CN1927279A - Chinese medicine composition for treating skin disease - Google Patents
Chinese medicine composition for treating skin disease Download PDFInfo
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- CN1927279A CN1927279A CNA2006101128667A CN200610112866A CN1927279A CN 1927279 A CN1927279 A CN 1927279A CN A2006101128667 A CNA2006101128667 A CN A2006101128667A CN 200610112866 A CN200610112866 A CN 200610112866A CN 1927279 A CN1927279 A CN 1927279A
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Abstract
The invention relates to a Chinese medicinal composition for the treatment of skin diseases including skin pruritus of elderly people, acne, eczema, allergic urticaria and erythra, the composition can be The medicament can be prepared into any of the clinically usable dosage forms.
Description
Technical field:
The present invention relates to dermopathic Chinese medicine composition of a kind of treatment and preparation technology thereof, particularly a kind ofly be used for geroderma pruritus, adolescence acne, various eczema, anaphylaxis urticaria and erythra, speckle, the prescription and the preparation technology thereof of disease such as ooze out.
Background technology:
Geroderma pruritus, adolescence acne, various eczema, anaphylaxis urticaria and erythra, speckle, ooze out etc. disease be clinically see that symptom, the traditional Chinese medical science often take that relieving the exterior syndrome dispels the wind more, the means of clearing away heat and eliminating dampness, the skin moistening of invigorating blood circulation treat it, and are and evident in efficacy.But shortcomings such as in the practice, onset is slow because many Chinese medicines have, the course of treatment is long have a strong impact on its clinical practice.
Chinese medicine composition of the present invention can collect the elite and thick the putting of medicine, is easy to dissolving and absorption, and curative effect is fast, and administration time is short, and therefore, curative effect is better.
The pure Chinese medicine composition and the multiple appropriate formulation thereof of disease such as the purpose of this invention is to provide and a kind ofly be used for geroderma pruritus, adolescence acne, various eczema, anaphylaxis urticaria and erythra, speckle, ooze out, said preparation is rapid-action, evident in efficacy, is worthy of popularization.
Summary of the invention:
The present invention relates to a kind of prescription and preparation technology thereof of Chinese medicine preparation, it is characterized in that, the preparation of per 1000 dosage units in basic side is prepared from by following proportion raw material:
50～200 parts of 50～200 parts of Rhizoma Chuanxiongs of 50～200 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum
25～100 parts of 25～100 parts of clean Periostracum Cicadaes of 50～200 portions of Bombyx Batryticatus of Radix Saposhnikoviae
50～200 parts of 15～60 parts of Radix Sophorae Flavescentiss of 25～100 portions of Radix Gentianaes of Radix Et Rhizoma Rhei.
Preferably:
100 parts of 100 parts of Rhizoma Chuanxiongs of 100 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum
50 parts of 50 parts of clean Periostracum Cicadaes of 100 portions of Bombyx Batryticatus of Radix Saposhnikoviae
100 parts of 30 parts of Radix Sophorae Flavescentiss of 50 portions of Radix Gentianaes of Radix Et Rhizoma Rhei.
The preparation of per 1000 dosage units of the present invention side of deriving a is prepared from by following proportion raw material:
50～200 parts of 50～200 parts of Rhizoma Chuanxiongs of 50～200 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum
25～100 parts of 25～100 parts of clean Periostracum Cicadaes of 50～200 portions of Bombyx Batryticatus of Radix Saposhnikoviae
50～200 parts of 15～60 parts of Radix Sophorae Flavescentiss of 25～100 portions of Radix Gentianaes of Radix Et Rhizoma Rhei
20～80 parts of 50～200 parts of SHANZHIZI of 50～200 portions of cercis of Radix Rehmanniae mustard
15～60 parts of 25～100 parts of Radix Scutellariaes of 50～200 parts of Cortex Lycii of Rhizoma Atractylodis.
Preferably:
100 parts of 100 parts of Rhizoma Chuanxiongs of 100 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum
50 parts of 50 parts of clean Periostracum Cicadaes of 100 portions of Bombyx Batryticatus of Radix Saposhnikoviae
100 parts of 30 parts of Radix Sophorae Flavescentiss of 50 portions of Radix Gentianaes of Radix Et Rhizoma Rhei
40 parts of 100 parts of SHANZHIZI of 100 portions of cercis of Radix Rehmanniae mustard
30 parts of 50 parts of Radix Scutellariaes of 100 parts of Cortex Lycii of Rhizoma Atractylodis.
The preparation of per 1000 dosage units of the present invention side of deriving b is prepared from by following proportion raw material:
50～200 parts of 50～200 parts of Rhizoma Chuanxiongs of 50～200 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum
25～100 parts of 25～100 parts of clean Periostracum Cicadaes of 50～200 portions of Bombyx Batryticatus of Radix Saposhnikoviae
50～200 parts of 15～60 parts of Radix Sophorae Flavescentiss of 25～100 portions of Radix Gentianaes of Radix Et Rhizoma Rhei
20～80 parts of 50～200 parts of SHANZHIZI of 50～200 portions of cercis of Radix Scrophulariae mustard
8～32 parts of 25～100 portions of Rhizoma Coptidis of 43.5～174 parts of Cortex Lycii of Cortex Magnoliae Officinalis.
Preferably:
100 parts of 100 parts of Rhizoma Chuanxiongs of 100 parts of Radix Angelicae Sinensis of Semen Sesami Nigrum
50 parts of 50 parts of clean Periostracum Cicadaes of 100 portions of Bombyx Batryticatus of Radix Saposhnikoviae
100 parts of 30 parts of Radix Sophorae Flavescentiss of 50 portions of Radix Gentianaes of Radix Et Rhizoma Rhei
40 parts of 100 parts of SHANZHIZI of 100 portions of cercis of Radix Scrophulariae mustard
16 parts of 50 portions of Rhizoma Coptidis of 87 parts of Cortex Lycii of Cortex Magnoliae Officinalis.
Semen Sesami Nigrum, Radix Rehmanniae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Rhizoma Atractylodis are principal agent in the raw material that the present invention adopts, and have the function that YIN nourishing hemopoietic, collateral dredging are invigorated blood circulation; With Herba Schizonepetae, Radix Saposhnikoviae, Bombyx Batryticatus, Periostracum Cicadae is that accessory drugs makes the skin space between skin and muscles dredge thoroughly the wet and relieving itching with the Eradicates air slaking; With Radix Sophorae Flavescentis, Radix Gentianae, SHANZHIZI, Radix Scutellariae, Radix Et Rhizoma Rhei, Cortex Lycii is adjuvant drug, with the heresy of eliminating damp-heat, removes skin turgor, oozes out all diseases.All medicine combinations are total: mediation skin space between skin and muscles is relieving itching with Eradicates wind; Clearing away heat-damp and promoting diuresis and remove crimson disease of oozing out; Moisten and blood and promote skin metabolism, with repair all as skin lesion see disease.
More than form to be by weight as proportioning, when producing, can increase or reduce according to corresponding proportion, as large-scale production can be unit with the kilogram, or be unit with the ton, small-scale production can be unit with the milligram also, weight can increase or reduce, but the constant rate of the raw medicinal herbs weight proportion between each composition.
The raw material of Chinese medicine of said ratio extracts processing through new technology of the present invention, obtain the active constituents of medicine of preparation of the present invention, add suitable excipient as required and make suitable medicinal any dosage form, said preparation can be multiple suitable dosage forms such as capsule, tablet, powder.
The specific embodiment:
Further specify the present invention by the following examples, include but not limited to the following example.
Embodiment 1:
The preparation method of powder of the present invention:
Prescription:
Semen Sesami Nigrum 100g Radix Angelicae Sinensis 100g Rhizoma Chuanxiong 100g
The clean Periostracum Cicadae 50g of Radix Saposhnikoviae 100g Bombyx Batryticatus 50g
Radix Et Rhizoma Rhei 50g Radix Gentianae 30g Radix Sophorae Flavescentis 100g
Make 1000g
Preparation method:
(1) get Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Saposhnikoviae medical material and directly be ground into fine powder, standby;
(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18～1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50～80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15～1.30 (50), drying, water extract;
(3) above active component is merged mixing, add suitable adjuvant as required, make powder with the galenic pharmacy routine techniques.
Embodiment 2:
The preparation method of capsule of the present invention:
Prescription:
Semen Sesami Nigrum 100g Radix Angelicae Sinensis 100g Rhizoma Chuanxiong 100g
The clean Periostracum Cicadae 50g of Radix Saposhnikoviae 100g Bombyx Batryticatus 50g
Radix Et Rhizoma Rhei 50g Radix Gentianae 30g Radix Sophorae Flavescentis 100g
Make 1000
Preparation method:
(1) get Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Saposhnikoviae medical material and directly be ground into fine powder, standby;
(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18～1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50～80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15～1.30 (50), drying, water extract;
(3) above active component is merged mixing, add suitable adjuvant as required, make capsule with the galenic pharmacy routine techniques
Embodiment 3:
The preparation method of tablet of the present invention:
Prescription:
Semen Sesami Nigrum 100g Radix Angelicae Sinensis 100g Rhizoma Chuanxiong 100g
The clean Periostracum Cicadae 50g of Radix Saposhnikoviae 100g Bombyx Batryticatus 50g
Radix Et Rhizoma Rhei 50g Radix Gentianae 30g Radix Sophorae Flavescentis 100g
Make 1000
Preparation method:
(1) get Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Saposhnikoviae medical material and directly be ground into fine powder, standby;
(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18～1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50～80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15～1.30 (50), drying, water extract;
(3) above active component is merged mixing, add suitable adjuvant as required, make tablet with the galenic pharmacy routine techniques.
Claims (8)
1, a kind ofly is used for dermopathic Chinese medicine preparation, it is characterized in that: according to weight proportion, it is by Semen Sesami Nigrum 50～200, Radix Angelicae Sinensis 50～200, Rhizoma Chuanxiong 50～200, Radix Saposhnikoviae 50～200, Bombyx Batryticatus 25～100, clean Periostracum Cicadae 25～100, Radix Et Rhizoma Rhei 25～100, Radix Gentianae 15～60, Radix Sophorae Flavescentis 50～200 are for basic side or be equipped with other Chinese medicines and generate the sides of deriving and be made.
2, the Chinese medicine preparation of claim 1 is characterized in that, described basic side's proportioning is: 100 parts of Semen Sesami Nigrums, 100 parts of Radix Angelicae Sinensis, 100 parts of Rhizoma Chuanxiongs, 100 parts of Radix Saposhnikoviaes, 50 parts of Bombyx Batryticatus, 50 parts of clean Periostracum Cicadaes, 50 parts of Radix Et Rhizoma Rhei, 30 parts of Radix Gentianaes, 100 parts of Radix Sophorae Flavescentiss.
3, the Chinese medicine preparation of claim 1 is characterized in that, the proportioning of the described side of deriving is:
The basic side of A adds 100 parts of Radix Rehmanniae, 100 parts in cercis mustard, 40 parts of SHANZHIZI, 100 parts of Rhizoma Atractylodis, 50 parts of Cortex Lycii, 30 parts of Radix Scutellariaes;
The basic side of B is with 100 parts of Radix Scrophulariaes, 100 parts in cercis mustard, 40 parts of SHANZHIZI, 87 parts of Cortex Magnoliae Officinalis, 50 parts of Cortex Lycii, 16 parts of Rhizoma Coptidis.
4, the Chinese medicine preparation of claim 1 is characterized in that, is described raw material of Chinese medicine is extracted processing or directly beats powder, obtains active component, adds suitable adjuvant as required, makes clinical needed dosage form with the galenic pharmacy routine techniques.
5, the Chinese medicine preparation of claim 4 is characterized in that:
The preparation process of described capsule is as follows: with above-mentioned gained active component, add a certain amount of filler, correctives, lubricant, granulate, promptly get capsule;
The preparation method of tablet is as follows: with above-mentioned gained active component, adds a certain amount of filler, correctives, lubricant, disintegrating agent, granulates, and drying, tabletting promptly gets tablet.
6, the Chinese medicine preparation of claim 5 is characterized in that:
Described filler is selected from one or more the mixture in lactose, sucrose, dextrin, starch, microcrystalline Cellulose, mannitol, pregelatinized Starch, sorbitol, the xylitol etc.;
Described correctives one of is selected from Rhizoma et radix valerianae, Fructus Pruni pseudocerasi, Fructus Vitis viniferae, Fructus Citri tangerinae, Fructus Citri Limoniae, Herba Menthae, Fructus Fragariae Ananssae, Fructus Musae, Fructus Ananadis comosi, honey peach essence, maltose alcohol, saccharin sodium, protein sugar, sucrose, aspartame, the stevioside or wherein several mixture;
Suitable lubricant comprises wherein one or more such as magnesium stearate, Pulvis Talci, micropowder silica gel.
7, the preparation method of claim 6 is characterized in that: the prescription of the preparation of making is respectively:
The a Semen Sesami Nigrum, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Saposhnikoviae, Bombyx Batryticatus, clean Periostracum Cicadae, Radix Et Rhizoma Rhei, Radix Gentianae, Radix Sophorae Flavescentis;
The b Semen Sesami Nigrum, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Saposhnikoviae, Bombyx Batryticatus, clean Periostracum Cicadae, Radix Et Rhizoma Rhei, Radix Gentianae, Radix Sophorae Flavescentis, Radix Rehmanniae, cercis mustard, SHANZHIZI, Rhizoma Atractylodis, Cortex Lycii, Radix Scutellariae;
The c Semen Sesami Nigrum, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Saposhnikoviae, Bombyx Batryticatus, clean Periostracum Cicadae, Radix Et Rhizoma Rhei, Radix Gentianae, Radix Sophorae Flavescentis, Radix Scrophulariae, cercis mustard, SHANZHIZI, Cortex Magnoliae Officinalis, Cortex Lycii, Rhizoma Coptidis.
8, the application of the Chinese medicine preparation of claim 1 in the medicine of diseases such as preparing treatment geroderma pruritus, adolescence acne, various eczema, anaphylaxis urticaria and erythra, speckle, ooze out.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006101128667A CN1927279A (en) | 2006-09-06 | 2006-09-06 | Chinese medicine composition for treating skin disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2006101128667A CN1927279A (en) | 2006-09-06 | 2006-09-06 | Chinese medicine composition for treating skin disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1927279A true CN1927279A (en) | 2007-03-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2006101128667A Pending CN1927279A (en) | 2006-09-06 | 2006-09-06 | Chinese medicine composition for treating skin disease |
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| CN (1) | CN1927279A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101966329A (en) * | 2010-09-29 | 2011-02-09 | 安政权 | Medicament for treating rash |
| CN102641378A (en) * | 2012-05-03 | 2012-08-22 | 刘正殿 | Drug for curing dematoses |
| CN104997972A (en) * | 2015-08-03 | 2015-10-28 | 陈永学 | Traditional Chinese medicine preparation for treating radiodermatitis |
| CN106727026A (en) * | 2017-01-16 | 2017-05-31 | 四川新绿色药业科技发展有限公司 | A kind of Chinese medicine acne-removing composition and its application |
| CN111544497A (en) * | 2020-05-14 | 2020-08-18 | 云南省中医医院(云南中医药大学第一附属医院) | A Chinese medicinal ointment for treating infantile dermatoses |
-
2006
- 2006-09-06 CN CNA2006101128667A patent/CN1927279A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101966329A (en) * | 2010-09-29 | 2011-02-09 | 安政权 | Medicament for treating rash |
| CN102641378A (en) * | 2012-05-03 | 2012-08-22 | 刘正殿 | Drug for curing dematoses |
| CN104997972A (en) * | 2015-08-03 | 2015-10-28 | 陈永学 | Traditional Chinese medicine preparation for treating radiodermatitis |
| CN106727026A (en) * | 2017-01-16 | 2017-05-31 | 四川新绿色药业科技发展有限公司 | A kind of Chinese medicine acne-removing composition and its application |
| CN106727026B (en) * | 2017-01-16 | 2020-05-22 | 四川新绿色药业科技发展有限公司 | Traditional Chinese medicine acne-removing composition and application thereof |
| CN111544497A (en) * | 2020-05-14 | 2020-08-18 | 云南省中医医院(云南中医药大学第一附属医院) | A Chinese medicinal ointment for treating infantile dermatoses |
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| Date | Code | Title | Description |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
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Application publication date: 20070314 |