CN100333766C - Medicine for treating dermatopathy and its preparing process - Google Patents
Medicine for treating dermatopathy and its preparing process Download PDFInfo
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- CN100333766C CN100333766C CNB2003101110617A CN200310111061A CN100333766C CN 100333766 C CN100333766 C CN 100333766C CN B2003101110617 A CNB2003101110617 A CN B2003101110617A CN 200310111061 A CN200310111061 A CN 200310111061A CN 100333766 C CN100333766 C CN 100333766C
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- aloe
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- rhizoma coptidis
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Abstract
The present invention relates to a medicine for treating dermatosis and a preparation method thereof. The medicine is a medicament prepared from the raw materials of the following weight compounding ratio: 10 to 100 of coptis, 10 to 100 of corktree bark, 10 to 100 of climbing groundsel, 10 to 95 of Asian puccoon, 10 to 100 of aloe, 500 to 600 of vaseline, 150 to 250 of glycerine and 200 to 500 of sesame oil. The medicine of the present invention has the effects of relieving inflammation, alleviating pain, eliminating dampness, converging, promoting granulation, promoting granulation tissue growth, rapidly healing the wound surface, etc. The clinical application proves that the medicine has obvious curative effects on newborn dermatitis and baby napkin dermatitis. The cure rate is as high as 100%, and simultaneously, the medicine can also be used for 20 cases of bedsore patients (6 cases of I degree, 12 cases of II degree and 3 cases of III degree) 21 cases of scald patients (13 cases of I degree and 8 cases of II degree). The curing time is from 2 to 5 days, the wound healing speed is high, and the scar is small, thereby achieving obvious curative effect. The medicine of the present invention has the advantages of wide medicine sources and low cost, is especially popular with patients, and has high popularization value and application value.
Description
Technical field
The present invention relates to treat dermopathic medicine, specifically is the Chinese patent medicine that feedstock production becomes with the Chinese herbal medicine.The invention still further relates to the preparation method of this medicine.
Background technology
In the disease that neonate and baby are taken place, diaper dermatitis is more common.Because neonate, infant skin are tender and lovely, if diaper change is untimely or when adding with rubberized fabric, Polypropylence Sheet, that the infant buttocks is in for a long time is damp and hot (large and small just soak) state, or, then easily cause dermatitis owing in the infantile diarrhea, stool antibacterial is arranged.Primary disease is sent out well in direct contacts site of diaper such as external genital and buttocks, lower limb and abdomen inboards, infringement is well-defined large stretch of erythema, can there be the minority pimple on the surface, visible vesicle, erosion even ulcer or secondary infection when serious, if curing untimely then the infection increases the weight of, when serious septicemia can take place, cause infant death.The traditional Chinese medical science calls this " diaper dermatitis ".
The medicine of the above-mentioned disease of existing control is to have: with Radix Arnebiae (Radix Lithospermi) frost and Radix Arnebiae (Radix Lithospermi) Ointment in Treatment baby diaper dermatitis; With compound coptis chinensis cream treatment baby diaper dermatitis and children's's diaper dermatitis etc.Healing speed such as these Drug therapys children's diaper dermatitis are 2～27 days, average 13～14 days, and effective percentage 97.%, cure rate 87.1%.And effect is single, can only treat the disease of children's's diaper dermatitis one class.
Summary of the invention
The purpose of this invention is to provide and a kind ofly have antiinflammatory, pain relieving, dampness, convergence granulation promoting, promote the granulation tissue growth, make wound surface effect such as healing rapidly, have no side effect dermopathic medicine of treatment safe in utilization and preparation method thereof.
The main case of solution of the present invention is with principal agent in Rhizoma Coptidis (Rhizoma Coptidis) side of serving as, belongs to cohosh.Rhizoma Coptidis (coptis chinensis Franch) rhizome, has the effect of heat clearing away, dampness at the nature and flavor bitter cold; Containing acetylshikonin (Acetg Ashikonen) in the Radix Arnebiae (Radix Lithospermi) is antimicrobial effective ingredient, be equipped with Cortex Phellodendri, the Herba Senecionis Scandentis of heat clearing away, dampness, Detoxication simultaneously and convergence is arranged, the Aloe of controlling the exudative dermatitis effect can play good synergism.Meet the traditional Chinese medical science " monarch " and combination principle.
Medicine of the present invention is made by following drug component: (consumption is a weight portion)
It is the medicament of being made by the following weight proportion raw material:
Rhizoma Coptidis, Cortex Phellodendri, Herba Senecionis Scandentis various each 10～100, Radix Arnebiae (Radix Lithospermi) 10～95, Aloe 10～100, vaseline 500～600, glycerol 150～250, Oleum Sesami 200～500.
The optimum weight proportioning of medicine of the present invention is:
Rhizoma Coptidis, Cortex Phellodendri, Herba Senecionis Scandentis each 50, Radix Arnebiae (Radix Lithospermi) 30, Aloe 30, vaseline 540, glycerol 200, Oleum Sesami 250.
The preparation method of medicine of the present invention is carried out according to the following steps:
1) earlier Rhizoma Coptidis was soaked 2 days with washing water of rice;
2) Rhizoma Coptidis of above-mentioned immersion and Cortex Phellodendri, Herba Senecionis Scandentis, Radix Arnebiae (Radix Lithospermi) were soaked 3 days with Oleum Sesami, are stirred every day 1 time, place pot internal heating then, filter to above-mentioned medical material " the withered heart " (being that medicine is closely dried-up), remove slag filtrate for later use;
3) the Aloe porphyrize is crossed No. 6 sieve;
4) vaseline is heated to fusing;
5) hot melt vaseline, glycerol and Aloe fine powder are added 2 in proper order) gained filtrate, same direction limit edged is stirred to and coagulates, and packing is promptly.
The clinical practice of medicine of the present invention:
One, case is selected:
Be in hospital and the outpatient service infant, neonate that the age was suffered from diaper dermatitis in 2 days to 8 months for being born and baby be totally 244 examples.
Two, Therapeutic Method:
244 routine infants are divided into two groups at random, at no significant differences such as birth age, severe extents.The treatment group is used each 0.1～0.5 gram of this medicine unguentum, every day 4 times, embrocates the dermatitis happening part.Matched group uses simple Oleum Radix Arnebiae (Oleum Radix Lithospermi), every day 4 times, embrocates the dermatitis happening part.
Three, curative effect is judged:
Recovery from illness---the skin lesion inflammation disappears fully in 5 days;
Produce effects---in 5 days skin lesion disappear＞70%;
Effectively---in 5 days skin lesion disappear＞35%;
Invalid---in 5 days skin lesion disappear＜35%.
Four, result:
The all recoveries from illness in 1～5 day after medication of treatment group, cure rate reaches 100%.After the matched group medication 5 days, cure 24 examples, produce effects 20 examples, effective 26 examples, invalid 46 examples, effective percentage is 60.3%.Learn by statistics and handle X
2=81.48, there is the utmost point significant difference P＜0.001.The 92 routine infants that matched group is not fully recovered are all recoveries from illness in 1～5 day after using medicine of the present invention.
Medicine of the present invention has antiinflammatory, pain relieving, dampness, convergence granulation promoting, promote the granulation tissue growth, make wound surface effect such as healing rapidly, prove through clinical practice, this medicine is used for neonate and the baby napkin dermatitis curative effect is affirmed, cure rate is up to 100%, simultaneously, also be used for 20 routine decubital ulcer patients (I degree 6 examples, II degree 12 examples, III degree 3 examples) and 21 routine scalded patients (I degree 13 examples, II degree 8 examples), healing time is all at 2～5 days, and wound healing is fast, cicatrix is little, has obtained notable therapeutic effect.Medicine medicine of the present invention source is wide, and cost is low, welcome by the patient, and higher popularization and application values is arranged.
The specific embodiment
Embodiment 1:
Get Rhizoma Coptidis, Cortex Phellodendri, each 50 gram of Herba Senecionis Scandentis, Radix Arnebiae (Radix Lithospermi) 30 grams, Aloe 30 grams, vaseline 540 grams, glycerol 200 grams, Oleum Sesami 250 grams.
Preparation according to the following steps:
1) earlier Rhizoma Coptidis was soaked 2 days with washing water of rice;
2) Rhizoma Coptidis of above-mentioned immersion and Cortex Phellodendri, Herba Senecionis Scandentis, Radix Arnebiae (Radix Lithospermi) were soaked 3 days with Oleum Sesami, are stirred every day 1 time, place pot internal heating then, filter to above-mentioned medical material " the withered heart ", remove slag filtrate for later use;
3) the Aloe porphyrize is crossed No. 6 sieve;
4) vaseline is heated to fusing;
5) hot melt vaseline, glycerol and Aloe fine powder are added 2 in proper order) gained filtrate, same direction limit edged is stirred to and coagulates, and packing is promptly.
Embodiment 2:
Claims (3)
1, the dermopathic medicine of a kind of treatment, it is characterized in that it is the medicament of being made by the following weight proportion raw material: Rhizoma Coptidis, Cortex Phellodendri, Herba Senecionis Scandentis each 10～100, Radix Arnebiae (Radix Lithospermi) 10～95, Aloe 10～100, vaseline 500～600, glycerol 150～250, Oleum Sesami 200～500, this medicaments preparation method is: earlier Rhizoma Coptidis was soaked 2 days with washing water of rice, with the Rhizoma Coptidis of soaking, and Cortex Phellodendri, Herba Senecionis Scandentis, Radix Arnebiae (Radix Lithospermi) was soaked 3 days with Oleum Sesami, stirred every day 1 time, place pot internal heating to above-mentioned medical material " the withered heart " then, filter, remove slag filtrate, the Aloe porphyrize is crossed sieve No. 6, vaseline is heated to fusing, with hot melt vaseline, glycerol and Aloe fine powder add in the filtrate in proper order, are stirred to coagulate, promptly.
2, the dermopathic medicine of treatment according to claim 1 is characterized in that the weight proportion of each raw material is: Rhizoma Coptidis, Cortex Phellodendri, Herba Senecionis Scandentis each 50, Radix Arnebiae (Radix Lithospermi) 30, Aloe 30, vaseline 540, glycerol 200, Oleum Sesami 250.
3, the preparation method of the dermopathic medicine of treatment as claimed in claim 1 is characterized in that preparing according to the following steps:
1) earlier Rhizoma Coptidis 10～100 usefulness washing water of rice were soaked 2 days:
2) with the Rhizoma Coptidis of above-mentioned immersion and Cortex Phellodendri each 10～100, Herba Senecionis Scandentis 10～100, Radix Arnebiae (Radix Lithospermi) 10～95 usefulness Oleum Sesami 200～500 soaked 3 days, stirs every day 1 time, places pot internal heating to above-mentioned medical material " the withered heart " then, filtration, remove slag filtrate for later use;
3) Aloe 10～100 porphyrizes are crossed No. 6 sieve;
4) vaseline 500～600 is heated to fusing;
5) hot melt vaseline, glycerol 150～250 and Aloe fine powder are added 2 in proper order) gained filtrate, same direction limit edged is stirred to and coagulates, and packing is promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101110617A CN100333766C (en) | 2003-11-26 | 2003-11-26 | Medicine for treating dermatopathy and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101110617A CN100333766C (en) | 2003-11-26 | 2003-11-26 | Medicine for treating dermatopathy and its preparing process |
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| Publication Number | Publication Date |
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| CN1621074A CN1621074A (en) | 2005-06-01 |
| CN100333766C true CN100333766C (en) | 2007-08-29 |
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| CNB2003101110617A Expired - Fee Related CN100333766C (en) | 2003-11-26 | 2003-11-26 | Medicine for treating dermatopathy and its preparing process |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101148785B (en) * | 2007-10-19 | 2010-05-19 | 东华大学 | Gromwell root medical polypropylene fibre for preventing and curing skin disease, preparation method and application thereof |
| CN103169820A (en) * | 2013-03-16 | 2013-06-26 | 陆芬 | Traditional Chinese medicine external lotion for treating diaper dermatitis of neonates |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100463688C (en) * | 2006-08-25 | 2009-02-25 | 海南新中正制药有限公司 | Ointment with aloe and other five medicinal herbs and its preparation method |
| CN101732472B (en) * | 2008-11-05 | 2012-04-11 | 郭丽 | Chinese ointment for treating pediatric diaper dermatitis |
| CN103142716B (en) * | 2013-03-07 | 2014-06-04 | 林诗莲 | Chinese medicine external lotion for treating infantile eczema |
| CN103989850B (en) * | 2014-06-11 | 2018-04-17 | 王肖茜 | A kind of Chinese herbal medicine extract composition of anti-diaper dermatitis |
| CN107308305B (en) * | 2017-06-02 | 2020-08-04 | 广西大海阳光药业有限公司 | Preparation for treating infantile eczema, dermatitis and infantile eczema |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1181262A (en) * | 1997-10-15 | 1998-05-13 | 重庆同心制药有限公司 | Preparation for treating burns and empyrosis and its preparing process |
| CN1329831A (en) * | 2000-06-17 | 2002-01-09 | 内蒙古苦参生化集团有限责任公司 | Disinfectant and its preparing process |
-
2003
- 2003-11-26 CN CNB2003101110617A patent/CN100333766C/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1181262A (en) * | 1997-10-15 | 1998-05-13 | 重庆同心制药有限公司 | Preparation for treating burns and empyrosis and its preparing process |
| CN1329831A (en) * | 2000-06-17 | 2002-01-09 | 内蒙古苦参生化集团有限责任公司 | Disinfectant and its preparing process |
Non-Patent Citations (1)
| Title |
|---|
| 80种中药水煎液对淋球菌的抑制试验 袁昌衡等，中国医院药学杂志，第17卷第11期 1997 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101148785B (en) * | 2007-10-19 | 2010-05-19 | 东华大学 | Gromwell root medical polypropylene fibre for preventing and curing skin disease, preparation method and application thereof |
| CN103169820A (en) * | 2013-03-16 | 2013-06-26 | 陆芬 | Traditional Chinese medicine external lotion for treating diaper dermatitis of neonates |
| CN103169820B (en) * | 2013-03-16 | 2014-07-23 | 陆芬 | Traditional Chinese medicine external lotion for treating diaper dermatitis of neonates |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1621074A (en) | 2005-06-01 |
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Granted publication date: 20070829 Termination date: 20091228 |