CN1317004C - Chinese medicine prepn for treating infantile respiratory tract infection - Google Patents
Chinese medicine prepn for treating infantile respiratory tract infection Download PDFInfo
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- CN1317004C CN1317004C CNB2005100322646A CN200510032264A CN1317004C CN 1317004 C CN1317004 C CN 1317004C CN B2005100322646 A CNB2005100322646 A CN B2005100322646A CN 200510032264 A CN200510032264 A CN 200510032264A CN 1317004 C CN1317004 C CN 1317004C
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Abstract
The present invention relates to a Chinese medicine preparation for treating the respiratory tract infection of an infant, which is formed by that 8 to 12 shares of honeysuckle, 8 to 12 shares of forsythia fruit, 8 to 12 shares of bupleurum root, 8 to 12 shares of scutellaria, 8 to 12 shares of aster, 8 to 12 shares of dried orange peel, 8 to 12 shares of method summer, 8 to 12 shares of white peony root, 2 to 4 shares of glycyrrhiza and 5 to 8 shares of cassia twig are decocted in water and filtered. The present invention has the advantages of low raw material cost, wide material sources, simple preparation process and low production cost. The Chinese medicine preparation of the present invention is used for treating the respiratory tract infection of the infant and has the characteristics of short treatment course and obvious treatment effect.
Description
Technical field the present invention relates to the herbal mediciment preparation, specifically, provides a kind of herbal mediciment that is used for the treatment of infantile respiratory tract infection.
The background technology respiratory tract infection is clinical common disease, also is the most multiple the most common disease in children's's period, 90% above viral infection, and minority is bacterial infection or virus, bacteria mixed infection.The main way of current treatment infantile respiratory tract infection is to use antibiotic and antiviral drugs or treats by differential diagnosis in tcm choosing side.The former has the suspicion of abuse of antibiotics, and has certain toxicity.And the latter is longer many courses of treatment, and curative effect is not obvious.
Summary of the invention purpose of the present invention just is to provide a kind of herbal mediciment for the treatment of infantile respiratory tract infection, and its medicine source is wide, and cost is low, and curative effect is obvious rapidly.
Specifically, embodiment of the present invention are: a kind of herbal mediciment for the treatment of infantile respiratory tract infection, it is characterized in that, it is by the following preparation of raw material of making the weight portion of effective ingredient: Flos Lonicerae 8-12 part, Fructus Forsythiae 8-12 part, Radix Bupleuri 8-12 part, Radix Scutellariae 8-12 part, Radix Asteris 8-12 part, Pericarpium Citri Reticulatae 8-12 part, Rhizoma Pinelliae Preparatum 8-12 part, Radix Paeoniae Alba 8-12 part, Radix Glycyrrhizae 2-4 part and Ramulus Cinnamomi 5-8 part, these raw materials are fried in shallow oil 30-45 minute through boiling with 200-300 part hydrology fire, and filtration forms.
Be more effective realization the present invention, it is by the following preparation of raw material of making the weight portion of effective ingredient: 6 parts of 10 parts of Flos Loniceraes, 10 parts of Fructus Forsythiaes, 10 parts of Radix Bupleuri, 10 parts of Radix Scutellariaes, 10 parts of Radix Asteriss, 10 parts of Pericarpium Citri Reticulataes, 10 parts of Rhizoma Pinelliae Preparatum, 10 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae and Ramulus Cinnamomi.
The present invention can make dosage forms such as decoction, syrup, tablet, capsule, granule.The preparation method of described decoction is, with the sterilization of decoction filtering gained filtrate, bottled getting final product; The preparation method of described syrup is, adds monosaccharide or sucrose in gained filtrate, and addition is that every 100ml filtrate adds 15-20 gram monosaccharide or sucrose, and bottled then sterilization, capping form; The preparation method of described tablet is with gained medicinal liquid concentrate drying, adds starch, makes tablet; Described capsular preparation method is with gained medicinal liquid concentrate drying, incapsulates to form; The preparation method of described granule is with gained medicinal liquid concentrate drying, makes granule, packed.
The present invention is raw materials used cheap, wide material sources, and preparation method is simple and easy, and production cost is low, is used for the treatment of infantile respiratory tract infection, has short treating period, the tangible characteristics of curative effect.
The specific embodiment
Provide three implementation columns of the present invention below, each embodiment is raw materials used to see the following form:
The preparation method of embodiment 1 is: add 250ml water in raw material, slow fire boils fries in shallow oil 30-45 minute, filters, adds in gained filtrate monosaccharide or sucrose, addition is that every 100ml filtrate adds 15-20 gram monosaccharide or sucrose, bottling, vapor sterilization then, capping packing is made syrup.
The preparation method of embodiment 2 is: add 250ml water in raw material, slow fire boils fries in shallow oil 30-45 minute, filter, and bottling, vapor sterilization then, the capping packing is made decoction.
The preparation method of embodiment 3 is: add 250ml water in raw material, slow fire boils fries in shallow oil 30-45 minute, filters, and with gained medicinal liquid concentrate drying, incapsulates, and makes capsule.
The foregoing description filter medicinal liquid also can make granule through concentrate drying, packed, make granule.
Be checking therapeutic effect of the present invention, the present invention carries out clinical observation to it:
1, case is selected: select case by " practical paidonosology " diagnostic criteria.Course of disease 3-30 days (indivedual case courses of disease had 3-8 month to cough more than), 30 days-15 years old age, body temperature＜39 ℃, get rid of various tuberculosis, pleuritis and heart disease etc., the infant that belongs to non-specific respiratory tract infection (comprising virus or/and bacterial infection) is the object of observation, is divided into treatment group and matched group at random.
564 examples are organized in treatment, man, 293 examples (52%), women 271 examples (48%); 30 days-15 years old age, wherein 474 exceptions (accounting for 84%) below 7 years old.564 examples of coughing (100%), cough companion light Zhong chuan person's 84 examples (14.9%), hot 144 examples (25.5%) that occur together, two lungs have dried moist rale person's 402 examples (71.3%).
Matched group 420 examples, male 225 examples (53.6%), women 195 examples (46.4%); 60 days-15 years old age wherein was 350 examples (83.3%) below 7 years old.Cough person's 420 examples (100%), the companion is light, Zhong chuan person's 23 examples (5.5%), and hot person's 102 examples (24.3%) occur together; Two lungs have dried moist rale person's 302 examples (71.9%).
Two groups of clinical datas are learned processing by statistics, difference that there are no significant.(P＞0.05) two groups of case comparabilities are stronger.
2, Therapeutic Method: the treatment group is treated with pure Chinese medicine silver osmanthus soup.Form by medicines such as Flos Lonicerae, Fructus Forsythiae, Radix Scutellariae, Radix Asteris, Ramulus Cinnamomi, Rhizoma Pinelliae Preparatum, the Radix Paeoniae Alba, Radix Stemonae (processed), Radix Glycyrrhizae Preparata.Heating adds with Radix Bupleuri, Radix Puerariae person more than 38 ℃, and the companion person of breathing heavily adds Fructus Perillae, Semen Lepidii (Semen Descurainiae).Add tap water 100ml-120ml (every flavor dose restrains at 3-10 according to infant age size) 1 dose of every day, fries in shallow oil to 6-80ml.Infant divides in 4-6 time one day and takes, and older youngster divides in 3-4 time one day and takes.
The pure western medicine of matched group.Main medication has amoxicillin 50mg/kg/ time, and oral 4 times, or 100kg/kg/ time, quiet notes, every day 2 times; Virazole 5mg/kg/ time, 2 injections every day, or oral moroxydine 20mg/kg/ days, in a few days divide three times.Heating person lowers the temperature with acetaminophen; Breathe heavily that weight person adds aminophylline or nitrendipine is relievingd asthma.
3, result:
3.1 efficacy determination (being a course of treatment with three days all): clinical cure: cough disappears or idol is coughed, body temperature is normal, pulmonary's moist rale, the equal complete obiteration of wheezing sound.Produce effects: cough (a day not super 5-6 time) is arranged slightly, and body temperature is normal, and pulmonary's sign disappears substantially or hears a small amount of rale.Effectively: coughing or panting is clearly better, and body is wet normal, and pulmonary's sign obviously reduces.Invalid: as relatively not have obviously change before symptom and sign and the medication, even increase the weight of in addition.
3.2 two groups of curative effects relatively see Table 1:
Table 1 liang group curative effect is [example (%)] relatively
| Group | The example number | Recovery from illness | Produce effects | Effectively | Invalid | Effectively total |
| Treatment group matched group | 564 420 | 415(73.5) 229(54.5) | 92(16.4) 57(13.5) | 39(6.9) 43(10.4) | 18(3.2) 91(21.6) | 546(96.8) 329(78.3) |
Find out in the table that treatment by Chinese herbs group total effective rate is apparently higher than western medicine group.Through X
2, its X
2=8.123, there is the meaning of highly significant P＜0.01.
Relatively see Table 2 3.3 respectively organize the symptom and sign extinction time.Two groups of infant fever times similar (P＞0.05), and cough, asthma, do moist rale extinction time treatment group and be better than matched group.
Table 2 liang group symptom and sign extinction time comparison (my god)
| Group | Heating | Cough | Asthma | Do moist rale |
| Treatment group matched group | 1.1±1.02 1.24±1.08 | 2.45±0.07 5.60±2.24 | 2.76±1.09 3.28±1.81 | 3.13±1.45 5.24±2.25 |
Respectively through X
2Check is learnt; Bring down a fever and asthma regression time no significant difference (P＞0.05), but cough-relieving and dried moist rale regression time two groups all there were significant differences, Chinese drug-treated group all is better than the Western medicine group.Particularly antitussive action has been compared significant difference (P＜0.05) for two groups.
4, discuss: the present invention is theoretical according to the invasion of traditional Chinese medical science exopathogen, sums up a proved recipe that forms in conjunction with the clinical practice of author's more than two decades.We think: infantile respiratory tract infection mostly is the disease that virus or antibacterial are taken advantage of a weak point and cause when children's's Abwehrkraft des Koepers or immunoregulation capability descend, and belongs to the traditional Chinese medical science said " exopathogen invasion " more and falls ill.Because lung associating with skin and hair, lung opening at nose, throat communicates with lung, nose, is again the door of lung, thus on the sense whole respiratory tract of can stretching.Common performance has cough, coughs up phlegm, watery nasal discharge, nasal obstruction, fear of cold, heating.In Chinese traditional treatment, then uncharm to induce sweat, relieving cough and resolving phlegm, lung qi dispersing Dingchuan and heat-clearing and toxic substances removing.But Flos Lonicerae, Fructus Forsythiae, Radix Scutellariae heat-clearing and toxic substances removing in the side reach the purpose of anti-bacteria and anti-virus.Radix Scutellariae has the heat of letting out half lining clearly again, and Radix Bupleuri is the heresy of half table thoroughly, share the heresy that then can remove cold and heat with Radix Scutellariae.Just protect by eliminating evil with the Yang-freeing and Qi-boosting stomach function regulating with Rhizoma Pinelliae Preparata, Ramulus Cinnamomi, Radix Glycyrrhizae, the Radix Paeoniae Alba, lung qi dispersing is moisturized, preventing phlegm from forming and stopping coughing.Cold and heat are double to be controlled so this can carry out.Is to distinguish that respiratory tract infection system is caused by that quasi-microorganism, also just can't select antibiotic for use in basic unit with the doctor trained in Western medicine method.In addition up to the present, also virus do not had the obvious and effective medicine.And the existing antibacterium effect of many medicines in the Chinese medicine has antivirus action again, at this, has showed the superiority of Chinese medicine.
Simultaneously, we learn from practice: infantile respiratory tract infection person heat is easily moved back, and the expectorant difficulty is dispelled, and coughs difficult ending.Fever time no significant difference from two groups of cases, and cough ends variant susceptible of proof this point of time.Phlegm-damp is the source of touching primary disease often, and the lung network easily is stranded by phlegm-damp.Expectorant gas shutoff general rule causes hypopnea, and expectorant coagulates the lung road can cause cough, asthma, and the stagnant lung network of expectorant then causes phlegm retention and stagnates.Infantile respiratory tract infection mostly is due to the ailment said due to cold or exposure, so take strengthening vital QI to eliminate pathogenic factors, relieving cough and resolving phlegm, nourishing the lung to keep the adverse QI downward on the rule of treatment
[3]As aforementioned, Flos Lonicerae, Fructus Forsythiae, Radix Scutellariae have antiviral, antibacterial effect among the present invention, have reached the effect of removing the cause of disease.Ramulus Cinnamomi Radix Bupleuri mainly be relax the flesh diaphoresis, bring down a fever promote the production of body fluid, elevate a turnable ladder yang-energy, warming the meridian for promoting the flow of YANG QI.Radix Asteris then be the circulation of qi promoting of billows lung, relieving the exterior syndrome lung qi dispersing, relieving cough and asthma, therapeutic method to keep the adverse QI flowing downwards expectorant, circulation of qi promoting and in effect
[4]But the effect of Radix Glycyrrhizae invigorating the spleen and replenishing QI, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription has guaranteed with Ramulus Cinnamomi cold expelling, has made Radix Scutellariae and the magical effect of dispelling the heat.This side has reached clearing away lung-heat, cold, the comprehensive function evil, that change turbid expectorant, smooth lung qi, flat cough of dispelling the heat of dispeling the wind.Simultaneously this side have cough-relieving be regardless of new for a long time, warm and not dry, profit and oiliness, cold expelling does not help heat, induce sweat and be not harmful to the health, the characteristics that each one is all desirable.In the treatment group case of the present invention, most sick children only needed to prove effective in 1-2 days, and what the minority course of disease was long also only needs 4-6 days promptly.
Claims (6)
1, a kind of herbal mediciment for the treatment of infantile respiratory tract infection, it is characterized in that, it is by the following preparation of raw material of making the weight portion of effective ingredient: Flos Lonicerae 8-12 part, Fructus Forsythiae 8-12 part, Radix Bupleuri 8-12 part, Radix Scutellariae 8-12 part, Radix Asteris 8-12 part, Pericarpium Citri Reticulatae 8-12 part, Rhizoma Pinelliae Preparatum 8-12 part, Radix Paeoniae Alba 8-12 part, Radix Glycyrrhizae 2-4 part and Ramulus Cinnamomi 5-8 part, these raw materials are fried in shallow oil 30-45 minute through boiling with 200-300 part hydrology fire, and filtration forms.
2, the herbal mediciment of treatment infantile respiratory tract infection according to claim 1, it is characterized in that it is by the following preparation of raw material of making the weight portion of effective ingredient: 6 parts of 10 parts of Flos Loniceraes, 10 parts of Fructus Forsythiaes, 10 parts of Radix Bupleuri, 10 parts of Radix Scutellariaes, 10 parts of Radix Asteriss, 10 parts of Pericarpium Citri Reticulataes, 10 parts of Rhizoma Pinelliae Preparatum, 10 parts of the Radix Paeoniae Albas, 3 parts in Radix Glycyrrhizae and Ramulus Cinnamomi.
3, the herbal mediciment of treatment infantile respiratory tract infection according to claim 1 and 2, it is characterized in that, add monosaccharide or sucrose in filtering gained filtrate, addition is that every 100ml filtrate adds 15-20 gram monosaccharide or sucrose, syrup is made in bottled then sterilization, capping.
4, the herbal mediciment of treatment infantile respiratory tract infection according to claim 1 and 2 is characterized in that, will filter gained medicinal liquid concentrate drying, adds starch, makes tablet.
5, the herbal mediciment of treatment infantile respiratory tract infection according to claim 1 and 2 is characterized in that, will filter gained medicinal liquid concentrate drying, incapsulates, and makes capsule.
6, the herbal mediciment of treatment infantile respiratory tract infection according to claim 1 and 2 is characterized in that, will filter gained medicinal liquid concentrate drying, makes granule, and is packed, makes granule.
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| CNB2005100322646A CN1317004C (en) | 2005-10-18 | 2005-10-18 | Chinese medicine prepn for treating infantile respiratory tract infection |
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| CN1317004C true CN1317004C (en) | 2007-05-23 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102499966A (en) * | 2011-12-27 | 2012-06-20 | 许从玉 | Medicinal composition for treating recurrent respiratory tract infection (RRTI) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1883597B (en) * | 2006-06-13 | 2011-04-06 | 苏绍龙 | Quickly acting medicine for treating cold and cough |
| WO2014063290A1 (en) * | 2012-10-22 | 2014-05-01 | Jiang Tingyi | Oral solution for common cold |
| CN106109593A (en) * | 2016-08-11 | 2016-11-16 | 洛阳名力科技开发有限公司 | A kind of prevention and the medicinal liquid for the treatment of respiratory tract disease |
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| CN1215610A (en) * | 1998-10-16 | 1999-05-05 | 湖南正清制药集团股份有限公司 | Antipyretic and antitoxic particles and preparing method thereof |
| CN1377660A (en) * | 2001-03-30 | 2002-11-06 | 昆明市中医医院 | Medicine for curing bronchial asthma disease and its preparing method |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1215610A (en) * | 1998-10-16 | 1999-05-05 | 湖南正清制药集团股份有限公司 | Antipyretic and antitoxic particles and preparing method thereof |
| CN1377660A (en) * | 2001-03-30 | 2002-11-06 | 昆明市中医医院 | Medicine for curing bronchial asthma disease and its preparing method |
Non-Patent Citations (1)
| Title |
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| 常见中药名错误分析 李占永，中国民间疗法，第11卷第4期 2003 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102499966A (en) * | 2011-12-27 | 2012-06-20 | 许从玉 | Medicinal composition for treating recurrent respiratory tract infection (RRTI) |
| CN102499966B (en) * | 2011-12-27 | 2012-10-03 | 许从玉 | Medicinal composition for treating recurrent respiratory tract infection (RRTI) |
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