CN103550680B

CN103550680B - A kind ofly treat hyperbilirubinemia Chinese medicinal formulae causing skin pruritus and preparation method thereof

Info

Publication number: CN103550680B
Application number: CN201310498064.4A
Authority: CN
Inventors: 张礼周
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-10-22
Filing date: 2013-10-22
Publication date: 2015-12-30
Anticipated expiration: 2033-10-22
Also published as: CN103550680A

Abstract

The invention discloses and a kind ofly treat hyperbilirubinemia Chinese medicinal formulae causing skin pruritus and preparation method thereof, it is made up of the raw material of following weight portion: Radix Saposhnikoviae 10-15, Herba Schizonepetae 15-20, Cortex Dictamni 12-16, Periostracum Cicadae 8-12, Radix Angelicae Sinensis 10-15, Herba Ephedrae 4-8, Zornia diphylla (Linn.) Pers. 7-11, Radix Paeoniae Rubra 3-5, Pericarpium Granati 6-12, Radix Glycyrrhizae 10-15, Radix Bupleuri 5-10, Herba Artemisiae Scopariae 8-12, Radix Curcumae 9-13, Flos Campsis 5-10, Rhizoma Polygoni Cuspidati 10-15, Radix Et Rhizoma Rhei 5-10, Rabdosia rubescens 14-18, Fructus Schisandrae Chinensis 10-15, Folium Lycii 11-17, Radix Sophorae Flavescentis 8-12, Herba Lysimachiae 5-10, propolis 10-15.The all medicines of the present invention share there is removing damp-heat, the effect such as dispelling wind for relieving itching, removing heat from blood are moisturized, antiviral, antiinflammatory, promoting the function of the gallbladder to alleviate jaundice, hepatoprotective, reduction cholate, antihistamine secretion, antiallergic, skin pruritus is caused for treatment hyperbilirubinemia there is significant curative effect, and curative effect is quick, short treating period, cure rate is high, not easily recur, have no side effect, have no adverse reaction.

Description

A kind ofly treat hyperbilirubinemia Chinese medicinal formulae causing skin pruritus and preparation method thereof

Technical field

The present invention relates to and a kind ofly treat hyperbilirubinemia Chinese medicinal formulae causing skin pruritus and preparation method thereof, belong to technical field of Chinese medicines.

Background technology

Chronic hepatopathy hyperbilirubinemia makes gallbladder salinity in serum, skin obviously increase, and excite nerve the wooden tip and cause general skin pruritus, and patient usually scratches skin, even causes local infection.In addition, pruritus makes patient sleeps obviously decline, and causes patient's immunity degradation and stress to increase, causes the state of an illness to increase the weight of further.Although the Chinese medicinal formulae that existing treatment hyperbilirubinemia causes skin pruritus is of a great variety, really there is therapeutic effect also few, and it is slow to there is curative effect, easily recurs, the shortcomings such as cure rate is low.

Summary of the invention

The object of the invention is to for the deficiencies in the prior art, a kind of evident in efficacy, the course for the treatment of is fast, cure rate is high treatment hyperbilirubinemia Chinese medicinal formulae causing skin pruritus and preparation method thereof is provided.

The technical solution used in the present invention is as follows:

Treat the Chinese medicinal formulae that hyperbilirubinemia causes skin pruritus, be made up of the raw material of following weight portion: Radix Saposhnikoviae 10-15, Herba Schizonepetae 15-20, Cortex Dictamni 12-16, Periostracum Cicadae 8-12, Radix Angelicae Sinensis 10-15, Herba Ephedrae 4-8, Zornia diphylla (Linn.) Pers. 7-11, Radix Paeoniae Rubra 3-5, Pericarpium Granati 6-12, Radix Glycyrrhizae 10-15, Radix Bupleuri 5-10, Herba Artemisiae Scopariae 8-12, Radix Curcumae 9-13, Flos Campsis 5-10, Rhizoma Polygoni Cuspidati 10-15, Radix Et Rhizoma Rhei 5-10, Rabdosia rubescens 14-18, Fructus Schisandrae Chinensis 10-15, Folium Lycii 11-17, Radix Sophorae Flavescentis 8-12, Herba Lysimachiae 5-10, propolis 10-15.

Preferably, treat the Chinese medicinal formulae that hyperbilirubinemia causes skin pruritus, be made up of the raw material of following weight portion: Radix Saposhnikoviae 15, Herba Schizonepetae 15, Cortex Dictamni 15, Periostracum Cicadae 10, Radix Angelicae Sinensis 10, Herba Ephedrae 6, Zornia diphylla (Linn.) Pers. 9, Radix Paeoniae Rubra 4, Pericarpium Granati 8, Radix Glycyrrhizae 10, Radix Bupleuri 10, Herba Artemisiae Scopariae 10, Radix Curcumae 10, Flos Campsis 7, Rhizoma Polygoni Cuspidati 10, Radix Et Rhizoma Rhei 6, Rabdosia rubescens 16, Fructus Schisandrae Chinensis 10, Folium Lycii 14, Radix Sophorae Flavescentis 10, Herba Lysimachiae 10, propolis 10.

Preparation process is as follows: take said medicine mix homogeneously by formula proportion, be ground into fine powder, becomes decoction, tablet, powder, pill, granule or capsule by conventional pharmaceutical processes.

Chinese medicine is thought: " itch from wind come " is antipruritic first dispels the wind, and Radix Saposhnikoviae, Herba Schizonepetae, Periostracum Cicadae, Pericarpium Granati, get its dispelling wind for relieving itching effect, Cortex Dictamni have dispel the wind, heat clearing and damp drying effect can use.Herba Ephedrae contains ephedrine, has paralysis nerve, antivirus action.The traditional Chinese medical science generally calls hepatopathy, liver cirrhosis " jaundice, tympanites ", mainly soothing the liver, jaundice eliminating in treatment, and Radix Bupleuri, Herba Artemisiae Scopariae, Radix Curcumae, Rhizoma Polygoni Cuspidati, Radix Et Rhizoma Rhei have soothing the liver, jaundice; Radix Glycyrrhizae contains glycyrrhizic glycoside and has parahormone effect, there is clear and definite anti-allergic effects, propolis contains unavailable polysaccharide, and energy and cholate combine and form complex, and cholesterol also can be hindered in the absorption of intestinal, Herba Lysimachiae also can reduce cholate, Radix Angelicae Sinensis have invigorate blood circulation, blood tonification effect, chronic hepatopathy causes general skin pruritus, because patient often scratches, pachyderma, coarse, Radix Angelicae Sinensis can play invigorate blood circulation, YIN nourishing accumulates dry effect.Radix Sophorae Flavescentis, Fructus Schisandrae Chinensis have antiviral, hepatoprotective, effect of reducing enzyme levels, and Radix Paeoniae Rubra, Flos Campsis have that clots absorbing dispels the wind, removing heat from blood detumescence effect; Rabdosia rubescens has heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, bacteriostasis; Folium Lycii has tonify deficiency benefit essence, relieves heat and thirst, dispelling pathogenic wind for improving eyesight, tonifying liver of promoting the production of body fluid effect.

Beneficial effect of the present invention:

The all medicines of the present invention share there is removing damp-heat, the effect such as dispelling wind for relieving itching, removing heat from blood are moisturized, antiviral, antiinflammatory, promoting the function of the gallbladder to alleviate jaundice, hepatoprotective, reduction cholate, antihistamine secretion, antiallergic, skin pruritus is caused for treatment hyperbilirubinemia there is significant curative effect, and curative effect is quick, short treating period, cure rate is high, not easily recur, have no side effect, have no adverse reaction.

Detailed description of the invention

Treat the Chinese medicinal formulae that hyperbilirubinemia causes skin pruritus, be made up of the raw material of following weight (g): Radix Saposhnikoviae 15, Herba Schizonepetae 15, Cortex Dictamni 15, Periostracum Cicadae 10, Radix Angelicae Sinensis 10, Herba Ephedrae 6, Zornia diphylla (Linn.) Pers. 9, Radix Paeoniae Rubra 4, Pericarpium Granati 8, Radix Glycyrrhizae 10, Radix Bupleuri 10, Herba Artemisiae Scopariae 10, Radix Curcumae 10, Flos Campsis 7, Rhizoma Polygoni Cuspidati 10, Radix Et Rhizoma Rhei 6, Rabdosia rubescens 16, Fructus Schisandrae Chinensis 10, Folium Lycii 14, Radix Sophorae Flavescentis 10, Herba Lysimachiae 10, propolis 10.

Model case

Case 1: Wang, man, 46 years old.Suffer from hyperbilirubinemia the year before, then cause skin rubefaction, itch.Be little pimple during onset, outwards expand gradually, rounded or multi-ring shape, has pimple, vesicle in surrounding, the ring-shaped edge above surface of incrustation or squama composition, boundary is clear, repeatedly through scratching, then flaring is dissipated to consequent, both shoulders limit, more scratches and more itches, and does not touchingly heal.Once took plurality of Chinese preparation, it is invalid to take.December in 2011 starts to take decoction of the present invention on the 10th, and after taking 3 days, pruritus alleviates, and continues to take 5 days, and skin recovers normal, does not recur.

Case 2: Liu, man, 12 years old.On March 22nd, 2011 causes skin to occur welt, flushing speckle because suffering from hyperbilirubinemia, differs in size, different.Whole body distributes, and is many especially with face, buttocks, lower abdomen, pruritus.When itching very, both hands are scooped up and are scratched, dysphoria.Loss of appetite, once with antiallergic agent treatment, weary effect.Arrive again the county hospital dermatological treatment a few days, invalid.On April 15th, 2011 starts to take granule of the present invention, and after taking 2 days, pruritus alleviates, spirit, appetite amelioration, and after continuing to take 6 days, pruritus disappears, then has no outbreak.

Case 3: grandson, female, 33 years old, suffer from hyperbilirubinemia more than 3 years, cause skin pruritus neck, extremity play welt, pruritus recurrent exerbation, after taking the medicines such as hismanal, erythra can disappear, and itches and also subtracts, but recur again after drug withdrawal, has had a strong impact on work and life.On August 6th, 2011 starts to take pill of the present invention, after taking 4 days, itches and subtracts, and after continuing to take 7 days, all diseases are eliminated, and follows up a case by regular visits to 1 year without recurrence.

Claims

1. treat the Chinese medicine that hyperbilirubinemia causes skin pruritus for one kind, it is characterized in that, be made up of the raw material of following weight portion: Radix Saposhnikoviae 10-15, Herba Schizonepetae 15-20, Cortex Dictamni 12-16, Periostracum Cicadae 8-12, Radix Angelicae Sinensis 10-15, Herba Ephedrae 4-8, Zornia diphylla (Linn.) Pers. 7-11, Radix Paeoniae Rubra 3-5, Pericarpium Granati 6-12, Radix Glycyrrhizae 10-15, Radix Bupleuri 5-10, Herba Artemisiae Scopariae 8-12, Radix Curcumae 9-13, Flos Campsis 5-10, Rhizoma Polygoni Cuspidati 10-15, Radix Et Rhizoma Rhei 5-10, Rabdosia rubescens 14-18, Fructus Schisandrae Chinensis 10-15, Folium Lycii 11-17, Radix Sophorae Flavescentis 8-12, Herba Lysimachiae 5-10, propolis 10-15.

2. according to claim 1ly a kind ofly treat the Chinese medicine that hyperbilirubinemia causes skin pruritus, it is characterized in that, be made up of the raw material of following weight portion: Radix Saposhnikoviae 15, Herba Schizonepetae 15, Cortex Dictamni 15, Periostracum Cicadae 10, Radix Angelicae Sinensis 10, Herba Ephedrae 6, Zornia diphylla (Linn.) Pers. 9, Radix Paeoniae Rubra 4, Pericarpium Granati 8, Radix Glycyrrhizae 10, Radix Bupleuri 10, Herba Artemisiae Scopariae 10, Radix Curcumae 10, Flos Campsis 7, Rhizoma Polygoni Cuspidati 10, Radix Et Rhizoma Rhei 6, Rabdosia rubescens 16, Fructus Schisandrae Chinensis 10, Folium Lycii 14, Radix Sophorae Flavescentis 10, Herba Lysimachiae 10, propolis 10.

3. treatment hyperbilirubinemia according to claim 1 and 2 causes the Chinese medicine of skin pruritus, it is characterized in that, its preparation process is as follows: take said medicine mix homogeneously by formula proportion, be ground into fine powder, become decoction, tablet, powder, pill, granule or capsule by conventional pharmaceutical processes.