CN1985899B - Externally applied medicine for treating burns and scalds - Google Patents
Externally applied medicine for treating burns and scalds Download PDFInfo
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- CN1985899B CN1985899B CN200610022658A CN200610022658A CN1985899B CN 1985899 B CN1985899 B CN 1985899B CN 200610022658 A CN200610022658 A CN 200610022658A CN 200610022658 A CN200610022658 A CN 200610022658A CN 1985899 B CN1985899 B CN 1985899B
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Abstract
The externally applied medicine for treating burns and scalds consists of scorpion 5-20 weight portions, gallnut 10-30 weight portions, angelica 20-50 weight portions, gromwell 20-50 weight portions, and rhubarb 20-50 weight portions. It is used in treating burns and scalds mainly and has the features of fast acting, short treating period, less bacterial infection, no scar left after healing, low cost, etc. It may be also used in treating eczema, herpes, baby napkin dermatitis and other exudative dermatosis. The present invention also discloses the preparation process of the externally applied medicine.
Description
Technical field
The invention belongs to the pharmaceutical preparations technology field, particularly a kind of external used medicine for the treatment of burn and scald and preparation method thereof.
Background technology
Burn and scald is a kind of acute skin injury that takes place owing to hyperpyrexia material such as contact flame, boiled water, deep fat and electric current, some chemical substance etc., and is common clinically.
Burn and scald divides according to the injured degree of skin, once can be divided into, two the degree and three the degree burn and scald.The only outer damage of epidermis of burn and scald does not once injure skin corium, causes slight edema and pain, erubescence but do not have blister to produce, a few days rear peeling and healing.Two degree burn and scald epidermises and partly corium damage, be severe hyperemia, skin rubefaction, surface moisture, get blister, swelling and pain is relatively more severe, shallow two degree burn and scald can heal in two, three weeks, there is not tangible cicatrix, dark two degree burn and scald are not easily distinguishable with three degree burn and scald, and healing time is grown and stayed tangible cicatrix.Three degree burn and scald whole layer skin and subcutaneous tissue are damaged, and also are the holostrome burn and scald, also do not have blister because of the congested reaction of the downright bad event nothing of skin holostrome and form, and skin is white in color or is burned black, and is destroyed owing to teleneuron, generally do not have severe pain on the contrary; Owing to be difficult to own healing, needing to expand special treatments such as wound skin-grafting or benefit flap usually can fully recover, and its medical expense is very high.
Especially to two degree and the above burn and scald of two degree,,, provide favourable living environment, encouraged it and grow and breed, caused infection easily to antibacterial just as culture medium because wound surface oozes out the body fluid that contains the protein coagulation jelly in a large number; Even what have has formed thick crust piece on the wound surface surface, but in fact still have empyema to exist under the crust piece, make that the wound surface delay is difficult, the course of disease prolongs, and the patient is very painful.Usually need hospitalization, and generally need to cooperate to replenish body fluid and antibacterial therapy etc., the expense costliness also causes bigger financial burden to the patient.In addition, because does not have still clinically at present that treatment burn and scald effect is obvious, treatment time short and more after no clear scar, do not produce the ideal medicament of limbs adhesion etc., even after patient's recovery from illness, also tend to stay significantly cicatrix, height is low, sometimes black and white is mixed, perhaps stay tangible red scar etc., rather influence appearance; Severe patient is arranged even produce the limbs adhesion, can't restore, bring very big inconvenience for the patient body activity, have a strong impact in the future operate as normal and life.
Summary of the invention
The purpose of this invention is to provide a kind of external used medicine of new treatment burn and scald, that this external medication burn and scald has is rapid-action, short treating period, more the no clear scar in back, do not produce characteristics such as limbs adhesion.
Another object of the present invention provides a kind of preparation method of external used medicine of above-mentioned treatment burn and scald.
The technical solution adopted for the present invention to solve the technical problems is: a kind of external used medicine for the treatment of burn and scald, and it comprises following raw materials in weight portion medicine:
Scorpio 5-20 part, Galla Chinensis 10-30 part, Radix Angelicae Sinensis 20-50 part,
Radix Arnebiae (Radix Lithospermi) 20-50 part, Radix Et Rhizoma Rhei 20-50 part.
The weight portion proportion optimization of above-mentioned each crude drug is:
Scorpio 5-15 part, Galla Chinensis 10-20 part, Radix Angelicae Sinensis 20-40 part,
Radix Arnebiae (Radix Lithospermi) 20-40 part, Radix Et Rhizoma Rhei 20-40 part.
The weight portion proportioning of above-mentioned each crude drug is more preferably:
10 parts of Scorpios, 15 parts of Galla Chinensiss, 30 parts of Radix Angelicae Sinensis,
30 parts of Radix Arnebiae (Radix Lithospermi)s, 30 parts of Radix Et Rhizoma Rhei.
The external used medicine of above-mentioned treatment burn and scald is preferably oil preparation (can be liniment, stick agent or spray etc.).
The external used medicine that the present invention treats burn and scald can prepare by following method: each crude drug of getting described weight portion proportioning, with water or alcohol or vegetable oil is solvent, adopt infusion process or percolation to extract, make external used medicine according to the conventional preparation method of various drug forms again, get final product.
The preparation method of above-mentioned external used medicine is preferably: getting each crude drug of described weight portion proportioning, is solvent with the vegetable oil, adopts infusion process or percolation to extract, and makes the oil preparation that concentration is 10-20g crude drug/100ml, gets final product.
Solvent vegetable oil in the above-mentioned oil preparation preparation method is preferably Oleum sesami.
The selected crude drug of external used medicine that the present invention treats burn and scald is the Chinese medicine that meets the relevant drug standard of country, wherein:
Scorpio is the dry body of Buthidae animal Scorpio Buthus martensii Karsch;
Galla Chinensis is the insect gall on Anacardiaceae plant Fructus rhois chinensis Rhus chinensis Mill., blue or green bran poplar Rhuspotaninii Maxim. or Radix Rhois Sinicae Rhus punjabensis Stew.var.sinica (Diels) the Rehd.et Wils leaf, is mainly formed by melaphis chinensis Baker Melaphis chinensis (Bell) Baker parasitism;
When the dry root that is classified as umbelliferae angelica Angelica sinensis (Oliv.) Diels;
Radix Arnebiae (Radix Lithospermi) is the dry root of comfrey lithospermum euchromum Royle Arnebia euchroma (Royle) Johnst, Radix Arnebiae (Radix Lithospermi) Lithospermum erythrorhizon Sieb.et Zucc. or arnebia guttata Bunge Arnebia guttataBunge;
Radix Et Rhizoma Rhei is the dry root and rhizome of polygonum rheum palmatum Rheum palmatum L., Rheum tanguticum Rheumtenguticum Maxim.ex Balf. or Rheum officinale Rheum officinale Baill..
Compared with prior art, the invention has the beneficial effects as follows: the external used medicine that the present invention treats burn and scald screens above-mentioned five tastes Chinese medicine composition meticulously, has following characteristics:
(1), to be used for the treatment of burn and scald pain killing fast, effective, coats about medicine 15min of the present invention, pain can obviously alleviate, disappear gradually, alleviates the patient suffering;
(2), can check body fluid and exosmose, purify wound surface, do not produce the environment that helps bacteria breed and breeding, even be exposed in the air, also can reduce the possibility of traumatic infection; And generally do not need additionally to replenish body fluid and carry out antibacterial therapy, can simplify therapeutic process; Also can avoid the formation of wound surface crust piece and promote established crust piece to come off, accelerate healing;
(3), can obviously improve the wound surface local circulation, it is ruddy that pale wound surface is transferred, and accelerates healing, makes illing skin return to normal or near normal condition, residual, the no limbs adhesion of no cicatrix etc.;
(4), medicine material cost of the present invention is lower, and treatment time is shorter, also can obviously alleviate patient's financial burden.
In addition, external used medicine of the present invention also has an excellent curative to eczema, herpes, baby diaper dermatitis, ulcer and other exudative skin are ill etc.
The specific embodiment
The present invention is described in further detail below in conjunction with the specific embodiment.
But this should be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following embodiment.Do not breaking away under the above-mentioned technological thought situation of the present invention, various replacements or change according to ordinary skill knowledge and customary means are made include within the scope of the invention.
Embodiment 1
Present embodiment is the oil preparation (liniment) of treatment burn and scald, is made by following weight parts proportion raw material medicine:
10 parts of Scorpios, 15 parts of Galla Chinensiss, 30 parts of Radix Angelicae Sinensis,
30 parts of Radix Arnebiae (Radix Lithospermi)s, 30 parts of Radix Et Rhizoma Rhei.
The liniment of present embodiment treatment burn and scald can prepare by the following method: getting each crude drug of described weight portion proportioning, is solvent with the Oleum sesami, adopts infusion process to soak more than 1 month, and making concentration is the oiliness liniment of 15g crude drug/100ml, gets final product.
Embodiment 2
Present embodiment is the oil preparation (spray) of treatment burn and scald, is made by following weight parts proportion raw material medicine:
15 parts of Scorpios, 10 parts of Galla Chinensiss, 50 parts of Radix Angelicae Sinensis,
40 parts of Radix Arnebiae (Radix Lithospermi)s, 20 parts of Radix Et Rhizoma Rhei.
The spray of present embodiment treatment burn and scald can prepare by the following method: getting each crude drug of described weight portion proportioning, is solvent with the Oleum sesami, adopts percolation to extract, and making concentration is the oiliness spray of 10g crude drug/100ml, gets final product.
Embodiment 3
Present embodiment is the oil preparation (sticking agent) of treatment burn and scald, is made by following weight parts proportion raw material medicine:
20 parts of Scorpios, 20 parts of Galla Chinensiss, 40 parts of Radix Angelicae Sinensis,
20 parts of Radix Arnebiae (Radix Lithospermi)s, 50 parts of Radix Et Rhizoma Rhei.
The spray of present embodiment treatment burn and scald can prepare by the following method: each crude drug of getting described weight portion proportioning, with the Oleum sesami is solvent, adopts percolation to extract, and getting concentration is the oily solution of 12g crude drug/100ml, make by the routine fashion that sticks agent again and stick agent, get final product.
Embodiment 4
Present embodiment is the oil preparation (liniment) of treatment burn and scald, is made by following weight parts proportion raw material medicine:
5 parts of Scorpios, 30 parts of Galla Chinensiss, 20 parts of Radix Angelicae Sinensis,
50 parts of Radix Arnebiae (Radix Lithospermi)s, 40 parts of Radix Et Rhizoma Rhei.
The liniment of present embodiment treatment burn and scald can prepare by the following method: getting each crude drug of described weight portion proportioning, is solvent with Oleum Camelliae, adopts infusion process to soak more than 2 months, and making concentration is the oiliness liniment of 20g crude drug/100ml, gets final product.
Embodiment 5
Present embodiment is the ointment of treatment burn and scald, is made by following weight parts proportion raw material medicine:
10 parts of Scorpios, 25 parts of Galla Chinensiss, 30 parts of Radix Angelicae Sinensis,
35 parts of Radix Arnebiae (Radix Lithospermi)s, 30 parts of Radix Et Rhizoma Rhei.
The ointment of present embodiment treatment burn and scald can prepare by the following method: each crude drug of getting described weight portion proportioning, alcoholic solution with 70% is a solvent, the employing percolation extracts, reclaim ethanol, be condensed into thick paste, add percentage by weight respectively and be 15% vaseline as ointment base, make ointment, get final product according to the conventional preparation method of ointment.
The model case brief introduction:
Patients such as a burn and scald patient and tens of eczema, herpes carried out clinical treatment observation surplus the inventor had been applied to 100 with product of the present invention, had all obtained excellent curative, and back preventing from scar more.
Using method is: after wound surface is carried out cleaning-sterilizing; get external used medicine of the present invention and directly wound surface is sticked, embrocates or sprays, have the blister place to squeeze the one's water breaks bubble earlier, drain the water away; re-use medicine of the present invention, generally do not need additionally to replenish colloidal liquid and carry out antibacterial therapy.
Below use the simple scenario of medicine of the present invention for some cases:
Case one: Li Deyuan, the former terylene retired worker of factory in Guanghan City, Sichuan Province, man, 50 years old.Because of the gas furnace misoperation causes 1-2 ° of burn, area is about about 20%, uses medicine of the present invention simultaneously at the transfusion anti-infective in preceding 3 days, is clearly better after 3 days; After no longer transfusion, only use medicine oil preparation of the present invention to continue treatment, crust begins to come off voluntarily after 5 days, does not have the phenomenon of infection, accuses more after 7 days.
Case two: Lv Ronghua, Wu Jin town, Xinjin County, Sichuan Province resident, man, 38 years old.Located by the thoughtful both feet back of the body in 1/3 place one on petrol burn both hands, the left hand elbow arm outside, left knee actuator current amplifier, the two lower limb ankle joint etc., all burn positions all present blister, burn position skin is burned black, obvious purulent secretion is arranged, about 2 ° of burn degree, because of financial difficulties, only adopted penicillin, streptomycin and certain lotion simple therapy such as (not quite clear) at preceding 4 days that have just burnt, the condition of the injury does not alleviate.The back uses medicine oil preparation of the present invention (oral doxycycline simultaneously) to begin to take a turn for the better after 2 days, and transudate obviously reduces, and crust begins to come off voluntarily after 5 days, and wound surface is ruddy, and crust comes off substantially and totally accuses more after 12 days; 3 months after burning traumatic part bit recoveries are to normal, and no cicatrix is residual.
Case three: Hao faithful and upright person, Xinjin County, Sichuan Province self-employed businessman, man, 37 years old.Scalded by boiled water, the inboard about 10cm of left upper arm * 10cm epidermis is scalded at once, all bubbles in positions such as the right lower extremity shin calf about 40cm * 20cm of portion, right crus of diaphragm neck and the about 20cm * 15cm of instep.Once local hospital hospitalization 5 days, blank wall.Before using medicine of the present invention, the inboard about 20cm * 40cm of upper arm, the about 10cm of right lower extremity shin calf portion * 10cm area be infection suppurates, surplus see that position, institute traumatic part has that 1cm, 2cm, 3cm differ in size be dispersed in the pus point, the beancurd sheet of all injuries does not all come off; Whole left upper extremity is the canescence edema, little existing adhesion shape between finger; Constantly following of the body fluid that wound surface oozes out.After stabbing out blister, eliminating hydrops, wound surface sterilization, soak gauze piece with medicine oil preparation of the present invention and stick wound surface, keep gauze to soak into humidity.Wound surface no longer oozes out body fluid after 1 day, and edema obviously alleviates; Wound surface is transferred ruddyly after 2 days, obviously disappears in former infection position; Beancurd sheet begins to come off voluntarily after 3 days; The basic announcement more after 7 days; Follow up a case by regular visits to after 3 months, all are scalded the position and recover fully normally not stay any vestige.
Case four: Wang Mingyuan, Wu Jin town, Xinjin County, Sichuan Province resident, man, 70 years old.Scalded by boiled water, left lower extremity from thigh 1/2 place until instep, the about 20cm * 60cm of its area, all over getting blister, the condition of the injury does not wait for 1 °, 2 °, boiling hot position is burns sample pain.After stabbing out blister, eliminating hydrops, wound surface sterilization, soak gauze piece with medicine oil preparation of the present invention and stick wound surface, keep gauze moistening.Wound surface is all right after 2 days, no longer oozes out body fluid, does not also have purulent secretion and occurs; Wound surface cleaning after 5 days does not also have secretions, does not have the phenomenon of infection; Wound surface obviously transfers to ruddyly after 6 days, and beancurd sheet begins to come off voluntarily; Trend recovery from illness after 8 days; Follow up a case by regular visits to after 1 month, all are scalded vestige and gradually dissipate, and return to fully after 2 months normally, do not stay any vestige.
Case five: Peng Rui, Xinjin County, the Sichuan Province new meaning villeggiatura people, man, 4 years old.Scalded by boiled water, injure right side facial area, cervical region, the big portion of right front breast, right dorsal part to waist, right upper extremity etc. and locate, belong to severe scald, 1 °, 2 °, dark 2 ° are not waited, in the elsewhere treatment commentaries on classics of not getting better in 7 days.Before using medicine of the present invention, neck surface about 40%, right upper extremity is about 90%, and the right side trunk is about 80%, and wound surface body fluid oozes out seriously, right upper extremity is the mulberry edema, cervical region, oxter, finger etc. have been located obvious purulent secretion, and obvious infection phenomenon is arranged, and present slight adhesion between finger, with 38.4 ℃ of low grade fever, infant mental status extreme difference.After stabbing out blister, eliminating hydrops, wound surface sterilization, soak into wound surface with medicine oil preparation of the present invention, simultaneously oral Chinese medicine decoction with antipyretic and antidote functions, temperature recovery is normal after 3 days, and wound surface crust BOB(beginning of block) comes off voluntarily, and no body fluid oozes out, no purulent secretion, the infant mental status is clearly better; Most of wound surface trend is accused more after 7 days; Follow up a case by regular visits to after 2 months, except that minority was dispersed in white point, all the other were scalded the position and recover to be normal skin, do not leave a trace.
By the treatment to above-mentioned burn and scald patient, average course of disease is about 10 days, and its therapeutic process can roughly be divided into three phases, that is: 1. check body fluid and exosmose the stage, also be the stage of most critical in the therapeutic process, as in 24-48 hour, can reach this effect; 2. beancurd sheet or eschar skin come off the stage, allow its free voluntarily wound surface, and metabolism comes off, and can not tear by force; 3. consolidate the effect stage, use medicine of the present invention to keep wound surface to soak into, coming off to beancurd sheet or eschar skin comes off fully, and illing skin returns to normal or near normal condition.As seen, the curative effect highly significant of medicine of the present invention, effective, rapid-action, average course of disease only need got final product decrustation in about ten days, the continuous use 1-2 month or longer time, even can make patient skin return to burn and scald normal condition before, no cicatrix is residual, does not produce limbs adhesion etc.
Claims (6)
1. external used medicine for the treatment of burn and scald, it is by following raw materials in weight portion medicine, is solvent with water or alcohol or vegetable oil, adopts infusion process or percolation to extract, and makes according to the conventional preparation method of various drug forms again:
5～20 parts of Scorpios, Galla Chinensis 10-30 part, Radix Angelicae Sinensis 20-50 part,
Radix Arnebiae (Radix Lithospermi) 20-50 part, Radix Et Rhizoma Rhei 20-50 part.
2. the external used medicine of treatment burn and scald according to claim 1 is characterized in that: the weight portion proportioning of described each crude drug is:
Scorpio 5-15 part, Galla Chinensis 10-20 part, Radix Angelicae Sinensis 20-40 part,
Radix Arnebiae (Radix Lithospermi) 20-40 part, Radix Et Rhizoma Rhei 20-40 part.
3. the external used medicine of treatment burn and scald according to claim 2 is characterized in that: the weight portion proportioning of described each crude drug is:
10 parts of Scorpios, 15 parts of Galla Chinensiss, 30 parts of Radix Angelicae Sinensis,
30 parts of Radix Arnebiae (Radix Lithospermi)s, 30 parts of Radix Et Rhizoma Rhei.
4. according to the external used medicine of each described treatment burn and scald among the claim 1-3, it is characterized in that: described external used medicine is an oil preparation.
5. the external used medicine of treatment burn and scald according to claim 4 is characterized in that: described external used medicine is made by following method:
Getting each crude drug of described weight portion proportioning, is solvent with the vegetable oil, adopts infusion process or percolation to extract, and makes the external used medicine that concentration is 10-20g crude drug/100ml, gets final product.
6. the external used medicine of treatment burn and scald according to claim 5 is characterized in that: described vegetable oil is an Oleum sesami.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610022658A CN1985899B (en) | 2006-12-26 | 2006-12-26 | Externally applied medicine for treating burns and scalds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200610022658A CN1985899B (en) | 2006-12-26 | 2006-12-26 | Externally applied medicine for treating burns and scalds |
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| Publication Number | Publication Date |
|---|---|
| CN1985899A CN1985899A (en) | 2007-06-27 |
| CN1985899B true CN1985899B (en) | 2010-05-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN200610022658A Expired - Fee Related CN1985899B (en) | 2006-12-26 | 2006-12-26 | Externally applied medicine for treating burns and scalds |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105816700A (en) * | 2016-03-25 | 2016-08-03 | 广西大学 | External application ointment for treating scalds and burns |
| CN108671176A (en) * | 2018-07-13 | 2018-10-19 | 黄颖 | A kind of preparation method of the plant extract Chinese medicine composition of external curing diaper rash |
| CN109125712A (en) * | 2018-09-26 | 2019-01-04 | 南阳市中心医院 | A kind of burned infants scald anesthesia dressing patch |
| CN114272384A (en) * | 2021-12-24 | 2022-04-05 | 厦门一泰消防科技开发有限公司 | Application of fire-fighting water additive in burn and scald emergency treatment |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1104509A (en) * | 1993-12-31 | 1995-07-05 | 刘永录 | Medicine for burn and its preparation |
| CN1836701A (en) * | 2005-03-22 | 2006-09-27 | 刘智伟 | Scald-treating medicine |
-
2006
- 2006-12-26 CN CN200610022658A patent/CN1985899B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1104509A (en) * | 1993-12-31 | 1995-07-05 | 刘永录 | Medicine for burn and its preparation |
| CN1836701A (en) * | 2005-03-22 | 2006-09-27 | 刘智伟 | Scald-treating medicine |
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| Publication number | Publication date |
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| CN1985899A (en) | 2007-06-27 |
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