CN102824495B - Traditional Chinese medicine ointment for treating bedsore in clinical care and preparation method of ointment - Google Patents
Traditional Chinese medicine ointment for treating bedsore in clinical care and preparation method of ointment Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine ointment for treating bedsore in clinical care and a preparation method of the traditional Chinese medicine ointment, belonging to the field of traditional Chinese medicine. The active ingredients of the traditional Chinese medicine ointment provided by the invention comprise the raw materials in parts by weight: 20-40 parts of nux vomica, 20-40 parts of pinellia ternate, 15-30 parts of the root of red-rooted salvia, 15-30 parts of periostracum cicada, 15-30 parts of cuttlebone, 10-20 parts of pseudo-ginseng, 10-20 parts of gentiana macrophylla, 15-30 parts of puffball, 12-18 parts of camphor, 10-20 parts of garden burnet, 15-30 parts of mother chrysanthemum and 12-16 parts of setose thistle. The traditional Chinese medicine ointment provided by the invention has the functions of astringing dampness, regenerating tissue and healing wound, can improve the blood circulation of the pressed tissues of the long-term bedridden patients, can be used for various mild, moderate and severe bedsores, and can quickly fight bacterium and diminish inflammation, remove the necrotic tissue and regenerate the tissue, break the stasis and stimulate the menstrual flow, astringe the boils and reduce the swelling after being externally applied to a bedsore part, and can be used for repairing the skin tissue. The clinical trial shows that the traditional Chinese medicine ointment is quick in curative effect, good in effect, safe and reliable and free from toxic and side effects, and can obviously treat the bedsore at different stages.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of clinical care Chinese medicinal ointment for the treatment of decubital ulcer and preparation method thereof.
Background technology
Decubital ulcer another name " pressure skin ulcer ", " pressure ulcer ".Decubital ulcer is the long-term pressurized of body part, makes blood circulation be subject to obstacle, causes that skin and subcutaneous tissue because of ischemia vesicle occur, ulcer or gangrene.Generally speaking, decubital ulcer is owing to the latter stage result of nutrition blood confession with body tissue generation circulatory disorders.
How due to illness decubital ulcer paralysis, and long-term bed body constitution is depleted, lies in bed with the passing of time, and it is improper to nurse, and stands up the patient Yi Fasheng of movable inconvenience and limbs sensory disturbance.Excessively become thin, obesity, edema, arteriosclerosis all easily impel decubital ulcer to form.Redness and blister appear in the early stage visible local skin of patient, become later on aubergine and begin ulceration, and ulceration primary sore face is scarlet transudate, and then the skin ulcer face is deepened, the colour-darkening blackout.Be apt to occur in the receptor weight such as thoracic dorsal, buttocks, hip joint, heel and external malleolus and compel the place.There are approximately 60,000 people to die from the decubital ulcer complication every year according to the related documents report.According to the evolution of decubital ulcer, light and heavy degree is different, can be divided into for three phases: the ruddy phase of (one) congestion, the local skin pressurized or be subjected to moist the stimulation after, red, swollen, hot, numbness or tenderness appear, the nothing that the has thermal response that swells.(2) the inflammatory infiltration phase, if red and swollen section continues pressurized, blood circulation can not get improving, and the pressure surface color of the leather transfers to purplish red, and skin vesicle occurs because of the edema attenuation, and this moment is ulceration very easily, manifests moist ruddy wound surface.(3) ulcerative stage, venous backflow is subject to serious hindrance, and local congestion hyperamization bolt forms, the tissue ischemia anoxia.The lighter shallow layer tissue infects, and pus flows out, ulcer; Severe one slough blackout, purulent secretion increases, frowziness.Infect reaching towards periphery the deep expansion, can reach skeleton, even cause septicemia.
Clinical treatment mainly is that anti-inflammation is main at present, prevent secondary infection, but this class medicine has stronger zest to wound surface, easy damaged new granulation tissue when changing dressings, be unfavorable for the healing of wound surface, the therefore rapid granulation promoting open sore part that heals is so clinical efficacy is unsatisfactory.So far, there is no comparatively desirable medicine and method both at home and abroad.
Summary of the invention
The invention provides a kind of clinical care Chinese medicinal ointment for the treatment of decubital ulcer and preparation method thereof, Chinese medicinal ointment of the present invention is evident in efficacy, clinical recovery fast and be difficult for recurrence, without any side effects, can make fast and effectively the healing of decubitus ulcer face, remove patient's misery, alleviated nursing staff's labor intensity.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A kind of clinical care with the Chinese medicinal ointment for the treatment of decubital ulcer, raw material composition and the parts by weight of making described Chinese medicinal ointment effective ingredient is:
15～30 parts of 15～30 portions of Periostracum Cicadaes of 20～40 parts of Radix Salviae Miltiorrhizaes of 20～40 parts of Rhizoma Pinelliaes of Semen Strychni
15～30 parts of 10～20 parts of Lasiosphaera Seu Calvatia of sea 10～20 portions of Radix Gentianae Macrophyllae of 15～30 portions of Radix Notoginseng of Piao sheath
12～16 parts of 15～30 portions of Radix Cirsii Japonicis of 10～20 parts of Flos Chrysanthemi Indicis of 12～18 portions of Radix Sanguisorbaes of Camphora.
Raw material composition and the parts by weight of making described Chinese medicinal ointment effective ingredient are:
20 parts of 25 portions of Periostracum Cicadaes of 35 parts of Radix Salviae Miltiorrhizaes of 32 parts of Rhizoma Pinelliaes of Semen Strychni
22 parts of 15 parts of Lasiosphaera Seu Calvatia of sea 15 portions of Radix Gentianae Macrophyllae of 20 portions of Radix Notoginseng of Piao sheath
14 parts of 20 portions of Radix Cirsii Japonicis of 12 parts of Flos Chrysanthemi Indicis of 16 portions of Radix Sanguisorbaes of Camphora.
A kind of clinical care preparation method of the Chinese medicinal ointment for the treatment of decubital ulcer comprises following processing step:
(1) Semen Strychni, the Rhizoma Pinelliae, Radix Salviae Miltiorrhizae, Periostracum Cicadae, extra large Piao sheath, Radix Notoginseng, Radix Gentianae Macrophyllae, Lasiosphaera Seu Calvatia, Camphora, Radix Sanguisorbae are mixed, carry out pulverization process behind the mix homogeneously, porphyrize is crossed 600 order fine powders, and is for subsequent use.
(2) Flos Chrysanthemi Indici and Radix Cirsii Japonici are added in the container, add the water of 6 times of amounts, extracted 2 hours, filter taking liquid; The water that adds again 4 times of amounts in remaining residue extracted 1 hour, filtered taking liquid; Merge medicinal liquid twice, be condensed into relative density and be 1.40～1.45 thick paste, drying under reduced pressure.
(3) gained fine powder in the step (1) is added step (2) and make mix homogeneously in the thick paste, after 55 ℃ of dryings, be ground into 600 purpose medicated powder, be mixed and made into paste with adjuvant and get final product.
Described adjuvant is Oleum Brassicae campestris, and the weight ratio of medicated powder and Oleum Brassicae campestris is 3: 11.
The property of medicine of the used Chinese medicine of the present invention is as follows:
Semen Strychni: hardship, cold, poisonous.Return liver, spleen two warps.The effect that removing obstruction in the collateral to relieve pain, dispersing swelling and dissipating binds are arranged.With controlling wound pain caused by ecchymoma and ulcer sore pain." Chinese medicinal herbal " carries: " loose heat in blood, detumescence poison.Control carbuncle, malignant boil.”
The Rhizoma Pinelliae: suffering, temperature, poisonous.Enter spleen, stomach warp.Drying dampness to eliminate phlegm is arranged, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, the effect of outer subduing inflammation." property of medicine opinion " carries: " new survivor rubs and is coated with carbuncle and does not disappear, and can remove the tumor wart.”
Radix Salviae Miltiorrhizae: hardship, tepor.Enter the heart, Liver Channel.Promoting blood flow to regulate menstruation is arranged, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, the effect of nourishing blood to tranquillize the mind." Japan hanako materia medica " carries: " the evacuation of pus pain relieving, granulation promoting is put on flesh; Broken stagnated blood is mended new hemopoietic.”
Periostracum Cicadae: sweet, cold.Return lung, Liver Channel.Loose wind heat extraction is arranged, sore-throat relieving, rash, nebula removing, the effect of spasmolytic." detailed outline " carries: " control phlegm-accumulating vertigo, the skin wind heat, varioliform exanthema is had an itch, tetanus and treatment toxic swelling skin ulcer.”
Sea Piao sheath: salty, tepor.Return spleen, kidney channel.Dehumidifying is arranged, antacid, hemostasis, the effect of sore." not Lu " carries: " frightened gas enters abdomen, stomachache ring umbilicus, and edema due to cold pathogen in the moon, it is not dry to end again the many pus of skin ulcer.”
Radix Notoginseng: sweet in the mouth; Little hardship; Warm in nature.Return Liver Channel, stomach warp, heart channel, lung meridian, large intestine channel.Hemostasis is arranged, loose blood, the effect of analgesic therapy." Records of Tradition Chinese and Western Medicine in Combination " carries: " external is apt to control incised wound, applies wound with its end, vertical can healing by blood and relieving pain." cloud again: " poison of all skin ulcers is bone person goes out also outside all available Radix Notoginseng holder.”
Radix Gentianae Macrophyllae: hot, bitter, be slightly cold.Return stomach warp, Liver Channel, gallbladder meridian.Wind-damp dispelling is arranged, Shujin network, the effect of clearind deficient heat." Renzhai Zhi Zhi Fang, Effective Recipes from Renzhai House " carries: " control ulcerous nonunion, Radix Gentianae Macrophyllae is that it is mixed in the end.”
Lasiosphaera Seu Calvatia: hot, flat, nontoxic.Return lung meridian.Removing heat from the lung and relieving sorethroat is arranged, detoxifcation, the effect of hemostasis." not Lu " carries: " main malignant boil, prurigo.”
Camphora: hot, heat, poisonous.GUIXIN, spleen channel.The dehumidifying parasite killing is arranged, and warming and odynolysis is had one's ideas straightened out and is warded off dirty effect." Prescriptions for Universal Relief " carries: " control all malignant boil and beat as cream and pounce on damage, the diseases such as rheumatism beriberi.”
Radix Sanguisorbae: picric acid; Cold; Nontoxic.Return liver, lung, kidney, large intestine channel.Cooling blood for hemostasis is arranged, heat-clearing and toxic substances removing, the effect of detumescence sore." not Lu " carries: " end pus and blood, all flaccidity, malignant boil, the wine that disappears except quenching one's thirst, is mended absolutely and is hindered, and plug can be made incised wound cream in puerperal.”
Flos Chrysanthemi Indici: hot, bitter.Return lung, Liver Channel.Heat-clearing and toxic substances removing is arranged, the effect of dispelling wind suppressing the hyperactive liver.Can treat furuncle; Carbuncle; Erysipelas; Eczema; Dermatitis; Anemopyretic cold; Laryngopharynx swelling and pain; Hypertension." Zhejiang Chinese medicine handbook is carried: " promoting pus discharge and removing toxic substances, reducing swelling and alleviating pain.Control carbuncle and treat poison, day bleb eczema.”
Radix Cirsii Japonici: cool in nature, sweet in the mouth, hardship, nontoxic.GUIXIN, Liver Channel.Can treat acute appendicitis, carbuncle and ulcer toxic swelling, furuncle." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " repercussive blood, tissue regeneration promoting blood, the sore that disappears, loose scrofula tuberculosis, for a long time not closing in of carbuncle sore person, granulation promoting evacuation of pus.”
Semen Strychni, the Rhizoma Pinelliae, Radix Sanguisorbae, Radix Cirsii Japonici have the effect of removing obstruction in the collateral to relieve pain, dispersing swelling and dissipating binds in the prescription of the present invention; Radix Salviae Miltiorrhizae, Periostracum Cicadae have the effect of stasis-dispelling and pain-killing, loose wind heat extraction; Sea Piao sheath has the effect of hemostasis, sore; Radix Notoginseng has the effect of blood circulation promoting and blood stasis dispelling, pain relieving; Radix Gentianae Macrophyllae, Lasiosphaera Seu Calvatia, Camphora, Flos Chrysanthemi Indici have the effect of the loose Shujin of temperature, heat-clearing and toxic substances removing; Add again the Oleum Brassicae campestris modulation, can soften wound surface, promote the absorption of Chinese medicinal ointment.
Chinese medicinal ointment of the present invention has the effect of removing dampness promoting tissue regeneration and ulcer healing, can improve the blood circulation of patient bedridden in long term pressurized tissue, can be used for various light severe bedsores; By external application decubital ulcer position, the quick antibacterial antiinflammatory, removing the necrotic tissue and promoting granulation, removing blood stasis stimulates the menstrual flow, healing up sore and subduing swelling is repaired skin tissue, and clinical experiment shows that Chinese medicinal ointment curative effect of the present invention is fast, effective, safe and reliable, have no side effect, the decubital ulcer of each phase all there is obvious therapeutic effect.
Using method is first with povidone iodine or alcohol disinfecting periphery skin, then Chinese medicinal ointment is applied in the affected part with cotton swab, then with gauze ointment is covered, in order to avoid make dirty clothes or bedding are coated with 3 every day, 5 days is a course for the treatment of.Slight patient can fully recover a course for the treatment of, for heavier needs of patients two to three courses for the treatment of.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicinal ointment effective ingredient of the present invention forms and weight is:
Semen Strychni 32g Rhizoma Pinelliae 35g Radix Salviae Miltiorrhizae 25g Periostracum Cicadae 20g
Sea Piao sheath 20g Radix Notoginseng 15g Radix Gentianae Macrophyllae 15g Lasiosphaera Seu Calvatia 22g
Camphora 16g Radix Sanguisorbae 12g Flos Chrysanthemi Indici 20g Radix Cirsii Japonici 14g.
The processing step of Chinese medicinal ointment preparation method of the present invention is:
(1) Semen Strychni, the Rhizoma Pinelliae, Radix Salviae Miltiorrhizae, Periostracum Cicadae, extra large Piao sheath, Radix Notoginseng, Radix Gentianae Macrophyllae, Lasiosphaera Seu Calvatia, Camphora, Radix Sanguisorbae are mixed, carry out pulverization process behind the mix homogeneously, porphyrize is crossed 600 order fine powders, and is for subsequent use.
(2) Flos Chrysanthemi Indici and Radix Cirsii Japonici are added in the container, add the water of 6 times of amounts, extracted 2 hours, filter taking liquid; The water that adds again 4 times of amounts in remaining residue extracted 1 hour, filtered taking liquid; Merge medicinal liquid twice, be condensed into relative density and be 1.40～1.45 thick paste, drying under reduced pressure.
(3) gained fine powder in the step (1) is added step (2) and make mix homogeneously in the thick paste, after 55 ℃ of dryings, be ground into 600 purpose medicated powder, be mixed and made into paste with adjuvant and get final product.
Described adjuvant is Oleum Brassicae campestris, and the weight ratio of medicated powder and Oleum Brassicae campestris is 3: 11.
Embodiment 2
The raw material of Chinese medicinal ointment effective ingredient of the present invention forms and weight is:
Semen Strychni 36g Rhizoma Pinelliae 38g Radix Salviae Miltiorrhizae 27g Periostracum Cicadae 25g
Sea Piao sheath 22g Radix Notoginseng 16g Radix Gentianae Macrophyllae 16g Lasiosphaera Seu Calvatia 25g
Camphora 17g Radix Sanguisorbae 15g Flos Chrysanthemi Indici 24g Radix Cirsii Japonici 15g.
The Chinese medicinal ointment preparation method processing step of present embodiment is identical with embodiment 1.
Described adjuvant is Oleum Brassicae campestris, and the weight ratio of medicated powder and Oleum Brassicae campestris is 3: 11.
Embodiment 3
The raw material of Chinese medicinal ointment effective ingredient of the present invention forms and parts by weight are:
Semen Strychni 25g Rhizoma Pinelliae 25g Radix Salviae Miltiorrhizae 20g Periostracum Cicadae 18g
Sea Piao sheath 18g Radix Notoginseng 12g Radix Gentianae Macrophyllae 12g Lasiosphaera Seu Calvatia 17g
Camphora 14g Radix Sanguisorbae 11g Flos Chrysanthemi Indici 18g Radix Cirsii Japonici 13g.
The Chinese medicinal ointment preparation method processing step of present embodiment is identical with embodiment 1.
Described adjuvant is Oleum Brassicae campestris, and the weight ratio of medicated powder and Oleum Brassicae campestris is 3: 11.
Clinical data:
1, physical data
Select my inpatient of institute 128 routine clinical observations, male 68 examples, women 60 examples; 9～72 years old age, mean age, 38.6 years old; Bed reason: cerebral trauma 39 examples of going into a coma, traumatic paralysis 25 examples, hemiplegia 64 examples that cerebrovascular causes; Decubital ulcer position: sacrococcygeal region 86 examples, back 29 examples, heel portion 13 examples; Decubital ulcer area: the maximum 12.3cm of diameter, minimum 5.7cm.The most shallow to subcutis, the deeplyest see that rumpbone or calcaneus are local and expose.
2, Therapeutic Method
Patient first with povidone iodine or alcohol disinfecting periphery skin, then is applied in the affected part with Chinese medicinal ointment with cotton swab, then with gauze ointment is covered, in order to avoid make dirty clothes or bedding are coated with 3 every day, 5 days is a course for the treatment of.
3, curative effect determinate standard
(1) recovery from illness: the ulcer incrustation also comes off, and local organization is repaired fully.
(2) take a turn for the better: ulcer area is dwindled, the granulation tissue well-grown, and the wound surface recovery from illness reaches more than 50%.
(3) invalid: the granulation tissue undergrowth, wound surface is without the healing sign.
4, therapeutic outcome statistics
After two course of therapy, 89 examples of fully recovering, 36 examples that take a turn for the better, invalid 3 examples, total effective rate reaches 97.7%.
Model case is given an example:
1, the Wei * *, woman, 68 years old, retired worker.4 years prolapse carbuncle in the occipital region hemorrhages are though through rescuing Survive the perils of life, stay sequela and be paralyzed in bed, can't take care of oneself at all, found decubital ulcer ill later six months, begin treatment immediately, but therapeutic effect is not obvious, and the wound surface scope of heel parts and buttocks enlarges gradually, hurt like hell uses Chinese medicinal ointment of the present invention after 2 days, and pain symptom obviously alleviates, wound surface grows new granulation and begins and healing occurs, fully recovers after two courses for the treatment of.
2, horse * *, man, 35 years old, builder.Industrial accident occurs when work in the building site, cause and fracture the right legs, fix with Gypsum Fibrosum, find when removing Gypsum Fibrosum after 20 days that the erythema decubitus symptom appears in right inboard leg, disinfect in alcohol immediately, smear Chinese medicinal ointment of the present invention, even be coated with 3 days, decubitus symptom disappears.
3, Pueraria lobota * *, woman, 43 years old, the employee of public institution.Because of accident, the brain injury stupor, in the while in hospital, the erythema lump appears in back and shank, is diagnosed as decubital ulcer, smears immediately Chinese medicinal ointment of the present invention, smears continuously 3 days, and transference cure is revived after 20 days in hospital, until be discharged from hospitals upon recovery, decubitus symptom do not occur.
4, woods * *, man, 59 years old, peasant.Due to illness long-term bed, because skin is oppressed for a long time, skin can not get the normal keeping of blood, and decubital ulcer appears in patient's sacrococcygeal region, skin ulceration, wound surface is darker, and slough covers, the adularescent exudate, the flavor that gives out a foul smell, after using Chinese medicinal ointment of the present invention to smear two courses for the treatment of, wound healing, patient skin do not stay any sequela.
Claims (4)
1. a clinical care is characterized in that with the Chinese medicinal ointment for the treatment of decubital ulcer: the raw material of making described Chinese medicinal ointment effective ingredient forms and parts by weight are:
15～30 parts of 15～30 portions of Periostracum Cicadaes of 20～40 parts of Radix Salviae Miltiorrhizaes of 20～40 parts of Rhizoma Pinelliaes of Semen Strychni
15～30 parts of 10～20 parts of Lasiosphaera Seu Calvatia of sea 10～20 portions of Radix Gentianae Macrophyllae of 15～30 portions of Radix Notoginseng of Piao sheath
12～16 parts of 15～30 portions of Radix Cirsii Japonicis of 10～20 parts of Flos Chrysanthemi Indicis of 12～18 portions of Radix Sanguisorbaes of Camphora.
2. a kind of clinical care usefulness according to claim 1 is treated the Chinese medicinal ointment of decubital ulcer, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicinal ointment effective ingredient are:
20 parts of 25 portions of Periostracum Cicadaes of 35 parts of Radix Salviae Miltiorrhizaes of 32 parts of Rhizoma Pinelliaes of Semen Strychni
22 parts of 15 parts of Lasiosphaera Seu Calvatia of sea 15 portions of Radix Gentianae Macrophyllae of 20 portions of Radix Notoginseng of Piao sheath
14 parts of 20 portions of Radix Cirsii Japonicis of 12 parts of Flos Chrysanthemi Indicis of 16 portions of Radix Sanguisorbaes of Camphora.
3. a clinical care is characterized in that: comprise following processing step with the preparation method of the Chinese medicinal ointment for the treatment of decubital ulcer:
(1) Semen Strychni, the Rhizoma Pinelliae, Radix Salviae Miltiorrhizae, Periostracum Cicadae, extra large Piao sheath, Radix Notoginseng, Radix Gentianae Macrophyllae, Lasiosphaera Seu Calvatia, Camphora, Radix Sanguisorbae are mixed, carry out pulverization process behind the mix homogeneously, porphyrize is crossed 600 order fine powders, and is for subsequent use;
(2) Flos Chrysanthemi Indici and Radix Cirsii Japonici are added in the container, add the water of 6 times of amounts, extracted 2 hours, filter taking liquid; The water that adds again 4 times of amounts in remaining residue extracted 1 hour, filtered taking liquid; Merge medicinal liquid twice, be condensed into relative density and be 1.40～1.45 thick paste, drying under reduced pressure;
(3) gained fine powder in the step (1) is added step (2) and make mix homogeneously in the thick paste, after 55 ℃ of dryings, be ground into 600 purpose medicated powder, be mixed and made into paste with adjuvant and get final product.
4. preparation method according to claim 3, it is characterized in that: described adjuvant is Oleum Brassicae campestris, the weight ratio of medicated powder and Oleum Brassicae campestris is 3: 11.
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| Title |
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| 《中药在压疮治疗中的应用进展》;吴建霞等;《中国中医药信息杂志》;20111231;第18卷(第12期);103-106 * |
| 《复方黄马酊治疗褥疮17例》;龙雪;《实用中医药杂志》;20101031;第26卷(第10期);713 * |
| 吴建霞等.《中药在压疮治疗中的应用进展》.《中国中医药信息杂志》.2011,第18卷(第12期),103-106. |
| 龙雪.《复方黄马酊治疗褥疮17例》.《实用中医药杂志》.2010,第26卷(第10期),713. |
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