CN103877390A - Traditional-Chinese-medicine preparation for treating rheumatic fever and preparation method thereof - Google Patents
Traditional-Chinese-medicine preparation for treating rheumatic fever and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional-Chinese-medicine preparation for treating rheumatic fever and a preparation method thereof and belongs to the field of traditional Chinese medicines. The traditional-Chinese-medicine preparation comprises the following raw materials constituting effective ingredients: xanthium strumarium, fohum aconiti kusnezoffii, white perilla leaf, herb of Chinese arundina, ardisia crispa, syzygium buxifolium, drymoglossum piloselloides presl, lilium brownii, bellflower, radix angelicae, common ducksmeat herb, ramose scouring rush herb, semen boitae, euonymus macropterus, Chinese parsnip root and Chinese mesona herb. The traditional-Chinese-medicine preparation is suitable in compatibility of selected medicines, conforms to the theory of traditional Chinese medicine and pharmacy and modern medicine and pharmacology, has the effects of clearing heat and removing toxicity, alleviating spasm and pain, dispelling wind and promoting diuresis and activating blood and dredging channels, has an obvious treating effect for treating the rheumatic fever caused by the symptoms such as generalized fatigue, anorexia and dysphoria, is convenient to take, safe and reliable, allows fast effect without toxic and side effects and low in cost, and can treat both symptoms and root causes.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation and preparation method for the treatment of rheumatic fever.
Background technology
Rheumatic fever is the acute of a kind of common outbreak repeatedly or chronic Shen Xing ICT, mainly involves heart, joint, central nervous system, skin and subcutaneous tissue.Clinical manifestation, can be with heating, toxemia, erythra, subcutaneous nodule, chorea etc. taking carditis and arthritis as main.Conventionally comparatively obvious with arthritis when acute attack, but can cause patient death in this stage rheumatic carditis, after acute attack, often leave over the heart damage that weight does not wait, especially the most remarkable with valve pathological changes, form chronic rheumatic heart disease or rheumatic valvular disease, the joint damage causing due to rheumatic fever can recover voluntarily, but the infringement of heart is irreversible, therefore there is people also to describe rheumatic fever with " lick joint, resolutely sting heart ".
The most patient's premorbids of rheumatic fever first have the upper respiratory tract infection such as pharyngitis or tonsillitis history for 1～5 week, and when onset, the whole body is tired, loss of appetite, agitation.Rheumatic fever is migratory polyarthritis, and normal symmetry is involved the large joint such as knee joint, ankle, shoulder, wrist, elbow, hip; Part is, and inflammation red, swollen, hot, pain shows, but does not suppurate.Part patient falls ill in several joints simultaneously, hands, the little joint of foot or joint of vertebral column etc. also can involve, conventionally outbreak in month after streptococcal infection, antistreptococcal antibody titer often can increase, and after acute inflammation subsides, function of joint is recovered completely, do not leave over ankylosis and deformity, but Chang Fanfu outbreak, typical person is in recent years rare, the degree of local joint inflammation with have or not carditis or cardiac valve pathological changes without obvious relation.
The therapeutic purposes of rheumatic fever should comprise following 4 aspects: 1. remove streptococcal infection focus; 2. whether Early observation carditis exists and is processed; 3. control congestive heart failure; 4. alleviate joint and other symptoms.Due to the variation of clinical disease type, the order of severity of the state of an illness has larger difference, therefore should carry out individual treatment in treatment.
Rheumatic fever is apt to occur in very cold and humid area, invades child and teenager more, and Winter-Spring sickness rate cold season is higher.The curative effect of medication of the flourishing rheumatic fever for the treatment of pathogenic heat of selling is in the market not remarkable, cures the symptoms, not the disease, and curative effect is slow, and relapse rate is high.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of rheumatic fever; The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of heat-clearing and toxic substances removing, spasmolytic pain relieving, expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, the rheumatic fever that the symptoms such as the whole body is tired to having treated, loss of appetite, agitation cause has significant therapeutic effect, and taking convenience is safe and reliable, quick result, have no side effect, with low cost, can reach the object for the treatment of both the principal and secondary aspects of a disease.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for rheumatic fever, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
18～42 parts of 21～45 parts of Herba Arundinae Chinensiss of 23～47 parts of Folium Perillae Frutescentiss of 24～48 portions of Folium Aconiti Kusnezoffii of Herba Xanthii
13～37 parts of 15～39 portions of Bulbus Liliies of 15～39 parts of Drymoglossum Herba Drymoglossis of 16～41 portions of Radix Syzygii Buxifoliis of Radix Ardisiae Crispae
9～33 parts of 10～34 parts of Herba equiseti ramosissimis of 12～36 portions of Herba Spirodelaes of 12～36 parts of Radixs Angelicae Dahuricae of gristle wind
3～27 parts of 6～30 parts of Herba mesonae chinensiss of 8～32 parts of Radix Saposhnikoviaes of 9～33 parts of Cortex Euonymi phellomaniss of Semen Platycladi.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
22～39 parts of 25～41 parts of Herba Arundinae Chinensiss of 27～43 parts of Folium Perillae Frutescentiss of 28～44 portions of Folium Aconiti Kusnezoffii of Herba Xanthii
17～33 parts of 19～35 portions of Bulbus Liliies of 19～35 parts of Drymoglossum Herba Drymoglossis of 20～37 portions of Radix Syzygii Buxifoliis of Radix Ardisiae Crispae
13～29 parts of 13～30 parts of Herba equiseti ramosissimis of 16～32 portions of Herba Spirodelaes of 16～32 parts of Radixs Angelicae Dahuricae of gristle wind
7～23 parts of 10～26 parts of Herba mesonae chinensiss of 12～28 parts of Radix Saposhnikoviaes of 13～29 parts of Cortex Euonymi phellomaniss of Semen Platycladi.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
26～34 parts of 29～37 parts of Herba Arundinae Chinensiss of 31～39 parts of Folium Perillae Frutescentiss of 32～40 portions of Folium Aconiti Kusnezoffii of Herba Xanthii
21～29 parts of 23～31 portions of Bulbus Liliies of 23～31 parts of Drymoglossum Herba Drymoglossis of 24～32 portions of Radix Syzygii Buxifoliis of Radix Ardisiae Crispae
17～25 parts of 18～26 parts of Herba equiseti ramosissimis of 20～28 portions of Herba Spirodelaes of 20～28 parts of Radixs Angelicae Dahuricae of gristle wind
11～19 parts of 14～22 parts of Herba mesonae chinensiss of 16～24 parts of Radix Saposhnikoviaes of 17～25 parts of Cortex Euonymi phellomaniss of Semen Platycladi.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
30 parts of 33 parts of Herba Arundinae Chinensiss of 35 parts of Folium Perillae Frutescentiss of 36 portions of Folium Aconiti Kusnezoffii of Herba Xanthii
25 parts of 27 portions of Bulbus Liliies of 27 parts of Drymoglossum Herba Drymoglossis of 28 portions of Radix Syzygii Buxifoliis of Radix Ardisiae Crispae
21 parts of 22 parts of Herba equiseti ramosissimis of 24 portions of Herba Spirodelaes of 24 parts of Radixs Angelicae Dahuricae of gristle wind
15 parts of 18 parts of Herba mesonae chinensiss of 20 parts of Radix Saposhnikoviaes of 21 parts of Cortex Euonymi phellomaniss of Semen Platycladi.
Treat a preparation method for the Chinese medicine preparation of rheumatic fever, comprise following processing step:
(1) Herba Xanthii, Folium Perillae Frutescentis, Herba Arundinae Chinensis, Radix Ardisiae Crispae, Radix Syzygii Buxifolii, Drymoglossum Herba Drymoglossi, Bulbus Lilii, gristle wind, Semen Platycladi, Radix Saposhnikoviae and Herba mesonae chinensis are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, the thick paste that at 60 DEG C of simmer down tos, relative density is 1.10～1.13, for subsequent use;
(2) Folium Aconiti Kusnezoffii and the Radix Angelicae Dahuricae are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(3) Herba Spirodelae and Herba equiseti ramosissimi are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Cortex Euonymi phellomanis is cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating and refluxing extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Xanthii: toil, is slightly cold; Return lung meridian.Arthralgia chiefly caused by damp pathogen contracture, loose wind dehumidifying, understand things pain-stopping.Cure mainly flu, wind syndrome of head, dizziness, nasal sinusitis, conjunctival congestion, corneal nebula, pathogenic wind-warm arthralgia pain, contracture numbness, wind leprosy, furuncle, scabies, skin pruritus, hemorrhoid, dysentery, wind and heat eliminating, removing toxic substances parasite killing." herbal classic " carries: " spasm of the limbs pain, dislikes the dead mark of meat for the cold pain of main air head, rheumatism general arthralgia.”
Folium Aconiti Kusnezoffii: acrid in the mouth, puckery, property is flat, slightly poisonous.Heat clearing away, removing toxic substances, pain relieving.For calentura heating, the stomachache of having loose bowels, headache, toothache.
Folium Perillae Frutescentis: acrid in the mouth, warm in nature; Start with, meridian of Foot-TAI YIN.The cold expelling that induces sweat, regulates the flow of vital energy and helps digestion.The wind and cold that cures cold, fever with aversion to cold, cough, asthma, food stagnation, vomits and diarrhoea, cold-dysentery." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " cure the wound cold heating, lossless, headache, all wind and cold expectorant gush and tie, cramp caused by acute vomiting and diarrhea, cough is spat, children's's wind disease.Analgesic therapy, Zhichuan.”
Herba Arundinae Chinensis: bitter in the mouth, property is flat.Heat-clearing and toxic substances removing, expelling wind and removing dampness.Cure mainly pyretic stranguria, jaundice, edema, beriberi edema, hernia stomachache, rheumatic arthralgia, venom, sore and toxic, traumatic injury." choosing of Simao, Yunnan Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, wind-damp dispelling, antiinflammatory, diuresis.Treating rheumatic lumbago and skelalgia, stomachache, urinary tract infection, beriberi edema, alimentary toxicosis.”
Radix Ardisiae Crispae: bitter in the mouth, pungent, cool in nature.Heat clearing away, eliminates the phlegm, dampness removing.Control laryngopharynx swelling and pain, pneumonopathy cough, coughs up phlegm not smooth, jaundice due to damp-heat, oedema due to nephritis, dysentery, nebulousurine, rheumatic ostalgia, toothache, painful and swollen testis." Fujian Chinese herbal medicine " carries: " clearing away heat-damp and promoting diuresis.Control jaundice due to damp-heat, dysentery, nebulousurine, swollen testis pendant pain, tinea alba, scabies.”
Radix Syzygii Buxifolii: sweet in the mouth, micro-hardship, pungent, property is flat; Return kidney,spleen,liver warp.Invigorating spleen to remove dampness, relievings asthma, dissipating blood stasis for subsidence of swelling.Main breathing with cough, edema, stranguria with turbid discharge, lithangiuria, dysentery, hepatitis, uterine prolapse, rheumatalgia, hernia, orchitis, hemorrhoid, carbuncle, burn due to hot liquid or fire, treating swelling and pain by traumatic injury." Guangxi medicine is planted register " carries: " control burn, traumatic injury, controls finger skin ulcer.”
Drymoglossum Herba Drymoglossi: sweet in the mouth, light, slightly cool in nature; Return liver, lung meridian.Clearing away heat-damp and promoting diuresis, removing toxic substances parasite killing.The subcutaneous ulcer of harnessing the Yellow River, rheumatalgia, parotitis, tuberculous lymphadenitis, mange, traumatic injury.Guangzhou air force " conventional Chinese herbal medicine handbook " carries: " eliminating inflammation and expelling toxin, dispelling wind stopping cough.The subcutaneous ulcer of harnessing the Yellow River, tuberculous lymphadenitis, parotitis, cough hemoptysis, rheumatic ostalgia, breast carcinoma, constipation due to dry stool.”
Bulbus Lilii: sweet in the mouth, micro-hardship, property is flat; Enter lung, the heart, gallbladder three warps.Nourishing the lung to arrest cough, clearing away heart-fire for tranquillization.Cure mainly lung expense chronic cough, cough and spit expectorant blood, after calentura, waste heat comes clearly, fidgets due to deficiency palpitation with fear, staring spells, beriberi edema." property of medicine opinion " carries: " except spasm in the epigastrium, full, bitterly, control beriberi, heat syndrome cough is contrary.”
Gristle wind: sweet in the mouth, micro-puckery, property is flat; Return liver, kidney channel.Expelling wind and removing dampness, eliminating stasis to stop pain.Main air pain of dampness syndrome, lumbago, puerperal abdonimal pain, traumatic injury.
The Radix Angelicae Dahuricae, acrid in the mouth, warm in nature; Attach to the lung and stomach meridians.Expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping.Be widely used in the treatment of the diseases such as soft tissue contusion, hyperosteogeny, muscular strain, rheumatic myositis, fracture, costal chondritis, scapulohumeral periarthritis, intercostal neuralgia.The Radix Angelicae Dahuricae all has inhibitory action to escherichia coli, dysentery bacterium, Bacillus proteus, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus, vibrio cholera, Bacillus tuberculosis etc.
Herba Spirodelae: acrid in the mouth, cold in nature; Return lung, urinary bladder channel.Relieving the exterior syndrome by diaphoresis, rash is antipruritic, inducing diuresis to remove edema, heat-clearing and toxic substances removing.Main air hotlist disease, measles without adequate eruption, urticaria pruritus, edema, the difficulty in urination, skin ulcer tinea, erysipelas, scalds." detailed outline " carries: " the wet paralysis of main air, beriberi, beats and flutters damage, conjunctivitis, aphtha of the mouth and tongue, spits blood, epistaxis, paralysed wind, erysipelas.”
Herba equiseti ramosissimi: sweet in the mouth, hardship, property is put down, is slightly cold, nontoxic; GUIXIN, liver, stomach, urinary bladder channel.Liver heat removing and eyesight improving, hemostasis, inducing diuresis for treating stranguria syndrome.Main anemopyretic cold, cough, conjunctival congestion and swelling pain, nebula, epistaxis, hematuria, discharging fresh blood stool, stranguria, jaundice, leukorrhagia, fracture." Traditional Chinese Medicine in Sichuan will " carries: " clearing away heart-fire, removes hectic fever, scattered clouds nebula.Control epidemic hemorrhagic conjunctivitis, puckery pain, overflow tear and conjunctival congestion and swelling pain, and treat nose bleeding.”
Semen Platycladi: sweet in the mouth, property is flat; GUIXIN, kidney, large intestine channel.Tranquilizing by nourishing the heart, hidroschesis intestine moistening.For fidgets due to deficiency insomnia, severe palpitation, night sweat due to yin deficiency, dryness of the intestine constipation." detailed outline " carries: " gas that nourishes heart, profit kidney is dry, and Fructus Alpiniae Oxyphyllae is allayed excitement; Burn drop and control scabies.”
Cortex Euonymi phellomanis: cold in nature, bitter in the mouth; Enter liver, lung two warps.The removing blood stasis tire that falls, regulating menstruation Radix Dipsaci.Control puerperal abdonimal pain, metrorrhagia hematochezia, rheumatalgia.
Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature; Return bladder, lung, spleen, Liver Channel.Expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic.Cure mainly affection of exogenous wind-cold, headache general pain, rheumatic arthralgia, joint is ached, stomachache is had loose bowels, discharging fresh blood stool, tetanus, rubella pruritus, skin infection from the beginning of." Changsha medicine solution " carries: " network of passing through, by wet excessive, gets round by bribery, the pain that relieves the pain, and relaxing muscles and tendons arteries and veins, stretches anxious twinly, and the podomere of living, plays paralysis, holds back spontaneous perspiration, night sweat, breaks, metrorrhagia.”
Herba mesonae chinensis: antipyretic diuretic.Cure mainly heatstroke, pyretic toxicity, quench one's thirst, hypertension, nephropathy, diabetes, pain of joint muscle, gonorrhea etc.Modern medicine study confirmation, in Herba mesonae chinensis ingredient, Flavonoid substances has the effect that suppresses cancer cell growth, reduces blood pressure; Polysaccharide has enhancing and improves human body immune function effect; Essence have effect of calmness, refrigerant, removing toxic substances, diuretic; Trace element has free radical formation, defying age, the anticancer effect of suppressing; Vitamin can regulate and strengthen physiological function etc.
The present invention compared with prior art, has following beneficial effect:
The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of heat-clearing and toxic substances removing, spasmolytic pain relieving, expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, the rheumatic fever that the symptoms such as the whole body is tired to having treated, loss of appetite, agitation cause has significant therapeutic effect, and taking convenience is safe and reliable, quick result, have no side effect, with low cost, can reach the object for the treatment of both the principal and secondary aspects of a disease.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Herba Xanthii 44g Folium Aconiti Kusnezoffii 43g Folium Perillae Frutescentis 41g Herba Arundinae Chinensis 39g
Radix Ardisiae Crispae 37g Radix Syzygii Buxifolii 35g Drymoglossum Herba Drymoglossi 35g Bulbus Lilii 33g
Gristle wind 32g Radix Angelicae Dahuricae 32g Herba Spirodelae 30g Herba equiseti ramosissimi 29g
Semen Platycladi 29g Cortex Euonymi phellomanis 28g Radix Saposhnikoviae 26g Herba mesonae chinensis 23g.
Treat a preparation method for the Chinese medicine preparation of rheumatic fever, comprise following processing step:
(1) Herba Xanthii, Folium Perillae Frutescentis, Herba Arundinae Chinensis, Radix Ardisiae Crispae, Radix Syzygii Buxifolii, Drymoglossum Herba Drymoglossi, Bulbus Lilii, gristle wind, Semen Platycladi, Radix Saposhnikoviae and Herba mesonae chinensis are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, the thick paste that at 60 DEG C of simmer down tos, relative density is 1.10～1.13, for subsequent use;
(2) Folium Aconiti Kusnezoffii and the Radix Angelicae Dahuricae are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(3) Herba Spirodelae and Herba equiseti ramosissimi are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Cortex Euonymi phellomanis is cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating and refluxing extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 6 days, be 1 course for the treatment of, can fully recover 3～4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Herba Xanthii 40g Folium Aconiti Kusnezoffii 39g Folium Perillae Frutescentis 37g Herba Arundinae Chinensis 34g
Radix Ardisiae Crispae 32g Radix Syzygii Buxifolii 31g Drymoglossum Herba Drymoglossi 31g Bulbus Lilii 29g
Gristle wind 28g Radix Angelicae Dahuricae 28g Herba Spirodelae 26g Herba equiseti ramosissimi 25g
Semen Platycladi 25g Cortex Euonymi phellomanis 24g Radix Saposhnikoviae 22g Herba mesonae chinensis 19g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Herba Xanthii 36g Folium Aconiti Kusnezoffii 35g Folium Perillae Frutescentis 33g Herba Arundinae Chinensis 30g
Radix Ardisiae Crispae 28g Radix Syzygii Buxifolii 27g Drymoglossum Herba Drymoglossi 27g Bulbus Lilii 25g
Gristle wind 24g Radix Angelicae Dahuricae 24g Herba Spirodelae 22g Herba equiseti ramosissimi 21g
Semen Platycladi 21g Cortex Euonymi phellomanis 20g Radix Saposhnikoviae 18g Herba mesonae chinensis 15g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Herba Xanthii 32g Folium Aconiti Kusnezoffii 31g Folium Perillae Frutescentis 29g Herba Arundinae Chinensis 26g
Radix Ardisiae Crispae 24g Radix Syzygii Buxifolii 23g Drymoglossum Herba Drymoglossi 23g Bulbus Lilii 21g
Gristle wind 20g Radix Angelicae Dahuricae 20g Herba Spirodelae 18g Herba equiseti ramosissimi 17g
Semen Platycladi 17g Cortex Euonymi phellomanis 16g Radix Saposhnikoviae 14g Herba mesonae chinensis 11g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Herba Xanthii 28g Folium Aconiti Kusnezoffii 27g Folium Perillae Frutescentis 25g Herba Arundinae Chinensis 22g
Radix Ardisiae Crispae 20g Radix Syzygii Buxifolii 19g Drymoglossum Herba Drymoglossi 19g Bulbus Lilii 17g
Gristle wind 16g Radix Angelicae Dahuricae 16g Herba Spirodelae 13g Herba equiseti ramosissimi 13g
Semen Platycladi 13g Cortex Euonymi phellomanis 12g Radix Saposhnikoviae 10g Herba mesonae chinensis 7g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of rheumatic fever, select the routine clinical observation of rheumatic fever patient 326 of making a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups at random, treatment group 163 examples, wherein male's 83 examples, women's 80 examples, 5～51 years old age, 35.6 years old mean age, the course of disease 3 months～2 years; Matched group 163 examples, wherein male's 81 examples, women's 82 examples, 6～50 years old age, 33.2 years old mean age, the course of disease 2 months～2 years.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 6 days, be 1 course for the treatment of, take continuously 3～4 courses for the treatment of, the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Matched group is taken oxacillin sodium sheet, oral, and each 2～4, every day 4～5 times, the course for the treatment of is depending on the state of an illness.
3, efficacy determination:
(1) cure: above-mentioned symptom all disappears.
(2) effective: above-mentioned symptom obviously alleviates.
(3) effective: above-mentioned symptom alleviates to some extent.
(4) invalid: by treating rear above-mentioned symptom without alleviating or increasing the weight of.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 79 examples, effective 46 examples, effective 35 examples, invalid 3 examples, cure rate 48.5%, total effective rate 98.2%.
In matched group, cure 39 examples, effective 26 examples, effective 18 examples, invalid 80 examples, cure rate 23.9%, total effective rate 50.9%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, Yao, female, 30 years old, people in Chongqing.Patient's rheumatic fever causes erythema iris existing 1 year, uses multiple Drug therapy, and always outbreak was repeatedly taken after 1 course for the treatment of of Chinese medicine preparation of the present invention, and symptom turns for the better by and large, and continues to take after 2 courses for the treatment of, and symptom disappears completely, follows up a case by regular visits to so far without recurring.
2, Liao, man, 35 years old, people from Dalian.The female toe congestion and swelling pain of patient's left foot three days, is diagnosed as rheumatic fever.As antiinflammatory such as penicillins, take ibuprofen with western medicine and medical practitioners orally, ibuprofen pain relieving effect is micro-.Doctor advised was taken after 1 course for the treatment of of Chinese medicine preparation of the present invention, and the female toe congestion and swelling pain of left foot symptom obviously alleviates, and continues to take after 2 courses for the treatment of, and transference cure, follows up a case by regular visits to after 1 year without recurrence.
3, Zou, female, 20 years old, people from Changchun, Jilin.Patient is because of heating general pain, the breast side of body is unfavorable, dare not breathe, and removes hospital admission, be diagnosed as rheumatic fever, take subsequently Chinese medicine preparation treatment of the present invention, take 1 course for the treatment of, above symptom is clearly better, continue to take after 1 course for the treatment of of Chinese medicine preparation of the present invention, above transference cure, physical recovery is normal, after half a year, does not follow up a case by regular visits to and recurs.
4, the summer, man, 17 years old, people from Tangshan.Patient main suit has upper respiratory tract infection history, and migration, polyarthritis, appear being in heating, pharyngalgia, and taking ankle, elbow joint as main, that ankle joint has is red, swollen, hot, bitterly, and postemphasis, gives penicillin drop 1 week poor effect in local commune hospital.After take Chinese medicine preparation of the present invention treatment, take 1 course for the treatment of, symptom is obviously alleviated, continue to take after 2 courses for the treatment of of Chinese medicine preparation of the present invention, transference cure, physical recovery is normal, after 2 years, does not follow up a case by regular visits to and recurs.
5, Pan, female, 46 years old, Shandong Dongying people.Patient the 3rd time recurrence rheumatic fever is all by catching a cold or throat inflammation causes disease, through friend recommendation at every turn, to our hospital, to take after 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom is clearly better, take after 2 courses for the treatment of of Chinese medicine preparation of the present invention, recovery from illness, follows up a case by regular visits to so far not recurrence.
6, Cui, man, 49 years old, Zhenjiang, Jiangsu people.Patient had pharyngalgia, heating before 10 days, go out-patient treatment, gave multi-medicament treatment rear transference cure, occurred in the recent period joint migration pain, and ankle joint has subcutaneous nodule, erythema iris around.To our hospital upon somebody's introduction, to take after 1 course for the treatment of of Chinese medicine preparation of the present invention, above-mentioned symptom is obviously alleviated, and continues to take after 2 courses for the treatment of of Chinese medicine preparation of the present invention, and above-mentioned symptom disappears completely, after half a year, does not follow up a case by regular visits to and does not recur.
Claims (5)
1. a Chinese medicine preparation for the treatment of rheumatic fever, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
18～42 parts of 21～45 parts of Herba Arundinae Chinensiss of 23～47 parts of Folium Perillae Frutescentiss of 24～48 portions of Folium Aconiti Kusnezoffii of Herba Xanthii
13～37 parts of 15～39 portions of Bulbus Liliies of 15～39 parts of Drymoglossum Herba Drymoglossis of 16～41 portions of Radix Syzygii Buxifoliis of Radix Ardisiae Crispae
9～33 parts of 10～34 parts of Herba equiseti ramosissimis of 12～36 portions of Herba Spirodelaes of 12～36 parts of Radixs Angelicae Dahuricae of gristle wind
3～27 parts of 6～30 parts of Herba mesonae chinensiss of 8～32 parts of Radix Saposhnikoviaes of 9～33 parts of Cortex Euonymi phellomaniss of Semen Platycladi.
2. a kind of Chinese medicine preparation for the treatment of rheumatic fever according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
22～39 parts of 25～41 parts of Herba Arundinae Chinensiss of 27～43 parts of Folium Perillae Frutescentiss of 28～44 portions of Folium Aconiti Kusnezoffii of Herba Xanthii
17～33 parts of 19～35 portions of Bulbus Liliies of 19～35 parts of Drymoglossum Herba Drymoglossis of 20～37 portions of Radix Syzygii Buxifoliis of Radix Ardisiae Crispae
13～29 parts of 13～30 parts of Herba equiseti ramosissimis of 16～32 portions of Herba Spirodelaes of 16～32 parts of Radixs Angelicae Dahuricae of gristle wind
7～23 parts of 10～26 parts of Herba mesonae chinensiss of 12～28 parts of Radix Saposhnikoviaes of 13～29 parts of Cortex Euonymi phellomaniss of Semen Platycladi.
3. a kind of Chinese medicine preparation for the treatment of rheumatic fever according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
26～34 parts of 29～37 parts of Herba Arundinae Chinensiss of 31～39 parts of Folium Perillae Frutescentiss of 32～40 portions of Folium Aconiti Kusnezoffii of Herba Xanthii
21～29 parts of 23～31 portions of Bulbus Liliies of 23～31 parts of Drymoglossum Herba Drymoglossis of 24～32 portions of Radix Syzygii Buxifoliis of Radix Ardisiae Crispae
17～25 parts of 18～26 parts of Herba equiseti ramosissimis of 20～28 portions of Herba Spirodelaes of 20～28 parts of Radixs Angelicae Dahuricae of gristle wind
11～19 parts of 14～22 parts of Herba mesonae chinensiss of 16～24 parts of Radix Saposhnikoviaes of 17～25 parts of Cortex Euonymi phellomaniss of Semen Platycladi.
4. a kind of Chinese medicine preparation for the treatment of rheumatic fever according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
30 parts of 33 parts of Herba Arundinae Chinensiss of 35 parts of Folium Perillae Frutescentiss of 36 portions of Folium Aconiti Kusnezoffii of Herba Xanthii
25 parts of 27 portions of Bulbus Liliies of 27 parts of Drymoglossum Herba Drymoglossis of 28 portions of Radix Syzygii Buxifoliis of Radix Ardisiae Crispae
21 parts of 22 parts of Herba equiseti ramosissimis of 24 portions of Herba Spirodelaes of 24 parts of Radixs Angelicae Dahuricae of gristle wind
15 parts of 18 parts of Herba mesonae chinensiss of 20 parts of Radix Saposhnikoviaes of 21 parts of Cortex Euonymi phellomaniss of Semen Platycladi.
5. a preparation method for the treatment of the Chinese medicine preparation of rheumatic fever as described in claim 1～4 any one, is characterized in that: comprise following processing step:
(1) Herba Xanthii, Folium Perillae Frutescentis, Herba Arundinae Chinensis, Radix Ardisiae Crispae, Radix Syzygii Buxifolii, Drymoglossum Herba Drymoglossi, Bulbus Lilii, gristle wind, Semen Platycladi, Radix Saposhnikoviae and Herba mesonae chinensis are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, the thick paste that at 60 DEG C of simmer down tos, relative density is 1.10～1.13, for subsequent use;
(2) Folium Aconiti Kusnezoffii and the Radix Angelicae Dahuricae are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(3) Herba Spirodelae and Herba equiseti ramosissimi are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) Cortex Euonymi phellomanis is cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating and refluxing extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
(5) above-mentioned steps (1)～(4) prepared thick paste, fine powder and juice are mixed, make capsule, obtain the Chinese medicine preparation for the treatment of rheumatic fever of the present invention.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104644868A (en) * | 2015-03-23 | 2015-05-27 | 曹燕欣 | Traditional Chinese medicine composition for treating arthritis caused by rheumatic fever and preparation method of traditional Chinese medicine composition |
| CN105753648A (en) * | 2016-03-03 | 2016-07-13 | 陈爱华 | Method for extracting borneol from camphorwood branches and leaves |
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| CN102038872A (en) * | 2009-10-15 | 2011-05-04 | 徐连群 | Medicine for treating rheumatic fever |
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| CN103006770A (en) * | 2012-12-25 | 2013-04-03 | 张爱东 | Chinese medicinal composition for treating rheumatism and rheumatoid |
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| CN102038872A (en) * | 2009-10-15 | 2011-05-04 | 徐连群 | Medicine for treating rheumatic fever |
| CN102872387A (en) * | 2012-10-11 | 2013-01-16 | 王慧艳 | Traditional Chinese medicine composition for treating arthralgia caused by wind-damp-heat pathogens |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104644868A (en) * | 2015-03-23 | 2015-05-27 | 曹燕欣 | Traditional Chinese medicine composition for treating arthritis caused by rheumatic fever and preparation method of traditional Chinese medicine composition |
| CN105753648A (en) * | 2016-03-03 | 2016-07-13 | 陈爱华 | Method for extracting borneol from camphorwood branches and leaves |
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Application publication date: 20140625 |