CN1879608A - 缓释的生物粘附口含片 - Google Patents

缓释的生物粘附口含片 Download PDF

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Publication number
CN1879608A
CN1879608A CNA2005101375941A CN200510137594A CN1879608A CN 1879608 A CN1879608 A CN 1879608A CN A2005101375941 A CNA2005101375941 A CN A2005101375941A CN 200510137594 A CN200510137594 A CN 200510137594A CN 1879608 A CN1879608 A CN 1879608A
Authority
CN
China
Prior art keywords
tablet
active component
testosterone
purposes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2005101375941A
Other languages
English (en)
Chinese (zh)
Inventor
威廉·J·博洛格纳
霍华德·L·莱维纳
菲利普·卡蒂埃
多米尼克·德齐格勒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Juniper Pharmaceuticals Inc
Original Assignee
Columbia Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22265404&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1879608(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Columbia Laboratories Inc filed Critical Columbia Laboratories Inc
Publication of CN1879608A publication Critical patent/CN1879608A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNA2005101375941A 1998-08-25 1999-08-24 缓释的生物粘附口含片 Pending CN1879608A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9784398P 1998-08-25 1998-08-25
US60/097,843 1998-08-25
US09/379,310 1999-08-23

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB998122009A Division CN1259903C (zh) 1998-08-25 1999-08-24 缓释的生物粘附口含片

Publications (1)

Publication Number Publication Date
CN1879608A true CN1879608A (zh) 2006-12-20

Family

ID=22265404

Family Applications (2)

Application Number Title Priority Date Filing Date
CNA2005101375941A Pending CN1879608A (zh) 1998-08-25 1999-08-24 缓释的生物粘附口含片
CNB998122009A Expired - Fee Related CN1259903C (zh) 1998-08-25 1999-08-24 缓释的生物粘附口含片

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNB998122009A Expired - Fee Related CN1259903C (zh) 1998-08-25 1999-08-24 缓释的生物粘附口含片

Country Status (25)

Country Link
US (1) US6248358B1 (https=)
EP (1) EP1105104B1 (https=)
JP (2) JP5411398B2 (https=)
KR (1) KR100716702B1 (https=)
CN (2) CN1879608A (https=)
AR (1) AR036972A1 (https=)
AT (1) ATE306253T1 (https=)
AU (1) AU754880B2 (https=)
BR (1) BR9913239B1 (https=)
CA (1) CA2341375C (https=)
DE (1) DE69927694T2 (https=)
DK (1) DK1105104T3 (https=)
ES (1) ES2251220T3 (https=)
HU (1) HU226591B1 (https=)
IL (1) IL141445A (https=)
MA (1) MA24964A1 (https=)
MX (1) MXPA01002007A (https=)
MY (2) MY125919A (https=)
NO (1) NO331255B1 (https=)
NZ (1) NZ509963A (https=)
PE (1) PE20001036A1 (https=)
RU (1) RU2227022C2 (https=)
UA (1) UA78967C2 (https=)
WO (1) WO2000010536A1 (https=)
ZA (1) ZA995445B (https=)

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JP2010248231A (ja) 2010-11-04
NO20010919D0 (no) 2001-02-23
WO2000010536A9 (en) 2000-08-24
BR9913239B1 (pt) 2010-11-16
MA24964A1 (fr) 2000-04-01
PE20001036A1 (es) 2000-10-12
KR20010072924A (ko) 2001-07-31
IL141445A0 (en) 2002-03-10
CN1259903C (zh) 2006-06-21
EP1105104B1 (en) 2005-10-12
NO20010919L (no) 2001-03-22
EP1105104A1 (en) 2001-06-13
US6248358B1 (en) 2001-06-19
MY125919A (en) 2006-08-30
HK1034895A1 (en) 2001-11-09
HUP0103218A2 (hu) 2001-12-28
DE69927694T2 (de) 2006-08-10
CA2341375C (en) 2006-07-11
ZA995445B (en) 2000-11-27
ES2251220T3 (es) 2006-04-16
MXPA01002007A (es) 2002-06-04
DK1105104T3 (da) 2006-02-06
BR9913239A (pt) 2001-05-15
MY133365A (en) 2007-11-30
JP2004500317A (ja) 2004-01-08
AU754880B2 (en) 2002-11-28
KR100716702B1 (ko) 2007-05-14
WO2000010536A1 (en) 2000-03-02
NO331255B1 (no) 2011-11-07
CA2341375A1 (en) 2000-03-02
CN1323201A (zh) 2001-11-21
HU226591B1 (en) 2009-04-28
WO2000010536A8 (en) 2000-06-15
IL141445A (en) 2005-12-18
RU2227022C2 (ru) 2004-04-20
AR036972A1 (es) 2004-10-20
AU5582699A (en) 2000-03-14
JP5411398B2 (ja) 2014-02-12
DE69927694D1 (de) 2005-11-17
NZ509963A (en) 2004-11-26

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