CN104258147A - Traditional Chinese medicine preparation for treating breast liposarcoma and preparation method of traditional Chinese medicine preparation - Google Patents

Traditional Chinese medicine preparation for treating breast liposarcoma and preparation method of traditional Chinese medicine preparation Download PDF

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CN104258147A
CN104258147A CN201410521287.2A CN201410521287A CN104258147A CN 104258147 A CN104258147 A CN 104258147A CN 201410521287 A CN201410521287 A CN 201410521287A CN 104258147 A CN104258147 A CN 104258147A
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牛艳红
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牛艳红
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/09Lichens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses a traditional Chinese medicine preparation for treating breast liposarcoma and a preparation method of the traditional Chinese medicine preparation, belonging to the field of traditional Chinese medicines. The traditional Chinese medicine preparation is prepared from the following raw materials including polygonum runcinatum, ficus lyrata, youngia japonica, mirabilite, fermented glutinous rice, acorn, sri lanka pouzolzia herb, symplocos paniculata, hispid arthraxon, selaginella doederleinii hieron, drymoglossum piloselloides presl, nidus vespae, usnea, tangerine seed, persicaria perfoliata and vitis bryoniifolia. According to the traditional Chinese medicine preparation disclosed by the invention, the selected medicinal materials are in suitable compatibility and combined to exert the efficacy of invigorating qi, strengthening superficies, relieving liver, smoothing qi, invigorating blood circulation, removing stasis, diminishing inflammation, relieving pains and the like, and the traditional Chinese medicine preparation has the advantages of definite curative effect, fast effect, high cure rate, no toxic and side effects, safety, reliability, convenience in use, low cost and the like for treating the breast liposarcoma, is capable of avoiding pains brought by surgical treatment to a human and can be widely used for clinic treatment of the breast liposarcoma.

Description

A kind of Chinese medicine preparation and preparation method being used for the treatment of mammary fat sarcoma
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation and the preparation method that are used for the treatment of mammary fat sarcoma.
Background technology
Liposarcoma is modal malignant tumor in soft tissue.In the malignant tumor that the circumvascular inmature mesenchymal cell of mammary gland is formed to Adipocyte Differentiation, be called mammary fat sarcoma.According to statistics, sickness rate accounts for the 7-10% of the various malignant tumor of whole body, is that one has a strong impact on the even life-threatening disease of women's physical and mental health.
The cardinal symptom of mammary fat sarcoma has lactiferous ducts obstruction, hypermastia, lump in breast, elderly men breast Silent Neuritis lump, mammary gland dull pain, distending pain of the breast, breast hanging down, huge breast etc.
The cause of disease of mammary fat sarcoma is also completely not clear and definite, but the factor such as bearing status, oral contraceptive, inherited genetic factors, ionizing radiation, unsound dietary habit has been identified relevant with mammary fat sarcoma.The factors such as especially long-term dietary structure, living habit cause the excessive acidify of body constitution, and the function of human body integral declines, and causes liver of suffering from a deficiency of the kidney also empty, and then causes part of the body cavity above the diaphragm housing the heart and lungs metabolic cycles slack-off, easily cause thyroid disease and endocrine disturbance, immunologic function degression.
At present, the treatment of mammary fat sarcoma with operative treatment, radiotherapy and auxiliary Drug therapy for Main Means, and operative treatment can destroy the mammary contour of patient, not only large to patient body wound, also affect emotion and the life of patient, easy initiation complication, and the medical expense of costliness significantly increases the burden of patient.
Chinese medicine is the same with food is derive from the mineral of the Nature, plant, animal drugs, and do not have toxic and side effects, Chinese medicine does not have Drug resistance, can continue to use until radical curing of disease.Therefore we are badly in need of developing a kind of Chinese medicine to alleviate the misery of patient.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and the preparation method that are used for the treatment of mammary fat sarcoma; Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, all medicines are harmonious and have invigorating QI to consolidate the body surface resistance, the effects such as depressed liver-energy dispersing and QI regulating, blood circulation promoting and dispersing pathogen accumulation, anti-inflammatory analgetic, for treatment mammary fat sarcoma have determined curative effect, instant effect, cure rate high, have no side effect, safe and reliable, easy to use, low cost and other advantages, avoid the misery that operative treatment brings to people, the clinical treatment of mammary fat sarcoma can be widely used in.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Be used for the treatment of a Chinese medicine preparation for mammary fat sarcoma, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Be used for the treatment of a preparation method for the Chinese medicine preparation of mammary fat sarcoma, comprise following processing step:
(1) by Herba Polygoni Runcinati, Herba youngiae japonicae with Caulis et folium vitis thunbergii puts into container, immerse 10 times amount volumetric concentration 70% alcohol solution dipping 4 hours, heating extraction, filter, after leaving standstill, reclaiming ethanol and being concentrated into 60 DEG C of relative densities is that the thick paste of 1.12-1.15 is for subsequent use;
(2) container is put in Radix fici panduratae, fermented glutinous rice, Fructus Querci acutissimae, Herba Pouzolziae Zeylanicae, Symplocoris Paniculatae, Herba Arthraxonis Hispidi, Herba Selaginellae Doederleinii, Drymoglossum Herba Drymoglossi, Usnea, Semen Citri Reticulatae and Herba Polygoni Perfoliati mixing, add the distilled water of 4 times amount, boil and extract 3 times, merge extractive liquid, filter, reserved filtrate is for subsequent use;
(3) Natrii Sulfas is put into container, smash to pieces and grind into powder, cross 100 order fine powders, for subsequent use;
(4) Nidus Vespae is cleaned, steam thoroughly, be cut into small pieces, fry to surperficial micro-yellow, take out, after cooling, smash to pieces and grind into powder, cross 120 order fine powders, for subsequent use;
(5) filtrate obtained to thick paste obtained for step (1), step (2) and step (3) and the obtained fine powder of step (4) are mixed, make tablet, be the Chinese medicine preparation being used for the treatment of mammary fat sarcoma of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Polygoni Runcinati: sour in the mouth, hardship, micro-pungent, cold in nature.Heat-clearing and toxic substances removing, promoting blood circulation and detumescence.Control dysentery, leucorrhea, heat in blood is had a headache, metrorrhagia, amenorrhea, acute mastitis furuncle, traumatic injury." the practical Chinese herbal medicine in Guangxi newly selects " carries: " subduing swelling and detoxicating.Control venom, carbuncle furuncle, innominate toxic swelling, mastitis.”
Radix fici panduratae: sweet in the mouth, micro-pungent, property is put down.Expelling wind and removing dampness, removing toxic substances and promoting subsidence of swelling, promoting blood circulation to restore menstrual flow.Main air pain of dampness syndrome, yellow cellulitis, malaria, pertussis, galactostasis, acute mastitis, dysmenorrhea, amenorrhea, carbuncle furuncle and phyma pain, traumatic injury, venom." Jiangxi traditional herbal medicine proved recipe " carries: " dispel the wind, dry, removing toxic substances.Treat malaria, promoting lactation.”
Herba youngiae japonicae: sweet in the mouth, micro-hardship, cool in nature.Heat-clearing and toxic substances removing, inducing diuresis to remove edema.Main flu, pharyngalgia, eye conjunctivitis, acute mastitis, furuncle toxic swelling, venom, dysentery, cirrhotic ascites, acute nephritis, stranguria with turbid discharge, hematuria, leucorrhea, rheumatic arthritis, traumatic injury." the common identification obscuring Chinese herbal medicine " carries: " anti-inflammation.Control furuncle, mastitis, tonsillitis, urinary tract infection, leucorrhea, conjunctivitis, rheumatic arthritis.”
Natrii Sulfas: salty in the mouth, hardship, cold in nature; Return stomach, large intestine channel.Purging heat to relax the bowels, moistening for dryness and softening hard mass, detumescence of relieving inflammation or internal heat.For excess-heat constipation, constipation due to dry stool, stagnant stomachache, acute appendicitis swells and ache; External treatment acute mastitis, swelling and pain of hemorrhoid." book on Chinese herbal medicine is new again " carries: " three burnt the intestines and stomach are damp and hot, push away Chen Zhixin, and typhoid fever fulminant dysentery gathers knot addiction, retention of phlegm stranguria with urinary obstruction, and scrofula skin ulcer swells, and conjunctival congestion is hidden from view, induced abortion of stimulating the menstrual flow." modern medicine study confirmation, Natrii Sulfas can treat mastitis.
Fermented glutinous rice: sweet in the mouth, pungent, warm in nature; Return lung, spleen, stomach warp.QI invigorating, promotes the production of body fluid, and invigorates blood circulation.Main varioliform exanthema can not sent out thoroughly, and acute mastitis swells and ache, headache wind syndrome of head." detailed outline is picked up any lost article from the road " carries: " vaccine lymph sent out by adjuvant drug, and promoting the circulation of blood benefit marrow arteries and veins, promotes the production of body fluid dense.”
Fructus Querci acutissimae: bitter in the mouth, puckery, slightly warm in nature; Return spleen, large intestine, kidney channel.Convergence is solid de-, hemostasis removing toxic substances.Main dysentery, has blood in stool, hemorrhoidal bleeding, proctoptosis, infantile hernia, and carbuncle sore is routed not mastitis for a long time, orchitis, face (black dry).Tang Materia Medica carries: " main dysentery, thick the intestines and stomach, fertile strong people.”
Herba Pouzolziae Zeylanicae: sweet in the mouth, light, cold in nature.Heat-clearing and toxic substances removing, swollen clearly evacuation of pus, relieving stranguria by diuresis.Main pyogenic skin infection and carbuncle-abscess, acute mastitis, acute toothache, dysentery, diarrhoea, urine leaching pain, nebulousurine." the SHENGCAO property of medicine standby will " carries: " the large skin infection of loose carbuncle infantile malnutrition (cellulitis), sterilization, controls acute mastitis breast carcinoma, beat slab sugar apply it with root, again can removing heat from blood.Only toothache, beats juice and water contains it.”
Symplocoris Paniculatae: bitter in the mouth, puckery, cold nature.Antiinflammatory softening the hard mass, regulating QI.Mainly for treating mammary gland is scorching, lymphadenitis, hernia, acute appendicitis, gastric cancer, furuncle.
Herba Arthraxonis Hispidi: bitter in the mouth, property is put down.Relieving cough and relieving asthma, parasite killing detoxifies.Main chronic cough asthma, hepatitis, pharyngolaryngitis, stomatitis, rhinitis, lymphadenitis, mastitis, skin infection scabies." property of medicine opinion " carries: " control all malignant boil.”
Herba Selaginellae Doederleinii: sweet in the mouth, micro-hardship, puckery, cool in nature.Heat-clearing and toxic substances removing, expelling wind and removing dampness.Main laryngopharynx swelling and pain, conjunctival congestion and swelling pain, cough due to lung-heat, mastitis, jaundice due to damp-heat, rheumatic arthralgia, traumatic hemorrhage.
Drymoglossum Herba Drymoglossi: sweet in the mouth, light, slightly cool in nature; Return liver, lung meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, hemostasis.Main jaundice due to damp-heat, conjunctival congestion and swelling pain, suppurative otitis media, parotitis, lymphadenitis, mange, traumatic injury.Guangzhou air force " conventional Chinese herbal medicine handbook " carries: " eliminating inflammation and expelling toxin, dispelling wind stopping cough.To harness the Yellow River subcutaneous ulcer, tuberculous lymphadenitis, parotitis, cough hemoptysis, rheumatic ostalgia, breast carcinoma, constipation due to dry stool.”
Nidus Vespae: taste is micro-sweet, property is put down, mild toxicity; Return liver, stomach, kidney channel.Wind-expelling pain-stopping, the detumescence of rose poison, killing parasites for relieving itching.Main air temperature arthralgia pain, wind carious pain, carbuncle malignant boil, scrofula, mouthpiece swells and ache, anal fistula, rubella pruritus, skin stubborn dermatitis.Japan hanako materia medica " carry: " control tooth pain, dysentery, acute mastitis; Honeybee stings, malignant boil, namely decocts and washes.”
Usnea: sweet in the mouth, hardship, property is put down; GUIXIN, kidney, lung meridian.Heat-clearing and toxic substances removing, relieving cough and resolving phlegm.For pulmonary tuberculosis (sodium salt of multiplex usnic acid), chronic bronchitis; Traumatic infection is controlled in external, and postoperative incision infects, suppurative otitis media, furuncle, tuberculous lymphadenitis, mastitis, burn, cervical erosion, trichomonas vaginitis." Chinese herbal medicine is commonly used in Tibet " carries: " heat-clearing and toxic substances removing, relieving cough and resolving phlegm.Control trauma infection contamination, pyogenic infection, venom, pulmonary tuberculosis cough with copious phlegm, cervical adenitis, mastitis.”
Semen Citri Reticulatae: bitter in the mouth, property is put down; Return liver, kidney, urinary bladder channel.Regulate the flow of vital energy, eliminating stagnation, pain relieving.Main hernia, painful and swollen testis, acute mastitis, lumbago.Essentials of Matea Medica carries: " row irritability, Sweeling-eliminating medicine powder poison.”
Herba Polygoni Perfoliati: sour in the mouth, hardship, property is put down; Return lung, small intestine meridian.Heat-clearing and toxic substances removing, inducing diuresis and reducing edema, dissipating blood stasis stops blooding.Main furuncle carbuncle, erysipelas, the paralysed cheek, mastitis, Ting ear, throat moth, cold, fever, cough due to lung-heat, pertussis, scrofula, haemorrhoids, lymphogranuloma inguinale inguinal bubo, dysentery, jaundice, tympanites, edema, stranguria with turbid discharge, leukorrhagia, malaria, wind-fire acute conjunctivitis, treating swelling and pain by traumatic injury, spits blood, has blood in stool, snake bite and insect sting." Chinese herbal medicine is commonly used in Shanghai " carries: " control oedema due to nephritis, wind-fire acute conjunctivitis, leukorrhagia, sting.”
Caulis et folium vitis thunbergii: sweet in the mouth, acid, property is put down; Return liver, stomach warp.Damp eliminating, diuresis, removing toxic substances.Control gonorrhea, dysentery, arthralgia pain, bolt for fastening a door from outside disease, hiccup, scrofula, acute mastitis, eczema, ecthyma." Fujian Chinese herbal medicine " carries: " cooling blood for hemostasis, subduing swelling and detoxicating.”
The present invention compared with prior art, has following beneficial effect:
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, all medicines are harmonious and have invigorating QI to consolidate the body surface resistance, the effects such as depressed liver-energy dispersing and QI regulating, blood circulation promoting and dispersing pathogen accumulation, anti-inflammatory analgetic, for treatment mammary fat sarcoma have determined curative effect, instant effect, cure rate high, have no side effect, safe and reliable, easy to use, low cost and other advantages, avoid the misery that operative treatment brings to people, the clinical treatment of mammary fat sarcoma can be widely used in.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The processing step of Chinese medicine preparation preparation method of the present invention is:
(1) by Herba Polygoni Runcinati, Herba youngiae japonicae with Caulis et folium vitis thunbergii puts into container, immerse 10 times amount volumetric concentration 70% alcohol solution dipping 4 hours, heating extraction, filter, after leaving standstill, reclaiming ethanol and being concentrated into 60 DEG C of relative densities is that the thick paste of 1.12-1.15 is for subsequent use;
(2) container is put in Radix fici panduratae, fermented glutinous rice, Fructus Querci acutissimae, Herba Pouzolziae Zeylanicae, Symplocoris Paniculatae, Herba Arthraxonis Hispidi, Herba Selaginellae Doederleinii, Drymoglossum Herba Drymoglossi, Usnea, Semen Citri Reticulatae and Herba Polygoni Perfoliati mixing, add the distilled water of 4 times amount, boil and extract 3 times, merge extractive liquid, filter, reserved filtrate is for subsequent use;
(3) Natrii Sulfas is put into container, smash to pieces and grind into powder, cross 100 order fine powders, for subsequent use;
(4) Nidus Vespae is cleaned, steam thoroughly, be cut into small pieces, fry to surperficial micro-yellow, take out, after cooling, smash to pieces and grind into powder, cross 120 order fine powders, for subsequent use;
(5) filtrate obtained to thick paste obtained for step (1), step (2) and step (3) and the obtained fine powder of step (4) are mixed, make tablet, be the Chinese medicine preparation being used for the treatment of mammary fat sarcoma of the present invention.
Usage and dosage: oral, each 2, every day 3 times 15 days is a course for the treatment of, and the lighter can fully recover 3 to 4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of mammary fat sarcoma, select the routine clinical observation of mammary fat sarcoma patients 200 that my institute or outer court make a definite diagnosis, patient is divided into two groups at random, treatment group 100 example, wherein male 50 example, women 50 example, age 28-76 year, 48 years old mean age, the course of disease 5 months-20 years; Matched group 100 example, wherein male 50 example, women 50 example, age 30-74 year, 50 years old mean age, the course of disease 5 months-18 years.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes Chinese medicine preparation of the present invention, adult every day 3 times, and each 2, warm water delivery service in half an hour after meal 15 days is a course for the treatment of, and taking 3 to 4 courses for the treatment of continuously can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes newborn numbness health, by specification use, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: the mammary fat sarcoma transference cures such as hypermastia, lump in breast, mammary gland dull pain, distending pain of the breast, breast hanging down, huge breast, health is fully recovered.
(2) effective: above-mentioned symptom is alleviated to some extent.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of Chinese medicine preparation of the present invention, cure 65 examples, effective 30 examples, invalid 5 examples, cure rate is 65%, total effective rate 95%.
Cure 35 examples in matched group, effective 20 examples, invalid 45 examples, cure rate is 35%, total effective rate 55%.
Above result display, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Shao, female, 72 years old, peasant, Anshan, liaoning Province people.Because there is the symptom of lump in patient's chest, just not bitterly, surface irregularity, edge boundary is unclear, and what push away is motionless, local skin systolic depression, and with discomfort uncomfortable in chest, spirit depressing, is off one's feed, stringy and thready pulse, is diagnosed as mammary fat sarcoma for matter.After taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, above-mentioned symptom thoroughly disappears, and follows up a case by regular visits to without recurrence, thoroughly cures.
2, Lin, female, 60 years old, retired worker, Sanming, Fujian Province people.There are swollen thing more than 15 years in the left breast of patient, as XIAOZAO is large during discovery, and rear slow increase, painless, once intermittently took multiple antibiotic medicine, DeGrain.After enter my institute and carry out a medical examination, be diagnosed as mammary fat sarcoma.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, swollen thing diminishes.Take 4 courses for the treatment of of Chinese medicine preparation of the present invention continuously, swollen thing disappears, and recovery from illness is not recurred so far.
3, Fang, man, 52 years old, retired cadre, people from Xinyu, Jiangxi.Find to suffer from mammary fat sarcoma when patient had a medical check-up before 2 years, in many places, hospitalize has no improvement.My institute treatment afterwards, after taking 1 course for the treatment of of Chinese medicine preparation of the present invention, health takes a turn for the better; Continue to take 2 courses for the treatment of of Chinese medicine preparation of the present invention, physical recovery is normal, follows up a case by regular visits to and does not recur, thoroughly fully recover.
4, virgin certain, man, 46 years old, driver, people from Zaozhuang, Shandong.Patient is to our hospital because there is the symptom such as lump in breast, mammary gland dull pain, and makes film, and is diagnosed as mammary fat sarcoma.After taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, above-mentioned symptom disappears completely, and livelihood restoration is normal, thoroughly cures.
5, Di, female, 38 years old, housewife, people from Liuzhou.Patient found there is goose pimples in oneself breast before 2 years, do color ultrasound be diagnosed as mammary fat tumor at local hospital, did not take a favorable turn, for further diagnosis and treatment are to our hospital after treatment a period of time.After take Chinese medicine preparation of the present invention, after taking 4 courses for the treatment of, above-mentioned symptom disappear, follow up a case by regular visits to recurrence, thoroughly cure.
6, rather certain, female, 26 years old, foreground, people from Zhuhai, Guangdong.Patient, because occurring that the symptoms such as lump in breast, distending pain of the breast, breast hanging down are come my institute and checked, is diagnosed as mammary fat sarcoma by fluoroscopy of chest inspection.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, swollen thing diminishes, and take 4 courses for the treatment of of Chinese medicine preparation of the present invention continuously, swollen thing disappears, and recovery from illness is not recurred so far.

Claims (5)

1. be used for the treatment of a Chinese medicine preparation for mammary fat sarcoma, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Herba Polygoni Runcinati 50-82 part Radix fici panduratae 50-82 part Herba youngiae japonicae 48-78 part Natrii Sulfas 42-70 part
Fermented glutinous rice 40-66 part Fructus Querci acutissimae 38-64 part Herba Pouzolziae Zeylanicae 35-60 part Symplocoris Paniculatae 30-55 part
Herba Arthraxonis Hispidi 28-48 part Herba Selaginellae Doederleinii 25-45 part Drymoglossum Herba Drymoglossi 22-42 part Nidus Vespae 22-42 part
Usnea 20-40 part Semen Citri Reticulatae 18-38 part Herba Polygoni Perfoliati 15-35 Fen Caulis et folium vitis thunbergii 10-30 part.
2. a kind of Chinese medicine preparation being used for the treatment of mammary fat sarcoma according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
63 parts, Herba Polygoni Runcinati 74 parts of Radix fici pandurataies 74 parts of Herba youngiae japonicae 70 parts of Natrii Sulfas
Fermented glutinous rice 59 parts of Fructus Querci acutissimaes 57 parts of Herba Pouzolziae Zeylanicae 53 portions of Symplocoris Paniculataes 49 parts
Herba Arthraxonis Hispidi 43 parts of Herba Selaginellae Doederleiniis 40 parts of Drymoglossum Herba Drymoglossis 37 parts of Nidus Vespaes 37 parts
Usnea 35 parts of Semen Citri Reticulataes 33 parts of Herba Polygoni Perfoliati 30 Fen Caulis et folium vitis thunbergii 25 parts.
3. a kind of Chinese medicine preparation being used for the treatment of mammary fat sarcoma according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
56 parts, Herba Polygoni Runcinati 66 parts of Radix fici pandurataies 66 parts of Herba youngiae japonicae 63 parts of Natrii Sulfas
Fermented glutinous rice 52 parts of Fructus Querci acutissimaes 51 parts of Herba Pouzolziae Zeylanicae 47 portions of Symplocoris Paniculataes 43 parts
Herba Arthraxonis Hispidi 38 parts of Herba Selaginellae Doederleiniis 35 parts of Drymoglossum Herba Drymoglossis 32 parts of Nidus Vespaes 32 parts
Usnea 30 parts of Semen Citri Reticulataes 28 parts of Herba Polygoni Perfoliati 25 Fen Caulis et folium vitis thunbergii 20 parts.
4. a kind of Chinese medicine preparation being used for the treatment of mammary fat sarcoma according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
49 parts, Herba Polygoni Runcinati 46 parts of Radix fici pandurataies 58 parts of Herba youngiae japonicae 56 parts of Natrii Sulfas
Fermented glutinous rice 47 parts of Fructus Querci acutissimaes 45 parts of Herba Pouzolziae Zeylanicae 41 portions of Symplocoris Paniculataes 37 parts
Herba Arthraxonis Hispidi 33 parts of Herba Selaginellae Doederleiniis 30 parts of Drymoglossum Herba Drymoglossis 27 parts of Nidus Vespaes 27 parts
Usnea 25 parts of Semen Citri Reticulataes 23 parts of Herba Polygoni Perfoliati 20 Fen Caulis et folium vitis thunbergii 15 parts.
5. the preparation method being used for the treatment of the Chinese medicine preparation of mammary fat sarcoma as described in claim 1-5, is characterized in that: comprise following processing step:
(1) by Herba Polygoni Runcinati, Herba youngiae japonicae with Caulis et folium vitis thunbergii puts into container, immerse 10 times amount volumetric concentration 70% alcohol solution dipping 4 hours, heating extraction, filter, after leaving standstill, reclaiming ethanol and being concentrated into 60 DEG C of relative densities is that the thick paste of 1.12-1.15 is for subsequent use;
(2) by Radix fici panduratae, fermented glutinous rice, Fructus Querci acutissimae, Herba Pouzolziae Zeylanicae, Symplocoris Paniculatae, Herba Arthraxonis Hispidi, Herba Selaginellae Doederleinii, Drymoglossum Herba Drymoglossi, Usnea, Semen Citri Reticulatae with shoulder .3 plate and return mixing to put into container, add the distilled water of 4 times amount, boil and extract 3 times, merge extractive liquid, filter, reserved filtrate is for subsequent use;
(3) Natrii Sulfas is put into container, smash to pieces and grind into powder, cross 100 order fine powders, for subsequent use;
(4) Nidus Vespae is cleaned, steam thoroughly, be cut into small pieces, fry to surperficial micro-yellow, take out, after cooling, smash to pieces and grind into powder, cross 120 order fine powders, for subsequent use;
(5) filtrate obtained to thick paste obtained for step (1), step (2) and step (3) and the obtained fine powder of step (4) are mixed, make tablet, be the described Chinese medicine preparation being used for the treatment of mammary fat sarcoma.
CN201410521287.2A 2014-10-04 2014-10-04 Traditional Chinese medicine preparation for treating breast liposarcoma and preparation method of traditional Chinese medicine preparation Pending CN104258147A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105963454A (en) * 2016-07-29 2016-09-28 张玮玮 Traditional Chinese medicine preparation for treating hyperplasia of mammary glands and preparation method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102614471A (en) * 2012-04-24 2012-08-01 山东大学齐鲁医院 Traditional Chinese medicine for treating breast carcinoma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102614471A (en) * 2012-04-24 2012-08-01 山东大学齐鲁医院 Traditional Chinese medicine for treating breast carcinoma

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105963454A (en) * 2016-07-29 2016-09-28 张玮玮 Traditional Chinese medicine preparation for treating hyperplasia of mammary glands and preparation method

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