CN105362437A - Prescription of medical ointment for treating decubitus, and preparation method for medical ointment - Google Patents
Prescription of medical ointment for treating decubitus, and preparation method for medical ointment Download PDFInfo
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Abstract
The invention provides a prescription of medical ointment for treating decubitus, and a preparation method for the medical ointment. The preparation method comprises the following steps: respectively cleaning 120 parts of coptis chinensis, 120 parts of cortex phellodendri, 120 parts of astragalus membranaceus, 120 parts of radix sanguisorbae, 100 parts of rhubarb roots, 100 parts of giant knotweed and 80 parts of radix arnebiae, pulverizing the herbs into 100-mesh fine powder, adding the powder into 10,000 parts of pure balm for soaking for 48 hours, decocting the soaked herbs and pure balm with big fire till the mixture to be boiled, then using slow fire for decoction after boiling, and stopping decoction till the oil liquid becomes golden yellow, and filtering herb residues to obtain a medical oil; after the medical oil is cooled to be 80 DEG C, uniformly pouring pulverized 50 parts of olibanum, 50 parts of myrrh, 50 parts of borneol and 20 parts of 654-2 into the decocted medical oil to be uniformly mixed, and then adding liquid paraffin to adjust the ointment to enable the consistency of the ointment to be suitable for application, so as to obtain the medical ointment. The medical ointment can prevent wound contamination, so that the possibility of wound scabbing is low, pain of an ulcer patient is relieved, and aims at body surface damage caused by skin breakage ulcer diseases as human skin is under the compression for a long time.
Description
Technical field
The present invention relates to a kind of medicine ointment compositions for the treatment of decubital ulcer, belong to the field of Chinese medicines.Particularly a kind of medicine ointment prescription and preparation method for the treatment of decubital ulcer disease.This prescription causes the body-surface rauma caused by skin injury ulcer diseases mainly for the long-time pressurized of human body skin, the damage of namely usually alleged decubital ulcer or other infringement body surfaces.
Background technology
Decubital ulcer is a kind of commonly encountered diseases, clinically show as complication more, mainly because long-term bed causes, often bring great misery to patient, and wound easy infection, not easily heal, the physical and mental health of patient in serious threat, on it, normally work and life cause serious impact.Have a lot of stroke patient physical palsy and postoperative patient to need long-term bed at treatments period, the incidence rate of decubital ulcer is very high.The ointment of current treatment decubital ulcer is a lot, but large be main mainly with anti-inflammatory analgetic, thoroughly can not be effected a radical cure, therapeutic effect be not very satisfactory.In addition, because decubital ulcer can not get effective treatment, considerably increase nursing work load, also can affect the treatment that patient suffers from the disease.Though have multi-medicament to treat decubital ulcer at present, alleviate patient suffering, shorten treatment time and reduce sequela aspect and also have certain curative effect, but the difference of composition and the difference of Therapeutic Method contained by often kind of medicine, cause it to the therapeutic effect of a lot of patient and unsatisfactory, be such as difficult to quickly alleviating pain, healing time long, leave cicatrix etc. more afterwards.
Summary of the invention
The object of the invention is for prior art not enough, one is provided to treat decubital ulcer medicine ointment prescription and preparation method thereof, this ointment can quickly alleviating pain, short treating period, instant effect, high safety, bedsore wound repair effect good, cure after cicatrix few, have no side effect, be applicable to various skin injury ulcer diseases, and the medicine for external use ointment of the Wound treating such as skin ulceration, pressure ulcer, burn.
One of the present invention treat decubital ulcer medicine ointment by weight prescription be:
Rhizoma Coptidis 120 parts, Cortex Phellodendri 100 parts, the Radix Astragali 120 parts, Radix Sanguisorbae 120 parts, Radix Rumicis 100 parts, Rhizoma Polygoni Cuspidati 100 parts, Radix Arnebiae (Radix Lithospermi) 80 parts, Olibanum 50 parts, Myrrha 50 parts, Borneolum Syntheticum 50 parts, 654-2 are 20 parts, Oleum sesami 10000 parts, liquid paraffin consistency modifiers;
A kind of preparation method for the treatment of external application bedsore drug ointment of the present invention is:
By Rhizoma Coptidis 120 parts, Cortex Phellodendri 120 parts, the Radix Astragali 120 parts, Radix Sanguisorbae 120 parts, Radix Rumicis 100 parts, Rhizoma Polygoni Cuspidati 100 parts, Radix Arnebiae (Radix Lithospermi) 80 parts, clean up respectively after, be ground into 100 object fine powders to join in 10000 parts of pure sesame oils and soak after 48 hours, again the medicine of immersion and pure sesame oil big fire are boiled to boiling, slow fire boiling is used instead again, until fluid is rendered as golden yellow can stop decoction, elimination medicinal residues after boiling; To be cooledly pour into equably to decoct in well-done medicine oil after mixing to when 80 degree by the Olibanum 50 parts crushed, Myrrha 50 parts, Borneolum Syntheticum 50 parts, 654-2 being 20 parts, add the denseness that liquid paraffin regulating ointment is applicable to applying again, obtain medicine ointment, after waiting cooling, sterile filling is stand-by.
Beneficial effect of the present invention: the present invention compared with prior art has the following advantages: medicine of the present invention smears wound with ointment form or spread upon dressing (gauze) to stick in wound surface, it forms a kind of oiliness isolating membrane barrier, reduce the water evaporates of wound surface thus, and can prevent wound surface from polluting.Meanwhile, it not easily makes wound surface form a scab, wound fluid easily with the mixing mutually of (oil preparation sand cloth), be conducive to wound surface drain, therefore significantly reduce the misery of ulcers.Its medicine ointment prescription all has heat-clearing and toxic substances removing, skin ulcer, blood circulation promoting and blood stasis dispelling, convergence pain relieving are controlled in detumescence, effect that putrefaction-removing granulation-promoting is antipruritic, it can promote wound surface local blood circulation clinically, alleviate wound surface local swelling, therefore be conducive to the growth of the recovery of wound surface blood stasis and stagnant zone, the coming off of slough, epithelial tissue, it can reach the object of healing within a short period of time, makes to greatly reduce pathologic scar more afterwards.
Detailed description of the invention
Below the present invention is described in further detail:
embodiment one
After getting Rhizoma Coptidis 120 parts, Cortex Phellodendri 120 parts, the Radix Astragali 120 parts, Radix Sanguisorbae 120 parts, Radix Rumicis 100 parts, Rhizoma Polygoni Cuspidati 100 parts, Radix Arnebiae (Radix Lithospermi) 80 parts, cleaning up respectively, be ground into 100 object fine powders to join in 10000 parts of pure sesame oils and soak after 48 hours, again the medicine of immersion and pure sesame oil big fire are boiled to boiling, slow fire boiling is used instead again, until fluid is rendered as golden yellow can stop decoction, elimination medicinal residues after boiling; To be cooledly pour into equably to decoct in well-done medicine oil after mixing to when 80 degree by the Olibanum 50 parts crushed, Myrrha 50 parts, Borneolum Syntheticum 50 parts, 654-2 being 20 parts, add the denseness that liquid paraffin regulating ointment is applicable to applying again, obtain this patent medicine ointment, after waiting cooling, sterile filling is stand-by.
The present invention's pharmaceutical properties used and pharmacological action are respectively:
Rhizoma Coptidis: property bitter cold, heat clearing and damp drying, eliminating fire and detoxication.Property bitter cold, heat clearing and damp drying, eliminating fire and detoxication.
Cortex Phellodendri: property bitter cold, heat clearing and damp drying, nourishing YIN to lower pathogenic fire, removing toxic substances convergence.
The Radix Astragali: sweet in the mouth slightly warm in nature, benefiting QI for strengthening the superficies, arresting sweating take off admittedly, hold in the palm effect of skin ulcer granulation promoting, open sore part disunion of a specified duration.
Radix Sanguisorbae: cold in nature, has Qinghuo Jiedu effect, cooling blood and relieving pain, sore, carbuncle and painful swelling, burn due to hot liquid or fire.
Radix Rumicis: heat-clearing and toxic substances removing; Cooling blood for hemostasis; Removing blood stasis to reduce swelling; Carbuncle pyogenic infections from tumour or sore; Scald; Scabies; Eczema etc.
Rhizoma Polygoni Cuspidati: the effect with heat-clearing and toxic substances removing, dampness removing, promoting blood circulation and stopping pain, Rhizoma Polygoni Cuspidati ingredient emodin and polygonin have strong inhibition effect to staphylococcus aureus, bacillus pyocyaneus.
Radix Arnebiae (Radix Lithospermi): removing heat from blood, invigorates blood circulation, removing toxic substances rash.Contain for heat in blood poison, macule purple is black, skin infection, eczema, burn due to hot liquid or fire.
Olibanum: regulating qi and activating blood, analgesic therapy, chase after poison effect, control carbuncle pyogenic infections from tumour or sore, traumatic injury.
Myrrha: property hardship is flat, promoting blood circulation and stopping pain, expelling pus and promoting granulation.
Borneolum Syntheticum: property is worked hard, clearing heat for detumescence, antipruritic pain relieving.
654-2: remove affected part arteriolospasm, expansion thin vessels, increases local blood supply, improves local microcirculation, strengthens histiocyte metabolism and repair function.
Pure sesame oil: have removing toxic substances and promoting granulation effect.
Liquid paraffin: can mix with most fatty oil or volatile oil, the denseness of regulating drug ointment.
Above-mentioned all medicine compatibilities are superior, and reasonable recipe is played removing toxic substances and promoting subsidence of swelling, heat clearing away expelling pathogenic factors from the exterior, removing the necrotic tissue and promoting granulation altogether, the effects such as diminishing inflammation and resolving masses, facilitated slough and come off, cambium ramp, for patients with bedsore alleviates misery.This medicine ointment prescription system pure Chinese medicinal preparation, determined curative effect, safe and reliable, without any side effects, medicine source is extensively abundant, and price is lower, and production technology is simple, easily operates.Bedsore wound is changed dressings, once a day, preparation technology is simple, with low cost, easy to use and safety, be convenient to town and country extensive use.
Using method: by bedsore wound 0.1% rivanol irrigation and disinfection, then clean wound surface with normal saline, if wound surface has slough according to circumstances suitably to be removed.Wound surface residual moisture is gently blotted with antiseptic gauze after debridement, then medicine ointment being fallen a little Sterilizing bowl and appropriate antiseptic gauze stirs evenly rear covering two layers (every square centimeter of wound surface is about 2g medicine ointment) on wound surface, external sterilizing gauze 5-6 layer wraps up, bandage fixing again, change dressings every day once to recovery from illness.
application examples one
Choose patients with bedsore 66 example, through comprehensive health check-up, all without complication such as septicemia.Wherein man 38 example, female 28 example, age 22-75 year.All cases is divided into treatment group and matched group at random, and often organize 33 examples, two groups of cases are in sex, and at the age, the state of an illness, the aspect no significant difference such as the course of disease (p > 0.05), have comparability.
Therapeutic Method:
1, treatment group: use normal saline to be cleaned by bedsore wound, decubital ulcer medicine ointment mixing of the present invention being disinfected after gauze stirs is covered on wound surface, every square centimeter of wound surface is about 2g medicine ointment (by using method operation), and changing dressings every day once, seven days is a course for the treatment of.
2, matched group: use normal saline to be cleaned by bedsore wound, be coated with Gentian Violet liquid medicine in affected part, area, slightly larger than affected part, is changed dressings once every day, seven days is a course for the treatment of.
Curative effect determinate standard:
People's Republic of China's traditional Chinese medicine industry standard " surgery of Chinese medicine Illnesses Diagnoses criterion of therapeutical effect " that reference State Administration of Traditional Chinese Medicine issues, Ministry of Public Health " new Chinese medicine clinical research guide " formulate curative effect grade scale.
Recovery from illness: ulcer surface heals completely, clinical symptom disappearance, follows up a case by regular visits to 3 months without recurrence.Effective: ulcer area reduces and reaches more than 70%, and clinical symptoms disappears substantially.Take a turn for the better: ulcer area reduces more than 30%, clinical symptoms is improved.Invalid: treat 3 courses for the treatment of, ulcer area is unchanged, or less than 30%, or expand, clinical symptoms is without improvement.
Efficacy result:
Treatment group 33 example, cures 27 examples, effective 3 examples, effective 2 examples, invalid 1 example, and cure rate is 97%, matched group 33 example, cures 16 examples, effective 4 examples, effective 5 examples, and invalid 8 examples, cure rate is 76%.Treatment group cure rate is apparently higher than matched group (two groups of results compare P < 0.01, and difference has statistical significance).Detailed results is in table 1.
Result shows, decubital ulcer medicine ointment of the present invention is greatly improved than traditional remedies in curative effect, has good therapeutic effect clinically; Matched group has 8 routine patients and occurs side effect, and uses the patient of ointment of the present invention, only has 1 routine patient to occur untoward reaction, illustrates that ointment toxic and side effects of the present invention is little.
Model case:
Lee, female, 56 years old, because there is hemiplegia in patient, need be unable to leave the bed, back, waist all occurs decubital ulcer, and Western medicine of repeatedly seeking medical advice is invalid, uses medicine ointment of the present invention external application one week, and stopping of festering, redness starts to disappear throughout the year.Continue external application after two weeks, closing up and heal in affected part, gets well.
Chen, man, 47 years old, patient causes high paraplegia because of traffic accident, decubital ulcer in bed future trouble half a year, after existing method treatment, still have the wound of 5-6cm size cannot heal at rumpbone place always, degree of depth 1-2cm, visible rumpbone, the external application of rear employing medicine ointment of the present invention is after one week, and ulcer depths grows new granulation, pain is alleviated to some extent, continue the drug of topical application after three weeks, closing up and heal in affected part, follows up a case by regular visits to without recurrence.
Hu, man, 69 years old, because of paraplegia after wound 3 months, RG had the II ° of decubital ulcer face of one 5 × 6 centimetres, decubital ulcer had yellow black to form a scab layer.AD: 1, paraplegia 2, decubital ulcer after wound.Treatment is passed through: improve every inspection after being admitted to hospital, and local gives debridement except crust, and use medicine ointment of the present invention external application after one week after debridement, ulcer depths grows granulation, and pain is alleviated to some extent, and patient mental also take a favorable turn, and changes dressings every day once, and within three weeks, rear decubital ulcer is fully recovered and left hospital.
Liu, female, 70 years old, because of cerebral infarction paraplegia 2 months, household was ignorant of nursing knowledge, dare not move patient, and in the bed January of being in, whole body rear pillow part, scapula, sacrococcygeal region many places there occurs decubital ulcer.Human health screening T:37.6 DEG C P:72 beat/min R:17 beat/min BP:150/70mmHg, cardiopulmonary (-), rear pillow part has the bulla of 6 × 4 centimetres, the II ° of decubital ulcer that scapula is 6 × 5 centimetres, sacrum tail 7 × 5 centimetres of III ° of decubital ulcers.Except occipitalia, all there is inflammatory exudate, to antibiotic infection control, reduce local compression, increase and stand up number of times.Under sterile working, wipe out slough and blister to whole body decubital ulcer, with using medicine ointment of the present invention external application after one week after normal saline debridement, ulcer depths grows granulation, and pain is alleviated to some extent, and after January, decubital ulcer healing, is discharged from hospitals upon recovery.
Claims (2)
1. treat a decubital ulcer medicine ointment prescription, it is characterized in that: described prescription is counted by weight: Rhizoma Coptidis 120 parts, Cortex Phellodendri 100 parts, the Radix Astragali 120 parts, Radix Sanguisorbae 120 parts, Radix Rumicis 100 parts, Rhizoma Polygoni Cuspidati 100 parts, Radix Arnebiae (Radix Lithospermi) 80 parts, Olibanum 50 parts, Myrrha 50 parts, Borneolum Syntheticum 50 parts, 654-2 are 20 parts, Oleum sesami 10000 parts, liquid paraffin consistency modifiers.
2. treat the preparation method of decubital ulcer medicine ointment prescription for one kind: it is characterized in that: described method for by Rhizoma Coptidis 120 parts, Cortex Phellodendri 120 parts, the Radix Astragali 120 parts, Radix Sanguisorbae 120 parts, Radix Rumicis 100 parts, Rhizoma Polygoni Cuspidati 100 parts, Radix Arnebiae (Radix Lithospermi) 80 parts, clean up respectively after, be ground into 100 object fine powders to join in 10000 parts of pure sesame oils and soak after 48 hours, again the medicine of immersion and pure sesame oil big fire are boiled to boiling, slow fire boiling is used instead again, until fluid is rendered as golden yellow can stop decoction, elimination medicinal residues after boiling; To be cooledly pour into equably decoct in well-done medicine oil after mixing to when 80 degree by the Olibanum 50 parts crushed, Myrrha 50 parts, Borneolum Syntheticum 50 parts, 654-2 being 20 parts, then add the denseness that liquid paraffin regulating ointment is applicable to applying, obtain medicine ointment.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111588778A (en) * | 2020-07-07 | 2020-08-28 | 仝玉霞 | A Chinese medicinal ointment for treating burn, scald and bedsore, and its preparation method |
| CN115381883A (en) * | 2022-09-27 | 2022-11-25 | 罗俊 | Wuhuang burn sore paste and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101879283A (en) * | 2010-06-13 | 2010-11-10 | 中国人民解放军第三军医大学 | Novel membrane spraying preparation for skin trauma and preparation method |
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| CN115381883A (en) * | 2022-09-27 | 2022-11-25 | 罗俊 | Wuhuang burn sore paste and preparation method thereof |
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Application publication date: 20160302 |