CN103263547B - Traditional Chinese medicinal preparation for treating urticaria papulosa - Google Patents

Traditional Chinese medicinal preparation for treating urticaria papulosa Download PDF

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CN103263547B
CN103263547B CN201310216645.4A CN201310216645A CN103263547B CN 103263547 B CN103263547 B CN 103263547B CN 201310216645 A CN201310216645 A CN 201310216645A CN 103263547 B CN103263547 B CN 103263547B
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CN103263547A (en
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刘欣荣
于冠礼
王玉芹
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Wang Lihua
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Abstract

The invention discloses a traditional Chinese medicinal preparation for treating the urticaria papulosa. The traditional Chinese medicinal preparation is prepared from clinopodium herb, caryopteris incana, radices sileris, groundsel, vernonia patula, fructus kochiae, salix chienii, dregea volubilis, awned goosefoot, rock pine, chondrus, sanxiao herb, white atractylodes rhizome, fructus cnidii, fructus forsythiae, rhizoma acori graminei and liquorice. The traditional Chinese medicinal preparation can be clinically used for treating urticaria papulosa.

Description

A kind of Chinese medicine preparation for the treatment of papular urticaria
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine preparation for the treatment of papular urticaria.
Background technology
Papular urticaria is summer and autumn one of common dermatosiss, and Chinese medicine is called urticaria papulose.Very scratchy, can there is water lump in severe patient, and erythra often occurs with rising one after another.Cause the reason of papular urticaria, modern medicine is thought may relevant with some sting (as Pulex irritans, louse, mosquito, illness wax, scabies wax etc.).These insecticides are by contact or wave with the wind to human body, bite skin and cause primary disease.At present, antihistamine, amcinonide treatment for Western medicine, short term effect is sure, and drug withdrawal is easily recurrence, and through clinical discovery, Chinese drugs agentia of the present invention has good result to papular urticaria.
Summary of the invention
The object of the present invention is to provide the Chinese medicine preparation of the treatment papular urticaria that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Herba clinopodii confinis (Herba Clinopodii Gracilis), Herba Caryopteridis Incanae, Radix Saposhnikoviae, Herba Senecionis Scandentis, Herba Vernoniae Patulae, the Fructus Kochiae, Salix chienii Cheng, Herba Dregeae volubilis, Herba Chenopodii Aristati, Lycopodium chinense Christ, chondrus ocellatus Holmes, Herba Trifolii Pepentis, the Rhizoma Atractylodis Macrocephalae, Fructus Cnidii, Fructus Forsythiae, Rhizoma Acori Graminei, Radix Glycyrrhizae, according to certain compatibility requirement, through being processed into.
Preparing Chinese medicine preparation of the present invention is made up of following raw material medicaments: Herba clinopodii confinis (Herba Clinopodii Gracilis) 40-60 part, Herba Caryopteridis Incanae 30-50 part, Radix Saposhnikoviae 30-50 part, Herba Senecionis Scandentis 30-50 part, Herba Vernoniae Patulae 30-50 part, Fructus Kochiae 20-40 part, Salix chienii Cheng 20-40 part, Herba Dregeae volubilis 20-40 part, Herba Chenopodii Aristati 20-40 part, Lycopodium chinense Christ 20-40 part, chondrus ocellatus Holmes 15-30 part, Herba Trifolii Pepentis 15-30 part, Rhizoma Atractylodis Macrocephalae 15-30 part, Fructus Cnidii 10-15 part, Fructus Forsythiae 10-15 part, Rhizoma Acori Graminei 10-15 part, Radix Glycyrrhizae 8-12 part.
Optimum weight part of Chinese medicine preparation crude drug of the present invention is: 50 parts of Herba clinopodii confinis (Herba Clinopodii Gracilis)s, 40 parts of Herba Caryopteridis Incanaes, 40 parts of Radix Saposhnikoviaes, 40 parts of Herba Senecionis Scandentiss, 40 parts of Herba Vernoniae Patulae, 30 parts of the Fructus Kochiae, 30 parts of Salix chienii Cheng, 30 parts of Herba Dregeae volubiliss, 30 parts of Herba Chenopodii Aristati, 30 parts of Lycopodium chinense Christs, 20 parts of chondrus ocellatus Holmes, 20 parts of Herba Trifolii Pepentiss, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 13 parts of Fructus Cnidiis, 13 parts of Fructus Forsythiaes, 13 parts of Rhizoma Acori Graminei, 10 parts, Radix Glycyrrhizae.
The pharmacological action of Chinese medicine of the present invention is as follows:
Herba clinopodii confinis (Herba Clinopodii Gracilis): bitter, pungent, cool.Expelling wind and clearing away heat, circulation of qi promoting hemostasis, removing toxic substances and promoting subsidence of swelling.For cat fever, abdominal pain due to retention of food, vomiting, has loose bowels, dysentery, diphtheria, laryngopharynx swelling and pain, erysipelas carbuncle, urticaria, the diseases such as traumatic injury.
Herba Caryopteridis Incanae: pungent, warm.Dispelling wind to relieve the exterior syndrome, the dehumidifying of dispeling cold, eliminating stasis to stop pain.Clinical in anemofrigid cold, headache, cough, coldness and pain in the epigastrium, dyspeptic vomiting and diarrhea, cold stasis of blood dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal, anemofrigid-damp arthralgia, traumatic injury congestive edema, the diseases such as eczema.
Radix Saposhnikoviae: pungent, sweet, tepor.Return bladder, liver, spleen channel.Deliver loose wind, removing dampness to relieve pain, relieving convulsion, antidiarrheal.For headache due to common cold, rubella pruritus, rheumatic arthralgia, tetanus card etc.
Herba Senecionis Scandentis: bitter in the mouth, pungent, cold in nature.Heat-clearing and toxic substances removing, improving acuity of vision and removing nebula, killing parasites for relieving itching.For influenza, upper respiratory tract infection, pneumonia, acute tonsillitis etc.
Herba Vernoniae Patulae: bitter, pungent, flat.Fresh breeze heat clearing away, eliminating damp, detoxifying, dissipating blood stasis for subsidence of swelling.Clinical in cold, fever, malaria, hypertension, has loose bowels, dysentery, rheumatic arthralgia, eczema, urticaria, furuncle, mastitis, the tuberculosis of cervical lymph nodes, the diseases such as traumatic injury.
The Fructus Kochiae: bitter, cold, return urinary bladder channel.Clearing away heat-damp and promoting diuresis is antipruritic.For skin rubella, eczema, whole body pruritus.
Salix chienii Cheng: pungent, bitter, cold.Heat-clearing and toxic substances removing, dispelling wind for relieving itching, pain relieving.For cold, fever, laryngopharynx swelling and pain, skin pruritus, cystitis, urethritis, traumatic pain.
Herba Dregeae volubilis: pungent, bitter, cool.Attach to the lung and stomach meridians.Dispel the wind, dehumidifying, pain relieving, clearing heat to ease the stomach.For flu, rheumatic arthritis, lumbago, vomiting during pregnancy, the esophageal carcinoma, gastric cancer etc.
Herba Chenopodii Aristati: light, flat.Invigorate blood circulation, regulating menstruation, dispelling wind for relieving itching.For menorrhagia, dysmenorrhea, amenorrhea, allergic dermatitis, the diseases such as urticaria.
Lycopodium chinense Christ: bitter, puckery, flat.Expelling wind and removing dampness, reducing swelling and alleviating pain, heat-clearing and toxic substances removing.Ache for podomere, traumatic injury, herpes zoster, the diseases such as urticaria.
Chondrus ocellatus Holmes: sweet, salty, cold.Return large intestine, stomach warp.Heat-clearing and toxic substances removing, stomach function regulating relieving constipation.For laryngopharynx swelling and pain, traumatic injury, flu cold and heat, mumps, gastralgia, dryness of the intestine constipation etc.
Herba Trifolii Pepentis: sweet, flat.GUIXIN, spleen channel.Heat clearing away, removing heat from blood, mind calming.For insane disease, bleeding hemorrhoids, the diseases such as scleroma lump.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm.Return spleen, stomach warp.Air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive.For deficiency of spleen-QI and stomach-QI, transporting is unable, anorexia and loose stool, and distension and fullness in the abdomen, insufficiency of the spleen water retention, and be phlegm retention, edema, dysuria, frequent fetal movement etc.
Fructus Cnidii: acrid, bitter, warm, return kidney channel.Killing parasites for relieving itching, warming the kidney to invigorate YANG.For eczema, scabies, remove stagnated QI, sharp joint, epilepsy malignant boil outward.
Fructus Forsythiae: bitter, be slightly cold, return lung, the heart, gallbladder meridian.Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.For carbuncle sore tumefacting virus, scrofula sucutaneous nodule.
Rhizoma Acori Graminei: pungent, bitter, tepor, GUIXIN, liver, spleen channel.Eliminate phlegm for resuscitation, removing dampness to restore normal function of the stomach, mind calming Fructus Alpiniae Oxyphyllae.For calentura coma, forgetful, insomnia, tinnitus.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine.For severe palpitation, the irregularly intermittent and regularly intermittent pulse of deficiency of heart-QI, pathopyretic ulcer, laryngopharynx swelling and pain.
Papular urticaria belongs to the categories such as the traditional Chinese medical science " popular urticaria ", " chickenpox stupid wet ", and pathogenesis is insufficiency of the spleen wet accumulateing of plain body, diseases caused by exogenous pathogenic factor ailment said due to cold or exposure insect poison or internal damage caused by dyspepsia, and damp-stagnancy heat-transformation, initiates skin ulcer and falls ill.In the present invention, Herba clinopodii confinis (Herba Clinopodii Gracilis) is monarch drug, expelling wind and clearing away heat, circulation of qi promoting removing toxic substances, and Herba Caryopteridis Incanae dispelling wind to relieve the exterior syndrome, Radix Saposhnikoviae are delivered loose wind, Herba Senecionis Scandentis heat-clearing and toxic substances removing, antipruritic, Herba Vernoniae Patulae eliminating damp, detoxifying, is ministerial drug, and Fructus Kochiae clearing away heat-damp and promoting diuresis is antipruritic, Salix chienii Cheng heat-clearing and toxic substances removing is antipruritic, Herba Dregeae volubilis clearing heat to ease the stomach, Herba Chenopodii Aristati dispelling wind for relieving itching, Lycopodium chinense Christ heat-clearing and toxic substances removing, the removing toxic substances of chondrus ocellatus Holmes stomach function regulating, Herba Trifolii Pepentis heat clearing away, mind calming, Rhizoma Atractylodis Macrocephalae the spleen strengthening and damp drying, Fructus Cnidii is antipruritic, Fructus Forsythiae removing toxic substances, Rhizoma Acori Graminei stomach function regulating mind calming, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.All medicines are played invigorating spleen to remove dampness altogether, stomach function regulating mind calming, and dispelling wind and heat pathogens, antipruritic effect, reaches the object for the treatment of papular urticaria.
Chinese medicine preparation of the present invention was in 2005 to 2011 the routine patients of clinical observation papular urticaria 153, and clinical report is as follows:
1, physical data
In 153 routine patients, women's 73 examples, male's 80 examples, at minimum 19 years old of age, maximum 65 years old, disease time was many at 2 months to 4 years, 20.3 years old mean age.
2, diagnostic criteria
" traditional Chinese medical science syndromic diagnosis standard " of promulgating with reference to State Administration of Traditional Chinese Medicine
(1) break out, skin lesion is for differing in size, the edema speckle that shape differs, and boundary is obvious;
(2) while rising when erythra, fall, violent pruritus, skin lesion appearing without definite location, steps back and leaves no trace;
(3) some cases can have abdominal pain diarrhea, or has the symptom such as heating, arthralgia, and severe patient can have dyspnea, even causes and suffocates;
(4) the dermatograph test positive;
(5) erythra more or was not repeatedly interrupted outbreak above through 3 months.
3, Therapeutic Method
3.1 prescriptions: Herba clinopodii confinis (Herba Clinopodii Gracilis) 50g, Herba Caryopteridis Incanae 40g, Radix Saposhnikoviae 40g, Herba Senecionis Scandentis 40g, Herba Vernoniae Patulae 40g, Fructus Kochiae 30g, Salix chienii Cheng 30g, Herba Dregeae volubilis 30g, Herba Chenopodii Aristati 30g, Lycopodium chinense Christ 30g, chondrus ocellatus Holmes 20g, Herba Trifolii Pepentis 20g, Rhizoma Atractylodis Macrocephalae 20g, Fructus Cnidii 13g, Fructus Forsythiae 13g, Rhizoma Acori Graminei 13g, Radix Glycyrrhizae 10g.
3.2 preparation methoies: said medicine routinely technique is made decoction.
3.3 instructions of taking: each 1 dose, every day 2 times.
4, therapeutic outcome:
4.1 criterion of cure:
Recovery from illness: deflorescence, occur without new rash, do not itch, leave pigmentation;
Effective: erythra more than 70% disappears, itch and alleviate, substantially occur without new rash;
Effective: deflorescence more than 50%, is itched and alleviated, but still have a little new rash to occur;
Invalid: deflorescence less than 50%, to itch without alleviating, new rash still occurs in batch.
4.2 results: in 153 routine patients, cure 95 examples (62.1%), effective 35 examples (22.8%), effective 23 examples (15.1%), total effective rate 100%.The present invention is used for the treatment of the Chinese medicine preparation of papular urticaria, proves through clinical trial, and successful, curative effect is outstanding.
5, model case
5.1 Zhao, female, plays erythra more than 6 weeks repeatedly, and expectorant is itched acutely, affects work, sleep, whenever recurrence in summer, once takes antihistaminic etc., DeGrain in recent years.Check: trunk, extremity are dispersed in Semen Glycines size, redness or kermesinus pimple and pigmentation spots, and both legs and foot are obvious, can water breakthrough lump in part pimple or ooze out.There is indentation on pale tongue, limit, and tongue is greasy in vain, rolling pulse.Be diagnosed as papular urticaria, take medicine of the present invention.Further consultation after one week, symptom alleviates.Take again one week, transference cure.After drug withdrawal in the 3rd week, symptom is not reaccessed, and within 1 year, follows up a case by regular visits to not recurrence.
5.2 Liu,, there is papular urticaria summer in female, to the autumn subtract, the winter more, outbreak repeatedly.Disease sees that whole body is dispersed in papular urticaria, and waist and ankle week, more so acute pruritus, accompanied burning sensation, increases the weight of whenever about the period of the day from 3 am to 5 am, vexed, fear of cold, and spontaneous perspiration, large dry stool, xerostomia is wanted cold drink, and light red tongue is tender, and there is indentation on limit, white and thin fur, thready pulse is short.Be diagnosed as papular urticaria.Take medicine of the present invention, treat after 3 days, erythra all disappears, and has no newborn.Following the service Chinese medicine 2 weeks, to consolidate curative effect, follows up a case by regular visits to and does not recur half a year.
5.3 grandsons, man, disease sees that skin distributes, pale red pimple, there is phlysis on top, has scratch around, whenever the period of the day from 3 am to 5 am conscious pimple hectic fever, violent pruritus, vexed, sweating, xerostomia, micro-hardship, large dry stool, light red tongue, yellow and thin fur, thready and rapid pulse.Be diagnosed as papular urticaria.Take after 3 doses of medicines of the present invention, symptom alleviates, and continues to take 2 weeks, and pruritus and skin lesion disappear, and pays a return visit so far not recurrence.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated, and following this embodiment does not only limit the present invention for the present invention is described.
Embodiment 1, treating a Chinese medicine preparation for papular urticaria, is to be made up of Herba clinopodii confinis (Herba Clinopodii Gracilis) 40g, Herba Caryopteridis Incanae 30g, Radix Saposhnikoviae 30g, Herba Senecionis Scandentis 30g, Herba Vernoniae Patulae 30g, Fructus Kochiae 20g, Salix chienii Cheng 20g, Herba Dregeae volubilis 20g, Herba Chenopodii Aristati 20g, Lycopodium chinense Christ 20g, chondrus ocellatus Holmes 15g, Herba Trifolii Pepentis 15g, Rhizoma Atractylodis Macrocephalae 15g, Fructus Cnidii 10g, Fructus Forsythiae 10g, Rhizoma Acori Graminei 10g, Radix Glycyrrhizae 8g.
Embodiment 2, treating a Chinese medicine preparation for papular urticaria, is to be made up of Herba clinopodii confinis (Herba Clinopodii Gracilis) 50g, Herba Caryopteridis Incanae 40g, Radix Saposhnikoviae 40g, Herba Senecionis Scandentis 40g, Herba Vernoniae Patulae 40g, Fructus Kochiae 30g, Salix chienii Cheng 30g, Herba Dregeae volubilis 30g, Herba Chenopodii Aristati 30g, Lycopodium chinense Christ 30g, chondrus ocellatus Holmes 20g, Herba Trifolii Pepentis 20g, Rhizoma Atractylodis Macrocephalae 20g, Fructus Cnidii 13g, Fructus Forsythiae 13g, Rhizoma Acori Graminei 13g, Radix Glycyrrhizae 10g.
Embodiment 3, treating a Chinese medicine preparation for papular urticaria, is to be made up of Herba clinopodii confinis (Herba Clinopodii Gracilis) 60g, Herba Caryopteridis Incanae 50g, Radix Saposhnikoviae 50g, Herba Senecionis Scandentis 50g, Herba Vernoniae Patulae 50g, Fructus Kochiae 40g, Salix chienii Cheng 40g, Herba Dregeae volubilis 40g, Herba Chenopodii Aristati 40g, Lycopodium chinense Christ 40g, chondrus ocellatus Holmes 30g, Herba Trifolii Pepentis 30g, Rhizoma Atractylodis Macrocephalae 30g, Fructus Cnidii 15g, Fructus Forsythiae 15g, Rhizoma Acori Graminei 15g, Radix Glycyrrhizae 12g.

Claims (2)

1. treat a Chinese medicine composition for papular urticaria, it is characterized in that it is to be made up of following raw material medicaments:
Herba clinopodii confinis (Herba Clinopodii Gracilis) 40-60 part, Herba Caryopteridis Incanae 30-50 part, Radix Saposhnikoviae 30-50 part, Herba Senecionis Scandentis 30-50 part, Herba Vernoniae Patulae 30-50 part,
Fructus Kochiae 20-40 part, Salix chienii Cheng 20-40 part, Herba Dregeae volubilis 20-40 part, Herba Chenopodii Aristati 20-40 part, Lycopodium chinense Christ 20-40 part,
Chondrus ocellatus Holmes 15-30 part, Herba Trifolii Pepentis 15-30 part, Rhizoma Atractylodis Macrocephalae 15-30 part, Fructus Cnidii 10-15 part, Fructus Forsythiae 10-15 part,
Rhizoma Acori Graminei 10-15 part, Radix Glycyrrhizae 8-12 part.
2. Chinese medicine composition according to claim 1, is characterized in that it is to be made up of following raw material medicaments:
50 parts of Herba clinopodii confinis (Herba Clinopodii Gracilis)s, 40 parts of Herba Caryopteridis Incanaes, 40 parts of Radix Saposhnikoviaes, 40 parts of Herba Senecionis Scandentiss, 40 parts of Herba Vernoniae Patulae,
30 parts of the Fructus Kochiae, 30 parts of Salix chienii Cheng, 30 parts of Herba Dregeae volubiliss, 30 parts of Herba Chenopodii Aristati, 30 parts of Lycopodium chinense Christs,
20 parts of chondrus ocellatus Holmes, 20 parts of Herba Trifolii Pepentiss, 20 parts of the Rhizoma Atractylodis Macrocephalaes, 13 parts of Fructus Cnidiis, 13 parts of Fructus Forsythiaes,
13 parts of Rhizoma Acori Graminei, 10 parts, Radix Glycyrrhizae.
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Citations (3)

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Publication number Priority date Publication date Assignee Title
CN101152443A (en) * 2007-09-24 2008-04-02 徐大洋 Traditional Chinese medicine for treating urticaria, that is for benefiting Qi and eliminating damp
CN101156925A (en) * 2007-07-06 2008-04-09 周朝红 A traditional Chinese medicine preparation for treating children dermatosis
CN102000222A (en) * 2010-10-29 2011-04-06 荣成市新技术应用研究所 Traditional Chinese medicine for treating urticaria

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101156925A (en) * 2007-07-06 2008-04-09 周朝红 A traditional Chinese medicine preparation for treating children dermatosis
CN101152443A (en) * 2007-09-24 2008-04-02 徐大洋 Traditional Chinese medicine for treating urticaria, that is for benefiting Qi and eliminating damp
CN102000222A (en) * 2010-10-29 2011-04-06 荣成市新技术应用研究所 Traditional Chinese medicine for treating urticaria

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Title
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周维屏.108例丘疹性荨麻疹的辨证治疗.《湖南中医学院学报》.1990,第10卷(第03期),138-139.

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