background technology
Society people, due to heredity and unsound life style, the sickness rate that result in diabetes increases year by year, and incident complication-diabetic foot gangrene, decubital ulcer etc. significantly increase.This complication of western medical treatment adopts sterilization and route dressing change usually, because patient suffers from diabetes, and local microcirculation obstacle, cell is difficult to regeneration, cause ulcer to be difficult to healing, severe patient even has to cut out suffering limb, causes serious infringement to the psychology of patient and physiology.
Summary of the invention
The invention provides a kind of Chinese medicine compound externally used coating liquid for the treatment of diabetic foot ulcer, adopt this medicine succinctly can carry out anti-inflammation and sterilization easily, the cell regeneration of affected tissue can be impelled, blood circulation promoting and blood stasis dispelling, removing the necrotic tissue and promoting granulation, without anaphylaxis, impel wound surface quickly-healing, and preparation is simple, with low cost, be applicable to skin ulcer, be especially applicable to the gangrene treatment of diabetic foot, significantly reduce the amputation rate of patient.
The Chinese medicine compound externally used coating liquid for the treatment of diabetic foot ulcer of the present invention, it is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: back flower skin ulcer 18-22g, Herba Pteridis Semipinnatae 18-22g, great Ye Camphor tree 10-14g, Herba Ceropegiae Christensenianae 10-14g, fourth Radix Raphani 10-14g, Helwingia himalaica 18-22g, Flos Carthami 10-14g, Radix Et Rhizoma Rhei 18-22g, Radix Salicis Hypoleucae 18-22g, Pilea lomatogramma Hand.-Mazz 13-17g, fine and soft careless 13-17g, ring tree 13-17g, Herba Cissampelotis pareiae 10-14g, Herba Circaeae Cordatae 10-14g, Radix seu Cortex Linderae Caudatae 10-14g and mild toxicity taro 10-14g.
As preferably, prepare by following parts by weight:
Back flower skin ulcer 20g, Herba Pteridis Semipinnatae 20g, great Ye Camphor tree 12g, Herba Ceropegiae Christensenianae 12g, fourth Radix Raphani 10-14g, Helwingia himalaica 20g, Flos Carthami 12g, Radix Et Rhizoma Rhei 20g, Radix Salicis Hypoleucae 20g, Pilea lomatogramma Hand.-Mazz 15g, fine and soft careless 15g, ring tree 15g, Herba Cissampelotis pareiae 12g, Herba Circaeae Cordatae 12g, Radix seu Cortex Linderae Caudatae 12g and mild toxicity taro 12g.
Chinese medicine of the present invention, obtain as follows: take back flower skin ulcer 18-22g, Herba Pteridis Semipinnatae 18-22g, great Ye Camphor tree 10-14g, Herba Ceropegiae Christensenianae 10-14g, fourth Radix Raphani 10-14g, Helwingia himalaica 18-22g, Flos Carthami 10-14g, Radix Et Rhizoma Rhei 18-22g, Radix Salicis Hypoleucae 18-22g, Pilea lomatogramma Hand.-Mazz 13-17g, fine and soft careless 13-17g, ring tree 13-17g, Herba Cissampelotis pareiae 10-14g, Herba Circaeae Cordatae 10-14g, Radix seu Cortex Linderae Caudatae 10-14g and mild toxicity taro 10-14g, add the water of 3 times amount, soak 3 hours, insert in jacketed pan, be heated to the boiling of outer gallbladder water, occasional agitation Chinese medicine, continue heating 2 hours, filter decocting liquid, add antiseptic to stir, leave standstill and cool, fill both obtained.
Pharmacology analysis: in side, back flower skin ulcer, Herba Pteridis Semipinnatae, great Ye Camphor tree, Herba Ceropegiae Christensenianae and fourth Radix Raphani are heat and toxic materials clearing away medicine; Helwingia himalaica, Flos Carthami, Radix Et Rhizoma Rhei and Radix Salicis Hypoleucae are blood circulation promoting and blood stasis dispelling; Pilea lomatogramma Hand.-Mazz, fine and soft grass, ring tree, Herba Cissampelotis pareiae, Herba Circaeae Cordatae, Radix seu Cortex Linderae Caudatae and mild toxicity taro removing the necrotic tissue convergence granulation promoting.
All medicines share, and get final product heat-clearing and toxic substances removing, are beneficial to the infection of removing whole body and local, again can blood circulation promoting and blood stasis dispelling, improve blood flow state, remove the various injurious factors in blood, repair the tunica intima of damage, its blood supply is increased, thus improves microcirculation, impel granulation tissue newborn.Nerve is able to nutrition, is conducive to the recovery of nervous function damage, controls traumatic infection, and accelerate ulcer healing, the limb function protecting patient avoids amputation and disables.
Back flower skin ulcer: pungent; Light; Cool in nature, heat-clearing and toxic substances removing; To eliminate the phlegm blood stasis dispelling.Main lung-heat cough with asthma; Pulmonary tuberculosis chronic cough; Spitting of blood; Sore swollen toxin; Traumatic injury; Traumatic hemorrhage; Infantile malnutrition.
Herba Pteridis Semipinnatae: bitter, pungent, cool.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For bacillary dysentery, acute enteritis, icterohepatitis, conjunctivitis; Traumatic injury is controlled in external, traumatic hemorrhage, skin infection furuncle and phyma, eczema, venom.
Great Ye Camphor tree: pungent; Cool.Heat-clearing and toxic substances removing; Removing dampness to relieve itching.Main swollen ulcer drug; Eczema scabies.
Herba Ceropegiae Christensenianae: acid is flat.Heat-clearing and toxic substances removing; Main innominate toxic swelling.
Fourth Radix Raphani: bitter, cold.Slightly poisonous.Heat-clearing and toxic substances removing, expelling wind and activating blood circulation.For oral ulcer, laryngopharynx swelling and pain, chronic appendicitis, periappendicitis, abdominal pain due to blood stasis, leucorrhea; Mastitis are controlled in external, sore and toxic, venom, hemorrhoid.
Helwingia himalaica: bitter, micro-puckery, cool.Blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing.For traumatic injury, fracture, rheumatic arthritis, stomachache, dysentery, menoxenia; Burn and scald is controlled in external, furuncle carbuncle, venom.
Flos Carthami: sweet in the mouth is flat, nontoxic.Enter the heart, Liver Channel.Blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens.Control troubled thoughts pent-up, chest and diaphragm painful abdominal mass is vexed, and spit blood, typhoid fever is gone mad, and frightened fear in a trance, women's amenorrhea, postnatal blood stasis is suffered from abdominal pain, tumbling and swelling.
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature, nontoxic; Return spleen, stomach, large intestine, liver, pericardium channel; Purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood bleeder is had for heat in blood.
Radix Salicis Hypoleucae: pungent, puckery, temperature.Expelling wind and removing dampness, purify the blood blood stasis dispelling.Cure mainly rheumatic ostalgia, impairment caused by overstrain.Snake head-like infection is controlled in external.
Pilea lomatogramma Hand.-Mazz: sweet in the mouth; Bitter; Cold in nature.Stasis-dispelling and pain-killing; Removing toxic substances sore.Main traumatic injury; Empyrosis.
Fine and soft grass: bitter in the mouth; Property is put down.Expelling wind and removing dampness; Removing toxic substances sore.Main air pain of dampness syndrome; Laryngopharynx swelling and pain; Osteomyelitis; Skin eczema; Furuncle swelling toxin; Stubborn dermatitis.
Ceriop tagl (perr), c. B. Rob: removing toxic substances sore; Hemostasis.Main skin infection festers; Traumatic hemorrhage.
Ring is set: removing toxic substances sore.Main ulcer.
Herba Cissampelotis pareiae: sweet, bitter, temperature.Reducing swelling and alleviating pain, hemostasis, granulation promoting.Swell and ache for wound, wound hemorrhage.
Herba Circaeae Cordatae: bitter, cold.Slightly poisonous.Heat-clearing and toxic substances removing, granulation promoting.Scabies is controlled in external, abscess, knife injury.
Radix seu Cortex Linderae Caudatae: micro-sweet, acrid, warm.Hemostasia and promoting granulation, regulating QI to relieve pain.Control osteopatia sprain, wound congestive edema, hemorrhage, chest pain is coughed.
Mild toxicity taro: acrid in the mouth; Cold in nature; Poisonous.Hemostasia and promoting granulation; Removing toxic substances and promoting subsidence of swelling.Operator gunshot wound; Wound hemorrhage; Thromboangiitis; The sick furuncle and phyma of skin ulcer; Snake bite and insect sting.
Chinese medicine formula of the present invention, all medicine compatibilities, anti-inflammation and sterilization, the cell regeneration of affected tissue can be impelled, blood circulation promoting and blood stasis dispelling, removing the necrotic tissue and promoting granulation, without anaphylaxis, impel wound surface quickly-healing, and preparation is simple, with low cost, be applicable to skin ulcer, especially be applicable to the gangrene treatment of diabetic foot, significantly reduce the amputation rate of patient.
Efficacy assessment standard:
" diabetes (diabetes) traditional Chinese medical science dialectical and efficacy assessment standard by stages " that " the new Chinese medicine clinical guidance principle " issued according to Ministry of Public Health and diabetes Professional Committee of Chinese Chinese medicine association formulate is formulated.
Recovery from illness: clinical symptom disappearance, 0 phase patient skin coloration recovers normal, 1 phase above patient's skin ulcer face all healed;
Effective: clinical symptom disappearance, 0 phase patient skin recovers normal, 1 phase above patient's skin ulcer face more than 2/3 healing;
Effective: clinical symptoms takes a turn for the better, 0 phase patient skin coloration improves, 1 phase above patient's skin ulcer face more than 1/2 healing;
Invalid: all diseases are without improvement or increase the weight of.
Therapeutic outcome: diabetic foot ulcer patient 100 example, the coating liquid using medicine of the present invention to make coating, recovery from illness 62 example, accounts for 62%, and effective 17 examples, account for 17%, effective percentage is 79%.
Model case:
(1) Zheng, man, 56 years old, in May, 2014 went to a doctor.Because " find that blood glucose is high 10 years, right dorsal portion ulceration January, two little finger blackening are downright bad " is admitted to hospital.The nearly first visible 3.5X2.5CM in toe place in right instep shows fester, and skin surface kermesinus, ulcer surface has a small amount of slough and secretions.Red and swollen around ulcer, little finger blackening is downright bad, two pulsation of foot dorsal artery can, my institute gives that insulin blood sugar lowering is antibacterial waits Comprehensive Treatment, and additional Chinese medicinal formulae external application debridement is simultaneously changed dressings once-a-day, and skin ulcer face necrotic tissue cleaning, heals gradually; The bimester of continuing coating, the disappearance of all diseases is fully recovered.
(2) Tan, female, 65 years old, in June, 2014 went to a doctor, and more than 10 years of diabetes are suffered from readme, and long-term bed be can't take care of oneself.Vola portion occurs that 6X4CM ulcer surface is not healed for 1 year, breath malodor, every day 1-2 the sterilization debridement open sore part, apply this external application of Chinese medicine liquid, external application skin ulcer face with gauze leaching afterwards, after using January, abscess ulcer surface reduces, fresh granulation tissue is newborn, after continuing to apply April, and ulcer surface healing recovery from illness.
Detailed description of the invention
Embodiment 1
The Chinese medicine compound externally used coating liquid for the treatment of diabetic foot ulcer of the present invention, formed by the Chinese medicine proportioning of following parts by weight: back flower skin ulcer 20g, Herba Pteridis Semipinnatae 20g, great Ye Camphor tree 12g, Herba Ceropegiae Christensenianae 12g, fourth Radix Raphani 10-14g, Helwingia himalaica 20g, Flos Carthami 12g, Radix Et Rhizoma Rhei 20g, Radix Salicis Hypoleucae 20g, Pilea lomatogramma Hand.-Mazz 15g, fine and soft careless 15g, ring tree 15g, Herba Cissampelotis pareiae 12g, Herba Circaeae Cordatae 12g, Radix seu Cortex Linderae Caudatae 12g and mild toxicity taro 12g.
Chinese medicine formula of the present invention, prepare as follows and use:
Preparation method is carried out according to the following steps: take raw material of Chinese medicine according to the above ratio, adds the water of 3 times amount, soaks 3 hours, inserts in jacketed pan, be heated to the boiling of outer gallbladder water, occasional agitation Chinese medicine, continue heating 2 hours, filter decocting liquid, add antiseptic to stir, leave standstill and cool, fill both obtained.
Claims (2)
1. treat the Chinese medicine compound externally used coating liquid of diabetic foot ulcer for one kind, it is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: back flower skin ulcer 18-22g, Herba Pteridis Semipinnatae 18-22g, great Ye Camphor tree 10-14g, Herba Ceropegiae Christensenianae 10-14g, fourth Radix Raphani 10-14g, Helwingia himalaica 18-22g, Flos Carthami 10-14g, Radix Et Rhizoma Rhei 18-22g, Radix Salicis Hypoleucae 18-22g, Pilea lomatogramma Hand.-Mazz 13-17g, fine and soft careless 13-17g, ring tree 13-17g, Herba Cissampelotis pareiae 10-14g, Herba Circaeae Cordatae 10-14g, Radix seu Cortex Linderae Caudatae 10-14g and mild toxicity taro 10-14g.
2. the Chinese medicine compound externally used coating liquid for the treatment of diabetic foot ulcer according to claim 1, it is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: back flower skin ulcer 20g, Herba Pteridis Semipinnatae 20g, great Ye Camphor tree 12g, Herba Ceropegiae Christensenianae 12g, fourth Radix Raphani 10-14g, Helwingia himalaica 20g, Flos Carthami 12g, Radix Et Rhizoma Rhei 20g, Radix Salicis Hypoleucae 20g, Pilea lomatogramma Hand.-Mazz 15g, fine and soft careless 15g, ring tree 15g, Herba Cissampelotis pareiae 12g, Herba Circaeae Cordatae 12g, Radix seu Cortex Linderae Caudatae 12g and mild toxicity taro 12g.
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CN105920281A (en) * | 2016-06-20 | 2016-09-07 | 宋梅 | Traditional Chinese medicine for treating blood stasis vessel obstruction syndrome diabetic foot and preparation method thereof |
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CN103656372A (en) * | 2013-10-07 | 2014-03-26 | 刘景文 | Diabetic foot ointment |
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CN103656372A (en) * | 2013-10-07 | 2014-03-26 | 刘景文 | Diabetic foot ointment |
Cited By (1)
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CN105920281A (en) * | 2016-06-20 | 2016-09-07 | 宋梅 | Traditional Chinese medicine for treating blood stasis vessel obstruction syndrome diabetic foot and preparation method thereof |
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Application publication date: 20150812 |