CN103933402A - Traditional Chinese medicine preparation for treating brain tumor and preparation method - Google Patents
Traditional Chinese medicine preparation for treating brain tumor and preparation method Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating brain tumor and a preparation method, belonging to the field of traditional Chinese medicine. The traditional Chinese medicine preparation comprises the following active ingredients: asiatic pennywort herb, thallus laminariae, green bean starch, bitter sow thistle, indian stringbush root, radish leaf, chestnut leaf, wild buckwheat root, black eragrostis, wood ear, saint ignatius bean, kalimeris, hog plum, impure mirabilite, ligustrum japonium and pu-er tea. The traditional Chinese medicine preparation is compatible for the selected active ingredients, meets the theories of traditional Chinese medicine and pharmacology and modern medicine and pharmacology, has the effects of invigorating the circulation of blood, dispersing blood stasis and enlightening, and relieving swelling and pain, as well as obvious curative effects on treating symptoms of mental disorders and the like caused by brain tumor, is short in treatment course and fast to effect so as to enable the patient with brain tumor to get rid of pain, the patient with the brain tumor does not reoccur after being healed, and the traditional Chinese medicine preparation is safe and reliable, has no any toxic and side effects, exact in curative effect, can achieve the purposes of treating both manifestation and roots cause of disease, thus being worthy of clinically wide popularization and application.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation and preparation method for the treatment of cerebroma.
Background technology
The cerebral tumor is one of disease common in nervous system, human nervous system's function is had to very large harm, generally be divided into former and the large class of secondary two, primary brain tumors can betide cerebral tissue, meninges, cranial nerve, hypophysis, the remaining embryonal tissue of blood vessel etc., and secondary tumors refers to the Malignant tumor of bonal metastasis at other position of health or the metastatic tumor that Intracranial invasion forms.
The cerebral tumor can betide any age, with 20～50 years old for the most common.Juvenile is more common with posterior cranial fossa and center line tumor, is mainly medulloblastoma, craniopharyngioma and ependymoma.Adult is with cerebral hemisphere glioma for the most common, and as astrocytoma, glioblastoma multiforme, ependymoma etc., next is meningioma, pituitary tumor and craniopharyngioma, neurofibroma, cavernous hemangioma, cholesteatoma etc.Primary intracranial tumor incidence rate is without obvious sex difference, and man is slightly more than female.Oncogene may reside in normal cell, not expressing tumor characteristic, do the used time when this like cell is subject to tumorigenesis factor, as virus, chemical tumorigenesis and ray etc., the oncogene in cell is activated, the phenotype of cell changes, tumor character is expressed, and these cells increase rapidly, thereby forms real tumor entity, think at present, induced tumor occur because have: inherited genetic factors, physical factor, chemical factor and oncogenic virus.
In recent years, cerebral tumor sickness rate is in rising trend, according to statistics, the cerebral tumor accounts for 5% of general tumour, account for 70% of pediatric tumor, proceed to intracranial and other malignant tumor finally has 20～30%, due to the infiltrative growth of its expansion, at intracranial once occupy certain space, no matter its character is optimum or pernicious, all certainly will make intracranial pressure raise, compressing cerebral tissue, cause nervus centralis infringement, jeopardize patient's life.
Because the harm of cerebroma is large, seriously affect patient's healthy and quality of life, treatment cerebroma does not still have effective medicine, can only give anti symptom treatment, brings very big misery to patient.Therefore, become medically one of important topic for studying a kind of Chinese medicine preparation that can effectively treat cerebroma.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of cerebroma; The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has that blood circulation promoting and dispersing pathogen accumulation, blood stasis dispelling are had one's ideas straightened out, effect of reducing swelling and alleviating pain, the symptoms such as the mental disorder that treatment cerebroma is occurred together have significant curative effect, short treating period, instant effect, makes Patients with Brain Tumors break away from misery, non-relapse after healing, safe and reliable, without any side effects, determined curative effect, can reach the object for the treatment of both the principal and secondary aspects of a disease, wide popularization and application on clinic.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for cerebroma, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
35～57 parts of 35～59 parts of Herba Sonchi Oleracei of 36～60 parts of green starchs of 38～62 parts of Thallus Laminariae (Thallus Eckloniae)s of Herba Centellae
32～56 parts of 33～57 parts of Radix Et Rhizoma Fagopyri Tatarici of 33～57 parts of Folium Castaneae of 34～58 parts of Folium Raphani of Radix Wikstroemae
29～53 parts of 29～53 parts of Herba Kalimeridis of 30～54 parts of Semen Ignatii of 32～56 portions of Auricularias of Radix Cyanotis vagae
18～42 parts of 23～47 parts of Folium camelliae assamicaes of 26～50 parts of Fructus Ligustri Lucidi of 27～51 parts of Mirabilitum of Fructus Choerospondiatis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
39～55 parts of 39～55 parts of Herba Sonchi Oleracei of 40～56 parts of green starchs of 42～58 parts of Thallus Laminariae (Thallus Eckloniae)s of Herba Centellae
36～52 parts of 37～53 parts of Radix Et Rhizoma Fagopyri Tatarici of 37～53 parts of Folium Castaneae of 38～54 parts of Folium Raphani of Radix Wikstroemae
33～49 parts of 33～49 parts of Herba Kalimeridis of 34～50 parts of Semen Ignatii of 36～52 portions of Auricularias of Radix Cyanotis vagae
22～38 parts of 27～43 parts of Folium camelliae assamicaes of 30～46 parts of Fructus Ligustri Lucidi of 31～47 parts of Mirabilitum of Fructus Choerospondiatis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
43～51 parts of 43～51 parts of Herba Sonchi Oleracei of 44～52 parts of green starchs of 46～54 parts of Thallus Laminariae (Thallus Eckloniae)s of Herba Centellae
40～48 parts of 41～49 parts of Radix Et Rhizoma Fagopyri Tatarici of 41～49 parts of Folium Castaneae of 42～50 parts of Folium Raphani of Radix Wikstroemae
37～45 parts of 36～45 parts of Herba Kalimeridis of 38～46 parts of Semen Ignatii of 40～48 portions of Auricularias of Radix Cyanotis vagae
26～34 parts of 31～39 parts of Folium camelliae assamicaes of 34～42 parts of Fructus Ligustri Lucidi of 35～43 parts of Mirabilitum of Fructus Choerospondiatis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
47 parts of 47 parts of Herba Sonchi Oleracei of 48 parts of green starchs of 50 parts of Thallus Laminariae (Thallus Eckloniae)s of Herba Centellae
44 parts of 45 parts of Radix Et Rhizoma Fagopyri Tatarici of 45 parts of Folium Castaneae of 46 parts of Folium Raphani of Radix Wikstroemae
41 parts of 41 parts of Herba Kalimeridis of 42 parts of Semen Ignatii of 44 portions of Auricularias of Radix Cyanotis vagae
30 parts of 35 parts of Folium camelliae assamicaes of 38 parts of Fructus Ligustri Lucidi of 39 parts of Mirabilitum of Fructus Choerospondiatis.
Treat a preparation method for the Chinese medicine preparation of cerebroma, comprise following processing step:
(1) Herba Centellae, Radix Et Rhizoma Fagopyri Tatarici and Fructus Choerospondiatis are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
(2) Thallus Laminariae (Thallus Eckloniae), Radix Wikstroemae, Folium Castaneae, Auricularia, Fructus Ligustri Lucidi and Folium camelliae assamicae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 DEG C, relative density is 1.10～1.13, for subsequent use;
(3) get the distilled water that green starch adds 3 times of amounts, heated and boiled also stirs, and makes it to reconcile into gluey gelatinized corn starch, for subsequent use;
(4) Herba Sonchi Oleracei, Folium Raphani and Herba Kalimeridis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) get Semen Ignatii decontamination, add water and mill as extract, for subsequent use;
(6) Radix Cyanotis vagae and Mirabilitum are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(7) above-mentioned steps (1)～(6) prepared thick paste, gluey gelatinized corn starch, juice, extract and fine powder are mixed, make capsule, obtain the Chinese medicine preparation for the treatment of cerebroma of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Centellae: bitter in the mouth, pungent, cold in nature; Return liver,spleen,kidney warp.Clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Cure mainly conjunctival congestion and swelling pain.Modern medicine study confirmation, Herba Centellae water extract has the effect of anti-inflammation.
Thallus Laminariae (Thallus Eckloniae): salty in the mouth, cold in nature; Return liver, stomach, kidney channel.Hard masses softening and resolving, little expectorant diuretic.For goiter, scrofula, painful and swollen testis, phlegm retention edema." modern Practical Chinese medicinal " carries: " swollen, drench disease, wet beriberi.Control again goiter, chronic tracheitis, cough.”
Green starch: viscosity foot, water absorption is little, and color is pure white and glossy.Modern medicine study confirmation, green starch has antibacterial and bacteriostasis, effect for reducing blood fat, antitumor action, Detoxication etc.
Herba Sonchi Oleracei: bitter in the mouth, cold in nature; Enter the heart, spleen, stomach three warps.Heat-clearing and toxic substances removing, removing blood stasis with potent drugs is invigorated blood circulation, evacuation of pus.For appendicitis, peritoneal abscess, enteritis, dysentery, acute and chronic pelvic inflammatory disease, cough due to lung-heat, pulmonary tuberculosis, spits blood, epistaxis; Traumatic injury is controlled in external, and furuncle swells and ache, impetigo, eczema scrotum.
Radix Wikstroemae: bitter in the mouth, sweet, property is flat; Enter the heart, lung, small intestine meridian.Heat-clearing and toxic substances removing, eliminating stagnation is relieved oedema or abdominal distension through diuresis or purgation.For cough due to lung-heat, mumps, scrofula, rheumatic arthralgia, furuncle toxic swelling, edema abdominal distention." Traditional Chinese Medicine in Sichuan will " carries:
" wind-damp dispelling, point pure and impure, sharp joint, separates sore.Dispelling the wind and dampness pathogens pain, waist knee joint arthralgia pain, stranguria with turbid discharge and syphilis malignant boil.”
Folium Raphani: acrid in the mouth, hardship, warm in nature.Dyspepsia and intestinal stasis relieving, does not disappear for controlling dyspepsia, and chest and diaphragm feeling of fullness does oh to wait disease.Also has the function of moistening and cleaning throat stomach function regulating.The eliminating stagnation of regulating the flow of vital energy, for married woman's breast knot, galactostasis, laryngopharynx swelling and pain, damp-heat dysentery etc.
Folium Castaneae: taste is micro-sweet, property is flat.Clearing away lung-heat to relieve cough, removing toxic substances and promoting subsidence of swelling.Main pertussis, pulmonary tuberculosis, swelling throat disease, toxic swelling, dermatitis rhus." modern Practical Chinese medicinal " carries: " be astringent.External is coated with dermatitis rhus.”
Radix Et Rhizoma Fagopyri Tatarici: sweet in the mouth, property is flat, mild toxicity; Return spleen, stomach, large intestine channel.Spleen invigorating row is stagnant, regulating QI to relieve pain, removing toxic substances and promoting subsidence of swelling.Cure mainly epigastric distending pain, dyspepsia, dysentery, lumbago and skelalgia, traumatic injury, carbuncle malignant boil, lyssodexis." Inner Mongol Chinese herbal medicine " carries: " removing damp and stopping pain, removing toxic substances and promoting subsidence of swelling, stomach invigorating.Control traumatic injury, lumbago and skelalgia, sore and toxic, dyspepsia.”
Radix Cyanotis vagae: sweet in the mouth, property is flat.Dispelling, collateral-activating, inducing diuresis and reducing edema, move back weakness.For rheumatic arthritis, lumbago and skelalgia, oedema due to nephritis, deficiency-heat is not moved back; Eczema is controlled in external, tinea pedis, knife injury.
Auricularia: sweet in the mouth, property is flat; Return lung, stomach, liver,spleen,kidney, large intestine channel.Benefiting qi and nourishing blood, nourishing the lung to arrest cough, hemostasis blood pressure lowering, anticancer.Main Qi and blood deficiency, chronic cough of deficiency lung, hemoptysis, epistaxis, dysentery, bleeding hemorrhoids, woman uterine bleeding, hypertension, retinal hemorrhage, cervical cancer, cancer of vagina, traumatic pain." occupying diet spectrum with breath " carries: " the resistance to famine of QI invigorating, invigorates blood circulation, and controls tumbling down wound.All pouring dysentery that collapses, hemorrhoid are suffered from hemorrhoidal hamorrhage, and normal food can recover.”
Semen Ignatii: bitter in the mouth, cold in nature, greatly poison; Return spleen, stomach warp.Removing toxic substances and promoting subsidence of swelling, parasite killing pain relieving.Main stomachache dysentery, malaria, children's ascarid, knife injury is hemorrhage, head sore, hemorrhoid, snake bite and insect sting." detailed outline is picked up any lost article from the road " carries: " control bellyache and diarrhea profit, malaria, malnutrition due to parasitic infestation, knife injury is hemorrhage, centipete bite.”
Herba Kalimeridis: acrid in the mouth, hardship, cold in nature.Heat-clearing and toxic substances removing, dissipating blood stasis hemostasis, removing food stagnancy.For cat fever, cough, acute pharyngitis, tonsillitis, mumps, infectious hepatitis, Stomach duodenum ulcer, infantile malnutrition, enteritis, dysentery, spits blood, metrorrhagia, menoxenia; External is controlled furuncle and is swollen and ache, mastitis, traumatic hemorrhage." Traditional Chinese Medicine in Sichuan will " carries: " the long-pending glutted and breast knot flatulence that helps digestion, except damp and hot, diuresis, brings down a fever, and cough-relieving is coughed, removing toxic substances, treating snakebite.”
Fructus Choerospondiatis: sweet in the mouth, acid, property is flat; Return spleen, Liver Channel.Promoting flow of QI and blood, tranquilizing by nourishing the heart, removing food stagnancy removing toxic substances.Main qi depression to blood stasis, chest pain, shortness of breath and palpitation, neurasthenia, insomnia, bronchitis, dyspepsia abdominal distention, diarrhoea, hernia, burn and scald." Guangxi Chinese herbal medicine " carries: " fresh fruit, eliminating indigested food are controlled dyspepsia stomachache.Pit, heat clearing away poison, parasite killing convergence.Control burn.”
Mirabilitum: acrid in the mouth, bitter salty, cold in nature; Return stomach, large intestine channel.Purge heat, moisturize, softening the hard mass.Control excess-heat stagnant, abdominal distention constipation, retention of phlegm gathers, conjunctival congestion and swelling pain, sore throat, carbuncle." Japan hanako materia medica " carries: " the main the five internal organs crux of removing heat by catharsis.Control a day capable hot disease, detumescence poison and headache, evacuation of pus, profit hair.Allly enter to drink medicine, be first satisfied with, in small cup, to stir the medicine of a warm nature and water clothes.”
Fructus Ligustri Lucidi: sweet in the mouth, hardship, property is flat; Return liver, kidney channel.Liver and kidney tonifying, clearind deficient heat, improving eyesight.Fructus Ligustri Lucidi has enhancing immunologic function, and rising peripheral leukocytes strengthens reticuloendothelial system phagocytic activity, strengthens the effect of cellular immunization and humoral immunization; Have heart tonifying, diuresis and protect the liver, cough-relieving, cathartic, the effect such as antibacterial, anticancer.Clinic study shows, Fructus Ligustri Lucidi can obviously improve T lymphocyte function, and Fructus Ligustri Lucidi promotes the activity of T cell by strengthening the activity of cell surface receptor; Can strengthen cellular immune function, skin bubble method is surveyed macrophage phagocytic function and blood lymphocytes rosette is significantly increased.
Folium camelliae assamicae: bitter in the mouth, sweet, cold in nature; Return liver, stomach warp.Clearing away heat and promoting production of body fluid, wards off dirty removing toxic substances, helps digestion and relieves the effect of alcohol, refreshment rash.Cure mainly administration's heat thirsty, headache blurred vision, eruptive disease stomachache, dysentery, meat stagnation, alcoholism, Mental fatigue hypersomnia, measles is sent out not smooth thoroughly." detailed outline is picked up any lost article from the road " carries: " separate greasy cattle and sheep poison, by the expectorant therapeutic method to keep the adverse QI flowing downwards, postcibal diarrhea is removed heat by catharsis, and relieving alcoholic intoxication eliminates indigestion and phlegm, and clearing stomach is promoted the production of body fluid, and power is especially large.”
The present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention has the symptoms such as blood circulation promoting and dispersing pathogen accumulation, blood stasis dispelling are had one's ideas straightened out, effect of reducing swelling and alleviating pain, the mental disorder that treatment cerebroma is occurred together and has significant curative effect, short treating period, and instant effect, makes Patients with Brain Tumors break away from misery, non-relapse after healing.
2, the selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meets Chinese medicine and pharmacy and modern medicine theory, safe and reliable, without any side effects, and determined curative effect can reach the object for the treatment of both the principal and secondary aspects of a disease, wide popularization and application on clinic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Herba Centellae 58g Thallus Laminariae (Thallus Eckloniae) 56g green starch 55g Herba Sonchi Oleracei 55g
Radix Wikstroemae 54g Folium Raphani 53g Folium Castaneae 53g Radix Et Rhizoma Fagopyri Tatarici 52g
Radix Cyanotis vagae 52g Auricularia 50g Semen Ignatii 49g Herba Kalimeridis 49g
Fructus Choerospondiatis 47g Mirabilitum 46g Fructus Ligustri Lucidi 43g Folium camelliae assamicae 38g.
Treat a preparation method for the Chinese medicine preparation of cerebroma, comprise following processing step:
(1) Herba Centellae, Radix Et Rhizoma Fagopyri Tatarici and Fructus Choerospondiatis are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
(2) Thallus Laminariae (Thallus Eckloniae), Radix Wikstroemae, Folium Castaneae, Auricularia, Fructus Ligustri Lucidi and Folium camelliae assamicae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 DEG C, relative density is 1.10～1.13, for subsequent use;
(3) get the distilled water that green starch adds 3 times of amounts, heated and boiled also stirs, and makes it to reconcile into gluey gelatinized corn starch, for subsequent use;
(4) Herba Sonchi Oleracei, Folium Raphani and Herba Kalimeridis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) get Semen Ignatii decontamination, add water and mill as extract, for subsequent use;
(6) Radix Cyanotis vagae and Mirabilitum are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(7) above-mentioned steps (1)～(6) prepared thick paste, gluey gelatinized corn starch, juice, extract and fine powder are mixed, make capsule, obtain the Chinese medicine preparation for the treatment of cerebroma of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 15 days, be 1 course for the treatment of, can fully recover 2～4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Herba Centellae 54g Thallus Laminariae (Thallus Eckloniae) 52g green starch 51g Herba Sonchi Oleracei 51g
Radix Wikstroemae 50g Folium Raphani 49g Folium Castaneae 49g Radix Et Rhizoma Fagopyri Tatarici 48g
Radix Cyanotis vagae 48g Auricularia 46g Semen Ignatii 45g Herba Kalimeridis 45g
Fructus Choerospondiatis 43g Mirabilitum 42g Fructus Ligustri Lucidi 39g Folium camelliae assamicae 34g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Herba Centellae 50g Thallus Laminariae (Thallus Eckloniae) 48g green starch 47g Herba Sonchi Oleracei 47g
Radix Wikstroemae 46g Folium Raphani 45g Folium Castaneae 45g Radix Et Rhizoma Fagopyri Tatarici 44g
Radix Cyanotis vagae 44g Auricularia 42g Semen Ignatii 41g Herba Kalimeridis 41g
Fructus Choerospondiatis 39g Mirabilitum 38g Fructus Ligustri Lucidi 35g Folium camelliae assamicae 30g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Herba Centellae 46g Thallus Laminariae (Thallus Eckloniae) 44g green starch 43g Herba Sonchi Oleracei 43g
Radix Wikstroemae 42g Folium Raphani 41g Folium Castaneae 41g Radix Et Rhizoma Fagopyri Tatarici 40g
Radix Cyanotis vagae 40g Auricularia 38g Semen Ignatii 36g Herba Kalimeridis 37g
Fructus Choerospondiatis 35g Mirabilitum 34g Fructus Ligustri Lucidi 31g Folium camelliae assamicae 26g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
Raw material composition and the weight of Chinese medicine preparation effective ingredient of the present invention are:
Herba Centellae 42g Thallus Laminariae (Thallus Eckloniae) 40g green starch 39g Herba Sonchi Oleracei 39g
Radix Wikstroemae 38g Folium Raphani 37g Folium Castaneae 37g Radix Et Rhizoma Fagopyri Tatarici 36g
Radix Cyanotis vagae 36g Auricularia 34g Semen Ignatii 33g Herba Kalimeridis 33g
Fructus Choerospondiatis 31g Mirabilitum 30g Fructus Ligustri Lucidi 27g Folium camelliae assamicae 22g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of cerebroma, select the routine clinical observation of Patients with Brain Tumors 224 of making a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups at random, treatment group 112 examples, wherein male's 56 examples, women's 56 examples, 21～50 years old age, 35.5 years old mean age, average course of disease 2 years; Matched group 112 examples, wherein male's 56 examples, women's 56 examples, 20～51 years old age, 35.5 years old mean age, average course of disease 2 years.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), warm water delivery service after meal; Within 15 days, be 1 course for the treatment of, can fully recover 2～4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Matched group is taken E-646 sheet, is conventionally grown up one time 1 (E-646 50mg), and 3 times on the one, oral meal, visual age, symptom are taken the circumstances into consideration increase and decrease.
3, efficacy determination:
(1) cure: cardinal symptom all disappears, it is normal that brain recovers.
(2) effective: cardinal symptom obviously alleviates, brain takes a turn for the better to some extent.
(3) effective: cardinal symptom alleviates to some extent, and brain is clearly better.
(4) invalid: by treating rear cardinal symptom without alleviating or increasing the weight of.
4, result:
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, desolate certain, female, 22 years old, people from changzhou.Patient's head and neck portion pain, companion's vomiting when pain, headache is outbreak repeatedly, and companion's blurred vision, without diplopia.Afterwards because headache aggravation is shown in the capable CT examination of local hospital: left side volume top occupy-place.Go the wardrobe cranium MRI of tumour hospital further to check and be diagnosed as the pernicious glioma of volume top.Patient takes Chinese medicine preparation treatment of the present invention, take after 1 course for the treatment of, tumor is contracted to 3.5 × 1.9cm by 4.7 × 1.9cm, the diseases such as dizziness, headache, blurred vision are obviously improved, and continue to take after 3 courses for the treatment of nuclear magnetic resonance check, show that right side frontal lobe temporal lobe has no irregular abnormal strengthening shadow, have no displacement, brain stem, Cerebellar Morphology are as usual, the recurrence of following up a case by regular visits to that so far there are no.
2, journey, man, 37 years old, people from Wuhu.Patient is diagnosed as the cerebral glioma II phase, takes Chinese medicine preparation treatment of the present invention, takes after 1 course for the treatment of, through check, health takes a turn for the better to some extent, continues to take after 2 curative effects, review result shows, brain scans, blood routine examination is all no problem, and brain tumor can not be found substantially, health also has strength, recovery from illness, follows up a case by regular visits to and did not occur so far headache, dizzy phenomenon.
3, Yuan, female, 32 years old, people from inland river, Sichuan.Patient is diagnosed as cerebroma through hospital, hospital treatment many days, has no improvement, through taking Chinese medicine preparation treatment of the present invention, takes after 1 course for the treatment of, and symptom is alleviated to some extent, continue to take after 3 courses for the treatment of, and transference cure, recovery from illness, life is normal, follows up a case by regular visits to without recurrence after 1 year.
4, permitted certain, man, 50 years old, people from Hunan Huaihua.Patient's cerebral glioma IV level, performed the operation at that time, but had just recurred postoperative half a year; whole body is very itched, and sleeps also poor, and household worries very much; recommend by doctor, use Chinese medicine preparation treatment of the present invention, take after 2 courses for the treatment of; sleep and appetite have had improvement; just whole body is slightly itched in addition, takes after 4 courses for the treatment of, and skin pruritus symptom disappears; spirit complexion takes a turn for the better, under often can also oneself downstairs going to turn.
5, Shen, female, 44 years old, Pingliang, Gansu people.Patient suffers from cerebroma, uses multiple Drug therapy, does not feel any better, after do brain tumor enucleation, can soon recur, after being introduced, take Chinese medicine preparation treatment of the present invention, take after 1 course for the treatment of, symptom takes a turn for the better to some extent, continues to take after 2 courses for the treatment of transference cure, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.
6, Cao, man, 48 years old, people from Jilin songyuan.When checking, patient detects cerebroma, just taked chemotherapy, just started chemotherapy, patient is because of symptoms such as the weaker appearance vomitings of body constitution, in order to alleviate these symptoms, doctor gives patient and takes Chinese medicine preparation treatment of the present invention, takes after 1 course for the treatment of appetite, sleep relatively was all improved in the past, continue to take after 2 courses for the treatment of transference cure, recovery from illness.
Claims (5)
1. a Chinese medicine preparation for the treatment of cerebroma, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
35～57 parts of 35～59 parts of Herba Sonchi Oleracei of 36～60 parts of green starchs of 38～62 parts of Thallus Laminariae (Thallus Eckloniae)s of Herba Centellae
32～56 parts of 33～57 parts of Radix Et Rhizoma Fagopyri Tatarici of 33～57 parts of Folium Castaneae of 34～58 parts of Folium Raphani of Radix Wikstroemae
29～53 parts of 29～53 parts of Herba Kalimeridis of 30～54 parts of Semen Ignatii of 32～56 portions of Auricularias of Radix Cyanotis vagae
18～42 parts of 23～47 parts of Folium camelliae assamicaes of 26～50 parts of Fructus Ligustri Lucidi of 27～51 parts of Mirabilitum of Fructus Choerospondiatis.
2. a kind of Chinese medicine preparation for the treatment of cerebroma according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
39～55 parts of 39～55 parts of Herba Sonchi Oleracei of 40～56 parts of green starchs of 42～58 parts of Thallus Laminariae (Thallus Eckloniae)s of Herba Centellae
36～52 parts of 37～53 parts of Radix Et Rhizoma Fagopyri Tatarici of 37～53 parts of Folium Castaneae of 38～54 parts of Folium Raphani of Radix Wikstroemae
33～49 parts of 33～49 parts of Herba Kalimeridis of 34～50 parts of Semen Ignatii of 36～52 portions of Auricularias of Radix Cyanotis vagae
22～38 parts of 27～43 parts of Folium camelliae assamicaes of 30～46 parts of Fructus Ligustri Lucidi of 31～47 parts of Mirabilitum of Fructus Choerospondiatis.
3. a kind of Chinese medicine preparation for the treatment of cerebroma according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
43～51 parts of 43～51 parts of Herba Sonchi Oleracei of 44～52 parts of green starchs of 46～54 parts of Thallus Laminariae (Thallus Eckloniae)s of Herba Centellae
40～48 parts of 41～49 parts of Radix Et Rhizoma Fagopyri Tatarici of 41～49 parts of Folium Castaneae of 42～50 parts of Folium Raphani of Radix Wikstroemae
37～45 parts of 36～45 parts of Herba Kalimeridis of 38～46 parts of Semen Ignatii of 40～48 portions of Auricularias of Radix Cyanotis vagae
26～34 parts of 31～39 parts of Folium camelliae assamicaes of 34～42 parts of Fructus Ligustri Lucidi of 35～43 parts of Mirabilitum of Fructus Choerospondiatis.
4. a kind of Chinese medicine preparation for the treatment of cerebroma according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
47 parts of 47 parts of Herba Sonchi Oleracei of 48 parts of green starchs of 50 parts of Thallus Laminariae (Thallus Eckloniae)s of Herba Centellae
44 parts of 45 parts of Radix Et Rhizoma Fagopyri Tatarici of 45 parts of Folium Castaneae of 46 parts of Folium Raphani of Radix Wikstroemae
41 parts of 41 parts of Herba Kalimeridis of 42 parts of Semen Ignatii of 44 portions of Auricularias of Radix Cyanotis vagae
30 parts of 35 parts of Folium camelliae assamicaes of 38 parts of Fructus Ligustri Lucidi of 39 parts of Mirabilitum of Fructus Choerospondiatis.
5. a preparation method for the treatment of the Chinese medicine preparation of cerebroma as described in claim 1～4 any one, is characterized in that: comprise following processing step:
(1) Herba Centellae, Radix Et Rhizoma Fagopyri Tatarici and Fructus Choerospondiatis are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 DEG C of simmer down tos, relative density is 1.12～1.16 is for subsequent use;
(2) Thallus Laminariae (Thallus Eckloniae), Radix Wikstroemae, Folium Castaneae, Auricularia, Fructus Ligustri Lucidi and Folium camelliae assamicae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 DEG C, relative density is 1.10～1.13, for subsequent use;
(3) get the distilled water that green starch adds 3 times of amounts, heated and boiled also stirs, and makes it to reconcile into gluey gelatinized corn starch, for subsequent use;
(4) Herba Sonchi Oleracei, Folium Raphani and Herba Kalimeridis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) get Semen Ignatii decontamination, add water and mill as extract, for subsequent use;
(6) Radix Cyanotis vagae and Mirabilitum are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(7) above-mentioned steps (1)～(6) prepared thick paste, gluey gelatinized corn starch, juice, extract and fine powder are mixed, make capsule, obtain the Chinese medicine preparation for the treatment of cerebroma of the present invention.
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Application publication date: 20140723 |