CN102895600B - Pharmaceutical composition for treatment of varicosity and preparation method thereof - Google Patents
Pharmaceutical composition for treatment of varicosity and preparation method thereof Download PDFInfo
- Publication number
- CN102895600B CN102895600B CN201210423982.6A CN201210423982A CN102895600B CN 102895600 B CN102895600 B CN 102895600B CN 201210423982 A CN201210423982 A CN 201210423982A CN 102895600 B CN102895600 B CN 102895600B
- Authority
- CN
- China
- Prior art keywords
- weight portion
- weight
- radix
- herba
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000011282 treatment Methods 0.000 title claims abstract description 50
- 238000002360 preparation method Methods 0.000 title claims abstract description 34
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 27
- 206010046996 Varicose vein Diseases 0.000 title abstract description 4
- 241000717739 Boswellia sacra Species 0.000 claims abstract description 18
- 241001489978 Eupolyphaga Species 0.000 claims abstract description 18
- 239000004863 Frankincense Substances 0.000 claims abstract description 13
- 239000003814 drug Substances 0.000 claims description 61
- 239000000843 powder Substances 0.000 claims description 28
- 229940079593 drug Drugs 0.000 claims description 27
- 238000000034 method Methods 0.000 claims description 19
- 239000009286 sanguis draxonis Substances 0.000 claims description 18
- 241000756943 Codonopsis Species 0.000 claims description 17
- 241000237903 Hirudo Species 0.000 claims description 17
- 241001057584 Myrrha Species 0.000 claims description 17
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 17
- 241000180649 Panax notoginseng Species 0.000 claims description 17
- 239000000203 mixture Substances 0.000 claims description 11
- 238000000227 grinding Methods 0.000 claims description 6
- 239000002994 raw material Substances 0.000 claims description 6
- 238000002791 soaking Methods 0.000 claims description 6
- 239000002671 adjuvant Substances 0.000 claims description 5
- 238000007654 immersion Methods 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 2
- 229940126680 traditional chinese medicines Drugs 0.000 claims description 2
- 241000736246 Pyrola Species 0.000 abstract description 6
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 244000036905 Benincasa cerifera Species 0.000 abstract 1
- 235000011274 Benincasa cerifera Nutrition 0.000 abstract 1
- 241000981770 Buddleja asiatica Species 0.000 abstract 1
- 244000223760 Cinnamomum zeylanicum Species 0.000 abstract 1
- 241000007126 Codonopsis pilosula Species 0.000 abstract 1
- 240000007311 Commiphora myrrha Species 0.000 abstract 1
- 235000006965 Commiphora myrrha Nutrition 0.000 abstract 1
- 244000124209 Crocus sativus Species 0.000 abstract 1
- 235000015655 Crocus sativus Nutrition 0.000 abstract 1
- 235000014375 Curcuma Nutrition 0.000 abstract 1
- 244000164480 Curcuma aromatica Species 0.000 abstract 1
- 240000009138 Curcuma zedoaria Species 0.000 abstract 1
- 235000003405 Curcuma zedoaria Nutrition 0.000 abstract 1
- 241000545744 Hirudinea Species 0.000 abstract 1
- 241000207925 Leonurus Species 0.000 abstract 1
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 244000028339 Lysimachia nummularia Species 0.000 abstract 1
- 235000016330 Lysimachia nummularia Nutrition 0.000 abstract 1
- 240000001899 Murraya exotica Species 0.000 abstract 1
- 235000008766 Murraya exotica Nutrition 0.000 abstract 1
- 235000009696 Murraya paniculata Nutrition 0.000 abstract 1
- 235000007265 Myrrhis odorata Nutrition 0.000 abstract 1
- 241000123069 Ocyurus chrysurus Species 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 235000003181 Panax pseudoginseng Nutrition 0.000 abstract 1
- 244000290970 Tetrapanax papyrifer Species 0.000 abstract 1
- 244000000728 Teucrium viscidum Species 0.000 abstract 1
- 235000017803 cinnamon Nutrition 0.000 abstract 1
- 239000001812 curcuma zedoaria berg. rosc. Substances 0.000 abstract 1
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 235000019509 white turmeric Nutrition 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 22
- 210000004369 blood Anatomy 0.000 description 21
- 210000004185 liver Anatomy 0.000 description 20
- 208000002193 Pain Diseases 0.000 description 18
- 230000000694 effects Effects 0.000 description 17
- 230000036407 pain Effects 0.000 description 15
- 230000001737 promoting effect Effects 0.000 description 15
- 210000000952 spleen Anatomy 0.000 description 12
- 230000017531 blood circulation Effects 0.000 description 10
- 201000010099 disease Diseases 0.000 description 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 10
- 210000002216 heart Anatomy 0.000 description 10
- 206010047115 Vasculitis Diseases 0.000 description 8
- 235000009508 confectionery Nutrition 0.000 description 8
- 210000003734 kidney Anatomy 0.000 description 8
- 210000003141 lower extremity Anatomy 0.000 description 7
- 210000004072 lung Anatomy 0.000 description 7
- 230000008961 swelling Effects 0.000 description 7
- 208000018262 Peripheral vascular disease Diseases 0.000 description 6
- 238000011084 recovery Methods 0.000 description 6
- 235000011273 Benincasa Nutrition 0.000 description 5
- 241000612166 Lysimachia Species 0.000 description 5
- 241001349593 Praecitrullus Species 0.000 description 5
- 230000008859 change Effects 0.000 description 5
- 238000002347 injection Methods 0.000 description 5
- 239000007924 injection Substances 0.000 description 5
- 231100000614 poison Toxicity 0.000 description 5
- 239000002893 slag Substances 0.000 description 5
- 210000003462 vein Anatomy 0.000 description 5
- 206010047249 Venous thrombosis Diseases 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 239000003146 anticoagulant agent Substances 0.000 description 4
- 210000004204 blood vessel Anatomy 0.000 description 4
- 230000000857 drug effect Effects 0.000 description 4
- 239000000706 filtrate Substances 0.000 description 4
- 239000002574 poison Substances 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 230000004913 activation Effects 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 230000002785 anti-thrombosis Effects 0.000 description 3
- 210000000589 cicatrix Anatomy 0.000 description 3
- 230000004087 circulation Effects 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 230000008034 disappearance Effects 0.000 description 3
- 239000002934 diuretic Substances 0.000 description 3
- 230000001882 diuretic effect Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000007613 environmental effect Effects 0.000 description 3
- 230000023597 hemostasis Effects 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 230000002175 menstrual effect Effects 0.000 description 3
- 231100000957 no side effect Toxicity 0.000 description 3
- 231100000252 nontoxic Toxicity 0.000 description 3
- 230000003000 nontoxic effect Effects 0.000 description 3
- 208000001297 phlebitis Diseases 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000008439 repair process Effects 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 241000736243 Pyrola rotundifolia Species 0.000 description 2
- 238000002266 amputation Methods 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 230000000916 dilatatory effect Effects 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 206010025482 malaise Diseases 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000004089 microcirculation Effects 0.000 description 2
- 239000002304 perfume Substances 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 210000003932 urinary bladder Anatomy 0.000 description 2
- 208000027185 varicose disease Diseases 0.000 description 2
- 238000012795 verification Methods 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- UPLPHRJJTCUQAY-WIRWPRASSA-N 2,3-thioepoxy madol Chemical compound C([C@@H]1CC2)[C@@H]3S[C@@H]3C[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@](C)(O)[C@@]2(C)CC1 UPLPHRJJTCUQAY-WIRWPRASSA-N 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 1
- 201000006474 Brain Ischemia Diseases 0.000 description 1
- 208000033386 Buerger disease Diseases 0.000 description 1
- 206010008120 Cerebral ischaemia Diseases 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241001633942 Dais Species 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010053155 Epigastric discomfort Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010027336 Menstruation delayed Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 206010043540 Thromboangiitis obliterans Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000000146 antalgic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000000767 anti-ulcer Effects 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000003114 blood coagulation factor Substances 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 206010008118 cerebral infarction Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000002607 hemopoietic effect Effects 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 230000002390 hyperplastic effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000001926 lymphatic effect Effects 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000011812 mixed powder Substances 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
- 229940126701 oral medication Drugs 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000002537 thrombolytic effect Effects 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a pharmaceutical composition for treatment of varicosity and a preparation method thereof. The pharmaceutical composition comprises 3-80 parts of saffron crocus by weight, 3-80 parts of olibanum by weight, 3-80 parts of myrrh by weight, 3-60 parts of radix rehmanniae by weight, 3-60 parts of radix sophorae flavescentis by weight, 6-100 parts of sangusis draconis by weight, 6-100 parts of leech by weight, 3-80 parts of leonurus by weight, 3-80 parts of waxgourd peel by weight, 3-100 parts of eupolyphaga by weight, 80-200 parts of murraya paniculata by weight, 3-80 parts of ligusticum wallichii by weight, 3-80 parts of pyrola by weight, 3-50 parts of teucrium viscidum by weight, 3-60 parts of curcuma zedoary by weight, 1-30 parts of madder, 30-80 parts of buddleja asiatica by weight, 3-60 parts of radix angelicae pubescentis by weight, 3-60 parts of cinnamon by weight, 3-100 parts of lysimachia nummularia by weight, 3-100 parts of tetrapanax papyriferus by weight, 3-80 parts of codonopsis pilosula by weight, 3-30 parts of angelica sinensis by weight, 1-30 parts of pseudo-ginseng and optional pharmaceutically acceptable excipients.
Description
Technical field
The present invention relates to a kind of pure Chinese medicinal preparation, relate in particular to a kind of cirsoid Chinese medicine preparation for the treatment of.
Background technology
Varicosis is a kind of frequently-occurring disease of common veins of lower extremity projection, and sickness rate is high, according to Chinese disease surveillance center monitors, shows, 11.6% Chinese suffer from the peripheral angiopathys such as varicosis in various degree, vasculitis, phlebitis.At China's Hospital: per hour because suffering from varicosis, there are 3 teachers will take leave of dais; Have 350 sales counter shop-assistants will lose the job post because suffering from vasculitis, phlebitis every day; Monthly because suffering from varicosis, there are 1600 soldiers, police, security personnel more to change jobs; In China, there are every year 3800000 labourers that stand to suffer from " foul disease " that varicosis, vasculitis, phlebitis etc. are often considered to " amputation " signal; It is high that numeral shows that China's peripheral angiopathy enters particularly 28 years old-55 years old outbreak period age bracket sickness rate in advance, and mostly be the good men and women of at life's full flowering sign, once morbidity gently, impact is physically and mentally healthy, heavy cause pain, swelling, the sense of heaviness difficulty of walking, skin blackout, vasculitis, phlebothrombosis, limbs fester, and treat and cause not in time amputation late period, to patient, cause great economy burden to have a strong impact on quality of life; Not only China so, peripheral angiopathy is also one and allows medical expert's world-famous puzzle at a loss what to do in the world.According to WHO(World Health Organization (WHO)) up-to-date < < whole world peripheral vascular disease report > > discloses: take thromboangiitis obliterans and varicosis wreaks havoc in the whole world in recent years as the peripheral angiopathy of leading, and seizes every year 500000 human lives and 3,000,000 shanks.Home and abroad there is no specific drug and the technology for the treatment of varicosis, vasculitis and complication non-operative treatment at present;
The cirsoid method of existing treatment mainly contains:
1, oral drugs have greatly side effect to gastric irritation, and the low recurrences that have of cure rate more;
2, differential hardening agent injection for injection sealing, sealing blood vessels, this way relapse rate of clinical proof is high, and complication is many;
3, folk prescription among the people--have some patient to take folk prescription in clinical and fail to respond to any medical treatment, the best treatment of result is missed period, the middle and advanced stage that the state of an illness is incured loss through delay poling refractory and healed;
4, operative treatment, generally to utilize modern technologies, operation to destroy merely or extract original vein at present, clinical proof operative treatment misery is larger, when after operation, walking appears in 2-3 most of patients, lower limb has sense of heaviness, minority is with pain, and relapse rate is high, expense is high, make patient endlessly sad;
5, also have cirsoid other Chinese medicine preparation for the treatment of, and method is comparatively complicated; At present home and abroad yet there are no with the pure Chinese powder medicine external application special for treating varicosis report of rehabilitation at short notice.
Therefore,, for cirsoid treatment, also need medicine and method more safely and effectively.
Summary of the invention
The object of the invention is to provide a kind of powder of pure Chinese medicine, is used for the treatment of varicosis, and application method is external application, zero distance medication, and directly to focus, no pain, zero injures, repairing performance is strong, cure rate is high, environmental protection is not recurred.
The invention provides a kind of cirsoid pharmaceutical composition that is used for the treatment of, comprising:
Stigma Croci 3-80 weight portion, Olibanum 3-80 weight portion, Myrrha 3-80 weight portion, Radix Rehmanniae 3-60 weight portion, Radix Sophorae Flavescentis 3-60 weight portion, Sanguis Draxonis 6-100 weight portion, Hirudo 6-100 weight portion, Herba Leonuri 3-80 weight portion, Exocarpium Benincasae 3-80 weight portion, Eupolyphaga Seu Steleophaga 3-100 weight portion, Folium Et Cacumen Murrayae 80-200 weight portion, Rhizoma Chuanxiong 3-80 weight portion, Herba Pyrolae 3-80 weight portion, Herba Chenopodii Hybridi 3-50 weight portion, Rhizoma Curcumae 3-60 weight portion, Radix Rubiae 1-30 weight portion, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 30-80 weight portion, Radix Angelicae Pubescentis 3-60 weight portion, Cortex Cinnamomi 3-60 weight portion, Herba Lysimachiae 3-100 weight portion, Medulla Tetrapanacis 3-100 weight portion, Radix Codonopsis 3-80 weight portion, Radix Angelicae Sinensis 3-30 weight portion and Radix Notoginseng 1-30 weight portion, and optional pharmaceutically useful adjuvant.This pharmaceutical composition can effectively be treated varicosis, no pain, and through affected part, cure rate is high.
In a preferred embodiment, described pharmaceutical composition comprises Stigma Croci 15-30 weight portion, Olibanum 15-30 weight portion, Myrrha 15-30 weight portion, Radix Rehmanniae 15-25 weight portion, Radix Sophorae Flavescentis 15-25 weight portion, Sanguis Draxonis 25-35 weight portion, Hirudo 25-35 weight portion, Herba Leonuri 15-30 weight portion, Exocarpium Benincasae 15-30 weight portion, Eupolyphaga Seu Steleophaga 40-60 weight portion, Folium Et Cacumen Murrayae 80-90 weight portion, Rhizoma Chuanxiong 15-30 weight portion, Herba Pyrolae 15-30 weight portion, Herba Chenopodii Hybridi 10-20 weight portion, Rhizoma Curcumae 15-30 weight portion, Radix Rubiae 5-10 weight portion, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 30-50 weight portion, Radix Angelicae Pubescentis 15-30 weight portion, Cortex Cinnamomi 15-30 weight portion, Herba Lysimachiae 20-50 weight portion, Medulla Tetrapanacis 20-50 weight portion, Radix Codonopsis 15-30 weight portion, Radix Angelicae Sinensis 15-25 weight portion and Radix Notoginseng 5-10 weight portion, and optional pharmaceutically acceptable auxiliaries.For different patients, according to the concrete condition of its four methods of diagnosis, can finely tune medicament contg, but not exceed in above-mentioned content and proportion.
In a preferred embodiment, the described Folium Et Cacumen Murrayae described in cirsoid pharmaceutical composition that is used for the treatment of spends for steeping 55 the medicinal residues that obtain after above Chinese liquor.Those skilled in the art can rule of thumb soak Folium Et Cacumen Murrayae according to this area conventional means.Folium Et Cacumen Murrayae: the immersion part by weight of Chinese liquor can be preferably 1:1 to 1:6, more preferably 1:4.
In a preferred embodiment, further comprise the medicated wine obtaining by soaking Folium Et Cacumen Murrayae.
In further preferred embodiment, the described amount that is used for the treatment of medicated wine described in cirsoid pharmaceutical composition is 60 to 70 weight portions.
The present invention also provides a kind of cirsoid pharmaceutical composition that is used for the treatment of, and by the compositions and the pharmaceutically useful adjuvant that comprise following traditional Chinese medicines material, as raw material, is prepared:
Stigma Croci 3-80 weight portion, Olibanum 3-80 weight portion, Myrrha 3-80 weight portion, the Radix Rehmanniae-60 weight portion, Radix Sophorae Flavescentis 3-60 weight portion, Sanguis Draxonis 6-100 weight portion, Hirudo 6-100 weight portion, Herba Leonuri 3-80 weight portion, Exocarpium Benincasae 3-80 weight portion, Eupolyphaga Seu Steleophaga 3-100 weight portion, Folium Et Cacumen Murrayae 80-200 weight portion, Rhizoma Chuanxiong 3-80 weight portion, Herba Pyrolae 3-80 weight portion, Herba Chenopodii Hybridi 3-50 weight portion, Rhizoma Curcumae 3-60 weight portion, Radix Rubiae 1-30 weight portion, the little 30-80 weight portion of reviving after death, Radix Angelicae Pubescentis 3-60 weight portion, Cortex Cinnamomi 3-60 weight portion, Herba Lysimachiae 3-100 weight portion, Medulla Tetrapanacis 3-100 weight portion, Radix Codonopsis 3-80 weight portion, Radix Angelicae Sinensis 3-30 weight portion, Radix Notoginseng 1-30 weight portion.For different patients, according to the concrete condition of its four methods of diagnosis, can finely tune medicament contg, but not exceed in above-mentioned content and proportion.
One preferred embodiment in, described raw material comprises Stigma Croci 15-30 weight portion, Olibanum 15-30 weight portion, Myrrha 15-30 weight portion, Radix Rehmanniae 15-25 weight portion, Radix Sophorae Flavescentis 15-25 weight portion, Sanguis Draxonis 25-35 weight portion, Hirudo 25-35 weight portion, Herba Leonuri 15-30 weight portion, Exocarpium Benincasae 15-30 weight portion, Eupolyphaga Seu Steleophaga 40-60 weight portion, Folium Et Cacumen Murrayae 80-90 weight portion, Rhizoma Chuanxiong 15-30 weight portion, Herba Pyrolae 15-30 weight portion, Herba Chenopodii Hybridi 10-20 weight portion, Rhizoma Curcumae 15-30 weight portion, Radix Rubiae 5-10 weight portion, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 30-50 weight portion, Radix Angelicae Pubescentis 15-30 weight portion, Cortex Cinnamomi 15-30 weight portion, Herba Lysimachiae 20-50 weight portion, Medulla Tetrapanacis 20-50 weight portion, Radix Codonopsis 15-30 weight portion, Radix Angelicae Sinensis 15-25 weight portion and Radix Notoginseng 5-10 weight portion, and optional pharmaceutically acceptable auxiliaries.
Preferably, described be used for the treatment of cirsoid pharmaceutical composition, further comprise the medicated wine obtaining by soaking Folium Et Cacumen Murrayae.Described medicated wine is preferably 60 to 70 weight portions.
The present invention also provides a kind of method for the preparation of the cirsoid pharmaceutical composition for the treatment of, comprising:
Adopt Stigma Croci 3-80 weight portion, Olibanum 3-80 weight portion, Myrrha 3-80 weight portion, Radix Rehmanniae 3-60 weight portion, Radix Sophorae Flavescentis 3-60 weight portion, Sanguis Draxonis 6-100 weight portion, Hirudo 6-100 weight portion, Herba Leonuri 3-80 weight portion, Exocarpium Benincasae 3-80 weight portion, Eupolyphaga Seu Steleophaga 3-100 weight portion, Folium Et Cacumen Murrayae 80-200 weight portion, Rhizoma Chuanxiong 3-80 weight portion, Herba Pyrolae 3-80 weight portion, Herba Chenopodii Hybridi 3-50 weight portion, Rhizoma Curcumae 3-60 weight portion, Radix Rubiae 1-30 weight portion, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 30-80 weight portion, Radix Angelicae Pubescentis 3-60 weight portion, Cortex Cinnamomi 3-60 weight portion, Herba Lysimachiae 3-100 weight portion, Medulla Tetrapanacis 3-100 weight portion, Radix Codonopsis 3-80 weight portion, Radix Angelicae Sinensis 3-30 weight portion and Radix Notoginseng 1-30 weight portion are as raw material,
By above-mentioned weight proportion, various Chinese crude drug Preparation process are ground and make powder, then fully mix;
Wherein said Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) soaks to dry with Chinese liquor and grinds afterwards again; And
Wherein said Folium Et Cacumen Murrayae is that the medicinal residues after steeping in wine dry and grind.These treatment process of steeping in wine have guaranteed the shelf-life of medicine.Wherein the weight ratio of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) and Chinese liquor can rule of thumb be determined by those skilled in the art, and preferably soaking the Chinese liquor of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) and the weight ratio of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) is 1:1 to 1:6, preferably 1:4.
Preferably, the weight ratio of described Folium Et Cacumen Murrayae and Chinese liquor is 1:1 to 1:6, preferably 1:4.
In a preferred embodiment, described method further comprises the step of the medicated wine modulation that described powder is obtained by immersion Folium Et Cacumen Murrayae.By powder of the present invention with described medicated wine according to 1:1 to 1:6, preferably 1:1 to 1:4, more preferably the part by weight furnishing thick paste of 1:1.2.
The pharmaceutical composition that the present invention also provides method as above to prepare.
The present invention be record prescription reach the treatment varicosis of grasping 777 after effective outside coating method, the present invention is through groping, studying for many years, through clinical verification, therapeutic process is simple, no pain zero injury, special effect cure rate is high, does not recur the pure Chinese medicinal preparation that expense is low.
Designing requirement the present invention reaches following therapeutic effect: qi and blood circulation promotion, the meridian dredging, and hard masses softening and resolving, Xuemaitong, without additional any treatment means, safety and environmental protection pure Chinese medicinal preparation; Therapeutic process is simple, and do not have an injection and do not take medicine, do not affect work, study, life, zero distance medication directly to focus, no pain zero injury, one-time cure does not recur.
Patent clinical therapeutic efficacy of the present invention is as follows: this preparation have repair because of pachylosis that varicosis, vasculitis, phlebothrombosis cause, fester, cicatrix, a medication 3-7 days pain symptom disappears substantially, medication sense of heaviness disappearance on foot in 15 days to 30 days, common disease is almost recovered for 30 days, the heavier patient's medication of state of an illness recovery from illness in 45 days to 60 days, does not recur and has no side effect.
The specific embodiment
The following term using in this description has implication hereinafter described.Except as otherwise noted, all scientific and technical terminologies used herein have the implication identical with the common understanding of those of ordinary skills.
For realizing the object of the invention, technical solution of the present invention is as follows:
The present invention contains 24 kinds of Chinese crude drug preparations and makes external pulvis, forms with adjuvant, it is characterized in that the pure Chinese medicine of the drug weight percentage ratio that this external preparation contains 40%-70%, and the outer used time adds medicine ethanol in this powder; 24 kinds of Chinese crude drugs are as follows: Stigma Croci, Olibanum, Myrrha, the Radix Rehmanniae (Radix Rehmanniae), Radix Sophorae Flavescentis, Sanguis Draxonis, Hirudo, Herba Leonuri, Exocarpium Benincasae, Eupolyphaga Seu Steleophaga, Folium Et Cacumen Murrayae, Rhizoma Chuanxiong, Herba Pyrolae (Pyrola rotundifolia ssp.chinensis), Herba Chenopodii Hybridi, Rhizoma Curcumae, Radix Rubiae, little reviving after death (Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)), Radix Angelicae Pubescentis, Cortex Cinnamomi, Herba Lysimachiae (BIANDIXIANG), Medulla Tetrapanacis, Radix Codonopsis, Radix Angelicae Sinensis, Radix Notoginseng; By said ratio, various Chinese crude drug Preparation process are ground and make powder, with medicated wine furnishing paste, dormant various compositions are activated, directly spread on affected part and wrap up with gauze bandage, 15 days drug effect phases.
The clinical good effect of the present invention:
Through clinical verification preparation of the present invention, have and attack long-pending, reparation, infiltration, Yin Yang balancing, enter the feature that inner absorbability is strong, can promote local cells to organize new old generation to let out, can dissolve rapidly and remove phlebothrombosis and venous blood tube wall deposition residues, can activate cells of vascular wall reparation wall film, can repair and protrude Superficial veins, life, recovery skin true qualities by Yin Yang balancing, varicosis and complication are had to magical curative effect.
Clinical therapeutic efficacy of the present invention is as follows: this preparation have repair because of pachylosis that varicosis, vasculitis, phlebothrombosis cause, fester, cicatrix, a medication 3-7 days pain symptom disappears substantially, medication sense of heaviness disappearance on foot in 15 days to 30 days, common disease is almost recovered for 30 days, the heavier patient's medication of state of an illness recovery from illness in 45 days to 60 days, does not recur and has no side effect.
In preparation of the present invention, Stigma Croci, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, warm in nature, enters the heart, Liver Channel; Olibanum, Myrrha, detumescence life invigorates blood circulation, loose blood, blood stasis dispelling, chase after poison, damp-clearing pain-relieving, " acrid in the mouth, hot in nature, micro-poison.Acrid in the mouth, warm in nature nontoxic ", enter the heart, liver, spleen channel.Enter spleen, kidney channel; Sanguis Draxonis, blood circulation promoting and blood stasis dispelling circulation of qi promoting, reducing swelling and alleviating pain, astringing to arrest bleeding, the effects such as hard masses softening and resolving, promoting tissue regeneration and ulcer healing.Modern medicine study confirms, Sanguis Draxonis has the body of improvement microcirculation, endocrine regulation, the increase body intravascular coagulation factor and has remarkable anastalsis, aspect Chinese traditional treatment mass formed by blood stasis, there is Yin Yang balancing dual regulation, adjusting body metabolism, there is powerful anti-inflammatory and antalgic putrefaction-removing granulation-promoting and accelerate lymphatic return and improve the effects such as body's immunity.Warm in nature, flat, sweet in the mouth, salty, nontoxic, enter lung, spleen, kidney three warps; Hirudo, salty in the mouth, hardship, property is flat, nontoxic.Return Liver Channel.Kind removing blood stasis divides the stasis of blood stagnant and detumescence removing blood stasis antithrombotic; Herba Leonuri, promoting blood circulation to restore menstrual flow diuretic removing heat from blood antithrombotic, acrid in the mouth, micro-hardship, is slightly cold.GUIXIN, liver, urinary bladder channel; Rhizoma Chuanxiong, acrid in the mouth, micro-perfume (or spice), warm in nature.Enter the heart, liver, gallbladder meridian.Blood circulation promoting and blood stasis dispelling antiinflammatory dredging collateral, wind-expelling pain-stopping; Herba Pyrolae (Pyrola rotundifolia ssp.chinensis), antibacterial, heart tonifying, blood vessel dilating, wind-damp dispelling invigorating the liver and kidney.Bitter in the mouth, warm in nature, enters liver, kidney channel; Rhizoma Curcumae, the pain relieving of circulation of qi promoting removing blood stasis removing food stagnancy.Acrid in the mouth, hardship, warm in nature, enter liver, spleen channel; Folium Et Cacumen Murrayae (pharmacy wine, slag external application), promoting flow of QI and blood, expelling wind and removing dampness, detumescence poison only skin is itched, promoting blood circulation to remove blood stasis, wind-expelling pain-stopping.Acrid in the mouth, hardship, warm in nature, enter the heart, liver, lung meridian; Herba Chenopodii Hybridi, bitter in the mouth, micro-pungent, property is flat, enters Liver Channel.Heat-clearing and toxic substances removing; Expelling wind and removing dampness; Promoting blood circulation and hemostasis; Eupolyphaga Seu Steleophaga, cold in nature, salty in the mouth, poisonous, enter the heart, liver, spleen channel.There is removing blood stasis, removing mass, dredging collateral, reason wound, reducing swelling and alleviating pain, stimulating milk secretion is stimulated the menstrual flow and can thrombolytic; Radix Codonopsis, invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, QI invigorating is enriched blood again and is had the effect of antiulcer.Nature and flavor are sweet flat, enter spleen, lung meridian; The Radix Rehmanniae (Radix Rehmanniae), nature and flavor, sweet, bitter, cold, enter the heart, liver, kidney channel.Clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; Radix Sophorae Flavescentis. bitter in the mouth, cold in nature.Enter the heart, liver, large intestine, small intestinal, stomach warp.Heat clearing and damp drying, diuretic, anti-inflammation; Little reviving after death (Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)), acrid in the mouth, hardship, property is flat.Enter liver, kidney, lung meridian.Wind-damp dispelling, dissipating blood stasis blood; Radix Rubiae, bitter in the mouth, cold in nature.Enter Liver Channel.The effect that has cooling blood for hemostasis, blood stasis dispelling; Exocarpium Benincasae. sweet in the mouth, cold nature, enters lung, spleen, small intestine meridian.Clearing away heat and promoting diuresis, damp eliminating chase after wind, profit skin; Radix Angelicae Pubescentis, taste, pungent, bitter, warm in nature, enter bladder, liver, kidney channel.Have that dispersing wind and cold is wet, the effect of pain relieving, blood vessel dilating; Cortex Cinnamomi, warming spleen and stomach for dispelling cold, promoting the flow of QI-blood by warming the meridian.Taste, pungent, sweet, hot in nature.Enter kidney, spleen, the heart, Liver Channel; Herba Lysimachiae (BIANDIXIANG), slightly cool in nature, sweet in the mouth perfume.Suppressing the hyperactive liver fire, clearing heat in QI system are warm, diuretic, treating stranguria, the meridian dredging; Radix Angelicae Sinensis, sweet in the mouth, pungent, warm in nature.Enter liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, inducing menstruation to relieve menalgia, loosening bowel to relieve constipation; Radix Notoginseng, has and seeks hemostasis, the clots absorbing of promoting blood circulation, and antithrombotic, promotes hemopoietic, and antiinflammatory, protects the liver, and antitumor expands blood vessel, blood pressure lowering, resists myocardial ischemia, the effect such as anti-cerebral ischemia, arrhythmia, atherosclerosis, analgesia; Medulla Tetrapanacis, sweet in the mouth, light, cold nature, enters lung, stomach warp.There is clearing away heat and promoting diuresis, promote qi circulation opening feeling pulse effect.
Select medicine, select the measured pharmacopoeia of original producton location matter, medical material is cleaned and dried oven dry, according to percentage by weight, accurately make up a prescription, pulverize and grind, bottle standby.
2, adopt the present invention to treat varicosis clinical treatment standard as follows:
Cure: use preparation of the present invention 30 days-60 days, transference cure, no recurrence of check after 11 months.
Effective: use preparation of the present invention 30 days-45 days, transference cure, check after 11 months, there is very light symptoms in former scope of medication periphery.
Invalid: to use preparation of the present invention 30 days-60 days, have no nonresponder.
Points for attention: this preparation is external only, please don't be oral, anemia of pregnant woman's forbidding; There are no skin allergy person; 3 years lower effect duration of finished product preparation air-proof condition.
The preparation method of pharmaceutical composition of the present invention, is characterized in that described pharmaceutical composition comprises 24 kinds of Chinese crude drug mixed powders, medicated wine, and described powder of the present invention adopts following manufacture method to make:
Raw material: Stigma Croci 3-80 weight portion, Olibanum 3-80 weight portion, Myrrha 3-80 weight portion, Radix Rehmanniae 3-60 weight portion, Radix Sophorae Flavescentis 3-60 weight portion, Sanguis Draxonis 6-100 weight portion, Hirudo 6-100 weight portion, Herba Leonuri 3-80 weight portion, Exocarpium Benincasae 3-80 weight portion, Eupolyphaga Seu Steleophaga 3-100 weight portion, Folium Et Cacumen Murrayae 80-200 weight portion (is steep in wine, slag is used as medicine) Rhizoma Chuanxiong 3-80 weight portion, Herba Pyrolae 3-80 weight portion, Herba Chenopodii Hybridi 3-50 weight portion, Rhizoma Curcumae 3-60 weight portion, Radix Rubiae 1-30 weight portion, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 30-80 weight portion, Radix Angelicae Pubescentis 3-60 weight portion, Cortex Cinnamomi 3-60 weight portion, Herba Lysimachiae 3-100 weight portion, Medulla Tetrapanacis 3-100 weight portion, Radix Codonopsis 3-80 weight portion, Radix Angelicae Sinensis 3-30 weight portion, Radix Notoginseng 1-30 weight portion,
By above-mentioned weight proportion, various Chinese crude drug Preparation process are ground and make powder, then fully mix bottling standby.
By Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 30-80 weight portion, with Chinese liquor, soak to dry to grind and be used as medicine.
Folium Et Cacumen Murrayae 80-200 gram, 500 milliliters of the above Chinese liquor of 55 degree, are immersed in Folium Et Cacumen Murrayae in Chinese liquor and soak 48 hours, and then wine being filtered bottling standby is medicated wine; Folium Et Cacumen Murrayae medicinal residues dry to grind and are used as medicine.
While giving patient's external application, with medicated wine, powder furnishing paste of the present invention is activated dormant various compositions, directly spread on affected part and wrap up with gauze bandage, 15 days drug effect phases.
Compared with prior art, the advantage of this patent is as follows:
1, safety: it is three minutes poison of medicine that oral medicine all has sense of discomfort, operative treatment has destroyed microcirculation and the misery of diseased region, and the present invention " a kind of treat cirsoid pure Chinese powder medicine " preparation has no side effect, therapeutic process is not simply had an injection and is not taken medicine, a drug medicine 15 days action periods is directly to focus, no pain zero injury, special effect cure rate is high, does not recur, pure Chinese medicinal preparation, safety and environmental protection.
2, convenient: remove patient from and go to hospital to see doctor, have an injection, perform an operation, making up the prescription boils medicine waits complex treatment process, can oneself use with powder treatment patient of the present invention, and the treatment works well.
3, save time economical: treatment varicosis and complication mostly need several courses for the treatment of, several thousand yuan at least of expenses, ten thousand yuan at most, and relapse rate is high; Preparation a drug of the present invention (external application) drug effect can reach 15 days, and 4 costs of changing dressings two courses for the treatment of only need more than 1,000 yuan, and do not affect work and study.
4, evident in efficacy: general patient only needs medication to 45 days, just can fully recover for 30 days, heavier patient's vasculitis, skin ulceration, pain, the serious skin blackout of vein projection also only needs medication to 60 days, just can fully recover for 45 days, and special effect cure rate is high, does not recur.
5, pure Chinese medicinal preparation therapeutic modality design of the present invention has novelty, practicality, and inner disease outer treat process is simple, domestic initiation is advanced in the world, has excited patient's resist the disease spirit and resistance against diseases.
Below with specific embodiment description technical scheme of the present invention and technique effect.
Embodiment 1: take 1 gram of 80 grams of 3 grams of Stigma Crocis, 3 grams of Olibanums, 3 grams of Myrrhas, 3 grams, the Radix Rehmanniae, 3 grams of Radix Sophorae Flavescentiss, 6 grams of Sanguis Draxonis, 6 grams of Hirudos, 3 grams of Herba Leonuris, 3 grams of Exocarpium Benincasaes, 3 grams of Eupolyphaga Seu Steleophagas, Folium Et Cacumen Murrayae (steep in wine, slag be used as medicine), 3 grams of Rhizoma Chuanxiongs, 3 grams of Herba Pyrolaes, 3 grams of Herba Chenopodii Hybridis, 3 grams of Rhizoma Curcumae, 1 gram, Radix Rubiae, 30 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s, 3 grams of Radix Angelicae Pubescentiss, 3 grams of Cortex Cinnamomis, 3 grams of Herba Lysimachiaes, 3 grams of Medulla Tetrapanaciss, 3 grams of Radix Codonopsis, 3 grams of Radix Angelicae Sinensis and Radix Notoginseng, these Chinese crude drug Preparation process that take are ground to form to powder, then repeat to mix, bottle standby.Wherein, 30 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s are soaked with Chinese liquor, dry rear grinding and be used as medicine; Folium Et Cacumen Murrayae is immersed in Chinese liquor to 48 hours, filters, filtrate bottling is standby, i.e. medicated wine; Folium Et Cacumen Murrayae medicinal residues dry to grind and are used as medicine.
Usage: the medicated wine modulation that described powder is obtained by immersion Folium Et Cacumen Murrayae: use medicated wine according to the part by weight furnishing thick paste of 1:1.2 part this powder, affected part is cleaned, spread on affected part thickness 3-5 millimeter, area is limited with projection or swelling scope, it is suitable around wrapping, elasticity first with gauze shawl, to hold with gauze bandage again, within 15th, change dressings one time 30 days be a course for the treatment of.
Embodiment 2
80 grams of 15 grams of Stigma Crocis, 15 grams of Olibanums, 15 grams of Myrrhas, 15 grams, the Radix Rehmanniae, 15 grams of Radix Sophorae Flavescentiss, 25 grams of Sanguis Draxonis, 25 grams of Hirudos, 15 grams of Herba Leonuris, 15 grams of Exocarpium Benincasaes, 40 grams of Eupolyphaga Seu Steleophagas, Folium Et Cacumen Murrayae (steep in wine, slag be used as medicine), 15 grams of Rhizoma Chuanxiongs, 15 grams of Herba Pyrolaes, 10 grams of Herba Chenopodii Hybridis, 15 grams of Rhizoma Curcumae, 5 grams, Radix Rubiae, 30 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s, 15 grams of Radix Angelicae Pubescentiss, 15 grams of Cortex Cinnamomis, 20 grams of Herba Lysimachiaes, 20 grams of Medulla Tetrapanaciss, 15 grams of Radix Codonopsis, 15 grams of Radix Angelicae Sinensis, 5 grams of Radix Notoginseng, these Chinese crude drug Preparation process that take are ground to form to powder, then repeat to mix, bottle standby.
Note: 30 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s are soaked with 30 milliliters of 55 degree Chinese liquor, dry rear grinding and be used as medicine;
By 80 grams of Folium Et Cacumen Murrayae, get 320 milliliters of 55 degree Chinese liquor, Folium Et Cacumen Murrayae is immersed in Chinese liquor to 48 hours, to filter, filtrate bottling is standby, i.e. medicated wine; Folium Et Cacumen Murrayae medicinal residues dry to grind and are used as medicine.
Usage: give patient's external application get it filled 160 milliliters of wine, will dormant various compositions activation with medicated wine furnishing paste by 130 grams of powders of the present invention, affected part is cleaned, spread on affected part, thickness 3-5 millimeter, area is limited with projection or swelling scope, it is suitable around wrapping, elasticity first with gauze shawl, to hold with gauze bandage again, within 15th, change dressings one time 30 days be a course for the treatment of;
While giving patient's external application, with medicated wine 40%-60%, powder furnishing paste of the present invention is activated dormant various compositions, directly spread on affected part and wrap up with gauze bandage, 15 days drug effect phases.
Embodiment 3: 200 grams of 80 grams of Stigma Crocis, 80 grams of Olibanums, 80 grams of Myrrhas, 60 grams, the Radix Rehmanniae, 60 grams of Radix Sophorae Flavescentiss, 100 grams of Sanguis Draxonis, 100 grams of Hirudos, 80 grams of Herba Leonuris, 80 grams of Exocarpium Benincasaes, 100 grams of Eupolyphaga Seu Steleophagas, Folium Et Cacumen Murrayae (steep in wine, slag be used as medicine), 80 grams of Rhizoma Chuanxiongs, 80 grams of Herba Pyrolaes, 50 grams of Herba Chenopodii Hybridis, 60 grams of Rhizoma Curcumae, 30 grams, Radix Rubiae, 80 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s, 60 grams of Radix Angelicae Pubescentiss, 60 grams of Cortex Cinnamomis, 100 grams of Herba Lysimachiaes, 100 grams of Medulla Tetrapanaciss, 80 grams of Radix Codonopsis, 30 grams of Radix Angelicae Sinensis, 30 grams of Radix Notoginseng.
Usage is identical with embodiment 1.
Embodiment 4,
10 grams of 30 grams of Stigma Crocis, 30 grams of Olibanums, 30 grams of Myrrhas, 25 grams, the Radix Rehmanniae, 25 grams of Radix Sophorae Flavescentiss, 35 grams of Sanguis Draxonis, 35 grams of Hirudos, 30 grams of Herba Leonuris, 30 grams of Exocarpium Benincasaes, 60 grams of Eupolyphaga Seu Steleophagas, 90 grams of Folium Et Cacumen Murrayae, 30 grams of Rhizoma Chuanxiongs, 30 grams of Herba Pyrolaes, 20 grams of Herba Chenopodii Hybridis, 10 grams of Rhizoma Curcumae, 10 grams, Radix Rubiae, 50 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s, 30 grams of Radix Angelicae Pubescentiss, 30 grams of Cortex Cinnamomis, 50 grams of Herba Lysimachiaes, 50 grams of Medulla Tetrapanaciss, 30 grams of Radix Codonopsis, 25 grams of Radix Angelicae Sinensis and Radix Notoginseng, these Chinese crude drug Preparation process that take are ground to form to powder, then repeat to mix, bottle standby.
Note: 50 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s are soaked with 40 milliliters of 61 degree Chinese liquor, dry rear grinding and be used as medicine;
By 90 grams of Folium Et Cacumen Murrayae, get 350 milliliters of 55 degree Chinese liquor, Folium Et Cacumen Murrayae is immersed in Chinese liquor to 48 hours, to filter, filtrate bottling is standby, i.e. medicated wine; Folium Et Cacumen Murrayae medicinal residues dry to grind and are used as medicine.
Give patient's external application get it filled 180 milliliters of wine, will dormant various compositions activation with medicated wine furnishing paste by 160 grams of powders of the present invention, affected part is cleaned, spread on affected part, thickness 3-5 millimeter, area is limited with projection or swelling scope, it is suitable around wrapping, elasticity first with gauze shawl, to hold with gauze bandage again, within 15th, change dressings one time 30 days be a course for the treatment of;
Embodiment 5:
7 grams of 23 grams of Stigma Crocis, 23 grams of Olibanums, 23 grams of Myrrhas, 20 grams, the Radix Rehmanniae, 20 grams of Radix Sophorae Flavescentiss, 30 grams of Sanguis Draxonis, 30 grams of Hirudos, 23 grams of Herba Leonuris, 23 grams of Exocarpium Benincasaes, 50 grams of Eupolyphaga Seu Steleophagas, 85 grams of Folium Et Cacumen Murrayae, 23 grams of Rhizoma Chuanxiongs, 23 grams of Herba Pyrolaes, 15 grams of Herba Chenopodii Hybridis, 23 grams of Rhizoma Curcumae, 8 grams, Radix Rubiae, 40 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s, 23 grams of Radix Angelicae Pubescentiss, 23 grams of Cortex Cinnamomis, 35 grams of Herba Lysimachiaes, 35 grams of Medulla Tetrapanaciss, 23 grams of Radix Codonopsis, 20 grams of Radix Angelicae Sinensis and Radix Notoginseng, these Chinese crude drug Preparation process that take are ground to form to powder, then repeat to mix, bottle standby.
Note: 40 grams of Herba Gendarussae (Caulis et Folium Gendarussae vulgaris)s are soaked with 40 milliliters of 55 degree Chinese liquor, dry rear grinding and be used as medicine;
By 85 grams of Folium Et Cacumen Murrayae, get 340 milliliters of 55 degree Chinese liquor, Folium Et Cacumen Murrayae is immersed in Chinese liquor to 48 hours, to filter, filtrate bottling is standby, i.e. medicated wine; Folium Et Cacumen Murrayae medicinal residues dry to grind and are used as medicine.
Give patient's external application get it filled 260 milliliters of wine, will dormant various compositions activation with medicated wine furnishing paste by 200 grams of powders of the present invention, affected part is cleaned, spread on affected part, thickness 3-5 millimeter, area is limited with projection or swelling scope, it is suitable around wrapping, elasticity first with gauze shawl, to hold with gauze bandage again, within 15th, change dressings one time 30 days be a course for the treatment of;
The medicine of preparing in above-described embodiment is used for the treatment of to following patient, and effect is as described below.
See table 1,218 people such as Fu (man), Lee (female) are peripheral angiopathy varicosis through hospital diagnosis above county level, from 2009 to 2011 triennial by the treatment clinical observation to 218 people such as Fu (man), Lee (female), clinical experiment result is: be effectively always 218 people, total effective rate 100%, curing number is 216 people, cure rate 99.1%, and invalid number is 0.
Table 1
Model case: Fu, man, 82 years old, beautiful people from community in Nangong City, two varicose veins of the lower extremity medical histories, more than 53 years, have operative treatment history in 1975, and the spring in 2009 is used the prescription treatment of the embodiment of the present invention 5, does not occur varicosis disease again.
Lee, the male ，48Sui， Inner Mongol bannerman of Oroqen, left lower extremity was suffered from varicosis more than 15 years, was afraid of cool autumn and winter of lower limb hurt like hell, and the sense of heaviness of walking is serious, from early winter in 2009, using embodiments of the invention 2 treatments,, there is not varicosis disease in the medication recovery from illness in 45 days that is just eased two days later so far.
The Xu Zhuan village people of Wang ，Nan ，50Sui， Jizhou City, right lower extremity varicosis medical history more than 20 years, vein projection is serious at one's knees, and pars affecta skin is black, has the cicatrix of festering, from the winter in 2010, use embodiments of the invention 3 treatment recovery from illness in 60 days, fester disappearance, Hyperplastic Scars, so far not recurrence.
Lee ，Nv ，73Sui， Jizhou City people from Families Home of government, existing more than 30 years of two varicose veins of the lower extremity, are used embodiments of the invention 4 treatment recovery from illness in 60 days in the early spring in 2011, not recurrence so far.
From above-mentioned case, pharmaceutical composition of the present invention can effectively be treated varicosis, and have easy to use, do not recur, with low cost, the painless advantage of waiting bitterly for of patient.
Although aforementioned embodiments of the present invention has been described with reference to above-mentioned each embodiment and case, the present invention is not limited to these embodiments and can various form implements.It will be understood by those skilled in the art that in description, illustrate, do not changing under the condition of technical spirit of the present invention or basic feature, the present invention can embodied in other realize technique effect of the present invention.Therefore, should understand these embodiments be interpreted as in every respect illustrative, should with restriction mode not consider.Scope of the present invention should be limited by claims.
Claims (11)
1. be used for the treatment of a cirsoid pharmaceutical composition, comprise:
Stigma Croci 3-80 weight portion, Olibanum 3-80 weight portion, Myrrha 3-80 weight portion, Radix Rehmanniae 3-60 weight portion, Radix Sophorae Flavescentis 3-60 weight portion, Sanguis Draxonis 6-100 weight portion, Hirudo 6-100 weight portion, Herba Leonuri 3-80 weight portion, Exocarpium Benincasae 3-80 weight portion, Eupolyphaga Seu Steleophaga 3-100 weight portion, Folium Et Cacumen Murrayae 80-200 weight portion, Rhizoma Chuanxiong 3-80 weight portion, Herba Pyrolae 3-80 weight portion, Herba Chenopodii Hybridi 3-50 weight portion, Rhizoma Curcumae 3-60 weight portion, Radix Rubiae 1-30 weight portion, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 30-80 weight portion, Radix Angelicae Pubescentis 3-60 weight portion, Cortex Cinnamomi 3-60 weight portion, Herba Lysimachiae 3-100 weight portion, Medulla Tetrapanacis 3-100 weight portion, Radix Codonopsis 3-80 weight portion, the powder that Radix Angelicae Sinensis 3-30 weight portion and Radix Notoginseng 1-30 weight portion form, and
Optional pharmaceutically useful adjuvant.
2. be as claimed in claim 1ly used for the treatment of cirsoid pharmaceutical composition, comprise Stigma Croci 15-30 weight portion, Olibanum 15-30 weight portion, Myrrha 15-30 weight portion, Radix Rehmanniae 15-25 weight portion, Radix Sophorae Flavescentis 15-25 weight portion, Sanguis Draxonis 25-35 weight portion, Hirudo 25-35 weight portion, Herba Leonuri 15-30 weight portion, Exocarpium Benincasae 15-30 weight portion, Eupolyphaga Seu Steleophaga 40-60 weight portion, Folium Et Cacumen Murrayae 80-90 weight portion, Rhizoma Chuanxiong 15-30 weight portion, Herba Pyrolae 15-30 weight portion, Herba Chenopodii Hybridi 10-20 weight portion, Rhizoma Curcumae 15-30 weight portion, Radix Rubiae 5-10 weight portion, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 30-50 weight portion, Radix Angelicae Pubescentis 15-30 weight portion, Cortex Cinnamomi 15-30 weight portion, Herba Lysimachiae 20-50 weight portion, Medulla Tetrapanacis 20-50 weight portion, Radix Codonopsis 15-30 weight portion, the powder of Radix Angelicae Sinensis 15-25 weight portion and Radix Notoginseng 5-10 weight portion, and
Optional pharmaceutically acceptable auxiliaries.
3. be as claimed in claim 1 or 2ly used for the treatment of cirsoid pharmaceutical composition, the medicinal residues of wherein said Folium Et Cacumen Murrayae for obtaining after the above Chinese liquor of bubble 55 degree.
4. be as claimed in claim 3ly used for the treatment of cirsoid pharmaceutical composition, wherein further comprise the medicated wine obtaining by soaking Folium Et Cacumen Murrayae.
5. be as claimed in claim 4ly used for the treatment of cirsoid pharmaceutical composition, the weight ratio of wherein said medicated wine and described powder is in the scope of 1:1 to 1:6.
6. be used for the treatment of a cirsoid pharmaceutical composition, by compositions and the pharmaceutically useful adjuvant of following traditional Chinese medicines material, as raw material, prepared:
Stigma Croci 3-80 weight portion, Olibanum 3-80 weight portion, Myrrha 3-80 weight portion, the Radix Rehmanniae-60 weight portion, Radix Sophorae Flavescentis 3-60 weight portion, Sanguis Draxonis 6-100 weight portion, Hirudo 6-100 weight portion, Herba Leonuri 3-80 weight portion, Exocarpium Benincasae 3-80 weight portion, Eupolyphaga Seu Steleophaga 3-100 weight portion, Folium Et Cacumen Murrayae 80-200 weight portion, Rhizoma Chuanxiong 3-80 weight portion, Herba Pyrolae 3-80 weight portion, Herba Chenopodii Hybridi 3-50 weight portion, Rhizoma Curcumae 3-60 weight portion, Radix Rubiae 1-30 weight portion, the little 30-80 weight portion of reviving after death, Radix Angelicae Pubescentis 3-60 weight portion, Cortex Cinnamomi 3-60 weight portion, Herba Lysimachiae 3-100 weight portion, Medulla Tetrapanacis 3-100 weight portion, Radix Codonopsis 3-80 weight portion, Radix Angelicae Sinensis 3-30 weight portion, Radix Notoginseng 1-30 weight portion.
7. be as claimed in claim 6ly used for the treatment of cirsoid pharmaceutical composition, further comprise the medicated wine obtaining by soaking Folium Et Cacumen Murrayae, the weight ratio of described medicated wine and described powder is in the scope of 1:1 to 1:6.
8. for the preparation of a method for the cirsoid pharmaceutical composition for the treatment of, comprising:
Adopt Stigma Croci 3-80 weight portion, Olibanum 3-80 weight portion, Myrrha 3-80 weight portion, Radix Rehmanniae 3-60 weight portion, Radix Sophorae Flavescentis 3-60 weight portion, Sanguis Draxonis 6-100 weight portion, Hirudo 6-100 weight portion, Herba Leonuri 3-80 weight portion, Exocarpium Benincasae 3-80 weight portion, Eupolyphaga Seu Steleophaga 3-100 weight portion, Folium Et Cacumen Murrayae 80-200 weight portion, Rhizoma Chuanxiong 3-80 weight portion, Herba Pyrolae 3-80 weight portion, Herba Chenopodii Hybridi 3-50 weight portion, Rhizoma Curcumae 3-60 weight portion, Radix Rubiae 1-30 weight portion, Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) 30-80 weight portion, Radix Angelicae Pubescentis 3-60 weight portion, Cortex Cinnamomi 3-60 weight portion, Herba Lysimachiae 3-100 weight portion, Medulla Tetrapanacis 3-100 weight portion, Radix Codonopsis 3-80 weight portion, Radix Angelicae Sinensis 3-30 weight portion and Radix Notoginseng 1-30 weight portion are as raw material,
By above-mentioned weight proportion, various Chinese crude drug Preparation process are ground and make powder, then fully mix;
Wherein said Herba Gendarussae (Caulis et Folium Gendarussae vulgaris) soaks to dry afterwards with Chinese liquor and after grinding, adds described pharmaceutical composition again;
Wherein said Folium Et Cacumen Murrayae, with after soaking in Chinese liquor, is dried the medicinal residues that obtain, then adds described pharmaceutical composition after grinding.
9. method as claimed in claim 8, the weight ratio of wherein said Folium Et Cacumen Murrayae and Chinese liquor is 1:1 to 1:6, described Chinese liquor is Chinese liquor more than 55 degree.
10. method as claimed in claim 8 or 9, further comprises the step of the medicated wine modulation that described powder is obtained by immersion Folium Et Cacumen Murrayae.
Pharmaceutical composition prepared by 11. methods as described in any one in claim 8-10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210423982.6A CN102895600B (en) | 2012-10-30 | 2012-10-30 | Pharmaceutical composition for treatment of varicosity and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210423982.6A CN102895600B (en) | 2012-10-30 | 2012-10-30 | Pharmaceutical composition for treatment of varicosity and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102895600A CN102895600A (en) | 2013-01-30 |
| CN102895600B true CN102895600B (en) | 2014-02-26 |
Family
ID=47568285
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210423982.6A Expired - Fee Related CN102895600B (en) | 2012-10-30 | 2012-10-30 | Pharmaceutical composition for treatment of varicosity and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102895600B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142884B (en) * | 2013-03-11 | 2015-04-22 | 高怀玉 | Traditional Chinese medicine for treating varicosis |
| CN104274744A (en) * | 2014-10-27 | 2015-01-14 | 哈尔滨金玉科技开发有限公司 | Pharmaceutical composition for treating varicosity and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1444952A (en) * | 2002-03-16 | 2003-10-01 | 王守卷 | Wiping and spreading tincture with wide effect and its preparing method |
-
2012
- 2012-10-30 CN CN201210423982.6A patent/CN102895600B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1444952A (en) * | 2002-03-16 | 2003-10-01 | 王守卷 | Wiping and spreading tincture with wide effect and its preparing method |
Non-Patent Citations (2)
| Title |
|---|
| 王翠莲等.血栓性静脉炎的中医药治疗概况.《内蒙古中医药》.2008,(第1期),59-61. |
| 血栓性静脉炎的中医药治疗概况;王翠莲等;《内蒙古中医药》;20080131(第1期);59-61 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102895600A (en) | 2013-01-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102327478A (en) | Pharmaceutical composition for treating burns and scalds and preparation method thereof | |
| CN105982976B (en) | Treat bone penetrating fluid of bone and joint diseases and preparation method thereof | |
| CN103417790B (en) | Traditional Chinese medicine for treatment of cerebral hemorrhage | |
| CN103239703B (en) | Traditional Chinese medicine ointment for treating scapulohumeral periarthritis and preparation method thereof | |
| CN103860591A (en) | External-use Miao medicine used for regenerating tissues to heal wound after haemorrhoid fall-off and preparation method thereof | |
| CN102552501B (en) | External traditional Chinese medicine composition for treating leukoplakia vulvae | |
| CN102309723B (en) | Traditional Chinese medicine composition for treating arthralgia and preparation method of ointment thereof | |
| CN103768531B (en) | Chinese medicine composition being used for the treatment of rheumatoid arthritis and preparation method thereof | |
| CN103845578B (en) | Treatment burn and scald, decubital ulcer, herpes zoster external-use tincture and preparation method | |
| CN102895600B (en) | Pharmaceutical composition for treatment of varicosity and preparation method thereof | |
| CN101879267B (en) | Compound tincture for treating foot helosis | |
| CN102961610B (en) | Topical paste patch | |
| CN105250712B (en) | A kind of Chinese medicine composition for treating bedsore | |
| CN103908600A (en) | Externally-applied medicine for treating rheumatoid arthritis damp-heat blockage symptom as well as preparation method and administration method thereof | |
| CN103721067B (en) | A kind of diabetic foot care Chinese medicine composition | |
| CN106074873A (en) | A kind of Chinese herbal medicine for external use formula treating burn due to hot liquid or fire and preparation method thereof | |
| CN104306741A (en) | A traditional Chinese medicine formula for treating cerebral hemorrhage | |
| CN103735928A (en) | Chinese medicinal mixture for treating perianal abscess | |
| CN104825916A (en) | Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof | |
| CN104083421A (en) | Traditional Chinese medicine ointment for treating bedsore and preparation method thereof | |
| CN103751624B (en) | A kind of medicine and preparation method for the treatment of numb limbs and tense tendons after apoplexy | |
| CN102973858A (en) | Itching-relieving anti-allergy Chinese traditional medicine compound navel patch | |
| CN102836251A (en) | External traditional Chinese medicine used for treating rectal prolapse disease | |
| CN102008527A (en) | Externally applied traditional Chinese medicine powder and ventilated paster for treating haemorrhoids | |
| CN105999165A (en) | Traditional Chinese medicine preparation for treating chronic colitis, capsule and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: BEIJING WANSHOU HUAYE TECHNOLOGY CO., LTD. Free format text: FORMER OWNER: ZHAO JINGMING Effective date: 20140820 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 053200 HENGSHUI, HEBEI PROVINCE TO: 100000 FENGTAI, BEIJING |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20140820 Address after: 100000, room 1, building 8, No. 269, Feng Feng Road, Fengtai District Science City, Beijing Patentee after: Beijing Wanshou Hua Ye science and Technology Co., Ltd. Address before: 053200, room 1, unit 1, building 282, No. 402 East Road, Jizhou, Hebei Patentee before: Zhao Jingming |
|
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140226 Termination date: 20191030 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |