CN103768457B - A kind of medicine and preparation method for the treatment of infantile anorexia - Google Patents

A kind of medicine and preparation method for the treatment of infantile anorexia Download PDF

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CN103768457B
CN103768457B CN201410062253.1A CN201410062253A CN103768457B CN 103768457 B CN103768457 B CN 103768457B CN 201410062253 A CN201410062253 A CN 201410062253A CN 103768457 B CN103768457 B CN 103768457B
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郭相君
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Abstract

The invention discloses a kind of medicine and preparation method for the treatment of infantile anorexia, belong to the field of Chinese medicines; The raw material of effective ingredient of the present invention consists of: Radix Brassicae rapae, Fructus Hordei nudi Germinatus, Fructus Colocasiae Esculentae, Fructus Aurantii, Folium Pruni pseudocerasi, Mel Alhagi, Rhizoma Euonymus Ke, Herba Artemisiae montanae Artemisia, Herba Thlaspis, Silurus asotus, Radix Fortunellae Margaritae, Mactraantiquata Spengler, Fructus Litchi, Folium Cleistocalycis Operculati, Semen coryli heterophyllae and Jasminum floridum Bge.; Chinese medicine preparation of the present invention selects high-quality Chinese crude drug scientific compatibility, there is effect of tonifying-Yin and nourishing-stomach, promoting the production of body fluid to quench thirst, invigorating the stomach and promoting digestion, warming middle-JIAO and strengthening the spleen, the vomiting, inappetence, diarrhoea, constipation, the abdominal distention that cause treatment infantile anorexia, the symptom such as suffer from abdominal pain and have blood in stool have significant curative effect, taking convenience, safe and reliable, treating both the principal and secondary aspects of a disease, without any side effects, can reach the object of curing infantile anorexia, should be widely promoted application.

Description

A kind of medicine and preparation method for the treatment of infantile anorexia
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine and preparation method for the treatment of infantile anorexia.
Background technology
Infantile anorexia is also known as digestive functional disturbance, and refer to that children's's longer-term loss of appetite or anorexia are main symptom, it is a kind of symptom, not one independently disease.Infantile anorexia is very common for period children's, and main symptom has vomiting, inappetence, diarrhoea, constipation, abdominal distention, suffers from abdominal pain and have blood in stool.These symptoms not only reflect gastral functional or organic disease, and when often appearing at the disease of other system, when being especially more common in central nervous system disease or mental disorder and multi-infection disease; Long-term anorexia, the trace element deficiency that needed by human body can be caused to want and infantile malnutrition, and can along with thirst and liking drink, flatulence is suffered from abdominal pain.
Infantile anorexia general less than 7 years old child falls ill more, and urban children sickness rate comparatively rural area is high, is considered to one of problem of mainly ingesting of affluent society child; Due to the long-term existence of apositia, cause child's body nutritional disorder, immunity degradation, and then the generation causing various disease, the normal growth having a strong impact on child is grown.
Current treatment is corrected except Bad Eating Habit to the children's of anorexia except helping sick child, and be difficult to improve infantile anorexia, therefore, the medicine developing new treatment infantile anorexia is the problem needing solution at present badly.
Summary of the invention
The invention provides a kind of medicine and preparation method for the treatment of infantile anorexia; Chinese medicine preparation of the present invention selects high-quality Chinese crude drug scientific compatibility, there is effect of tonifying-Yin and nourishing-stomach, promoting the production of body fluid to quench thirst, invigorating the stomach and promoting digestion, warming middle-JIAO and strengthening the spleen, the vomiting, inappetence, diarrhoea, constipation, the abdominal distention that cause treatment infantile anorexia, the symptom such as suffer from abdominal pain and have blood in stool have significant curative effect, taking convenience, safe and reliable, treating both the principal and secondary aspects of a disease, without any side effects, can reach the object of curing infantile anorexia, should be widely promoted application.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for infantile anorexia, raw material composition and the parts by weight of making described effective ingredient are:
Radix Brassicae rapae 53 ~ 79 parts of Fructus Hordei nudi Germinatus 50 ~ 76 portions of Fructus Colocasiae Esculentaes 42 ~ 68 parts of Fructus Aurantiis 37 ~ 64 parts
Folium Pruni pseudocerasi 37 ~ 63 parts of Mel Alhagi 33 ~ 62 parts of Rhizoma Euonymus Ke 33 ~ 62 parts of Herba Artemisiae montanae Artemisia 29 ~ 56 parts
Herba Thlaspis 28 ~ 55 Fen Silurus asotus 23 ~ 52 parts of Radix Fortunellae Margaritaes 21 ~ 51 parts of Mactraantiquata Spenglers 17 ~ 45 parts
Fructus Litchi 16 ~ 42 parts of Folium Cleistocalycis Operculati 13 ~ 39 portions of Semen coryli heterophyllaes 10 ~ 31 parts of Jasminum floridum Bge.s 8 ~ 27 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Radix Brassicae rapae 57 ~ 75 parts of Fructus Hordei nudi Germinatus 54 ~ 72 portions of Fructus Colocasiae Esculentaes 46 ~ 64 parts of Fructus Aurantiis 42 ~ 60 parts
Folium Pruni pseudocerasi 41 ~ 59 parts of Mel Alhagi 39 ~ 57 parts of Rhizoma Euonymus Ke 37 ~ 57 parts of Herba Artemisiae montanae Artemisia 36 ~ 51 parts
Herba Thlaspis 32 ~ 51 Fen Silurus asotus 27 ~ 47 parts of Radix Fortunellae Margaritaes 26 ~ 46 parts of Mactraantiquata Spenglers 22 ~ 40 parts
Fructus Litchi 20 ~ 38 parts of Folium Cleistocalycis Operculati 17 ~ 35 portions of Semen coryli heterophyllaes 14 ~ 27 parts of Jasminum floridum Bge.s 12 ~ 24 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Radix Brassicae rapae 62 ~ 70 parts of Fructus Hordei nudi Germinatus 59 ~ 67 portions of Fructus Colocasiae Esculentaes 51 ~ 59 parts of Fructus Aurantiis 47 ~ 55 parts
Folium Pruni pseudocerasi 46 ~ 54 parts of Mel Alhagi 44 ~ 52 parts of Rhizoma Euonymus Ke 42 ~ 50 parts of Herba Artemisiae montanae Artemisia 38 ~ 46 parts
Herba Thlaspis 37 ~ 45 Fen Silurus asotus 32 ~ 42 parts of Radix Fortunellae Margaritaes 31 ~ 41 parts of Mactraantiquata Spenglers 27 ~ 35 parts
Fructus Litchi 25 ~ 33 parts of Folium Cleistocalycis Operculati 22 ~ 30 portions of Semen coryli heterophyllaes 18 ~ 22 parts of Jasminum floridum Bge.s 16 ~ 20 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Radix Brassicae rapae 66 parts of Fructus Hordei nudi Germinatus 63 portions of Fructus Colocasiae Esculentaes 55 parts of Fructus Aurantiis 51 parts
Folium Pruni pseudocerasi 50 parts of Mel Alhagi 48 parts of Rhizoma Euonymus Ke 46 parts of Herba Artemisiae montanae Artemisia 42 parts
Herba Thlaspis 41 Fen Silurus asotus 37 parts of Radix Fortunellae Margaritaes 36 parts of Mactraantiquata Spenglers 31 parts
Fructus Litchi 29 parts of Folium Cleistocalycis Operculati 26 portions of Semen coryli heterophyllaes 20 parts of Jasminum floridum Bge.s 18 parts.
Treat a preparation method for the medicine of infantile anorexia, comprise following processing step:
(1) Radix Brassicae rapae, Folium Pruni pseudocerasi and Fructus Litchi are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(2) Fructus Hordei nudi Germinatus, Fructus Colocasiae Esculentae, Fructus Aurantii, Rhizoma Euonymus Ke, Herba Artemisiae montanae Artemisia, Herba Thlaspis, Silurus asotus and Radix Fortunellae Margaritae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 60 DEG C, relative density is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) get Mel Alhagi, Semen coryli heterophyllae and Jasminum floridum Bge. decontamination and carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Mactraantiquata Spengler and Folium Cleistocalycis Operculati are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 70% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.15 ~ 1.20 under filtrate simmer down to 65 DEG C of environment, for subsequent use;
(5) by juice, thick paste and the fine powder mixing obtained by above-mentioned steps (1) ~ (4), make tablet, obtain the medicine for the treatment of infantile anorexia of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Brassicae rapae: bitter in the mouth, pungent, sweet, warm in nature; GUIXIN, lung, spleen, stomach warp.The appetizing therapeutic method to keep the adverse QI flowing downwards, eliminating damp, detoxifying.Cure mainly accumulation of food in the stomach and intes tine due to indigestion, jaundice, quench one's thirst, pyretic toxicity swelling due to wind, furuncle, acute mastitis.Principle of Correct Diet carries: " warming middle-JIAO QI invigorating goes trusted subordinate's cold type of pain.”
Fructus Hordei nudi Germinatus: salty in the mouth, warm in nature.Help digestion, and in.Cure mainly food stagnation distension, inappetence, vomiting is had loose bowels." Japan hanako materia medica " carries: " appetizing, only cholera, except unhappy, expectorant is drunk, and broken disease is amassed, and can expedite the emergence of tire.”
Fructus Colocasiae Esculentae: sweet in the mouth, pungent, property is put down, and returns stomach warp.Spleen invigorating tonify deficiency, powder detoxifcation.Cure mainly weakness of the spleen and stomach, anorexia is weak, quenches one's thirst, scrofula, addiction block in abdomen, toxic swelling, wart, clavus, scabies, burn and scald.Supplement to the Herbal carries: " appetizing gulped down, logical intestinal closes, the removing blood stasis of cooking puerperal, drinks its juice, hemostasis, thirsty.”
Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature; Return spleen, stomach warp.Regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention, gastroptosis, proctoptosis, sub-official's prolapsus." Japan hanako materia medica " carries: " spleen benefiting and stimulating the appetite, adjust the five internal organs, the therapeutic method to keep the adverse QI flowing downwards, preventing or arresting vomiting is inverse, expectorant.Control regurgitation, cholera dysentery, helps digestion, and broken crux mass beside the umbilicus, five types of dysphagia, except wind improving eyesight and lung qi edema, sharp intestine and small intestine, skin is itched.Swollen can the processing of hemorrhoid is pressed." modern medicine study confirmation, Fructus Aurantii can produce diuresis by suppressing other effects such as reabsorption.
Folium Pruni pseudocerasi: sweet in the mouth, hardship, warm in nature, nontoxic; Return liver, spleen, lung meridian.Warming middle-JIAO and strengthening the spleen, cough-relieving is stopped blooding, removing toxic substances parasite killing.Cure mainly cold syndrome of the stomach food stagnation, diarrhoea, cough, spit blood, skin infection swells carbuncle, snake bite and insect sting, trichomonas vaginitis." book on Chinese herbal medicine is new again " carries: " nourishing the liver helps fire, spleen benefiting and stimulating the appetite, except the long-pending of gastral cavilty trembles with fear, helps digestion brokenly stagnant.”
Mel Alhagi: sweet in the mouth, acid, property is put down; GUIXIN, lung, spleen, small intestinal, kidney channel.Convergence astringing intestine to stop diarrhea, pain relieving.Cure mainly dysentery, diarrhoea, abdominal distention, hectic fever due to YIN-deficiency excessive thirst, headache, toothache.Supplement to the Herbal carries: " main bone heat, phlegmatic cough, the sudden and violent hematochezia of dysentery, appetizing, quenches the thirst, relieving restlessness.”
Rhizoma Euonymus Ke: mildly bitter flavor, puckery, warm in nature.Pleasantly to help digestion, stomach invigorating parasite killing.Cure mainly dyspeptic abdominal distention, malnutrition due to parasitic infestation is not changed.
Herba Artemisiae montanae Artemisia: bitter in the mouth, pungent, warm in nature.The appetizing of profit diaphragm.Staple food custom is depressed." medical center bun will " carries: " appetizing, row water.”
Herba Thlaspis: bitter in the mouth, sweet, cold nature; Return liver, kidney channel.Heat-clearing and toxic substances removing, expelling wind and removing dampness, inducing diuresis and reducing edema, and middle appetizing.For appendicitis, lung abscess, carbuncle furuncle and phyma poison, erysipelas, endometritis, leucorrhea, nephritis, cirrhotic ascites, infantile dyspepsia, rheumatic arthritis, lumbago, acute conjunctivitis, stomachache, hepatitis.
Silurus asotus: sweet in the mouth, property is put down; Return spleen channel.YIN nourishing is whetted the appetite, lactogenic diuresis.Cure mainly deficient deficiency, milk is few, aqueous vapor edema, dysuria." medical center bun will " carries: " YIN nourishing tonify deficiency, and spleen nourishes blood.”
Radix Fortunellae Margaritae: sour in the mouth, hardship, warm in nature; Return spleen, stomach, Liver Channel.Promoting QI to circulate and dispersing the agglomeration of the pathogens.Cure mainly stomachache and tell food, scrofula, hernia, puerperal abdonimal pain, uterine prolapse." east, Fujian book on Chinese herbal medicine " carries: " regulating QI sending down the abnormal ascending QI, spleen benefiting and stimulating the appetite, relaxing muscles and tendons and activating QI and blood in the collateral.Control breast stomachache, expectorant stagnant QI rising in reverse order, hernia and edema.”
Mactraantiquata Spengler: sweet in the mouth, salty, property is put down; Return Liver Channel.Nourishing YIN and benefiting blood, the cool liver of heat clearing away.Cure mainly Liver and kidney clothes empty, the acid of waist knee joint is heavy, and conjunctival congestion, quenches one's thirst." occupying diet spectrum with breath " carries: " appetizing is grown liquid and nourished heart, clearing heat for calming endogenous wind, removing heat in the liver for improving eyesight.”
Fructus Litchi: sweet in the mouth, acid, warm in nature; Return spleen, Liver Channel.To nourish blood spleen invigorating, promoting the circulation of QI for relieving swelling.Main body is after being ill empty, and Tianjin wound is thirsty, diarrhea due to hypofunction of the spleen, singultus, lack of appetite, scrofula, and furuncle swells, traumatic hemorrhage." Quanzhou book on Chinese herbal medicine " carries: " promoting the production of body fluid to quench thirst, throat, controls puerperal edema, insufficiency of the spleen hematochezia, laryngopharynx swelling and pain, the cards such as vomiting for tonifying YANG QI invigorating, invigorating middle warmer lung heat clearing.”
Folium Cleistocalycis Operculati: bitter in the mouth, cold in nature, mild toxicity.Heat clearing away disappears stagnant, removing toxic substances parasite killing.Cure mainly damp-heat dysentery, dyspeptic abdominal distention, acute mastitis, eczema, limb gas, mange, skin pruritus, cutter, gunshot wound.
Semen coryli heterophyllae: sweet in the mouth, property is put down.Invigorating the spleen and regulating the stomach, nourishing the lung to arrest cough.Main weak after being ill, diarrhea due to hypofunction of the spleen, inappetence, cough." Japan hanako materia medica " carries: " fertile white man, only hungry, in tune, appetizing.”
Jasminum floridum Bge.: bitter in the mouth, puckery, pungent, cold in nature; GUIXIN, spleen channel.Heat-clearing and toxic substances removing, dissipating blood stasis helps digestion.Cure mainly laryngopharynx swelling and pain, sore swollen toxin, traumatic injury, scald, knife injury, dyspeptic abdominal distention." Shaanxi medical herbs " carries: " granulation promoting, convergence.Control knife injury.”
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention selects high-quality Chinese crude drug scientific compatibility, there is effect of tonifying-Yin and nourishing-stomach, promoting the production of body fluid to quench thirst, invigorating the stomach and promoting digestion, warming middle-JIAO and strengthening the spleen, the vomiting, inappetence, diarrhoea, constipation, the abdominal distention that cause treatment infantile anorexia, the symptom such as suffer from abdominal pain and have blood in stool have significant curative effect, taking convenience, safe and reliable, treating both the principal and secondary aspects of a disease, without any side effects, can reach the object of curing infantile anorexia, should be widely promoted application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Radix Brassicae rapae 75g Fructus Hordei nudi Germinatus 72g Fructus Colocasiae Esculentae 64g Fructus Aurantii 60g
Folium Pruni pseudocerasi 59g Mel Alhagi 57g Rhizoma Euonymus Ke 57g Herba Artemisiae montanae Artemisia 51g
Herba Thlaspis 51g Silurus asotus 47g Radix Fortunellae Margaritae 46g Mactraantiquata Spengler 40g
Fructus Litchi 38g Folium Cleistocalycis Operculati 35g Semen coryli heterophyllae 27g Jasminum floridum Bge. 24g.
Treat a preparation method for the medicine of infantile anorexia, comprise following processing step:
(1) Radix Brassicae rapae, Folium Pruni pseudocerasi and Fructus Litchi are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(2) Fructus Hordei nudi Germinatus, Fructus Colocasiae Esculentae, Fructus Aurantii, Rhizoma Euonymus Ke, Herba Artemisiae montanae Artemisia, Herba Thlaspis, Silurus asotus and Radix Fortunellae Margaritae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 60 DEG C, relative density is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) get Mel Alhagi, Semen coryli heterophyllae and Jasminum floridum Bge. decontamination and carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Mactraantiquata Spengler and Folium Cleistocalycis Operculati are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 70% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.15 ~ 1.20 under filtrate simmer down to 65 DEG C of environment, for subsequent use;
(5) by juice, thick paste and the fine powder mixing obtained by above-mentioned steps (1) ~ (4), make tablet, obtain the medicine for the treatment of infantile anorexia of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every sheet 0.3g), warm water delivery service after meal; Within 4 days, be 1 course for the treatment of, 1 ~ 2 course for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
Radix Brassicae rapae 70g Fructus Hordei nudi Germinatus 67g Fructus Colocasiae Esculentae 59g Fructus Aurantii 55g
Folium Pruni pseudocerasi 54g Mel Alhagi 52g Rhizoma Euonymus Ke 50g Herba Artemisiae montanae Artemisia 46g
Herba Thlaspis 45g Silurus asotus 42g Radix Fortunellae Margaritae 41g Mactraantiquata Spengler 35g
Fructus Litchi 33g Folium Cleistocalycis Operculati 30g Semen coryli heterophyllae 22g Jasminum floridum Bge. 20g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
Radix Brassicae rapae 66g Fructus Hordei nudi Germinatus 63g Fructus Colocasiae Esculentae 55g Fructus Aurantii 51g
Folium Pruni pseudocerasi 50g Mel Alhagi 48g Rhizoma Euonymus Ke 46g Herba Artemisiae montanae Artemisia 42g
Herba Thlaspis 41g Silurus asotus 37g Radix Fortunellae Margaritae 36g Mactraantiquata Spengler 31g
Fructus Litchi 29g Folium Cleistocalycis Operculati 26g Semen coryli heterophyllae 20g Jasminum floridum Bge. 18g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
Radix Brassicae rapae 62g Fructus Hordei nudi Germinatus 59g Fructus Colocasiae Esculentae 51g Fructus Aurantii 47g
Folium Pruni pseudocerasi 46g Mel Alhagi 44g Rhizoma Euonymus Ke 42g Herba Artemisiae montanae Artemisia 38g
Herba Thlaspis 37g Silurus asotus 32g Radix Fortunellae Margaritae 31g Mactraantiquata Spengler 27g
Fructus Litchi 25g Folium Cleistocalycis Operculati 22g Semen coryli heterophyllae 18g Jasminum floridum Bge. 16g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
Radix Brassicae rapae 57g Fructus Hordei nudi Germinatus 54g Fructus Colocasiae Esculentae 46g Fructus Aurantii 42g
Folium Pruni pseudocerasi 41g Mel Alhagi 39g Rhizoma Euonymus Ke 37g Herba Artemisiae montanae Artemisia 36g
Herba Thlaspis 32g Silurus asotus 27g Radix Fortunellae Margaritae 26g Mactraantiquata Spengler 22g
Fructus Litchi 20g Folium Cleistocalycis Operculati 17g Semen coryli heterophyllae 14g Jasminum floridum Bge. 12g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine for the treatment of infantile anorexia, select the routine clinical observation of infantile anorexia patient 180 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 90 example, wherein male 46 example, women 44 example, 2 ~ 7 years old age, 4.5 years old mean age, the course of disease 6 months; Matched group 90 example, wherein male 45 example, women 45 example, 3 ~ 6 years old age, 4.5 years old mean age, the course of disease 5 months;
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every sheet 0.3g), warm water delivery service after meal; Within 4 days, be 1 course for the treatment of, 1 ~ 2 course for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes children's's JIANWEI XIAOSHI PIAN, oral, one time 2 ~ 3,3 times on the one, or follow the doctor's advice.
3, efficacy determination:
(1) cure: anorexia disappears completely, diet recovers normal.
(2) effective: anorexia obviously alleviates, simultaneous phenomenon improves.
(3) effective: anorexia alleviates to some extent, simultaneous phenomenon is alleviated.
(4) invalid: anorexia is unchanged or increase the weight of, and simultaneous phenomenon is without improvement.
4, result:
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, certain is appointed, female, 3 years old, people from Hengshui, Hebei.Patient suffers from apositia two months, and hospital gave multiple injection treatment, had no sign of improvement, and introduced to our hospital through friend, and after taking 1 course for the treatment of of invention Drug therapy, anorexia is clearly better, and fully recovers after continuing to take 1 course for the treatment of.
2, Tan, man, 4 years old, people from Changzhi, Shanxi.Patient's inappetence more than three months, the indigestion and loss of appetite anorexia of infant, with shallow complexion, abdominal part swells, lean body mass, neurolysis, the sparse fibring of hair, irritable, and large dry stool is rare uncomfortable, and child more of the same age is low for head.Thick fur is greasy, thready and weak pulse without strength.After taking 1 course for the treatment of of medicine of the present invention, namely patient's appetite take a favorable turn, and after taking 1 course for the treatment of of medicine of the present invention, appetite recovers normal completely.Visit after half a year, patient has rosy cheeks, and everyway has recovered normal.
3, the summer, man, 3 years old, people from Dalian.Patient's anorexia January, even if slightly enter after diet then eats, lassitude, looks into that matter is light, white and thin fur, and examine as pattern of Spleen Qi deficiency anorexia, give Drug therapy of the present invention, after taking 1 course for the treatment of, infant anorexia disappears, and recovers normal, follows up a case by regular visits to that all are normal after half a year.
4, clock, female, 4 years old, people from Changchun, Jilin.Patient's vomiting, inappetence, diarrhoea, constipation, abdominal distention, the symptom such as suffer from abdominal pain and have blood in stool, infantile anorexia is suffered from through diagnosis, have no sign of improvement with crossing multi-medicament, to our hospital after being introduced, after taking 1 course for the treatment of of Chinese medicine preparation of the present invention, above-mentioned symptom is clearly better, and fully recovers, follow up a case by regular visits to without recurrence after half a year after continuing to take 1 course for the treatment of of medicine of the present invention.
5, the Yan, female, 5 years old, people from Huaian, Jiangsu.Patient's inappetence, distension and fullness in the abdomen, feel sick, dysphoria, constipation with dry stool half a year, look into thick and greasy fur, examine as dyspepsia type anorexia, take Drug therapy of the present invention, fully recover after taking 2 courses for the treatment of, follow up a case by regular visits to half a year without recurrence, infant is without any untoward reaction, and three large routine tests and hepatic and renal function detect no abnormal.
6, thunder, man, 6 years old, Zhejiang Huzhou people.Patient's anorexia, nauseating, distension and fullness in the abdomen, be diagnosed as infantile anorexia after diagnosing, take Drug therapy of the present invention, fully recover after taking 1 course for the treatment of, and follow up a case by regular visits to three months without recurrence, infant is without any untoward reaction, and routine test indices is no abnormal.

Claims (5)

1. treat a medicine for infantile anorexia, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix Brassicae rapae 53 ~ 79 parts of Fructus Hordei nudi Germinatus 50 ~ 76 portions of Fructus Colocasiae Esculentaes 42 ~ 68 parts of Fructus Aurantiis 37 ~ 64 parts
Folium Pruni pseudocerasi 37 ~ 63 parts of Mel Alhagi 33 ~ 62 parts of Rhizoma Euonymus Ke 33 ~ 62 parts of Herba Artemisiae montanae Artemisia 29 ~ 56 parts
Herba Thlaspis 28 ~ 55 Fen Silurus asotus 23 ~ 52 parts of Radix Fortunellae Margaritaes 21 ~ 51 parts of Mactraantiquata Spenglers 17 ~ 45 parts
Fructus Litchi 16 ~ 42 parts of Folium Cleistocalycis Operculati 13 ~ 39 portions of Semen coryli heterophyllaes 10 ~ 31 parts of Jasminum floridum Bge.s 8 ~ 27 parts;
The medicine making described treatment infantile anorexia is following processing step:
(1) Radix Brassicae rapae, Folium Pruni pseudocerasi and Fructus Litchi are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(2) Fructus Hordei nudi Germinatus, Fructus Colocasiae Esculentae, Fructus Aurantii, Rhizoma Euonymus Ke, Herba Artemisiae montanae Artemisia, Herba Thlaspis, Silurus asotus and Radix Fortunellae Margaritae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 60 DEG C, relative density is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) get Mel Alhagi, Semen coryli heterophyllae and Jasminum floridum Bge. decontamination and carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Mactraantiquata Spengler and Folium Cleistocalycis Operculati are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 70% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.15 ~ 1.20 under filtrate simmer down to 65 DEG C of environment, for subsequent use;
(5) by juice, thick paste and the fine powder mixing obtained by above-mentioned steps (1) ~ (4), make tablet, obtain the medicine of described treatment infantile anorexia.
2. a kind of medicine for the treatment of infantile anorexia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix Brassicae rapae 57 ~ 75 parts of Fructus Hordei nudi Germinatus 54 ~ 72 portions of Fructus Colocasiae Esculentaes 46 ~ 64 parts of Fructus Aurantiis 42 ~ 60 parts
Folium Pruni pseudocerasi 41 ~ 59 parts of Mel Alhagi 39 ~ 57 parts of Rhizoma Euonymus Ke 37 ~ 57 parts of Herba Artemisiae montanae Artemisia 36 ~ 51 parts
Herba Thlaspis 32 ~ 51 Fen Silurus asotus 27 ~ 47 parts of Radix Fortunellae Margaritaes 26 ~ 46 parts of Mactraantiquata Spenglers 22 ~ 40 parts
Fructus Litchi 20 ~ 38 parts of Folium Cleistocalycis Operculati 17 ~ 35 portions of Semen coryli heterophyllaes 14 ~ 27 parts of Jasminum floridum Bge.s 12 ~ 24 parts.
3. a kind of medicine for the treatment of infantile anorexia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix Brassicae rapae 62 ~ 70 parts of Fructus Hordei nudi Germinatus 59 ~ 67 portions of Fructus Colocasiae Esculentaes 51 ~ 59 parts of Fructus Aurantiis 47 ~ 55 parts
Folium Pruni pseudocerasi 46 ~ 54 parts of Mel Alhagi 44 ~ 52 parts of Rhizoma Euonymus Ke 42 ~ 50 parts of Herba Artemisiae montanae Artemisia 38 ~ 46 parts
Herba Thlaspis 37 ~ 45 Fen Silurus asotus 32 ~ 42 parts of Radix Fortunellae Margaritaes 31 ~ 41 parts of Mactraantiquata Spenglers 27 ~ 35 parts
Fructus Litchi 25 ~ 33 parts of Folium Cleistocalycis Operculati 22 ~ 30 portions of Semen coryli heterophyllaes 18 ~ 22 parts of Jasminum floridum Bge.s 16 ~ 20 parts.
4. a kind of medicine for the treatment of infantile anorexia according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Radix Brassicae rapae 66 parts of Fructus Hordei nudi Germinatus 63 portions of Fructus Colocasiae Esculentaes 55 parts of Fructus Aurantiis 51 parts
Folium Pruni pseudocerasi 50 parts of Mel Alhagi 48 parts of Rhizoma Euonymus Ke 46 parts of Herba Artemisiae montanae Artemisia 42 parts
Herba Thlaspis 41 Fen Silurus asotus 37 parts of Radix Fortunellae Margaritaes 36 parts of Mactraantiquata Spenglers 31 parts
Fructus Litchi 29 parts of Folium Cleistocalycis Operculati 26 portions of Semen coryli heterophyllaes 20 parts of Jasminum floridum Bge.s 18 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the medicine of infantile anorexia, it is characterized in that: be following processing step:
(1) Radix Brassicae rapae, Folium Pruni pseudocerasi and Fructus Litchi are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(2) Fructus Hordei nudi Germinatus, Fructus Colocasiae Esculentae, Fructus Aurantii, Rhizoma Euonymus Ke, Herba Artemisiae montanae Artemisia, Herba Thlaspis, Silurus asotus and Radix Fortunellae Margaritae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, at simmer down to 60 DEG C, relative density is the thick paste of 1.10 ~ 1.16, for subsequent use;
(3) get Mel Alhagi, Semen coryli heterophyllae and Jasminum floridum Bge. decontamination and carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Mactraantiquata Spengler and Folium Cleistocalycis Operculati are cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 70% of 8 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.15 ~ 1.20 under filtrate simmer down to 65 DEG C of environment, for subsequent use;
(5) by juice, thick paste and the fine powder mixing obtained by above-mentioned steps (1) ~ (4), make tablet, obtain the medicine of described treatment infantile anorexia.
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CN104247817A (en) * 2014-09-25 2014-12-31 李雪壮 Cleistocalyx operculatus tea and preparation method thereof
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CN110638940A (en) * 2019-11-06 2020-01-03 庆阳市西峰区妇幼保健计划生育服务中心 External traditional Chinese medicine composition for treating infantile anorexia and monophagia and application thereof

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