CN105250685A - Traditional Chinese medicine composition for treating burns and preparation method of traditional Chinese medicine composition - Google Patents

Abstract

A traditional Chinese medicine composition for treating burns, consisting of Codonopsis pilosula, Acanthopanax, Usnea, Digupi, Jiaogulan, Astragalus, Scutellaria baicalensis, golden buckwheat, Daxueteng, Polygonum cuspidatum, safflower, raw Burnet, Atractylodes macrocephala, and arborvitae Composition of leaves, asparagus, dried blood, andrographis paniculata, agrimony, white-backed leaves, bletilla striata, golden fruit olive, aloe vera, borneol, ebony, diffusa, field seven, peach kernels, cinnamon sticks, akebia and honey. The traditional Chinese medicine composition is composed of multiple components, low cost, non-toxic and side effects, safe and effective, suitable for patients with various areas and deep burns, rapid pain relief, anti-infection, fast healing, promotes rapid wound repair, and can effectively prevent the formation of skin scars .

Description

A kind of traditional Chinese medicine composition for treating burns and preparation method thereof

technical field

The invention belongs to the technical field of medicine and relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating burns.

Background technique

Burns are an unexpected disease caused by various factors such as heat, steam, flame, electric current, laser, radiation, acid, alkali, phosphorus, etc. Usually so-called burns refer to thermal burns caused by high temperature alone, which are common in clinical practice, especially small and medium area burns occur frequently in daily life. According to the calculations of relevant authoritative departments, about 10,000 people out of a million people in my country are accidentally burned every year, and there are about 13 million people in the country, of which 6.3 million people need hospitalization, and the trend is gradually increasing every year. Due to problems such as wound pain, progressive necrosis, susceptibility to infection, and difficulty in scar healing in burn treatment, it has brought certain difficulties to its treatment, resulting in mental distress for patients and increasing the cost of treatment for patients.

Burn is a clinical common disease and frequently-occurring disease. Because of the unbearable pain it causes to patients, the susceptibility of burn wound and the series of physiological and pathological changes and serious consequences brought by infection to the patient's body, it has always troubled the medical industry. boundary. At present, clinically, the medicines for external treatment of burns are mainly traditional Chinese medicine preparations and western medicine preparations. Chinese medicine preparations are almost all plasters with oil as the matrix. Due to the nature of the oil, the matrix is greasy and hydrophobic. When using it, one is that the matrix does not absorb water, and the other is Oil clogs the sebaceous glands, and the treatment of erosive wounds with a large amount of exudate is not effective, and it also creates conditions for infection, and even causes the exudate to seep back into the affected area and aggravate the condition.

Existing burn medicine for external use, although obtain certain curative effect in the treatment of I degree, superficial II degree burn, aspect the timeliness and recovery time of alleviating burn pain are not very satisfactory yet, have oozing out to burn wound surface, especially deep burn. The curative effect is worse for burns above II degree and untimely or improperly treated burns causing infection.

Children under the age of 6 and the elderly are vulnerable to burns. Children are full of curiosity about the surrounding environment and have a strong desire to touch things, so they are extremely vulnerable, such as burns caused by playing with fire or scalded by bathing due to lack of effective protection measures for electrical appliances. With the aging of the social population, the elderly population in my country is increasing year by year, and the burn and scald problems of the elderly have attracted the attention of the burn department. Burns and scalds in the elderly are mainly caused by accidents in daily life. The elderly are slow in action and unresponsive, which leads to dodge when burns and scalds occur, and the rescue is not timely. At the same time, due to the changes in the physiological anatomy of the skin of the elderly, once a burn occurs, the wound is deep, the reaction is severe, and the course of the disease is long. Treatment is complicated by the variety of diseases that a person already has. With the development of various technologies, the development speed of smelting industry, petroleum industry, chemical industry, electric power industry, transportation, etc. has accelerated correspondingly, and the chances of accidents have also increased, such as boiler explosions, oil depot fires, and plane crashes. In recent years, entertainment venues have also become areas where burn accidents frequently occur, and often cause mass deaths and injuries, with extremely serious consequences. Burns and scalds are different from other diseases. What they bring to patients is not only physical trauma, but more importantly, mental and psychological damage. Disability due to burns and loss of working ability, self-care ability or disfigurement are quite common. Many patients become a burden to the society and family due to disability after recovery, and dare not go to the society because of disfigurement. Some of them committed suicide because they couldn't bear the consequences, which became one of the social problems that need social attention. Burns and scalds often bring unbearable pain to patients. Usually the most effective method is supplemented with anesthetics such as tetracaine and lidocaine to relieve pain, but it can also cause severe side effects such as nausea, vomiting, and diarrhea in patients. aggravated the pain of the patient.

Most people believe that heat is the only cause of burns, however, certain chemicals and electrical currents can also cause burns. The skin is often only part of the body when burned, the subcutaneous tissue may also be burned, and even internal organ burns may occur when there is no skin burn. For example, drinking very hot liquid or corrosive substances (such as acid, etc.) can burn the esophagus and stomach. In a building fire, inhalation of smoke or hot air may cause lung burns. Burned tissue may die. When tissue is burned, fluid in blood vessels seeps out, causing tissue edema. When a large area is burned, the permeability of the blood vessels is abnormal, and a large amount of fluid is lost, which may cause shock. In shock, blood pressure is low and blood flow to the brain and other vital organs is reduced. Electric burns are caused by high temperatures above 5000°C when electric current flows through the body, sometimes called arc burns. The skin is often completely destroyed and charred where the current enters the body. Because the skin resistance in contact with the charged body is very high, a large amount of electric energy is converted into heat there to burn the surface. Most electrical burns also severely damage the underlying tissue, and burns vary in extent and depth. The area of effect may be much larger than the area of the burned skin. Severe electrical shock can cause apnea, arrhythmia, and dangerous heart rhythm disturbances. Chemical burns can be caused by a variety of irritating and toxic chemicals, including strong acids, strong bases, phenol, toluene (organic solvents), mustard gas, phosphorus, and more. Chemical burns can cause tissue necrosis that slowly expands for hours after the burn.

The severity of burn depends on the extent and depth of injured tissue, and the degree of burn can be divided into I degree, II degree and III degree. I degree burn injury is the lightest. Burned skin was red, painful, tender, exuded or edematous. When the injured part is lightly pressed, it turns white locally, but there are no blisters. Second degree burn injury is deeper. Skin blisters. The bottom of the blister is red or white and filled with a clear, viscous fluid. Sensitive to touch, turns white when pressed. III degree burn injury is the deepest. The burned surface can be whitish, softened, or black, charred and leathery. Often mistaken for normal skin in fair-skinned people due to burnt skin becoming pale, but no longer discolored when pressed. The erythrocyte that destroys can make burn local skin to be cerise, has once in a while vesicle, and the hair in burn area is easy to pull out, and feels to go down. III degree burn area generally has no pain sensation. Because the nerve endings in the skin are damaged. Often will be through several days after burn, could distinguish deep II degree and III degree burn. Burn healing depends on the depth and location of the burn. In superficial burns (first-degree or superficial second-degree burns), the necrotic skin is sloughed off, and the epidermis re-grows to cover the underlying layer, with little or no scarring. These burns do not damage the deep dermis of the skin. The dermis cannot regenerate. If the wound is very small (not larger than a coin), as long as it is kept clean, even a deep burn may heal itself. If the underlying dermis is extensively damaged, a skin graft is often required. Healthy skin grafts for skin grafting can be taken from the unburned part of the burn patient (autologous skin grafting), or from other living people or corpses (allogeneic skin grafting) or other types of animals (xenografting). Pig skin is commonly used because It is very similar to human skin. Autologous skin grafting is permanent, while skin grafting from other people or animals is temporary. It is a measure taken to protect the wound during the wound healing process, and it will be rejected by the body after 10 to 14 days. During the burn healing period, the patient consumes more calories and nutrients. People who have difficulty eating can drink nutrient solution or be fed with a nasogastric tube. Severe burns take a long time to heal, sometimes years, and patients can become very depressed as a result. Most burn centers provide psychological support to such patients through social workers, psychiatrists and others.

Traditional Chinese medicine believes that burns are caused by strong heat acting on the human body, heat toxins invade, qi and blood stagnation, skin and flesh rot in mild cases, flaming heat and toxins in severe cases, hurting Yin fluid in the body, or heat toxins attack viscera internally, resulting in disharmony of viscera , Yin and Yang imbalance. Its clinical symptoms can be divided into fire-heat injuring body fluid, yin injuring yang, prolapse of fire-toxin, deficiency of both qi and blood, weakness of spleen and stomach. The Qi and blood deficiency type: low-grade or no fever, fatigue, loss of appetite, emaciated body, pale complexion, pale granulation on the wound surface, difficult to heal; pale tongue, thin white fur, thready and weak pulse.

Western medicine treatment of burns mostly adopts antibiotic ointment or ointment, and intravenous antibiotics. Antibiotics may help prevent infection, but long-term use of antibiotics will not only cause drug resistance, but also cause more toxic and side effects, and when the quality and quantity of human immunoglobulins are insufficient, cellular immune function is low, or the performance and quality of phagocytic cells When it is insufficient, antibiotic treatment is difficult to be effective.

Contents of the invention

The object of the present invention is to provide a traditional Chinese medicine composition for treating burns, which is composed of multiple components, has low cost, no toxic and side effects, is safe and effective, is applicable to patients with various areas and deep burns, and can relieve pain quickly. Anti-infection, fast healing, promote rapid wound repair, can effectively prevent the formation of skin scars.

Above-mentioned purpose of the present invention is achieved by following technical scheme:

A traditional Chinese medicine composition for treating burns, the raw materials of which are composed of Codonopsis pilosula, Acanthopanax, Usnea, Digupi, Gynostemma pentaphyllum, Astragalus, Scutellaria baicalensis, golden buckwheat, Sacred vine, Polygonum cuspidatum, Safflower , Raw Burnet, Atractylodes macrocephala, Arborvitae leaf, Asparagus, Dracaena, Andrographis paniculata, Agrimony, White back leaf, Bletilla striata, Golden fruit olive, Aloe vera, Borneol, Black plum, Hedyotis diffusa, Tianqi, peach kernel, Guizhi, Composition of akebia and honey.

Further, the composition and parts by weight of raw materials for making the traditional Chinese medicine composition are: Codonopsis 9-13 parts, Acanthopanax 2-4 parts, Usnea 6-8 parts, Digupi 20-30 parts, Gynostemma 16 parts -25 parts, 4-7 parts of Astragalus, 12-18 parts of Scutellaria baicalensis, 5-12 parts of golden buckwheat, 3-5 parts of Sargassum vine, 13-20 parts of knotweed, 16-30 parts of safflower, 30-50 parts of raw Burnet , 15-20 parts of Atractylodes macrocephala, 9-14 parts of arborvitae leaves, 10-15 parts of asparagus, 6-10 parts of blood, 22-30 parts of Andrographis paniculata, 7-10 parts of Agrimony, 4-8 parts of white back leaves, 5-8 parts of bletilla striata, 8-13 parts of golden fruit olive, 13-20 parts of aloe vera, 17-30 parts of borneol, 14-27 parts of black plum, 5-11 parts of Hedyotis diffusa, 8-12 parts of Tianqi, 19 parts of peach kernel -30 parts, 14-25 parts of cassia twig, 6-12 parts of akebia, 10-20 parts of honey.

Further, the composition and parts by weight of raw materials for making the traditional Chinese medicine composition are: 9 parts of Codonopsis pilosula, 2 parts of Acanthopanax, 8 parts of Usnea, 25 parts of Digupi, 20 parts of Jiaogulan, 4 parts of Astragalus, 16 parts of Scutellaria baicalensis 10 parts of golden buckwheat, 4 parts of Daxue vine, 20 parts of Polygonum cuspidatum, 28 parts of safflower, 50 parts of raw Burnet, 15 parts of Atractylodes macrocephala, 14 parts of arborvitae leaves, 12 parts of asparagus, 10 parts of blood jellyfish, 25 parts of Andrographis paniculata , 7 parts of agrimony, 8 parts of white back leaf, 8 parts of bletilla striata, 13 parts of golden fruit olive, 20 parts of aloe vera, 25 parts of borneol, 16 parts of black plum, 10 parts of Hedyotis diffusa, 11 parts of Tianqi, 22 parts of peach kernel, Guizhi 16 parts, Akebia 10 parts, honey 13 parts.

Further, the composition and parts by weight of the raw materials for making the traditional Chinese medicine composition are: 13 parts of Codonopsis pilosula, 4 parts of Acanthopanax, 8 parts of Usnea, 20 parts of Digupi, 18 parts of Gynostemma, 5 parts of Astragalus, 12 parts of Scutellaria baicalensis 5 parts of golden buckwheat, 3.5 parts of Daxue vine, 16 parts of Polygonum cuspidatum, 30 parts of safflower, 30 parts of raw Burnet, 18 parts of Atractylodes macrocephala, 9 parts of arborvitae leaves, 10 parts of asparagus, 6 parts of blood jellyfish, 22 parts of Andrographis paniculata , Agrimony 10 parts, white back leaves 4 parts, bletilla striata 5 parts, golden fruit olive 10 parts, aloe vera 13 parts, borneol 30 parts, black plum 20 parts, diffusa hedyotis 11 parts, Tianqi 12 parts, peach kernel 25 parts, Guizhi 22 parts, Akebia 12 parts, honey 18 parts.

Further, the composition and parts by weight of raw materials for making the traditional Chinese medicine composition are: 10 parts of Codonopsis pilosula, 3 parts of Acanthopanax, 6 parts of Usnea, 20 parts of Digupi, 16 parts of Jiaogulan, 7 parts of Astragalus, and 18 parts of Scutellaria baicalensis. 6 parts of golden buckwheat, 3 parts of Daxue vine, 18 parts of knotweed, 18 parts of safflower, 40 parts of raw Burnet, 20 parts of Atractylodes atractylodes, 12 parts of arborvitae leaves, 15 parts of asparagus, 12 parts of blood jellyfish, 28 parts of Andrographis paniculata , 8 parts of agrimony, 5 parts of white back leaf, 3 parts of bletilla striata, 11 parts of golden fruit olive, 15 parts of aloe vera, 17 parts of borneol, 14 parts of black plum, 7 parts of Hedyotis diffusa, 8 parts of Tianqi, 30 parts of peach kernel, 20 parts of Guizhi, 6 parts of Akebia, 15 parts of honey.

Further, the composition and parts by weight of raw materials for making the traditional Chinese medicine composition are: 11 parts of Codonopsis pilosula, 2 parts of Acanthopanax, 8 parts of Usnea, 30 parts of Digupi, 25 parts of Gynostemma, 6 parts of Astragalus, 13 parts of Scutellaria baicalensis 12 parts of golden buckwheat, 5 parts of Daxue vine, 13 parts of knotweed, 23 parts of safflower, 35 parts of raw Burnet, 16 parts of Atractylodes macrocephala, 14 parts of arborvitae leaves, 13 parts of asparagus, 8 parts of blood jellyfish, 30 parts of Andrographis paniculata , 9 parts of agrimony, 6 parts of white back leaf, 7 parts of bletilla striata, 12 parts of golden fruit olive, 18 parts of aloe vera, 28 parts of borneol, 27 parts of black plum, 5 parts of Hedyotis diffusa, 9 parts of Tianqi, 28 parts of peach kernel, 25 parts of Guizhi, 9 parts of Akebia, 10 parts of honey.

Further, the composition and parts by weight of raw materials for making the traditional Chinese medicine composition are: 12 parts of Codonopsis pilosula, 4 parts of Acanthopanax, 7 parts of Usnea, 28 parts of Digupi, 22 parts of Gynostemma, 4 parts of Astragalus, 15 parts of Scutellaria baicalensis 5 parts of golden buckwheat, 3 parts of Daxue vine, 14 parts of knotweed, 16 parts of safflower, 45 parts of raw Burnet, 19 parts of Atractylodes macrocephala, 11 parts of arborvitae leaves, 14 parts of asparagus, 9 parts of blood jellyfish, 23 parts of Andrographis paniculata , 7 parts of Agrimony, 7 parts of white back leaf, 8 parts of Bletilla striata, 9 parts of golden fruit olive, 14 parts of aloe vera, 19 parts of borneol, 22 parts of black plum, 9 parts of Hedyotis diffusa, 10 parts of Tianqi, 19 parts of peach kernel, 14 parts of Guizhi, 8 parts of Akebia, 20 parts of honey.

Further, the traditional Chinese medicine composition is made into an external ointment.

Further, the external ointment is prepared according to the following method:

(1) Take the raw medicinal materials of said parts by weight except borneol and honey and mix them in water for 2 hours, then place them in an extraction tank;

(2) Add step (1) to obtain water 8-10 times the total weight of the medicinal materials, decoct twice for 1.5-2 hours each time, filter, combine the filtrate, continue to boil over low heat, and concentrate into an extract shape, cooling;

(3) After the borneol is crushed and added into the extractum with honey, it is modulated into an external ointment, sterilized by ultraviolet irradiation, and packed into jars.

According to the theoretical research on burns in traditional Chinese medicine, traditional Chinese medicine believes that burns, as an external disease, occur due to the action of all strong heat, which invades the human body, and the flesh rots due to the heat, so that the skin and flesh rot. If the skin is injured by heat, if the damage is light (small area, shallow depth), it will only rot the skin and flesh, and will not affect the internal organs of the human body; if the damage is severe (large area, deep depth), the heat and poisonous gas will be blazing, not only the skin and flesh will rot, It can also cause significant changes in yin and yang, qi and blood, body fluids, and viscera functions throughout the body, damage yin fluid in the body, or attack viscera from the inside with heat toxins, resulting in disharmony between viscera and viscera, and imbalance of yin and yang. When heat and toxin invade, the skin and flesh suffer first. In shallower cases, the meridians are damaged, Qi and blood are blocked, and the veins are stagnant. The wound surface will be red, swollen, hot, painful, or blisters, or bleeding points, ecchymosis, or Eschar etc. If heat toxin accumulates, or exogenous pathogens are felt, it may become pus because of "the heat will cause the meat to rot". In severe cases (large area and deep depth), it can be caused by "the soup is extremely hot, forcing the poison to attack from the inside; there is also a cold and cold external injury, and the extremely poison enters the inside." It can also attack internally with heat and poison, causing systemic reactions, and even yin damage and yang, leading to yang detachment. Therefore, for mild cases of burns, only external therapy can be used; for patients with severe cases of large area burns, both internal and external treatment must be used. Wu Shangxian, a doctor in the Qing Dynasty, said, "The principle of external treatment is the principle of internal treatment, and the medicine of external treatment is the medicine of internal treatment. The difference is the method of ear." ". Therefore, clearing away heat and detoxification, relieving pain, reducing swelling and blood stasis, removing scabs and removing rot, detoxifying and lifting pus, and promoting muscle growth are important principles of external treatment for burns. The traditional Chinese medicine composition of the present invention is a medicine for external use, and the efficacy mechanism of the adopted Chinese medicinal materials is: Codonopsis pilosula tonifies the middle and Qi, invigorates the spleen and lungs, and Astragalus can nourish all deficiencies. Yang, consolidate the surface, drain pus, reduce swelling, the combination of Codonopsis pilosula and Astragalus membranaceus can best nourish the middle and Qi, and improve resistance; Polygonum cuspidatum has a strong inhibitory effect on Pseudomonas aeruginosa, Staphylococcus aureus, and various viruses, and it is a modern treatment for burns. The main drug; raw Burnet cools blood to stop bleeding, clears heat and detoxifies, reduces swelling and sores, and has inhibitory effect on various bacteria such as Pseudomonas aeruginosa; Acanthopanax enhances human immunity and resists free radical attacks, has antioxidant effect, can Enhance human immunity and prevent aging; Codonopsis pilosula, astragalus, Polygonum cuspidatum, Burnet burnet, Acanthopanax acanthopanax are monarch drugs; , Gynostemma pentaphyllum clears heat and detoxifies, Hedyotis diffusa clears heat and detoxifies, Ganhan clears dampness and heat, Scutellaria baicalensis has heat-clearing and damp-drying, cools blood and relieves miscarriage, and detoxifies, Golden Fruit Lam clears heat and detoxifies, sore throat, reduces swelling and pain, Golden buckwheat can clear heat, detoxify and activate blood Dispelling carbuncle, dispelling wind and dehumidifying sores, agrimony has the effect of promoting blood coagulation, shrinking peripheral blood vessels, shortening the clotting time, and increasing the number of platelets. It has the effect of cooling blood to stop bleeding, reducing carbuncle and swelling. Warming meridians, helping yang transforming qi, calming and lowering qi, Hedyotis diffusa, Andrographis paniculata, Arborvitae leaves, Usnea, Gynostemma, Scutellaria baicalensis, Agrimony, Golden fruit olive, Golden buckwheat, Guizhi are ministerial medicines; Lung relieves cough, astringent intestines relieves diarrhea, soothes ascariasis and relieves pain, promotes body fluid and quenches thirst, Digupi cools blood and removes steam, clears lungs and reduces fire, Baizhu strengthens spleen and replenishes qi, dries dampness and diuresis, asparagus nourishes yin and moistens dryness, clears lungs and promotes body fluid, Dried blood promotes blood circulation, dissipates blood stasis, hemostasis and promotes granulation. Sacred Teng has the functions of detoxifying and eliminating carbuncle, promoting blood circulation and dredging collaterals, expelling wind and killing insects. Blood stasis to relieve pain, ebony plum, Digupi, Atractylodes macrocephala, Radix Asparagus, Dried Blood, Daxueteng, Tianqi, peach kernel, and safflower are adjuvant medicines. White back leaf clears heat, dampness, relieves pain, detoxifies, stops bleeding, aloe vera sterilizes and sterilizes, borneol reduces swelling and relieves pain, clears away heat and disperses toxin, disperses fire and detoxifies, Mutong promotes water to reduce swelling, lowers dampness and heat, bletilla striata converges to stop bleeding, reduces swelling and promotes muscle growth, For hemoptysis and hematemesis, traumatic bleeding, sore swelling, chapped skin, white back leaf, akebia, aloe, borneol, and bletilla striata are used as medicines. Looking at the whole prescription, the compatibility is scientific and rigorous, and the medication is safe and effective.

Radix Codonopsis: flat in nature, sweet in the mouth, slightly sour; Return spleen, lung meridian. Invigorate the middle and replenish Qi, invigorate the spleen and lungs. For weakness of the spleen and lung, shortness of breath and palpitations, lack of food and loose stools, asthma and cough due to deficiency, internal heat and quenching thirst. This product is a commonly used qi-invigorating medicine in clinical practice. It has the function of invigorating the spleen and lungs, and its effect is similar to that of ginseng but weaker. Contained saponins, inulin, trace alkaloids, starch, etc. have different degrees of strengthening effects on multiple organs of the human body, and can improve the adaptability of the human body. It is anti-ulcer, can increase intestinal tension, regulate gastric motility, and reuse Codonopsis pilosula in gastrointestinal preparations for chronic diarrhea, ulcerative colitis, gastric antrum inflammation, and chronic atrophic gastritis.

Acanthopanax: Spicy, bitter, slightly sweet, warm in nature, enters the spleen, kidney, and heart meridian, has the effects of nourishing qi and invigorating the spleen, nourishing the kidney and calming the nerves, and expelling wind and dampness. , slow movement, physical weakness, bruises, fractures, edema, beriberi, yin damp itching and other symptoms. Acanthopanax gan A is carotene, which is also contained in ginseng. It can promote the excretion of cholesterol in the human body, and can prevent and treat hypercholesterolemia in the blood. Acanthopanax Glycyrrhizae B is Syringin, the main strong component of Acanthopanax senticosus, has gonadotropic, anti-radiation, anti-fatigue effects, and has similar physiological activities to ginseng saponin. Acanthopanax contains superoxide dismutase SOD (Superoxidedimutase) complex, SOD has good antioxidant function, can enhance human immunity and resist free radical attack, has antioxidant effect, can enhance human immunity, prevent aging and promote healthy.

Usnea: sweet, flat. Function cures mainly: heat-clearing and toxic substances removing, relieving cough and resolving phlegm. For pulmonary tuberculosis (usnic acid sodium salt), chronic bronchitis; external use for wound infection, postoperative incision infection, suppurative otitis media, boils, lymph node tuberculosis, mastitis, burns, cervical erosion, vaginal trichomonas.

Digupi: cold in nature, sweet in taste; enters the lung, liver, and kidney channels. "Bie Lu": "mainly rheumatism, lower chest and hypochondrium, heat headache, tonic for internal injuries, strong muscles, strong yin, sharp intestines, cold and heat." "Materia Medica": "Indications for fatigue, fever, Intercourse of cold and heat, blood syndrome, epistaxis, coughing blood, cough, wheezing, nausea, stroke, dizziness, convulsions, low back pain, numbness, beriberi, edema, restlessness, palpitations, forgetfulness, difficulty urinating, red and white turbidity. "Cooling the blood and removing steam, clearing the lungs and reducing fire. Indications for yin deficiency and labor-heat, bone steaming night sweats, malnutrition fever in children, thirst, lung cough and dyspnea, vomiting blood, epistaxis, hematuria. In modern times, it is used to treat hypertension, young flat warts, palmoplantar warts, generalized eczema, pulpitis pain, etc.

Gynostemma Gynostemma: sweet in the mouth, bitter, slightly cold in nature; Return lung meridian, spleen meridian, kidney meridian. Can replenish qi, soothe the nerves, lower blood pressure, clear heat and detoxify, relieve cough and eliminate phlegm. After a small number of patients took the medicine, symptoms such as nausea and vomiting, abdominal distension and diarrhea (or constipation), dizziness, vertigo, and tinnitus occurred. After taking Gynostemma pentaphyllum, the gastrointestinal motility is accelerated, the appetite is increased, and the time for resisting hunger and thirst is long, which not only cures constipation but also loose stools. The response to the excitation and inhibition of the cerebral cortex can maintain an appropriate balance, and it has a two-way regulating effect on the central nervous system. It has excellent analgesic, sleeping and anti-stress effects. On the basis of reducing myocardial wall tension and easing cerebrovascular and peripheral vascular resistance, it can enhance the vitality of the heart and brain, increase coronary artery flow, ease arteriosclerosis, and promote a more vigorous and smooth overall circulation. Experiments have shown that the group of Gynostemma pentaphyllum instead of greasy food, compared with the group of Gynostemma pentaphyllum without meat, has similar levels of cholesterol and neutral fat in the body through regular inspection. It can be seen that Gynostemma pentaphyllum has a benign transformation and regulation effect on body fat in the human body. Compared with rats that did not take Jiaogulan, their swimming time was about 31-57% longer, and their physical recovery was much faster. After taking Jiaogulan, people had more physical energy, less fatigue, and easy recovery even when tired, thus improving work efficiency. increase. A certain part of the human body is weak and will be allergic to certain substances, resulting in symptoms such as bronchial wheezing, skin pimples, and joint pain. Gynostemma pentaphyllum has a good effect on these diseases.

Fructus Radix: bitter, cold. Return lung, large intestine channel. "Properties of Medicine": "Detoxification. Throat numbness is urgent, mouth is rotten and should be taken. Acne and carbuncle are sent out on the back, red boils, snakes and scorpions, and scorpion wounds. Grinding. Treat eye pain, ear swelling, hot cough, miasma, and vomiting. All external diseases." "Little Knowledge of Orange Garden": "Dispel internal and external heat, all over the body vicious, eliminate miasma, double and single throat moth and toothache, cut into thin slices; grind and apply boils and swollen toxins." Function heat-clearing and toxic substances removing, diuresis Pharynx, reducing swelling and relieving pain. For sore throat, carbuncle furuncle, diarrhea, dysentery, abdominal pain. In addition to taking it orally in decoction, it can also be mashed with fresh grass for external application. For traumatic bleeding, dry grass can be ground into powder, spread and bandaged; for blood stasis, swelling and pain, appropriate amount of fresh grass can be smashed and applied externally.

Aloe vera: bitter and cold in taste, clearing liver heat, laxative, insecticidal; in addition, it is also used for headache, constipation, infantile epilepsy, malnutrition, boils, burns, ringworm, hemorrhoids, atrophic rhinitis, scrofula, Hepatitis, gallstones, eczema, etc. Aloe vera leaves contain more than 200 compounds, including 20 kinds of minerals, 18 kinds of amino acids, 12 kinds of vitamins and various other nutrients, including a variety of mucopolysaccharides, fatty acids, anthraquinones and flavonoids, sugars, active enzymes, etc. Anthraquinones, also known as Antraguinon Complex, have the effect of disinfection and sterilization, and mainly exist in the juice.

Borneolum: unblocks all orifices, disperses stagnant fire, removes nebula to improve eyesight, reduces swelling and relieves pain, clears away heat and disperses toxin, disperses fire and detoxifies. Treatment of mammary gland agglomeration, apoplexy, coma, coma due to febrile disease, convulsions, epilepsy, phlegm confusion, air-occlusion deafness, sore throat, mouth sores, otitis media, carbuncles, hemorrhoids, nebula, pinworms. ① "Bie Lu": "For women with dystocia, take a little borneol powder and mix it with freshly drawn water." ② "Tang Materia Medica": "Maintains evil spirits from trusted subordinates, rheumatism accumulation, deafness. Improve eyesight, remove red eyes and skin nebula "3. "Haiyao Materia Medica": "Main internal and external obstruction eyes, three worms, control five hemorrhoids, improve eyesight, calm the heart, secret essence." 4. Zhang Yuanyuan: "Treat large intestine prolapse." 5. Li Gao: "Treat bone pain "⑥Wang Haogu: "There is heat in the heart."⑦ "Compendium": "Treatment of sore throat, brain pain, snorting, toothache, typhoid tongue out, children's pox depression. Open all orifices, and disperse stagnant fire."⑧ "Compendium of Materia Medica": "Treat convulsions, epilepsy and phlegm fans." ⑨ "Meeting Medical Mirror": "Treat pain in limb joints."

Wumei: property of medicine is sour, puckery, flat. Return liver, spleen, lung, large intestine meridian; Efficacy: astringe the lung to relieve cough, astringe the intestine to stop diarrhea, relieve roundworm and relieve pain, promote body fluid to quench thirst.

Hedyotis diffusa is also called Hedyotis diffusa, Erye, Bamboo leaf vegetable, and Hedyotis diffusa. Taste slightly bitter, sweet, cold. Enter the stomach, large intestine, and small intestine meridian, bitter cold clears heat and detoxifies, sweet cold clears damp heat, and has strong detoxifying and eliminating carbuncle effects on carbuncles, sore throat, snake bites, etc. It is generally used to treat sores, sore throat, intestinal abscess and abdominal pain, snake bites, and it is also used for hot stranguria pain and dysuria. It is a good medicine for expelling toxins and dampness.

Tian Qi: It has the effects of dissipating blood stasis and stopping bleeding, reducing swelling and relieving pain. Indications for hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic bleeding, chest and abdomen tingling, tumbling pain. Taking Shengtianqi can promote blood circulation and remove blood stasis, reduce swelling and relieve pain, and can treat traumatic injuries;

Peach kernel: promoting blood circulation and dispelling blood stasis, moistening intestines and laxative, relieving cough and asthma. For amenorrhea, dysmenorrhea, lumps in the abdomen, tumbling injuries, intestinal dryness, constipation, blood stasis, anti-inflammatory effect, anti-allergic effect

Cinnamomum twig: Sweats and relieves muscles, warms meridians, helps yang transform qi, calms and lowers qi. For anemofrigid cold, cold pain in the abdomen, amenorrhea due to cold in blood, arthralgia, phlegm retention, edema, palpitation, running ton. It has anti-inflammatory, anti-allergic, antibacterial and antiviral effects, and is effective against Staphylococcus albus, Shigella dysenteriae, typhoid and paratyphoid A, pneumococcus, aerogenes, Proteus, anthrax, Salmonella enteritidis, Vibrio cholerae, etc. It also has an inhibitory effect.

Akebia: Used for hot stranguria, astringent pain, edema, etc., it can diuresis to reduce swelling, lower dampness and heat, and make dampness and heat go down and be excreted from urine. In vitro, it has inhibitory effect on Gram-positive bacteria and Gram-negative bacilli such as Shigella and Salmonella typhi. It also has different degrees of antibacterial effect on Trichophyton vioradis.

Radix Astragali can replenish all deficiencies, strengthen and support, and has the effects of nourishing qi, tonifying deficiency, promoting yang, strengthening the surface, draining pus, and reducing swelling. Modern medical research shows that it has obvious immune promotion and immune regulation functions. Studies have shown that astragalus can significantly improve the immune function of red blood cells in patients with large area burns, suggesting that in the treatment of large area burns, the application of astragalus can enhance the immune function of red blood cells in patients, thereby improving the overall immune function of patients and enhancing their body resistance. It has important clinical significance for preventing post-burn infection and improving the cure rate of severe burns. Radix Astragali is mainly used to invigorate deficiency, which can invigorate qi and solidify the exterior, diuretic and relieve toxins, drain pus, astringe sores and promote granulation. It is used for those with deficiency of Qi and blood, invagination of sores, pus that does not ulcerate or persists for a long time. Astragalus has a very good function of detoxifying and promoting granulation, that is, abscesses that have not healed for a long time suppurate and promote granulation. Modern medical research shows that astragalus contains a variety of antibacterial active ingredients, and can enhance the body's immune function, so it can also be used to prevent the occurrence of certain infectious diseases. "Materia Medica Fengyuan" contains: "Astragalus can nourish the deficiencies of the five internal organs, control the stringy pulse and spontaneous sweating, relieve Yin fire, and remove lung heat. If there is no sweat, it will stop, and if there is sweat, it will stop." It is a good medicine for improving resistance and preventing diseases.

Scutellaria baicalensis has heat-clearing and damp-drying, cooling blood and anti-abortion, detoxification effects. Indications for febrile disease, upper respiratory tract infection, lung-heat cough, damp-heat jaundice, pneumonia, dysentery, hemoptysis, red eyes, restless fetus, high blood pressure, carbuncle, swollen boils and other diseases. The clinical application of Scutellaria baicalensis is better than that of Coptis chinensis, and it does not produce drug resistance. With the help of the characteristics of strong broad-spectrum antibacterial effect, we use it in the fungal culture of miscellaneous bacterial infections, and the effect of using the extract of Scutellaria baicalensis is very good. "Ben Cao Jing Shu": Scutellaria baicalensis, its nature is clear and purifying, so it eliminates evils: it tastes bitter so it dries dampness; yin and cold so it overcomes heat, so it controls all heat. For those with all kinds of heat, pathogenic heat and pervasive heat, jaundice, intestinal withdrawal, and diarrhea are all diseases caused by damp heat. If you analyze the root, all diseases will heal by themselves. Bitter cold can remove dampness and heat, so the small intestine is sharp and the water is self-dispelling, and the source is clear and the flow is clean. For those with closed blood, the excess heat is in the blood system, that is, it heats up the blood chambers, causing amenorrhea. For malignant sores and ulcers, the blood heat will stay and become carbuncles, swollen and rotten; for fire sores, fire qi will damage the blood, and cooling the blood to remove heat will heal itself. Scutellaria baicalensis has anti-allergic and anti-inflammatory effects: baicalin and baicalein contained in scutellaria baicalensis can significantly inhibit the allergic contraction reaction of the isolated small intestine and isolated trachea of sensitized guinea pigs to antigens, and it is effective for passive systemic reactions in guinea pigs and mice. Allergic reactions and passive skin allergies in guinea pigs, baicalin and baicalein also have inhibitory effects. Scutellaria baicalensis has antipyretic effect, and most experiments have proved that the active ingredient baicalin in Scutellaria baicalensis has antipyretic effect. Scutellaria baicalensis has detoxification effect, and baicalin has obvious detoxification effect, which may be due to the fact that under the action of β-glucuronidase, baicalin decomposes glucuronic acid and combines with various poisons. 10 mg of baicalin can increase the LD50 of strychnine by 2.5 times, and increase the liver glycogen content of carbon tetrachloride poisoned mice.

Golden buckwheat: cool in nature, pungent and bitter in taste. Can heat-clearing and toxic substances removing, promoting blood circulation and eliminating carbuncle, expelling wind and dampness sores, snake and insect bites. Control lung carbuncle, lung-heat cough and asthma, sore throat, dysentery, rheumatic arthralgia, bruises, carbuncle and cancer.

Daxueteng: Bitter in taste, flat in nature, returns to the liver and large intestine meridian, "Hunan Medicine Chronicle": "Through the menstrual flow, nourish the blood, strengthen the muscles and bones, and repel insects. Treat bruises, rheumatism pain, blood dizziness, blood drenching, muscles and bones Pain, boils, blood filariasis." "Simple Herbal Medicine": "Treating muscle and bone pain, chasing wind, strengthening the waist and knees, and strengthening the yang." , Chronic appendicitis, rheumatism arthralgia, red dysentery, bloody stranguria, irregular menstruation, malnutrition, insect pain, injury from falls, etc. The effect on the isolated toad heart According to Yagi's isolated heart device, perfuse with 20ml Ren's solution, add 0.1g red rattan to the perfusate (0.5%), it is found that the isolated heart is slightly inhibited, showing contraction force weakened, the heart rate slowed down (P<0.05), and the cardiac output decreased (P<0.01). Effects on isolated rabbit aortic strips. The isolated rabbit aortic strips, as a result, the blood vessels began to show obvious constriction, which can be blocked by phentolamine, suggesting that its constriction may be related to a-receptor related. Then a lasting relaxation effect gradually appeared.

Polygonum cuspidatum slightly bitter, slightly cold. Return liver, gallbladder, lung meridian. Function clearing heat and detoxifying, invigorating the gallbladder and reducing jaundice, expelling wind and dampness, dispelling blood stasis and relieving pain, relieving cough and reducing phlegm. For arthralgia, damp-heat jaundice, amenorrhea, lumps in the abdomen, cough with excessive phlegm, water and fire burns, injury from falls, carbuncle and sore. "Yi Lin Zhuan Yao" contains it: strengthen the kidney, strengthen the yang and benefit the essence, strengthen the bones and muscles, and increase energy. Apply to the broken part of the fall, it can continue the tendons and bones.

Safflower is warm in nature and pungent in taste. Functions and indications apply to promoting blood circulation, dispelling blood stasis and relieving pain. For amenorrhea, dysmenorrhea, lochia, lumps in the abdomen, bruises. "Materia Medica Huiyan": Safflower, the medicine for breaking blood, promoting blood circulation, harmonizing blood, and regulating blood. The main fetal birth is caused by various diseases and blood, or blood troubles and blood dizziness, dizziness and silence; or lochia grabs the heart, umbilical abdominal colic; card, non-safflower cannot be cured. If postpartum haemorrhage, mouth shut up and finger pricking; or evil enters the blood chamber, delirium and madness; All such as amenorrhea with cold and heat, or expired abdominal pain with purple and black dripping, or injury with qi and blood stasis, or sores with itching and swollen ulcers are all symptoms of disharmony between qi and blood, and non-safflower cannot Tune in, safflower promote blood circulation and stimulate menstruation, reduce swelling and relieve pain, have the effects of inhibiting thrombosis, anti-inflammation, and pain relief, have the effect of constricting blood vessels by eliminating adrenaline and norepinephrine, and have the effect of "tongli meridian".

Raw Burnet bitter acid; cold; non-toxic, returns to liver; lung; kidney; large intestine meridian, cools blood to stop bleeding, clears heat and detoxifies, reduces swelling and sores, spits blood, hemoptysis, epistaxis, hematuria, hematochezia, hemorrhoids, dysentery, collapse Leakage, red and white discharge, sores, carbuncles, swollen pain, eczema, vulvar itching, water and fire burns, snake and insect bites. "Materia Medica Seeking Truth": Burnet, all books say that because of its bitter cold, it can enter the blood in the lower jiao to remove heat , Bi Rexi from the next solution. It is also said that the nature is heavy and astringent. Ordinary people suffer from vomiting, nosebleeds, dysentery, wind, blood and dysentery in the middle intestine. According to this, there is no difference. You know that if the heat is not eliminated, the blood will not stop. If the heat is cleared, the blood will be at ease, and its nature will be restrained. Vent, astringent also do not consider it or stagnation, strength antipyretic and hemostatic medicine also.

Atractylodes macrocephala bitter, sweet, warm. Return spleen, stomach warp. Function cures mainly: invigorating the spleen and replenishing qi, drying dampness and promoting diuresis, antiperspirant, antiabortive. For insufficiency of the spleen, lack of food, abdominal distension and diarrhea, dizziness and palpitation due to phlegm and retention, edema, spontaneous sweating, restless fetal movement. Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizoma Atractylodes Rhizome has the effect of invigorating the spleen and replenishing qi, drying dampness and promoting diuresis, antiperspirant and preventing miscarriage. For insufficiency of the spleen, lack of food, abdominal distension and diarrhea, dizziness and palpitation due to phlegm and retention, edema, spontaneous sweating, restless fetal movement. "Medical Genesis" records: "Dehumidification and dryness, harmonization and Qi, warming, removing dampness in the spleen and stomach, removing stomach heat, strengthening the spleen and stomach, eating and drinking, quenching thirst, and preventing miscarriage.

Arborvitae leaf: bitter, astringent, cold in nature, enters the heart, liver, and large intestine meridians, has the effect of cooling blood and stopping bleeding, dispels rheumatism, and dispels swelling and poison. , rheumatic arthralgia, bacillary dysentery, high blood pressure, cough, erysipelas, mumps, burns and other syndromes, arborvitae leaves can be used for wound redness, swelling and exudate, fever and irritability, dry mouth, fondness for drinking, constipation, short red urine, tongue quality Red crimson and dry, with yellow and rough fur, large and stringy pulse, has a good curative effect on heat-induced Yin syndrome, and has strong antibacterial effect, and can regulate visceral functions, replenish body fluids, reduce complications, and promote wound healing.

Asparagus: sweet, bitter, cold in nature, returns to the lung and kidney meridian, has the effect of nourishing yin and moistening dryness, clearing lung and promoting body fluid, mainly treating dry-heat cough, cough due to yin deficiency, hyperactivity of fire due to yin deficiency, nocturnal emission due to weak kidney essence, premature ejaculation And throat swelling and pain caused by asthenic fire and upper inflammation, febrile disease, fluid and wound thirst, internal heat, quenching thirst, intestinal dryness and constipation.

Draconis sanguis: Latin name Draconis Sanguis, sweet, salty, flat in nature, enters the heart, liver, and spleen meridians, has the effect of promoting blood circulation, dispelling blood stasis, stopping bleeding and promoting muscle growth, and is used for congestion, amenorrhea, dysmenorrhea, postpartum stasis, lumps in the abdomen , Chest and abdomen stabbing pain, bruises, congestion and swelling pain, traumatic bleeding, ulcers and other symptoms. medicine. Therefore, it is mainly used to break blood accumulation and golden sores, relieve pain and raw meat, and to control the evil qi of the five internal organs, that is, evil heat qi. Leukorrhagia is also caused by damp heat and blood damage. Sweet and salty can cool blood and remove heat, so it is known as the master. Su Gongzhu's confidant is suffering from pain, Li Xun uses it to treat injuries and injuries, all pains, blood qi stings, internal injuries and blood accumulation, sincerely for this ear.

Andrographis paniculata: bitter in taste, cold in nature, Guixin, lung, large intestine, bladder meridian, has heat-clearing and toxic substances removing, cooling blood, detumescence, the effect of drying dampness, cures mainly cold and fever, sore throat, aphtha of the mouth and tongue, sudden cough and labored cough, diarrhea Diarrhea and dysentery, hot stranguria pain, carbuncle sores, snake bites and other symptoms.

Agrimony, bitter, astringent, mild in nature, enters the lung, liver, and spleen meridian, Agrimin has the effect of promoting blood coagulation, shrinking peripheral blood vessels, shortening the coagulation time, and increasing the number of platelets. The effect of reducing swelling is used for traumatic bleeding, bleeding or bleeding during visceral surgery, and it also has antibacterial effects, especially strong inhibitory effects on Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa.

Radix Albae: cold, non-toxic. Heat-clearing, damp-dispelling, pain-relieving, detoxification, hemostasis. Cure stranguria, stomach pain, aphtha, hemorrhoids, ulcers, bruises, snake bites, traumatic bleeding; clove: pungent, warm; enters the stomach, spleen, kidney meridian, descending adverse, antifungal;

Bletilla striata: astringent hemostatic drug. Nature, flavor and meridian distribution: bitter, sweet, astringent, slightly cold. Return lung, liver, stomach warp. Functions and indications: astringent to stop bleeding, reduce swelling and promote muscle growth. For hemoptysis and hematemesis, traumatic hemorrhage, sore swelling, chapped skin; pulmonary tuberculosis hemoptysis, ulcer disease hemorrhage.

The pharmaceutical composition for the treatment of burns of the present invention is guided by modern medicine, pharmacology, and traditional Chinese medicine theories, and screens out drug compositions such as dredging meridians, harmonizing qi and blood, clearing away heat and detoxification, promoting blood circulation and reducing swelling, and fully embodies the detoxification and anti-inflammatory effects of externally used drugs. , Adsorption and convergence, decomposing and promoting granulation, can be applied to the treatment of any burns, has the characteristics of high cure rate, rapid pain relief, no scars, not limited by the treatment environment, convenient application, no toxic side effects, easy production, and low cost. . It has achieved good results in solving wound pain, infection, progressive tissue necrosis, scab, and scar after healing during burn treatment.

detailed description

In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions of the present invention will be clearly and completely described below in conjunction with the embodiments. Apparently, the described embodiments are part, but not all, of the present invention. Based on the described embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

Example 1:

A kind of traditional Chinese medicine composition that is used for treating burn of the present invention, take following traditional Chinese medicine crude drug: Codonopsis 9 parts, Acanthopanax 2 parts, Usnea 8 parts, Digupi 25 parts, Jiaogulan 20 parts, Radix Astragali 4 parts, Scutellaria baicalensis 16 parts, 10 parts of golden buckwheat, 4 parts of Rhododendron vine, 20 parts of Polygonum cuspidatum, 28 parts of safflower, 50 parts of raw Burnet, 15 parts of Atractylodes macrocephala, 14 parts of arborvitae leaves, 12 parts of asparagus, 10 parts of blood dragon, 25 parts of Andrographis paniculata 7 parts of agrimony, 8 parts of white back leaf, 8 parts of bletilla striata, 13 parts of golden fruit olive, 20 parts of aloe vera, 25 parts of borneol, 16 parts of black plum, 10 parts of Hedyotis diffusa, 11 parts of Tianqi, 22 parts of peach kernel , 16 parts of cassia twig, 10 parts of akebia, 13 parts of honey.

Example 2:

A kind of traditional Chinese medicine composition that is used for treating burn of the present invention, take the following traditional Chinese medicine raw materials: Codonopsis 13 parts, Acanthopanax 4 parts, Usnea 8 parts, Digupi 20 parts, Gynostemma 18 parts, Astragalus 5 parts, Scutellaria baicalensis 12 parts, 5 parts of golden buckwheat, 3.5 parts of Daxue vine, 16 parts of knotweed, 30 parts of safflower, 30 parts of raw Burnet, 18 parts of Atractylodes macrocephala, 9 parts of arborvitae leaves, 10 parts of asparagus, 6 parts of blood, and 22 parts of Andrographis paniculata 10 parts of agrimony, 4 parts of white back leaf, 5 parts of bletilla striata, 10 parts of golden fruit olive, 13 parts of aloe vera, 30 parts of borneol, 20 parts of black plum, 11 parts of Hedyotis diffusa, 12 parts of Tianqi, 25 parts of peach kernel , 22 parts of cassia twig, 12 parts of akebia, 18 parts of honey.

Example 3:

A kind of traditional Chinese medicine composition for treating burns of the present invention, take the following traditional Chinese medicine raw materials: Codonopsis 10 parts, Acanthopanax 3 parts, Usnea 6 parts, Digupi 20 parts, Gynostemma 16 parts, Astragalus 7 parts, Scutellaria baicalensis 18 parts, 6 parts of golden buckwheat, 3 parts of Daxue vine, 18 parts of knotweed, 18 parts of safflower, 40 parts of raw Burnet, 20 parts of Atractylodes macrocephala, 12 parts of arborvitae leaves, 15 parts of asparagus, 12 parts of blood, and 28 parts of Andrographis paniculata 8 parts of agrimony, 5 parts of white back leaf, 3 parts of bletilla striata, 11 parts of golden fruit olive, 15 parts of aloe vera, 17 parts of borneol, 14 parts of black plum, 7 parts of Hedyotis diffusa, 8 parts of Tianqi, 30 parts of peach kernel , 20 parts of cassia twig, 6 parts of akebia, 15 parts of honey.

Example 4:

A kind of traditional Chinese medicine composition for treating burns of the present invention, take the following traditional Chinese medicine raw materials: Codonopsis 11 parts, Acanthopanax 2 parts, Usnea 8 parts, Digupi 30 parts, Jiaogulan 25 parts, Astragalus 6 parts, Scutellaria baicalensis 13 parts, 12 parts of golden buckwheat, 5 parts of Rhododendron japonica, 13 parts of Polygonum cuspidatum, 23 parts of safflower, 35 parts of raw Burnet, 16 parts of Atractylodes macrocephala, 14 parts of arborvitae leaves, 13 parts of asparagus, 8 parts of blood jellyfish, 30 parts of Andrographis paniculata 9 parts of agrimony, 6 parts of white back leaf, 7 parts of bletilla striata, 12 parts of golden fruit olive, 18 parts of aloe vera, 28 parts of borneol, 27 parts of black plum, 5 parts of Hedyotis diffusa, 9 parts of Tianqi, 28 parts of peach kernel , 25 parts of cassia twig, 9 parts of akebia, 10 parts of honey.

Example 5:

A kind of traditional Chinese medicine composition that is used for treating burn of the present invention, take following traditional Chinese medicine crude drug: Codonopsis 12 parts, Radix Acanthopanax 4 parts, Usnea 7 parts, Digupi 28 parts, Gynostemma pentaphyllum 22 parts, Radix Astragali 4 parts, Scutellaria baicalensis 15 parts, 5 parts of golden buckwheat, 3 parts of Daxue vine, 14 parts of knotweed, 16 parts of safflower, 45 parts of raw Burnet, 19 parts of Atractylodes macrocephala, 11 parts of arborvitae leaves, 14 parts of asparagus, 9 parts of blood jellyfish, 23 parts of Andrographis paniculata 7 parts of agrimony, 7 parts of white back leaf, 8 parts of bletilla striata, 9 parts of golden fruit olive, 14 parts of aloe vera, 19 parts of borneol, 22 parts of black plum, 9 parts of Hedyotis diffusa, 10 parts of Tianqi, 19 parts of peach kernel , 14 parts of cassia twig, 8 parts of akebia, 20 parts of honey.

The Chinese medicine composition of above-mentioned embodiment 1-5 is made ointment, and concrete method is as follows:

The preparation method of described ointment is specifically the following steps:

(1) get each medical material of weight component shown in any one of above-mentioned embodiment 1-5, get the raw material medical material of described parts by weight except borneol and honey mix and soak in water for 2 hours, then place extraction tank middle;

(2) Add step (1) to obtain water 8-10 times the total weight of the medicinal materials, decoct twice for 1.5-2 hours each time, filter, combine the filtrate, continue to boil over low heat, and concentrate into an extract shape, cooling;

(3) After the borneol is crushed and added into the extractum with honey, it is modulated into an external ointment, sterilized by ultraviolet irradiation, and packed into jars.

Instructions:

After debridement, apply this ointment evenly on the wound surface with a thickness of 3-5mm, and wrap it with 3-4 layers of sterile gauze externally. The thickness of the dressing is determined according to the degree of exudation; apply the medicine once every 12-24 hours.

In addition, while using the drug treatment of the present invention, diet should be adjusted, and spicy food such as pepper, green onion and ginger, wine, etc., and high-calorie food such as mutton and dog meat should be avoided.

Toxicity test:

Take 30 healthy white guinea pigs, weighing 280-300g, both male and female, remove the back hair on both sides before the test, each side 3.5 × 4cm, and randomly divide them into a test group, a blank control group (matrix) and a positive control group. The positive control group used 2,4-dinitrochlorobenzene, the concentration of 1% was used for sensitization, and the concentration of 0.1% was used for excitation. Get 0.1 g of the ointment of Example 4 of the present invention and apply it to the depilated area on the back, once every other day, 3 times in total. 14 days after the last contact, apply 0.1g of this product on the same area of the back, observe immediately after removing the drug after 6 hours, and observe whether there is any allergic reaction at 24, 48, and 72 hours. The blank control group and the positive control group were stimulated, contacted and observed in the same way. Test results: the skin of the animals in the positive control group appeared localized erythema and slight edema 1 hour after the sensitization, and the symptoms of the allergic reaction aggravated in 24 hours, and there were indurations. The sensitization rate was 100%. The skin of the animals in the test group and the blank control group No allergic reaction symptoms occurred, and the sensitization rate was 0%.

Clinical Trials:

In order to verify the effect of the traditional Chinese medicine composition of the present invention, from January 2012 to September 2013, under the guidance of dermatologists at Qilu Hospital, 98 patients with burns were randomly selected in the outpatient clinic, all of whom had second-degree burns with an area of less than 9%. Burn patients were randomly divided into two groups: a treatment group and a control group, 49 cases in each group. The age, gender, and wound area of each group were statistically processed, P>0.05, and there was no significant difference. The external ointment made from the traditional Chinese medicine composition of Example 1 and the moist burn ointment for external application on the wound surface (produced by Shantou Meibao Pharmaceutical Co., Ltd., approved by National Drug Administration No. 2000004) were given to the above-mentioned two groups of patients respectively.

Treatment group: the external ointment that the traditional Chinese medicine composition of embodiment 1 is made, after debridement, evenly smear this ointment 3～5mm thickness on the wound surface, external use 3～4 layers of sterilized gauze bandage, decide dressing bandage according to exudation weight Thickness; apply once every 12-24 hours. Medication for 5-10 days.

Control group: Moist burn ointment (produced by Shantou Meibao Pharmaceutical Co., Ltd., Zhunzi No. 2000004), applied 2-4 times a day for 5-10 days.

Treatment criteria include four aspects: average pain relief time, average pain disappearance time, average healing time, and the number of cases of remaining scars. The curative effect was evaluated after 4 weeks of treatment. The treatment effect is shown in the table below:

group mean pain relief time mean time to pain disappearance average healing time The number of scars left control group 3 hours 102 hours 17 days 11 cases therapy group 3 minutes 7 hours 4 days 1 case

As can be seen from the above table, the treatment group is better than the control group in four aspects such as pain relief time, pain disappearance time, healing days and scar residual cases, which proves that the ointment of the present invention has obvious curative effect on burns.

Case 1:

Zhao, male, 5 years old, from the southern district of Qingdao, was burnt by alcohol flames on the face, right ear, neck, hands, and abdomen because the adults went out to play with fire by themselves. Degree 17%, III degree 17%, first transferred to our department after 5 days of hospital treatment, the wound surface has formed black scab, body temperature 38.7 ℃, heart rate 127 beats/min, the external use that adopts the traditional Chinese medicine composition of the present invention 2 to make Ointment, after debridement, apply this ointment evenly on the wound surface with a thickness of 3-5mm, and wrap it with 3-4 layers of sterile gauze externally. The thickness of the dressing is determined according to the degree of exudation; Afterwards, the black scabs all dissolved and fell off, new skin grew out of the superficial II degree wound, and the granulation tissue of the deep II degree wound was in good condition, and recovered after 30 days, maintaining the original appearance and physiological functions.

Case 2:

Qian, female, 47 years old, from Lixia District, Jinan City, fried twisted doughnuts at home in January 2013. The oil exploded due to water dripping into the boiling oil pan, resulting in multiple second-degree burns on the hands, forearms, and chest. It is more than 60 square centimeters, with blisters all over. Find our hospital after simple treatment at home, adopt the medicinal wine that the Chinese medicine composition of embodiment 3 is made, adopt the external ointment that the Chinese medicine composition of the embodiment of the present invention 2 is made, after debridement, evenly coat this ointment 3 on the wound surface ～5mm thickness, 3-4 layers of sterile gauze for external dressing, the thickness of the dressing is determined according to the degree of exudation, once every 3-4 hours, 5 times a day, and oral cephalosporin anti-inflammatory drugs for anti-inflammatory, every night at night Apply once every 4 hours. One day later, the wound pain was significantly relieved, accompanied by a cooling sensation, and after 4 days, the extravasated body fluid was significantly reduced. A week later, new pink tissue appeared on the skin at the edge of the affected area. After about 14 days, the new tissue gradually covered the affected area, and the patient recovered in about 20 days.

Case 3:

Sun, female, 4 years old, from Linzi, Zibo, was scalded by boiling water on her right lower limb, left thigh and perineum in August 2012. She went to a hospital for outpatient treatment for 4 days and did not improve. She was transferred to our hospital for examination: right thigh, calf, instep All of them had deep second-degree and third-degree burns, mild inflammatory reaction and infection. The left thigh and perineum were both deep and shallow second-degree burns. Treatment: disinfection, debridement, scab removal, removal of rotten skin and carrion, adopt the external ointment that the Chinese medicine composition of the embodiment of the present invention 5 is made, after debridement, evenly coat this ointment 3～5mm thickness on the wound surface, external use 3 ~ 4 layers of sterile gauze bandage, the thickness of the dressing is determined according to the severity of the exudation; every 12-24 hours, apply the dressing once, change the dressing on the 5th, the wound is clean, the adhesion is easy to bleed, the inflammation has been controlled, and the child’s mental appetite is normal. Change the dressing once a day. Dressing change on the 11th has basically healed. Healed after a month. After follow-up, the skin color was normal and no scars were produced.

Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: it can still be Modifications are made to the technical solutions described in the foregoing embodiments, or equivalent replacements are made to some of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims (9)

1. A Chinese medicine composition for treating burns, characterized in that: the crude drug of said Chinese medicine composition is composed of Codonopsis, Acanthopanax, Usnea, Digupi, Gynostemma pentaphyllum, Radix Astragali, Radix Scutellariae, Golden Buckwheat, Daxue Vine, knotweed, safflower, raw Burnet, Atractylodes atractylodes, orientalis leaves, asparagus, dried blood, andrographis, agrimony, white back leaves, bletilla striata, golden fruit olive, aloe vera, borneol, ebony, hedyotis diffusa, Tian Qi , peach kernel, cinnamon stick, akebia and honey. 2. The Chinese medicine composition for treating burns according to claim 1, characterized in that: the composition and parts by weight of raw materials for making said Chinese medicine composition are: Codonopsis 9-13 parts, Acanthopanax 2-4 6-8 parts of Usnea, 20-30 parts of Digupi, 16-25 parts of Gynostemma, 4-7 parts of Astragalus, 12-18 parts of Scutellaria baicalensis, 5-12 parts of golden buckwheat, 3-5 parts of Daxueteng, 13-20 parts of knotweed, 16-30 parts of safflower, 30-50 parts of raw Burnet, 15-20 parts of Atractylodes macrocephala, 9-14 parts of arborvitae leaves, 10-15 parts of asparagus, 6-10 parts of blood, and 22 parts of Andrographis paniculata -30 parts, 7-10 parts of agrimony, 4-8 parts of white back leaves, 5-8 parts of bletilla striata, 8-13 parts of golden fruit olive, 13-20 parts of aloe vera, 17-30 parts of borneol, 14-27 parts of black plum , 5-11 parts of Hedyotis diffusa, 8-12 parts of Tianqi, 19-30 parts of peach kernel, 14-25 parts of cassia twig, 6-12 parts of Akebia, 10-20 parts of honey. 3. The Chinese medicine composition for treating burns according to claim 2, characterized in that: the composition and parts by weight of raw materials for making said Chinese medicine composition are: 9 parts of Codonopsis Codonopsis, 2 parts of Acanthopanax, Usnea 8 parts, 25 parts of Digupi, 20 parts of Gynostemma, 4 parts of Astragalus, 16 parts of Scutellaria baicalensis, 10 parts of golden buckwheat, 4 parts of Daxueteng, 20 parts of Polygonum cuspidatum, 28 parts of safflower, 50 parts of raw Burnet, 15 parts of Atractylodes macrocephala, 14 parts of arborvitae leaves, 12 parts of asparagus, 10 parts of blood jellyfish, 25 parts of Andrographis paniculata, 7 parts of agrimony, 8 parts of white back leaves, 8 parts of bletilla striata, 13 parts of golden fruit olive, 20 parts of aloe vera, 25 parts of borneol, black plum 16 parts, 10 parts of Hedyotis diffusa, 11 parts of Tianqi, 22 parts of peach kernel, 16 parts of cassia twig, 10 parts of Akebia, 13 parts of honey. 4. The Chinese medicine composition for treating burns according to claim 2, characterized in that: the composition and parts by weight of raw materials for making said Chinese medicine composition are: 13 parts of Codonopsis Codonopsis, 4 parts of Acanthopanax, Usnea 8 parts, 20 parts of Digupi, 18 parts of Jiaogulan, 5 parts of Astragalus, 12 parts of Scutellaria baicalensis, 5 parts of golden buckwheat, 3.5 parts of Daxueteng, 16 parts of Polygonum cuspidatum, 30 parts of safflower, 30 parts of raw Burnet, 18 parts of Atractylodes macrocephala, 9 parts of arborvitae leaves, 10 parts of asparagus, 6 parts of blood jellyfish, 22 parts of Andrographis paniculata, 10 parts of agrimony, 4 parts of white back leaves, 5 parts of bletilla striata, 10 parts of golden fruit olive, 13 parts of aloe vera, 30 parts of borneol, black plum 20 parts, 11 parts of Hedyotis diffusa, 12 parts of Tianqi, 25 parts of peach kernel, 22 parts of cassia twig, 12 parts of Akebia, 18 parts of honey. 5. The traditional Chinese medicine composition for treating burns according to claim 2, characterized in that: the composition and parts by weight of raw materials for making said Chinese medicinal composition are: 10 parts of Codonopsis, 3 parts of Acanthopanax, Usnea 6 parts, 20 parts of Digupi, 16 parts of Gynostemma, 7 parts of Astragalus, 18 parts of Scutellaria baicalensis, 6 parts of golden buckwheat, 3 parts of Daxueteng, 18 parts of Polygonum cuspidatum, 18 parts of safflower, 40 parts of raw Burnet, 20 parts of Atractylodes macrocephala, 12 parts of arborvitae leaves, 15 parts of asparagus, 12 parts of dried blood, 28 parts of Andrographis paniculata, 8 parts of agrimony, 5 parts of white back leaves, 3 parts of bletilla striata, 11 parts of golden fruit olive, 15 parts of aloe vera, 17 parts of borneol, black plum 14 parts, 7 parts of Hedyotis diffusa, 8 parts of Tianqi, 30 parts of peach kernel, 20 parts of cassia twig, 6 parts of Akebia, 15 parts of honey. 6. The traditional Chinese medicine composition for treating burns according to claim 2, characterized in that: the composition and parts by weight of raw materials for making said Chinese medicinal composition are: Codonopsis 11 parts, Acanthopanax 2 parts, Usnea 8 parts, 30 parts of Digupi, 25 parts of Jiaogulan, 6 parts of Astragalus, 13 parts of Scutellaria baicalensis, 12 parts of golden buckwheat, 5 parts of Daxueteng, 13 parts of Polygonum cuspidatum, 23 parts of safflower, 35 parts of raw Burnet, 16 parts of Atractylodes macrocephala, 14 parts of arborvitae leaves, 13 parts of asparagus, 8 parts of blood jellyfish, 30 parts of Andrographis paniculata, 9 parts of agrimony, 6 parts of white back leaves, 7 parts of bletilla striata, 12 parts of golden fruit olive, 18 parts of aloe vera, 28 parts of borneol, black plum 27 parts, 5 parts of Hedyotis diffusa, 9 parts of Tianqi, 28 parts of peach kernel, 25 parts of Guizhi, 9 parts of Akebia, 10 parts of honey. 7. The Chinese medicine composition for treating burns according to claim 2, characterized in that: the composition and parts by weight of raw materials for making said Chinese medicine composition are: 12 parts of Codonopsis Codonopsis, 4 parts of Acanthopanax, Usnea 7 parts, 28 parts of Digupi, 22 parts of Gynostemma, 4 parts of Astragalus, 15 parts of Scutellaria, 5 parts of Golden Buckwheat, 3 parts of Daxueteng, 14 parts of Polygonum cuspidatum, 16 parts of safflower, 45 parts of raw Burnet, 19 parts of Atractylodes macrocephala, 11 parts of arborvitae leaves, 14 parts of asparagus, 9 parts of blood jellyfish, 23 parts of Andrographis paniculata, 7 parts of agrimony, 7 parts of white back leaves, 8 parts of bletilla striata, 9 parts of golden fruit olive, 14 parts of aloe vera, 19 parts of borneol, black plum 22 parts, 9 parts of Hedyotis diffusa, 10 parts of Tianqi, 19 parts of peach kernel, 14 parts of cassia twig, 8 parts of Akebia, 20 parts of honey. 8. The Chinese medicine composition for treating burns according to any one of claims 2-7, characterized in that: said Chinese medicine composition is made into an external ointment. 9. the Chinese medicine composition that is used for the treatment of burn according to claim 8, is characterized in that: described topical ointment is prepared according to the following method: (1) Take the raw medicinal materials of said parts by weight except borneol and honey and mix them in water for 2 hours, then place them in an extraction tank; (2) Add step (1) to obtain water 8-10 times the total weight of the medicinal materials, decoct twice for 1.5-2 hours each time, filter, combine the filtrate, continue to boil over low heat, and concentrate into an extract shape, cooling; (3) After the borneol is crushed and added into the extractum with honey, it is modulated into an external ointment, sterilized by ultraviolet irradiation, and packed into jars.