CN1927366A - Traditional Chinese medicine composition for treating chronic enterogastritis - Google Patents
Traditional Chinese medicine composition for treating chronic enterogastritis Download PDFInfo
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- CN1927366A CN1927366A CN 200610112876 CN200610112876A CN1927366A CN 1927366 A CN1927366 A CN 1927366A CN 200610112876 CN200610112876 CN 200610112876 CN 200610112876 A CN200610112876 A CN 200610112876A CN 1927366 A CN1927366 A CN 1927366A
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Abstract
The invention relates to a Chinese medicinal composition and preparing process thereof, more specifically a medicament for treating chronic enteritis, stomach and intestine functional disturbance, abdominal distention, maldigestion, loose stool and limb cold. The medicament can be prepared into any of the clinically usable dosage forms.
Description
Technical field:
The present invention relates to a kind of Chinese medicine composition and preparation technology thereof, be particularly related to a kind of being seen abdominal distention of chronic enteritis, gastrointestinal dysfunction, pain, dyspepsia, diarrhoea loose stool that is used for deficiency of spleen-YANG and kidneyYANG, limbs are not warm, waist abdomen fear of cold, the prescription and the preparation technology thereof of disease such as diarrhea just before dawn.
Background technology:
The chronic enteritis of deficiency of spleen-YANG and kidneyYANG, the being seen abdominal distention of gastrointestinal dysfunction, pain, dyspepsia, diarrhoea loose stool, limbs are not warm, waist abdomen fear of cold, disease such as diarrhea is the clinical symptom of seeing more just before dawn, the traditional Chinese medical science often takes gas in the temperature compensation, fortuneization cold-damp, pain relieving antidiarrheal means that it is treated, and evident in efficacy.But shortcomings such as in the practice, onset is slow because many Chinese medicines have, the course of treatment is long have a strong impact on its clinical practice.
Chinese medicine composition of the present invention can collect the elite and thick the putting of medicine, is easy to dissolving and absorption, and curative effect is fast, and administration time is short, and therefore, curative effect is better.
The purpose of this invention is to provide a kind of being seen abdominal distention of chronic enteritis, gastrointestinal dysfunction, pain, dyspepsia, diarrhoea loose stool that is used for deficiency of spleen-YANG and kidneyYANG, limbs are not warm, waist abdomen fear of cold, the pure Chinese medicine composition and the multiple appropriate formulation thereof of disease such as diarrhea just before dawn, said preparation is rapid-action, evident in efficacy, is worthy of popularization.
Summary of the invention:
The present invention relates to a kind of prescription and preparation technology thereof of Chinese medicine preparation, it is characterized in that, the preparation of per 1000 dosage units in basic side is prepared from by following proportion raw material:
50~200 parts of 50~200 parts of Fructus Amomis of 100~400 parts of Rhizoma Alpiniae Officinarum of the Radix Astragali
50~200 parts of 50~200 parts of Radix Aconiti Lateralis Preparata of 50~200 portions of Radix Paeoniae Albas of the Radix Aucklandiae
25~100 parts of 10~40 parts of Pericarpium Papaveriss of Rhizoma Coptidis 15~60 share tea.
Preferably:
100 parts of 100 parts of Fructus Amomis of 200 parts of Rhizoma Alpiniae Officinarum of the Radix Astragali
100 parts of 100 parts of Radix Aconiti Lateralis Preparata of 100 portions of Radix Paeoniae Albas of the Radix Aucklandiae
50 parts of 20 parts of Pericarpium Papaveriss of Rhizoma Coptidis 30 share tea.
The preparation of per 1000 dosage units of the present invention side of deriving a is prepared from by following proportion raw material:
50~200 parts of 50~200 parts of Fructus Amomis of 100~400 parts of Rhizoma Alpiniae Officinarum of the Radix Astragali
50~200 parts of 50~200 parts of Radix Aconiti Lateralis Preparata of 50~200 portions of Radix Paeoniae Albas of the Radix Aucklandiae
25~100 parts of 10~40 parts of Pericarpium Papaveriss of Rhizoma Coptidis 15~60 share tea
50~200 parts of 50~200 parts of Radix Puerariaes of 50~200 parts of Radix Saposhnikoviaes of Rhizoma Atractylodis.
Preferably:
100 parts of 100 parts of Fructus Amomis of 200 parts of Rhizoma Alpiniae Officinarum of the Radix Astragali
100 parts of 100 parts of Radix Aconiti Lateralis Preparata of 100 portions of Radix Paeoniae Albas of the Radix Aucklandiae
50 parts of 20 parts of Pericarpium Papaveriss of Rhizoma Coptidis 30 share tea
100 parts of 100 parts of Radix Puerariaes of 100 parts of Radix Saposhnikoviaes of Rhizoma Atractylodis.
The preparation of per 1000 dosage units of the present invention side of deriving b is prepared from by following proportion raw material:
50~200 parts of 50~200 parts of Fructus Amomis of 100~400 parts of Rhizoma Alpiniae Officinarum of the Radix Astragali
50~200 parts of 50~200 parts of Radix Aconiti Lateralis Preparata of 50~200 portions of Radix Paeoniae Albas of the Radix Aucklandiae
25~100 parts of 10~40 parts of Pericarpium Papaveriss of Rhizoma Coptidis 15~60 share tea
25~100 parts of 44.5~178 parts of Rhizoma Cimicifugaes of 43.5~174 portions of Rhizoma Et Radix Notopterygiis of Cortex Magnoliae Officinalis.
Preferably:
100 parts of 100 parts of Fructus Amomis of 200 parts of Rhizoma Alpiniae Officinarum of the Radix Astragali
100 parts of 100 parts of Radix Aconiti Lateralis Preparata of 100 portions of Radix Paeoniae Albas of the Radix Aucklandiae
50 parts of 20 parts of Pericarpium Papaveriss of Rhizoma Coptidis 30 share tea
50 parts of 89 parts of Rhizoma Cimicifugaes of 87 portions of Rhizoma Et Radix Notopterygiis of Cortex Magnoliae Officinalis.
In more than forming, the weight of medicine is calculated with crude drug, and per 1 part can be 1 gram, also can be kilogram or ton, if be unit with gram, this prescription composition can be made into 1000 doses of pharmaceutical preparatioies.Described 1000 doses of fingers, the final drug preparation of making, as make granule 1000g etc., also can make big packing as granule, as 100~500 bags, specifically can be 100 bags, 125 bags, 200 bags, 250 bags, 500 bags etc., every bag can be used as taking dose 1 time.
More than form, can be made into the preparation of 50~1000 taking doses,, make 125 bags, take 1~2 bag at every turn, can take altogether 62.5~125 times as granule.
More than form to be by weight as proportioning, when producing, can increase or reduce according to corresponding proportion, as large-scale production can be unit with the kilogram, or be unit with the ton, small-scale production can be unit with the milligram also, weight can increase or reduce, but the constant rate of the raw medicinal herbs weight proportion between each composition.
The raw material of Chinese medicine of said ratio extracts processing through new technology of the present invention, obtain the active constituents of medicine of preparation of the present invention, add suitable excipient as required and make suitable medicinal any dosage form, said preparation can be multiple suitable dosage forms such as capsule, granule, tablet, powder.
The specific embodiment:
Further specify the present invention by the following examples, include but not limited to the following example.
Embodiment 1:
The preparation method of granule of the present invention:
Prescription:
Radix Astragali 500g Rhizoma Alpiniae Officinarum 250g Fructus Amomi 250g
Radix Aucklandiae 250g Radix Paeoniae Alba 250g Radix Aconiti Lateralis Preparata 250g
Rhizoma Coptidis 75g catechu 50g foxtail millet shell 125g
Make 1000g
Preparation method:
(1) get the Radix Aucklandiae, Radix Aconiti Lateralis Preparata, catechu, Pericarpium Papaveris medical material and directly be ground into fine powder, standby;
(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18~1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50~80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15~1.30 (50), drying, water extract;
(3) above active component is merged mixing, add aspartame 5.0g, dextrin 200.0g, granulate, drying sprays into essence 5.0g, promptly gets granule 1000g.
Embodiment 2:
The preparation method of capsule of the present invention:
Prescription:
Radix Astragali 200g Rhizoma Alpiniae Officinarum 100g Fructus Amomi 100g
Radix Aucklandiae 100g Radix Paeoniae Alba 100g Radix Aconiti Lateralis Preparata 100g
Rhizoma Coptidis 30g catechu 20g Pericarpium Papaveris 50g
Make 1000
Preparation method:
(1) get the Radix Aucklandiae, Radix Aconiti Lateralis Preparata, catechu, Pericarpium Papaveris medical material and directly be ground into fine powder, standby;
(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18~1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50~80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15~1.30 (50), drying, water extract;
(3) above active component is merged mixing, dry, be made into 1000 of capsules according to the pharmaceutics routine techniques.
Embodiment 3:
The preparation method of tablet of the present invention:
Prescription:
Radix Astragali 200g Rhizoma Alpiniae Officinarum 100g Fructus Amomi 100g
Radix Aucklandiae 100g Radix Paeoniae Alba 100g Radix Aconiti Lateralis Preparata 100g
Rhizoma Coptidis 30g catechu 20g Pericarpium Papaveris 50g
Make 1000
Preparation method:
(1) get the Radix Aucklandiae, Radix Aconiti Lateralis Preparata, catechu, Pericarpium Papaveris medical material and directly be ground into fine powder, standby;
(2) get the residue medical material, extracting in water 2 times, amount of water are 8 times, each extraction time is 1.5 hours, and merge extractive liquid, filters, filtrate decompression is concentrated into the clear paste of relative density 1.18~1.22 (50 ℃ of surveys), put coldly, add ethanol and make and contain alcohol amount and reach 50~80%, stir evenly, left standstill 24 hours, get supernatant and reclaim ethanol to be concentrated into relative density be 1.15~1.30 (50), drying, water extract;
(3) above active component is merged mixing, dry, be made into 1000 in tablet according to the pharmaceutics routine techniques.
Claims (8)
1, a kind of Chinese medicine preparation that is used for chronic enterogastritis, it is characterized in that: according to weight proportion, it is by the Radix Astragali 100~400, Rhizoma Alpiniae Officinarum 50~200, Fructus Amomi 50~200, the Radix Aucklandiae 50~200, the Radix Paeoniae Alba 50~200, Radix Aconiti Lateralis Preparata 50~200, Rhizoma Coptidis 15~60, catechu 10~40, Pericarpium Papaveris 25~100 are for basic side or be equipped with other Chinese medicines and generate the sides of deriving and be made.
2, the Chinese medicine preparation of claim 1 is characterized in that, described basic side's proportioning is: 200 parts of the Radixs Astragali, 100 parts of Rhizoma Alpiniae Officinarum, 100 parts of Fructus Amomis, 100 parts of the Radix Aucklandiae, 100 parts of the Radix Paeoniae Albas, 100 parts of Radix Aconiti Lateralis Preparata, 30 parts of Rhizoma Coptidis, 20 parts in catechu, 50 parts of Pericarpium Papaveriss.
3, the Chinese medicine preparation of claim 1 is characterized in that, the proportioning of the described side of deriving is:
The basic side of A adds 100 parts of Rhizoma Atractylodis, 100 parts of Radix Saposhnikoviaes, 100 parts of Radix Puerariaes;
The basic side of B adds 87 parts of Cortex Magnoliae Officinalis, 89 parts of Rhizoma Et Radix Notopterygiis, 50 parts of Rhizoma Cimicifugaes.
4, the Chinese medicine preparation of claim 1 is characterized in that, is described raw material of Chinese medicine is extracted processing, obtains active component, adds suitable adjuvant as required, makes clinical needed dosage form with the galenic pharmacy routine techniques.
5, the Chinese medicine preparation of claim 4 is characterized in that:
The preparation process of described granule is as follows: with above-mentioned extract obtained, add a certain amount of filler, correctives, lubricant, granulate, promptly get granule;
The preparation method of tablet is as follows: with above-mentioned extract obtained, adds a certain amount of filler, correctives, lubricant, disintegrating agent, granulates, and drying, tabletting promptly gets tablet.
6, the Chinese medicine preparation of claim 5 is characterized in that:
Described filler is selected from one or more the mixture in lactose, sucrose, dextrin, starch, microcrystalline Cellulose, mannitol, pregelatinized Starch, sorbitol, the xylitol etc.;
Described correctives one of is selected from Rhizoma et radix valerianae, Fructus Pruni pseudocerasi, Fructus Vitis viniferae, Fructus Citri tangerinae, Fructus Citri Limoniae, Herba Menthae, Fructus Fragariae Ananssae, Fructus Musae, Fructus Ananadis comosi, honey peach essence, maltose alcohol, saccharin sodium, protein sugar, sucrose, aspartame, the stevioside or wherein several mixture;
Suitable lubricant comprises wherein one or more such as magnesium stearate, Pulvis Talci, micropowder silica gel.
7, the preparation method of claim 6 is characterized in that: the prescription of the preparation of making is respectively:
The a Radix Astragali, Rhizoma Alpiniae Officinarum, Fructus Amomi, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix Aconiti Lateralis Preparata, Rhizoma Coptidis, catechu, Pericarpium Papaveris;
The b Radix Astragali, Rhizoma Alpiniae Officinarum, Fructus Amomi, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix Aconiti Lateralis Preparata, Rhizoma Coptidis, catechu, Pericarpium Papaveris, Rhizoma Atractylodis, Radix Saposhnikoviae, Radix Puerariae;
The c Radix Astragali, Rhizoma Alpiniae Officinarum, Fructus Amomi, the Radix Aucklandiae, the Radix Paeoniae Alba, Radix Aconiti Lateralis Preparata, Rhizoma Coptidis, catechu, Pericarpium Papaveris, Cortex Magnoliae Officinalis, Rhizoma Et Radix Notopterygii, Rhizoma Cimicifugae.
8, the Chinese medicine preparation of claim 1 is in the being seen abdominal distention of chronic enteritis, gastrointestinal dysfunction, pain, dyspepsia, the diarrhoea loose stool of preparation treatment deficiency of spleen-YANG and kidneyYANG, and limbs are not warm, waist abdomen fear of cold, the application in the medicine of disease such as diarrhea just before dawn.
Priority Applications (1)
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CN 200610112876 CN1927366A (en) | 2006-09-06 | 2006-09-06 | Traditional Chinese medicine composition for treating chronic enterogastritis |
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CN 200610112876 CN1927366A (en) | 2006-09-06 | 2006-09-06 | Traditional Chinese medicine composition for treating chronic enterogastritis |
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CN 200610112876 Pending CN1927366A (en) | 2006-09-06 | 2006-09-06 | Traditional Chinese medicine composition for treating chronic enterogastritis |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101700296B (en) * | 2009-11-20 | 2012-02-15 | 周云飞 | Chinese herbal preparation for curing gastroenteritis and preparation method thereof |
CN108815461A (en) * | 2018-09-19 | 2018-11-16 | 廖增祥 | A kind of Chinese medicine preparation and preparation method thereof for treating enterogastritis |
-
2006
- 2006-09-06 CN CN 200610112876 patent/CN1927366A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101700296B (en) * | 2009-11-20 | 2012-02-15 | 周云飞 | Chinese herbal preparation for curing gastroenteritis and preparation method thereof |
CN108815461A (en) * | 2018-09-19 | 2018-11-16 | 廖增祥 | A kind of Chinese medicine preparation and preparation method thereof for treating enterogastritis |
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Application publication date: 20070314 |