CN109674945A - The Chinese medicine composition and preparation method thereof of ulcer is cured in a kind of myogenic hemostasia and detumescence analgesic - Google Patents

The Chinese medicine composition and preparation method thereof of ulcer is cured in a kind of myogenic hemostasia and detumescence analgesic Download PDF

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CN109674945A
CN109674945A CN201910164989.2A CN201910164989A CN109674945A CN 109674945 A CN109674945 A CN 109674945A CN 201910164989 A CN201910164989 A CN 201910164989A CN 109674945 A CN109674945 A CN 109674945A
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chinese medicine
ulcer
medicine composition
radix
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范艺缤
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Nanchong Traditional Chinese Medicine Hospital
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Nanchong Traditional Chinese Medicine Hospital
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Abstract

The present invention provides the Chinese medicine compositions that ulcer is cured in a kind of analgesic of myogenic hemostasia and detumescence, it is prepared by the bulk pharmaceutical chemicals of following weight proportion: 80~360 parts of the bletilla striata, 80~360 parts of olibanum, 80~360 parts of myrrh, 80~360 parts of catechu, 80~360 parts of Chinese gall, 80~360 parts of the coptis, 80~360 parts of kuh-seng, 80~360 parts of Cortex Phellodendri, 40~180 parts of dragon's blood, 40~180 parts of Pollen Typhae, 40~180 parts of Radix Notoginseng, 40~180 parts of the root of Dahurain angelica, 40~180 parts of Asian puccoon, raw 40~180 parts of Radix Astragali, 20~60 parts of Radix Angelicae Sinensis, 20~60 parts of borneol, 20~60 parts of Radix Glycyrrhizae.The present invention also provides the preparation methods of the Chinese medicine composition.Chinese medicine composition energy myogenic hemostasis provided by the invention, swelling and pain relieving, more ulcer, have exact curative effect especially for ulcer wound surfaces such as bedsores, and easy to use, have stronger practical application value.

Description

The Chinese medicine composition and preparation method thereof of ulcer is cured in a kind of myogenic hemostasia and detumescence analgesic
Technical field
The present invention relates to the field of Chinese medicines, and in particular to the Chinese medicine composition and its system of ulcer are cured in a kind of myogenic hemostasia and detumescence analgesic Preparation Method.
Background technique
People are injured unavoidable in carrying out production and living, and the surface of a wound is difficult to heal clinical also more more when operative treatment See.Meanwhile wound, microorganism infection, tumour, dyshaemia and neurological dysfunction, immunologic dysfunction or congenital skin lack Damage etc. also easily causes limitation Skin preparation, forms ulcer.The long disunion of the surface of a wound, seriously affects quality of life.Wherein, Pressure ulcer (referred to as pressure sore, also known as bedsore) is that continuous ischemia, anoxic, nutrition occurs since local organization is pressurized for a long time It is bad and cause tissue fester downright bad.The problem of pressure ulcer is a universality in rehabilitation, nursing.According to related document report Road, there are about 60,000 people to die of pressure sore concomitant symptoms every year.It is with a long history but existing that ulcer aspect is cured in the analgesic of traditional Chinese medicine myogenic hemostasia and detumescence There is not yet being cured the relevant report of the Chinese medicine composition of ulcer about myogenic hemostasia and detumescence of the present invention analgesic in technology.
Summary of the invention
The purpose of the present invention is to provide the Chinese medicine compositions and preparation method thereof that ulcer is cured in a kind of analgesic of myogenic hemostasia and detumescence.
The present invention provides the Chinese medicine compositions that ulcer is cured in a kind of analgesic of myogenic hemostasia and detumescence, it is by following weight proportion Bulk pharmaceutical chemicals are prepared: 80~360 parts of the bletilla striata, 80~360 parts of olibanum, and 80~360 parts of myrrh, 80~360 parts of catechu, Chinese gall 80~360 parts, 80~360 parts of the coptis, 80~360 parts of kuh-seng, 80~360 parts of Cortex Phellodendri, 40~180 parts of dragon's blood, Pollen Typhae 40~ 180 parts, 40~180 parts of Radix Notoginseng, 40~180 parts of the root of Dahurain angelica, 40~180 parts of Asian puccoon, raw 40~180 parts of Radix Astragali, 20~60 parts of Radix Angelicae Sinensis, 20~60 parts of borneol, 20~60 parts of Radix Glycyrrhizae.
Further, aforementioned Chinese medicine composition is prepared by the bulk pharmaceutical chemicals of following weight proportion: 300 parts of the bletilla striata, cream It is 300 parts fragrant, 300 parts of myrrh, 300 parts of catechu, 300 parts of Chinese gall, 300 parts of the coptis, 300 parts of kuh-seng, 300 parts of Cortex Phellodendri, dragon's blood 150 Part, 150 parts of Pollen Typhae, 150 parts of Radix Notoginseng, 150 parts of the root of Dahurain angelica, 150 parts of Asian puccoon, raw 150 parts of Radix Astragali is 50 parts of Radix Angelicae Sinensis, 50 parts of borneol, sweet 50 parts of grass.
Further, aforementioned Chinese medicine composition is that by the medicinal powder of bulk pharmaceutical chemicals of the weight proportion, the water of bulk pharmaceutical chemicals or have Solvent extract is active constituent, in addition the preparation that pharmaceutically acceptable auxiliary material is prepared.
Further, the preparation is external preparation.
Further, the external preparation is lotion, plastics, liniment, paste, decoction, powder, ointment, aerosol Or spray.
The present invention also provides a kind of methods for preparing Chinese medicine composition above-mentioned, it includes the following steps:
A, the raw material of each weight proportion is weighed;
B, raw material directly beaten to powder, or after adding water or organic solvent to extract, pharmaceutically acceptable auxiliary material or auxiliary is added Property ingredient is prepared.
The present invention also provides Chinese medicine compositions above-mentioned in preparation myogenic hemostasis, swelling and pain relieving, is cured in the drug of ulcer Purposes.
Further, the drug is the drug of wound healing.
Further, the surface of a wound is ulcer wound surface.
Further, the ulcer wound surface is bedsore.
Myogenic hemostasia and detumescence of the present invention analgesic be cured ulcer Chinese medicine composition be by the bletilla striata, olibanum, myrrh, catechu, Chinese gall, The coptis, kuh-seng, Cortex Phellodendri, dragon's blood, Pollen Typhae, Radix Notoginseng, the root of Dahurain angelica, Asian puccoon, raw Radix Astragali, Radix Angelicae Sinensis, borneol and Radix Glycyrrhizae composition.
Pollen Typhae is the dry pollen of Typhaceae plant typha orientalis, the turbid cattail of water or congener.
Raw Radix Astragali is that the root of astragalus mongholicus or astragalus membranaceus of leguminous plant shines dry chip and obtains.
Bletilla striata astringing to arrest bleeding, detumescence and promoting granulation in side, olibanum, myrrh detumescence and promoting granulation, removing blood stasis and acesodyne, catechu hygroscopic myogenic are held back Sore, the coptis, kuh-seng, Cortex Phellodendri, the root of Dahurain angelica, Chinese gall, Asian puccoon removing toxic substances sore, dragon's blood removing blood stasis and relieving pain, hemostasia and promoting granulation, Pollen Typhae, Radix Notoginseng Dissipating stasis and stanching bleeding, detumescence ding-tong, raw Radix Astragali, Radix Angelicae Sinensis QI invigorating and blood, borneol clearing away heat to and alleviating pain, Radix Glycyrrhizae detoxification sore treatment, coordinating the drug actions of a prescription.All medicines It shares, plays myogenic hemostasis altogether, swelling and pain relieving, is cured the benefits of ulcer.
Chinese medicine composition energy myogenic hemostasis provided by the invention, swelling and pain relieving, more ulcer, are created especially for ulcer such as bedsores There is exact curative effect in face, and easy to use, has stronger practical application value.
Obviously, above content according to the present invention, according to the ordinary technical knowledge and customary means of relevant art, Under the premise of not departing from above-mentioned basic fundamental thought of the invention, the modification, replacement or change of other diversified forms can also be made.
The specific embodiment of form by the following examples remakes further specifically above content of the invention It is bright.But the range that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to example below.It is all to be based on above content of the present invention The technology realized all belongs to the scope of the present invention.
Specific embodiment
The preparation of 1 the traditional chinese medicine composition of the invention of embodiment
(1) raw material: bletilla striata 300g, olibanum 300g, myrrh 300g, catechu 300g, Chinese gall 300g, coptis 300g, kuh-seng 300g, Cortex Phellodendri 300g, dragon's blood 150g, Pollen Typhae 150g, Radix Notoginseng 150g, root of Dahurain angelica 150g, Asian puccoon 150g, raw Radix Astragali 150g, Radix Angelicae Sinensis 50g, borneol 50g, Radix Glycyrrhizae 50g.
(2) preparation method: weighing bulk pharmaceutical chemicals by above-mentioned weight proportion, and bulk pharmaceutical chemicals are broken into thick end, is impregnated with rape oil 5kg thick End one week, is subsequently placed on fire and is heated to oily rolling, then small fire is decocted slowly to dregs of a decoction zoom Huang Weidu, after medical fluid cooling, filtering Remove slag, bottling to get.
The preparation of 2 the traditional chinese medicine composition of the invention of embodiment
(1) raw material: bletilla striata 200g, olibanum 200g, myrrh 200g, catechu 200g, Chinese gall 200g, coptis 200g, kuh-seng 200g, Cortex Phellodendri 200g, dragon's blood 100g, Pollen Typhae 100g, Radix Notoginseng 100g, root of Dahurain angelica 100g, Asian puccoon 100g, raw Radix Astragali 100g, Radix Angelicae Sinensis 30g, borneol 30g, Radix Glycyrrhizae 30g.
(2) preparation method: weighing bulk pharmaceutical chemicals by above-mentioned weight proportion, and bulk pharmaceutical chemicals are broken into thick end, is impregnated with rape oil 4kg thick End one week, is subsequently placed on fire and is heated to oily rolling, then small fire is decocted slowly to dregs of a decoction zoom Huang Weidu, after medical fluid cooling, filtering Remove slag, bottling to get.
The preparation of 3 the traditional chinese medicine composition of the invention of embodiment
(1) raw material: bletilla striata 100g, olibanum 100g, myrrh 100g, catechu 100g, Chinese gall 100g, coptis 100g, kuh-seng 100g, Cortex Phellodendri 100g, dragon's blood 50g, Pollen Typhae 50g, Radix Notoginseng 50g, root of Dahurain angelica 50g, Asian puccoon 50g, raw Radix Astragali 50g, Radix Angelicae Sinensis 25g, ice Piece 25g, Radix Glycyrrhizae 25g.
(2) preparation method: weighing bulk pharmaceutical chemicals by above-mentioned weight proportion, and bulk pharmaceutical chemicals are broken into thick end, is impregnated with rape oil 3kg thick End one week, is subsequently placed on fire and is heated to oily rolling, then small fire is decocted slowly to dregs of a decoction zoom Huang Weidu, after medical fluid cooling, filtering Remove slag, bottling to get.
Beneficial effects of the present invention are proved below by way of specific clinical test.
The clinical efficacy of 1 the traditional chinese medicine composition of the invention of test example
1, clinical data
Choose the third phase pressure sore i.e. bedsore of either shallow ulcerative stage being hospitalized during in January, 2017~2018 year December in the court Patient 44, control group and test group are divided into using random packet mode.Wherein control group 22, male 15, female 7, the age 52~90 years old, average (66.7 ± 3.5) year.Test group 22, male 13, female 9, the age 50~92 years old, average (65.24 ± 7.5) year.
1.1 patients are included in standard
Meet the diagnosis mark of bedsore in People's Republic of China's traditional Chinese medicine industry standard Standards for Diagnosis and Curative Effect of Chinese Medical Symptom Standard, vital sign is steady, patient's informed consent, the person that is ready partner treatment.
1.2 patient's exclusion criterias
Patient and family members refuse partner treatment person;Allergic constitution is known to this medicine ingredient allergy sufferers;Participating in other The patient of clinical drug trial.
2, therapeutic scheme
2.1 therapeutic agent
Experimental group: the Chinese medicine composition of the preparation of the embodiment of the present invention 1 is given.
Control group: Kangfuxin Liquid is given.
2.2 specific medications are as follows:
While Cure the Primary Disease, Local treatment is given as early as possible.Two groups are all given 0.5% povidone before the treatment Iodine solution wipes the surface of a wound, is rinsed later with 0.9% sodium chloride injection, removes necrotic tissue.Control group Kangfuxin Liquid soak, Daily dressing 2 times, keep the surface of a wound wet, until wound healing.Experimental group gives the Chinese medicine composition of the preparation of the embodiment of the present invention 1 Soak, daily dressing 2 times keep the surface of a wound wet, until wound healing.It is treated after 2 weeks according to the wound healing degree of patient Effect evaluation.
3, observation of curative effect
3.1 criterions of therapeutical effect: " the disease of tcm Standardization of diagnosis and curative effect " promulgated referring to State Administration of Traditional Chinese Medicine determines.
It cures: decubitus ulcer healing;
Improve: decubitus ulcer area is obviously reduced;
Invalid: decubitus ulcer face is without improvement.
3.2 treatment results
It is as shown in table 1:
The treatment results of 1 the traditional chinese medicine composition of the invention of table
Group It cures It is effective In vain It is efficient
Experimental group (22 people) 18 4 0 100%
Control group (22 people) 8 11 3 86.36%
Experiment conclusion: the traditional chinese medicine composition of the invention for the ulcer wound surfaces such as bedsore, can be effectively controlled infection, swelling and pain relieving, Wound healing, it is curative for effect, it is easy to use, it is worth clinical application.
To sum up, Chinese medicine composition energy myogenic hemostasis provided by the invention, swelling and pain relieving, more ulcer, especially for bedsore etc. Ulcer wound surface has exact curative effect, and easy to use, has stronger practical application value.

Claims (10)

1. the Chinese medicine composition that ulcer is cured in a kind of myogenic hemostasia and detumescence analgesic, it is characterised in that: it is by the original of following weight proportion Material medicine is prepared: 80~360 parts of the bletilla striata, 80~360 parts of olibanum, and 80~360 parts of myrrh, 80~360 parts of catechu, Chinese gall 80 ~360 parts, 80~360 parts of the coptis, 80~360 parts of kuh-seng, 80~360 parts of Cortex Phellodendri, 40~180 parts of dragon's blood, Pollen Typhae 40~180 Part, 40~180 parts of Radix Notoginseng, 40~180 parts of the root of Dahurain angelica, 40~180 parts of Asian puccoon, raw 40~180 parts of Radix Astragali, 20~60 parts of Radix Angelicae Sinensis, ice 20~60 parts of piece, 20~60 parts of Radix Glycyrrhizae.
2. Chinese medicine composition according to claim 1, it is characterised in that: it is prepared by the bulk pharmaceutical chemicals of following weight proportion It forms: 300 parts of the bletilla striata, 300 parts of olibanum, 300 parts of myrrh, 300 parts of catechu, 300 parts of Chinese gall, 300 parts of the coptis, 300 parts of kuh-seng, 300 parts of Cortex Phellodendri, 150 parts of dragon's blood, 150 parts of Pollen Typhae, 150 parts of Radix Notoginseng, 150 parts of the root of Dahurain angelica, 150 parts of Asian puccoon, raw 150 parts of Radix Astragali, when Return 50 parts, 50 parts of borneol, 50 parts of Radix Glycyrrhizae.
3. Chinese medicine composition according to claim 1 or 2, it is characterised in that: it is by the bulk pharmaceutical chemicals of the weight proportion Medicinal powder, bulk pharmaceutical chemicals water or extractive with organic solvent be active constituent, in addition what pharmaceutically acceptable auxiliary material was prepared Preparation.
4. Chinese medicine composition according to claim 3, it is characterised in that: the preparation is external preparation.
5. Chinese medicine composition according to claim 4, it is characterised in that: the external preparation is lotion, plastics, puts on the skin Agent, paste, decoction, powder, ointment, aerosol or spray.
6. a kind of method for preparing the described in any item Chinese medicine compositions of Claims 1 to 5, it is characterised in that: it includes as follows Step:
A, the raw material of each weight proportion is weighed;
B, raw material directly beaten to powder, or after adding water or organic solvent to extract, be added pharmaceutically acceptable auxiliary material or it is complementary at Divide and is prepared.
7. the described in any item Chinese medicine compositions of Claims 1 to 5 are preparing myogenic hemostasis, swelling and pain relieving, are being cured in the drug of ulcer Purposes.
8. purposes according to claim 7, it is characterised in that: the drug is the drug of wound healing.
9. purposes according to claim 8, it is characterised in that: the surface of a wound is ulcer wound surface.
10. purposes according to claim 9, it is characterised in that: the ulcer wound surface is bedsore.
CN201910164989.2A 2019-03-05 2019-03-05 The Chinese medicine composition and preparation method thereof of ulcer is cured in a kind of myogenic hemostasia and detumescence analgesic Pending CN109674945A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112870295A (en) * 2021-03-22 2021-06-01 丽水市中心医院 Traditional Chinese medicine granulation promoting powder and application thereof
CN113425797A (en) * 2021-07-02 2021-09-24 昆明市第二人民医院 Medicine and dressing for healing skin wound and preparation method thereof

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CN1548139A (en) * 2003-05-19 2004-11-24 魏茂武 Bedsore ointment and its prepn process
CN105535334A (en) * 2016-02-20 2016-05-04 胶州市人民中医医院 Radix arnebiae and milkvetch root granulation-promoting extract and preparation method
CN105535508A (en) * 2016-01-28 2016-05-04 胶州市人民中医医院 Radix astragali and sanguis draxonis bedsore healing unguent and preparation method

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CN105535508A (en) * 2016-01-28 2016-05-04 胶州市人民中医医院 Radix astragali and sanguis draxonis bedsore healing unguent and preparation method
CN105535334A (en) * 2016-02-20 2016-05-04 胶州市人民中医医院 Radix arnebiae and milkvetch root granulation-promoting extract and preparation method

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112870295A (en) * 2021-03-22 2021-06-01 丽水市中心医院 Traditional Chinese medicine granulation promoting powder and application thereof
CN113425797A (en) * 2021-07-02 2021-09-24 昆明市第二人民医院 Medicine and dressing for healing skin wound and preparation method thereof

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