CN101156925A - A traditional Chinese medicine preparation for treating children dermatosis - Google Patents
A traditional Chinese medicine preparation for treating children dermatosis Download PDFInfo
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- CN101156925A CN101156925A CNA2007100699247A CN200710069924A CN101156925A CN 101156925 A CN101156925 A CN 101156925A CN A2007100699247 A CNA2007100699247 A CN A2007100699247A CN 200710069924 A CN200710069924 A CN 200710069924A CN 101156925 A CN101156925 A CN 101156925A
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Abstract
The invention relates to Chinese traditional medicine preparation used for treating the dermatosis of children. The Chinese traditional medicine preparation is the preparation made of raw materials according to the following proportioning by weight: snphora flavescens ait is 20 to 80 parts, amoorcorn tree bark is 20 to 80 parts, fructus cnidii is 20 to 80 parts, fructus kochiae is20 to 80 parts, rhubarb is 10 to 30 parts, radix gentianae is 5 to 20 parts, acorus gramineus soland is 10 to 30 parts, dahurian angelica is 5 to 20 parts, forsythia fruit is 20 to 80 parts, ledebouriella seseloides wolff is 5 to 20parts, honeysuckle flower is 10 to 30 parts, dandelion is 10 to 30 parts, tuckahoe is 20 to 80 parts, and Chinese gall is 5 to 20 parts. The invention chooses natural plants allied with medicinal food as the raw materials, and cures the dermatosis of the children based on the enhancement of the combination drug medical function mechanism on the medical function, the Chinese traditional medicine preparation has no toxic side effect to the skin, and plays the nourishing and moistening effect;the Chinese traditional medicine preparation can not result in any pain when the child bathes and uses the Chinese traditional medicine preparation,and the operation is convenient; the Chinese traditional medicine preparation has the good curing effect on the dermatosis of the children, especially on the infantile eczema, and the recurrence is not easy after being cured.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, relate in particular to a kind of Chinese medicine preparation that is used for the treatment of children ' s dermatosis, belong to medicine and technical field of chemistry.
Background technology
Skin is the outermost layer organ of human body, and it is covered with whole body.Skin not only has functions such as sensation, secretion, drainage, breathing, regulate body temperature, absorption, also human body is had protective effect.Child's skin softness is weak, delicate, resistance is poor, is easy to infected dermatosis; Be dermopathic season occurred frequently spring.Spring climate variability.The lingering cold in existing the last days of winter has the scorching of midsummer again, and child's health immune system is immaturity still, and the viral dermatosis morbidity is more; The wind in spring is relatively drier, also is being mingled with various microorganisms, pollen, dust, and anaphylaxis dermatosis is also more common in children's.
The common viral dermatosis of children's in spring has chickenpox, rubella, erythema infectiosum, roseola infantum etc.This class disease incidence goes to toward " flu " symptom is arranged, even fever, poor, the general malaise of diet, but vesicle, erythema, the enlargement of table lymph node appear in skin then.
In the anaphylaxis dermatosis, common have eczema, pityriasis simplex, a papular urticaria etc.; Eczema has symmetry, pruritus, and the erythra multiformity, repeated relapsing four characteristics, skin can find that erythema, pimple, vesicle ooze out, take off multiple infringements such as genus, because pruritus often influences child's sleep, study; Above-mentioned treating for skin disease is generally given antiallergic agent such as chlorphenamine, antiviral class medicine, the sweet lotion of external stove, hydrocortisone frost etc.; External used medicine is owing to be that the chemical classes article usually can produce injury to child's skin, and endo-medicine not only has untoward reaction, and because its bitter in the mouth, usually can suffer child's the clothes of refusing; A kind of Chinese medicine preparation for the treatment of children ' s dermatosis of Chinese patent application (200410097113.4) and preparation method thereof, this Chinese medicine preparation comprises following weight portion Chinese medicine ingredients; Aloe: 1-10 part, Radix Sophorae Flavescentis: 5-40 part, the Radix Angelicae Dahuricae: 1-20 part, Cortex Dictamni: 5-20 part, Fructus Xanthii: 1-20 part, the Fructus Kochiae: 1-20 part, Cortex Phellodendri: 1-10 part, Folium Artemisiae Argyi: 1-20 part, Rhizoma Acori Graminei: 1-10, Radix Angelicae Sinensis: 1-5 part, Fructus Gleditsia: 5-40 part, this Chinese medicine mainly is coated on the affected part with the form of ointment, though this Chinese medicine preparation safely, have no side effect; But combining and can not playing enhancing is the effect of medicine, so the therapeutic effect of composition of medicine is not fairly obvious, can only plays the effect of alleviating surface symptoms, and can't effect a radical cure.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation that children ' s dermatosis such as eczema, urticaria, miliaria alba, dermatitis is had the good curing effect.
Solution of the present invention is based on motherland's medical science to children ' s dermatosis and pathogenetic understanding of complication and Therapeutic Principle thereof, with reference to the modern pharmacological research achievement, from motherland's medicine treasure-house, filters out heat-clearing and toxic substances removing, all medicines of dispelling wind for relieving itching.
Medicine of the present invention is made by following component: (consumption is a weight portion)
Radix Sophorae Flavescentis: 20-80, Cortex Phellodendri: 20-80, Fructus Cnidii: 20-80,
The Fructus Kochiae: 20-80, Radix Et Rhizoma Rhei: 10-30, Radix Gentianae: 5-20,
Rhizoma Acori Graminei: 10-30, the Radix Angelicae Dahuricae: 5-20, Fructus Forsythiae: 20-80,
Radix Saposhnikoviae: 5-20, Flos Lonicerae: 10-30, Herba Taraxaci: 10-30,
Poria: 20-80, Galla Chinensis: 5-20.
Formula optimization weight (part) ratio range of preparation medicine of the present invention is:
Radix Sophorae Flavescentis: 30-60, Cortex Phellodendri: 30-60, Fructus Cnidii: 30-60,
The Fructus Kochiae: 30-60, Radix Et Rhizoma Rhei: 15-25, Radix Gentianae: 8-15,
Rhizoma Acori Graminei: 15-25, the Radix Angelicae Dahuricae: 8-15, Fructus Forsythiae: 20-80,
Radix Saposhnikoviae: 8-15, Flos Lonicerae: 15-25, Herba Taraxaci: 15-25,
Poria: 30-60, Galla Chinensis: 8-15.
The optimum weight of medicine of the present invention (part) proportioning is:
Radix Sophorae Flavescentis: 50, Cortex Phellodendri: 50, Fructus Cnidii: 50,
The Fructus Kochiae: 10, Radix Et Rhizoma Rhei: 20, Radix Gentianae: 10,
Rhizoma Acori Graminei: 20, the Radix Angelicae Dahuricae: 10, Fructus Forsythiae: 50,
Radix Saposhnikoviae: 10, Flos Lonicerae: 20, Herba Taraxaci: 20,
Poria: 50, Galla Chinensis: 10.
In the above-mentioned Chinese medicine preparation that is used for the treatment of children ' s dermatosis, the described medicament of described medicament is the above a decoction of pharmaceutics; This decoction adopts decocting process commonly used, the volume ratio of frying in shallow oil well-done decoction cooling back and warm water is to blend in about 1: 50, after will suffering from dermopathic child clean back one month in the medicament that this is blent, ill child affected part secretions reduces, pruritus alleviates; The mechanism of action of Chinese medicine preparation of the present invention is as follows: wherein Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Sophorae Flavescentis have the effect of heat clearing away, antipruritic, removing dampness; Because three's property of medicine difference, adopt single medicine such as Radix Et Rhizoma Rhei high strong, to capture removing blood stasis with potent drugs power strong, easily hinder healthy energy and easily the child caused untoward reaction, but with single as then heat clearing away of Radix Sophorae Flavescentis, antipruritic, the removing dampness property of medicine is relatively poor, healing time is long; Fructus Cnidii has and dispels the wind, dampness, and parasiticidal effect, because a lot of dermatosiss use Fructus Cnidii not only to have in medicament of the present invention and dispel the wind owing to infect acarid and cause, dampness, and can kill acarid and other antibacterial; The Fructus Kochiae has the effect of clearing heat and expelling damp, dispelling wind for relieving itching; Radix Gentianae has heat clearing and damp drying, the effect of pathogenic fire purging arresting convulsion; Rhizoma Acori Graminei has eliminating phlegm, regulates the flow of vital energy, and invigorates blood circulation, the wind that looses, the effect of drying; The Radix Angelicae Dahuricae can promote metabolism, the delaying decrepitude of skin of skin; Fructus Forsythiae not only has heat clearing away, detoxifcation, eliminating stagnation, the repercussive effect, and its soup agent has an antibacterial action external, can suppress Bacillus typhi, Salmonella paratyphi, escherichia coli, dysentery bacterium, diphtheria corynebacterium and vibrio cholera, staphylococcus, streptococcus etc., it has good facilitation for the incrustation in child's skin affected part; Radix Saposhnikoviae has diffusing wind heat clearing away, the effect of detoxifying and relieving itching; Flos Lonicerae not only has heat-clearing and toxic substances removing, the bullate function of emaciation due to emotional upset of loosing, and to fully without any stimulation, can play the effect of skin moistening; Herba Taraxaci has heat-clearing and toxic substances removing, the effect of broad-spectrum antiseptic, and to anti-acne, folliculitis has certain curative effect; Poria not only has diuresis, can make urine amount and Na
+, K
+Output, increase, and the effective ingredient that its short sodium is discharged is the effect that pachymic acid plays eliminating toxin and beautifying the skin; And it can also play germ-resistant effect at interaction in vitro; Galla Chinensis has hemostasis, antidotal effect, can treat diseases such as skin eczema, toxic swelling, furuncle; The present invention adopts the compositions of said medicine to make medicament, and being based on potentiation is the drug combination pharmacological mechanism.Bring into play the synergism between medicine and improve curative effect; Drug combination has surpassed each medicine effect sum.
Therefore the present invention has the following advantages:
1. to select the homologous natural plants of medicated diet for use be raw material in the present invention, is drug combination pharmacological action mechanism treatment children ' s dermatosis based on potentiation on the pharmacology, and child's skin not only without any toxic and side effects, and is played moist effect;
2. Chinese medicine preparation of the present invention mainly uses when the child has a bath, and can not cause any misery to the child, and is easy to use.
The present invention to children ' s dermatosis particularly infantile eczema have excellent curative, treatment back is difficult for recurrence.
Introduce the present invention below and be used for the treatment of the clinical effect effect of the Chinese medicine preparation of children ' s dermatosis skin allergy experiment, the dermopathic pharmacodynamics of treatment and treatment eczema.
Skin anaphylactic test
With the SD rat of body weight 200 ± 20g, 10 every group, be divided into 3 groups at random, skin depilatory (the about 2cm of area
2) one group use water as negative control, one group with the zest medicine as positive control, another group gives Chinese medicine preparation of the present invention, the result shows that Chinese medicine preparation of the present invention can not produce as zest effects such as erythema, edema SD rat depilation skin.
Treat dermopathic pharmacodynamic action effect
Get 30 of newborn white mice, be divided into five groups, at 2~12 days ages, the depletion Staphylococcus aureus gives subcutaneous injection, per injection 0.1ml.Lax bulla appears in skin after 6~12 hours, is suffering from medicament and the antibiotic ointment matched group that is coated with various dose of the present invention on the Corium Mus skin, and result of the test is as follows:
Table 1 Chinese medicine preparation of the present invention results of pharmacodynamic test
Chinese medicine preparation of the present invention is compared with negative control group: p<0.01 this shows that Chinese medicine preparation of the present invention has good incrustation effect to the bulla on the dermatosis.
The clinical effect effect of treatment eczema
Randomly draw 250 of child patients, at 6 months~5 years old age, many pimples appear in back, both hands, two interior lower limb, and serious part is festered, and oozes out yellow liquid, pruritus unbearably, and afternoon is more serious, and be unwilling to fall asleep evening.
It is that effect was as shown in the table after 50 times water cleaned 3 months to child patient that the decoction that adopts Chinese medicine of the present invention to decoct is put into volume ratio:
Table 2 Chinese medicine preparation therapeutic outcome of the present invention relatively
Annotate: Chinese medicine preparation group of the present invention is compared with matched group: X
2=67.7, P<0.01.Illustrate that Chinese medicine preparation group of the present invention compared apparent difference with matched group, illustrate that Chinese medicine preparation of the present invention has good curative effect to eczema, and be difficult for recurrence.
The specific embodiment
Below by specific embodiment, technical scheme of the present invention is described in further detail; But the present invention is not limited to these embodiment
Percentage by weight proportioning by following tabulation takes by weighing following prescription
Table 3: the weight proportion (g) of embodiment 1~embodiment 5 each raw material
The production method of embodiment 1~5 is as follows
After getting earth pot and cleaning, put into the raw material of Chinese medicine of table 3 embodiment 1~5 weight and put into 2 liters of pure water, warm fire decocts, and decocts 90~100 ℃ of temperature, decoct 10~30 minutes after, leach medicament, pour out dregs of a decoction; I.e. Zhi the Chinese medicine preparation that is used for the treatment of children ' s dermatosis of the present invention.
Application Example:
Pouring the Chinese medicine preparation of above-mentioned preparation into volume ratio is in 1: 50 the warm water, puts into bathtub after stirring, and infant is placed on wherein soaked flushing with clean water at every turn 5~10 minutes then; Month secretions of bathing reduces, and pruritus alleviates, all incrustations of serious part, and bathing was fully recovered after 3 months, can not recur.
Specific embodiment described in the present invention only is that the present invention's spirit is illustrated.The technical staff of the technical field of the invention can make various modifications or replenishes or adopt similar mode to substitute described specific embodiment, but can't depart from spirit of the present invention or surmount the defined scope of appended claims.
Although the present invention has been made detailed explanation and has quoted some instantiations as proof, to those skilled in the art, only otherwise leave that the spirit and scope of the present invention can be done various variations or correction is obvious.
Claims (4)
1. a Chinese medicine preparation that is used for the treatment of children ' s dermatosis is characterized in that it is the medicament of being made by the following weight proportion raw material
Radix Sophorae Flavescentis: 20-80, Cortex Phellodendri: 20-80, Fructus Cnidii: 20-80,
The Fructus Kochiae: 20-80, Radix Et Rhizoma Rhei: 10-30, Radix Gentianae: 5-20,
Rhizoma Acori Graminei: 10-30, the Radix Angelicae Dahuricae: 5-20, Fructus Forsythiae: 20-80,
Radix Saposhnikoviae: 5-20, Flos Lonicerae: 10-30, Herba Taraxaci: 10-30,
Poria: 20-80, Galla Chinensis: 5-20.
2. the Chinese medicine preparation that is used for the treatment of children ' s dermatosis according to claim 1 is characterized in that the weight proportion of described each raw material is
Radix Sophorae Flavescentis: 30-60, Cortex Phellodendri: 30-60, Fructus Cnidii: 30-60,
The Fructus Kochiae: 30-60, Radix Et Rhizoma Rhei: 15-25, Radix Gentianae: 8-15,
Rhizoma Acori Graminei: 15-25, the Radix Angelicae Dahuricae: 8-15, Fructus Forsythiae: 20-80,
Radix Saposhnikoviae: 8-15, Flos Lonicerae: 15-25, Herba Taraxaci: 15-25,,
Poria: 30-60, Galla Chinensis: 8-15.
3. the Chinese medicine preparation that is used for the treatment of children ' s dermatosis according to claim 1 is characterized in that the weight proportion of described each raw material is
Radix Sophorae Flavescentis: 50, Cortex Phellodendri: 50, Fructus Cnidii: 50,
The Fructus Kochiae: 10, Radix Et Rhizoma Rhei: 20, Radix Gentianae: 10,
Rhizoma Acori Graminei: 20, the Radix Angelicae Dahuricae: 10, Fructus Forsythiae: 50,
Radix Saposhnikoviae: 10, Flos Lonicerae: 20, Herba Taraxaci: 20,
Poria: 50, Galla Chinensis: 10.
4. according to claim 1 or the 2 or 3 described Chinese medicine preparation that are used for the treatment of children ' s dermatosis, it is characterized in that described medicament is the above a decoction of pharmaceutics.
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Cited By (11)
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CN101797315A (en) * | 2010-04-02 | 2010-08-11 | 周建红 | Traditional Chinese medicine composition capable of treating various skin diseases |
CN101664497B (en) * | 2009-10-27 | 2011-04-13 | 张庆珍 | Pharmaceutical composition for treating pediatric dermatosis |
CN102293851A (en) * | 2011-08-26 | 2011-12-28 | 天津尖峰弗兰德医药科技发展有限公司 | Externally applied traditional Chinese medicine preparation for treating exudation type eczema in babies and preparation method thereof |
CN103263547A (en) * | 2013-05-23 | 2013-08-28 | 刘欣荣 | Traditional Chinese medicinal preparation for treating urticaria papulosa |
CN103638351A (en) * | 2013-11-29 | 2014-03-19 | 大连创达技术交易市场有限公司 | Traditional Chinese medicine formula for treating urticaria |
CN104689117A (en) * | 2015-03-18 | 2015-06-10 | 俞益武 | Traditional Chinese medicine washing liquor for controlling eczema and preparation method thereof |
CN105126000A (en) * | 2015-09-10 | 2015-12-09 | 于国庆 | External ointment for treating infantile eczema |
CN108434268A (en) * | 2018-06-26 | 2018-08-24 | 主嘉佳 | A kind of Chinese medicine preparation and preparation method thereof for treating dermatitis |
CN109106827A (en) * | 2018-09-25 | 2019-01-01 | 安徽兆龙食品有限公司 | A kind of preparation method and applications for the biological agent having no drug resistance |
CN109498782A (en) * | 2018-11-23 | 2019-03-22 | 嘉肖雄 | It is a kind of to treat dermopathic Chinese medicine and preparation method thereof |
CN109549902A (en) * | 2019-01-16 | 2019-04-02 | 史德良 | It is a kind of to improve and treat eczema, allergy, saliva rash, diaper rash, the composite skin care product of intertrigo and its application |
Family Cites Families (2)
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CN1053366C (en) * | 1995-12-05 | 2000-06-14 | 廖利平 | Chinese herbal medicine composition |
CN1238973A (en) * | 1998-06-12 | 1999-12-22 | 许世平 | 'Pikang' No.2 for treating dermatosis |
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CN101664497B (en) * | 2009-10-27 | 2011-04-13 | 张庆珍 | Pharmaceutical composition for treating pediatric dermatosis |
CN101797315A (en) * | 2010-04-02 | 2010-08-11 | 周建红 | Traditional Chinese medicine composition capable of treating various skin diseases |
CN101797315B (en) * | 2010-04-02 | 2012-01-25 | 周建红 | Traditional Chinese medicine composition capable of treating various skin diseases |
CN102293851A (en) * | 2011-08-26 | 2011-12-28 | 天津尖峰弗兰德医药科技发展有限公司 | Externally applied traditional Chinese medicine preparation for treating exudation type eczema in babies and preparation method thereof |
CN103263547B (en) * | 2013-05-23 | 2014-07-09 | 刘欣荣 | Traditional Chinese medicinal preparation for treating urticaria papulosa |
CN103263547A (en) * | 2013-05-23 | 2013-08-28 | 刘欣荣 | Traditional Chinese medicinal preparation for treating urticaria papulosa |
CN103638351A (en) * | 2013-11-29 | 2014-03-19 | 大连创达技术交易市场有限公司 | Traditional Chinese medicine formula for treating urticaria |
CN104689117A (en) * | 2015-03-18 | 2015-06-10 | 俞益武 | Traditional Chinese medicine washing liquor for controlling eczema and preparation method thereof |
CN105126000A (en) * | 2015-09-10 | 2015-12-09 | 于国庆 | External ointment for treating infantile eczema |
CN108434268A (en) * | 2018-06-26 | 2018-08-24 | 主嘉佳 | A kind of Chinese medicine preparation and preparation method thereof for treating dermatitis |
CN109106827A (en) * | 2018-09-25 | 2019-01-01 | 安徽兆龙食品有限公司 | A kind of preparation method and applications for the biological agent having no drug resistance |
CN109498782A (en) * | 2018-11-23 | 2019-03-22 | 嘉肖雄 | It is a kind of to treat dermopathic Chinese medicine and preparation method thereof |
CN109549902A (en) * | 2019-01-16 | 2019-04-02 | 史德良 | It is a kind of to improve and treat eczema, allergy, saliva rash, diaper rash, the composite skin care product of intertrigo and its application |
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