CN108853242A - A kind of high-efficiency burn treating medicine and its preparation method and application - Google Patents
A kind of high-efficiency burn treating medicine and its preparation method and application Download PDFInfo
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Classifications
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- A61K36/18—Magnoliophyta (angiosperms)
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- A—HUMAN NECESSITIES
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- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
- A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract
The invention proposes a kind of high-efficiency burn treating medicines, are prepared by weight by following raw material：5-25 parts of corydalis tuber, 5-20 parts of the root of Dahurain angelica, 10-25 parts of Cortex Phellodendri, 5-15 parts of garden burnet, 10-25 parts of polygonum cuspidate, 5-20 parts of calamine, 800-1200 parts of vaseline, 40-80 parts of borneol.Burn-scald medicine prepared by the present invention has analgesic is fast, it is fast to heal, the general preventing from scar of 1 or 2 degree of burn, occlusive dressing nursing is convenient, painless dressing debridement is thorough and other effects, and raw material sources are wide, preparation method is simple, preparation cost is low, curative effect is fast, it takes effect, convenient transportation and storage, therefore be with a wide range of applications.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, and in particular to a kind of burn-scald medicine.
Background technique
Water, burning hot wound are one of common clinicals, it keeps Principle of Pain hard to bear, suffers untold misery.Currently, traditional Chinese and western medicine has perhaps
Drug and method have certain effect to treatment scald, but also have insufficient place.The side of western medical treatment burn and scald
Method is usually to use debridement, disinfection, exposure method and operation, and the course for the treatment of is long, and healing is slow, costly, and more after there are scars.In
Doctor is treated using Chinese medicine, there is the effect of certain detumescence stops disease in the application, but all has the long disadvantage of wound healing time.It burns
It is in great pain for scalding the first symptom.This is because microcirculation is destroyed, vasopermeability increases, microcirculation thrombosis,
Occur in be solidification, in be retarded by silt, be outside hyperemia phenomenon caused by.The maximum danger of burn and scald is infection.Due to the micro- blood of the surface of a wound
Wound site is not achieved clinically by blood circulation conveying antibiotic in pipe embolism, the immune substances such as antibody, haemocyte cannot and
When supply the surface of a wound, thus anti-infection effect is undesirable.Therefore burnt degree therapeutic effect will make the wound of patient heal completely, sick and wounded
Member restores the function of body kinematics to the maximum extent, also to restore the function of each system, each internal organs, while also to restore outer as far as possible
Shape.This is the boundary that modern burn rehabilitation technology is pursued.
In addition, the drug and method of existing treatment burn and scald, usually will form many incrustations, influence beauty, this is also most
The new issue that should be researched and solved.
Summary of the invention
In order to solve the above technical problems, the present invention provides a kind of high-efficiency burn treating medicine and its preparation method and application,
It is intended that providing a kind of high-efficiency burn treating medicine, by the way that Chinese medicinal powder is prepared into burn-scald medicine, has and relieve pain fast, healing
Fastly, (1,2 degree burn general preventing from scar), occlusive dressing nursing be convenient, painless dressing debridement thoroughly and other effects.
The present invention provides a kind of high-efficiency burn treating medicine, is prepared by weight by following raw material：5-25 parts of corydalis tuber, the root of Dahurain angelica
5-20 parts, 10-25 parts of Cortex Phellodendri, 5-15 parts of garden burnet, 10-25 parts of polygonum cuspidate, 5-20 parts of calamine, 800-1200 parts of vaseline, borneol
40-80 parts.
As further improvement of the invention, it is prepared by weight by following raw material：10-20 parts of corydalis tuber, root of Dahurain angelica 10-
17 parts, 12-20 parts of Cortex Phellodendri, 8-15 parts of garden burnet, 13-20 parts of polygonum cuspidate, 7-18 parts of calamine, 900-1100 parts of vaseline, borneol 45-
70 parts.
As further improvement of the invention, it is prepared by weight by following raw material：15 parts of corydalis tuber, 15 parts of the root of Dahurain angelica,
15 parts of Cortex Phellodendri, 15 parts of garden burnet, 15 parts of polygonum cuspidate, 15 parts of calamine, 1000 parts of vaseline, 60 parts of borneol.
The present invention further protects a kind of preparation method of high-efficiency burn treating medicine, prepares in accordance with the following methods：By corydalis tuber, white
The root of Dahurian angelica, Cortex Phellodendri, garden burnet, polygonum cuspidate, calamine beat powder, obtain mixed powder, and borneol is added, and uniformly, vaseline, leaching is added in ultrasonic agitation
24-72h is steeped, continues to stir evenly, is placed at room temperature for 3-5 days to get high-efficiency burn treating medicine.
As further improvement of the invention, the partial size number of mixed powder is between 100-200 mesh.
As further improvement of the invention, ultrasound condition is 500-700W ultrasound 30-60min.
As further improvement of the invention, mixing speed 300-500r/min.
The present invention further protects a kind of high-efficiency burn treating medicine yarn, which is characterized in that the high-efficiency burn treating medicine yarn is by upper
High-efficiency burn treating medicine is stated to be prepared coated in gauze layer inner surface.
As further improvement of the invention, gauze 15X25cm2Single layer sterile gauze.
As further improvement of the invention, gauze layer is suppressed by 100 gauzes.
Medicinal material used by efficient ointment for treating scald of the invention is chosen according to herbal pharmacology and Chinese traditional treatment theory, middle part
The pharmacological property of drug dispensing material is as follows：
Corydalis tuber, warm-natured, acrid flavour is bitter, enters the heart, spleen, liver, lung, is the quality goods of activating microcirculation and removing stasis medicinal, promoting qi circulation and relieving pain, gas in energy promoting circulation of blood
It is stagnant, stasis in gas, therefore specially control all pains above and below all over the body；
The root of Dahurain angelica, nature and flavor:It is warm-natured, acrid flavour, gas fragrance, slight bitter, wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving.For having a headache, tooth
Bitterly, nasosinusitis, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, pruitus；
Cortex Phellodendri, bitter are cold in nature.Clearing heat and detoxicating, purging intense heat eliminating dampness cures mainly acute bacillary dysentery, chordapsus, acute jaundice
The inflammation such as type hepatitis, urinary system infection contamination.Burning hot wound, tympanitis, acute conjunctivitis etc. are controlled in external application；
Garden burnet, cold in nature, bitter acid are nontoxic；Return liver, lung, kidney and large intestine channel.There is cooling blood and hemostasis, it is clearing heat and detoxicating, train clear support
Yin, healing up sore and subduing swelling and other effects；
Polygonum cuspidate, mildly bitter flavor, cold nature have removing dampness through diuresis and removing jaundice, clearing heat and detoxicating, removing blood stasis and acesodyne, relieving cough and reducing sputum effect.For
Jaundice with damp-heat pathogen, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, carbuncle sore tumefacting virus, scald, menostasis, abdominal mass, instep beat damage, cough with lung heat；
Calamine is natural magnesium zinc not soluble in water, dermatology is widely used in, as the anti-corrosion of moderate, convergence, protective agent
Treat scytitis or surface injury；
Borneol, acrid flavour are bitter, slightly cold, gas faint scent, hide refrigerant, and that chews then slowly dissolves, and cures mainly and leads to all keys, dissipates stagnated fire, goes screen
Improving eyesight, swelling and pain relieving.Control apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm confusing heart, deafness with qi stagnation, sore throat, aphtha, tympanitis, carbuncle swells, hemorrhoid
Sore, mesh also screen film, enterobiasis.
The present invention has the advantages that：
1. analgesic is fast, (this medicine can obviously reduce sensation of pain in about 15 minutes after use, persistently reach only within 1-24 hours
Pain peak value)；
2. fast (for shallow 2 degree burns, heal for face 3 days or so, trunk and healing in four limbs 5-7 days or so are 2 degree deep of healing
Burn face heals for 5 days or so, four limbs and healing in trunk 7-10 days or so, and 3 degree of small area are healed for burn 14 days or so, large area
3 degree burn 14-21 days or so heal, 3-4 degree severe burn through early stage debridement cut scab extend the dressing time can not have to make skin graft be cured
Close the surface of a wound)；
3. preventing from scar (scar tissue is not left in shallow 2 degree, deeply 2 degree burns generally)；
4. medicine yarn occlusive dressing nurses convenient (patient and entourage avoid direct contact with the surface of a wound)；
5. necrotic tissue reaches that debridement is thorough after following adherency medicine yarn when dressing, while utmostly reducing pain when dressing
Pain index).
6. raw material sources of the present invention are wide, preparation method is simple, and preparation cost is low, and curative effect is fast, takes effect, convenient transportation and storage
It deposits, therefore is with a wide range of applications.
Detailed description of the invention
Fig. 1 is the preparation technology figure of high-efficiency burn treating medicine.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the invention is clearly and completely described,
Obviously, the embodiment described is the embodiment of part of representative of the invention, rather than whole embodiments, this field are general
Other all embodiments obtained belong to protection of the invention to logical technical staff without making creative work
Range.
The preparation of 1 high-efficiency burn treating medicine of embodiment
Raw material composition：5 parts of corydalis tuber, 5 parts of the root of Dahurain angelica, 10 parts of Cortex Phellodendri, 5 parts of garden burnet, 10 parts of polygonum cuspidate, 5 parts of calamine, vaseline
800- parts, 40 parts of borneol.
Preparation method：Corydalis tuber, the root of Dahurain angelica, Cortex Phellodendri, garden burnet, polygonum cuspidate, calamine are beaten into powder, obtain mixed powder, crosses 100 mesh
Sieve；Borneol is added, 500W ultrasound 30min, 300r/min are stirred evenly, and vaseline is added, and are impregnated for 24 hours, are continued 300r/min and are stirred
It mixes uniformly, is placed at room temperature for 3 days to get high-efficiency burn treating medicine.
The preparation of 2 high-efficiency burn treating medicine of embodiment
Raw material composition：25 parts of corydalis tuber, 20 parts of the root of Dahurain angelica, 25 parts of Cortex Phellodendri, 15 parts of garden burnet, 25 parts of polygonum cuspidate, 20 parts of calamine, all scholars
1200 parts of woods, 80 parts of borneol.
Preparation method：Corydalis tuber, the root of Dahurain angelica, Cortex Phellodendri, garden burnet, polygonum cuspidate, calamine are beaten into powder, obtain mixed powder, crosses 150 mesh
Sieve；Borneol is added, 700W ultrasound 60min, 500r/min are stirred evenly, and vaseline is added, and impregnate 72h, are continued 500r/min and are stirred
It mixes uniformly, is placed at room temperature for 5 days to get high-efficiency burn treating medicine.
The preparation of 3 high-efficiency burn treating medicine of embodiment
Raw material composition：10 parts of corydalis tuber, 10 parts of the root of Dahurain angelica, 12 parts of Cortex Phellodendri, 8 parts of garden burnet, 13 parts of polygonum cuspidate, 7 parts of calamine, vaseline
900 parts, 45 parts of borneol.
Preparation method：Corydalis tuber, the root of Dahurain angelica, Cortex Phellodendri, garden burnet, polygonum cuspidate, calamine are beaten into powder, obtain mixed powder, crosses 100 mesh
Sieve；Borneol is added, 600W ultrasound 40min, 400r/min are stirred evenly, and vaseline is added, and impregnate 48h, are continued 400r/min and are stirred
It mixes uniformly, is placed at room temperature for 4 days to get high-efficiency burn treating medicine.
The preparation of 4 high-efficiency burn treating medicine of embodiment
Raw material composition：20 parts of corydalis tuber, 17 parts of the root of Dahurain angelica, 20 parts of Cortex Phellodendri, 15 parts of garden burnet, 20 parts of polygonum cuspidate, 18 parts of calamine, all scholars
1100 parts of woods, 70 parts of borneol.
Preparation method：Corydalis tuber, the root of Dahurain angelica, Cortex Phellodendri, garden burnet, polygonum cuspidate, calamine are beaten into powder, obtain mixed powder, crosses 150 mesh
Sieve；Borneol is added, 600W ultrasound 50min, 400r/min are stirred evenly, and vaseline is added, and impregnate 48h, are continued 400r/min and are stirred
It mixes uniformly, is placed at room temperature for 4 days to get high-efficiency burn treating medicine.
The preparation of 5 high-efficiency burn treating medicine of embodiment
Raw material composition：15 parts of corydalis tuber, 15 parts of the root of Dahurain angelica, 15 parts of Cortex Phellodendri, 15 parts of garden burnet, 15 parts of polygonum cuspidate, 15 parts of calamine, all scholars
1000 parts of woods, 60 parts of borneol.
Preparation method：Corydalis tuber, the root of Dahurain angelica, Cortex Phellodendri, garden burnet, polygonum cuspidate, calamine are beaten into powder, obtain mixed powder, crosses 100 mesh
Sieve；Borneol is added, 600W ultrasound 45min, 400r/min are stirred evenly, and vaseline is added, and impregnate 48h, are continued 400r/min and are stirred
It mixes uniformly, is placed at room temperature for 4 days to get high-efficiency burn treating medicine.
The preparation of 6 high-efficiency burn treating medicine yarn of embodiment
By 100 15X25cm2Single layer sterile gauze compacting, inner surface coating embodiment 5 prepare efficient burn and scald
Medicine, infrared baking, with tearable PE layers seal ointment part to get.
Typical case 1
Mr. Wang, female, 16 years old, Hunan Province Huaihua City people from Xinhua County.Once a basin boiled water was knocked down, so that left side buttocks, big
On rear side of leg and calf all scalds into big bubble by boiled water, and buttocks is most of for two degree or depth there are also exposing scarlet meat at two without skin
Degree scald.Gnawing pains take no rest, sweats all over.After coating drug of the present invention, relieve pain quickly.Bubble is bled off with anti-inflammatory needle.Daily two
It is secondary to smear drug of the present invention, it forms a scab within three days, fully recovers within ten days, become normal skin, without scar.
Typical case 2
Zhang, male, 30 years old, changde, hunan province city people from Hanshou county.In May, 2017, tricycle overturn, vehicle car boiled water water tank
It overturns, scalds waist, two arm rear portions, skin surface is all bubble, and it is two degree or depth scald that waist, which has without skin at two,.It applies
Upper ointment of the present invention and after giving enough anti-inflammatory and fluid infusion, fully recovers for 12 days.
Typical case 3
Zhao, male, 37 years old, Zhuzhou Smelter worker.On January 18th, 2018, because chemical drugs explode burn chest, abdomen,
Double lower limb body.Senseless, the blood strangury all over of patient's stupor at that time, it is believed that patient has breathing by gunpowder explosion death, immediately
It is rescued, Hemorrhagic shock processing, infusion is enriched blood, and shock carries out the treatment of medical fluid Chinese medicine lubricate after stablizing.Burn surface area up to 77%,
Wherein I degree 2%, shallow II degree 45%, deep II degree 25%, III degree 5%, after explosion, whole body eschar.The present inventor is small with medical fluid every 3
When it is 1 time spraying, the surface of a wound is coated on the surface of a wound with burn-scald medicine, after every dressing in 6 hours 1 time, 2 days, is wrapped up with burn-scald medicine yarn, 5 days
Surface of a wound eschar falls off afterwards, occurs within the 10th day skin island rapidly, fully recovers within deep the II degree surface of a wound the 13rd to 15 day, fullys recover from an illness within the III degree surface of a wound the 20th day
More, no scar contracture, full recovery after the 30th day, perspiration functions are good.
Those skilled in the art is not under conditions of departing from the spirit and scope of the present invention that claims determine, also
Various modifications can be carried out to the above content.Therefore the scope of the present invention is not limited in above explanation, but by
The range of claims determines.
Claims (10)
1. a kind of high-efficiency burn treating medicine, which is characterized in that be prepared by weight by following raw material：5-25 parts of corydalis tuber, the root of Dahurain angelica
5-20 parts, 10-25 parts of Cortex Phellodendri, 5-15 parts of garden burnet, 10-25 parts of polygonum cuspidate, 5-20 parts of calamine, 800-1200 parts of vaseline, borneol
40-80 parts.
2. a kind of high-efficiency burn treating medicine according to claim 1, which is characterized in that prepared by weight by following raw material and
At：It is 10-20 parts of corydalis tuber, 10-17 parts of the root of Dahurain angelica, 12-20 parts of Cortex Phellodendri, 8-15 parts of garden burnet, 13-20 parts of polygonum cuspidate, 7-18 parts of calamine, all
900-1100 parts of intellectual circle, 45-70 parts of borneol.
3. a kind of high-efficiency burn treating medicine according to claim 1, which is characterized in that prepared by weight by following raw material and
At：15 parts of corydalis tuber, 15 parts of the root of Dahurain angelica, 15 parts of Cortex Phellodendri, 15 parts of garden burnet, 15 parts of polygonum cuspidate, 15 parts of calamine, 1000 parts of vaseline, borneol
60 parts.
4. a kind of preparation method of high-efficiency burn treating medicine, which is characterized in that prepare in accordance with the following methods：By corydalis tuber, the root of Dahurain angelica, Huang
Cypress, garden burnet, polygonum cuspidate, calamine beat powder, obtain mixed powder, and borneol is added, and ultrasonic agitation uniformly, is added vaseline, impregnates 24-
72h continues to stir evenly, and is placed at room temperature for 3-5 days to get high-efficiency burn treating medicine.
5. a kind of preparation method of high-efficiency burn treating medicine according to claim 4, which is characterized in that the grain of the mixed powder
Diameter number is between 100-200 mesh.
6. a kind of preparation method of high-efficiency burn treating medicine according to claim 4, which is characterized in that the ultrasound condition is
500-700W ultrasound 30-60min.
7. a kind of preparation method of high-efficiency burn treating medicine according to claim 4, which is characterized in that the mixing speed is
300-500r/min。
8. a kind of high-efficiency burn treating medicine yarn, which is characterized in that the high-efficiency burn treating medicine yarn is wanted by any right of claim 1-3
It asks the high-efficiency burn treating medicine to be coated in gauze layer inner surface to be prepared.
9. a kind of high-efficiency burn treating medicine yarn according to claim 8, which is characterized in that the gauze is 15 × 25cm2Single layer
Sterile gauze.
10. a kind of high-efficiency burn treating medicine yarn according to claim 8, which is characterized in that the gauze layer is by 100 gauze pressures
It makes.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810979373.6A CN108853242A (en) | 2018-08-22 | 2018-08-22 | A kind of high-efficiency burn treating medicine and its preparation method and application |
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| CN201810979373.6A CN108853242A (en) | 2018-08-22 | 2018-08-22 | A kind of high-efficiency burn treating medicine and its preparation method and application |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112007262A (en) * | 2020-08-18 | 2020-12-01 | 南通市第二人民医院 | Burn orthopedics rehabilitation auxiliary coating device and use method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1297762A (en) * | 1999-11-29 | 2001-06-06 | 宗启海 | Burn treating liquid |
| CN102133340A (en) * | 2011-03-16 | 2011-07-27 | 四川同人泰药业有限公司 | Chinese herbal wound and burn patch for external use and preparation method thereof |
| CN102335309A (en) * | 2011-09-26 | 2012-02-01 | 张树臣 | Formula of ointment for treating burns and scalds |
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2018
- 2018-08-22 CN CN201810979373.6A patent/CN108853242A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1297762A (en) * | 1999-11-29 | 2001-06-06 | 宗启海 | Burn treating liquid |
| CN102133340A (en) * | 2011-03-16 | 2011-07-27 | 四川同人泰药业有限公司 | Chinese herbal wound and burn patch for external use and preparation method thereof |
| CN102335309A (en) * | 2011-09-26 | 2012-02-01 | 张树臣 | Formula of ointment for treating burns and scalds |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112007262A (en) * | 2020-08-18 | 2020-12-01 | 南通市第二人民医院 | Burn orthopedics rehabilitation auxiliary coating device and use method thereof |
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Application publication date: 20181123 |