CN111544497A - A Chinese medicinal ointment for treating infantile dermatoses - Google Patents
A Chinese medicinal ointment for treating infantile dermatoses Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/86—Violaceae (Violet family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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Abstract
The invention discloses a traditional Chinese medicine ointment for treating infant skin diseases, which is prepared from the following raw materials in parts by weight: 18-22 parts of lithospermum, 75-85 parts of radix rehmanniae recen, 10-15 parts of coptis chinensis, 75-85 parts of angelica sinensis, 10-15 parts of polygonum cuspidatum, 22-25 parts of dandelion, 10-15 parts of gentian, 10-15 parts of scutellaria baicalensis, 10-15 parts of phellodendron amurense, 10-15 parts of philippine violet herb, 10-15 parts of radix ampelopsis, 8-12 parts of borneol and 900-1100 parts of vaseline. The traditional Chinese medicine composition has the effects of clearing heat, removing toxicity, removing putrefaction and promoting granulation, and has good curative effects on red buttocks, skin ulcer, eczema sicca, psoriasis and the like of infants.
Description
Technical Field
The invention relates to a traditional Chinese medicine ointment for treating infant skin diseases, and belongs to the technical field of traditional Chinese medicine compositions.
Background
The skin of the infant is thin, the epidermis is a single-pass cell, the thickness is one tenth of that of the skin of an adult, the sweat glands and blood vessels on the skin are not completely developed, the temperature regulation capability is low, and the acid-base control capability is poor; infants have poor skin resistance due to the incomplete immune system.
Under the conditions of high temperature and high humidity in summer, the skin of the infant is easy to grow prickly heat, the skin becomes red when the prickly heat is grown, then red papules or papules with the size similar to that of a needle head appear, and the papules are densely flaky, wherein some papules are purulent; after miliaria occurs, the symptoms of itching and pain are severe, and sometimes a lot of hot and spicy burning pain exists. Still other infants are prone to develop eczema, which is often seen on the head and face, such as forehead, cheeks, crown, and then gradually spread to neck, shoulder, back, buttocks, limbs, and even may spread to the whole body, and at the beginning, the small red papule or erythema may be sporadic or clustered, gradually increase, and small blisters, yellow and white scales and crusts may be seen, and there may be exudative erosion, and secondary infection. The infant is restless and crying at night, which affects sleep and is often itchy everywhere. The redness, swelling and even erosion of the skin of the infant's buttocks in the diaper contact area, diaper dermatitis as an infection, if left untreated, the continued development of exudates with the result that the epidermis falls off, forming ulcers and papules and erythema and is moderate. If not treated in time, the disease develops into more serious ulcer, local infection is caused by skin damage and bacterial reproduction, and septicemia is caused in serious cases.
At present, the main treatments of the skin diseases comprise talcum powder, prickly heat powder, erythromycin ointment, laser treatment and the like, the talcum powder and the prickly heat powder are easily applied to the nasal cavity of a baby, erythromycin has drug resistance, and the laser treatment is expensive, so that the traditional Chinese medicine ointment which can effectively relieve the skin diseases of the baby and has no side effect is urgently needed to be found.
Disclosure of Invention
The invention relates to a traditional Chinese medicine ointment for treating infant skin diseases, which adopts a pure traditional Chinese medicine formula, does not contain any stimulating component, and has the effects of clearing away heat and toxic materials, removing putrefaction and promoting granulation; the traditional Chinese medicine ointment is prepared from the following raw materials in parts by weight: 18-22 parts of lithospermum, 75-85 parts of radix rehmanniae recen, 10-15 parts of coptis chinensis, 75-85 parts of angelica sinensis, 10-15 parts of polygonum cuspidatum, 22-25 parts of dandelion, 10-15 parts of gentian, 10-15 parts of scutellaria baicalensis, 10-15 parts of phellodendron amurense, 10-15 parts of philippine violet herb, 10-15 parts of radix ampelopsis, 8-12 parts of borneol and 900-1100 parts of vaseline.
Preferably, the traditional Chinese medicine ointment is prepared from the following raw materials in parts by weight: 20 parts of lithospermum, 80 parts of radix rehmanniae recen, 12 parts of coptis chinensis, 80 parts of angelica sinensis, 15 parts of polygonum cuspidatum, 24 parts of dandelion, 12 parts of gentian, 12 parts of scutellaria baicalensis, 12 parts of phellodendron, 12 parts of Chinese violet, 12 parts of ampelopsis japonica, 10 parts of borneol and 1000 parts of vaseline.
The preparation method of the ointment comprises the following steps: heating vaseline in a pot to melt, sequentially adding the twelve medicines except radix Arnebiae and Borneolum Syntheticum in the pot, heating with slow fire until the outer part of the medicinal materials is dark brown and the inner part is dark yellow, taking out, stopping heating, adding radix Arnebiae, stirring to make the medicinal liquid red, filtering while hot, cooling to 60-70 deg.C, slowly spreading ground Borneolum Syntheticum, and stirring to obtain 1000 g.
The prescription principle and treatment of the traditional Chinese medicine composition provided by the invention claim that:
square solution: the Jinwanhong paste is a preparation in hospital of traditional Chinese medicine hospital in Yunnan province, is applied to clinical practice for decades, and consists of the medicines of lithospermum, coptis chinensis, radix rehmanniae, angelica, scutellaria baicalensis, polygonum cuspidatum, raw sanguisorba, borneol and the like, wherein the lithospermum has the effects of clearing heat and detoxifying, promoting granulation and healing sore, entering blood, being capable of lowering blood, the coptis chinensis has the effects of clearing heat and drying dampness, purging intense heat and detoxifying, being thick in texture and taste, lowering blood volume to microliter, the radix rehmanniae has the effects of clearing heat; the scutellaria baicalensis clears heat and dries dampness, purges fire and detoxifies, and the raw sanguisorba cools blood and stops bleeding, helps the monarch drug to strengthen the effects of clearing heat and detoxifying, healing sores and relieving pain, and is a ministerial drug; the angelica has the functions of enriching and activating blood, and the giant knotweed has the functions of activating blood and dissolving stasis, and detoxifying and reducing swelling as an adjuvant drug; borneol is used as a guiding drug for relieving orifices, dispersing stagnated fire, removing dirt and turbidity, clearing heat, relieving swelling and alleviating pain. The medicines are combined to have the effects of clearing away heat and toxic materials, removing blood stasis, promoting tissue regeneration, reducing swelling and relieving pain.
The principle of medication is as follows: take proper amount (according to the area of skin lesion) and apply it on the skin lesion 2 times a day.
The preparation method comprises the following steps: heating vaseline in a pot to melt, sequentially adding the above materials except radix Arnebiae and Borneolum Syntheticum in the pot, heating with slow fire until the outer color of the materials turns dark brown and the inner color turns dark yellow, taking out, stopping heating, adding radix Arnebiae, stirring to obtain red medicinal liquid, filtering while hot, cooling to 60-70 deg.C, slowly spreading ground Borneolum Syntheticum, and stirring to obtain 1000 g.
The dispensing principle is as follows: the heat-clearing and detoxicating medicine is added with the dampness-removing astringent medicine.
Treatment claims that: clearing away heat and toxic material, removing necrotic tissue and promoting granulation. Can be used for treating burn, scald, and skin ulcer such as red buttock and pressure sore of infant.
The invention has the beneficial effects that:
the invention adopts a pure traditional Chinese medicine formula, does not contain any stimulating component, is a pure plant formula, has the effects of clearing away heat and toxic materials, removing putrefaction and promoting granulation, and has very good curative effect on treating red buttocks, skin ulcer, xerotic eczema, psoriasis and the like of infants.
Detailed Description
The present invention is further described in detail with reference to the following specific examples, but the scope of the present invention is not limited to the above description.
Example 1
A traditional Chinese medicine ointment for treating infant skin diseases is prepared from the following raw materials in parts by weight: 20g of lithospermum, 80g of radix rehmanniae recen, 12g of coptis chinensis, 80g of angelica sinensis, 15g of polygonum cuspidatum, 24g of dandelion, 12g of gentian, 12g of scutellaria baicalensis, 12g of phellodendron amurense, 12g of herba violae, 12g of radix ampelopsis, 10g of borneol and 1000g of vaseline.
Case 1: patient Liaoxin, woman, 24 days; initial diagnosis in 8 months and 9 days in 2019.
The main complaints are: parents of children patients complain about the pudendum of children patients, and flaky erythema occurs on the hip for 2 days.
Initial diagnosis: when parents of children patients complain about 2 days before treatment and help the children patients to change and wash the diaper at noon, a little erythema appears at the vulva of the children patients, the 'desonide cream' is automatically applied to the skin, and the erythema is improved but not obvious. The diseases are seen as follows: the diaper parts contacted with the pudendum and the buttocks generate large flaky erythema, papular dermatitis at the erythema border, poor sleep, easy adjustment, crying and screaming of the infant patients, no tongue diagnosis, normal fingerprint and smooth and rapid pulse.
And (3) diagnosis:
western medicine: diaper dermatitis
Traditional Chinese medicine: diaper rash
Syndrome of blood-heat accumulation in the skin
Therapeutic method: cool blood, clear heat and remove toxicity. No oral administration, external application: the ointment of example 1 was applied to the skin lesion 5 times a day. Order parents of the sick children to use the diapers with strong water absorption and frequently change the diapers, keep the pudendum of the sick children dry, and puff powder after cleaning. Scalding with soap water and hot water is avoided.
Second diagnosis (2016, 8, 15 days): the parents of the children suffer from complaints and the rash is improved to be normal skin. The ointments of the invention are intended for daily administration. The nursing is as before.
According to the following steps: the ointment of the invention has the effects of clearing away heat and toxic materials and cooling blood. Diaper dermatitis is dermatitis that occurs due to ammonia produced by decomposition of urine by ammonia-producing bacteria in feces on a diaper and the irritant effect of ammonia. The skin of a patient is red in color, blood heat is obviously accumulated in the skin, and the golden kaleidoscope ointment comprises the following medicinal components: baikal skullcap root and Huang Lian can clear heat, dry dampness, purge fire and remove toxicity, and treat carbuncle, swelling, sore and furuncle; the lithospermum has the effects of clearing heat, cooling blood, activating blood, detoxifying and promoting eruption; rehmannia root: clear heat and cool blood. The four medicines are combined to have better effects of clearing heat and removing toxicity, cooling blood and dispelling wind, and are used for treating diaper dermatitis.
Example 2
A traditional Chinese medicine ointment for treating infant skin diseases is prepared from the following raw materials in parts by weight: 18g of lithospermum, 75g of radix rehmanniae recen, 10g of coptis chinensis, 85g of angelica sinensis, 15g of polygonum cuspidatum, 22g of dandelion, 10g of gentian, 10g of scutellaria baicalensis, 10g of phellodendron, 10g of herba violae, 15g of radix ampelopsis, 12g of borneol and 900g of vaseline.
Case 2
The patient is a certain woman for 45 days; initial diagnosis in 2019, 10 and 9 months.
The main complaints are: parents of the sick children complain about the small blisters, crying and crying at night and restlessness on the face and the neck of the sick children. After 3 days, the patients are treated in our hospital with the following symptoms: large red rashes appeared on the face.
And (3) diagnosis:
western medicine: eczema (eczema)
Traditional Chinese medicine: eczema
Syndrome/pattern of blood heat accumulating in skin
Therapeutic method: cool blood, clear heat and remove toxicity. No oral administration, external application: the ointment of example 2 was applied to the skin lesion 5 times a day. Order parents of children to take a bath everyday, keep the skin dry and moist, and avoid using irritant washing and nursing articles.
Second diagnosis (10 months and 15 days in 2019): the parents of the children suffer from complaints and the rash is improved to be normal skin. The ointment of the present invention is used as daily medicine for the same adjustment and care as before.
Example 3
A traditional Chinese medicine ointment for treating infant skin diseases is prepared from the following raw materials in parts by weight: 22g of lithospermum, 85g of radix rehmanniae recen, 15g of coptis chinensis, 75g of angelica sinensis, 15g of polygonum cuspidatum, 25g of dandelion, 15g of gentian, 15g of scutellaria baicalensis, 15g of phellodendron, 15g of herba violae, 10g of radix ampelopsis, 8g of borneol and 1100g of vaseline.
Case 3 patient wu somebody, male, 88 years old; initial diagnosis in 12 months and 14 days in 2018.
The main complaints are: the family members of the patients complain about the flaky ulcer of the buttocks of the patients for half a year.
Initial diagnosis: the family members of the patients describe that after the patients are cerebral infarction before one year, the right limbs of the patients are not flexible, the patients lie in beds at home, the nursing bodies are turned a little, right hip erosion appears before half a year, such as the size of a monobasic coin, the patients gradually deepen, the subjective pain and skin damage increase, the left hip appears in the size of a coin before 3 months, the patients gradually deepen and turn dark red, and the family members can purchase anti-inflammatory ointments such as the Baiduobang emulsifiable paste and the like for external use by themselves, so that the improvement is not obvious. To ask for systemic treatment, go to the outpatient clinic of our hospital. The symptoms are as follows: two ulcers with the size of a coin can be seen on the buttocks at both sides, and the surface is covered with a yellow rotten film, so that the exudation is less. Poor appetite, poor sleep and convenient adjustment. The patient gesture indicates pain. The tongue is red, the coating is thin and yellow, and the pulse is thready and rapid.
And (3) diagnosis:
western medicine: pressure sores
Traditional Chinese medicine: mat sore
Syndrome of yin deficiency and blood heat
Therapeutic method: cool blood, clear heat and remove toxicity, remove putrefaction and promote granulation. No oral administration, external application: the ointment of example 3 was applied to the skin lesion 3 times a day. The affected part is irradiated with infrared ray once a day. External application is continued for 2 weeks. Keeping the affected part dry and clean. Enhancing the nutritional support.
Second diagnosis (1 month and 2 days 2019): the patients' family complaints that the ulcer surface becomes lighter than the front, the yellow rotten membrane disappears, and the color of the wound surface is light red. The ointments of the invention are intended to be used daily; the skin lesions were irradiated with infrared rays once every other day. The nursing is as before. It is used for 1 month.
Three diagnoses (3 months and 5 days in 2019): the patients' family complaints, the ulcer surface basically disappears, and the color of the wound surface is light red. The ointments of the invention are intended to be used daily; the skin lesions were irradiated with infrared rays once every 2 days. The nursing is as before. After 2 weeks, the patient can be cured.
Claims (2)
1. The traditional Chinese medicine ointment for treating the skin diseases of the infants is characterized by being prepared from the following raw materials in parts by weight: 18-22 parts of lithospermum, 75-85 parts of radix rehmanniae recen, 10-15 parts of coptis chinensis, 75-85 parts of angelica sinensis, 10-15 parts of polygonum cuspidatum, 22-25 parts of dandelion, 10-15 parts of gentian, 10-15 parts of scutellaria baicalensis, 10-15 parts of phellodendron amurense, 10-15 parts of philippine violet herb, 10-15 parts of radix ampelopsis, 8-12 parts of borneol and 900-1100 parts of vaseline.
2. The traditional Chinese medicine ointment for treating infant skin diseases according to claim 1, which is prepared from the following raw materials in parts by weight: 20 parts of lithospermum, 80 parts of radix rehmanniae recen, 12 parts of coptis chinensis, 80 parts of angelica sinensis, 15g of polygonum cuspidatum, 24 parts of dandelion, 12 parts of gentian, 12 parts of scutellaria baicalensis, 12 parts of phellodendron, 12 parts of Chinese violet, 12 parts of radix ampelopsis, 10 parts of borneol and 1000 parts of vaseline.
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CN106620539A (en) * | 2017-02-07 | 2017-05-10 | 邹琳 | External ointment for treating skin diseases as well as preparation method and application thereof |
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CN1927279A (en) * | 2006-09-06 | 2007-03-14 | 北京润德康医药技术有限公司 | Chinese medicine composition for treating skin disease |
CN102743484A (en) * | 2012-07-09 | 2012-10-24 | 中南大学湘雅三医院 | Plaster for treating skin disorder and preparation method thereof |
CN106620539A (en) * | 2017-02-07 | 2017-05-10 | 邹琳 | External ointment for treating skin diseases as well as preparation method and application thereof |
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Title |
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