CN1350868A - Medicine for preventing and treating cold and its preparing process - Google Patents
Medicine for preventing and treating cold and its preparing process Download PDFInfo
- Publication number
- CN1350868A CN1350868A CN 01129082 CN01129082A CN1350868A CN 1350868 A CN1350868 A CN 1350868A CN 01129082 CN01129082 CN 01129082 CN 01129082 A CN01129082 A CN 01129082A CN 1350868 A CN1350868 A CN 1350868A
- Authority
- CN
- China
- Prior art keywords
- flos
- radix
- medicine
- flos chrysanthemi
- heat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
A Chinese medicine for preventing and treating cold and heat shock is prepared from 7 Chinese-medicinal materials including honeysuckle flower, wild sesame, chrysanthemum flower, etc through proportioning, extracting, depositing in alcohol and preparing particles, syrup, oral liquid, tablets, or oncapsules. It has high curative effect.
Description
One, technical field
The present invention relates to a kind of medicine of preventing and treating affection due to external wind and heat, particularly relate to and prevent and treat the ripe flu that causes of diseases caused by exogenous pathogenic factor wind, cough, pharyngolaryngitis, urinary tract infection, and the medicine of sunstroke prevention, specifically Chinese herbal medicine is the Chinese patent medicine of feedstock production; The invention still further relates to the preparation method of this medicine.
Two, prior art
Affection due to external wind and heat belongs to a kind of disease " card " of Chinese medicine, belongs to the upper respiratory tract infection of modern medicine.Commonly encountered diseases is because of being to be caused by antibacterial that by virus, minority virus mainly is influenza virus (first, second, third), parainfluenza virus, respiratory syncytial virus, adenovirus etc., and bacterial infection can directly take place or secondary, sees with Hemolytic streptococcus more.As inducements such as suffering from cold, drench with rain, be overtired, when whole body or respiratory tract local defense ability are reduced, be stored in upper respiratory tract or can breed rapidly and cause from the virus of outer intrusion or antibacterial.Its pathology is from nasal cavity and the hyperemia of throat mucosa, edema, and epithelial cell destroys, and a small amount of monocyte infiltration has serosity and mucus to ooze out.But the primary disease secondary becomes acute bronchitis and causes cough; The Hemolytic streptococcus A group that causes respiratory tract infection is " nephritogenic strains ", and therefore, Hemolytic streptococcus causes organism immune response to cause Urinary system inflammation.Primary disease can annually take place, and can repeatedly take place.
China tradition traditional Chinese medical science has also been put down in writing the Chinese medicinal formulae of many treatment affection due to external wind and heat to many treatises of affection due to external wind and heat, as Lonicerae and Forsythiae Powder, SANGJU YIN, bilingual loose etc.These prescriptions adopt according to concrete symptom, are Chinese medicine content important component parts.The modern Chinese medicine theory is also at the Chinese medical theory in the ancient times of fully summing up, excavating or utilizing, just introduced the prescription for the treatment of affection due to external wind and heat as " Chinese Internal Medicine " (Shanghai science tech publishing house) of Wang Yongyan chief editor, the treatment affection due to external wind and heat has been played directive function preferably.Some pharmaceutical factories and Chinese medicine research institution have also released the Chinese patent medicine of some treatment anemopyretic cold in recent years, as flu cough-relieving electuary, tablets for treating influenza and inflammation, silver-colored chrysanthemum common cold tablet, honeysuckle flower common cold electuary, the clever granule of flu detoxifcation, flu peace sheet etc.Injection has QINGKAILING, Andrographolide, Herba Houttuyniae, Radix Bupleuri injection etc.But these Chinese medicine effects differ, and the specific aim that has is not strong, and curative effect is as one wishes not to the utmost, only play auxiliary treatment effect, the selling at exorbitant prices that has.
Chinese patent also discloses the medicine and the production method thereof of some treatment anemopyretic cold, as 98109110 disclose with bloom successively, Herba Ecliptae and Herba Plantaginis be the prescription of raw material.95100560 to disclose with Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Fructus Aurantii, Caulis Bambusae In Taenia, Radix Bupleuri, Radix Puerariae, Radix Scutellariae, Gypsum Fibrosum, Herba Menthae, Herba Schizonepetae, Radix Codonopsis, Rhizoma pinelliae cordatae, Fructus Jujubae, Rhizoma Zingiberis Recens, Radix Glycyrrhizae 15 flavor medicines be the prescription of raw material.94110359 to disclose with Radix Scutellariae, Fructus Forsythiae, Herba Schizonepetae, Flos Chrysanthemi Indici, Radix Scrophulariae, Cornu Bubali, Radix Et Rhizoma Rhei (wine is processed), Spina Gleditsiae, Nidus Vespae be the prescription of raw material.The formula components that said medicine has is too complicated, needs tens kinds of Chinese medicines to make up, and what have has only prescription and do not have production method, and the curative effect that has is definite inadequately, and the sick spectrum of the adaptation that has is narrow, thereby promotes the use of and be subjected to certain limitation.
Three, summary of the invention
The purpose of this invention is to provide a kind of with strong points to the affection due to external wind and heat disease cause of disease, determined curative effect, reasonable recipe, moderate cost, flu, cough, pharyngolaryngitis, the urinary tract infection that affection due to external wind and heat is caused has the Chinese patent medicine of significant curative effect.
Another object of the present invention provides the preparation method of this control affection due to external wind and heat medicine.
The inventor is in secular medical practice, from Chinese medical theory, adopt the Guangxi natural resources of Chinese medicinal materials,, screened tens kinds of Chinese medicinal formulaes through research for many years, compare repeatedly, therefrom selected medicines and prescription carry out pharmacodynamics, pharmacology, and research experiment such as clinical, finally invented a kind of good effect, abundant, moderate, wide, the advanced Chinese patent medicine of production technology of the sick spectrum of adaptation in medicine source, its main component and percentage by weight are as follows;
Radix Mussaendae 12～40; Flos Ilicis Asprellae 10～35; Radix Helicteris 7～25; Flos Lonicerae and/or Flos Chrysanthemi Indici 6～45.Because Flos Lonicerae is close with the Flos Chrysanthemi Indici drug effect, above-mentioned prescription can only be got wherein a kind of, also can two kinds all gets.
Weight (part) scope for preparing formula optimization of the present invention is:
Radix Mussaendae 20～30; Flos Ilicis Asprellae 15～25; Radix Helicteris 13～20; Flos Lonicerae and/or Flos Chrysanthemi Indici 6～35.
In order to strengthen the relieving the exterior syndrome with drugs of pungent in flavor and cool in nature effect, also include Flos Chrysanthemi in the raw material of the present invention, and wherein the weight of each raw material (part) proportioning is:
Radix Mussaendae 20～30; Flos Ilicis Asprellae 15～25; Radix Helicteris 13～20; Flos Lonicerae and/or Flos Chrysanthemi Indici 6～35; Flos Chrysanthemi 5～12.
In order to strengthen the effect of dampness removing expelling summer-heat, also include Herba Centellae in the raw material of the present invention, and wherein the weight of each raw material (part) proportioning is:
Radix Mussaendae 20～30; Flos Ilicis Asprellae 15～28; Radix Helicteris 13～20; Flos Lonicerae and/or Flos Chrysanthemi Indici 6～35; Flos Chrysanthemi 5～12; Herba Centellae 5～11.
The best component of the present invention and in weight (part) proportioning of each raw material be:
Radix Mussaendae 20～30; Flos Ilicis Asprellae 15～28; Radix Helicteris 13～20; Flos Lonicerae 6～14; Flos Chrysanthemi Indici 13～21; Flos Chrysanthemi 5～12; Herba Centellae 5～11.
Above-mentioned each component is made medicine production method of the present invention is:
(1) after above-mentioned component medicine decocting in water is carried, concentrates the thick paste A of leach cooking liquid.
(2) A is chilled to room temperature, carries out ethanol precipitation, get the ethanol supernatant concentration and become thick paste, promptly get intermediate products B.
(3) intermediate products B is processed into each dosage form according to a conventional method.
Above-mentioned Chinese medicine can be from " finding its another name, latin name and the place of production, usage Chinese pharmacopoeia and other Chinese medicine handbook.In order to understand the mechanism of disease preventing and treating of the present invention, existing side to prescription separates and is described below:
Radix Mussaendae heat-clearing and toxic substances removing, relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, clearing away summer-heat and eliminating dampness, Flos Lonicerae heat-clearing and toxic substances removing, and the clear sharp head that holds concurrently, sore-throat relieving, with Radix Mussaendae be monarch drug altogether; Flos Chrysanthemi dispelling wind to relieve the exterior syndrome, liver heat removing and eyesight improving, Flos Chrysanthemi Indici heat-clearing and toxic substances removing power is strong, the Flos Ilicis Asprellae cough-relieving sore-throat relieving that can promote the production of body fluid, the cough-relieving of Radix Helicteris dispersing lung-QI and dissipating phlegm has antipyretic and antidote functions concurrently, and four medicines are ministerial drug altogether; Herba Centellae energy removing summer-heat pyretic toxicity, the dampness removing expelling summer-heat, the principal drug assistance eliminating damp-heat goes out from the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, is to be adjuvant drug.Full side 7 flavors gather altogether that heat-clearing and toxic substances removing, relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, eliminating damp-heat, sore-throat relieving promote the production of body fluid, the merit of preventing phlegm from forming and stopping coughing, play the curative effect for the treatment of both the exterior and interior.
The present invention's main feature compared with the prior art is:
1, invention preferred above-mentioned Chinese medicine under Chinese medical theory instructs, scientific compatibility, making cooperatively interact various medicines in addition, learn from other's strong points to offset one's weaknesses, synergism, all medicines share, and pathogenic factor in the exterior can be dispelled, and interior-heat can be separated, noxious dampness can be sharp, productive cough can be ended, and full side plays altogether that heat-clearing and toxic substances removing, dispelling wind to relieve the exterior syndrome, dampness removing reduce phlegm, the effect of smooth throat to stop cough, treating both the exterior and interior.
2, clinical verification, the present invention can suppress the rheuminess thing of pulmonary branches trachea, have antiphlogistic effects, and antibacterials such as viruses such as influenza and Hemolytic streptococcus are had inhibitory action.But the immunocompetence of while enhancing body.Therefore can prevent and treat anemopyretic cold, cough-relieving, sore-throat relieving, sunstroke prevention and anti-urinary system infection.So the sick spectrum width of we's treatment, with strong points, therapeutic effect is remarkable.
3, utilize the local Chinese herbal medicine resource in Guangxi, scientific composition, production technology is newly advanced, and is workable, and moderate product price is fit to suitability for industrialized production.
4, produce in according to prescription Effective Components of Chinese Herb quality and preparation requirement, adopt or water is carried, or alcohol extraction, or the production technology of precipitate with ethanol and corresponding sterilizing methods, thereby the active constituent content height of product, not perishable, long shelf-life.
For showing the therapeutic effect of medicine of the present invention, below be the clinical research overview of doing for the present invention by Guilin institute of traditional Chinese medicine etc.:
The present invention carries out clinical trial case totally 482 examples, inpatient's 198 examples wherein, and clinic case 284 examples, all cases are all selected by the case choice criteria, meet dialectical requirement.Clinical trial is by district's group random packet, carry out non-blind controlled trial, wherein 301 examples are organized in treatment, matched group 181 examples, the patient 3 days of catching a cold the course of treatment, acute pharyngolaryngitis patient 5 days, 6 weeks of urinary tract infection patient, according to the curative effect judgment criteria, therapeutic outcome shows that flu organizes 121 examples, and total effective rate and total obvious effective rate are respectively 97.5% and 97.4%; Acute pharyngolaryngitis group 90 examples, total effective rate and total obvious effective rate are respectively 100% and 95.6%; Urinary tract infection group 90 examples, total effective rate and total obvious effective rate are respectively 97.8% and 90%.And above-mentioned each disease is pressed the security inspection interpretation of result at the treatment viewing duration, does not all find untoward reaction and toxic and side effects, shows that this product is safe.
Instructions of taking:
Granule, every day 3 times, each 1 bag (being equivalent to crude drug amount 6.4 gram/bags); Syrup, every day 3 times, each 20ml (be equivalent to crude drug amount 6.4 restrain/20ml); Oral liquid, every day 3 times, each 10ml (be equivalent to crude drug amount 6.4 restrain/10ml); Tablet, every day 3 times, each 2 ~ 3 (being equivalent to crude drug amount 2 gram/sheets); Capsule, every day 3 times, each 2 ~ 3 (being equivalent to crude drug amount 2 gram/grains).
Above clinical data discloses:
1. bright medical syrup has that heat-clearing and toxic substances removing, relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, sore-throat relieving promote the production of body fluid, the effect of clearing away summer-heat and eliminating dampness, preventing phlegm from forming and stopping coughing, and flu, cough, pharyngolaryngitis, lower warmer wetness-heat type stranguria (urinary tract infection) that affection due to external wind and heat is caused have therapeutical effect;
2. invention medicine instant (granule) or syrup can suppress the rheuminess thing of pulmonary branches trachea, have antiphlogistic effects, the immunocompetence of enhancing body.Antibacterials such as viruses such as influenza and Hemolytic streptococcus there is inhibitory action.Therefore can prevent and treat anemopyretic cold, cough-relieving, sore-throat relieving, sunstroke prevention and anti-urinary system infection.So the sick spectrum width of we's treatment, with strong points, therapeutic effect is remarkable.
3. medicine instant of the present invention (granule) and syrup are in treatment flu, acute pharyngitis, each sick kind of urinary tract infection, two groups of curative effects relatively, p＞0.05, there was no significant difference points out this medical syrup treatment flu, acute pharyngitis, urinary tract infection curative effect similar to granule (electuary).
4. this clinical trial has better repeatability; The present invention simultaneously is safe and reliable, through clinical observation, does not all find obvious adverse reaction and toxic and side effects.
5. the result of product studies on acute toxicity of the present invention and long term toxicity research shows that by intending with using the daily dose and the course of treatment the present invention be safe.
Above-mentioned prescription can be used as flu, cough, the pharyngolaryngitis of hospitalize external wind heat syndrome, the prescription of urinary tract infection, also can be used for sunstroke prevention.Patients is fried in shallow oil soup and is taken, and is more suitable for modern medicine enterprise effective component extracting and makes granule, syrup, oral liquid, tablet etc.
Four, specific embodiment embodiment:
Embodiment one:
Take by weighing following Chinese medicine ingredients: (unit: g)
Radix Mussaendae 150, Flos Ilicis Asprellae 100, Flos Lonicerae 62, Radix Helicteris 84
Its technological process of production is:
1, get above-mentioned Chinese medicine decocting 3 times, each 90 minutes, decocting liquid filtered merging filtrate, and being concentrated to relative density is the 1.20 thick paste A in (60 ℃ of tests down).
2, A is chilled to room temperature, adds ethanol, make to contain alcohol amount and reach 65%, leave standstill and made precipitation in 25 hours, get supernatant and filter, filtrate recycling ethanol, and be concentrated into the clear paste that relative density is 1.30 (40 ℃ of tests down), promptly get intermediate products B.
3, get intermediate products B and appropriate amount of auxiliary materials mixing, it is dry to granulate, and the sterilization packing gets the finished particle agent.
Embodiment two:
Take by weighing following Chinese medicine ingredients: (unit: g)
Radix Mussaendae 250, Flos Ilicis Asprellae 190, Radix Helicteris 170, Flos Chrysanthemi Indici 160
Its technological process of production is:
1, get above-mentioned Chinese medicine decocting 1 time, each 80 minutes, decocting liquid filtered merging filtrate, and being concentrated to relative density is the 1.18 thick paste A in (20 ℃ of tests down).
2, A is chilled to room temperature, adds ethanol, makes to contain alcohol amount and reach 80%, leaves standstill and makes precipitation in 20 hours, and get supernatant and filter, filtrate recycling ethanol, and be concentrated into the clear paste that relative density is 1.30 (65 ℃ of tests down), promptly get intermediate products B.
3, get intermediate products B and appropriate amount of auxiliary materials mixing, it is dry to granulate, and the sterilization packing gets the finished particle agent.
Embodiment three:
Take by weighing following Chinese medicine ingredients: (unit: g)
Radix Mussaendae 125, Flos Ilicis Asprellae 110, Flos Lonicerae 42, Radix Helicteris 84, Flos Chrysanthemi 45, Herba Centellae 40, Flos Chrysanthemi Indici 88
Its technological process of production is:
1, above-mentioned Chinese medicine decocting is 1 time, and each 50 minutes, decocting liquid filtered merging filtrate, and being concentrated to relative density is the 1.18 thick paste A in (50 ℃ of tests down).
2, A is chilled to room temperature, adds ethanol, makes to contain alcohol amount and reach 51%, leaves standstill and makes precipitation in 25 hours, and get supernatant and filter, filtrate recycling ethanol, and be concentrated into the clear paste that relative density is 1.25 (85 ℃ of tests down), promptly get intermediate products B.
3, get intermediate products B and appropriate amount of auxiliary materials mixing, it is dry to granulate, and the sterilization packing gets the finished particle agent.
Embodiment four:
Take by weighing following Chinese medicine ingredients: (unit: g)
Radix Mussaendae 125, Flos Ilicis Asprellae 110, Flos Lonicerae 42, Radix Helicteris 84, Flos Chrysanthemi 45, Herba Centellae 40, Flos Chrysanthemi Indici 88
Its technological process of production is:
1, above-mentioned Chinese medicine decocting is 1 time, and each 50 minutes, decocting liquid filtered merging filtrate, and being concentrated to relative density is the 1.05 thick paste A in (50 ℃ of tests down).
2, A is chilled to room temperature, adds ethanol, make to contain alcohol amount and reach 51%, leave standstill and made precipitation in 25 hours, get supernatant and filter, filtrate recycling ethanol, and be concentrated into the clear paste that relative density is 1.25 (85 ℃ of tests down), promptly get intermediate products B.
3, get intermediate products B and appropriate amount of auxiliary materials mixing, it is dry to granulate, and the sterilization packing gets the finished particle agent.
Embodiment five:
Take by weighing following Chinese medicine ingredients: (unit: g)
Radix Mussaendae 125, Flos Ilicis Asprellae 110, Flos Lonicerae 42, Radix Helicteris 84, Flos Chrysanthemi 45, Herba Centellae 40, Flos Chrysanthemi Indici 88
Its technological process of production is:
1, above-mentioned Chinese medicine decocting is 1 time, and each 50 minutes, decocting liquid filtered merging filtrate, and being concentrated to relative density is the 1.30 thick paste A in (50 ℃ of tests down).
2, A is chilled to room temperature, adds ethanol, make to contain alcohol amount and reach 51%, leave standstill and made precipitation in 25 hours, get supernatant and filter, filtrate recycling ethanol, and be concentrated into the clear paste that relative density is 1.25 (80 ℃ of tests down), promptly get intermediate products B.
3, get intermediate products B and appropriate amount of auxiliary materials mixing, it is dry to granulate, and the sterilization packing gets the finished particle agent.
Embodiment six:
Take by weighing following Chinese medicine ingredients: (unit: g)
Radix Mussaendae 130, Flos Ilicis Asprellae 100, Flos Lonicerae 30, Radix Helicteris 95, Flos Chrysanthemi 35, Herba Centellae 50, Flos Chrysanthemi Indici 75
Its technological process of production is:
1, gets above-mentioned Chinese medicine and get Radix Mussaendae 130g, Flos Ilicis Asprellae 105g, Flos Lonicerae 40g, Radix Helicteris 85g, Flos Chrysanthemi 44g, Herba Centellae 46g, Flos Chrysanthemi Indici 85g decocting 3 times, each 65 minutes, decocting liquid filters merging filtrate, is concentrated to the thick paste A of relative density 1.25 (49 ℃ of tests down).
2, A is chilled to room temperature, adds ethanol, make to contain alcohol amount and reach 48%, leave standstill and made precipitation in 26 hours, get supernatant and filter, filtrate recycling ethanol, and be concentrated into the clear paste that relative density is 1.26 (80 ℃ of tests down), promptly get intermediate products B.
3, get intermediate products B and an amount of sucrose and water, boil, add appropriate amount of auxiliary materials, and add water to 1000ml, stir, sterilization filling promptly gets syrup.
Embodiment seven:
Take by weighing following Chinese medicine ingredients: (unit: g)
Radix Mussaendae 143, Flos Ilicis Asprellae 110, Flos Lonicerae 35, Radix Helicteris 70, Flos Chrysanthemi 50, Herba Centellae 55, Flos Chrysanthemi Indici 90
Its technological process of production is:
1, get above-mentioned Chinese medicine decocting 3 times, each 70 minutes, decocting liquid filtered merging filtrate, was concentrated to the thick paste A of relative density (1.20 under 46 ℃).
2, A is chilled to room temperature, adds ethanol, make to contain alcohol amount and reach 54%, leave standstill and made precipitation in 23 hours, get supernatant and filter, filtrate recycling ethanol, and be concentrated into the clear paste that relative density is 1.13 (85 ℃ of tests down), promptly get intermediate products B.
3, get intermediate products B and an amount of syrup or Mel mixing, sterilization filling promptly gets oral liquid.
Embodiment eight:
Take by weighing following Chinese medicine ingredients: (unit: g)
Radix Mussaendae 110, Flos Ilicis Asprellae 100, Flos Lonicerae 50, Radix Helicteris 90, Flos Chrysanthemi 60, Herba Centellae 35, Flos Chrysanthemi Indici 70
Its technological process of production is:
1, get above-mentioned Chinese medicine decocting 2 times, each 50 minutes, decocting liquid filtered merging filtrate, was concentrated to the thick paste A of relative density 1.16 (51 ℃ of tests down).
2, A is chilled to room temperature, adds ethanol, make to contain alcohol amount and reach 52%, leave standstill and made precipitation in 26 hours, get supernatant and filter, filtrate recycling ethanol, and be concentrated into the clear paste that relative density is 1.24 (86 ℃ of tests down), promptly get intermediate products B.
3, get intermediate products B and appropriate amount of auxiliary materials mixing, granulate, sterilization, tabletting, tablet gets product.
Embodiment nine:
Take by weighing following Chinese medicine ingredients: (unit: g)
Radix Mussaendae 140, Flos Ilicis Asprellae 100, Flos Lonicerae 35, Radix Helicteris 95, Flos Chrysanthemi 35, Herba Centellae 60, Flos Chrysanthemi Indici 80
Its technological process of production is;
1, get above-mentioned Chinese medicine decocting 2 times, each 55 minutes, decocting liquid filtered merging filtrate, was concentrated to the thick paste A of relative density 1.19 (53 ℃ of tests down).
2, A is chilled to room temperature, adds ethanol, make to contain alcohol amount and reach 54%, leave standstill and made precipitation in 23 hours, get supernatant and filter, filtrate recycling ethanol, and be concentrated into the clear paste that relative density is 1.28 (85 ℃ of tests down), promptly get intermediate products B.
3, get intermediate products B and appropriate amount of auxiliary materials mixing, sterilization is granulated, and encapsulated, capsule gets product.
Claims (7)
1, a kind of medicine of preventing and treating affection due to external wind and heat is characterized in that it is to be made by following weight (part) proportion raw material: Radix Mussaendae 12～40; Flos Ilicis Asprellae 10～35; Radix Helicteris 7～25; Flos Lonicerae and/or Flos Chrysanthemi Indici 6～45.
2, a kind of medicine of preventing and treating affection due to external wind and heat according to claim 1 is characterized in that: wherein the weight of each raw material (part) proportioning is: Radix Mussaendae 20～30; Flos Ilicis Asprellae 15～25; Radix Helicteris 13～20; Flos Lonicerae and/or Flos Chrysanthemi Indici 6～35.
3, a kind of medicine of preventing and treating affection due to external wind and heat according to claim 2 is characterized in that: also include Flos Chrysanthemi in the raw material, and wherein the weight of each raw material (part) proportioning is a Radix Mussaendae 20～30; Flos Ilicis Asprellae 15～28; Radix Helicteris 13～20; Flos Lonicerae and/or Flos Chrysanthemi Indici 6～35; Flos Chrysanthemi 5～12.
4, a kind of medicine of preventing and treating affection due to external wind and heat according to claim 3 is characterized in that: also include Herba Centellae in the raw material, and wherein the weight of each raw material (part) proportioning is a Radix Mussaendae 20～30; Flos Ilicis Asprellae 15～28; Radix Helicteris 13～20; Flos Lonicerae and/or Flos Chrysanthemi Indici 6～35; Flos Chrysanthemi 5～12; Herba Centellae 5～11.
5, a kind of medicine of preventing and treating affection due to external wind and heat according to claim 4 is characterized in that: wherein the weight of each raw material (part) proportioning is: Radix Mussaendae 20～30; Flos Ilicis Asprellae 15～28; Radix Helicteris 13～20; Flos Lonicerae 6～14; Flos Chrysanthemi Indici 13～21 Flos Chrysanthemis 5～12; Herba Centellae 5～11.
6, according to the medicine of any one described control affection due to external wind and heat in the claim 1～5, it is characterized in that: said dosage form is a said dosage form on any pharmaceutics.
7, the preparation method of the medicine of the described control affection due to external wind and heat of claim 6 is characterized in that:
(1) get decocting in water such as Radix Mussaendae, Flos Ilicis Asprellae, Flos Lonicerae, Radix Helicteris, Flos Chrysanthemi, Herba Centellae, Flos Chrysanthemi Indici and carry after, concentrated leach cooking liquid gets thick paste A.
(2) A is chilled to room temperature, carries out ethanol precipitation, get the ethanol supernatant concentration and become thick paste, be i.e. intermediate products B.
Intermediate products B is processed into each dosage form according to a conventional method.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB01129082XA CN1151823C (en) | 2001-11-15 | 2001-11-15 | Medicine for preventing and treating cold and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB01129082XA CN1151823C (en) | 2001-11-15 | 2001-11-15 | Medicine for preventing and treating cold and its preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1350868A true CN1350868A (en) | 2002-05-29 |
| CN1151823C CN1151823C (en) | 2004-06-02 |
Family
ID=4668881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB01129082XA Expired - Lifetime CN1151823C (en) | 2001-11-15 | 2001-11-15 | Medicine for preventing and treating cold and its preparing process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1151823C (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100391500C (en) * | 2005-05-16 | 2008-06-04 | 广西纯正堂制药厂 | Chinese medicine preparation for treating wind-heat syndrome of acute pharyngitis and its preparation process |
| CN100571527C (en) * | 2006-08-21 | 2009-12-23 | 李浪辉 | A kind of cold tea |
| CN102949681A (en) * | 2011-08-22 | 2013-03-06 | 富力 | Composition for preventing or treating colds, and its preparation method |
| CN103316313A (en) * | 2013-05-20 | 2013-09-25 | 缪长法 | Traditional Chinese medicine used for treating bronchitis, and preparation method thereof |
| CN103340262A (en) * | 2013-06-22 | 2013-10-09 | 梁春林 | Ginseng fruit health-care tea |
| CN104547293A (en) * | 2014-12-25 | 2015-04-29 | 姜新帅 | Traditional Chinese medicine composition for treating influenza |
| CN112641855A (en) * | 2020-12-24 | 2021-04-13 | 广东康明医院管理有限公司 | A Chinese medicinal composition for treating or preventing common cold, and its preparation method |
-
2001
- 2001-11-15 CN CNB01129082XA patent/CN1151823C/en not_active Expired - Lifetime
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100391500C (en) * | 2005-05-16 | 2008-06-04 | 广西纯正堂制药厂 | Chinese medicine preparation for treating wind-heat syndrome of acute pharyngitis and its preparation process |
| CN100571527C (en) * | 2006-08-21 | 2009-12-23 | 李浪辉 | A kind of cold tea |
| CN102949681A (en) * | 2011-08-22 | 2013-03-06 | 富力 | Composition for preventing or treating colds, and its preparation method |
| CN102949681B (en) * | 2011-08-22 | 2014-11-12 | 富力 | Composition for preventing or treating colds, and its preparation method |
| CN103316313A (en) * | 2013-05-20 | 2013-09-25 | 缪长法 | Traditional Chinese medicine used for treating bronchitis, and preparation method thereof |
| CN103340262A (en) * | 2013-06-22 | 2013-10-09 | 梁春林 | Ginseng fruit health-care tea |
| CN104547293A (en) * | 2014-12-25 | 2015-04-29 | 姜新帅 | Traditional Chinese medicine composition for treating influenza |
| CN112641855A (en) * | 2020-12-24 | 2021-04-13 | 广东康明医院管理有限公司 | A Chinese medicinal composition for treating or preventing common cold, and its preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1151823C (en) | 2004-06-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1899535A (en) | Method for preparing dermopathic blood toxic capsule | |
| CN1724040A (en) | Chinese patent drug for treating infantile cold and repeated cold, and its prepn. method | |
| CN1210047C (en) | Medicine for treating cold and preparation method thereof | |
| CN1127648A (en) | Chinese medicine composition with antipyretic and antidote functions and use thereof | |
| CN102805776B (en) | Traditional Chinese medicine composition and preparation method of traditional Chinese medicine composition | |
| CN1151823C (en) | Medicine for preventing and treating cold and its preparing process | |
| CN1298362C (en) | Compound Chinese medicine prepn for treating pulvic infection and its prepn process | |
| CN103599343B (en) | A kind of pharmaceutical composition for the treatment of diabetes and its production and use | |
| CN103054952A (en) | Medicine for treating periodontitis and preparation method thereof | |
| CN103006893A (en) | Medicine for treating chronic rhinitis and preparation method thereof | |
| CN1899499A (en) | Chinese medicine composition for treating cold and its preparing method and use | |
| CN103040949A (en) | Drug for treating cold and preparation method thereof | |
| CN102210776A (en) | Medicament for treating common cold, and preparation method thereof | |
| CN1261130C (en) | Medicine for dispelling tinea | |
| CN1314434C (en) | Heat-clearing and detoxic medicine and its preparation method | |
| CN1579513A (en) | Compound throat sucking-tablet of semen sterculiae scaphigerae and oral tonic thereof | |
| CN102670809A (en) | Drug for curing pharyngitis and preparing method thereof | |
| CN102743658A (en) | Traditional Chinese medicinal composition for treating urticaria | |
| CN1245204C (en) | Medicine for curing acute pharyngitis and its preparing method | |
| CN1151830C (en) | Compound Chinese medicine tea bag for curing acute and chronic urethritis, and its preparing method | |
| CN1217694C (en) | A reducing fever anti-cold medicine combination and the preparation process thereof | |
| CN1160563A (en) | Chinese patent drug for curing headache | |
| CN1768788A (en) | Formulation for treating gastrointestinal disease and production method thereof | |
| CN104721670A (en) | TCM (traditional Chinese medicine) composition for treating Laryngopharyngitis and preparing method thereof | |
| CN104116029A (en) | Health food for enhancing immunity and preparation method of health food |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20040602 |
|
| CX01 | Expiry of patent term |