CN1809638B - 检测β3肾上腺素受体突变基因的方法及用于该方法的核酸探针和试剂盒 - Google Patents

检测β3肾上腺素受体突变基因的方法及用于该方法的核酸探针和试剂盒 Download PDF

Info

Publication number
CN1809638B
CN1809638B CN2004800170191A CN200480017019A CN1809638B CN 1809638 B CN1809638 B CN 1809638B CN 2004800170191 A CN2004800170191 A CN 2004800170191A CN 200480017019 A CN200480017019 A CN 200480017019A CN 1809638 B CN1809638 B CN 1809638B
Authority
CN
China
Prior art keywords
nucleic acid
probe
fluorescent dye
nucleotide sequence
mutation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN2004800170191A
Other languages
English (en)
Chinese (zh)
Other versions
CN1809638A (zh
Inventor
平井光春
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arkray Inc
Original Assignee
Arkray Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arkray Inc filed Critical Arkray Inc
Publication of CN1809638A publication Critical patent/CN1809638A/zh
Application granted granted Critical
Publication of CN1809638B publication Critical patent/CN1809638B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
CN2004800170191A 2003-04-18 2004-04-16 检测β3肾上腺素受体突变基因的方法及用于该方法的核酸探针和试剂盒 Expired - Fee Related CN1809638B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2003114381A JP4336877B2 (ja) 2003-04-18 2003-04-18 β3アドレナリン受容体変異遺伝子の検出法ならびにそのための核酸プローブおよびキット
JP114381/2003 2003-04-18
PCT/JP2004/005525 WO2004092385A1 (ja) 2003-04-18 2004-04-16 β3アドレナリン受容体変異遺伝子の検出法ならびにそのための核酸プローブおよびキット

Publications (2)

Publication Number Publication Date
CN1809638A CN1809638A (zh) 2006-07-26
CN1809638B true CN1809638B (zh) 2010-12-22

Family

ID=33296148

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2004800170191A Expired - Fee Related CN1809638B (zh) 2003-04-18 2004-04-16 检测β3肾上腺素受体突变基因的方法及用于该方法的核酸探针和试剂盒

Country Status (7)

Country Link
US (1) US7501239B2 (https=)
EP (1) EP1616953B1 (https=)
JP (1) JP4336877B2 (https=)
CN (1) CN1809638B (https=)
AT (1) ATE420957T1 (https=)
DE (1) DE602004019067D1 (https=)
WO (1) WO2004092385A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070176822A1 (en) * 2006-01-30 2007-08-02 Fujitsu Limited Target detection apparatus and system
JPWO2008066162A1 (ja) * 2006-11-30 2010-03-11 アークレイ株式会社 Cyp2c19遺伝子増幅用プライマーセット、それを含むcyp2c19遺伝子増幅用試薬およびその用途
JP5279492B2 (ja) * 2006-11-30 2013-09-04 アークレイ株式会社 肥満遺伝子増幅用プライマーセット、それを含む肥満遺伝子増幅用試薬およびその用途
KR101068605B1 (ko) * 2006-11-30 2011-09-30 아크레이 가부시키가이샤 Nat2 유전자 증폭용 프라이머 셋트, 그것을 포함하는 nat2 유전자 증폭용 시약 및 그 용도
JP6059453B2 (ja) * 2011-05-31 2017-01-11 アークレイ株式会社 同一又は近傍の検出波長を有する蛍光色素で修飾された複数のオリゴヌクレオチドを用いて、1種類の波長で複数の遺伝子多型を検出する方法
JP6145974B2 (ja) * 2012-08-24 2017-06-14 東洋紡株式会社 肺炎マイコプラズマの検出方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
JP2001037489A (ja) * 1999-05-25 2001-02-13 Mitsubishi Chemicals Corp 遺伝子解析法
JP2002034598A (ja) * 2000-07-27 2002-02-05 Toyobo Co Ltd 塩基多型を検出する方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364772A (en) 1992-07-20 1994-11-15 Wayne State University DNA molecule encoding the β3 -adrenergic receptor
US5766851A (en) * 1995-05-19 1998-06-16 The Johns Hopkins University School Of Medicine Susceptibility gene for obesity and type II diabetes mellitus
WO1998020165A2 (en) * 1996-11-06 1998-05-14 Whitehead Institute For Biomedical Research Biallelic markers
US6140054A (en) * 1998-09-30 2000-10-31 University Of Utah Research Foundation Multiplex genotyping using fluorescent hybridization probes
JP3437816B2 (ja) 1999-04-20 2003-08-18 環境エンジニアリング株式会社 核酸の測定方法
JP3963422B2 (ja) * 2000-08-03 2007-08-22 日鉄環境エンジニアリング株式会社 核酸の測定方法
AU1141602A (en) * 2000-10-04 2002-04-15 Celadon Lab Inc Computer system for designing oligonucleotides used in biochemical methods

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
JP2001037489A (ja) * 1999-05-25 2001-02-13 Mitsubishi Chemicals Corp 遺伝子解析法
JP2002034598A (ja) * 2000-07-27 2002-02-05 Toyobo Co Ltd 塩基多型を検出する方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HIRATSUKA MASAHIRO等.A simultaneous LightCycler detection assay for five genetic polymorphisms influencing drug sensitivity.CLINICAL BIOCHEMISTRY.2002,35(1),35-40. *

Also Published As

Publication number Publication date
EP1616953A1 (en) 2006-01-18
EP1616953A4 (en) 2006-06-14
EP1616953B1 (en) 2009-01-14
US20070003932A1 (en) 2007-01-04
DE602004019067D1 (de) 2009-03-05
JP4336877B2 (ja) 2009-09-30
US7501239B2 (en) 2009-03-10
WO2004092385A1 (ja) 2004-10-28
ATE420957T1 (de) 2009-01-15
JP2004313120A (ja) 2004-11-11
CN1809638A (zh) 2006-07-26

Similar Documents

Publication Publication Date Title
US20130084568A1 (en) Probe, and polymorphism detection method using the same
JP6490990B2 (ja) Cyp2c19遺伝子増幅用プライマーセット、cyp2c19遺伝子増幅用キット、遺伝子増幅方法、多型解析方法、及び薬効判定方法
CN102317454A (zh) 疾病相关基因的多态性检测用探针及其用途
CN1809638B (zh) 检测β3肾上腺素受体突变基因的方法及用于该方法的核酸探针和试剂盒
JP5757908B2 (ja) 多型検出用プローブ、多型検出方法、薬効評価方法、疾患予測方法及び多型検出用試薬キット
JP2012105644A (ja) 多型検出用プローブ、多型検出方法、薬効評価方法、および多型検出用キット
CN103352070B (zh) 一种ros1融合基因的筛查方法
JP6153758B2 (ja) 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用キット
JP4505838B2 (ja) Nat2*6の変異の検出法ならびにそのための核酸プローブおよびキット
JP7241634B2 (ja) ヒトbrafのv600変異検出用プローブ及びヒトbrafのv600変異の検出方法
JP6205216B2 (ja) 変異検出用プローブ、変異検出方法、薬効判定方法及び変異検出用キット
JP4454249B2 (ja) 膵ラ氏島アミロイドタンパク質変異遺伝子の検出法ならびにそのための核酸プローブおよびキット
JPWO2011077990A1 (ja) c−kit遺伝子の多型検出用プローブおよびその用途
WO2004092415A1 (ja) ミトコンドリアdna3243変異の検出法および定量法ならびにそのためのキット
JP5860667B2 (ja) Egfrエクソン21l858r遺伝子多型検出用プライマーセット及びその用途
JP4437206B2 (ja) Cyp2c9の変異の検出法ならびにそのための核酸プローブおよびキット
JP6754202B2 (ja) K−ras遺伝子増幅用フォワードプライマーセット、K−ras遺伝子増幅用キット、K−ras遺伝子増幅方法、多型解析方法、及び薬効判定方法
JP4517175B2 (ja) Nat2*7の変異の検出法ならびにそのための核酸プローブおよびキット
JP5047450B2 (ja) Cyp2c19*3アレルの検出法およびそのための核酸プローブ
JP4276874B2 (ja) ミトコンドリアdna3243変異の検出法ならびにそのための核酸プローブおよびキット
JP2005058114A (ja) Cyp2c19の変異の検出法およびそのための核酸プローブ

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20101222

Termination date: 20180416