CN1742890A - Heat-clearing detoxicating diaphoresis wind-expelling medicine for treating wind-heat syndrome such as common cold, and preparation thereof - Google Patents
Heat-clearing detoxicating diaphoresis wind-expelling medicine for treating wind-heat syndrome such as common cold, and preparation thereof Download PDFInfo
- Publication number
- CN1742890A CN1742890A CN 200510112994 CN200510112994A CN1742890A CN 1742890 A CN1742890 A CN 1742890A CN 200510112994 CN200510112994 CN 200510112994 CN 200510112994 A CN200510112994 A CN 200510112994A CN 1742890 A CN1742890 A CN 1742890A
- Authority
- CN
- China
- Prior art keywords
- medicine
- radix
- heat
- isatidiss
- herba houttuyniae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention provides a Chinese medicine with the functions of clearing away heat, removing toxic material, expelling wind and relieving exterior syndrome for effectively curing wind-heat type common cold. It is made up by using 6 Chinese medicinal materials of lonicera flower, isatis leaf, isatis root, gardenia fruit, houttuynia and licorice through a certain preparation process.
Description
Technical field
The present invention relates to the Chinese medicine formulation art, especially relate to a kind of heat-clearing and toxic substances removing, dispelling wind to relieve the exterior syndrome.Be used for medicine of wind-heat cold and preparation method thereof.
Background technology
The traditional Chinese medical science think flu be six climate exopathogens, the time row virus attack human body and causing a disease.Ailment said due to cold or exposure is first of the six climate exopathogens, and the disease of catching a cold is a main cause with the ailment said due to cold or exposure.But in Various Seasonal, often with other in season in gas phase close and hurt sb.'s feelings.Generally both see more with wind and cold, wind heat.If four o'clock six gas are not normal, row virus is hurted sb.'s feelings during gas folder when non-, then easilier causes morbidity, and does not limit season, and the state of an illness is multiple, and heating obviously often infects popular each other.
Have recognized that promptly that as far back as " interior warp " flu mainly is due to the diseases caused by exogenous pathogenic factor ailment said due to cold or exposure." element is asked a bone empty talk piece of writing " said: " wind from outside go into, make us cold with shivering, sweating headache, heavy sensation of the body aversion to cold." two soup cards of " Treatise on Febrile Diseases TAI YANG syndrome " apoplexy of discussing, the Ramulus Cinnamomi of typhoid fever, Herba Ephedrae, essence comprise cold light, weigh two class syndromes.If from having stronger communicable influenza, then again when belonging to " time row disease " and so on.
Due to illness evil from table from top to bottom, in close in lung, so You Yiwei table discord is its main aspect, because four o'clock six gas differences, and human quality's difference, so Biao Xian syndrome has the card of the double folder of wind and cold, wind heat and heat-damp in summer clinically.In the course of disease and the conversion of visible cold and heat or mixed.It is dry to experience wind heat summer-heat, and then the fur catharsis is not smooth, and pathogenic heat are violated lung, impairment of purifying function of the lung.As when experiencing row epidemic disease poison then how heavier the state of an illness is.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind of treatment heat-clearing and toxic substances removing, dispelling wind to relieve the exterior syndrome.Be used for medicine of wind-heat cold and preparation method thereof.This curative effect of medication is definite, and effect has no side effect taking convenience rapidly.
The inventor of Department of Pharmacy of the present invention is according to theory of Chinese medical science and the compound Chinese medicinal preparation that develops through for many years clinical empirical summary, and sheet is led in general sense by name.Medicine of the present invention is to be prepared from by acceptable excipient on the raw material of Chinese medicine of following weight parts and the pharmaceutics:
Flos Lonicerae 70-130 Folium Isatidis 40-90 Radix Isatidis 38-90
Fructus Gardeniae 25-85 Herba Houttuyniae 15-60 Radix Glycyrrhizae 8-45
The traditional Chinese medical science thinks, flu is because six climate exopathogens, the time row virus attack human body and causing a disease.Clinical multilist is existing to be its feature with nasal obstruction, watery nasal discharge, sneeze, cough, headache, aversion to cold, heating, general malaise etc.Ailment said due to cold or exposure is first of the six climate exopathogens, generally with wind and cold, wind heat both for seeing more.Characteristic of the wind being light and upward, Jiao that goes against one's superiors more, so " element asks lunar sun a bright opinion piece of writing " said: " hinder in the wind person, on be subjected to it earlier." the lung place in the heart, be positioned at the part of the body cavity above the diaphragm housing the heart and lungs, the main breathing, air flue for the path of the lifting of coming in and going out, larynx for it is, has one's ideas straightened out in nose, closes fur outward, be in charge of defend outside.So exopathogen is from mouth and nose, fur invasion, lung is defended and is stood in the breach, and after the sense heresy, occurs defending the table and the part of the body cavity above the diaphragm housing the heart and lungs symptom of lung system very soon.
Wind heat is violated table, and the heat stagnation flesh natural fibre line of meat is defended table and become estranged, thus see that fever of the body is heavier, micro evil wind, sweating is not smooth, distending pain in the head, cough, expectorant glues or is yellow, parched throat and ache cards such as thirst with desire to drink.As being widely current in a period, syndrome is heterogeneous to be called influenza like the person, and certain infectiousness is arranged, and the sickness rate height has considerable influence to people ' s health and work, therefore must active treatment.Treatment is worked as with relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, the method for heat-clearing and toxic substances removing.
Monarch drug: Flos Lonicerae.This product is cold in nature, and its flower can be evacuated again, the kind heat-clearing and toxic substances removing of the merit pathogenic factor in the exterior that can loose thoroughly of holding concurrently, be usually used in affection due to external wind and heat or epidemic febrile disease from the beginning of.
Ministerial drug: Folium Isatidis, Radix Isatidis.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, heat clearing away in Great Cold, the bitter in the mouth drop-down, merit is apt to heat-clearing and toxic substances removing, and can QI and blood and the exterior and the interior two clear.And bitter cold is arranged and not dry, the length of the moon is not decreased in heat clearing away, is used for outer flu wind heat or epidemic febrile disease from the beginning of the heavier person of pathogenic heat.Folium Isatidis, Radix Isatidis are leaf and the root of same plant, act on closely, and the effect of Folium Isatidis clearing away heat and cooling blood is stronger, and the Radix Isatidis then power of eliminating stagnation sore-throat relieving is more excellent.The two can strengthen the power of Flos Lonicerae heat-clearing and toxic substances removing.
Adjuvant drug: Fructus Gardeniae, the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the relieving restlessness that clears away heart-fire is longer than in removing pathogenic heat from blood and toxic substance from the body, the clear exterior heat of holding concurrently.Herba Houttuyniae: the hot evacuation of pus of loosing of this product, cold then heat-clearing and toxic substances removing is the key medicine for the treatment of lung abscess.Be used for the heap soil or fertilizer over and around the roots of expectorant heat and stagnate, the merit of inducing diuresis for treating stranguria syndrome is also arranged, but pathogenic fire purging is descending in the card of lung.
Messenger drug: Radix Glycyrrhizae, detoxify and coordinating the actions of various ingredients in a prescription.
Above-mentioned all medicines share has heat-clearing and toxic substances removing, the effect of relieving the exterior syndrome with drugs of pungent in flavor and cool in nature.Flos Lonicerae:
" Mingyi Bielu ": " cold and heat, body swell pyretic toxicity ".
Jing-Yue Complete Works: " Flos Lonicerae, kind removing toxic substances is controlled carbuncle, toxic swelling, the skin ulcer tinea, all poison of rheumatism really are key medicine.”
[modern study]
1, pharmacology: broad-spectrum antibacterial action is arranged, antiinflammatory action etc.
2, clinical: as 1. to be used for appendicitis, abscess of appendix.2. being used for flu, is the Lonicerae and Forsythiae Powder treatment diseases caused by exogenous pathogenic factor of principal agent with the Flos Lonicerae, and curative effect is better.3. be used to prevent upper respiratory tract infection.
Folium Isatidis:
[book on Chinese herbal medicine is collected]
" Mingyi Bielu ": " treat the seasonal epidemic pathogens headache, big heat, aphtha.”
Jing-Yue Complete Works: " control the pestilence pyretic toxicity and go mad, the wind heat macule ....”
" book on Chinese herbal medicine meets former ": " Folium Isatidis, eliminating pathogen in the liver gallbladder excess-fire is just with the pathogenic heat of the heart stomach of dispelling.”
[modern study]
1, pharmacology: broad-spectrum antiseptic and antivirus action are arranged; Have analgesic and antiinflammatory action; And can strengthen the phagocytic power of leukocyte to antibacterial.
2, clinical: be used for upper respiratory tract infection, measles and pneumonia infection is used for encephalitis b.Herba Houttuyniae:
[book on Chinese herbal medicine is collected]
" the southern regions of the Yunnan Province book on Chinese herbal medicine ": " control lung abscess cough band pus and blood, expectorant has stench.”
[modern study]
1, pharmacology: broad-spectrum antibacterial action is arranged; Can raise immunity.
2, clinical: be used for the treatment of pneumonia, the treatment chronic tracheitis is used for the treatment of upper respiratory tract infection and other class diseases.
The weight portion proportion optimization of raw material of Chinese medicine of the present invention:
Flos Lonicerae 70 Folium Isatidiss 40 Radix Isatidiss 38
Fructus Gardeniae 25 Herba Houttuyniae 15 Radix Glycyrrhizaes 8
The weight portion proportioning of above-mentioned raw materials medicine is also preferred:
Flos Lonicerae 100 Folium Isatidiss 60 Radix Isatidiss 60
Fructus Gardeniae 50 Herba Houttuyniae 30 Radix Glycyrrhizaes 20
The weight portion proportioning of above-mentioned raw materials medicine is also preferred:
Flos Lonicerae 115 Folium Isatidiss 75 Radix Isatidiss 75
Fructus Gardeniae 70 Herba Houttuyniae 45 Radix Glycyrrhizaes 35
The weight portion proportioning of above-mentioned raw materials medicine is also preferred:
Flos Lonicerae 130 Folium Isatidiss 90 Radix Isatidiss 90
Fructus Gardeniae 85 Herba Houttuyniae 60 Radix Glycyrrhizaes 45
Medicine of the present invention can be carried according to the conventional method such as the water of this area, alcohol extraction etc. is prepared into acceptable oral preparation dosage form on any pharmaceutics.Wherein preferred capsule, tablet, granule, powder or pill.
Medicine of the present invention also can be made by the method for being prepared as follows:
Above Six-element, extracting honeysuckle, Herba Houttuyniae add 8-12 times of water gaging, and steam distillation extracts volatile oil, and extraction time is 6-8 hour, and medicinal liquid device is in addition collected; Other gets 150g amount Radix Isatidis crushing fine powder, and is standby; Three flavors such as all the other 100g Radix Isatidis and Fructus Gardeniae merge, decoct with water 3-4 time, add water 6-10 doubly measures at every turn, decocted 1-2 hour, merge decoction liquor and extract the last medicinal liquid of volatile oil, filter, filtrate is concentrated into relative density 1.13-1.15 (60 ℃ of surveys), add ethanol and be 50-70%, static 20-24 hour, filter to containing the alcohol amount, filtrate recycling ethanol, and to be concentrated into relative density be that the thick paste of 1.30-1.35 (60 ℃) merges above-mentioned medicinal liquid, and technology is made acceptable oral preparation dosage form on the pharmaceutics routinely then, as capsule, tablet, granule, powder, or pill.
The preparation method of medicine of the present invention is preferred:
Above Six-element, extracting honeysuckle, Herba Houttuyniae add 10 times of water gagings, and steam distillation extracts volatile oil, and extraction time is 6 hours, and medicinal liquid device is in addition collected; Other gets 150g amount Radix Isatidis crushing fine powder, and is standby; Three flavors such as all the other 100g Radix Isatidis and Fructus Gardeniae merge, and decoct with water 3 times, add 8 times of amounts of water at every turn, decoct 1.5 hours, merge decoction liquor and extract the last medicinal liquid of volatile oil, filter, filtrate is concentrated into relative density 1.13-1.15 (60 ℃ of surveys), and adding ethanol is 60% to containing the alcohol amount, static 24 hours, filter filtrate recycling ethanol, and be concentrated into the thick paste that relative density is 1.30-1.35 (60 ℃), and even with above-mentioned fine powder, drying, pulverize, granulate, spray into volatile oil, mixing, tabletting, coating.
Promptly get tablet of the present invention
The logical sheet of sense has heat-clearing and toxic substances removing, relieving the exterior syndrome with drugs of pungent in flavor and cool in nature.Cure mainly the wind-heat syndrome of flu, it is more outstanding to show as fever of the body, micro evil wind, sweating is not smooth, distending pain in the head, cough, expectorant is sticking or yellow, parched throat pharyngalgia, or pharynx tonsillitis congestion and swelling pain, nasal obstruction, stream turbid nasal discharge, cards such as thirst with desire to drink, significant improvement effect is arranged, it is to blood, urine, just conventional, and liver, renal function also have no adverse effects, and do not see obvious adverse reaction.We think that the logical sheet of sense is a kind of heat-clearing and toxic substances removing safely and effectively, pungent and cold medicine for relieving the exterior syndrome.
Embodiment
Embodiment 1
Flos Lonicerae 70 Folium Isatidiss 40 Radix Isatidiss 38
Fructus Gardeniae 25 Herba Houttuyniae 15 Radix Glycyrrhizaes 8
Make capsule of the present invention according to a conventional method.
Embodiment 2
Flos Lonicerae 130 Folium Isatidiss 90 Radix Isatidiss 90
Fructus Gardeniae 85 Herba Houttuyniae 60 Radix Glycyrrhizaes 45
Make powder of the present invention according to a conventional method
Embodiment 3
Flos Lonicerae 115 Folium Isatidiss 75 Radix Isatidiss 75
Fructus Gardeniae 70 Herba Houttuyniae 45 Radix Glycyrrhizaes 35
Make granule of the present invention according to a conventional method.
Embodiment 4
Flos Lonicerae 100 Folium Isatidiss 60 Radix Isatidiss 60
Fructus Gardeniae 50 Herba Houttuyniae 30 Radix Glycyrrhizaes 20
Make pill of the present invention according to a conventional method.
Embodiment 5
Flos Lonicerae 100 Folium Isatidiss 60 Radix Isatidiss 60
Fructus Gardeniae 50 Herba Houttuyniae 30 Radix Glycyrrhizaes 20
Above Six-element, extracting honeysuckle, Herba Houttuyniae add 10 times of water gagings, and steam distillation extracts volatile oil, and extraction time is 6 hours, and medicinal liquid device is in addition collected; Other gets 150g amount Radix Isatidis crushing fine powder, and is standby; Three flavors such as all the other 100g Radix Isatidis and Fructus Gardeniae merge, decoct with water 3 times, add 8 times of amounts of water at every turn, decocted 1.5 hours, merge decoction liquor and extract the last medicinal liquid of volatile oil, filter, filtrate is concentrated into relative density 1.13-1.15 (60 ℃ of surveys), and adding ethanol is 60% to containing the alcohol amount, static 24 hours, filter, filtrate recycling ethanol, and be concentrated into the thick paste that relative density is 1.30-1.35 (60 ℃), even with above-mentioned fine powder, drying is pulverized, and granulates, spray into volatile oil, mixing, tabletting, coating. both got tablet of the present invention.
Claims (9)
1. treat heat-clearing and toxic substances removing for one kind, the relieving the exterior syndrome with drugs of pungent in flavor and cool in nature medicine is characterized in that it is the oral formulations that is prepared from by acceptable excipient on following weight parts Chinese medicinal raw materials and the pharmaceutics:
Flos Lonicerae 70-130 Folium Isatidis 40-90 Radix Isatidis 38-90
Fructus Gardeniae 25-85 Herba Houttuyniae 15-60 Radix Glycyrrhizae 8-45
2. medicine according to claim 1 is characterized in that the weight portion proportioning of raw material of Chinese medicine is:
Flos Lonicerae 70 Folium Isatidiss 40 Radix Isatidiss 38
Fructus Gardeniae 25 Herba Houttuyniae 15 Radix Glycyrrhizaes 8
3. medicine according to claim 1 is characterized in that the weight portion proportioning of raw material of Chinese medicine is:
Flos Lonicerae 100 Folium Isatidiss 60 Radix Isatidiss 60
Fructus Gardeniae 50 Herba Houttuyniae 30 Radix Glycyrrhizaes 20
4. medicine according to claim 1 is characterized in that the weight portion proportioning of raw material of Chinese medicine is:
Flos Lonicerae 115 Folium Isatidiss 75 Radix Isatidiss 75
Fructus Gardeniae 70 Herba Houttuyniae 45 Radix Glycyrrhizaes 35
5. medicine according to claim 1 is characterized in that the weight portion proportioning of raw material of Chinese medicine is:
Flos Lonicerae 130 Folium Isatidiss 90 Radix Isatidiss 90
Fructus Gardeniae 85 Herba Houttuyniae 60 Radix Glycyrrhizaes 45
6. according to each described medicine of claim 1-5, it is characterized in that: this medicine is capsule, tablet, granule, powder or pill.
7. according to each described medicine of claim 1-5, it is characterized in that: this medicine is a tablet
8. the preparation method of each described medicine of claim 1-5 is characterized in that comprising the following steps:
Above Six-element, extracting honeysuckle, Herba Houttuyniae add 8-12 times of water gaging, and steam distillation extracts volatile oil, and extraction time is 6-8 hour, and medicinal liquid device is in addition collected; Other gets 150g amount Radix Isatidis crushing fine powder, and is standby; Three flavors such as all the other 100g Radix Isatidis and Fructus Gardeniae merge, decoct with water 3-4 time, add water 6-10 doubly measures at every turn, decocted 1-2 hour, merge decoction liquor and extract the last medicinal liquid of volatile oil, filter, filtrate is concentrated into relative density 1.13-1.15 (60 ℃ of surveys), add ethanol and be 50-70%, static 20-24 hour, filter to containing the alcohol amount, filtrate recycling ethanol, and to be concentrated into relative density be that the thick paste of 1.30-1.35 (60 ℃) merges above-mentioned medicinal liquid, and technology is made acceptable oral preparation dosage form on the pharmaceutics routinely then, as capsule, tablet, granule, powder, or pill.
9, the preparation method of the described medicine of claim 8 is characterized in that comprising the following steps
Above Six-element, extracting honeysuckle, Herba Houttuyniae add 10 times of water gagings, and steam distillation extracts volatile oil, and extraction time is 6 hours, and medicinal liquid device is in addition collected; Other gets 150g amount Radix Isatidis crushing fine powder, and is standby; Three flavors such as all the other 100g Radix Isatidis and Fructus Gardeniae merge, and decoct with water 3 times, add 8 times of amounts of water at every turn, decoct 1.5 hours, merge decoction liquor and extract the last medicinal liquid of volatile oil, filter, filtrate is concentrated into relative density 1.13-1.15 (60 ℃ of surveys), and adding ethanol is 60% to containing the alcohol amount, static 24 hours, filter filtrate recycling ethanol, and be concentrated into the thick paste that relative density is 1.30-1.35 (60 ℃), and even with above-mentioned fine powder, drying, pulverize, granulate, spray into volatile oil, mixing, tabletting, coating.
Promptly get tablet of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510112994 CN1742890A (en) | 2005-10-18 | 2005-10-18 | Heat-clearing detoxicating diaphoresis wind-expelling medicine for treating wind-heat syndrome such as common cold, and preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510112994 CN1742890A (en) | 2005-10-18 | 2005-10-18 | Heat-clearing detoxicating diaphoresis wind-expelling medicine for treating wind-heat syndrome such as common cold, and preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1742890A true CN1742890A (en) | 2006-03-08 |
Family
ID=36138515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510112994 Pending CN1742890A (en) | 2005-10-18 | 2005-10-18 | Heat-clearing detoxicating diaphoresis wind-expelling medicine for treating wind-heat syndrome such as common cold, and preparation thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1742890A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112999288A (en) * | 2021-04-07 | 2021-06-22 | 一力制药股份有限公司 | Vitamin C honeysuckle and forsythia tablet and preparation method and application thereof |
-
2005
- 2005-10-18 CN CN 200510112994 patent/CN1742890A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112999288A (en) * | 2021-04-07 | 2021-06-22 | 一力制药股份有限公司 | Vitamin C honeysuckle and forsythia tablet and preparation method and application thereof |
| CN112999288B (en) * | 2021-04-07 | 2022-02-08 | 一力制药股份有限公司 | Traditional Chinese medicine tablet for treating viral influenza and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100344313C (en) | Chinese patent drug for treating infantile cold and repeated cold, and its prepn. method | |
| CN101049424B (en) | Medication for treating infection in respiratory system | |
| JP7560154B2 (en) | Compound formulations of Forsythia and Astragalus membranaceus and their manufacturing method and use | |
| CN1210047C (en) | Medicine for treating cold and preparation method thereof | |
| CN104491052B (en) | Traditional Chinese medicine composition for treating rheumatic and rheumatoid arthritis and preparation method thereof | |
| CN102526578B (en) | Granular medicine for treating cold | |
| CN104666559A (en) | Traditional Chinese medicine capsules for treating nasosinusitis | |
| CN101642501A (en) | Medicine used for wind heat disease of cold for clearing away heat and toxic materials, dispelling wind and relieving exterior syndrome and preparation method thereof | |
| CN116139237B (en) | A Chinese medicinal composition for preventing and treating respiratory tract infection caused by coronavirus, and its application | |
| CN1150927C (en) | Stomatopathy and throat disease treating health care medicine and its production process | |
| CN1317004C (en) | Chinese medicine prepn for treating infantile respiratory tract infection | |
| CN109316551A (en) | A kind of Chinese medicine composition and preparation method thereof for treating acpuei pharyngitis | |
| CN107496618A (en) | It is a kind of to treat flu, the Chinese medicine composition to generate heat and preparation method thereof | |
| CN102429980A (en) | Cold granules and preparation method thereof | |
| CN1742890A (en) | Heat-clearing detoxicating diaphoresis wind-expelling medicine for treating wind-heat syndrome such as common cold, and preparation thereof | |
| CN1350868A (en) | Medicine for preventing and treating cold and its preparing process | |
| CN102499977B (en) | Traditional Chinese medicine preparation for treating children bronchopneumonia | |
| CN1191086C (en) | Medicine for treating cold in summer and autumn | |
| CN102429982A (en) | Traditional Chinese medicine granules for treating cold and preparation method thereof | |
| CN103977313B (en) | Diuresis promoting and itching relieving pills and preparation method thereof | |
| CN105250435A (en) | Compound Chinese herbal medicine preparation for treating influenza and preparation method of compound Chinese herbal medicine preparation | |
| CN105055845A (en) | Medicine preparation for treating cardiac insufficiency | |
| CN106309596A (en) | Compound pure natural granule for treating cold and preparation method thereof | |
| CN105596581A (en) | Pharmaceutical preparation for treating human papilloma virus infection and preparation method and application of pharmaceutical preparation | |
| CN105106646A (en) | Medicinal preparation for treating chronic pharyngitis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |