CN104288477A - Traditional Chinese medicine preparation curing infantile asthma - Google Patents

Traditional Chinese medicine preparation curing infantile asthma Download PDF

Info

Publication number
CN104288477A
CN104288477A CN201410593484.5A CN201410593484A CN104288477A CN 104288477 A CN104288477 A CN 104288477A CN 201410593484 A CN201410593484 A CN 201410593484A CN 104288477 A CN104288477 A CN 104288477A
Authority
CN
China
Prior art keywords
grams
radix
gram
chinese medicine
medicine preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410593484.5A
Other languages
Chinese (zh)
Inventor
王丽丽
李金军
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201410593484.5A priority Critical patent/CN104288477A/en
Publication of CN104288477A publication Critical patent/CN104288477A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/264—Aristolochia (Dutchman's pipe)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716—Clematis (leather flower)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888—Pinellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966—Fritillaria, e.g. checker lily or mission bells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

The invention discloses a traditional Chinese medicine preparation curing infantile asthma. The traditional Chinese medicine preparation comprises the following active ingredients in parts by weight: 10-15 g of radix rehmanniae preparata, 5-15 g of ginger processed pinellia, 5-15 g of flos farfarae, 5-10 g of schisandra chinensis, 5-15 g of liquorice, 5-15 g of henry clematis root, 3-5 g of gingo, 5-10 g of scutellaria baicalensis, 5-15 g of root of red-rooted salvia, 3-5 g of ephedra, 5-10 g of lumbricus, 3-9 g of thunberg fritillary bulb, 3-5 g of semen lepidii, 5-15 g of almond, 5-10 g of birthwort, 3-5 g of marsdenia longipes and 5-10 g of folium eriobotryae. The selected medicinal materials are excellent in compatibility, and play the function of relieving cough and asthma, regulating the flow of vital energy, eliminating phlegm clearing heat and moistening lung together to achieve the effects of strengthening the body resistance, eliminating pathogenic factors, invigorating health and improving disease resistance; the traditional Chinese medicine preparation is worthy of clinical promotion and application.

Description

A kind of Chinese medicine preparation for the treatment of infantile asthma
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine preparation can treating infantile asthma.
Background technology
Asthma is one of common respiratory tract disease of department of pediatrics.Think that asthma is the diseases associated with inflammation that a kind of chronic airway continues at present, many cells play an important role wherein, as lymphocyte, eosinophilic granulocyte, mastocyte etc., and increase with non-specific airway significant reaction, the one being main clinical characteristics with the high response of air flue (BHR) is many because of property disease, early stage asthma can be divided into (to have in 3 years old and pant according to the time of origin of panting, last till 6 years old stopping person), late asthma is (without panting in 3 years old, to the person that just occurs wheezing symptoms when 6 years old) and persistent asthma (pant in 3 years old, still continued there is symptom to 6 years old).
Main manifestations is panted and coughing fit for repeatedly reversible clinically, uncomfortable in chest, dyspnea, and these symptoms are often reversible, but also Weight variable is even lethally dies, thus to the control of asthma should with attention.Current medicine can not treating both the principal and secondary aspects of a disease, and larger to the side effect of children's, for removing the misery of the mind & body of patient, according to the principle of tcm syndrome differentiation and treatment, treating both the principal and the secondary aspects of a disease at the same time, we provide a kind of Chinese medicine preparation, be used for the treatment of infantile asthma and achieve satisfied effect.
Summary of the invention
Instant invention overcomes the technical deficiency existed in treatment infantile asthma at present, provide a kind of hurtless measure, evident in efficacy, cheap, patient compliance is higher, cure after the Chinese medicine preparation for the treatment of infantile asthma that not easily recurs.
The technical solution adopted in the present invention is:
Treat a Chinese medicine preparation for infantile asthma, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Radix Rehmanniae Preparata 10-15 gram, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5-15 gram, Flos Farfarae 5-15 gram, Fructus Schisandrae Chinensis 5-10 gram, Radix Glycyrrhizae 5-15 gram, Radix Clematidis Henryi 5-15 gram, Semen Ginkgo 3-5 gram, Radix Scutellariae 5-10 gram, Radix Salviae Miltiorrhizae 5-15 gram, Herba Ephedrae 3-5 gram, Pheretima 5-10 gram, Bulbus Fritillariae Thunbergii 3-9 gram, Semen Lepidii (Semen Descurainiae) 3-5 gram, Semen Armeniacae Amarum 5-15 gram, Fructus Aristolochiae 5-10 gram, Radix Marsdeniae Longipedis 3-5 gram, Folium Eriobotryae 5-10 gram.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
10 grams, Radix Rehmanniae Preparata, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5 grams, Flos Farfarae 5 grams, Fructus Schisandrae Chinensis 5 grams, 5 grams, Radix Glycyrrhizae, Cortex Mori 5 grams, Semen Ginkgo 3 grams, Radix Scutellariae 5 grams, Radix Salviae Miltiorrhizae 5 grams, 3 grams, Herba Ephedrae, Pheretima 5 grams, Bulbus Fritillariae Thunbergii 3 grams, Semen Lepidii (Semen Descurainiae) 3 grams, 5 grams, Semen Armeniacae Amarum, Fructus Aristolochiae 5 grams, Radix Marsdeniae Longipedis 3 grams, Folium Eriobotryae 5 grams.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
12 grams, Radix Rehmanniae Preparata, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 grams, Flos Farfarae 10 grams, Fructus Schisandrae Chinensis 8 grams, 10 grams, Radix Glycyrrhizae, Cortex Mori 10 grams, Semen Ginkgo 4 grams, Radix Scutellariae 8 grams, Radix Salviae Miltiorrhizae 10 grams, 4 grams, Herba Ephedrae, Pheretima 8 grams, Bulbus Fritillariae Thunbergii 6 grams, Semen Lepidii (Semen Descurainiae) 4 grams, 10 grams, Semen Armeniacae Amarum, Fructus Aristolochiae 8 grams, Radix Marsdeniae Longipedis 4 grams, Folium Eriobotryae 8 grams.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
15 grams, Radix Rehmanniae Preparata, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15 grams, Flos Farfarae 15 grams, Fructus Schisandrae Chinensis 10 grams, 15 grams, Radix Glycyrrhizae, Cortex Mori 15 grams, Semen Ginkgo 5 grams, Radix Scutellariae 10 grams, Radix Salviae Miltiorrhizae 15 grams, 5 grams, Herba Ephedrae, Pheretima 10 grams, Bulbus Fritillariae Thunbergii 9 grams, Semen Lepidii (Semen Descurainiae) 5 grams, 15 grams, Semen Armeniacae Amarum, Fructus Aristolochiae 10 grams, Radix Marsdeniae Longipedis 5 grams, Folium Eriobotryae 10 grams.
The instructions of taking of Chinese medicine preparation of the present invention is: after being mixed by the raw material Chinese medicine of above-mentioned weight proportion, 1 dose/day, every agent head decocts the 500ml that adds water, and warm fire boils 25 minutes, extracting juice 250ml; Two decoct the 300ml that adds water, and warm fire boils 20 minutes, extracting juice 150ml.Two decoct mixing, morning and evening decoction being taken hot after meal.15 doses was 1 course for the treatment of.
The raw material Chinese medicine of above-mentioned Chinese medicine preparation:
Radix Rehmanniae Preparata, sweet in the mouth, slightly warm in nature; Return liver, kidney channel.Have YIN nourishing of enriching blood, beneficial essence fills out effect of marrow.
Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), acrid in the mouth, warm in nature; Return spleen, stomach, lung meridian.There is warming middle-JIAO reduce phlegm, effect of stopping nausea and vomiting by lowering the adverse flow of QI.
Flos Farfarae, acrid in the mouth, micro-hardship, warm in nature; Return lung meridian.There is nourishing the lung to keep the adverse QI downward, effect of relieving cough and resolving phlegm.
Fructus Schisandrae Chinensis, sour in the mouth, sweet, warm in nature; Return lung, the heart, kidney channel.There is convergence astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, effect of kidney calming.
Radix Glycyrrhizae, sweet in the mouth, property is put down; GUIXIN, lung, spleen, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.
Radix Clematidis Henryi, has heat-clearing and toxic substances removing, effect of eliminating phlegm and relieving cough.
Semen Ginkgo, sweet in the mouth, hardship, puckery, property is put down, poisonous; Return lung, kidney channel.There is astringing lung QI for relieving asthma, effect of leukorrhagia stopping reducing urination.
Radix Scutellariae, bitter in the mouth, cold in nature; Return lung, gallbladder, spleen, large intestine, small intestine meridian.There is heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive effect.
Radix Salviae Miltiorrhizae, bitter in the mouth, cold nature; GUIXIN, Liver Channel.Have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.
Herba Ephedrae, acrid in the mouth, micro-hardship, warm in nature; Return lung, urinary bladder channel.There is diaphoresis cold expelling, depressed lung-energy dispersing, effect of inducing diuresis to remove edema.
Pheretima, salty in the mouth, cold in nature; Return liver, spleen, urinary bladder channel.Have heat clearing away arresting convulsion, dredging collateral, relievings asthma, effect of diuresis.
Bulbus Fritillariae Thunbergii, bitter in the mouth, cold in nature; Return lung, heart channel.There is clearing heat, eliminating phlegm, relieving cough, effect of detoxicating and resolving stagnation of pathogens eliminating carbuncle.
Semen Lepidii (Semen Descurainiae), acrid in the mouth, hardship, property Great Cold; Return lung, urinary bladder channel.There is eliminating pathogen from the lung for relieving asthma, effect of line water detumescence.
Semen Armeniacae Amarum, bitter in the mouth, slightly warm in nature, slightly poisonous; Return lung, large intestine channel.There is sending down the abnormal ascending QI relieving cough and asthma, effect of loosening bowel to relieve constipation.
Fructus Aristolochiae has effect of lung heat clearing sending down the abnormal ascending QI, relieving cough and asthma.
Radix Marsdeniae Longipedis promoting blood circulation and hemostasis, relieving cough and asthma.For traumatic injury, rheumatalgia, internal hemorrhage, bronchitis, the diseases such as asthma.
Folium Eriobotryae is bitter, is slightly cold, returns lung, stomach warp, Folium Eriobotryae extractum, have the effects such as heat clearing away, lung moistening, relieving cough and resolving phlegm; Leaf decoct is containing saponin, amygdaloside, maloic acid, oleanolic acid, tannin, vitamin B l, vitamin C etc., and the hydrocyanic acid that contained amygdalin is hydrolyzed generation in vivo has antitussive action.Water decoction or ethyl acetate extract eliminate the phlegm and antiasthmatic effect.Volatile oil contained by its leaf has slight phlegm-dispelling functions.Also have report to point out, Folium Eriobotryae antitussive action is strong; Water decoction or ethyl acetate extract all have antibacterial action to white or staphylococcus aureus, Diplococcus pneumoniae, shigella flexneri.
The traditional Chinese medical science is thought and is caused the reason of infantile asthma to have two aspects, and one is endogenous cause of ill: because Lungs of Children splenic cord is empty, lungs are tender and lovely, defend outer ability, and skin space between skin and muscles is not fine and close, easy being invaded by exogenous pathogen.The heresy of wind and cold, wind heat invades human body by fur or mouth and nose, hinders in lung network, makes a surname of lung send out malfunction, disturbance of lung-QI, and body fluid cohesion is expectorant.Deficiency of spleen-QI, transporting ability, raw wet wine expectorant, above stores in lung.So ancient medicine has saying of " the spleen being the source of producing phlegm, the lung being the utensil for storing phlegm ".Two is exopathogenic factors, and owing to waiting cold temperature cataclysm, pathogen is taken advantage of a weak point, and heresy enters lung meridian priming latent phlegm, causes stagnation of phlegm air flue, QI rising in reverse order rale and be asthma.In general, asthma interior is because latent phlegm, and outer because diseases caused by exogenous pathogenic factor, endogenous cause of ill causes symptom by exopathogenic factor.Therefore treat primary disease to show according to patient's different symptoms, with relieving cough and relieving asthma, regulate the flow of vital energy and eliminate the phlegm, dialectical treatment, applies in a flexible way, and Fang Xianqi is imitated.
In Chinese medicine preparation of the present invention, Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis, Radix Glycyrrhizae beneficial essence can fill out marrow, supplementing QI for promoting the production of body fluid; Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Flos Farfarae, Radix Glycyrrhizae, Bulbus Fritillariae Thunbergii, Semen Armeniacae Amarum, Fructus Aristolochiae can relieving cough and resolving phlegm, clearing heat and moistening lung; Radix Clematidis Henryi, Semen Ginkgo, Radix Scutellariae, Radix Salviae Miltiorrhizae, Herba Ephedrae, Pheretima, Semen Lepidii (Semen Descurainiae) can depressed lung-energy dispersing, heat clearing away cold expelling; Radix Marsdeniae Longipedis promoting blood circulation and hemostasis, relieving cough and asthma; Folium Eriobotryae anti-inflammation, clearing and antitussive.Full side's compatibility is superior, attack benefit to execute mutually, treating both the principal and secondary aspects of a disease, give full play to the advantage that differential diagnosis in tcm treats, be used for the treatment of infantile asthma, there is relieving cough and asthma, regulate the flow of vital energy eliminate the phlegm, anti-inflammation, clearing heat and moistening lung merit, to reach the effect of strengthening vital QI to eliminate pathogenic factors, health invigorating, raising autoimmunity and resistance against diseases, clinic promotion and application.
For investigating clinical efficacy and the safety of medicine of the present invention further, we select the routine out-patient of certain hospital 40 to carry out clinical trial, are all women; Minimum 1.5 years old of age, maximum 8 years old, average 5 years old; The course of disease is the shortest 0.5 year, the longest 5 years, average 3.5 years; Early stage asthmatic patient 15 example, late asthma patient 13 example, persistent asthma patient 12 example.
Criterion of therapeutical effect:
Cure: clinical symptoms, sign disappear.
Effective: clinical symptoms, sign obviously alleviate.
Effective: clinical symptoms, sign slightly alleviated.
Invalid: clinical symptoms, sign all remain unchanged, do not improve completely.
Therapeutic Method:
After being mixed by the raw material Chinese medicine of above-mentioned weight proportion, add water fried, every agent head decocts the 500ml that adds water, and warm fire boils 25 minutes, extracting juice 250ml; Two decoct the 300ml that adds water, and warm fire boils 20 minutes, extracting juice 150ml.Two decoct mixing, every day 1 dose, point morning and evening 2 decoction being taken hot.15 doses was 1 course for the treatment of.
Efficacy result:
1. clinical efficacy result:
After treatment, cure 22 examples, effective 11 examples, effective 4 examples, invalid 3 examples; Cure rate 55%, obvious effective rate 27.5%, effective percentage 10%, inefficiency 7.5%, total effective rate 92.5%.Detailed results is in table 1.
Table 1: clinical efficacy result table after treatment
Number of cases Cure n (%) Effective n (%) Effective n (%) Invalid n (%) Effective percentage n (%)
40 22(55) 11(27.5) 4(10) 3(7.5) 37(92.5)
2. classifying type disease efficacy result:
After treatment, statistics finds, early stage asthmatic patient treated effect is 93.3%, late asthma treated effect is 92.3%, persistent asthma patient treatment effective percentage is 88.6%, can find out that Chinese medicine preparation of the present invention is in treatment infantile asthma, curative effect is early stage asthma > late asthma > persistent asthma.Detailed results is in table 2.
Table 2: classifying type disease efficacy result synopsis
Disease title Number of cases n Cure n Effective n Effective n Invalid n Effective percentage (%)
Early stage asthma 15 9 3 2 1 93.3
Late asthma 13 6 4 2 1 92.3
Persistent asthma 12 7 4 0 1 91.7
3. side effect reaction
In the treatment, all there is not obvious adverse reaction in all patients.
Result shows, Chinese medicine preparation of the present invention, by Chinese medicine differential diagnosis of diseases and the dialectical principle combined, is attacked to mend and doublely to be made, treating both the principal and the secondary aspects of a disease at the same time, is used for the treatment of that infantile asthma is evident in efficacy, cure rate is high and not easily recurs, having certain advantage, clinic promotion and application.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine preparation for the treatment of infantile asthma, chooses 10 grams, Radix Rehmanniae Preparata, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5 grams, Flos Farfarae 5 grams, Fructus Schisandrae Chinensis 5 grams, 5 grams, Radix Glycyrrhizae, Radix Clematidis Henryi 5 grams, Semen Ginkgo 3 grams, Radix Scutellariae 5 grams, Radix Salviae Miltiorrhizae 5 grams, 3 grams, Herba Ephedrae, Pheretima 5 grams, Bulbus Fritillariae Thunbergii 3 grams, Semen Lepidii (Semen Descurainiae) 3 grams, 5 grams, Semen Armeniacae Amarum, Fructus Aristolochiae 5 grams, Radix Marsdeniae Longipedis 3 grams, Folium Eriobotryae 5 grams.
Embodiment 2: a kind of Chinese medicine preparation for the treatment of infantile asthma, chooses 12 grams, Radix Rehmanniae Preparata, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 grams, Flos Farfarae 10 grams, Fructus Schisandrae Chinensis 8 grams, 10 grams, Radix Glycyrrhizae, Radix Clematidis Henryi 10 grams, Semen Ginkgo 4 grams, Radix Scutellariae 8 grams, Radix Salviae Miltiorrhizae 10 grams, 4 grams, Herba Ephedrae, Pheretima 8 grams, Bulbus Fritillariae Thunbergii 6 grams, Semen Lepidii (Semen Descurainiae) 4 grams, 10 grams, Semen Armeniacae Amarum, Fructus Aristolochiae 8 grams, Radix Marsdeniae Longipedis 4 grams, Folium Eriobotryae 8 grams.
Embodiment 3: a kind of Chinese medicine preparation for the treatment of infantile asthma, chooses 15 grams, Radix Rehmanniae Preparata, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15 grams, Flos Farfarae 15 grams, Fructus Schisandrae Chinensis 10 grams, 15 grams, Radix Glycyrrhizae, Radix Clematidis Henryi 15 grams, Semen Ginkgo 5 grams, Radix Scutellariae 10 grams, Radix Salviae Miltiorrhizae 15 grams, 5 grams, Herba Ephedrae, Pheretima 10 grams, Bulbus Fritillariae Thunbergii 9 grams, Semen Lepidii (Semen Descurainiae) 5 grams, 15 grams, Semen Armeniacae Amarum, Fructus Aristolochiae 10 grams, Radix Marsdeniae Longipedis 5 grams, Folium Eriobotryae 10 grams.
Below by concrete case, Chinese medicine preparation curative effect of the present invention is verified further:
Case 1
Xiao, female, 5 years old.Within 2 years, cause flu causes trouble bronchial asthma.Afterwards, asthma attack during flu at ordinary times, asthma, had no interest asymptomatic.Occasionally there is nocturnal cough.Remove hospital's western medical treatment, doctor allows and takes fluticasone propionate vapor and add Singulair oral (for a long time), about the 1 year time of medication, poor effect, simultaneously unfavorable to children's because worrying this type of hormonal medicaments, take Chinese medicine preparation of the present invention upon somebody's introduction and treat, take medicine 30 doses, without uncomfortable.Serve on 2 months, symptom all disappears.Follow up a case by regular visits to 1 year without recurrence.
Case 2
Cao, man, 3 years old.Infant cough with asthma repeatedly usually, heating, often the monthly hospital that will arrive treats, and the head of a family is also tired of by it deeply, and for eliminating misery as early as possible, through linking up with the head of a family, take this Chinese medicine preparation voluntarily, take medicine 3 courses for the treatment of, symptom obviously alleviates, and consolidation is taken medicine a course for the treatment of, transference cure.Follow up a case by regular visits to and do not recur for 1 year.
Case 3
Flood so-and-so, man, 7 years old.Nearly 5 years of Asthma recurrent exerbation, whenever cool rear outbreak, night is particularly evident, and companion's nasal obstruction, sneeze, even dyspnea during asthma attack, each outbreak continues half an hour more than.All do not alleviate through many hospitalizes.Upon somebody's introduction, to taking Chinese medicine preparation of the present invention, after 4 courses for the treatment of of taking medicine, readme symptom obviously alleviates, and continues to take 3 months altogether, transference cure with medicine of the present invention.Follow up a case by regular visits to and have no recurrence in 2 years.

Claims (4)

1. treat a Chinese medicine preparation for infantile asthma, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Radix Rehmanniae Preparata 10-15 gram, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5-15 gram, Flos Farfarae 5-15 gram, Fructus Schisandrae Chinensis 5-10 gram, Radix Glycyrrhizae 5-15 gram, Radix Clematidis Henryi 5-15 gram, Semen Ginkgo 3-5 gram, Radix Scutellariae 5-10 gram, Radix Salviae Miltiorrhizae 5-15 gram, Herba Ephedrae 3-5 gram, Pheretima 5-10 gram, Bulbus Fritillariae Thunbergii 3-9 gram, Semen Lepidii (Semen Descurainiae) 3-5 gram, Semen Armeniacae Amarum 5-15 gram, Fructus Aristolochiae 5-10 gram, Radix Marsdeniae Longipedis 3-5 gram, Folium Eriobotryae 5-10 gram.
2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
10 grams, Radix Rehmanniae Preparata, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 5 grams, Flos Farfarae 5 grams, Fructus Schisandrae Chinensis 5 grams, 5 grams, Radix Glycyrrhizae, Radix Clematidis Henryi 5 grams, Semen Ginkgo 3 grams, Radix Scutellariae 5 grams, Radix Salviae Miltiorrhizae 5 grams, 3 grams, Herba Ephedrae, Pheretima 5 grams, Bulbus Fritillariae Thunbergii 3 grams, Semen Lepidii (Semen Descurainiae) 3 grams, 5 grams, Semen Armeniacae Amarum, Fructus Aristolochiae 5 grams, Radix Marsdeniae Longipedis 3 grams, Folium Eriobotryae 5 grams.
3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
12 grams, Radix Rehmanniae Preparata, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 grams, Flos Farfarae 10 grams, Fructus Schisandrae Chinensis 8 grams, 10 grams, Radix Glycyrrhizae, Radix Clematidis Henryi 10 grams, Semen Ginkgo 4 grams, Radix Scutellariae 8 grams, Radix Salviae Miltiorrhizae 10 grams, 4 grams, Herba Ephedrae, Pheretima 8 grams, Bulbus Fritillariae Thunbergii 6 grams, Semen Lepidii (Semen Descurainiae) 4 grams, 10 grams, Semen Armeniacae Amarum, Fructus Aristolochiae 8 grams, Radix Marsdeniae Longipedis 4 grams, Folium Eriobotryae 8 grams.
4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
15 grams, Radix Rehmanniae Preparata, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 15 grams, Flos Farfarae 15 grams, Fructus Schisandrae Chinensis 10 grams, 15 grams, Radix Glycyrrhizae, Radix Clematidis Henryi 15 grams, Semen Ginkgo 5 grams, Radix Scutellariae 10 grams, Radix Salviae Miltiorrhizae 15 grams, 5 grams, Herba Ephedrae, Pheretima 10 grams, Bulbus Fritillariae Thunbergii 9 grams, Semen Lepidii (Semen Descurainiae) 5 grams, 15 grams, Semen Armeniacae Amarum, Fructus Aristolochiae 10 grams, Radix Marsdeniae Longipedis 5 grams, Folium Eriobotryae 10 grams.
CN201410593484.5A 2014-10-29 2014-10-29 Traditional Chinese medicine preparation curing infantile asthma Pending CN104288477A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410593484.5A CN104288477A (en) 2014-10-29 2014-10-29 Traditional Chinese medicine preparation curing infantile asthma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410593484.5A CN104288477A (en) 2014-10-29 2014-10-29 Traditional Chinese medicine preparation curing infantile asthma

Publications (1)

Publication Number Publication Date
CN104288477A true CN104288477A (en) 2015-01-21

Family

ID=52308588

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410593484.5A Pending CN104288477A (en) 2014-10-29 2014-10-29 Traditional Chinese medicine preparation curing infantile asthma

Country Status (1)

Country Link
CN (1) CN104288477A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104623217A (en) * 2015-02-06 2015-05-20 伦雪洁 Traditional Chinese medicine preparation for treating asthma and preparation method thereof
CN104645003A (en) * 2015-01-29 2015-05-27 崔银方 Traditional Chinese medicine preparation for treating asthma and preparation method of traditional Chinese medicine preparation
CN105125838A (en) * 2015-10-10 2015-12-09 临沂草之美医药科技有限公司 Traditional Chinese medicine composite for treating infantile asthma and preparing method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101229236A (en) * 2008-02-25 2008-07-30 北京金方华医药科技有限公司 Relieve asthma oral liquid preparation and preparing method thereof
US20080249143A1 (en) * 2003-03-26 2008-10-09 Fredrik Nicklasson New formulations and use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080249143A1 (en) * 2003-03-26 2008-10-09 Fredrik Nicklasson New formulations and use thereof
CN101229236A (en) * 2008-02-25 2008-07-30 北京金方华医药科技有限公司 Relieve asthma oral liquid preparation and preparing method thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
刘美凤等: "中药配伍对马兜铃毒性成分马兜铃酸A含量的影响", 《时珍国医国药》 *
国家食品药品监督管理总局: "关于加强广防己等6种药材及其制剂监督管理的通知 国食药监注[2004]379号", 《HTTP://WWW.SFDA.GOV.CN/WS01/CL0844/10242.HTML》 *
国家食品药品监督管理总局: "药品不良反应信息通报（第6期） 警惕含马兜铃酸中药的安全性问题、左旋咪唑等咪唑类驱虫药与脑炎综合征、盐酸芬氟拉明的心血管系统严重不良反应", 《HTTP://WWW.SDA.GOV.CN/WS01/CL0078/11278.HTML》 *
赖忆等: "中西医结合治疗支气管哮喘30例临床疗效观察", 《中华中西医杂志》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104645003A (en) * 2015-01-29 2015-05-27 崔银方 Traditional Chinese medicine preparation for treating asthma and preparation method of traditional Chinese medicine preparation
CN104623217A (en) * 2015-02-06 2015-05-20 伦雪洁 Traditional Chinese medicine preparation for treating asthma and preparation method thereof
CN105125838A (en) * 2015-10-10 2015-12-09 临沂草之美医药科技有限公司 Traditional Chinese medicine composite for treating infantile asthma and preparing method thereof

Similar Documents

Publication Publication Date Title
CN102940832B (en) Medicament for treating chronic bronchitis and preparation method thereof
CN104352587A (en) Ointment for treating rhinitis
CN103055260A (en) Traditional Chinese medicine composition for treating ulcerative colitis and preparation method thereof
CN102078462A (en) Asthma relieving medicament
CN104288477A (en) Traditional Chinese medicine preparation curing infantile asthma
CN104940485A (en) Traditional Chinese medicine composition for treating infantile asthma and preparation method thereof
CN102688384B (en) Traditional Chinese medicine decoction for treating chronic pharyngitis
CN106606719A (en) Traditional Chinese medicine used for treating chronic cough
CN103142733B (en) Chinese medicine composition for treating upper respiratory infection
CN104306793A (en) Chinese herba preparation for treating lobar pneumonia
CN103610915A (en) Traditional Chinese medicine for treating swelling and pain in throat
CN104491825B (en) A kind of Chinese medicine ointment for the treatment of oral ulcer
CN103349743A (en) Traditional Chinese medicine preparation for treating epistaxis
CN103142965A (en) Traditional Chinese medicine preparation for treating cold drink type children bronchial asthma
CN102784378A (en) Traditional Chinese medicine preparation for treating sub-health
CN104107344A (en) Traditional Chinese medicine composition for treating chronic bronchitis
CN103536673B (en) Topical powder with strong enhanced immunity for removing food retention, bringing down fever and relieving cough and asthma, and application thereof
CN103623161A (en) Traditional Chinese medicine formula for treating chronic bronchitis
CN104173716A (en) Traditional Chinese medicine decoction treating acute and chronic pharyngitis
CN103623369B (en) A kind of Chinese medicinal formulae for the treatment of tonsillitis, chronic pharyngitis
CN103142989B (en) Traditional Chinese medicine composition for treating infantile cough and preparation method thereof
CN106474405A (en) A kind of Chinese medicine formula treating cough
CN106620266A (en) Traditional Chinese medicine composition for treating mycoplasmal pneumonia of swine
CN104189815A (en) Traditional Chinese medicine preparation for treating children bronchial asthma
CN104740408A (en) Traditional Chinese medicine composition for treating pharyngitis

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20150121

WD01 Invention patent application deemed withdrawn after publication