CN105147809A - Traditional Chinese medicine composition treating wind-heat upper disturbing type supraorbital neuralgia - Google Patents

Traditional Chinese medicine composition treating wind-heat upper disturbing type supraorbital neuralgia Download PDF

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CN105147809A
CN105147809A CN201510598758.4A CN201510598758A CN105147809A CN 105147809 A CN105147809 A CN 105147809A CN 201510598758 A CN201510598758 A CN 201510598758A CN 105147809 A CN105147809 A CN 105147809A
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medicine composition
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wind
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董金兰
王树山
李斌
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Abstract

The invention discloses a traditional Chinese medicine composition treating wind-heat upper disturbing type supraorbital neuralgia. The traditional Chinese medicine composition is prepared from kamchatka bugbane rhizome, lysimachia capillipes hemsl, buta graveolens, wild clove roots, narrow-leaf angelica sinensis, trifoliate acanthopanax roots, achyranthes aspera, coffee senna, alpine cladonia and cryptotympana atrata fabricius. The traditional Chinese medicine composition treating wind-heat upper disturbing type supraorbital neuralgia has the advantages of being simple, convenient to use, cheap, good in effect and few in side effect. The traditional Chinese medicine composition treating wind-heat upper disturbing type supraorbital neuralgia is used for treating 60 patients (94 eyes), and the total effective rate is 96.81%. The traditional Chinese medicine composition treating wind-heat upper disturbing type supraorbital neuralgia is used for treating 60 patients (95 eyes) in a control group, and the total effective rate is 71.58%. The total effective rates of the two groups are compared, and the difference plays a role in statistics (P<0.05).

Description

A kind of Chinese medicine composition for the treatment of wind-heat troubling type supraorbital neuralgia
Technical field
The present invention relates to Chinese medicine sciemtifec and technical sphere, particularly a kind of Chinese medicine composition for the treatment of wind-heat troubling type supraorbital neuralgia.
Background technology
Supraorbital neuralgia is a kind of ophthalmology common disease.Supraorbital nerve is the end eventually that nervus frontalis is larger, and companion's supraorbital artery leaves eye socket by superior thyroid notch or supraorbital foramen.Be everlasting in socket of the eye and be divided into inside and outside, coincide each other again, in a quota, upper eyelid and conjunctiva, so supraorbital neuralgia is mainly at supraorbital margin.Because supraorbital nerve position place table is shallow, so have obvious tenderness at supraorbital notch place, being subject to exopathogen stimulates and falls ill.Clinical treatment often adopts the treatment such as vitamin B group, vasodilation, partial closure, and curative effect is undesirable, and side effect is more.Chinese medicine pain class pathological changes has simple and easy to do, few side effects and the advantage such as target spot is numerous.Wind-heat troubling type supraorbital neuralgia is supraorbital neuralgia different TCM syndrome types, report (the Ye Zuming of current accidental treatment by Chinese herbs supraorbital neuralgia, Su Jinrui, Ma Zhaorun. the routine observation of curative effect of Coryza Treated by Syndrome Differentiation supraorbital neuralgia 31. the Sichuan traditional Chinese medical science, 2009,27:111-112.), but do not add up separately the curative effect of wind-heat troubling type supraorbital neuralgia, therefore its therapeutic effect cannot be proved; Have no patent documentation and the specific product for the treatment of the type supraorbital neuralgia.Therefore analyse the traditional Chinese medical science pathogeny of wind-heat troubling type supraorbital neuralgia, the Chinese medicine composition of research and development treatment wind-heat troubling type supraorbital neuralgia has important clinical significance.The present inventor, to this has been conscientious research and verification experimental verification, achieves good therapeutic effect.
Summary of the invention
The object of the invention is to overcome in prior art the deficiency not having suitable and rational traditional Chinese medicine composition for treating scheme, namely provide one to treat wind-heat troubling type supraorbital neuralgia Chinese medicine composition.
In order to realize foregoing invention object, the invention provides following technical scheme:
Treat a Chinese medicine composition for wind-heat troubling type supraorbital neuralgia, be made up of the crude drug of following mass ratio:
Rhizoma cimicifugae simplicis 6 ~ 10 parts, Herba lysimachiae capillipedis 9 ~ 15 parts, Herba rutae 3 ~ 9 parts, Radix Luculiae intermediae 15 ~ 25 parts, Radix Angelicae seu Heraclei 8 ~ 12 parts, Radix Acanthopanacis Trifoliati 20 ~ 40 parts, Radix Achyranthis 9 ~ 15 parts, Herba cassiae occidentalis 6 ~ 10 parts, Cladonia alpestris (L.) Rabenh. 8 ~ 12 parts, cicada 3 ~ 9 parts.
Rhizoma cimicifugae simplicis: sweet, pungent, micro-hardship, to be slightly cold.Loose wind, removing toxic substances, yang invigorating, rash.Cure mainly seasonal epidemic pathogens epidemic disease, YANG MING headache, laryngalgia, macule, wind heat skin infection, chronic diarrhea proctoptosis, infantile measles.
Herba lysimachiae capillipedis: sweet, nontoxic, flat.Dispel the wind, promoting the circulation of QI to relieve pain, regulating menstruation.Cure mainly flu, cough, rheumatic arthralgia, abdominal distention, menoxenia, furuncle, venom.
Herba rutae: pungent, micro-hardship, cold.Expelling wind and clearing away heat, promoting blood circulation to remove blood stasis, subduing swelling and detoxicating.Cure mainly cold, fever, infantile hyperpyrexia infantile convulsion, dysmenorrhea, amenorrhea, traumatic injury, pathopyretic ulcer, infantile eczema, snake bite and insect sting.
Radix Luculiae intermediae: puckery, micro-hardship, cool.Promoting blood flow to regulate menstruation, anti-inflammatory analgetic.Cure mainly infantile hyperpyrexia stupor, laryngopharynx swelling and pain, menoxenia, dysmenorrhea, rheumatalgia, migraine, urinary tract infection, lithangiuria, general edema with yellowish skin is sick, has a headache after being ill, nervous, venom, trauma infection contamination.
Radix Angelicae seu Heraclei: dispel the wind and deliver, alleviating pain and detumescence.Cure mainly headche due to wind-cold, sinusitis, supraorbital bone pain, gingival swelling and pain, sore swollen toxin, hemorrhoid complicated by anal fistula is had blood in stool, cold-damp leucorrhea, burn.
Radix Acanthopanacis Trifoliati: bitter, pungent, cool.Heat-clearing and toxic substances removing, expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation.Cure mainly cold, fever, pharyngalgia, headache, cough chest pain, gastralgia, has loose bowels, dysentery, hypochondriac pain, jaundice, stranguria caused by urinary stone, leukorrhagia, rheumatic arthralgia, lumbago and skelalgia, and muscles and bones contracture is numb, injury and bone fracture, mumps, acute mastitis, sore swollen toxin, snake bite and insect sting.
Radix Achyranthis: sweet, micro-hardship, micro-acid, cold, returns liver, spleen channel.Blood circulation promoting and blood stasis dispelling, eliminating fire and detoxication, inducing diuresis for treating stranguria syndrome.Cure mainly amenorrhea, traumatic injury, rheumatic arthritis, dysentery, diphtheria, laryngopharynx swelling and pain, carbuncle sore, stranguria, edema.
Herba cassiae occidentalis: bitter, cold, mild toxicity.Respectful lung, liver heat removing, relieving constipation, removing toxic substances.Cure mainly cough and asthma, headache conjunctival congestion, urine stranguria with blood, constipation, carbuncle sore tumefacting virus, snake bite and insect sting.
Cladonia alpestris (L.) Rabenh.: light, flat.Suppressing the hyperactive liver improving eyesight, blood-arresting catamenia-regulating.Cure mainly wind-yang and up-boring, have a dizzy spell, migraine, order disease, epistaxis, menoxenia, leucorrhea.
Cicada: salty, sweet, cold, returns liver, lung meridian.Heat clearing away, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., relieving convulsion.Cure mainly infantile convulsion, epilepsy, night cry, migraine.
Supraorbital neuralgia motherland medical science is referred to as supraorbital bone pain, primary disease complicated mechanism, and wind-heat troubling type is many because attacking outside ailment said due to cold or exposure, follows and sun passages through which vital energy circulates disturbs order key and causes.Control suitable wind and heat dispersing, loose evil pain relieving.Rhizoma cimicifugae simplicis, Herba lysimachiae capillipedis, Herba rutae expelling wind and clearing away heat in the present invention, promoting the circulation of QI to relieve pain; Radix Luculiae intermediae, Radix Angelicae seu Heraclei dispel the wind and deliver, alleviating pain and detumescence; Radix Acanthopanacis Trifoliati, Radix Achyranthis blood circulation promoting and blood stasis dispelling, eliminating fire and detoxication; Herba cassiae occidentalis, the improving eyesight of Cladonia alpestris (L.) Rabenh. suppressing the hyperactive liver, respectful lung heat clearing away; Cicada relieves dizziness, high fever, infantile convulsions, epilepsy, etc. relieving convulsion.All medicines coordinate, and hit pathogenesis.
Preferably, the Chinese medicine composition of described treatment wind-heat troubling type supraorbital neuralgia is made up of the crude drug of following mass ratio:
Rhizoma cimicifugae simplicis 7 ~ 9 parts, Herba lysimachiae capillipedis 11 ~ 13 parts, Herba rutae 5 ~ 7 parts, Radix Luculiae intermediae 18 ~ 22 parts, Radix Angelicae seu Heraclei 9 ~ 11 parts, Radix Acanthopanacis Trifoliati 25 ~ 35 parts, Radix Achyranthis 11 ~ 13 parts, Herba cassiae occidentalis 7 ~ 9 parts, Cladonia alpestris (L.) Rabenh. 9 ~ 11 parts, cicada 5 ~ 7 parts.
Preferred further, the Chinese medicine composition of described treatment wind-heat troubling type supraorbital neuralgia is made up of the crude drug of following mass ratio:
Rhizoma cimicifugae simplicis 8 parts, Herba lysimachiae capillipedis 12 parts, Herba rutae 6 parts, Radix Luculiae intermediae 20 parts, Radix Angelicae seu Heraclei 10 parts, Radix Acanthopanacis Trifoliati 30 parts, Radix Achyranthis 12 parts, Herba cassiae occidentalis 8 parts, Cladonia alpestris (L.) Rabenh. 10 parts, cicada 6 parts.
The Chinese medicine composition of described treatment wind-heat troubling type supraorbital neuralgia can adopt existing Chinese medicine preparation technology to be prepared into any conventional oral preparations, such as can decocting be adopted to obtain water decoction said components, by other existing Chinese medicine preparation technology, the Chinese medicine composition of described treatment wind-heat troubling type supraorbital neuralgia can also be prepared into tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
Compared with prior art, beneficial effect of the present invention
The Chinese medicine composition for the treatment of wind-heat troubling type supraorbital neuralgia provided by the invention, treatment wind-heat troubling type supraorbital neuralgia have letter, just, honest and clean, test, the advantages such as few side effects.
This kind treats the Chinese medicine composition of wind-heat troubling type supraorbital neuralgia, and clinical efficacy is summed up
1 physical data
120 examples (189) patient is divided into matched group and treatment group at random.Matched group 60 example (95), male 19 example, women 41 example; 19 years old ~ 55 years old age, average 45.41 years old; Eyes 35 example, simple eye 25 examples; Companion's ametropia 31 example (52), companion's nasal sinusitis 11 example (13); Long-term near work 30 example (57).Treatment group 60 example (94), male 18 example, women 42 example; 19 years old ~ 55 years old age, average 45.14 years old; Eyes 34 example, simple eye 26 examples; Companion's ametropia 31 example (51), companion's nasal sinusitis 10 example (12); Long-term near work 32 example (60).Two groups of patients through statistical analysis no significant difference (P > 0.05), have comparability in age, sex, the course of disease etc.
2 diagnostic criterias
2.1 diagnostic criterias: reference " ophthalmology " (Ge Jianbian. ophthalmology. Beijing: People's Health Publisher, 2002.1) diagnostic criteria of supraorbital neuralgia in: break out, paroxysmal has an intense pain, pain is as electric shock sample, can betide in the nervi trigeminus distributed areas of side, supraorbital notch has obvious tenderness.Get rid of glaucoma, sinusitis, iridocyclitis, ametropia, orbital tumor and intracranial spaceoccupying lesion etc.
2.2 tcm syndrome classification: reference " Chinese medical disease Standardization of diagnosis and curative effect " (State Administration of Traditional Chinese Medicine. Chinese medical disease Standardization of diagnosis and curative effect. Nanjing: publishing house of Nanjing University, the syndrome-classification standard of supraorbital bone pain 1994:115.): wind-heat troubling type---superciliary ridge portion pain, nasal obstruction, fever of the body, aversion to wind.Red tongue, thin fur, floating and rapid pulse.
3 Therapeutic Method
Matched group is according to general hospital's routine prescription: oral mecobalamin dispersible tables 500mg, every day three times; Vitamin B complex tablet 20mg, every day three times.The oral following Chinese medicine composition for the treatment of group makes water decoction:
Rhizoma cimicifugae simplicis 8 grams, Herba lysimachiae capillipedis 12 grams, Herba rutae 6 grams, Radix Luculiae intermediae 20 grams, Radix Angelicae seu Heraclei 10 grams, Radix Acanthopanacis Trifoliati 30 grams, Radix Achyranthis 12 grams, Herba cassiae occidentalis 8 grams, Cladonia alpestris (L.) Rabenh. 10 grams, cicada 6 grams.Conveniently Chinese medicine preparation technology makes water decoction, everyone potion every day.
4 therapeutic outcomes
4.1 efficacy assessment standards: reference " Chinese medical disease Standardization of diagnosis and curative effect " (State Administration of Traditional Chinese Medicine. Chinese medical disease Standardization of diagnosis and curative effect. Nanjing: Nanjing University goes out society, the criterion of therapeutical effect of supraorbital bone pain 1994:115.): 1. cure: supraorbital bone pain disappears, without tenderness; 2. take a turn for the better: supraorbital bone pain alleviates, and tenderness alleviates; 3. do not heal: supraorbital bone pain and tenderness are all without improvement.
4.2 results: through treatment in 4 weeks, matched group cured 12, takes a turn for the better 56, did not heal 27, total effective rate 71.58%; Treatment group cures 76, takes a turn for the better 15, does not heal 3, total effective rate 96.81%.Two groups of total effective rates are compared, and difference has statistical significance (P < 0.05).
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is described in further detail.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following embodiment, all technology realized based on content of the present invention all belong to scope of the present invention.
Embodiment 1
A kind of Chinese medicine composition for the treatment of wind-heat troubling type supraorbital neuralgia, be by Rhizoma cimicifugae simplicis 10 grams, Herba lysimachiae capillipedis 15 grams, Herba rutae 9 grams, Radix Luculiae intermediae 25 grams, Radix Angelicae seu Heraclei 12 grams, Radix Acanthopanacis Trifoliati 40 grams, Radix Achyranthis 15 grams, Herba cassiae occidentalis 10 grams, Cladonia alpestris (L.) Rabenh. 12 grams, cicada 9 grams conveniently Chinese medicine preparation technology make water decoction, everyone potion every day.
Embodiment 2
A kind of Chinese medicine composition for the treatment of wind-heat troubling type supraorbital neuralgia, be by Rhizoma cimicifugae simplicis 9 grams, Herba lysimachiae capillipedis 13 grams, Herba rutae 7 grams, Radix Luculiae intermediae 22 grams, Radix Angelicae seu Heraclei 11 grams, Radix Acanthopanacis Trifoliati 35 grams, Radix Achyranthis 13 grams, Herba cassiae occidentalis 9 grams, Cladonia alpestris (L.) Rabenh. 11 grams, cicada 7 grams conveniently Chinese medicine preparation technology make water decoction, everyone potion every day.
Embodiment 3
A kind of Chinese medicine composition for the treatment of wind-heat troubling type supraorbital neuralgia, be by Rhizoma cimicifugae simplicis 8 grams, Herba lysimachiae capillipedis 12 grams, Herba rutae 6 grams, Radix Luculiae intermediae 20 grams, Radix Angelicae seu Heraclei 10 grams, Radix Acanthopanacis Trifoliati 30 grams, Radix Achyranthis 12 grams, Herba cassiae occidentalis 8 grams, Cladonia alpestris (L.) Rabenh. 10 grams, cicada 6 grams conveniently Chinese medicine preparation technology make water decoction, everyone potion every day.
Embodiment 4
A kind of Chinese medicine composition for the treatment of wind-heat troubling type supraorbital neuralgia, be by Rhizoma cimicifugae simplicis 7 grams, Herba lysimachiae capillipedis 11 grams, Herba rutae 5 grams, Radix Luculiae intermediae 18 grams, Radix Angelicae seu Heraclei 9 grams, Radix Acanthopanacis Trifoliati 25 grams, Radix Achyranthis 11 grams, Herba cassiae occidentalis 7 grams, Cladonia alpestris (L.) Rabenh. 9 grams, cicada 5 grams conveniently Chinese medicine preparation technology make water decoction, everyone potion every day.
Embodiment 5
A kind of Chinese medicine composition for the treatment of wind-heat troubling type supraorbital neuralgia, be by Rhizoma cimicifugae simplicis 6 grams, Herba lysimachiae capillipedis 9 grams, Herba rutae 3 grams, Radix Luculiae intermediae 15 grams, Radix Angelicae seu Heraclei 8 grams, Radix Acanthopanacis Trifoliati 20 grams, Radix Achyranthis 9 grams, Herba cassiae occidentalis 6 grams, Cladonia alpestris (L.) Rabenh. 8 grams, cicada 3 grams conveniently Chinese medicine preparation technology make water decoction, everyone potion every day.

Claims (4)

1. treat a Chinese medicine composition for wind-heat troubling type supraorbital neuralgia, it is characterized in that being made up of the crude drug of following mass ratio:
Rhizoma cimicifugae simplicis 6 ~ 10 parts, Herba lysimachiae capillipedis 9 ~ 15 parts, Herba rutae 3 ~ 9 parts, Radix Luculiae intermediae 15 ~ 25 parts, Radix Angelicae seu Heraclei 8 ~ 12 parts, Radix Acanthopanacis Trifoliati 20 ~ 40 parts, Radix Achyranthis 9 ~ 15 parts, Herba cassiae occidentalis 6 ~ 10 parts, Cladonia alpestris (L.) Rabenh. 8 ~ 12 parts, cicada 3 ~ 9 parts.
2. the Chinese medicine composition for the treatment of wind-heat troubling type supraorbital neuralgia as claimed in claim 1, is characterized in that being made up of the crude drug of following mass ratio:
Rhizoma cimicifugae simplicis 7 ~ 9 parts, Herba lysimachiae capillipedis 11 ~ 13 parts, Herba rutae 5 ~ 7 parts, Radix Luculiae intermediae 18 ~ 22 parts, Radix Angelicae seu Heraclei 9 ~ 11 parts, Radix Acanthopanacis Trifoliati 25 ~ 35 parts, Radix Achyranthis 11 ~ 13 parts, Herba cassiae occidentalis 7 ~ 9 parts, Cladonia alpestris (L.) Rabenh. 9 ~ 11 parts, cicada 5 ~ 7 parts.
3. the Chinese medicine composition for the treatment of wind-heat troubling type supraorbital neuralgia as claimed in claim 1, is characterized in that being made up of the crude drug of following mass ratio:
Rhizoma cimicifugae simplicis 8 parts, Herba lysimachiae capillipedis 12 parts, Herba rutae 6 parts, Radix Luculiae intermediae 20 parts, Radix Angelicae seu Heraclei 10 parts, Radix Acanthopanacis Trifoliati 30 parts, Radix Achyranthis 12 parts, Herba cassiae occidentalis 8 parts, Cladonia alpestris (L.) Rabenh. 10 parts, cicada 6 parts.
4. treat the preparation method of the Chinese medicine composition of wind-heat troubling type supraorbital neuralgia as claimed in claim 1, it is characterized in that the Chinese medicinal components of described mass ratio to be prepared into water decoction, tablet, water-honeyed pill, capsule, powder, unguentum, oral liquid, granule.
CN201510598758.4A 2015-09-18 2015-09-18 Traditional Chinese medicine composition treating wind-heat upper disturbing type supraorbital neuralgia Pending CN105147809A (en)

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CN103893488A (en) * 2014-04-19 2014-07-02 薛俊芳 Chinese medicine preparation for treating migraine and preparation method thereof

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