CN103893488A - Chinese medicine preparation for treating migraine and preparation method thereof - Google Patents
Chinese medicine preparation for treating migraine and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicine preparation for treating migraine and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The effective ingredients of the Chinese medicine preparation are prepared from the following raw materials: Cladonia alpestris, chloranthus, crape myrtle root, salivia chinensis, loofah root, root of Dentiferous Dendropanax, euphorbia humifusa, ponceau, Vaccinium bracteatum, Cynanchum thesioides, Parthenocissus tricuspidata, Maianthemum japonicum, rupestris, Leptodermis potaninii root, Cryptotympana atrata and Ligusticum pteridophyllum. The compatibility of medicinal materials of the Chinese medicine preparation is appropriate and conforms to the theories of traditional Chinese medicine and pharmacy and modern medicine and pharmacology, and the Chinese medicine preparation has the efficacies on expelling wind, removing cold, clearing away heat, removing dampness, relaxing the muscles, stimulating the blood circulation, reinforcing qi and nourishing blood, has remarkable curative effect on various symptoms caused by migraine, has short treatment course and low cost, takes effect quickly, is safe and reliable without any toxic and side effects, is convenient to take, is easy to absorb, treats both symptoms and root causes, ensures that migraine does not relapse after being cured, and can be widely applied to clinic treatment of the migraine.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to one and treat migrainous Chinese medicine preparation and preparation method.
Background technology
The periodical attack disease of migraine Shi Yileiyou family morbidity tendency, show as paroxysmal inclined to one side side pulsatile headache, companion feels sick, vomiting and photophobia, again fall ill through one section of after date of having a rest, in quiet, dark surrounds or after sleep, headache is alleviated, can be with nerve, mental function disorder before headache occurs or when outbreak.
The migrainous cause of disease is still not clear, and migraine has genetic predisposition, and migraineur has family history, and its relatives occur that migrainous risk is 3～6 times of population.Familial hemiplegic migraine is the autosomal recessive inheritance, AR of height penetrance, and FHM-I is CACNAlA gene mutation, is positioned at 19p13; FHM-II is ATPlA2 gene mutation, is positioned at 1q2l-31; FHM-III is SCNlA gene mutation, is positioned at 2q24.Primary disease women is more than male, and how in adolescence morbidity, menstrual phase is easily shown effect, and after trimester of pregnancy or menopause, outbreak reduces or stops.This prompting E&M factor participates in migrainous morbidity.Environmental factors also participates in migrainous outbreak.Migraine can be brought out by some food and medicine.In addition, high light, overwork, stress and stress after loosen, hypersomnia or very few, fasting, anxiety, emotional lability etc. be also migrainous risk factor.
In the world wide that at present World Health Organization (WHO) lists, cause migraine in all diseases of disability to be listed as the 19th.Primary disease cause of disease complexity, modern study proposed neurogenic inflammation theory, around and the sensitization of nervus centralis sensation, neuron exaltation and voltage rely on channel abnormal, cortical spreading depression, neurotransmitter theory etc., each theory has evidence relatively reliably; Correspondingly, the medicine kind of primary disease also has a lot, but the medication effect of producing according to these theories is very limited, and the abuse of Western medicine becomes one of reason of intractable headache.
Treat migrainous medicament categories a lot, great majority western medicine, though this class medicine can be alleviated disease to a certain extent, but cure the symptoms, not the disease, conventionally need Long-term taking medicine, once the original state of an illness is just got back to again in drug withdrawal, if inappropriate medication, also may fail to respond to any medical treatment and even increase the weight of disease.Therefore research and develop the migrainous Chinese medicine of a kind of safe and effective treatment very with practical value.
Summary of the invention
The invention provides one and treat migrainous Chinese medicine preparation and preparation method; The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has effect of expelling wind and cold, removing damp-heat, relaxing muscles and tendons to promote blood circulation, benefiting QI and nourishing blood, the various symptoms that treatment migraine is caused have significant curative effect, short treating period, instant effect, safe and reliable, without any side effects, and taking convenience, be easy to absorb, with low cost, treating both the principal and secondary aspects of a disease, non-relapse after healing, can be widely used in migrainous clinical treatment.
For achieving the above object, technical scheme of the present invention is implemented as follows:
One is treated migrainous Chinese medicine preparation, and raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for migrainous Chinese medicine preparation, comprise following processing step:
(1) by Cladonia alpestris (L.) Rabenh., Caulis seu folium chloranthi spicati (Chloranthus spicatus(Thunb.) Mak.), Radix Lagerstroemia indica L., Cortex Moutan, Flos Papaveris rhoeadis, Herba Vaccinii Bracteati, Herba Cynanchi Thesioidis, hang rock wind, Radix Luculiae intermediae and cicada clean, put into container, add the distilled water of 8～10 times of amounts, soaks after 5～6 hours, boil 3～4 hours, extraction; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 DEG C, relative density is 1.10～1.13, for subsequent use;
(2) Radix Luffae is put into pot, intense fire is fried, and puts into container and carry out pulverization process after having fried, and grinds into powder, crosses 200 order fine powders, for subsequent use;
(3) Radix Dendropanacis, Radix et rhizoma smilacinae japonicae and black Rhizoma Ligustici are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
(4) Radix seu Caulis Parthenocissi tricuspidatae and Herba Artemisiae Brachylobae are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(5) above-mentioned steps (1)～(4) prepared thick paste and fine powder are mixed, make capsule, obtain the migrainous Chinese medicine preparation for the treatment of of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Cladonia alpestris (L.) Rabenh.: lightly seasoned, property is flat; Return liver, stomach warp.Suppressing the hyperactive liver and subsiding YANG, regulating menstruation, hemostasis.Be used for having a dizzy spell, hypertension, migraine, epistaxis, metrorrhagia, menoxenia, leucorrhea.
Caulis seu folium chloranthi spicati (Chloranthus spicatus(Thunb.) Mak.): acrid in the mouth, sweet, micro-puckery, warm in nature.Wind-damp dispelling, connects muscles and bones.For flu, rheumatic arthritis, traumatic injury." Luchuan book on Chinese herbal medicine " carries: " removing mass, pain relieving, hemostasis.Control traumatic injury, knife injury is hemorrhage.”
Radix Lagerstroemia indica L.: mildly bitter flavor, cold nature.Clearing away heat-damp and promoting diuresis, promoting blood circulation and hemostasis, pain relieving.Main dysentery, edema, Burning Pain." conventional glossary of Herbs and Drugs among the people " carries: " promoting the circulation of blood.”
Cortex Moutan: bitter in the mouth, cold nature; GUIXIN, liver, kidney, lung meridian.Clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, sends out speckle, tells nosebleed, and the calentura later stage, hot Fu Yin divided heating, deficiency of YIN osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury, rheumatism pyretic arthralgia." Mingyi Bielu " carries: " except seasonal epidemic pathogens headache, exopathogenic heat five kinds of over strain, consumptive disease head lumbago, wind is kept silent, insane disease." studies confirm that, Cortex Moutan all has potentiation to body fluid and cellular immunization.
Radix Luffae: sweet in the mouth, property is flat.Heat-clearing and toxic substances removing, invigorates blood circulation, dredging collateral, detumescence.Control migraine, lumbago, mastitis, acute throat trouble swells and ache, discharging fresh blood stool, anal fistula." Chongqing medical herbs " carries: " the meridian dredging, promoting the circulation of blood are subsided a swelling swollen, stimulating milk secretion.”
Radix Dendropanacis: sweet in the mouth, warm in nature.Expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation.For migraine, brachial plexus neuritis, rheumatic arthritis, rheumatoid arthritis, lumbar muscle strain, chronic lambago and skelalgia, hemiplegia, traumatic injury, bruise; External is controlled on cutter hemorrhage." Zhejiang conventional medical herbs among the people " carries: " expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation, pain relieving.”
Radix seu Caulis Parthenocissi tricuspidatae: acrid in the mouth, micro-puckery, warm in nature; Return Liver Channel.Wind-expelling pain-stopping, promoting blood circulation to remove obstruction in the collateral.Cure mainly rheumatic arthralgia, apoplexy and hemiplegia, migraine and general headache, puerperal blood stasis, the raw caking of abdomen, traumatic injury, carbuncle sore tumefacting virus, ulcer being unable to heal.Supplement to the Herbal carries: " main broken old blood, puerperal blood agglomeration, the thin damage of married woman, can not diet, has piece in abdomen; Difficulty in micturition, also under leucorrhea, it the row heart is vexed, and decoction it, also infusing drugs in wine." multiple extracorporeal bacteria inhibitor test method proves that the fresh juice of this product, water decoction, decocting ethanol extract etc. all have obvious bacteriostasis to staphylococcus aureus, Staphylococcus albus, Hemolytic streptococcus, micrococcus catarrhalis, diphtheria corynebacterium, escherichia coli, Bacillus typhi, Salmonella paratyphi, Amur dysentery bacterium, shigella flexneri, sonne bacillus, bacillus pyocyaneus, bacillus enteritidis, hog cholera Salmonella etc.
Flos Papaveris rhoeadis: bitter in the mouth, puckery, cold nature is poisonous; Return large intestine channel.Antitussive, analgesia, antidiarrheal.Main cough, migraine, stomachache, dysentery." a collection of selected materials of Jiangsu Province's Chinese herbal medicine new therapy that combines both Chinese and Western medical practices exhibition data " carries: " control dysentery.It is for oral administration at twice that Hua Wufen to money is decocted soup.”
Herba Vaccinii Bracteati: bitter in the mouth, acid, sweet, property is flat.Strong muscle QI invigorating, detumescence.Control soreness of bones and muscles, myasthenia of limbs.
Herba Cynanchi Thesioidis: sweet in the mouth, cool in nature; Return lung meridian.Tonifying the lung gas, resolving heat and reducing pathogenic fire, promoting the production of body fluid to quench thirst, anti-inflammatory analgetic.Main hyperactivity of deficient fire, has sore throat, deficiency of both vital energy and Yin, and Mental fatigue is forgetful, and fidgets due to deficiency is thirsty, dizzy insomnia, puerperal asthenia, hypogalactia.
Hang rock wind: sour in the mouth, puckery, warm in nature.Dispelling, collateral-activating, promoting blood circulation and stopping pain.For bones and muscles pain due to rheumatism, leucorrhea with red and white discharge, puerperal abdonimal pain; Fracture is controlled in external, treating swelling and pain by traumatic injury, furuncle.
Radix et rhizoma smilacinae japonicae: sweet in the mouth, hardship, warm in nature; Return liver, kidney channel.Wind-expelling pain-stopping, promoting blood circulation and detumescence.For rheumatic ostalgia, nervous headache; Mastitis are controlled in external, carbuncle furuncle and phyma poison, traumatic injury." Shaanxi Chinese herbal medicine " carries: " analgesia of dispeling the wind, fills blood, strengthening bone and muscle.Control headache, migraine, rheumatalgia, menoxenia, consumptive disease wound.”
Herba Artemisiae Brachylobae: acrid in the mouth, hardship, property is flat.Expelling wind and removing dampness, clearing heat for detumescence.Main air pain of dampness syndrome, pain, laryngopharynx swelling and pain are closed in polarization.
Radix Luculiae intermediae: puckery, micro-hardship, cool in nature; Return liver, kidney channel.Anti-inflammatory analgetic, promoting blood flow to regulate menstruation, heat-clearing and toxic substances removing.Main menoxenia, dysmenorrhea, Fengshi Guanjie pain, migraine, urinary tract infection, venom, traumatic injury, trauma infection contamination.
Cicada: salty in the mouth, sweet, cold in nature; Return liver, lung meridian.Heat clearing away, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., relieving convulsion.Main fever of children, convulsion with spasms, epilepsy, night cry, migraine." herbal classic ": " main pediatric epilepsy scared, night hoof, insane disease, cold and heat."
Black Rhizoma Ligustici: acrid in the mouth, hardship, warm in nature.Dispersing cold for relieving pain.For anemofrigid cold, headache, migraine, nervous headache, cold syndrome of the stomach pain, muscle arthralgia.
The present invention compared with prior art, has following beneficial effect:
The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has effect of expelling wind and cold, removing damp-heat, relaxing muscles and tendons to promote blood circulation, benefiting QI and nourishing blood, the various symptoms that treatment migraine is caused have significant curative effect, short treating period, instant effect, safe and reliable, without any side effects, and taking convenience, be easy to absorb, with low cost, treating both the principal and secondary aspects of a disease, non-relapse after healing, can be widely used in migrainous clinical treatment.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Treat a preparation method for migrainous Chinese medicine preparation, comprise following processing step:
(1) by Cladonia alpestris (L.) Rabenh., Caulis seu folium chloranthi spicati (Chloranthus spicatus(Thunb.) Mak.), Radix Lagerstroemia indica L., Cortex Moutan, Flos Papaveris rhoeadis, Herba Vaccinii Bracteati, Herba Cynanchi Thesioidis, hang rock wind, Radix Luculiae intermediae and cicada clean, put into container, add the distilled water of 8～10 times of amounts, soaks after 5～6 hours, boil 3～4 hours, extraction; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 DEG C, relative density is 1.10～1.13, for subsequent use;
(2) Radix Luffae is put into pot, intense fire is fried, and puts into container and carry out pulverization process after having fried, and grinds into powder, crosses 200 order fine powders, for subsequent use;
(3) Radix Dendropanacis, Radix et rhizoma smilacinae japonicae and black Rhizoma Ligustici are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
(4) Radix seu Caulis Parthenocissi tricuspidatae and Herba Artemisiae Brachylobae are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(5) above-mentioned steps (1)～(4) prepared thick paste and fine powder are mixed, make capsule, obtain the migrainous Chinese medicine preparation for the treatment of of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, can fully recover 3～4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the migrainous Chinese medicine preparation for the treatment of, select the routine clinical observation of migraineur 186 of making a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups at random, treatment group 93 examples, wherein male's 46 examples, women's 47 examples, 18～50 years old age, 32 years old mean age, the course of disease 1～5 year; Matched group 93 examples, wherein male's 47 examples, women's 46 examples, 19～51 years old age, 35 years old mean age, the course of disease 1～4 year, the course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 5 days, be 1 course for the treatment of, can fully recover 3～4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Matched group is taken ibuprofen modified release capsule, oral, adult, and each 1, each 2 times, clothes after the meal, the course for the treatment of is depending on the state of an illness.
3, efficacy determination:
(1) cure: symptom all disappears, and laboratory inspection is normal.
(2) effective: symptom obviously alleviates, lab testing obviously improves.
(3) effective: symptom alleviates to some extent, and lab testing makes moderate progress.
(4) invalid: by treating rear symptom without improving or increasing the weight of.
4, result:
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, journey, female, 19 years old, people from Xianyang.Patient's paroxysmal right side migraine 2 months, often vexed, dreaminess, lustreless complexion, white and greasy fur is thicker, and matter is light, and thready pulse chi is soft, and blood pressure 145/105mmHg used multiple Drug therapy, poor effect, it is invalid to cure.To our hospital afterwards, take Chinese medicine preparation treatment of the present invention, to take after 1 course for the treatment of, symptom disappears substantially, takes after the 2nd course for the treatment of, and migraine heals entirely, follows up a case by regular visits to, so far not recurrence.
2, the Meng, man, 24 years old, people from west city, Beijing.Patient has a headache 1 year, and two temple pain is felt sick sometimes, and sustainable 1 day of pain connects and eye socket, red tongue, and body is bigger, and tongue is white, stringy pulse; Take the above-mentioned Chinese medicine preparation treatment of the present invention, take after 1 course for the treatment of, when rise morning, still have a headache, tongue body is bigger, and tongue is white, stringy pulse, continue to take after 1 course for the treatment of, do not send out headache, yellow urine, tongue body is bigger, and matter is red, and tongue is white, stringy pulse, continued to take after 1 course for the treatment of, and migraine heals entirely, followed up a case by regular visits to, so far not recurrence.
3, health, female, 30 years old, the large Hongkong people in Tianjin.Patient's paroxysmal right side migraine 2 months, often vexed, dreaminess, white and greasy fur is thicker, lustreless complexion, thready pulse chi is soft, and blood pressure 145/105mmHg used multiple Drug therapy, and curative effect is very poor, fails to respond to any medical treatment.To our hospital afterwards, take Chinese medicine preparation treatment of the present invention, to take after 2 courses for the treatment of, symptom disappears substantially, takes after the 3rd course for the treatment of, and migraine is cured, and follows up a case by regular visits to, not recurrence after 1 year.
4, model, man, 34 years old, people from Yangpu, Shanghai.Patient has a headache 4 years, and left side temple are main, jumping pain, and sleep difference can be brought out, monthly aches 3～4 times, persistence, fever sensation of the face, dark tongue quality, body is large, and tongue is white, stringy pulse.Take after 1 course for the treatment of of Chinese medicine preparation of the present invention, headache is not sent out, time have a fever sensation of the face, sleep also take a favorable turn, dark tongue quality, and tongue is white, stringy pulse, continued to take after 1 course for the treatment of of Chinese medicine preparation of the present invention, and times of headache obviously reduces, lighter, dark tongue quality, body is bigger, tongue is white, and stringy pulse continued to take after 1 course for the treatment of of Chinese medicine preparation of the present invention, headache disappears, and follows up a case by regular visits to, not recurrence after half a year.
5, Qiu, female, 42 years old, Kowloon, Chongqing people from slope.Patient has a headache 3 years, and left side temple are main, jumping pain, and sleep difference can be brought out, monthly aches 2～3 times, persistence, fever sensation of the face, dark tongue quality, body is large, and tongue is white, stringy pulse.Take Chinese medicine preparation of the present invention treatment, take after 1 course for the treatment of, headache is not sent out, time have a fever sensation of the face, sleep also take a favorable turn, dark tongue quality, and tongue is white, stringy pulse, continue to take after 1 course for the treatment of, only show effect 11 middle of the month of having a headache, lighter, dark tongue quality, body is bigger, and tongue is white, and stringy pulse continued to take after 2 courses for the treatment of, headache disappears, time have fever sensation of the face, tongue body is large, matter is red dark, tongue is white, stringy and rolling pulse, and Effect of follow-up visit by telephone after 2 months, headache is again without showing effect.
6, congratulate certain, man, 49 years old, Anshan, liaoning Province people.Patient has a headache 5 years, is twinge, often perspire, and bitter taste, flushing, thirsty.Take after the 1st course for the treatment of, headache alleviates, and perspires few, takes after the 2nd course for the treatment of, and headache, perspiration all alleviate, dark tongue quality, and point is red, and tongue is white, and deep and stringy pulse was taken after the 3rd course for the treatment of, and headache disappears, and follows up a case by regular visits to, so far not recurrence.
Claims (5)
1. the migrainous Chinese medicine preparation for the treatment of, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
38～62 parts of 41～65 parts of Cortex Moutans of 43～67 parts of Radix Lagerstroemia indica L.s of 44～68 portions of Caulis seu folium chloranthi spicati (Chloranthus spicatus(Thunb.) Mak.)s of Cladonia alpestris (L.) Rabenh.
33～57 parts of 35～59 portions of Flos Papaveris rhoeadiss of 35～59 portions of Radix seu Caulis Parthenocissi tricuspidataes of 36～60 parts of Radix Dendropanacis of Radix Luffae
32～56 parts of 32～56 parts of Herba Cynanchi Thesioidis of Herba Vaccinii Bracteati hang 28～52 parts of 30～54 parts of Radix et rhizoma smilacinae japonicaes of rock wind
20～44 parts of 23～47 parts of black Rhizoma Ligusticis of 27～51 parts of cicada of 28～52 parts of Radix Luculiae intermediaes of Herba Artemisiae Brachylobae.
2. one according to claim 1 is treated migrainous Chinese medicine preparation, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
42～58 parts of 45～61 parts of Cortex Moutans of 47～63 parts of Radix Lagerstroemia indica L.s of 48～64 portions of Caulis seu folium chloranthi spicati (Chloranthus spicatus(Thunb.) Mak.)s of Cladonia alpestris (L.) Rabenh.
37～53 parts of 39～55 portions of Flos Papaveris rhoeadiss of 39～55 portions of Radix seu Caulis Parthenocissi tricuspidataes of 40～56 parts of Radix Dendropanacis of Radix Luffae
36～52 parts of 36～52 parts of Herba Cynanchi Thesioidis of Herba Vaccinii Bracteati hang 32～48 parts of 34～50 parts of Radix et rhizoma smilacinae japonicaes of rock wind
24～40 parts of 27～43 parts of black Rhizoma Ligusticis of 31～47 parts of cicada of 32～48 parts of Radix Luculiae intermediaes of Herba Artemisiae Brachylobae.
3. one according to claim 1 is treated migrainous Chinese medicine preparation, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
46～54 parts of 49～57 parts of Cortex Moutans of 51～59 parts of Radix Lagerstroemia indica L.s of 52～60 portions of Caulis seu folium chloranthi spicati (Chloranthus spicatus(Thunb.) Mak.)s of Cladonia alpestris (L.) Rabenh.
41～49 parts of 43～51 portions of Flos Papaveris rhoeadiss of 43～51 portions of Radix seu Caulis Parthenocissi tricuspidataes of 44～52 parts of Radix Dendropanacis of Radix Luffae
40～48 parts of 40～48 parts of Herba Cynanchi Thesioidis of Herba Vaccinii Bracteati hang 36～44 parts of 38～46 parts of Radix et rhizoma smilacinae japonicaes of rock wind
28～36 parts of 31～39 parts of black Rhizoma Ligusticis of 35～43 parts of cicada of 36～44 parts of Radix Luculiae intermediaes of Herba Artemisiae Brachylobae.
4. one according to claim 1 is treated migrainous Chinese medicine preparation, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
50 parts of 53 parts of Cortex Moutans of 55 parts of Radix Lagerstroemia indica L.s of 56 portions of Caulis seu folium chloranthi spicati (Chloranthus spicatus(Thunb.) Mak.)s of Cladonia alpestris (L.) Rabenh.
45 parts of 47 portions of Flos Papaveris rhoeadiss of 47 portions of Radix seu Caulis Parthenocissi tricuspidataes of 48 parts of Radix Dendropanacis of Radix Luffae
44 parts of 44 parts of Herba Cynanchi Thesioidis of Herba Vaccinii Bracteati hang 40 parts of 42 parts of Radix et rhizoma smilacinae japonicaes of rock wind
32 parts of 35 parts of black Rhizoma Ligusticis of 39 parts of cicada of 40 parts of Radix Luculiae intermediaes of Herba Artemisiae Brachylobae.
5. a preparation method for the treatment of migrainous Chinese medicine preparation as described in claim 1～4 any one, is characterized in that: comprise following processing step:
(1) by Cladonia alpestris (L.) Rabenh., Caulis seu folium chloranthi spicati (Chloranthus spicatus(Thunb.) Mak.), Radix Lagerstroemia indica L., Cortex Moutan, Flos Papaveris rhoeadis, Herba Vaccinii Bracteati, Herba Cynanchi Thesioidis, hang rock wind, Radix Luculiae intermediae and cicada clean, put into container, add the distilled water of 8～10 times of amounts, soaks after 5～6 hours, boil 3～4 hours, extraction; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 DEG C, relative density is 1.10～1.13, for subsequent use;
(2) Radix Luffae is put into pot, intense fire is fried, and puts into container and carry out pulverization process after having fried, and grinds into powder, crosses 200 order fine powders, for subsequent use;
(3) Radix Dendropanacis, Radix et rhizoma smilacinae japonicae and black Rhizoma Ligustici are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
(4) Radix seu Caulis Parthenocissi tricuspidatae and Herba Artemisiae Brachylobae are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(5) above-mentioned steps (1)～(4) prepared thick paste and fine powder are mixed, make capsule, obtain the migrainous Chinese medicine preparation for the treatment of of the present invention.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147809A (en) * | 2015-09-18 | 2015-12-16 | 董金兰 | Traditional Chinese medicine composition treating wind-heat upper disturbing type supraorbital neuralgia |
| CN105770360A (en) * | 2016-04-28 | 2016-07-20 | 李秀芬 | Traditional Chinese medicinal preparation for treating cephalagra and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101288724A (en) * | 2008-05-15 | 2008-10-22 | 胡国良 | Chinese medicinal preparation for treating persistent dysentery |
| CN102370814A (en) * | 2010-08-11 | 2012-03-14 | 叶明华 | Traditional Chinese medicine preparation used for treating migraine |
| CN103520555A (en) * | 2013-10-27 | 2014-01-22 | 周文华 | Drug for treatment of migraine |
-
2014
- 2014-04-19 CN CN201410158653.2A patent/CN103893488A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101288724A (en) * | 2008-05-15 | 2008-10-22 | 胡国良 | Chinese medicinal preparation for treating persistent dysentery |
| CN102370814A (en) * | 2010-08-11 | 2012-03-14 | 叶明华 | Traditional Chinese medicine preparation used for treating migraine |
| CN103520555A (en) * | 2013-10-27 | 2014-01-22 | 周文华 | Drug for treatment of migraine |
Non-Patent Citations (1)
| Title |
|---|
| 冀绪等: ""清热祛风活血止痛法治疗偏头痛50例临床研究"", 《河北中医》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147809A (en) * | 2015-09-18 | 2015-12-16 | 董金兰 | Traditional Chinese medicine composition treating wind-heat upper disturbing type supraorbital neuralgia |
| CN105770360A (en) * | 2016-04-28 | 2016-07-20 | 李秀芬 | Traditional Chinese medicinal preparation for treating cephalagra and preparation method thereof |
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