CN113491732A - Granulation promoting and wound healing Chinese herbal medicine external ointment for treating pyocutaneous disease wounds - Google Patents

Granulation promoting and wound healing Chinese herbal medicine external ointment for treating pyocutaneous disease wounds Download PDF

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CN113491732A
CN113491732A CN202110707187.9A CN202110707187A CN113491732A CN 113491732 A CN113491732 A CN 113491732A CN 202110707187 A CN202110707187 A CN 202110707187A CN 113491732 A CN113491732 A CN 113491732A
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萧全顺
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Abstract

The invention relates to a tissue regeneration promoting and wound healing Chinese herbal medicine external ointment for treating pyogenic skin wounds, which is a tissue regeneration promoting and wound healing Chinese herbal medicine external ointment for treating pyogenic skin wounds, completely draining pus and not healing pyogenic skin wounds at sores, and is a new innovation in the technical field of Chinese herbal medicine external medicines for treating pyogenic skin wounds, stopping bleeding and relieving pain and diminishing swelling and promoting tissue regeneration in the field of traditional Chinese medicine, the invention adopts the psychological characteristics of safety with skin, no stimulation and no allergy, which are in accordance with the pain of patients fearing to operate, and also avoids the defect that western medicine antibiotics are orally taken for a long time to aggravate the burden of liver and kidney, therefore, the Chinese herbal medicine has definite therapeutic action on pyocutaneous wounds, and the diseases such as pyocutaneous wounds, diabetic foot, vasculitis ulcer, bedsore and the like, wound disunion, sore erosion and the like are common diseases clinically at present, and the Chinese herbal medicine has the remarkable advantages of multi-component and multi-effect, no side effect, no pain and the like, and is recorded by history [ external treatment medicine ]: the external treatment, i.e. the internal treatment, and the external treatment, i.e. the internal medicine, lay a solid theoretical foundation for the development of external Chinese herbal medicines.

Description

Granulation promoting and wound healing Chinese herbal medicine external ointment for treating pyocutaneous disease wounds
A topical Chinese medicinal ointment for treating pyocutaneous disease, wound with ulcerated pyocutaneous disease, wound with pus, and granulation promoting and wound healing effects
The technical field is as follows:
the invention relates to a Chinese herbal medicine external ointment, in particular to a tissue regeneration promoting and wound healing Chinese herbal medicine external ointment for treating pyogenic skin wounds with ulcerated sores, exhausted pus and unretracted sores, which is a new innovation in the technical field of external medicines for treating pyogenic skin wounds by Chinese herbal medicines in the field of traditional Chinese medicine,
background art:
the traditional Chinese medicine is a cultural product which inherits Chinese nation for 5000 years, and is also an important clinical subject in the medical field, the current symptoms of pyogenic diseases such as diabetic foot, vasculitis ulcer, bedsore and the like, bleeding, pain, edema, wound disunion, sore erosion and the like of an open incision operation are common diseases in the current society, and are also common clinical symptoms, patients are often in the spirits of anxiety, mental stress and emotional anxiety, the disease condition is worsened day by day, the research on external medicines for stopping bleeding, relieving pain, diminishing swelling, promoting tissue regeneration, removing putrefaction and expelling pus in traditional Chinese medicine or western medicine for many years has many defects, according to clinical practice and relevant data research, the current antibiotic medicines for treating the pyogenic diseases such as pyogenic diseases and wounds in human surgery have the disadvantages of high manufacturing cost, insignificant treatment effect, damage to liver and kidney, large stimulation side effect on gastrointestinal tract and the like, at present, the western medicine clinical treatment generally adopts amputation operation, the pain greatly damages primordial qi, the postoperative mortality is higher, the patient is not easy to accept, the treatment scheme can not meet the clinical treatment requirement of the wound at present, the Chinese herbal medicine has the comprehensive effect of multiple components and multiple effects, the characteristics pay attention to the comprehensive synergistic effect in the body tissue, no side effect is caused, particularly, the Chinese herbal medicine external application for treating the wound has the obvious advantages of convenient use, obvious curative effect, liver and kidney tonifying, no pain and the like, and the history records [ external treatment medicine ]: the consistency of external treatment and internal treatment in the aspects of etiology, pathogenesis, dialectical medication and the like is emphasized, and a solid theoretical basis is laid for the development of Chinese herbal medicine external application, so that the active development and research of the Chinese herbal medicine external application for removing the necrotic tissue and expelling pus in the wound of the sore and ulcer has important social significance,
the invention content is as follows:
aiming at the problems, the invention provides a tissue regeneration promoting and wound healing Chinese herbal medicine external ointment for treating pyogenic skin wounds in order to solve the clinical needs of the medical field at present, and the invention adopts the following technical scheme to achieve the aim, and the tissue regeneration promoting and wound healing Chinese herbal medicine external ointment for treating the pyogenic skin wounds is characterized by being prepared by grinding the following Chinese herbal medicine raw materials and auxiliary materials in parts by weight: 25 to 35 parts of trichosanthes root, 25 to 35 parts of raw rhubarb, 25 to 35 parts of scutellaria baicalensis, 25 to 35 parts of phellodendron, 25 to 35 parts of raw gardenia, 5 to 15 parts of garden burnet, 5 to 15 parts of cortex lycii radicis, 25 to 35 parts of raw liquorice, 25 to 35 parts of phaseolus calcaratus, 5 to 15 parts of angelica dahurica, 25 to 35 parts of coptis chinensis, 5 to 15 parts of astragalus mongholicus and 20 to 30 parts of sesame oil serving as auxiliary materials, 30 to 40 parts of medical vaseline and 10 to 20 parts of honey are ground into fine powder and evenly stirred to prepare paste,
Detailed Description
The invention can prepare the tissue regeneration promoting and wound healing Chinese herbal medicine external ointment suitable for clinical pyocutaneous wounds by adopting the following technical scheme and adding auxiliary materials according to the following Chinese herbal medicine raw materials in parts by weight: 30 parts of trichosanthes root, 30 parts of raw rhubarb, 30 parts of scutellaria baicalensis, 30 parts of phellodendron bark, 30 parts of raw gardenia, 10 parts of garden burnet, 10 parts of cortex lycii radicis, 30 parts of raw liquorice, 30 parts of phaseolus calcaratus, 10 parts of angelica dahurica, 30 parts of coptis chinensis, 10 parts of astragalus mongholicus and auxiliary materials of 25 parts of sesame oil, 35 parts of medical vaseline and 15 parts of honey, grinding into fine powder, uniformly stirring to prepare paste,
the preparation method comprises the following steps: according to the requirements of diseases, the mixed Chinese herbal medicine raw materials which are ground into fine powder are placed into a sterilized container, auxiliary materials of sesame oil, medical vaseline and honey according to the specified weight percentage are added into the container, the mixture is slowly stirred in the container until the mixture is fully and uniformly formed into a paste, Chinese herbal medicine external ointment is prepared, the wound surface is cleaned by hydrogen peroxide, the wound surface is cleaned by iodophor, then the physiological saline is used for deiodination, the powder of the product is spread or spread on a sterilized gauze, the sterilized gauze is applied to cover the wound surface, the wound surface is wrapped up, the medicine is changed once a day,
the pharmacological action of the Chinese herbal medicine raw materials:
trichosanthes root: the history records [ Rihuazi materia Medica ]: trichosanthes root, radix trichosanthis has the effects of expelling pus, removing toxic swelling, promoting granulation and promoting granulation, and eliminating blood stasis, which is recorded in the records of the Western medicine of Zhongzhao Zhong: trichosanthis radix, radix Trichosanthis, radix astragali and radix Glycyrrhizae (all should be used for raw materials) are used together to relieve heat-toxin in all sores and ulcers, and to promote tissue regeneration and discharge pus, i.e. when the sores are deep and the other parts are not applied, pus can be discharged slowly from the muscles growing in the body.
Raw rhubarb:damp-heat(ii) a Purging fire;cooling blood(ii) a Removing blood stasis and stopping bleeding; the efficacy of clearing away heat and toxic material,
scutellaria baicalensis: can be used for treating fever due to damp-warm pathogen, chest distress, thirst without desire for drink, damp-heat dysentery, jaundice, etc., and has effects of clearing heat and eliminating dampness.
Phellodendron bark: damp-heat dysentery, diarrhea, jaundice; nocturnal emission, stranguria with turbid urine, leukorrhagia; bone-steaming, fatigue-heat, night sweat; andaphtha of the mouth and tongue(ii) a Conjunctival congestion with swelling and pain; carbuncle, deep-rooted carbuncle and sore; skin eczema \
Raw gardenia: clear heat, purge fire, cool blood. For restlessness and insomnia due to deficiency of heat, jaundice,gonorrhea with difficultyDiabetes, conjunctival congestion, pharyngalgia, hematemesis, epistaxis, bloody flux, hematuria, sores and ulcers due to heat-toxin, sprain and swelling pain. The records of the Guangzhou army 'handbook of commonly used Chinese herbal medicines': to clear heat and remove toxicity, cool blood and purge fire. Medicine for curing diabetesIcteric hepatitisBroad bean yellow, cold with high fever,bacillary dysenteryNephritis, edema, epistaxis, aphtha, mastitis, sores and ulcers, and pyogenic infections. ", a
Garden burnet root: cold in nature, bitter in acid and non-toxic; it enters liver, lung, kidney and large intestine meridians. Has the effects of cooling blood, stopping bleeding, clearing away heat and toxic materials, nourishing yin, relieving swelling and healing wound. The history records "this Jing Chang Shu" (continuous Dredging of the book): sang Yu is not suitable for different kinds of leukorrhagia and not suitable for pain of seven kinds of leukorrhagia, but it is also called pain-relieving for seven kinds of leukorrhagia, . What is the case is that blood and qi are removed and dispersed, wind enters the deficiency and becomes malignant meat, wind enters the ying-wei and swells into sweat, and incised wound is attacked by wind and is not painful convalesce, which are not all the Ye belonging to sanguisorba? For stopping pus and blood, atrophy, sores, heat sores and postpartum internal obstruction, it is known as jin Jiang Gao from Bie Lu (entry book). To eliminate alcohol, remove thirst and tonify wound. It is different from other things in meaning, but it is still the root of the violation of blood-deficiency qi and the disturbance of wind-qi in the course of the violation of qi and blood, and it is the disease that the treatment uses the wind-transforming qi as the raw gas, so that qi and blood harmonize the son and come into .
Cortex lycii radicis: clear heat and cool blood. For consumptive diseaseTidal fever and night sweatLung heatCough and asthma, hematemesis, epistaxis, stranguria with blood,diabetesHypertension, carbuncle and swelling, malignant boil.
Raw licorice root: mainly has the functions of tonifying qi and spleen, eliminating phlegm and stopping cough, relieving spasm and pain, clearing away heat and toxic materials, harmonizing drug property, tonifying qi and spleen
Small red beans: induce diuresis to alleviate edema, remove toxicity and expel pus. Can be used for treating edema, tinea pedis, edema, jaundice, dark urine, rheumatism, pyretic arthralgia, carbuncle, suppurative sore, intestinal carbuncle, and abdominal pain. [ solution ] AShennong herbal channelIt is indicated for edema and muscular distension because it can relieve heat, toxicity, abscess and swelling, disperse blood stasis and treat restlessness.
Radix angelicae: the history records "compendium" of dahurian angelica root: white, pungent taste, and good effect in improving hand function; warmth in nature and thick qi, sufficient yang-yin to clear up; fragrant, ascending and entering the lung meridian of Taiyin. Wind-heat in the three meridians; for example, the damp-heat in the three meridians can also cause diseases such as fistula, leukorrhagia, and superficial infection; wind-heat is pungent in property and damp-heat is warm in nature. It is a main herb of yangming, so it can also be used for treating blood disease, fetal disease, promoting pus discharge, promoting granulation and relieving pain. Regurgitation and vomiting; relieve arsenic toxicity, snake bite and incised wound. Dahurian angelica root in Rihuazi materia Medica: for red eye, pterygium, persistent blood, new blood, mammary abscess, hair and back, scrofula, intestinal wind, hemorrhoid and fistula, pus discharge, cellulitis, scabies, pain relieving and granulation promoting.
Coptis chinensis: [ solution ] AEndowing medicine propertyA large section of: bitter and mild taste, cold smell and no toxicity. Sinking also in yin. The usage is four: purging heart fire, relieving stuffiness and fullness in the lower abdomen; governing the intestine to remove mixed red in the intestine; it is indicated for eye diseases and sudden eruption, and for sores and ulcers, both in the beginning and in the end. The book of drug property resolution: huang Lian is bitter in taste, cold in nature, non-toxic and enters heart meridian. Mainly treating heart fire inflammation, eye diseases, red swelling of sores and ulcers, intestinal red diarrhea, stuffiness and fullness, diarrhea, infantile malnutrition heat, aphtha in the middle-jiao, palpitation and dysphoria, and heat syndrome in the daytime.
Astragalus root: the sore and ulcer can not heal for a long time, and has the functions of promoting tissue regeneration and healing wound, and it can enhance the immunity of the body
The Chinese herbal medicine raw materials are added with medical auxiliary materials to prepare the granulation promoting and wound healing Chinese herbal medicine external ointment suitable for treating pyocutaneous wounds clinically, and the preparation method of the Chinese herbal medicine external ointment comprises the following steps:
the method comprises the following steps: weighing the above Chinese medicinal materials according to a specified weight ratio, grinding into fine powder for use,
step two: putting the mixed Chinese herbal medicine ground into fine powder into a container, adding the sesame oil, the medical vaseline and the honey according to the specified weight percentage,
step three: slowly stirring the above mixed Chinese herbal medicines and adjuvants in a container to obtain paste, making into Chinese herbal medicine topical unguent,
the Chinese herbal medicine external ointment of the invention adopts pharmaceutic adjuvant with good biocompatibility with skin, is safe, non-irritant and non-allergic, meets the psychological characteristics of patients fearing great operation pain, and also avoids the stimulation of western medicine antibiotics orally taken for a long time to gastrointestinal tracts and the defect of aggravating liver and kidney burden, therefore, the invention has exact treatment effect on ulcer wounds with ulcerated sores, exhausted pus and no sore wound, and the invention further explains the Chinese herbal medicine external ointment of the invention from clinical application results that has obvious beneficial effect and curative effect,
clinical patient data:
68 patients are randomly collected for many years, and the age of the patients is 54 to 72 years, which accords with the clinical diagnosis standard of traditional Chinese medicine (the clinical research guiding principle of new traditional Chinese medicine):
1 diabetic foot: the patients suffer from diabetes with high blood sugar for a long time for many years, the diabetes is caused to recur, the diabetic feet appear, pyocutaneous wounds appear under the feet, the soles of the feet are in the early stage shown as edema and purple, the activity is limited, the abscesses and putrefaction are generated under the feet in the later stage, the wound surface erosion, pyocutaneous open wounds, the pain is difficult to endure, the depth is 0.3cm to 2cm, the individual wounds are septicemic, the muscles and bones,
2, a medication method: cleaning the wound surface with hydrogen peroxide, cleaning the wound surface with iodophor, deiodinating with normal saline (according to the recovery condition of disease, it is not necessary to use hydrogen peroxide and iodophor, and can directly use normal saline to clean the wound surface), smearing products or smearing the product on sterilized gauze, covering the wound surface, wrapping with sterilized gauze, changing medicines once every day, changing medicines every other day after one week, and changing medicines every 30 days as a course of treatment, wherein the disease is contraindicated for wine, spicy food, aquatic product, beef and mutton food, and needs western medicines for reducing blood sugar, so as to achieve the substantially normal curative effect of blood sugar value in fasting state and two hours after treatment,
3 treatment results: the clinical treatment is completely controlled after one course of treatment, 15 cases are clinically controlled after two courses of treatment, 35 cases are clinically effective, 15 cases are clinically significant, 3 cases are clinically ineffective (because the blood sugar can not be controlled), 15 cases are clinically controlled after three courses of treatment, 30 cases are clinically effective, 20 cases are clinically significant, 3 cases are clinically ineffective, and all patients do not have adverse reactions such as skin irritation, allergy and the like in the treatment process,
second, 60 patients were randomly collected for many years, and the patients aged 60 to 78 years all meet the clinical diagnosis standard of traditional Chinese medicine (guiding principle of clinical research of new traditional Chinese medicine):
1, bedsore: when a patient lies in bed for a long time, the pressed part of the body causes a plurality of sores and ulcers, the pressed part at the initial stage shows red purple, the pressed part at the middle stage shows bluish purple, the pressed part at the later stage produces abscess and putrefaction, the wound surface erosion, a plurality of open wounds of the sores and the ulcers, the depth of the open wounds is different from 0.5cm to 2.5cm, and individual wounds septicemia bone and muscle,
2, a medication method: cleaning wound surface with hydrogen peroxide, cleaning wound surface with iodophor, removing iodine with normal saline (hydrogen peroxide and iodophor are not used according to disease recovery condition, and normal saline can be directly used for cleaning wound surface), smearing product or smearing the product on sterile gauze, covering wound surface, wrapping with sterile gauze, changing medicine once every day, changing medicine every other day after one week, and taking 30 days as a course of treatment, wherein the disease needs avoiding drinking wine, pungent food, and aquatic product such as beef and mutton food
3 treatment results: after treatment of one course, the clinical effect is totally controlled, after treatment of two courses, 20 cases are clinically controlled, 25 cases are clinically effective, 13 cases are clinically effective, 2 cases are clinically ineffective, 15 cases are clinically controlled after treatment of three courses, 30 cases are clinically effective, 19 cases are clinically effective, 1 case is clinically ineffective, and all patients have no adverse reactions such as skin irritation, allergy and the like in the treatment process,
55 patients are randomly collected for many years, and the age of the patients is 55 to 70 years, which accords with the clinical diagnosis standard of traditional Chinese medicine (the clinical research guiding principle of new traditional Chinese medicine):
1. vasculitis and ulcer: vasculitis ulcer refers to the later stage symptom caused by obstruction of artery and vein, the symptoms of early stage vasculitis are various, such as thromboangiitis obliterans, arteriosclerosis and the like, if vasculitis ulcer occurs, the later stage symptom is more serious, and the symptoms are manifested by open wound of pyocutaneous disease on the lower leg, abscess putrefaction, erosion, pain and limited action of wound surface,
2, a medication method: cleaning the wound surface with hydrogen peroxide, cleaning the wound surface with iodophor, deiodinating with normal saline (according to the recovery condition of disease, it is not necessary to use hydrogen peroxide and iodophor, and can directly use normal saline to clean the wound surface), smearing products or smearing the product on a sterilized gauze, covering the wound surface, wrapping with the sterilized gauze, changing the medicine once every day, changing the medicine every other day after one week, and changing the medicine every other day for 30 days as a course of treatment, wherein the disease is firstly treated by absolute smoking prohibition and wine prohibition, spicy food prohibition and aquatic product food, and if the main pathological change is arterial obstruction of the limbs, the principle is that western medicine is needed to improve the circulation of the blood of the limbs, the curative effect is optimal,
3 treatment results: after treatment of one course, clinical control is carried out completely, after treatment of two courses, the clinical control is carried out for 12 cases, the clinical control is carried out for 25 cases, the clinical effect is 15 cases, the clinical effect is 3 cases (the circulation curative effect of limb blood is not improved due to western medicines), after treatment of three courses, the clinical control is carried out for 10 cases, the clinical effect is 27 cases, the clinical effect is 15 cases, the clinical effect is 3 cases, and adverse reactions such as skin irritation, allergy and the like do not occur in the treatment process of all patients.

Claims (1)

1. Aiming at the problems, the invention provides a tissue regeneration promoting and wound healing Chinese herbal medicine external ointment for treating pyogenic skin wounds in order to solve the clinical needs of the medical field at present, and the invention adopts the following technical scheme to achieve the aim, and the tissue regeneration promoting and wound healing Chinese herbal medicine external ointment for treating the pyogenic skin wounds is characterized by being prepared by grinding the following Chinese herbal medicine raw materials and auxiliary materials in parts by weight: 25 to 35 parts of trichosanthes root, 25 to 35 parts of raw rhubarb, 25 to 35 parts of scutellaria baicalensis, 25 to 35 parts of phellodendron, 25 to 35 parts of raw gardenia, 5 to 15 parts of garden burnet, 5 to 15 parts of cortex lycii radicis, 25 to 35 parts of raw liquorice, 25 to 35 parts of phaseolus calcaratus, 5 to 15 parts of angelica dahurica, 25 to 35 parts of coptis chinensis, 5 to 15 parts of astragalus mongholicus and 20 to 30 parts of sesame oil serving as an auxiliary material, 30 to 40 parts of medical vaseline and 10 to 20 parts of honey are ground into fine powder and evenly stirred to prepare paste.
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114533859A (en) * 2022-02-23 2022-05-27 宁波项谨记百货有限公司 Traditional Chinese medicine ointment for treating haemorrhoids and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN101406557A (en) * 2008-11-28 2009-04-15 吕晓霞 External-use Chinese medicine for treating burn, scald and various skin injuries

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CN101406557A (en) * 2008-11-28 2009-04-15 吕晓霞 External-use Chinese medicine for treating burn, scald and various skin injuries

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杜建波等: "栀黄止痛散对皮肤刺激性及致敏性的实验研究", 《中医学报》 *

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* Cited by examiner, † Cited by third party
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CN114533859A (en) * 2022-02-23 2022-05-27 宁波项谨记百货有限公司 Traditional Chinese medicine ointment for treating haemorrhoids and preparation method thereof

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