CN1833700A - Medicinal compsns. for treating rheumatism and rheumatoid arthritis and its prepn. method - Google Patents
Medicinal compsns. for treating rheumatism and rheumatoid arthritis and its prepn. method Download PDFInfo
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- CN1833700A CN1833700A CN 200510055266 CN200510055266A CN1833700A CN 1833700 A CN1833700 A CN 1833700A CN 200510055266 CN200510055266 CN 200510055266 CN 200510055266 A CN200510055266 A CN 200510055266A CN 1833700 A CN1833700 A CN 1833700A
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Abstract
A Chinese medicine for treating rheumatic and rheumatoid arthritis, periomethritis, general pain, etc is prepared from 25 Chinese-medicinal materials including centipede, black ant. Sichuan aconite root, Chuan-xiong rhizome, etc. Its preparing process is also disclosed.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition for the treatment of rheumatism atrophic arthritis and preparation method thereof.
Background technology
Rheumatism is that a kind of common clinical, frequently-occurring disease, disease cycle are longer, and the clinical symptoms performance is various, the stubborn disease that the treatment phase is long.Because of such disease cause of disease, pathogenesis more complicated, clinical be marginality, multidisciplinary performance more, the limitation of Chinese medicine itself and to the heterogeneity of the understanding of this type of disease is in addition all controlled and the clinical research work of such pathological changes is brought certain difficulty to clinical dialectical executing.In motherland's medical science, rheumatism is collectively referred to as " numbness " disease.A Plain Questions of Huangdi's Internal Classic numbness opinion piece of writing the 43 is said: " wind, cold, wet three gas are assorted extremely, close and be numbness also ".Domination of wind then is a migratory arthralgia, and domination of cold then is an arthralgia aggravated by cold, and domination of damp pathogen then is an arthralgia caused mainly by damp.That this disease Therapeutic Principle dispels the wind, wins is wet, warming the meridian, by cold, make wind, cold, wet three gas are dispeled and disease is separated.
Technology contents
The object of the invention is to provide a kind of pharmaceutical composition that the treatment rheumatism atrophic arthritis is had remarkable result.
Another object of the present invention is to provide a kind of treatment rheumatism atrophic arthritis preparation of drug combination method.
The present invention is achieved through the following technical solutions: choose crude drug
Semen Strychni 30-80 weight portion Cortex Acanthopancis 15-200 weight portion Radix Clematidis 15-100 weight portion
Radix Saposhnikoviae 15-100 weight portion Radix Achyranthis Bidentatae 15-200 weight portion Rhizoma Cibotii 15-200 weight portion
Scorpio 10-50 weight portion Scolopendra 5-10 weight portion Squama Manis 10-50 weight portion
Formica fusca 10-100 weight portion Radix Aconiti 20-100 weight portion Herba Epimedii 15-60 weight portion
Cortex erythrinae 10-50 weight portion Radix Angelicae Pubescentis 15-60 weight portion Herba Aristolochiae Mollissimae 15-100 weight portion
Herba Siegesbeckiae 20-100 weight portion Os Canitis 10-200 weight portion Rhizoma Drynariae 15-200 weight portion
Rhizoma Chuanxiong 15-100 weight portion Radix Dipsaci 15-200 weight portion Rhizoma Corydalis 15-100 weight portion
Olibanum 15-100 weight portion Radix Angelicae Dahuricae 15-100 weight portion Rhizoma Homalomenae 20-200 weight portion
Herba Taxilli 15-200 weight portion
Optimum ratio of the present invention is:
Semen Strychni 30 weight portion Cortex Acanthopanciss 15 weight portion Radix Clematidis 15 weight portions
Radix Saposhnikoviae 15 weight portion Radix Achyranthis Bidentataes 15 weight portion Rhizoma Cibotii 15 weight portions
Scorpio 10-50 weight portion Scolopendra 5 weight portion Squama Maniss 10 weight portions
Formica fusca 10 weight portion Radix Aconitis 20 weight portion Herba Epimedii 15 weight portions
Cortex erythrinae 10 weight portion Radix Angelicae Pubescentiss 15 weight portion Herba Aristolochiae Mollissimaes 15 weight portions
Herba Siegesbeckiae 20 weight portion Os Canitis 10 weight portion Rhizoma Drynariae 15 weight portions
Rhizoma Chuanxiong 15 weight portion Radix Dipsacis 15 weight portion Rhizoma Corydalis 15 weight portions
The Olibanum 15 weight portion Radixs Angelicae Dahuricae 15 weight portion Rhizoma Homalomenaes 20 weight portions
Herba Taxilli 15 weight portions
Another optimum ratio of the present invention is:
Semen Strychni 80 weight portion Cortex Acanthopanciss 200 weight portion Radix Clematidis 100 weight portions
Radix Saposhnikoviae 100 weight portion Radix Achyranthis Bidentataes 200 weight portion Rhizoma Cibotii 200 weight portions
Scorpio 50 weight portion Scolopendras 10 weight portion Squama Maniss 50 weight portions
Formica fusca 100 weight portion Radix Aconitis 100 weight portion Herba Epimedii 60 weight portions
Cortex erythrinae 50 weight portion Radix Angelicae Pubescentiss 60 weight portion Herba Aristolochiae Mollissimaes 100 weight portions
Herba Siegesbeckiae 100 weight portion Os Canitis 200 weight portion Rhizoma Drynariae 200 weight portions
Rhizoma Chuanxiong 100 weight portion Radix Dipsacis 200 weight portion Rhizoma Corydalis 100 weight portions
The Olibanum 100 weight portion Radixs Angelicae Dahuricae 100 weight portion Rhizoma Homalomenaes 200 weight portions
Herba Taxilli 200 weight portions
Preparation method of the present invention is to yellow unhairing with the Semen Strychni stir-baking with sand; The Cortex Acanthopancis parch; Radix Clematidis is mixed thoroughly with 3-20 parts by volume yellow wine, and is vexed at the pot internal heating, and low baking temperature is fried and done; Radix Achyranthis Bidentatae adds water 3-40 parts by volume with 0.38-5 weight portion salt to be mixed thoroughly, runs through in pot, and low baking temperature is vexed to be done; The Rhizoma Cibotii section to heaving, is taken out unhairing with stir-baking with sand; Scorpio adds 4-20 parts by volume water logging bubble 8-16 hour with 0.6-3 weight portion salt, with slow fire decocting in water is done and is taken out airing; Scolopendra is yellow with the slow fire roasting; Squama Manis dips in airing with stir-baking with sand while hot in vinegar after heaving; The Formica fusca parching to brown; Radix Aconiti is steamed or boiled 6-7 hour; Airing after 10-30 minute is steamed in the Herba Siegesbeckiae chopping in pot; Os Canitis with stir-baking with sand to buff; The Rhizoma Drynariae yellow unhairing of stir-baking with sand; The Rhizoma Chuanxiong section adds 2.25-15 parts by volume yellow wine mixes thoroughly, vexed slightly, and slow fire is fried to yellow; Radix Dipsaci adds 1.13-15 parts by volume yellow wine to be mixed thoroughly, and vexed slightly back slow fire is fried to dusky; Rhizoma Corydalis is pulverized and is mixed thoroughly with 2.25-15 parts by volume vinegar, and slow fire was fried 5-10 minute; Olibanum is pulverized and mixed thoroughly with 1.5-10 parts by volume vinegar, and is vexed slightly, and slow fire was fried 5-10 minute; Above-mentioned all raw material medicated powder are become fine powder, cross the 80-100 mesh sieve, make clinical acceptable tablet, capsule or granule.
Weight portion/parts by volume of the present invention is that g/ml is corresponding.
Another preparation method of the present invention is that the medicinal 1000-10000 parts by volume of above-mentioned raw materials Oleum Sesami was soaked 3-5 days, boil with high heat, become withered and yellow black and be advisable by sallow, changing slow fire then into endures slowly, endure to dripping into pearl and filter medicinal residues, taking liquid still boils with slow fire in pot, generally endure to the time about 1-2 hour, the cold water of promptly not stopping using drips medicine inspection to be tested, it is broken being as the criterion that plaster flicks, can be under fire 180-1800 weight portion Plumbum preparatium, can be red down several times, and ceaselessly stir, following pellet should not be too fast, also unsuitable excessive, treat to can be made into when plaster is black emplastrum.
The conventional adjuvant that pharmaceutical composition of the present invention adds is pharmaceutically made clinical acceptable forms, as in tablet, suppository, capsule, granule, spray, ointment, emplastrum or the ointment any.
Pharmaceutical composition of the present invention has effects such as expelling wind and removing dampness, promoting the flow of QI in the collateral by warming the meridian, bone and muscle strengthening, promoting blood circulation and stopping pain, and is remarkable to effects such as treatment rheumatism, rheumatoid, scapulohumeral periarthritis, numb limbs and tense tendons, general aching, has no side effect.
Following experimental example is used to further specify the present invention:
1, clinical data
In clinical treatment 80 examples, male 45 examples, women 35 examples.20 examples below 40 years old, 60 examples more than 40 years old.Rheumatic arthritis 22 examples wherein, rheumatoid arthritis 3, scapulohumeral periarthritis 15 examples, cervical spondylosis 10 examples, lumbar spondylosis, hyperosteogeny, outstanding totally 15 examples, sciatica 15 examples.
2, Therapeutic Method
2.1 strong muscle, bone, promoting blood circulation and stopping pain the present invention's " numbness effect health " capsule for oral administration, one day 3 times, each 3-4 grain, be 15 days 1 course of treatment.
2.2 expelling wind and removing dampness, promoting the flow of QI in the collateral by warming the meridian external application the present invention " numbness effect health ", with pain spot or corresponding point-application, one pasted 7 days, and paste a course of treatment 2.
3, criterion of therapeutical effect
Cure: through 1-3 the course of treatment Comprehensive Treatment, symptoms such as local pain, swelling, stiff, numbness all disappear.
Produce effects: through 1-3 course of therapy, sx or basic disappearances such as pain, swelling, stiff, numbness.
Effectively: through 1-3 course of therapy, symptom such as pain, swelling, stiff, numbness alleviates to some extent, and function also makes moderate progress.
Invalid: through 1-3 course of therapy, symptom function such as pain, swelling, stiff, numbness does not have improvement.
4, therapeutic outcome
In clinical treatment 80 examples, rheumatic arthritis 22 examples are cured 15 examples, produce effects 7 examples; Rheumatoid arthritis 3 examples, produce effects 1 example, effective 2 examples; Scapulohumeral periarthritis 15 examples are cured 8 examples, produce effects 7 examples; Cervical spondylosis 10 examples are cured 3 examples, produce effects 7 examples; Lumbar spondylosis, hyperosteogeny, outstanding totally 15 examples are cured 3 examples, produce effects 5 examples, effective 7 examples; Sciatica 15 examples are cured 6 examples, produce effects 5 examples, effective 4 examples.
Above-mentioned Comprehensive Treatment result, 80 examples are cured 35 examples, produce effects 32 examples, effective 13 examples, invalid 0 example, total effective rate is 100%.
Following embodiment is used to further specify the present invention:
Embodiment 1: the preparation of capsule
Semen Strychni 80g Cortex Acanthopancis 200g Radix Clematidis 100g Radix Saposhnikoviae 100g
Radix Achyranthis Bidentatae 200g Rhizoma Cibotii 200g Scorpio 50g Scolopendra 10g
Squama Manis 50g Formica fusca 100g Radix Aconiti 100g Herba Epimedii 60g
Cortex erythrinae 50g Radix Angelicae Pubescentis 60g Herba Aristolochiae Mollissimae 100g Herba Siegesbeckiae 100g
Os Canitis 200g Rhizoma Drynariae 200g Rhizoma Chuanxiong 100g Radix Dipsaci 200g
Rhizoma Corydalis 100g Olibanum 100g Radix Angelicae Dahuricae 100g Rhizoma Homalomenae 200g
Herba Taxilli 200g
With the Semen Strychni stir-baking with sand to yellow unhairing; The Cortex Acanthopancis parch; Radix Clematidis is mixed thoroughly with the 20ml yellow wine, and is vexed at the pot internal heating, and low baking temperature is fried and done; Radix Achyranthis Bidentatae adds water 40ml with 5g salt to be mixed thoroughly, runs through in pot, and low baking temperature is vexed to be done; The Rhizoma Cibotii section to heaving, is taken out unhairing with stir-baking with sand; Scorpio adds 20ml water logging bubble 12 hours with 3g salt, with slow fire decocting in water is done and is taken out airing; Scolopendra is yellow with the slow fire roasting; Squama Manis dips in airing with stir-baking with sand while hot in vinegar after heaving; The Formica fusca parching to brown; Radix Aconiti was steamed 7 hours; Airing after 20 minutes is steamed in the Herba Siegesbeckiae chopping in pot; Os Canitis with sand to buff; The Rhizoma Drynariae yellow unhairing of stir-baking with sand; The Rhizoma Chuanxiong section adds the 15ml yellow wine mixes thoroughly, vexed slightly, and slow fire is fried to yellow; Radix Dipsaci adds the 15ml yellow wine to be mixed thoroughly, and vexed slightly back slow fire is fried to dusky; Rhizoma Corydalis is pulverized and is mixed thoroughly with 15ml vinegar, and slow fire was fried 10 minutes; Olibanum is pulverized and mixed thoroughly with 10ml vinegar, and is vexed slightly, and slow fire was fried 10 minutes; Above-mentioned all raw material medicated powder are become fine powder, cross 100 mesh sieves, adorn capsule No. 0, every day two to three times, each three to four, taking medicine after meal, 15 days per courses of treatment.
Embodiment 2: the preparation of capsule
Semen Strychni 50g Cortex Acanthopancis 100g Radix Clematidis 70g Radix Saposhnikoviae 70g
Radix Achyranthis Bidentatae 100g Rhizoma Cibotii 100g Scorpio 30g Scolopendra 8g
Squama Manis 30g Formica fusca 60g Radix Aconiti 60g Herba Epimedii 40g
Cortex erythrinae 30g Radix Angelicae Pubescentis 40g Herba Aristolochiae Mollissimae 60g Herba Siegesbeckiae 70g
Os Canitis 100g Rhizoma Drynariae 100g Rhizoma Chuanxiong 70g Radix Dipsaci 100g
Rhizoma Corydalis 70g Olibanum 70g Radix Angelicae Dahuricae 70g Rhizoma Homalomenae 100g
Herba Taxilli 100g
With the Semen Strychni stir-baking with sand to yellow unhairing; The Cortex Acanthopancis parch; Radix Clematidis is mixed thoroughly with the 15ml yellow wine, and is vexed at the pot internal heating, and low baking temperature is fried and done; Radix Achyranthis Bidentatae adds water 20ml with 2.5g salt to be mixed thoroughly, runs through in pot, and low baking temperature is vexed to be done; The Rhizoma Cibotii section to heaving, is taken out unhairing with stir-baking with sand; Scorpio adds 12ml water logging bubble 12 hours with 1.8g salt, with slow fire decocting in water is done and is taken out airing; Scolopendra is yellow with the slow fire roasting; Squama Manis dips in airing with stir-baking with sand while hot in vinegar after heaving; The Formica fusca parching to brown; Radix Aconiti was boiled 6 hours; Airing after 20 minutes is steamed in the Herba Siegesbeckiae chopping in pot; Os Canitis with sand to buff; The Rhizoma Drynariae yellow unhairing of stir-baking with sand; The Rhizoma Chuanxiong section adds the 10ml yellow wine mixes thoroughly, vexed slightly, and slow fire is fried to yellow; Radix Dipsaci adds the 7.5ml yellow wine to be mixed thoroughly, and vexed slightly back slow fire is fried to dusky; Rhizoma Corydalis is pulverized and is mixed thoroughly with 10ml vinegar, and slow fire was fried 8 minutes; Olibanum is pulverized and mixed thoroughly with 7ml vinegar, and is vexed slightly, and slow fire was fried 8 minutes; Above-mentioned all raw material medicated powder are become fine powder, cross 100 sieves, adorn capsule No. 0.Every day two to three times, each three to four, taking medicine after meal, 15 days per courses of treatment.
Embodiment 3: the preparation of tablet
Semen Strychni 40g Cortex Acanthopancis 160g Radix Clematidis 30g Radix Saposhnikoviae 80g
Radix Achyranthis Bidentatae 50g Rhizoma Cibotii 160g Scorpio 20g Scolopendra 8g
Squama Manis 20g Formica fusca 80g Radix Aconiti 40g Herba Epimedii 50g
Cortex erythrinae 20g Radix Angelicae Pubescentis 50g Herba Aristolochiae Mollissimae 80g Herba Siegesbeckiae 40g
Os Canitis 160g Rhizoma Drynariae 50g Rhizoma Chuanxiong 80g Radix Dipsaci 50g
Rhizoma Corydalis 80g Olibanum 30g Radix Angelicae Dahuricae 80g Rhizoma Homalomenae 50g
Herba Taxilli 160g
With the Semen Strychni stir-baking with sand to yellow unhairing; The Cortex Acanthopancis parch; Radix Clematidis is mixed thoroughly with the 6ml yellow wine, and is vexed at the pot internal heating, and low baking temperature is fried and done; Radix Achyranthis Bidentatae adds water 10ml with 1.25g salt to be mixed thoroughly, runs through in pot, and low baking temperature is vexed to be done; The Rhizoma Cibotii section to heaving, is taken out unhairing with stir-baking with sand; Scorpio adds 7ml water logging bubble 10 hours with 1g salt, with slow fire decocting in water is done and is taken out airing; Scolopendra is yellow with the slow fire roasting; Squama Manis dips in airing with stir-baking with sand while hot in vinegar after heaving; The Formica fusca parching to brown; Radix Aconiti was steamed 6.5 hours; Airing after 15 minutes is steamed in the Herba Siegesbeckiae chopping in pot; Os Canitis with sand to buff; The Rhizoma Drynariae yellow unhairing of stir-baking with sand; The Rhizoma Chuanxiong section adds the 12ml yellow wine mixes thoroughly, vexed slightly, and slow fire is fried to yellow; Radix Dipsaci adds the 4ml yellow wine to be mixed thoroughly, and vexed slightly back slow fire is fried to dusky; Rhizoma Corydalis is pulverized and is mixed thoroughly with 12ml vinegar, and slow fire was fried 8 minutes; Olibanum is pulverized and mixed thoroughly with 3ml vinegar, and is vexed slightly, and slow fire was fried 6 minutes; Above-mentioned all raw material medicated powder are become fine powder, cross 100 mesh sieves, make tablet.
Embodiment 4: the preparation of granule
Semen Strychni 60g Cortex Acanthopancis 50g Radix Clematidis 80g Radix Saposhnikoviae 30g
Radix Achyranthis Bidentatae 160g Rhizoma Cibotii 50g Scorpio 40g Scolopendra 10g
Squama Manis 40g Formica fusca 30g Radix Aconiti 160g Herba Epimedii 30g
Cortex erythrinae 40g Radix Angelicae Pubescentis 30g Herba Aristolochiae Mollissimae 30g Herba Siegesbeckiae 80g
Os Canitis 50g Rhizoma Drynariae 160g Rhizoma Chuanxiong 30g Radix Dipsaci 160g
Rhizoma Corydalis 30g Olibanum 80g Radix Angelicae Dahuricae 30g Rhizoma Homalomenae 160g
Herba Taxilli 50g
With the Semen Strychni stir-baking with sand to yellow unhairing; The Cortex Acanthopancis parch; Radix Clematidis is mixed thoroughly with the 16ml yellow wine, and is vexed at the pot internal heating, and low baking temperature is fried and done; Radix Achyranthis Bidentatae adds water 30ml with 4g salt to be mixed thoroughly, runs through in pot, and low baking temperature is vexed to be done; The Rhizoma Cibotii section to heaving, is taken out unhairing with stir-baking with sand; Scorpio adds 15ml water logging bubble 14 hours with 2g salt, with slow fire decocting in water is done and is taken out airing; Scolopendra is yellow with the slow fire roasting; The Formica fusca parching to brown; Radix Aconiti was boiled 6.5 hours; Squama Manis dips in airing with stir-baking with sand while hot in vinegar after heaving; Airing after 25 minutes is steamed in the Herba Siegesbeckiae chopping in pot; Os Canitis with sand to buff; The Rhizoma Drynariae yellow unhairing of stir-baking with sand; The Rhizoma Chuanxiong section adds the 5ml yellow wine mixes thoroughly, vexed slightly, and slow fire is fried to yellow; Radix Dipsaci adds the 12ml yellow wine to be mixed thoroughly, and vexed slightly back slow fire is fried to dusky; Rhizoma Corydalis is pulverized and is mixed thoroughly with 5ml vinegar, and slow fire was fried 6 minutes; Olibanum is pulverized and mixed thoroughly with 8ml vinegar, and is vexed slightly, and slow fire was fried 8 minutes; Above-mentioned all raw material medicated powder are become fine powder, cross 80 mesh sieves, make granule.
Embodiment 5: the preparation of emplastrum
Semen Strychni 30g Cortex Acanthopancis 15g Radix Clematidis 15g Radix Saposhnikoviae 15g
Radix Achyranthis Bidentatae 15g Rhizoma Cibotii 15g Scorpio 10g Scolopendra 10g
Squama Manis 10g Formica fusca 10g Radix Aconiti 20g Herba Epimedii 15g
Cortex erythrinae 10g Radix Angelicae Pubescentis 15g Herba Aristolochiae Mollissimae 15g Herba Siegesbeckiae 20g
Os Canitis 10g Rhizoma Drynariae 15g Rhizoma Chuanxiong 15g Radix Dipsaci 15g
Rhizoma Corydalis 15g Olibanum 15g Radix Angelicae Dahuricae 15g Rhizoma Homalomenae 20g
Herba Taxilli 15g
The medicinal 1000ml Oleum Sesami of above-mentioned raw materials was soaked 3 days, boil with high heat, become withered and yellow black and be advisable by sallow, change slow fire then into and endure slowly, endure to dripping into pearl and filter medicinal residues, taking liquid still boils with slow fire in pot, the cold water of promptly not stopping using drips medicine inspection to be tested, and it is broken being as the criterion that plaster flicks, and the time that generally boils is about 1-2 hour, 180g Plumbum preparatium under fire, can be red down several times, and ceaselessly stir, following pellet should not be too fast, also unsuitable excessive, treat to make when plaster is black emplastrum.With pain spot or corresponding point-application, one pasted 7 days, and paste a course of treatment 2.
Claims (10)
1, a kind of pharmaceutical composition for the treatment of rheumatism atrophic arthritis is characterized in that said composition is to be made by following crude drug:
Semen Strychni 30-80 weight portion Cortex Acanthopancis 15-200 weight portion Radix Clematidis 15-100 weight portion
Radix Saposhnikoviae 15-100 weight portion Radix Achyranthis Bidentatae 15-200 weight portion Rhizoma Cibotii 15-200 weight portion
Scorpio 10-50 weight portion Scolopendra 5-10 weight portion Squama Manis 10-50 weight portion
Formica fusca 10-100 weight portion Radix Aconiti 20-100 weight portion Herba Epimedii 15-60 weight portion
Cortex erythrinae 10-50 weight portion Radix Angelicae Pubescentis 15-60 weight portion Herba Aristolochiae Mollissimae 15-100 weight portion
Herba Siegesbeckiae 20-100 weight portion Os Canitis 10-200 weight portion Rhizoma Drynariae 15-200 weight portion
Rhizoma Chuanxiong 15-100 weight portion Radix Dipsaci 15-200 weight portion Rhizoma Corydalis 15-100 weight portion
Olibanum 15-100 weight portion Radix Angelicae Dahuricae 15-100 weight portion Rhizoma Homalomenae 20-200 weight portion
Herba Taxilli 15-200 weight portion.
2, a kind of pharmaceutical composition for the treatment of rheumatism atrophic arthritis according to claim 1 is characterized in that said composition is to be made by following crude drug:
Semen Strychni 50 weight portion Cortex Acanthopanciss 100 weight portion Radix Clematidis 70 weight portions
Radix Saposhnikoviae 70 weight portion Radix Achyranthis Bidentataes 100 weight portion Rhizoma Cibotii 100 weight portions
Scorpio 30 weight portion Scolopendras 8 weight portion Squama Maniss 30 weight portions
Formica fusca 60 weight portion Radix Aconitis 60 weight portion Herba Epimedii 40 weight portions
Cortex erythrinae 30 weight portion Radix Angelicae Pubescentiss 40 weight portion Herba Aristolochiae Mollissimaes 60 weight portions
Herba Siegesbeckiae 70 weight portion Os Canitis 100 weight portion Rhizoma Drynariae 100 weight portions
Rhizoma Chuanxiong 70 weight portion Radix Dipsacis 100 weight portion Rhizoma Corydalis 70 weight portions
The Olibanum 70 weight portion Radixs Angelicae Dahuricae 70 weight portion Rhizoma Homalomenaes 100 weight portions
Herba Taxilli 100 weight portions.
3, a kind of pharmaceutical composition for the treatment of rheumatism atrophic arthritis according to claim 1 is characterized in that said composition is to be made by following crude drug:
Semen Strychni 40 weight portion Cortex Acanthopanciss 160 weight portion Radix Clematidis 30 weight portions
Radix Saposhnikoviae 80 weight portion Radix Achyranthis Bidentataes 50 weight portion Rhizoma Cibotii 160 weight portions
Scorpio 20 weight portion Scolopendras 8 weight portion Squama Maniss 20 weight portions
Formica fusca 80 weight portion Radix Aconitis 40 weight portion Herba Epimedii 50 weight portions
Cortex erythrinae 20 weight portion Radix Angelicae Pubescentiss 50 weight portion Herba Aristolochiae Mollissimaes 80 weight portions
Herba Siegesbeckiae 40 weight portion Os Canitis 160 weight portion Rhizoma Drynariae 50 weight portions
Rhizoma Chuanxiong 80 weight portion Radix Dipsacis 50 weight portion Rhizoma Corydalis 80 weight portions
The Olibanum 30 weight portion Radixs Angelicae Dahuricae 80 weight portion Rhizoma Homalomenaes 50 weight portions
Herba Taxilli 160 weight portions.
4,, it is characterized in that the conventional adjuvant that said composition adds pharmaceutically makes the dosage form of clinical acceptance according to claim 1 or 2 or 3 described a kind of pharmaceutical compositions for the treatment of rheumatism atrophic arthritis.
5, a kind of pharmaceutical composition for the treatment of rheumatism atrophic arthritis according to claim 4 is characterized in that the dosage form that the said composition thing is made is tablet, suppository, capsule, granule, spray, ointment, emplastrum or ointment.
6, according to claim 1 or 2 or 3 described a kind of pharmaceutical compositions for the treatment of rheumatism atrophic arthritis, it is characterized in that the preparation method of said composition is: with the Semen Strychni stir-baking with sand to yellow unhairing; The Cortex Acanthopancis parch; Radix Clematidis is mixed thoroughly with 3-20 parts by volume yellow wine, and is vexed at the pot internal heating, and low baking temperature is fried and done; Radix Achyranthis Bidentatae adds water 3-40 parts by volume with 0.38-5 weight portion salt to be mixed thoroughly, runs through in pot, and low baking temperature is vexed to be done; The Rhizoma Cibotii section to heaving, is taken out unhairing with stir-baking with sand; Scorpio adds 4-20 parts by volume water logging bubble 8-16 hour with 0.6-3 weight portion salt, with slow fire decocting in water is done and is taken out airing; Scolopendra is yellow with the slow fire roasting; Squama Manis dips in airing with stir-baking with sand while hot in vinegar after heaving; The Formica fusca parching to brown; Radix Aconiti is steamed or boiled 6-7 hour; Airing after 10-30 minute is steamed in the Herba Siegesbeckiae chopping in pot; Os Canitis with stir-baking with sand to buff; The Rhizoma Drynariae yellow unhairing of stir-baking with sand; The Rhizoma Chuanxiong section adds 2.25-15 parts by volume yellow wine mixes thoroughly, vexed slightly, and slow fire is fried to yellow; Radix Dipsaci adds 1.13-15 parts by volume yellow wine to be mixed thoroughly, and vexed slightly back slow fire is fried to dusky; Rhizoma Corydalis is pulverized and is mixed thoroughly with 2.25-15 parts by volume vinegar, and slow fire was fried 5-10 minute; Olibanum is pulverized and mixed thoroughly with 1.5-10 parts by volume vinegar, and is vexed slightly, and slow fire was fried 5-10 minute; Above-mentioned all raw material medicated powder are become fine powder, cross the 80-100 mesh sieve, make clinical acceptable tablet, capsule or granule.
7, preparation of drug combination method according to claim 6 is characterized in that this preparation method is: with the Semen Strychni stir-baking with sand to yellow unhairing; The Cortex Acanthopancis parch; Radix Clematidis is mixed thoroughly with 20 parts by volume yellow wine, and is vexed at the pot internal heating, and low baking temperature is fried and done; Radix Achyranthis Bidentatae adds water 40 parts by volume with 5 weight portion salt to be mixed thoroughly, runs through in pot, and low baking temperature is vexed to be done; The Rhizoma Cibotii section to heaving, is taken out unhairing with stir-baking with sand; Scorpio adds 20 parts by volume water loggings bubble 12 hours with 3 weight portion salt, with slow fire decocting in water is done and is taken out airing; Scolopendra is yellow with the slow fire roasting; Squama Manis dips in airing with stir-baking with sand while hot in vinegar after heaving; The Formica fusca parching to brown; Radix Aconiti was steamed 6-7 hour; Airing after 20 minutes is steamed in the Herba Siegesbeckiae chopping in pot; Os Canitis with stir-baking with sand to buff; The Rhizoma Drynariae yellow unhairing of stir-baking with sand; The Rhizoma Chuanxiong section adds 15 parts by volume yellow wine mixes thoroughly, vexed slightly, and slow fire is fried to yellow; Radix Dipsaci adds 15 parts by volume yellow wine to be mixed thoroughly, and vexed slightly back slow fire is fried to dusky; Rhizoma Corydalis is pulverized and is mixed thoroughly with 15 parts by volume vinegar, and slow fire was fried 10 minutes; Olibanum is pulverized and mixed thoroughly with 10 parts by volume vinegar, and is vexed slightly, and slow fire was fried 10 minutes; Above-mentioned all raw material medicated powder are become fine powder, cross 100 mesh sieves, make tablet, capsule or the granule of clinical acceptance.
8, according to claim 1 or 2 or 3 described a kind of pharmaceutical compositions for the treatment of rheumatism atrophic arthritis, the preparation method that it is characterized in that said composition is: the medicinal 1000-10000 parts by volume of above-mentioned raw materials Oleum Sesami was soaked 3-5 days, boil with high heat, become withered and yellow black and be advisable by sallow, changing slow fire then into endures slowly, endure to dripping into pearl and filter medicinal residues, taking liquid still boils with slow fire in pot, generally endure to the time about 1-2 hour, the cold water of promptly not stopping using drips medicine inspection to be tested, it is broken being as the criterion that plaster flicks, can be under fire 180-1800 weight portion Plumbum preparatium, can be red down several times, and ceaselessly stir, following pellet should not be too fast, and is also unsuitable excessive, treats to can be made into when plaster is black emplastrum.
9, a kind of pharmaceutical composition for the treatment of rheumatism atrophic arthritis according to claim 8, the preparation method that it is characterized in that said composition is: the medicinal 1000 parts by volume Oleum Sesami of above-mentioned raw materials were soaked 3 days, boil with high heat, become withered and yellow black and be advisable by sallow, changing slow fire then into endures slowly, endure to dripping into pearl and filter medicinal residues, taking liquid still boils with slow fire in pot, generally endure to the time about 1-2 hour, the cold water of promptly not stopping using drips medicine inspection to be tested, it is broken being as the criterion that plaster flicks, can be under fire 180 weight portion Plumbum preparatium, can be red down several times, and ceaselessly stir, following pellet should not be too fast, and is also unsuitable excessive, treats to can be made into when plaster is black emplastrum.
10, the application in the medicine of preparation treatment rheumatic arthritis, rheumatoid arthritis, scapulohumeral periarthritis, cervical spondylosis, lumbar spondylosis, sciatica according to claim 1 or 2 or 3 described pharmaceutical compositions.
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| CN 200510055266 CN1833700A (en) | 2005-03-17 | 2005-03-17 | Medicinal compsns. for treating rheumatism and rheumatoid arthritis and its prepn. method |
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| CN 200510055266 CN1833700A (en) | 2005-03-17 | 2005-03-17 | Medicinal compsns. for treating rheumatism and rheumatoid arthritis and its prepn. method |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102430018A (en) * | 2011-11-28 | 2012-05-02 | 朱金光 | Medicinal composition for treating rheumatic and rheumatoid arthritis |
| CN103705658A (en) * | 2013-12-29 | 2014-04-09 | 纪忠义 | Traditional Chinese medicine agent for external application for treatment of rheumatoid arthritis |
| CN103816267A (en) * | 2014-03-10 | 2014-05-28 | 苏幸全 | Chinese herbal medicine agentia and preparation method thereof |
| CN104922443A (en) * | 2015-07-08 | 2015-09-23 | 安徽老同桌生物科技有限公司 | External-use patch for treating rheumatic arthritis |
| CN104971223A (en) * | 2015-06-15 | 2015-10-14 | 李蒋萍 | External traditional Chinese medicine for treating rheumatoid arthritis |
| CN105687611A (en) * | 2014-11-27 | 2016-06-22 | 马广明 | Ointment and preparation method thereof |
| CN109395034A (en) * | 2017-08-18 | 2019-03-01 | 刘永妍 | A kind of plaster that treating osteopathy and preparation method |
| CN109432269A (en) * | 2018-12-24 | 2019-03-08 | 云南秘元堂生物科技有限公司 | A kind of Chinese medicine composition and preparation method, purposes |
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2005
- 2005-03-17 CN CN 200510055266 patent/CN1833700A/en active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102430018A (en) * | 2011-11-28 | 2012-05-02 | 朱金光 | Medicinal composition for treating rheumatic and rheumatoid arthritis |
| CN102430018B (en) * | 2011-11-28 | 2013-06-05 | 朱金光 | Medicinal composition for treating rheumatic and rheumatoid arthritis |
| CN103705658A (en) * | 2013-12-29 | 2014-04-09 | 纪忠义 | Traditional Chinese medicine agent for external application for treatment of rheumatoid arthritis |
| CN103705658B (en) * | 2013-12-29 | 2016-03-30 | 纪忠义 | A kind of external traditional Chinese medicinal application for the treatment of rheumatoid arthritis |
| CN103816267A (en) * | 2014-03-10 | 2014-05-28 | 苏幸全 | Chinese herbal medicine agentia and preparation method thereof |
| CN103816267B (en) * | 2014-03-10 | 2016-05-11 | 苏幸全 | A kind of Chinese medicinal herb medicament and preparation method thereof |
| CN105687611A (en) * | 2014-11-27 | 2016-06-22 | 马广明 | Ointment and preparation method thereof |
| CN104971223A (en) * | 2015-06-15 | 2015-10-14 | 李蒋萍 | External traditional Chinese medicine for treating rheumatoid arthritis |
| CN104922443A (en) * | 2015-07-08 | 2015-09-23 | 安徽老同桌生物科技有限公司 | External-use patch for treating rheumatic arthritis |
| CN109395034A (en) * | 2017-08-18 | 2019-03-01 | 刘永妍 | A kind of plaster that treating osteopathy and preparation method |
| CN109432269A (en) * | 2018-12-24 | 2019-03-08 | 云南秘元堂生物科技有限公司 | A kind of Chinese medicine composition and preparation method, purposes |
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