CN1628735A - Chinese medicine for treating bone disease and its preparation - Google Patents
Chinese medicine for treating bone disease and its preparation Download PDFInfo
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- CN1628735A CN1628735A CN 200310118426 CN200310118426A CN1628735A CN 1628735 A CN1628735 A CN 1628735A CN 200310118426 CN200310118426 CN 200310118426 CN 200310118426 A CN200310118426 A CN 200310118426A CN 1628735 A CN1628735 A CN 1628735A
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Abstract
Disclosed is a Chinese medicine for treating bone disease and its preparation, wherein the medicine comprises pill and soup, the pill is prepared from Chinese medicinal herbs including ephedra sinica, seed of nuxvomica, frankincense, rhizoma corydalis, notopterygium root, cassia twig, homalomena rhizoma, prepared Sichuan aconite root, prepared wild aconite root, achyranthes root, native copper, Chinese angelica root, licorice root, large-leaf gentian root, dipsacus root, colophony, drynaria, prepared rhizome of rehmannia, buthus martensi kirsch, eucommia bark, epimeddium, broomrape, spatholobus stem.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of bone disease, particularly relate to a kind of Chinese medicine and manufacture method for the treatment of bone disease.
Background technology
In China, also there is not document announcement at present, can thoroughly effect a radical cure rheumatic arthritis, the specific prescription and medication of bone matrix hyperplasia.
Summary of the invention
Purpose one of the present invention provides and a kind ofly can promote cartilage metabolism, improve the chondrocyte function, postponing the cell degeneration takes orally+external, make effective ingredient directly infiltrate the focus part, softening, the vertebral pulp of absorption edema, bulging, the various symptoms that alleviation is oppressed and stimulated the peripheral nerve blood vessel to cause because of adhesion, therapeutic effect is treated the Chinese medicine and the manufacture method of the Chinese medicine pill treatment bone disease of bone disease significantly, and two provide a kind of topical agent that uses simultaneously with pill, and manufacture method.
The purpose technical scheme that realizes foregoing invention is: the Chinese medicine pill of treatment bone disease, make by the medicine of following weight percent content: (life) Herba Ephedrae 3-10, (moxibustion) Semen Strychni 3-10, Olibanum 2-5, rhizoma corydalis 2-5, Rhizoma Et Radix Notopterygii 2-5, Ramulus Cinnamomi 2-4, Rhizoma Homalomenae 3-8, (system) Radix Aconiti 3-8, (system) Radix Aconiti Kusnezoffii 3-8, (bosom) Radix Achyranthis Bidentatae 2-5, Pyritum 1-4, Radix Angelicae Sinensis 1-3, (life) Radix Glycyrrhizae 1-3, Radix Gentianae Marcrophyllae 2-8, Radix Dipsaci 2-8, Lignum Pini Nodi 2-10, Radix Stephaniae Tetrandrae 4-8, (scalding) Rhizoma Drynariae 3-10, Radix Rehmanniae Preparata 3-10, Herba Pyrolae 3-10, Scorpio 2-4, (salt) Cortex Eucommiae 4-8, Herba Epimedii 4-8, Herba Cistanches 4-8, Caulis Spatholobi 4-8.Its manufacture method, with 25 kinds of Chinese medicines in proportion pulverize separately become smalls, cross 120 mesh sieves, practicing honey is ball, every ball weighs 6 and restrains.
Traditional Chinese medicine liquid with the matching used treatment bone disease of pill, by making of the medicine of following weight percent content, Folium Hibisci Mutabilis 4-6, Xu normal minister in ancient times 4-6, Radix Zanthoxyli 13-15, Cinnabaris 2-6, Herba Menthae 2-6, Camphora 2-6, Pterospermi Heterophylli 2-6, Radix stephaniae tetrandrae 4-9, rhizoma corydalis 4-9, Herba Asari 2-6, Semen Strychni (smashing) 4-9, Cortex Cinnamomi 4-6, Rhizoma Drynariae 13-15, Pheretima 4-9, Herba sambuci chinensis 13-15.Its manufacture method proposes Herba Menthae, Camphora, Cortex Cinnamomi separately, and remaining all medicines are put in 1000 milliliters of 50 ° of Chinese liquor, put into container then, fire was closed in 15 minutes at a simmer in the boiled back of elder generation's intense fire, put into Herba Menthae, Camphora and Cortex Cinnamomi then and sealed 3 days, extracting juice bottling after three days.
Pharmacological property analysis of the present invention:
One, pill
Herba Ephedrae: (1) delivers warming the interior, agitates yang-energy, and in the logical natural fibre line of meat, a surname's blood stasis dispelling.
(2) ephedrine can improve central pain, feels threshold value to produce analgesic activity, joins Ramulus Cinnamomi, help the power of its relieving the exterior syndrome by diaphoresis, make again pathogen go and seek defend and, join thermally, it is dry to make its suffering, the taste on ground of can reducing phlegm and internal heat again is greasy, and the effect of playing kidney tonifying tonify deficiency, warm promoting blood circulation altogether is used for the disease of stagnation of cold-damp venation.
Semen Strychni: (1) activating collaterals and eliminating stagnation, a surname's blood stasis dispelling subduing swelling and relieving pain.
(2) open meridians, reach the power in joint thoroughly, far win its medicine." Records of Tradition Chinese and Western Medicine in Combination "
(3) mice acetic acid twisting experiment: have remarkable analgesic activity, be only second to dolantin, the persistent period but is 4 times of dolantin.(the precious Lignum Rhamnellae of grandson: clinical conventional Chinese medicine laboratory manual, 338 pages)
Olibanum: (1) promoting blood circulation and stopping pain Shujin act as easing pain and diminishing inflammation.
(2) fragrance is walked to scurry, and interior a surname is led to internal organs, and external enwergy reaches meridians thoroughly.
(3) " pearl sac " .... fixed all warps are pain.
Rhizoma corydalis: (1) analgesia, the second element is roughly suitable with dolantin to slight spasmic pain effective percentage.
(2) calmness.
(3) pain that a variety of causes is caused is all effective.
Rhizoma Et Radix Notopterygii: (1) expelling wind and dampness pain relieving, especially with the upper part of the body, back positive middle part muscle creeping chill and contracture good effect.
(2) to the sufficient swollen inhibitory action that has of rat formaldehyde.
(3) have significantly analgesic, antalgic and inflammation relieving antiallergic and antibacterial action.Ramulus Cinnamomi: (1) dispelling cold by warming the meridian.
(2) experimental animal models formaldehyde inflammation (especially with omarthritis) there is strong inhibitory action.
Radix Aconiti: (1) dispelling cold by warming the meridian twelve regular channels that passes through, and stopping numbness pain.
(2) experimental (formaldehyde and Ovum Gallus domesticus album) arthritis there is obvious antiinflammation.
(bosom) Radix Achyranthis Bidentatae: (1) invigorating the liver and kidney, Shujin bone strengthening.
(2) enhancing human body immunity.
(3) swelling has obvious antiinflammation to the Radix Achyranthis Bidentatae medicated wine to rat formaldehyde toe.Join the Cortex Eucommiae, Herba Cistanches, the liver and the kidney tonifying, marrow is filled in replenishing essence.Three medicines mutually 5, liver fill muscle and get flourishly, and kidney fills bone and improves oneself.
Pyritum: (1) is treated folding and is hindered the dissipating blood stasis blood and relieving pain.
(2) vital energy regualting and blood circulation-promoting.
Radix Angelicae Sinensis: nourish blood (1), promoting the circulation of blood, and experimentation confirms to have many-sided pain relieving usefulness.
(2) central analgesia, calmness.
(3) strengthen the macrophage phagocytic ability, the human body immunity improving function impels inflammation to disappear, and local edema absorbs, and reaches analgesic effect.
(life) Radix Glycyrrhizae: (1) separates hundred poison of drug, concocts all medicines, detoxifies by adsorption and the effect of class adrenocortical hormone.
(2) antiinflammatory, the resistance attitude has obvious inhibitory action to the inflammation of chronic granulation tissue hyperplasia.
(3) hepatoprotective effect.
Radix Gentianae Macrophyllae: (1) wind-damp dispelling, Shujin network, stopping numbness pain.
(2) can suppress experimental arthritis, the antiinflammatory principle is by nervous system indirect stimulation hypophysis, and the corticotropin secretion is increased, and adrenal cortex function is hyperfunction, thereby helps the antiinflammatory detumescent.
Radix Dipsaci: (1) invigorating the liver and kidney, bone and muscle strengthening, treatment lumbago and skelalgia.
Lignum Pini Nodi: (1) dispeiling pathogenic wind and removing dampness, its effect may be analgesia.
(2) the kind wind and cold of controlling between muscles and bones is wet.
Radix Stephaniae Tetrandrae: (1) expelling wind and removing dampness heat clearing away, it act as analgesia and diuresis.
(2) antiinflammatory, antiallergic has one antiinflammation to rat experiment arthritis.
(3) liver protection effect.
(4) treatment neuropathic pain, lumbosacral radiculitis especially, lumbar vertebra hyperosteogeny merges the pain that radiculitis causes.
Rhizoma Drynariae: (1) the kidney invigorating bone strengthening, pain relieving reuniting the fractured tendons and bones.
(2) antiinflammatory action: to the experiment of rat bone arthritis model, have the chondrocyte of improvement function, improve osteoarticular metabolism, postpone the cell degeneration, join Radix Rehmanniae Preparata, blood enriching and generation of vital essence promoting is filled out marrow.
Radix Rehmanniae Preparata: (1) nourishing the blood and yin, vital essence replenishing and marrow benifiting.
(2) immunosuppressive action, in the experiment in vitro, Radix Rehmanniae Preparata extract F108 shows as the conversion that suppresses the synthetic and T of lymphocytic DNA, bone-marrow-derived lymphocyte, joins Herba Ephedrae, and one mends one looses, and it is unimpeded that meridian qi and blood is able to.
Herba Pyrolae: (1) wind-damp dispelling, bone and muscle strengthening, treatment rheumatism osteoarthritis.
Scorpio: (1) endogenous wind stopping relieving convulsion, detoxicating and resolving stagnation of pathogens, removing obstruction in the collateral to relieve pain.
(2) treatment rheumatism paralysis, joint deformity, the contracture of muscle arteries and veins, it is deep by the wet wind that removes to wear muscle.
(3) analgesia mice torsional technique, the radiation tail-flick method, experiment confirms such as rat trigeminal cortical evoked potential method, scorpion venom has stronger analgesic activity.
(4) the convulsions effect that strychnine alkali causes in the antagonism Semen Strychni is remarkable, and has the effect of lasting blood pressure lowering.
The Cortex Eucommiae: (1) tonifying liver and kidney and strengthening bones and muscles, antiinflammatory, analgesia.
(2) have anti-sclerotin decalcification, be used for osteoporosis.
(3) enhancing human body immunity.
Herba Epimedii: (1) kidney invigorating and YANG supporting, expelling wind and removing dampness.
(2) antiinflammatory action, subcutaneous injection Herba Epimedii methanolic extract can alleviate rat Ovum Gallus domesticus album swollen feet degree.
Herba Cistanches: (1) kidney nourishing and replenishing vital essence, support the gate of vitality, mend five kinds of strain and seven kinds of impairment.
(2) raise immunity improves level of adrenocortical hormone.
Caulis Spatholobi: (1) promoting the circulation of blood is promoted blood circulation, warm waist knee joint, and promoting the circulation of blood is enriched blood, the relaxing muscles and tendons and activating QI and blood in the collateral pain relieving.
(2) animal formaldehyde arthritis there is significant curative effect.
(3) treatment rheumatoid bone bi-syndrome disease and the asthenia of qi and blood weak person that holds concurrently is good.
Rhizoma Homalomenae: (1) when dispeling the wind, the meridian dredging.
(2) antiinflammatory has obvious inhibitory action to carrageenin foot edema.Pharmacological property behind full side's compatibility:
1, powerful wind dispelling cold expelling, blood circulation promoting and blood stasis dispelling, eliminating dampness and dredging channels, the effect of reducing swelling and alleviating pain are arranged.
2, liver and kidney tonifying, bone and muscle strengthening, softening hypertrophy is improved the chondrocyte function, postpones the change of the cell property carried out, and delays articular degeneration, aging.
3, no any toxicity and incompatibility (Semen Strychni after concocting, compatibility Scorpio strychnine alkali perform toxic attenuation).Clinical verification is safe and reliable, effective percentage 98%-100% (waiting experimentation).
Two, medicinal liquid
Pharmacological property is analyzed:
Folium Hibisci Mutabilis: removing pathogenic heat from blood and toxic substance from the body, reducing swelling and alleviating pain is used for traumatic injury, and congestion swells and ache, external application.
Radix Cynanchi Paniculati: wind-damp dispelling, it is antibiotic to detoxify, and is used for rheumatism, rheumatoid arthritis, traumatic injury, external application.
Pterospermi Heterophylli: expelling wind and removing dampness, promoting blood circulation and detumescence is used for the treatment of rheumatic arthralgia, chronic arthritis, sciatica, lumbar muscle strain, osteopatia sprain, congestion swells and ache, external application.
Herba Asari: jiao dispelling cold and analgesia eliminates the phlegm.Zoopery shows that the periglottis to animal nerve tip and people has local anesthetic action.External application.
Herba Menthae: antiinflammatory, antipruritic (containing volatile oil) dispeled the wind in analgesia.
Cortex Cinnamomi: warming spleen and stomach for dispelling cold, the mediation blood vessels, a surname leads hundred medicines, blood vessel dilating, blood circulation promoting.
Radix Zanthoxyli: ease pain (1), and the harmonization of the stomach articular muscle is felt sorry all mitigation, and topical application has certain anesthetic action to teleneuron.
(2) removing blood stasis to reduce swelling, treatment treating swelling and pain by traumatic injury, muscle ligament sprain, contusion, local external application.
Rhizoma corydalis: (1) analgesia, second Lee's effective percentage that eases pain is suitable with dolantin.
(2) spasmolytic makes of flaccid muscles.
(3) invigorate blood circulation, regulate the flow of vital energy.
Herba sambuci chinensis: (1) promoting the circulation of blood hemostasis: promoting blood circulation to remove blood stasis, make regional flow vigorous, quicken hematoma, inflammatory resolution.
(2) accelerating union of bone fracture can promote callus formation and calcinosis.
Rhizoma Drynariae: the kidney invigorating analgesia, blood-activating bone-strengthening, anti-osteoarthritis, treatment hyperosteogeny.
Semen Strychni: pain relieving, brucine has the paralysis effect to sensory nerve ending, treatment traumatic injury, bruise, arthralgia is got its strong pain-relieving effect.
Camphora: local irritant effect, can cause slight consciousness paralysis, external application for curing partial gall and traumatic injury, the stasis of blood stagnates and swells and ache.
Cinnabaris: anticorrosion, detoxifcation.
Pheretima: (1) channels sootheing and network vessel quickening.
(2) anticoagulant, anti thrombotic action, experiment in vitro prove that its extracting solution has good anticoagulation, and also have fibrinolysis activity, and the lyase effect can make the fine swollen dissolving of established thrombosis.
Radix stephaniae tetrandrae: (1) promoting diuresis to eliminate damp pathogen pain relieving, antiinflammatory antiallergic (arthritis).
(2) skeletal muscle there is certain relexation, does the muscle relaxant of auxiliary anesthesia.
(3) treatment neuropathic pain (lumbosacral radiculitis, hyperosteogeny causes neuralgia).
Behind full side's compatibility, have and promote that joint and intervertebral foramina, hypertrophy position peripheral nerve root inflammatory edema disappear, adhesion is removed, improve spinal cord and nerve roots, hypertrophy position and close the circulation of internode peripheral blood, promote bone metabolism, improve the chondrocyte function, thereby alleviate and the dissipation inflammatory edema, remove nerve root tension force, make inflammation eliminate and recover.
Advantage of the present invention is: pill adds medicinal liquid matching used with it, because therapeutic process is the external application that adds for oral administration, can promote cartilage metabolism, improve the chondrocyte function, postpone the cell degeneration and take orally+external, make effective ingredient directly infiltrate the focus part, softening, absorb the vertebral pulp of edema, bulging, alleviate the various symptoms of oppressing and stimulating the peripheral nerve blood vessel to cause because of adhesion.By bone and muscle strengthening, liver and kidney tonifying, make the sclerotin of having degenerated obtain filling and repairing; By expelling wind and cold, blood circulation promoting and blood stasis dispelling makes meridians unimpeded, and treating both the principal and secondary aspects of a disease reaches the purpose of thorough radical cure.Raw material of Chinese medicine of the present invention in addition is easy to get, and is common drug, and the medicine source is abundant, low price, and manufacture method is simple, and therapeutic effect is remarkable.
The specific embodiment
Below in conjunction with embodiment the present invention is done further detailed description.
The present invention is made up of pill (being referred to as the logical ball of rheumatism involving the bone) and medicinal liquid (thorn liquid is referred to as to disappear), and pill and medicinal liquid use simultaneously, and pill is made up of 25 kinds of Chinese medicines, and pill medication component and weight percent content embodiment are as follows:
1, (life) Herba Ephedrae 3, (moxibustion) Semen Strychni 8, Olibanum 2, rhizoma corydalis 3, Rhizoma Et Radix Notopterygii 5, Ramulus Cinnamomi 4, Rhizoma Homalomenae 3, (system) Radix Aconiti 8, (system) Radix Aconiti Kusnezoffii 4, (bosom) Radix Achyranthis Bidentatae 4, Pyritum 1, Radix Angelicae Sinensis 2, (life) Radix Glycyrrhizae 1, Radix Gentianae Marcrophyllae 8, Radix Dipsaci 8, Lignum Pini Nodi 2, Radix Stephaniae Tetrandrae 4, (scalding) Rhizoma Drynariae 3, Radix Rehmanniae Preparata 4, Herba Pyrolae 3, Scorpio 2, (salt) Cortex Eucommiae 4, Herba Epimedii 5, Herba Cistanches 5, Caulis Spatholobi 4.
2, (life) Herba Ephedrae 10, (moxibustion) Semen Strychni 3, Olibanum 5, rhizoma corydalis 2, Rhizoma Et Radix Notopterygii 2, Ramulus Cinnamomi 2, Rhizoma Homalomenae 8, (system) Radix Aconiti 3, (system) Radix Aconiti Kusnezoffii 8, (bosom) Radix Achyranthis Bidentatae 2, Pyritum 4, Radix Angelicae Sinensis 1, (life) Radix Glycyrrhizae 3, Radix Gentianae Marcrophyllae 2, Radix Dipsaci 2, Lignum Pini Nodi 3, Radix Stephaniae Tetrandrae 5, (scalding) Rhizoma Drynariae 5, Radix Rehmanniae Preparata 3, Herba Pyrolae 5, Scorpio 4, (salt) Cortex Eucommiae 5, Herba Epimedii 4, Herba Cistanches 4, Caulis Spatholobi 5.
3, (life) Herba Ephedrae 5, (moxibustion) Semen Strychni 5, Olibanum 3, rhizoma corydalis 4, Rhizoma Et Radix Notopterygii 3, Ramulus Cinnamomi 3, Rhizoma Homalomenae 5, (system) Radix Aconiti 5, (system) Radix Aconiti Kusnezoffii 3, (bosom) Radix Achyranthis Bidentatae 5, Pyritum 2, Radix Angelicae Sinensis 3, (life) Radix Glycyrrhizae 2, Radix Gentianae Marcrophyllae 5, Radix Dipsaci 3, Lignum Pini Nodi 2, Radix Stephaniae Tetrandrae 6, (scalding) Rhizoma Drynariae 3, Radix Rehmanniae Preparata 3, Herba Pyrolae 3, Scorpio 3, (salt) Cortex Eucommiae 6, Herba Epimedii 4, Herba Cistanches 6, Caulis Spatholobi 8.
4, (life) Herba Ephedrae 5, (moxibustion) Semen Strychni 6, Olibanum 4, rhizoma corydalis 2, Rhizoma Et Radix Notopterygii 2, Ramulus Cinnamomi 2, Rhizoma Homalomenae 3, (system) Radix Aconiti 3, (system) Radix Aconiti Kusnezoffii 3, (bosom) Radix Achyranthis Bidentatae 2, Pyritum 1, Radix Angelicae Sinensis 1, (life) Radix Glycyrrhizae 1, Radix Gentianae Marcrophyllae 2, Radix Dipsaci 2, Lignum Pini Nodi 5, Radix Stephaniae Tetrandrae 4, (scalding) Rhizoma Drynariae 10, Radix Rehmanniae Preparata 8, Herba Pyrolae 4, Scorpio 2, (salt) Cortex Eucommiae 8, Herba Epimedii 8, Herba Cistanches 8, Caulis Spatholobi 4.
5, (life) Herba Ephedrae 6, (moxibustion) Semen Strychni 5, Olibanum 2, rhizoma corydalis 5, Rhizoma Et Radix Notopterygii 4, Ramulus Cinnamomi 2, Rhizoma Homalomenae 4, (system) Radix Aconiti 4, (system) Radix Aconiti Kusnezoffii 5, (bosom) Radix Achyranthis Bidentatae 3, Pyritum 3, Radix Angelicae Sinensis 2, (life) Radix Glycyrrhizae 1, Radix Gentianae Marcrophyllae 6, Radix Dipsaci 5, Lignum Pini Nodi 10, Radix Stephaniae Tetrandrae 4, (scalding) Rhizoma Drynariae 4, Radix Rehmanniae Preparata 3, Herba Pyrolae 4, Scorpio 2, (salt) Cortex Eucommiae 4, Herba Epimedii 4, Herba Cistanches 4, Caulis Spatholobi 4.
6, (life) Herba Ephedrae 3, (moxibustion) Semen Strychni 10, Olibanum 2, rhizoma corydalis 2, Rhizoma Et Radix Notopterygii 2, Ramulus Cinnamomi 2, Rhizoma Homalomenae 3, (system) Radix Aconiti 3, (system) Radix Aconiti Kusnezoffii 4, (bosom) Radix Achyranthis Bidentatae 2, Pyritum 1, Radix Angelicae Sinensis 2, (life) Radix Glycyrrhizae 3, Radix Gentianae Marcrophyllae 4, Radix Dipsaci 4, Lignum Pini Nodi 2, Radix Stephaniae Tetrandrae 8, (scalding) Rhizoma Drynariae 3, Radix Rehmanniae Preparata 10, Herba Pyrolae 10, Scorpio 2, (salt) Cortex Eucommiae 5, Herba Epimedii 4, Herba Cistanches 5, Caulis Spatholobi 4.
7, (life) Herba Ephedrae 8.9, (moxibustion) Semen Strychni 8.9, Olibanum 2.7, rhizoma corydalis 2.6, Rhizoma Et Radix Notopterygii 2.6, Ramulus Cinnamomi 1.1, Rhizoma Homalomenae 2.2, (system) Radix Aconiti 2.2, (system) Radix Aconiti Kusnezoffii 2.2, (bosom) Radix Achyranthis Bidentatae 2.6, Pyritum 2.6, Radix Angelicae Sinensis 1.1, (life) Radix Glycyrrhizae 1.1, Radix Gentianae Marcrophyllae 2.2, Radix Dipsaci 2.2, Lignum Pini Nodi 2.7, Radix Stephaniae Tetrandrae 4.4, (scalding) Rhizoma Drynariae 8.9, Radix Rehmanniae Preparata 8.9, Herba Pyrolae 8.9, Scorpio 3.4, (salt) Cortex Eucommiae 4.4, Herba Epimedii 4.4, Herba Cistanches 4.4, Caulis Spatholobi 4.4.
8, (life) Herba Ephedrae 3.9, (moxibustion) Semen Strychni 3.9, Olibanum 2.7, rhizoma corydalis 2.6, Rhizoma Et Radix Notopterygii 2.7, Ramulus Cinnamomi 2.6, Rhizoma Homalomenae 3.9, (system) Radix Aconiti 3.9, (system) Radix Aconiti Kusnezoffii 3.9, (bosom) Radix Achyranthis Bidentatae 2.6, Pyritum 1.5, Radix Angelicae Sinensis 2.6, (life) Radix Glycyrrhizae 2.6, Radix Gentianae Marcrophyllae 2.6, Radix Dipsaci 2.7, Lignum Pini Nodi 1.5, Radix Stephaniae Tetrandrae 7.9, (scalding) Rhizoma Drynariae 3.9, Radix Rehmanniae Preparata 3.9, Herba Pyrolae 2.6, Scorpio 7.9, (salt) Cortex Eucommiae 7.9, Herba Epimedii 7.9, Herba Cistanches 7.9, Caulis Spatholobi 7.9.
The manufacture method embodiment of this pill: with 25 kinds of Chinese medicines according to the above ratio pulverize separately become smalls, cross 120 mesh sieves, then they are mixed, add Mel 250-300 gram and practice honey and be ball, every ball weighs 6 grams, is oral medicine.
Medicinal liquid of the present invention (thorn liquid is referred to as to disappear) is made up of 15 kinds of Chinese medicines, is and the matching used external application medicinal liquid of pill that medicinal liquid component and weight percent content embodiment are as follows:
1, Folium Hibisci Mutabilis 4, the normal minister in ancient times 5 of Xu, Radix Zanthoxyli 13, Cinnabaris 2, Herba Menthae 5, Camphora 5, Pterospermi Heterophylli 6, Radix stephaniae tetrandrae 4, rhizoma corydalis 5, Herba Asari 2, Semen Strychni (smashing) 4, Cortex Cinnamomi 6, Rhizoma Drynariae 15, Pheretima 9, Herba sambuci chinensis 15.
2, Folium Hibisci Mutabilis 5, the normal minister in ancient times 6 of Xu, Radix Zanthoxyli 14, Cinnabaris 6, Herba Menthae 2, Camphora 6, Pterospermi Heterophylli 2, Radix stephaniae tetrandrae 6, rhizoma corydalis 4, Herba Asari 6, Semen Strychni (smashing) 9, Cortex Cinnamomi 4, Rhizoma Drynariae 13, Pheretima 4, Herba sambuci chinensis 13.
3, Folium Hibisci Mutabilis 6, the normal minister in ancient times 4 of Xu, Radix Zanthoxyli 15, Cinnabaris 3, Herba Menthae 6, Camphora 2, Pterospermi Heterophylli 3, Radix stephaniae tetrandrae 9, rhizoma corydalis 5, Herba Asari 4, Semen Strychni (smashing) 5, Cortex Cinnamomi 5, Rhizoma Drynariae 14, Pheretima 5, Herba sambuci chinensis 14.
4, Folium Hibisci Mutabilis 5, the normal minister in ancient times 6 of Xu, Radix Zanthoxyli 13, Cinnabaris 2, Herba Menthae 4, Camphora 3, Pterospermi Heterophylli 4, Radix stephaniae tetrandrae 5, rhizoma corydalis 9, Herba Asari 3, Semen Strychni (smashing) 6, Cortex Cinnamomi 6, Rhizoma Drynariae 15, Pheretima 4, Herba sambuci chinensis 15.
5, Folium Hibisci Mutabilis 4.8, the normal minister in ancient times 4.8 of Xu, Radix Zanthoxyli 14.2, Cinnabaris 4.8, Herba Menthae 4.8, Camphora 4.8, Pterospermi Heterophylli 4.8, Radix stephaniae tetrandrae 4.8, rhizoma corydalis 4.8, Herba Asari 4.6, Semen Strychni (smashing) 4.8, Cortex Cinnamomi 4.8, Rhizoma Drynariae 14.2, Pheretima 4.8, Herba sambuci chinensis 14.2.
6, Folium Hibisci Mutabilis 5.8, the normal minister in ancient times 5.8 of Xu, Radix Zanthoxyli 14.7, Cinnabaris 2.9, Herba Menthae 2.9, Camphora 2.9, Pterospermi Heterophylli 2.9, Radix stephaniae tetrandrae 7.8, rhizoma corydalis 7.8, Herba Asari 2.8, Semen Strychni (smashing) 7.8, Cortex Cinnamomi 5.8, Rhizoma Drynariae 14.7, Pheretima 7.7, Herba sambuci chinensis 7.7.
Manufacture method of liquid embodiment: Herba Menthae, Camphora, Cortex Cinnamomi are proposed separately, and remaining all medicines are put in 1000 milliliters of 50 ° of Chinese liquor.Put into porcelain or aluminum basin then, fire was closed in 15 minutes at a simmer in the boiled back of first intense fire, put into Herba Menthae, Camphora and Cortex Cinnamomi then and sealed 3 days, after three days the extracting juice bottling standby, external application does not enter mouth.
Instructions of taking of the present invention: pill every day early, respectively obey a ball evening, yellow wine takes.Simultaneously smear medicinal liquid in the affected part.
Typical case's case history:
(1) Gu Shifan, man, 40 years old, Hancheng, Tangshan people from town, the prescription on individual diagnosis in 26, of one 999 on December, X-ray examination, hyperosteogeny, bed reaches 1 year, the logical ball of clothes rheumatism involving the bone got final product out-of-bed activity in 15 days, obeyed to get final product outdoor walking in 30 days, and transference cure after 60 days is followed up a case by regular visits to so far recurrence.
(2) Gu Shaojing, the man, 52 years old, Hancheng, Tangshan City people from town, on January 16th, 2000 went to a doctor, X-ray examination, hyperosteogeny was liied in bed 3 months.But the logical 15 days out-of-bed activities of ball of clothes rheumatism involving the bone, 1 li of can walking after 20 days, transference cure after 60 days, recovery from illness.
(3) Li Huizhen, the woman, 51 years old, the west of a river, town, Hancheng, Tangshan City people from village, coal is cured attached CT examination, prolapse of lumbar intervertebral disc, the logical ball of clothes rheumatism involving the bone 15 days, pain subtracts (standing up difficulty before the prescription on individual diagnosis) greatly, and the thorn liquid that disappears of external application simultaneously is after 30 days, the waist activity has had a pain in the leg regularly freely, after 45 days, and can be by bike.Clinical symptom disappearance so far.
The clinical statistics data:
20 of patient medical histories, age 32-67 year, male 12 people, women 8 people all have clinical symptoms and X-ray sheet, the inspection of CT sheet, ill 2 months-8 years.Stop all treatments during advising its treatment, oral rheumatism involving the bone lead to ball, and (every ball 6 grammes per square metres) every day morning, respectively obey a ball evening, and yellow wine takes.The thorn liquid that disappears of external application simultaneously, every day 2 times, each 60 minutes, average medication 45 days.Follow-up study, the result shows, Most patients was taken medicine 5-15 days, symptom is obviously improved, and after 30 days, arthralgia and mobility are significantly improved, statistical result shows, the obvious improver of symptom accounts for 98%, and moderate improver accounts for 100%, and no improver accounts for 0%. and do not find toxic side effects and serious adverse reaction.
The present invention is for oral administration to add the external application prescription, has the anti-bone regeneration preparation of other classes (watered pill, tablet), the not available remarkable advantage of rheumatism class preparation.For example:, liver is had obvious damage, and the curative effect performance is also not obvious by " ZHUANGGU GUANJIE WAN " (accurate word of traditional Chinese medicines) of Radix Angelicae Pubescentis, Herba Epimedii participation prescription.Part Chinese herbal medicine among the present invention has hepatoprotective and antiallergic and hypotensive effect, and the curative effect performance obviously, and the pain stop and anti-inflammation effect is remarkable.
Claims (2)
1, a kind of Chinese medicine for the treatment of bone disease is made up of pill and medicinal liquid, it is characterized in that,
A, pill is made by the medicine of following weight percent content: (life) Herba Ephedrae 3-10, (moxibustion) Semen Strychni 3-10, Olibanum 2-5, rhizoma corydalis 2-5, Rhizoma Et Radix Notopterygii 2-5, Ramulus Cinnamomi 2-4, Rhizoma Homalomenae 3-8, (system) Radix Aconiti 3-8, (system) Radix Aconiti Kusnezoffii 3-8, (bosom) Radix Achyranthis Bidentatae 2-5, Pyritum 1-4, Radix Angelicae Sinensis 1-3, (life) Radix Glycyrrhizae 1-3, Radix Gentianae Marcrophyllae 2-8, Radix Dipsaci 2-8, Lignum Pini Nodi 2-10,4-8 prevented in the Chinese, (scalding) Rhizoma Drynariae 3-10, Radix Rehmanniae Preparata 3-10, Herba Pyrolae 3-10, Scorpio 2-4, (salt) Cortex Eucommiae 4-8, Herba Epimedii 4-8, Herba Cistanches 4-8, Caulis Spatholobi 4-8;
B, medicinal liquid make Folium Hibisci Mutabilis 4-6, Xu normal minister in ancient times 4-6, Radix Zanthoxyli 13-15, Cinnabaris 2-6, Herba Menthae 2-6, Camphora 2-6, Pterospermi Heterophylli 2-6, powder anti-4-9, rhizoma corydalis 4-9, Herba Asari 2-6, Semen Strychni (smashing) 4-9, Cortex Cinnamomi 4-6, Rhizoma Drynariae 13-15, Pheretima 4-9, Herba sambuci chinensis 13-15 by the medicine of following weight percent content.
2, a kind of manufacture method of Chinese medicine of treatment bone disease as claimed in claim 1 is characterized in that,
A, pill: with 25 kinds of Chinese medicines in proportion pulverize separately become smalls, cross 120 mesh sieves, practicing honey is ball, every ball weighs 6 and restrains;
B, medicinal liquid: Herba Menthae, Camphora, Cortex Cinnamomi are proposed separately, remaining all medicines are put in 1000 milliliters of 50 ° of Chinese liquor, put into container then, and the boiled back of first intense fire was closed fire in 15 minutes at a simmer, put into Herba Menthae, Camphora and Cortex Cinnamomi then and sealed 3 days, extracting juice bottling after three days.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2007043810A1 (en) * | 2005-10-14 | 2007-04-19 | Industry-Academic Cooperation Foundation, Yonsei University | Compositions comprising the extract of roasted licorice for preventing and treating bone diseases |
| CN1316987C (en) * | 2005-11-04 | 2007-05-23 | 徐英洲 | Recipe of plaster for treating cervical vertebra and lumber vertebra arthritis |
| CN101732450B (en) * | 2008-11-13 | 2011-06-08 | 李桂英 | Medicinal liquor for treating rheumatic arthritis |
| CN102697883A (en) * | 2012-06-04 | 2012-10-03 | 蒋月芳 | Plaster for treating osteoarthritis |
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| CN103386108A (en) * | 2013-07-19 | 2013-11-13 | 苏州市天灵中药饮片有限公司 | Decoction for treating rheumatism arthralgia |
| CN105168561A (en) * | 2015-09-07 | 2015-12-23 | 孙太辉 | Medicine for treating painful heel and preparation method of medicine |
| CN107412485A (en) * | 2017-04-28 | 2017-12-01 | 肖连宇 | A kind of traditional Chinese medicinal lotion for treating arteriosclerosis and obstruction of lower limbs |
| CN111329921A (en) * | 2020-04-26 | 2020-06-26 | 罗宗坤 | Traditional Chinese medicine composition for treating arthralgia and myalgia as well as medicine, preparation method and application thereof |
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2003
- 2003-12-16 CN CN 200310118426 patent/CN1256969C/en not_active Expired - Fee Related
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007043810A1 (en) * | 2005-10-14 | 2007-04-19 | Industry-Academic Cooperation Foundation, Yonsei University | Compositions comprising the extract of roasted licorice for preventing and treating bone diseases |
| CN1316987C (en) * | 2005-11-04 | 2007-05-23 | 徐英洲 | Recipe of plaster for treating cervical vertebra and lumber vertebra arthritis |
| CN101732450B (en) * | 2008-11-13 | 2011-06-08 | 李桂英 | Medicinal liquor for treating rheumatic arthritis |
| CN102697883A (en) * | 2012-06-04 | 2012-10-03 | 蒋月芳 | Plaster for treating osteoarthritis |
| CN103055216A (en) * | 2013-02-01 | 2013-04-24 | 刘加才 | Three-original ecology tracing conjugate bonesetting reduction health traditional Chinese medicine preparation and preparation method thereof |
| CN103055216B (en) * | 2013-02-01 | 2013-12-25 | 刘加才 | Three-original ecology tracing conjugate bonesetting reduction health traditional Chinese medicine preparation and preparation method thereof |
| CN103386108A (en) * | 2013-07-19 | 2013-11-13 | 苏州市天灵中药饮片有限公司 | Decoction for treating rheumatism arthralgia |
| CN105168561A (en) * | 2015-09-07 | 2015-12-23 | 孙太辉 | Medicine for treating painful heel and preparation method of medicine |
| CN107412485A (en) * | 2017-04-28 | 2017-12-01 | 肖连宇 | A kind of traditional Chinese medicinal lotion for treating arteriosclerosis and obstruction of lower limbs |
| CN111329921A (en) * | 2020-04-26 | 2020-06-26 | 罗宗坤 | Traditional Chinese medicine composition for treating arthralgia and myalgia as well as medicine, preparation method and application thereof |
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| Publication number | Publication date |
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| CN1256969C (en) | 2006-05-24 |
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