CN105663753A - Compound rhizoma coptidis ointment and method for preparing same - Google Patents

Compound rhizoma coptidis ointment and method for preparing same Download PDF

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Publication number
CN105663753A
CN105663753A CN201610178204.3A CN201610178204A CN105663753A CN 105663753 A CN105663753 A CN 105663753A CN 201610178204 A CN201610178204 A CN 201610178204A CN 105663753 A CN105663753 A CN 105663753A
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radix
ointment
rhizoma
rhizoma coptidis
compound
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缪东初
毛翠兰
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones

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Abstract

The invention discloses compound rhizoma coptidis ointment and a method for preparing the same. The compound rhizoma coptidis ointment comprises 15 g of rhizoma coptidis, 15 g of radix angelicae sinensis, 15 g of rhizoma bletillae, 9 g of radix et rhizoma rhei, 9 g of rhizoma corydalis, 9 g of radix angelicae dahuricae, 12 g of pericarpium citri reticulatae, 9 g of radix paeoniae alba, 20 g of radix astragali, 15 g of radix rehmanniae, 500 g of oleum sesami and 50 g of yellow wax. The compound rhizoma coptidis ointment and the method have the advantages that curative effects of clearing heat, removing toxicity, stopping bleeding, diminishing swelling and regenerating tissues to heal sore can be realized by the compound rhizoma coptidis ointment, the compound rhizoma coptidis ointment is high in healing speed, free of side effects and applicable to scald, pressure sore, skin infection, ulcer, unhealed postoperative wound and the like, and scars can be prevented; the compound rhizoma coptidis ointment which can be medicinal oil is in an oral dosage form and can be applied to treating upper digestive tract ulcer; the compound rhizoma coptidis ointment which can be paste is in an external application dosage form and can be applied to wound healing treatment.

Description

Compound coptis chinensis ointment and preparation method thereof
Technical field
The present invention relates to field of medicaments, be specifically related to a kind of compound coptis chinensis ointment and preparation method thereof.
Background technology
Burn and scald, pressure ulcer, diabetic foot merge the wound healings such as skin ulcer, operative incision disunion, ulcerative colitis, are always up surgery urgent need to solve the problem. Therefore applicant through 20 years clinical empirical summary and thousands of example clinical case, ancient prescription is arranged, developing can a kind of compound coptis chinensis ointment.
Summary of the invention
Having it is an object of the invention to provide a kind of compound coptis chinensis ointment and preparation method thereof, through the clinical observation of clinical thousands of examples, had heat-clearing and toxic substances removing, hemostasia and detumescence, the curative effect of promoting tissue regeneration and ulcer healing, healing is fast, without cicatrix, has no side effect, evident in efficacy.
For achieving the above object, the technical scheme that the present invention takes is:
Compound coptis chinensis ointment, is prepared from by following raw material:
Rhizoma Coptidis 15g, Radix Angelicae Sinensis 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Radix Et Rhizoma Rhei 9g, Rhizoma Corydalis 9g, Radix Angelicae Dahuricae 9g, Pericarpium Citri Reticulatae 12g, Radix Paeoniae Alba 9g, Radix Astragali 20g, Radix Rehmanniae 15g. 500 grams of Oleum Sesami, 50 grams of Cera Flava.
The preparation method of above-mentioned compound coptis chinensis ointment, comprises the steps:
S1, weigh Rhizoma Coptidis, Radix Angelicae Sinensis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Pericarpium Citri Reticulatae, the Radix Paeoniae Alba, the Radix Astragali, the Radix Rehmanniae, Oleum Sesami and Cera Flava by the formula described in claim 1;
S2, the Rhizoma Coptidis weighed, Radix Angelicae Sinensis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Pericarpium Citri Reticulatae, the Radix Paeoniae Alba, the Radix Astragali, the Radix Rehmanniae are soaked 3 days with the Oleum Sesami that weighs after, withered to medicine with slow fire infusion, filtering of removing slag, obtain oil preparation;
S3, gained oil preparation is heated after add the Cera Flava that weighs of step S1, slow fire receives cream slowly, obtains unguentum.
The present invention has heat-clearing and toxic substances removing, hemostasia and detumescence, the curative effect of promoting tissue regeneration and ulcer healing, and healing is fast, without cicatrix, has no side effect, it is adaptable to scald, pressure ulcer, skin infection, ulcer, postoperative wound surface disunion etc., oil preparation is peroral dosage form, can be used for treating ulcer of upper digestive tract. Unguentum is exterior-applied formulation, can be used for wound healing treatment.
Detailed description of the invention
In order to make objects and advantages of the present invention clearly understand, below in conjunction with embodiment, the present invention is further elaborated. Should be appreciated that specific embodiment described herein is only in order to explain the present invention, is not intended to limit the present invention.
Embodiments provide a kind of compound coptis chinensis ointment, following raw material be prepared from:
Rhizoma Coptidis 15g, Radix Angelicae Sinensis 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Radix Et Rhizoma Rhei 9g, Rhizoma Corydalis 9g, Radix Angelicae Dahuricae 9g, Pericarpium Citri Reticulatae 12g, Radix Paeoniae Alba 9g, Radix Astragali 20g, Radix Rehmanniae 15g.500 grams of Oleum Sesami, 50 grams of Cera Flava.
The preparation method that the embodiment of the present invention additionally provides above-mentioned compound coptis chinensis ointment, comprises the steps:
S1, weigh Rhizoma Coptidis, Radix Angelicae Sinensis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Pericarpium Citri Reticulatae, the Radix Paeoniae Alba, the Radix Astragali, the Radix Rehmanniae, Oleum Sesami and Cera Flava by the formula described in claim 1;
S2, the Rhizoma Coptidis weighed, Radix Angelicae Sinensis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Pericarpium Citri Reticulatae, the Radix Paeoniae Alba, the Radix Astragali, the Radix Rehmanniae are soaked 3 days with the Oleum Sesami that weighs after, withered to medicine with slow fire infusion, filtering of removing slag, obtain oil preparation;
S3, gained oil preparation is heated after add the Cera Flava that weighs of step S1, slow fire receives cream slowly, obtains unguentum.
Embodiment 1
Cold injury------patient, an xx, man, 57 years old. Because of both hands cold injury 2 days. This trouble is previously mentally ill medical history. Before 2 days, running away from home voluntarily 6 hours, both hands cold injury occur, conscious numbness, without pain. Go to a doctor to multiple hospitals, it is proposed that operation amputation. For seeking expectant treatment, therefore go to a doctor in December in 2015 my institute's surgery of Chinese medicine medical on the 1st. Looking into: both hands end skin mulberry, there is vesicle on surface, without touching a tender spot, with acupuncture without hemorrhage, insensitive. Diagnosis: cold injury. Give to be coated with outside compound coptis chinensis ointment. Coordinate oral Chinese medicine. After 25 days, Epidermal necrosis comes off, the new skin reparation of substrate, and only right hand forefinger, middle finger and left hand little finger of toe finger tip are shown in that 1.0cmx1.0cm, 1.0cmx0.8cm, 0.8cmx0.5cm muscular death is formed a scab respectively. continue externally coated compound Rhizoma Coptidis ointment. Fully recover after 35 days, without any cicatrix.
Embodiment 2
Scald patient, Lee x, man, 45 years old. Scald 2 hours because boiling water causes right upper extremity. Go to a doctor on May 20th, 2014. Before 2 hours, because of end chaffy dish, boiling water is toppled over and is caused right upper extremity and scald, and looks into right upper extremity 8% areas of skin exfoliation, it is seen that forearm basilar part skin whitens, palm oar side skin skin blister come off after substrate oozing of blood, be around dispersed in the blister that differs in size. Diagnosis: scald [I degree, shallow II degree, deep II degree] and give local topical compound coptis chinensis ointment. Coordinate antiinflammatory symptomatic treatment simultaneously. Fully recover after 25 days. Without cicatrix.
Embodiment 3
Patients with bedsore, an xx, women, 82 years old. Because " cerebral thrombosis sequela, cerebellar atrophy " lies in bed 3 years. Before 2 months, tail sacrum portion, buttocks many places ulcer occur, be successively in hospital 2 times, give antiinflammatory, improve the medicines such as local circulation, coordinate the treatments such as external nitrofural, Petroleum gauze, chlormycetin powder, have no improvement, and increase the weight of gradually. Therefore carry out surgery of Chinese medicine and go to a doctor. Look into: become thin, nutrition relatively, slurred speech, bradykinesia, the visible about 10.0cmx10.0cm in tail sacrum portion, bilateral buttocks is visible each 5.0cmx5.0cm pitting wound surface respectively, and deep 3cm has a little canescence secretions, matter is rare, frowziness, and its basilar part is deep to fascia tissue, and portion of tissue is downright bad. Tcm diagnosis: decubital ulcer [deficiency of qi and blood is held under the arm damp and hot]. Treatment: 1, remove slough under local anaesthesia, with hydrogen peroxide and normal saline washing wound surface, remove degree with hemorrhage, expose flesh tissue for degree, the sliver that externally used compound Rhizoma Coptidis ointment soaks. 2, oral Ginseng Bolus for tonifying spleen and ZHIBAI DIHUANG WAN are coordinated. 3, nutrition is noted, it is to avoid local compression. Recovery from illness in 118 days.
Embodiment 4
Perianal postoperative wound surface-patient, male, 28 years old. Because the disposable incision Multiple insion of perianal abscess row internal orifice hangs flotation line drainage. The sliver that postoperative compound coptis chinensis ointment soaks is changed dressings.Recovery from illness in 24 days. Without any cicatrix.
The above is only the preferred embodiment of the present invention; it should be pointed out that, for those skilled in the art, under the premise without departing from the principles of the invention; can also making some improvements and modifications, these improvements and modifications also should be regarded as protection scope of the present invention.

Claims (2)

1. compound coptis chinensis ointment, it is characterised in that be prepared from by following raw material:
Rhizoma Coptidis 15g, Radix Angelicae Sinensis 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Radix Et Rhizoma Rhei 9g, Rhizoma Corydalis 9g, Radix Angelicae Dahuricae 9g, Pericarpium Citri Reticulatae 12g, Radix Paeoniae Alba 9g, Radix Astragali 20g, Radix Rehmanniae 15g. 500 grams of Oleum Sesami, 50 grams of Cera Flava.
2. the preparation method of compound coptis chinensis ointment as claimed in claim 1, it is characterised in that comprise the steps:
S1, weigh Rhizoma Coptidis, Radix Angelicae Sinensis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Pericarpium Citri Reticulatae, the Radix Paeoniae Alba, the Radix Astragali, the Radix Rehmanniae, Oleum Sesami and Cera Flava by the formula described in claim 1;
S2, the Rhizoma Coptidis weighed, Radix Angelicae Sinensis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Et Rhizoma Rhei, Rhizoma Corydalis, the Radix Angelicae Dahuricae, Pericarpium Citri Reticulatae, the Radix Paeoniae Alba, the Radix Astragali, the Radix Rehmanniae are soaked 3 days with the Oleum Sesami that weighs after, withered to medicine with slow fire infusion, filtering of removing slag, obtain oil preparation;
S3, gained oil preparation is heated after add the Cera Flava that weighs of step S1, slow fire receives cream slowly, obtains unguentum.
CN201610178204.3A 2016-03-21 2016-03-21 Compound rhizoma coptidis ointment and method for preparing same Pending CN105663753A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620275A (en) * 2017-02-28 2017-05-10 缪东初 External ointment and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102258746A (en) * 2011-06-29 2011-11-30 李宏干 Ointment for treating surface of burns and scalds
CN104043039A (en) * 2014-06-03 2014-09-17 舒欣 Rhizoma Coptidis ointment and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102258746A (en) * 2011-06-29 2011-11-30 李宏干 Ointment for treating surface of burns and scalds
CN104043039A (en) * 2014-06-03 2014-09-17 舒欣 Rhizoma Coptidis ointment and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106620275A (en) * 2017-02-28 2017-05-10 缪东初 External ointment and preparation method thereof

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