CN112274556A - Spray for treating scalds and burns and preparation method thereof - Google Patents

Spray for treating scalds and burns and preparation method thereof Download PDF

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Publication number
CN112274556A
CN112274556A CN202010971768.9A CN202010971768A CN112274556A CN 112274556 A CN112274556 A CN 112274556A CN 202010971768 A CN202010971768 A CN 202010971768A CN 112274556 A CN112274556 A CN 112274556A
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spray
medicine
wound
wound surface
healing
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林仁川
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Engineering & Computer Science (AREA)
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  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a spray for treating scalds and burns and a preparation method thereof. The preparation method comprises the following steps: 1) selecting and cleaning; 2) soaking; 3) and (5) filtering and subpackaging. The spray has the effects of relieving swelling and pain, promoting blood circulation and nourishing blood, astringing dampness and healing sore, promoting granulation and healing wound, resisting bacteria and diminishing inflammation, relieving pain, protecting wound surfaces from infection and promoting wound healing. The external medicine fully stimulates the regeneration capability of human cells to promote the muscle tissue to grow again quickly, thereby achieving the treatment effect of short-term recovery. The application method is simple, and the medicine can be applied to the wound surface of a patient in a short time without treatment. The external medicine has more direct effect, simple dressing change and less pain, is beneficial to observing the change of the wound surface, and the medicine can keep the wound surface moist without leaving scars after healing, hormone and toxic and side effects on the medicine film formed on the wound surface. Can be used for treating burn, scald, ultraviolet radiation injury, and electric injury due to toxic heat.

Description

Spray for treating scalds and burns and preparation method thereof
Technical Field
The invention relates to the technical field of medical chemical industry, in particular to a spray for treating scalds and burns and a preparation method thereof.
Background
Burn and scald are caused by skin and muscle injury caused by external factors such as high temperature, radiation, strong light and the like, once the skin is damaged, the disease is rapidly attacked, if the skin cannot be treated in time, the mild people have erythema and water bubbles with different sizes, and the severe people have symptoms such as rot and suppuration.
The existing medicines for treating burns or scalds and the method thereof are mainly divided into the following categories: one kind is western medicine-based therapeutic medicine and therapeutic measures; one is a treatment route mainly based on traditional Chinese medicines; furthermore, the Chinese and western medicines are combined. The western medicine for treating burn is to treat the necrotic muscle tissue of the wound after cleaning and disinfecting the burn surface, then to wrap the wound, and the wound is mainly treated by internal medicines without any medicines. This approach appears scientific, does not actually slow down the pain of the patient very quickly, and is extremely expensive. One is the traditional Chinese medicine treatment route in China, namely on the basis of the theory of traditional Chinese medicine, the Chinese medicine has own knowledge and treatment measures for treating burn, and comprises folk compositions and the like. The formula of the invention is obtained by comprehensive development and research of folk proved formulas, and can effectively treat burns and scalds.
Disclosure of Invention
The invention aims to solve the problems in the background art and provides a spray for treating scalds and burns and a preparation method thereof.
In order to solve the technical problems, the technical scheme provided by the invention is as follows: a spray for treating scalds and burns comprises the following components in parts by weight: 100-300 parts of white spirit, 5-20 parts of red blueflower, 0.5-2 parts of radix sophorae flavescentis and 0.4-1.5 parts of cortex periplocae.
A preparation method of a spray for treating scalds and burns comprises the following steps:
1) selecting and cleaning: selecting high-quality red blueflower, radix sophorae flavescentis and cortex periplocae, cleaning impurities, and drying for later use;
2) soaking: adding the red blueflower, the radix sophorae flavescentis and the cortex periplocae into the white spirit, and soaking for 50-80 days;
3) and (3) filtering and subpackaging: sieving and filtering the mixture obtained in the step 2), subpackaging in a spray and bottling.
Compared with the prior art, the invention has the advantages that: the spray has the effects of relieving swelling and pain, promoting blood circulation and nourishing blood, astringing dampness and healing sore, promoting granulation and healing wound, resisting bacteria and diminishing inflammation, relieving pain, protecting wound surfaces from infection and promoting wound healing. The external medicine fully stimulates the regeneration capability of human cells to promote the muscle tissue to grow again quickly, thereby achieving the treatment effect of short-term recovery. The application method is simple, and the medicine can be applied to the wound surface of a patient in a short time without treatment. The external medicine has more direct effect, simple dressing change and less pain, is beneficial to observing the change of the wound surface, effectively retains moisture of a medicine film formed on the wound surface by the medicine, keeps the wound surface moist, does not leave scars after healing, has no hormone and has no toxic or side effect. Can be used for treating burn, scald, ultraviolet radiation injury, and electric injury due to toxic heat.
Detailed Description
Example 1
A spray for treating scalds and burns comprises the following components in parts by weight: 100 parts of white spirit, 5 parts of red blueflower, 0.5 part of radix sophorae flavescentis and 0.4 part of cortex periplocae.
A preparation method of a spray for treating scalds and burns comprises the following steps:
1) selecting and cleaning: selecting high-quality red blueflower, radix sophorae flavescentis and cortex periplocae, cleaning impurities, and drying for later use;
2) soaking: adding flos Carthami, radix Sophorae Flavescentis, and cortex Periplocae Radicis into Chinese liquor, and soaking for 50 days;
3) and (3) filtering and subpackaging: sieving and filtering the mixture obtained in the step 2), subpackaging in a spray and bottling.
Example 2
A spray for treating scalds and burns comprises the following components in parts by weight: 300 parts of white spirit, 20 parts of red blueflower, 2 parts of radix sophorae flavescentis and 1.5 parts of cortex periplocae.
A preparation method of a spray for treating scalds and burns comprises the following steps:
1) selecting and cleaning: selecting high-quality red blueflower, radix sophorae flavescentis and cortex periplocae, cleaning impurities, and drying for later use;
2) soaking: adding flos Carthami, radix Sophorae Flavescentis, and cortex Periplocae Radicis into Chinese liquor, and soaking for 80 days;
3) and (3) filtering and subpackaging: sieving and filtering the mixture obtained in the step 2), subpackaging in a spray and bottling.
Example 3
A spray for treating scalds and burns comprises the following components in parts by weight: 200 parts of white spirit, 10 parts of red blueflower, 1 part of radix sophorae flavescentis and 1 part of cortex periplocae.
A preparation method of a spray for treating scalds and burns comprises the following steps:
1) selecting and cleaning: selecting high-quality red blueflower, radix sophorae flavescentis and cortex periplocae, cleaning impurities, and drying for later use;
2) soaking: adding flos Carthami, radix Sophorae Flavescentis, and cortex Periplocae Radicis into Chinese liquor, and soaking for 60 days;
3) and (3) filtering and subpackaging: sieving and filtering the mixture obtained in the step 2), subpackaging in a spray and bottling.
Description of the cases
Case 1: chapter xx, male, 27 years old, burned with alcohol, area 78%, with superficial second degree burn 38%, deep second degree burn 25%, III degree burn 15%.
The clinical manifestations are as follows: the pain of the patient is intolerable, the patient can not feel well, the mind is clear, the breathing is short and thick, the pulse is slow, the head and the face are red, the fever and the blisters are broken, the exudation and the eluviation are dissolved, the blisters of the wound surface of the whole body are spread, the deep eschar color and the black state can be seen at the waist and the lower abdomen, the pain is not induced by plucking, the third-degree burn is caused, the deep second-degree burns are caused at the two sides of the hands and the thighs, the mild respiratory tract burn is accompanied, the dysphoria, the bitter taste.
The treatment process comprises the following steps: the wound surface is cleaned by using normal saline and 1% benzalkonium chloride solution urgently, water bubbles are repaired, the original medicine and the oil preparation are quickly distributed to relieve pain stimulation, shock is prevented, a patient feels cool all over the body immediately, the pain is greatly reduced, meanwhile, fluid infusion is given to resist shock and infection, the swelling on the face is relieved after three days, the general edema is relieved after seven days, shallow II-degree burn is healed, the face scab is formed, deep II-degree burn is well scabbed without infection, III-degree burn wound surface scabs after ten days, III-degree burn wound surface new tissues are formed after fifteen days, the other parts except small-area compression parts are healed, the activities are performed in parallel, the function exercise is strengthened, the wound surface is automatically discharged after twenty-five days, the wound surface is returned to the hospital after one month, and no sequelae is generated.
Case 2: plum xx, male, 37 years old, and workers in a certain chemical plant burn the back, the hip, the upper limb, the lower limb, the hand and the leg of a plurality of places due to accident with concentrated sulfuric acid, and the affected area is changed to our hospital after 20 days of treatment in the hospital, the wound surface forms deep III-degree ulcer, the total area is 25%, the ulcer area is 20%, and the right side of the toe bone is exposed.
The clinical manifestations are as follows: the periphery of the wound surface is red and swollen, purulent secretion of the ulcer surface has blood exudation, and the ulcer surface is completely chemical concentrated sulfuric acid rotten deep ulcer, has intolerable pain, can not fall asleep, withers and rubs, has low language, shallow breath, clear spirit, weak pulse, cold sweat and pale complexion at the body temperature of 37-39 ℃. It is also known as asthenia due to exudation and hemorrhage.
The treatment process comprises the following steps: the wound surface is cleaned in time, the mixture is respectively used for spreading ulcer surfaces with the detoxification medicine to relieve pain, stop bleeding, astringe, remove blood stasis and detoxify, namely, the mixture is used for fluid infusion and anti-shock, and the traditional Chinese medicine Xiaochaihu decoction and Xiaoxianxiong decoction are added to lower the temperature, control inflammation and prevent collapse treatment. After the medicine is taken, the patient feels cool and relaxed immediately, the pain is relieved, and the patient sleeps deep and calmly in the evening. After three days, the exudation of the wound surface is reduced, medicinal scab begins to form, the spirit of the patient is improved, the patient starts to eat, the sound is loud and bright, the wound surface is exposed, the medicinal scab is protected, and the wound surface is healed smoothly. The exposed phalanges are closed after follow-up visit, scars grow and the functions are affected to a certain extent, and the scars are removed after the application of the scar treatment medicine, and no other sequelae appear.
Case 3: wanxxx, female, 25 years old, head, neck, hands, forearms, elbows, area burned by liquefied gas 26%, III degree burn 6%, deep II degree burn 8%, superficial II degree burn 13%.
The clinical manifestations are as follows: swollen head and face, invisible eyes, inability to open mouth, inability to bend and stretch hands and arms, mild respiratory tract burn, black epidermis, exudation and edema of wound surface, infection due to puncture of three glass parts, 39-40 ℃ of body temperature, severe fever at night, thirst, polydipsia, mania, uneasiness, aversion to cold, sweating, severe pain, and sometimes obnubilation, shortness of breath, red tongue and descending of the back, dark urine, constipation, inability to get in food, invasion of fire toxin, and heat injury to the ying-defensive system.
The treatment process comprises the following steps: the original medicine and the oil preparation are distributed immediately, patients feel cool and relaxed immediately, pain is reduced, anti-inflammatory fluid infusion treatment is given subsequently, the ginseng decoction and the coptis toxin expelling decoction are taken orally, swelling and body temperature decrease are started after 36 hours, heat and swelling are relieved after three days, no seepage exists, eyes open and eat, eschar and dryness exist in five days, escharosis starts in seven days, eschar and falls on the eyes, medicine eschar and falls on 10 days, no pain and discomfort exist, the wound surface is not scarred after healing, the wound surface is released to hospital after 10 days, the hospital returns to the hospital after one month, the skin color of the wound surface is recovered, the new skin is compact, elastic, smooth and soft, hair grows normally, and no sequela exists.

Claims (2)

1. The spray for treating scalds and burns is characterized by comprising the following components in parts by weight: 100-300 parts of white spirit, 5-20 parts of red blueflower, 0.5-2 parts of radix sophorae flavescentis and 0.4-1.5 parts of cortex periplocae.
2. A preparation method of a spray for treating scalds and burns is characterized by comprising the following steps:
1) selecting and cleaning: selecting high-quality red blueflower, radix sophorae flavescentis and cortex periplocae, cleaning impurities, and drying for later use;
2) soaking: adding the red blueflower, the radix sophorae flavescentis and the cortex periplocae into the white spirit, and soaking for 50-80 days;
3) and (3) filtering and subpackaging: sieving and filtering the mixture obtained in the step 2), subpackaging in a spray and bottling.
CN202010971768.9A 2020-09-16 2020-09-16 Spray for treating scalds and burns and preparation method thereof Pending CN112274556A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114159508A (en) * 2022-01-11 2022-03-11 广东安道医疗器械有限公司 Preparation method of calyx seu fructus physalis refined product for treating wound healing and scald

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031081A (en) * 2015-06-25 2015-11-11 当涂县科辉商贸有限公司 Orally-administrated traditional Chinese medicine capable of treating burns and scalds
CN108392535A (en) * 2017-05-10 2018-08-14 刘保海 A kind of burn and scald sprayer formulation and preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031081A (en) * 2015-06-25 2015-11-11 当涂县科辉商贸有限公司 Orally-administrated traditional Chinese medicine capable of treating burns and scalds
CN108392535A (en) * 2017-05-10 2018-08-14 刘保海 A kind of burn and scald sprayer formulation and preparation method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114159508A (en) * 2022-01-11 2022-03-11 广东安道医疗器械有限公司 Preparation method of calyx seu fructus physalis refined product for treating wound healing and scald

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