CN1899535A - Method for preparing dermopathic blood toxic capsule - Google Patents
Method for preparing dermopathic blood toxic capsule Download PDFInfo
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- CN1899535A CN1899535A CNA2006100363301A CN200610036330A CN1899535A CN 1899535 A CN1899535 A CN 1899535A CN A2006100363301 A CNA2006100363301 A CN A2006100363301A CN 200610036330 A CN200610036330 A CN 200610036330A CN 1899535 A CN1899535 A CN 1899535A
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Abstract
The dermopathic blood poison treating capsule for treating dermopathy is prepared with madder and other 38 kinds of Chinese medicinal materials, and through washing, drying, crushing, grinding into fine powder, mixing with proper amount of talc powder and encapsulating. It can cleare away blood heat and toxic matter, eliminating swelling and stopping itching. Grinding the materials into fine powder of size below 47 micron can speed the absorption of skin on the effective medicine components and raise the healing effect greatly.
Description
Technical field
The present invention relates to a kind of endo-medicine for the treatment of dermatosis, particularly relate to a kind of being used for the treatment of because of meridians discord, the dry preparation method that causes the dermopathic blood toxic capsule of dermatosis of damp and hot blood.
Background technology
Human body causes dermatosis such as rubella, eczema, scratchy, freckle as well as acne, face thorn brandy nose, sore swollen toxin, beriberi scabies easily because of meridians discord, damp and hot blood are dry." the dermopathic blood poison pill " of Xiao Shouing is though also have the effect of blood-cleaning detoxifying, repellent antipruritic on the market, but because the preparation method of this product is to continue to use the production technology of traditional water pill dosage form, whole pulverizing medicinal materials in only will filling a prescription are to the 80-100 order, water is adhesion-molded, therefore this product exists obviously not enough: (1) is unfavorable for that the active ingredient in the medical material oozes out from plant cell, active ingredient in the medical material is absorbed not exclusively, cause waste; (2) dosage that need take is big, is unfavorable for that the people swallows; (3) the product onset is slow, can not bring into play curative effect the fastest, the biglyyest; (4) the easy moisture absorption of water pill dosage form causes that product is mouldy, preserves and carry all inconvenient.
Summary of the invention
At above problem, the invention provides a kind of preparation method of dermopathic blood toxic capsule, promptly adopt superfine communication technique, prepare novel dermopathic blood toxic capsule.Concrete technical scheme is as follows:
A kind of preparation method of dermopathic blood toxic capsule is equipped with raw material by following proportioning earlier: Radix Rubiae 30g, Semen Persicae 30g, Herba Schizonepetae 30g, Periostracum Serpentis 15g, Radix Paeoniae Rubra 30g, Radix Angelicae Sinensis 30g, Rhizoma Imperatae 60g, Fructus Kochiae 30g, Fructus Xanthii 30g, Radix Rehmanniae 30g, Fructus Forsythiae 30g, Flos Lonicerae 30g, Herba Corydalis Bungeanae 30g, Rhizoma Smilacis Glabrae 30g, Cortex Phellodendri 15g, Spina Gleditsiae 30g, Radix Platycodonis 30g, Herba Leonuri 30g, Semen Armeniacae Amarum 30g, Radix Saposhnikoviae 15g, red volt Siberian cocklebur 60g, Radix Paeoniae Alba 30g, Periostracum Cicadae 15g, Fructus Arctii 30g, Cortex Moutan 30g, Cortex Dictamni 30g, Radix Rehmanniae Preparata 30g, Radix Et Rhizoma Rhei 30g, Caulis Lonicerae 30g, Radix Arnebiae (Radix Lithospermi) 15g, Rhizoma Bolbostematis 30g, Rhizoma Chuanxiong 15g, Radix Glycyrrhizae 30g, Radix Angelicae Dahuricae 15g, Radix Semiaquilegiae 30g, Cortex cercis chinensis 15g, Caulis Spatholobi 30g, Herba Spirodelae 15g, Flos Carthami 15g; Be prepared according to the following steps then:
1) above-mentioned raw materials is cleaned up;
2) clean raw material is carried out drying;
3) dried raw material is ground into coarse powder, crosses the 80-100 mesh sieve;
4) above-mentioned coarse powder is carried out micronizing again, cross 300 mesh sieves, get micropowders;
5) add an amount of Pulvis Talci in above-mentioned micropowders, mix homogeneously is inserted in the capsule then, can obtain required finished product.
In the above-mentioned preparation method, the temperature of raw material drying is 60-100 ℃, and the exsiccant time is 4-6 hour.
In the above-mentioned preparation method, adding talcous amount is 1% of micropowders total amount.
In the above-mentioned preparation method, the capsule that product is selected for use is a medicinal hard capsule, and model is No. 0 or No. 00.
In the above-mentioned preparation method, the micronizing of raw material is to carry out being lower than under 10 ℃ the temperature, to avoid the destruction of the high temperature gelatinizing of medical material in crushing process to active ingredient.
In the above-mentioned preparation method, the micronizing of raw material realizes by jet mill, vibromill, ball mill or planetary mills.
The said flow pulverizer comprises horizontal circle disc type jet mill, circulation tubular type jet mill, to spray formula inverted draft pulverizer, crash panel target formula jet mill or fluidized bed type jet mill.
Product-dermopathic blood toxic capsule of the present invention is formed its function blood-cleaning detoxifying, repellent antipruritic by 39 flavor Chinese medicines such as Radix Rubiae, Radix Paeoniae Rubra, the Fructus Kochiae, Cortex Moutan, Radix Et Rhizoma Rhei (wine stir-fry), Rhizoma Smilacis Glabrae, Flos Lonicerae, red volt Siberian cocklebur, Cortex Dictamni, Rhizoma Imperatae, Herba Corydalis Bungeanae, Spina Gleditsiae.The clinical dermatosis such as meridians discord, the dry rubella that causes of damp and hot blood, eczema, scratchy, freckle as well as acne, face thorn brandy nose, sore swollen toxin, beriberi scabies that are used for the treatment of, determined curative effect is a kind of outstanding dermatosis oral medicine.
It is broken that the present invention carries out micropowder to 39 flavor medical materials, and promptly the cell grade micropowder is broken, and diameter of particle reaches (fully by 300 mesh sieves) below 47 microns.The cell grade micropowder is broken to be to break the disintegrating process technology that the Chinese crude drug cell is a purpose, cell wall in the crushing process (film) is broken, to more help alleviating it active ingredient will be discharged formed resistance, and cellular content is directly exposed and improve its dissolution, thereby make human body tangible breakthrough arranged to the assimilation ratio and the speed of effective ingredient, thereby the single that makes the patient takes quantity and significantly reduces, and also improved the treating for skin disease effect.In addition, product of the present invention is made capsule, more helps preserving and carrying.
The specific embodiment
Embodiment 1
Get Radix Rubiae 30g, Semen Persicae 30g, Herba Schizonepetae 30g, Periostracum Serpentis 15g, Radix Paeoniae Rubra 30g, Radix Angelicae Sinensis 30g, Rhizoma Imperatae 60g, Fructus Kochiae 30g, Fructus Xanthii 30g, Radix Rehmanniae 30g, Fructus Forsythiae 30g, Flos Lonicerae 30g, Herba Corydalis Bungeanae 30g, Rhizoma Smilacis Glabrae 30g, Cortex Phellodendri 15g, Spina Gleditsiae 30g, Radix Platycodonis 30g, Herba Leonuri 30g, Semen Armeniacae Amarum 30g, Radix Saposhnikoviae 15g, red volt Siberian cocklebur 60g, Radix Paeoniae Alba 30g, Periostracum Cicadae 15g, Fructus Arctii 30g, Cortex Moutan 30g, Cortex Dictamni 30g, Radix Rehmanniae Preparata 30g, Radix Et Rhizoma Rhei 30g, Caulis Lonicerae 30g, Radix Arnebiae (Radix Lithospermi) 15g, Rhizoma Bolbostematis 30g, Rhizoma Chuanxiong 15g, Radix Glycyrrhizae 30g, Radix Angelicae Dahuricae 15g, Radix Semiaquilegiae 30g, Cortex cercis chinensis 15g, Caulis Spatholobi 30g, Herba Spirodelae 15g, Flos Carthami 15g; Be prepared according to the following steps then:
1) above-mentioned raw materials is cleaned up;
2) clean raw material is carried out drying, exsiccant temperature is 60 ℃, and the time is 6 hours;
3) dried raw material is ground into coarse powder, crosses 80 mesh sieves;
4) above-mentioned coarse powder is carried out micronizing again, cross 300 mesh sieves, get micropowders;
5) add Pulvis Talci in above-mentioned micropowders, talcous amount is 1% of a micropowders total amount, and mix homogeneously is then inserted in No. 0 capsule, can obtain required dermopathic blood toxic capsule.
Be equipped with raw material in above ratio during batch process.
Embodiment 2
Get Radix Rubiae 30g, Semen Persicae 30g, Herba Schizonepetae 30g, Periostracum Serpentis 15g, Radix Paeoniae Rubra 30g, Radix Angelicae Sinensis 30g, Rhizoma Imperatae 60g, Fructus Kochiae 30g, Fructus Xanthii 30g, Radix Rehmanniae 30g, Fructus Forsythiae 30g, Flos Lonicerae 30g, Herba Corydalis Bungeanae 30g, Rhizoma Smilacis Glabrae 30g, Cortex Phellodendri 15g, Spina Gleditsiae 30g, Radix Platycodonis 30g, Herba Leonuri 30g, Semen Armeniacae Amarum 30g, Radix Saposhnikoviae 15g, red volt Siberian cocklebur 60g, Radix Paeoniae Alba 30g, Periostracum Cicadae 15g, Fructus Arctii 30g, Cortex Moutan 30g, Cortex Dictamni 30g, Radix Rehmanniae Preparata 30g, Radix Et Rhizoma Rhei 30g, Caulis Lonicerae 30g, Radix Arnebiae (Radix Lithospermi) 15g, Rhizoma Bolbostematis 30g, Rhizoma Chuanxiong 15g, Radix Glycyrrhizae 30g, Radix Angelicae Dahuricae 15g, Radix Semiaquilegiae 30g, Cortex cercis chinensis 15g, Caulis Spatholobi 30g, Herba Spirodelae 15g, Flos Carthami 15g; Be prepared according to the following steps then:
1) above-mentioned raw materials is cleaned up;
2) clean raw material is carried out drying, exsiccant temperature is 80 ℃, and the time is 5 hours;
3) dried raw material is ground into coarse powder, crosses 100 mesh sieves;
4) above-mentioned coarse powder is carried out micronizing again, cross 300 mesh sieves, get micropowders;
5) add Pulvis Talci in above-mentioned micropowders, talcous amount is 1% of a micropowders total amount, and mix homogeneously is then inserted in No. 00 capsule, can obtain required dermopathic blood toxic capsule.
Be equipped with raw material in above ratio during batch process.
Embodiment 3
Get Radix Rubiae 30g, Semen Persicae 30g, Herba Schizonepetae 30g, Periostracum Serpentis 15g, Radix Paeoniae Rubra 30g, Radix Angelicae Sinensis 30g, Rhizoma Imperatae 60g, Fructus Kochiae 30g, Fructus Xanthii 30g, Radix Rehmanniae 30g, Fructus Forsythiae 30g, Flos Lonicerae 30g, Herba Corydalis Bungeanae 30g, Rhizoma Smilacis Glabrae 30g, Cortex Phellodendri 15g, Spina Gleditsiae 30g, Radix Platycodonis 30g, Herba Leonuri 30g, Semen Armeniacae Amarum 30g, Radix Saposhnikoviae 15g, red volt Siberian cocklebur 60g, Radix Paeoniae Alba 30g, Periostracum Cicadae 15g, Fructus Arctii 30g, Cortex Moutan 30g, Cortex Dictamni 30g, Radix Rehmanniae Preparata 30g, Radix Et Rhizoma Rhei 30g, Caulis Lonicerae 30g, Radix Arnebiae (Radix Lithospermi) 15g, Rhizoma Bolbostematis 30g, Rhizoma Chuanxiong 15g, Radix Glycyrrhizae 30g, Radix Angelicae Dahuricae 15g, Radix Semiaquilegiae 30g, Cortex cercis chinensis 15g, Caulis Spatholobi 30g, Herba Spirodelae 15g, Flos Carthami 15g; Be prepared according to the following steps then:
1) above-mentioned raw materials is cleaned up;
2) clean raw material is carried out drying, exsiccant temperature is 100 ℃, and the time is 4 hours;
3) dried raw material is ground into coarse powder, crosses 80 mesh sieves;
4) above-mentioned coarse powder is carried out micronizing again, cross 300 mesh sieves, get micropowders;
5) add Pulvis Talci in above-mentioned micropowders, talcous amount is 1% of a micropowders total amount, and mix homogeneously is then inserted in No. 00 capsule, can obtain required dermopathic blood toxic capsule.
Be equipped with raw material in above ratio during batch process.
Among the above embodiment, can utilize jet mill, vibromill, ball mill or planetary mills to realize to the micronizing of raw material, wherein jet mill can be horizontal circle disc type jet mill, circulation tubular type jet mill, to spray formula inverted draft pulverizer, crash panel target formula jet mill, fluidized bed type jet mill.The broken operation of micropowder is generally carried out being lower than under 10 ℃.
The dermopathic blood toxic capsule that the present invention is prepared, through medical institutions' clinical verifications such as Guangzhou Affiliated Hospital of Zhongshan Medical Univ., Guangzhou No.2 People's Hospital, product has the effect of blood-cleaning detoxifying, repellent antipruritic, treatment is stung dermatosis such as brandy nose, sore swollen toxin, beriberi scabies, determined curative effect because of meridians discord, the dry rubella that causes of damp and hot blood, eczema, scratchy, freckle as well as acne, face.
Claims (7)
1. the preparation method of a dermopathic blood toxic capsule is characterized in that: be equipped with raw material by following proportioning earlier: Radix Rubiae 30g, Semen Persicae 30g, Herba Schizonepetae 30g, Periostracum Serpentis 15g, Radix Paeoniae Rubra 30g, Radix Angelicae Sinensis 30g, Rhizoma Imperatae 60g, Fructus Kochiae 30g, Fructus Xanthii 30g, Radix Rehmanniae 30g, Fructus Forsythiae 30g, Flos Lonicerae 30g, Herba Corydalis Bungeanae 30g, Rhizoma Smilacis Glabrae 30g, Cortex Phellodendri 15g, Spina Gleditsiae 30g, Radix Platycodonis 30g, Herba Leonuri 30g, Semen Armeniacae Amarum 30g, Radix Saposhnikoviae 15g, red volt Siberian cocklebur 60g, Radix Paeoniae Alba 30g, Periostracum Cicadae 15g, Fructus Arctii 30g, Cortex Moutan 30g, Cortex Dictamni 30g, Radix Rehmanniae Preparata 30g, Radix Et Rhizoma Rhei 30g, Caulis Lonicerae 30g, Radix Arnebiae (Radix Lithospermi) 15g, Rhizoma Bolbostematis 30g, Rhizoma Chuanxiong 15g, Radix Glycyrrhizae 30g, Radix Angelicae Dahuricae 15g, Radix Semiaquilegiae 30g, Cortex cercis chinensis 15g, Caulis Spatholobi 30g, Herba Spirodelae 15g, Flos Carthami 15g; Be prepared according to the following steps then:
1) above-mentioned raw materials is cleaned up;
2) clean raw material is carried out drying;
3) dried raw material is ground into coarse powder, crosses the 80-100 mesh sieve;
4) above-mentioned coarse powder is carried out micronizing again, cross 300 mesh sieves, get micropowders;
5) add an amount of Pulvis Talci in above-mentioned micropowders, mix homogeneously is inserted in the capsule then, can obtain required finished product.
2. the preparation method of dermopathic blood toxic capsule according to claim 1, it is characterized in that: the temperature of raw material drying is 60-100 ℃, the exsiccant time is 4-6 hour.
3. the preparation method of dermopathic blood toxic capsule according to claim 1, it is characterized in that: adding talcous amount is 1% of micropowders total amount.
4. the preparation method of dermopathic blood toxic capsule according to claim 1, it is characterized in that: the capsule that product is selected for use is a medicinal hard capsule, model is No. 0 or No. 00.
5, according to the preparation method of each described dermopathic blood toxic capsule of claim 1-4, it is characterized in that: the micronizing of raw material is to carry out being lower than under 10 ℃ the temperature.
6, according to the preparation method of each described dermopathic blood toxic capsule of claim 1-4, it is characterized in that: the micronizing of raw material realizes by jet mill, vibromill, ball mill or planetary mills.
7, the preparation method of dermopathic blood toxic capsule according to claim 6 is characterized in that: described jet mill comprises horizontal circle disc type jet mill, circulation tubular type jet mill, to spray formula inverted draft pulverizer, crash panel target formula jet mill, fluidized bed type jet mill.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006100363301A CN1899535A (en) | 2006-06-28 | 2006-06-28 | Method for preparing dermopathic blood toxic capsule |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2006100363301A CN1899535A (en) | 2006-06-28 | 2006-06-28 | Method for preparing dermopathic blood toxic capsule |
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| CN1899535A true CN1899535A (en) | 2007-01-24 |
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102068639A (en) * | 2011-01-10 | 2011-05-25 | 王宝香 | Externally traditional Chinese medicine for treating pustulosis |
| CN101642546B (en) * | 2009-06-14 | 2011-05-25 | 李承平 | Chinese patent medicine for eliminating toxin and beautifying faces |
| CN101596270B (en) * | 2009-07-01 | 2011-06-29 | 李春荣 | Medicine for treating chronic pharyngitis and preparation method thereof |
| CN102178874A (en) * | 2010-12-14 | 2011-09-14 | 史志辉 | Preparation method of Chinese medicinal tablet for treating skin diseases |
| CN102274322A (en) * | 2011-08-04 | 2011-12-14 | 长春市南关区中医院 | Chinese medicinal preparation for treating eczema |
| CN102379968A (en) * | 2011-10-18 | 2012-03-21 | 孙克勤 | Traditional Chinese medicine composition for treating purpura |
| CN102973836A (en) * | 2012-12-28 | 2013-03-20 | 李鑫 | Traditional Chinese medicine formula for curing pediatric chronic urticaria |
| CN103356777A (en) * | 2013-07-17 | 2013-10-23 | 张桂凤 | Medicament for treating rosacea |
| CN103550680A (en) * | 2013-10-22 | 2014-02-05 | 张礼周 | Traditional Chinese medicine prescription for treating hyperbilirubinemia caused skin itch and preparation method thereof |
| CN104547718A (en) * | 2015-01-30 | 2015-04-29 | 张希梅 | Pharmaceutical composition for preventing and treating children fracture internal fixation postoperative infection |
| CN104667070A (en) * | 2015-02-12 | 2015-06-03 | 广东国医堂制药股份有限公司 | Medicine for treating skin diseases and preparation method of medicine |
| CN105232684A (en) * | 2015-11-18 | 2016-01-13 | 包莉丽 | Medicine for treating chronic eczema |
| CN108514551A (en) * | 2018-05-18 | 2018-09-11 | 北京同仁堂制药有限公司 | A kind of preparation method of medicine pill |
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- 2006-06-28 CN CNA2006100363301A patent/CN1899535A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101642546B (en) * | 2009-06-14 | 2011-05-25 | 李承平 | Chinese patent medicine for eliminating toxin and beautifying faces |
| CN101596270B (en) * | 2009-07-01 | 2011-06-29 | 李春荣 | Medicine for treating chronic pharyngitis and preparation method thereof |
| CN102178874B (en) * | 2010-12-14 | 2012-02-29 | 史志辉 | Preparation method of Chinese medicinal tablet for treating skin diseases |
| CN102178874A (en) * | 2010-12-14 | 2011-09-14 | 史志辉 | Preparation method of Chinese medicinal tablet for treating skin diseases |
| CN102068639A (en) * | 2011-01-10 | 2011-05-25 | 王宝香 | Externally traditional Chinese medicine for treating pustulosis |
| CN102274322B (en) * | 2011-08-04 | 2013-03-27 | 长春市南关区中医院 | Chinese medicinal preparation for treating eczema |
| CN102274322A (en) * | 2011-08-04 | 2011-12-14 | 长春市南关区中医院 | Chinese medicinal preparation for treating eczema |
| CN102379968B (en) * | 2011-10-18 | 2013-09-11 | 孙克勤 | Traditional Chinese medicine composition for treating purpura |
| CN102379968A (en) * | 2011-10-18 | 2012-03-21 | 孙克勤 | Traditional Chinese medicine composition for treating purpura |
| CN102973836B (en) * | 2012-12-28 | 2014-10-08 | 潍坊市市直机关医院 | Traditional Chinese medicine formula for curing pediatric chronic urticaria |
| CN102973836A (en) * | 2012-12-28 | 2013-03-20 | 李鑫 | Traditional Chinese medicine formula for curing pediatric chronic urticaria |
| CN103356777A (en) * | 2013-07-17 | 2013-10-23 | 张桂凤 | Medicament for treating rosacea |
| CN103356777B (en) * | 2013-07-17 | 2015-02-18 | 张桂凤 | Medicament for treating rosacea |
| CN103550680A (en) * | 2013-10-22 | 2014-02-05 | 张礼周 | Traditional Chinese medicine prescription for treating hyperbilirubinemia caused skin itch and preparation method thereof |
| CN103550680B (en) * | 2013-10-22 | 2015-12-30 | 张礼周 | A kind ofly treat hyperbilirubinemia Chinese medicinal formulae causing skin pruritus and preparation method thereof |
| CN104547718A (en) * | 2015-01-30 | 2015-04-29 | 张希梅 | Pharmaceutical composition for preventing and treating children fracture internal fixation postoperative infection |
| CN104667070A (en) * | 2015-02-12 | 2015-06-03 | 广东国医堂制药股份有限公司 | Medicine for treating skin diseases and preparation method of medicine |
| CN105232684A (en) * | 2015-11-18 | 2016-01-13 | 包莉丽 | Medicine for treating chronic eczema |
| CN108514551A (en) * | 2018-05-18 | 2018-09-11 | 北京同仁堂制药有限公司 | A kind of preparation method of medicine pill |
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